{"id":49441,"date":"2018-09-25T01:00:00","date_gmt":"2018-09-26T01:58:20","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/26\/%e3%80%90%e6%8b%9b%e5%8b%9f%e6%82%a3%e8%80%85%e3%80%91%e8%af%84%e4%bb%b7bat4306f%e5%9c%a8%e5%a4%8d%e5%8f%91%e9%9a%be%e6%b2%bbcd20%e9%98%b3%e6%80%a7b%e7%bb%86%e8%83%9e%e6%80%a7%e9%9d%9e%e9%9c%8d\/"},"modified":"2018-09-26T09:58:20","modified_gmt":"2018-09-26T01:58:20","slug":"%e3%80%90%e6%8b%9b%e5%8b%9f%e6%82%a3%e8%80%85%e3%80%91%e8%af%84%e4%bb%b7bat4306f%e5%9c%a8%e5%a4%8d%e5%8f%91%e9%9a%be%e6%b2%bbcd20%e9%98%b3%e6%80%a7b%e7%bb%86%e8%83%9e%e6%80%a7%e9%9d%9e%e9%9c%8d","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/49441\/","title":{"rendered":"\u3010\u62db\u52df\u60a3\u8005\u3011\u8bc4\u4ef7BAT4306F\u5728\u590d\u53d1\u96be\u6cbbCD20\u9633\u6027B\u7ec6\u80de\u6027\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\u60a3\u8005\u4e2d\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u548c\u836f\u4ee3\u52a8\u529b\u5b66\u7684I\u671f\u4e34\u5e8a\u7814\u7a76"},"content":{"rendered":"
\n
<\/mpcps><\/section>\n

<\/span><\/span>
<\/p>\n

1.       <\/span><\/span>\u8bd5\u9a8c\u836f\u7269\u7b80\u4ecb<\/span><\/span><\/p>\n

BAT4306F<\/span>\u662f\u767e\u5965\u6cf0\u5f00\u53d1\u7684\u65b0\u4e00\u4ee3\u6297<\/span>CD20<\/span>\u4eba\u6e90\u5316\u6297\u4f53\uff0c\u5b83\u4e0e\u7f8e\u7f57\u534e\u7684\u4f5c\u7528\u8868\u4f4d\u4e0d\u540c\uff0c\u80fd\u76f4\u63a5\u8bf1\u5bfc<\/span>B<\/span>\u7ec6\u80de\u51cb\u4ea1\u3002\u901a\u8fc7\u5bf9\u6297\u4f53\u7684\u7cd6\u57fa\u5316\u8fdb\u884c\u6539\u9020\uff0c\u8fdb\u4e00\u6b65\u589e\u5f3a\u4e86<\/span>BAT4306F<\/span>\u7684<\/span>ADCC<\/span>\u6548\u5e94\u3002<\/span><\/span><\/p>\n

\u672c\u8bd5\u9a8c\u9002\u5e94\u75c7\u662f<\/span>\u590d\u53d1<\/span>\/<\/span>\u96be\u6cbb<\/span>CD20<\/span>\u9633\u6027<\/span>B<\/span>\u7ec6\u80de\u6027\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624<\/span>\u3002<\/span><\/span><\/p>\n

 <\/span><\/p>\n

2.       <\/span><\/span>\u8bd5\u9a8c\u76ee\u7684<\/span><\/span><\/p>\n

1<\/span>\u3001\u8bc4\u4ef7<\/span>BAT4306F<\/span>\u6ce8\u5c04\u6db2\u5242\u91cf\u9012\u589e\u5728<\/span>CD20<\/span>\u9633\u6027<\/span>B<\/span>\u7ec6\u80de\u6dcb\u5df4\u7624\u60a3\u8005\u4e2d\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\uff0c\u4ee5\u786e\u5b9a\u6700\u5927\u8010\u53d7\u5242\u91cf\uff08<\/span>MTD<\/span>\uff09\u3001\u5242\u91cf\u9650\u5236\u6027\u6bd2\u6027\uff08<\/span>DLT<\/span>\uff09\u548c\u63a8\u8350<\/span>II<\/span>\u671f\u4e34\u5e8a\u7814\u7a76\u7684\u4f7f\u7528\u5242\u91cf\uff08<\/span>RP2D<\/span>\uff09\uff1b<\/span> <\/span><\/span><\/p>\n

2<\/span>\u3001\u7814\u7a76<\/span>BAT4306F<\/span>\u6ce8\u5c04\u6db2\u7684\u836f\u4ee3\u52a8\u529b\u5b66\u7279\u5f81\u3002<\/span><\/span><\/p>\n

 <\/span><\/p>\n

3.       <\/span><\/span>\u8bd5\u9a8c\u8bbe\u8ba1<\/span><\/span><\/p>\n

\u8bd5\u9a8c\u5206\u7c7b\uff1a\u5b89\u5168\u6027<\/span><\/p>\n

\u8bd5\u9a8c\u5206\u671f\uff1a<\/span> I<\/span>\u671f<\/span><\/span><\/p>\n

\u8bbe\u8ba1\u7c7b\u578b\uff1a\u5355\u81c2\u8bd5\u9a8c<\/span><\/p>\n

\u968f\u673a\u5316\uff1a<\/span>   <\/span>\u975e\u968f\u673a\u5316<\/span><\/span><\/p>\n

\u76f2\u6cd5\uff1a<\/span>        <\/span>\u5f00\u653e<\/span><\/span><\/p>\n

\u8bd5\u9a8c\u8303\u56f4\uff1a\u56fd\u5185\u8bd5\u9a8c<\/span> <\/span><\/span><\/p>\n

\u5165\u7ec4\u4eba\u6570\uff1a<\/span> 18-24<\/span>\u4eba<\/span><\/span><\/p>\n

 <\/span><\/p>\n

4.       <\/span><\/span>\u5165\u9009\u6807\u51c6<\/span><\/span><\/p>\n

1  <\/span>\u540c\u610f\u53c2\u52a0\u8bd5\u9a8c\uff0c\u5e76\u4e66\u9762\u7b7e\u7f72\u77e5\u60c5\u540c\u610f\u4e66<\/span><\/span><\/p>\n

2  <\/span>\u5e74\u9f84<\/span>18-75<\/span>\u5468\u5c81\uff0c\u6027\u522b\u4e0d\u9650<\/span><\/span><\/p>\n

3  <\/span>\u75c5\u7406\u7ec4\u7ec7\u5b66\u5df2\u8bc1\u660e<\/span>CD20<\/span>\u9633\u6027\uff0c\u65e2\u5f80\u81f3\u5c11\u63a5\u53d7<\/span>1<\/span>\u4e2a\u7597\u7a0b\u7684\u6807\u51c6\u6297\u80bf\u7624\u65b9\u6848\u6cbb\u7597\u7684\u590d\u53d1<\/span>\/<\/span>\u96be\u6cbb<\/span>\/<\/span>\u8fdb\u5c55\u7684\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\u60a3\u8005<\/span><\/span><\/p>\n

4  <\/span>\u5177\u6709\u81f3\u5c11\u4e00\u4e2a\u53ef\u6d4b\u91cf\u7684\u75c5\u7076\uff1a<\/span>CLL<\/span>\u60a3\u8005\u5355\u514b\u9686<\/span>B<\/span>\u7ec6\u80de\u2265<\/span>5<\/span>\u2573<\/span>109\/L<\/span>\u3002<\/span>WM<\/span>\u60a3\u8005<\/span>IgM<\/span>\u5927\u4e8e<\/span>2<\/span>\u500d\u6b63\u5e38\u503c\u4e0a\u9650\u3002<\/span>CLL<\/span>\u548c<\/span>WM<\/span>\u4ee5\u5916\u7684\u60a3\u8005\uff0c\u6dcb\u5df4\u7ed3\u75c5\u7076\u4efb\u4e00\u957f\u5f84\u2265<\/span>1.5cm<\/span>\u6216\u7ed3\u5916\u75c5\u7076\u4efb\u4e00\u957f\u5f84<\/span>>1cm <\/span><\/span><\/p>\n

5  <\/span>\u5982\u679c\u4ee5\u5f80\u653e\u3001\u5316\u7597\u5f15\u8d77\u6bd2\u526f\u53cd\u5e94\uff0c\u5219\u9700\u8981\u6062\u590d\u81f3\u2264<\/span>1<\/span>\u7ea7\u6216\u8f6c\u5f52\u81f3\u57fa\u7ebf\u503c\u6216\u88ab\u5224\u5b9a\u4e0d\u53ef\u9006\uff08\u8131\u53d1\u548c\u2264<\/span>2<\/span>\u7ea7\u795e\u7ecf\u6bd2\u6027\u9664\u5916\uff09<\/span> <\/span><\/span><\/p>\n

6  <\/span>\u60a3\u8005<\/span>ECOG <\/span>\u8bc4\u5206\u4e3a<\/span>0<\/span>\uff0d<\/span>2<\/span>\u5206<\/span><\/span><\/p>\n

7  <\/span>\u9884\u671f\u751f\u5b58\u671f\u81f3\u5c11\u4e3a<\/span>6<\/span>\u4e2a\u6708<\/span><\/span><\/p>\n

8  <\/span>\u80b2\u9f84\u5973\u6027\u53d7\u8bd5\u8005\u7684\u8840\u6e05\u598a\u5a20\u8bd5\u9a8c\u5448\u9634\u6027<\/span><\/span><\/p>\n

 <\/span><\/p>\n

5.       <\/span><\/span>\u6392\u9664\u6807\u51c6<\/span><\/span><\/p>\n

1  <\/span>\u9996\u6b21\u7ed9\u836f\u524d<\/span>3<\/span>\u4e2a\u6708\u5185\u4f7f\u7528\u8fc7\u4efb\u4f55\u7814\u7a76\u7528\u5355\u514b\u9686\u6297\u4f53\u6cbb\u7597<\/span><\/span><\/p>\n

2  <\/span>\u65e2\u5f80\u4f7f\u7528\u8fc7\u4efb\u4f55\u6297\u764c\u75ab\u82d7\uff0c\u6216\u7814\u7a76\u7ed9\u836f\u524d<\/span>3<\/span>\u4e2a\u6708\u5185\u4f7f\u7528\u8fc7<\/span>HPV<\/span>\u75ab\u82d7<\/span><\/span><\/p>\n

3  <\/span>\u9996\u6b21\u7ed9\u836f\u524d<\/span>3<\/span>\u4e2a\u6708\u5185\u4f7f\u7528\u8fc7\u6297<\/span>CD20<\/span>\u5355\u6297\u6cbb\u7597\u7684<\/span><\/span><\/p>\n

4  <\/span>\u9996\u6b21\u7ed9\u836f\u524d<\/span>3<\/span>\u4e2a\u6708\u5185\u4f7f\u7528\u8fc7\u653e\u5c04\u514d\u75ab\u7597\u6cd5<\/span><\/span><\/p>\n

5  <\/span>\u9996\u6b21\u7ed9\u836f\u524d<\/span>2<\/span>\u5468\u5185\u63a5\u53d7\u8fc7\u8f93\u8840\u3001\u4fc3\u7ea2\u7ec6\u80de\u751f\u6210\u7d20\u3001\u7c92\u7ec6\u80de\u96c6\u843d\u523a\u6fc0\u56e0\u5b50\u6216\u7c92\u7ec6\u80de<\/span>–<\/span>\u5de8\u566c\u7ec6\u80de\u96c6\u843d\u523a\u6fc0\u56e0\u5b50\u7684\u6cbb\u7597<\/span><\/span><\/p>\n

6  <\/span>\u9996\u6b21\u7ed9\u836f\u524d<\/span>3<\/span>\u4e2a\u6708\u8fdb\u884c\u8fc7\u9020\u8840\u5e72\u7ec6\u80de\u79fb\u690d\u6216\u8ba1\u5212\u5728<\/span>3<\/span>\u4e2a\u6708\u5185\u8fdb\u884c\u9020\u8840\u5e72\u7ec6\u80de\u79fb\u690d\u7684<\/span><\/span><\/p>\n

7  <\/span>\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u4fb5\u72af\u6216\u9885\u8111\u795e\u7ecf\u75c5\u53d8\u7684\u8bc1\u636e\u6216\u75c5\u53f2<\/span><\/span><\/p>\n

8  <\/span>\u5e76\u53d1\u6709\u5176\u4ed6\u6076\u6027\u80bf\u7624\u8005\uff08\u5df2\u7ecf\u6cbb\u6108\u7684\u539f\u4f4d\u5bab\u9888\u764c\uff0c\u76ae\u80a4\u764c\uff0c\u83b7\u5f97\u5b8c\u5168\u7f13\u89e3\uff1e<\/span>5<\/span>\u5e74\u7684\u4e73\u817a\u764c\u3001\u9ed1\u8272\u7d20\u7624\u9664\u5916\uff09<\/span><\/span><\/p>\n

9  <\/span>\u5176\u4ed6\u4e25\u91cd\u7684\u3001\u65e0\u6cd5\u63a7\u5236\u7684\u4f34\u968f\u75be\u75c5\uff0c\u5305\u62ec\u4f46\u4e0d\u9650\u4e8e\uff1a\u6d3b\u52a8\u6027\u611f\u67d3\u3001\u4e0d\u80fd\u63a7\u5236\u7684\u7cd6\u5c3f\u75c5\u3001\u4e0d\u80fd\u63a7\u5236\u7684\u9ad8\u8840\u538b\u75c5\u7b49<\/span><\/span><\/p>\n

10  <\/span>\u9996\u6b21\u7ed9\u836f\u524d<\/span>4<\/span>\u5468\u5185\u6216\u9884\u8ba1\u7814\u7a76\u671f\u95f4\u8fdb\u884c\u91cd\u5927\u624b\u672f\uff0c\u6216\u624b\u672f\u4f24\u53e3\u672a\u6108\u5408\u8005<\/span><\/span><\/p>\n

11  <\/span>\u6000\u5b55\u6216\u54fa\u4e73\u671f\u5973\u6027<\/span><\/span><\/p>\n

12  <\/span>\u7814\u7a76\u8005\u8ba4\u4e3a\u4e0d\u9002\u5408\u5165\u7ec4\u7684\u60a3\u8005<\/span> <\/span><\/span><\/p>\n

 <\/span><\/p>\n

6.       <\/span><\/span>\u4e3b\u8981\u7814\u7a76\u8005\u4fe1\u606f<\/span><\/span><\/p>\n

\u4e3b\u8981\u7814\u7a76\u8005\u4fe1\u606f<\/span><\/p>\n\n\n\n\n\n
\n

\u59d3\u540d <\/span><\/p>\n<\/td>\n

\n

\u6731\u519b\uff0c\u535a\u58eb <\/span><\/p>\n<\/td>\n

\n

\u804c\u79f0 <\/span><\/p>\n<\/td>\n

\n

\u4e3b\u4efb\u533b\u5e08 <\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u90ae\u653f\u5730\u5740 <\/span><\/p>\n<\/td>\n

\n

\u5317\u4eac\u5e02\u6d77\u6dc0\u533a\u961c\u6210\u8def52\u53f7 <\/span><\/p>\n<\/td>\n

\n

\u90ae\u7f16 <\/span><\/p>\n<\/td>\n

\n

100037 <\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u5355\u4f4d\u540d\u79f0 <\/span><\/p>\n<\/td>\n

\n

\u5317\u4eac\u80bf\u7624\u533b\u9662 <\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u5404\u53c2\u52a0\u673a\u6784\u4fe1\u606f<\/span><\/p>\n\n\n\n\n
\n

\u5e8f\u53f7 <\/span><\/p>\n<\/td>\n

\n

\u673a\u6784\u540d\u79f0 <\/span><\/p>\n<\/td>\n

\n

\u4e3b\u8981\u7814\u7a76\u8005 <\/span><\/p>\n<\/td>\n

\n

\u56fd\u5bb6 <\/span><\/p>\n<\/td>\n

\n

\u7701\uff08\u5dde\uff09 <\/span><\/p>\n<\/td>\n

\n

\u57ce\u5e02 <\/span><\/p>\n<\/td>\n<\/tr>\n

\n

1 <\/span><\/p>\n<\/td>\n

\n

\u4e2d\u56fd\u533b\u5b66\u79d1\u5b66\u9662\u8840\u6db2\u75c5\u533b\u9662 <\/span><\/p>\n<\/td>\n

\n

\u9f50\u519b\u5143 <\/span><\/p>\n<\/td>\n

\n

\u4e2d\u56fd <\/span><\/p>\n<\/td>\n

\n

\u5929\u6d25 <\/span><\/p>\n<\/td>\n

\n

\u5929\u6d25 <\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/span><\/p>\n

\u672c\u8bd5\u9a8c\u4fe1\u606f\u6765\u81ea<\/span>CFDA<\/span>\u201c\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u767b\u8bb0\u4e0e\u516c\u793a\u5e73\u53f0\u201d\u3002<\/span><\/span><\/p>\n

\u6b22\u8fce\u7533\u529e\u65b9\/CRO\/\u533b\u9662\u63d0\u4f9b\u80bf\u7624\u62db\u52df\u4fe1\u606f\uff0c\u53ef\u4ee5\u53d1\u90ae\u4ef6\u81f3LCSYZMXX@163.com\uff0c\u672c\u516c\u4f17\u53f7\u514d\u8d39\u63a8\u9001\u3002<\/span><\/p>\n

\n


<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

1.       \u8bd5\u9a8c\u836f\u7269\u7b80\u4ecb BAT4306F\u662f […]<\/p>\n","protected":false},"author":1,"featured_media":49442,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/49441"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=49441"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/49441\/revisions"}],"predecessor-version":[{"id":49443,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/49441\/revisions\/49443"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/49442"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=49441"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=49441"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=49441"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}