{"id":49488,"date":"2018-09-18T01:00:00","date_gmt":"2018-09-26T01:59:02","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/26\/%e4%ba%ba%e5%b7%a5%e6%99%ba%e8%83%bd20%e7%a7%92%e8%af%86%e5%88%ab%e8%82%ba%e7%99%8c-%e4%bb%a3%e7%a0%81%e5%85%ac%e5%bc%80%e4%ba%86\/"},"modified":"2018-09-26T09:59:03","modified_gmt":"2018-09-26T01:59:03","slug":"%e4%ba%ba%e5%b7%a5%e6%99%ba%e8%83%bd20%e7%a7%92%e8%af%86%e5%88%ab%e8%82%ba%e7%99%8c-%e4%bb%a3%e7%a0%81%e5%85%ac%e5%bc%80%e4%ba%86","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/49488\/","title":{"rendered":"\u4eba\u5de5\u667a\u80fd20\u79d2\u8bc6\u522b\u80ba\u764c \u4ee3\u7801\u516c\u5f00\u4e86"},"content":{"rendered":"
\n

\u75c5\u7406\u79d1\u533b\u751f\u5f80\u5f80\u9700\u8981\u81f3\u5c11\u4e00\u5206\u949f\u6765\u8bc6\u522b\u80ba\u764c\u5f71\u50cf\uff0c\u5982\u4eca\uff0c\u4e00\u4e2a\u4eba\u5de5\u667a\u80fd\u7684\u7a0b\u5e8f\u53ef\u4ee5\u572820\u79d2\u6765\u5b8c\u6210\u3002<\/span><\/p>\n


<\/p>\n

\u8fd9\u4e2a\u4eba\u5de5\u667a\u80fd\u5229\u7528\u673a\u5668\u5b66\u4e60\uff0c\u901a\u8fc7\u8bad\u7ec3\u4e00\u4e2a\u6df1\u5ea6\u79ef\u795e\u7ecf\u7f51\u7edc\uff08convolutional neural network\uff09\u6765\u5bf9\u80bf\u7624\u57fa\u56e0\u56fe\u8c31\uff08cancer genome atlas\uff09\u8fdb\u884c\u81ea\u52a8\u5206\u7c7b\u3002<\/span><\/p>\n


<\/span><\/p>\n

\u8fd9\u4e2a\u7814\u7a76\u6210\u679c\u521a\u521a\u53d1\u8868\u5728\u81ea\u7136\u533b\u836f\uff08Nature Medicine\uff09\u4e0a\u3002<\/span><\/p>\n


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\u76ee\u524d\uff0c\u80ba\u764c\u7684\u80bf\u7624\u75c5\u7406\u5207\u7247\u4ecd\u7136\u662f\u7531\u75c5\u7406\u79d1\u533b\u751f\u8fdb\u884c\u76ee\u89c6\u68c0\u67e5\uff0c\u7136\u540e\u5224\u65ad\u80bf\u7624\u5206\u671f\uff0c\u5206\u578b\uff0c\u7c7b\u522b\u548c\u4e9a\u578b\u3002<\/span><\/p>\n


<\/p>\n

\u975e\u5c0f\u7ec6\u80de\u80ba\u764c(NSCLC)\u6700\u5e38\u89c1\u7684\u4e9a\u578b\u5305\u62ec\u817a\u764c\uff08LUAD\uff09\u548c\u9cde\u764c\uff08LUSC\uff09\uff0c\u9700\u8981\u7531\u7ecf\u9a8c\u4e30\u5bcc\u7684\u75c5\u7406\u5b66\u5bb6\u6765\u8fdb\u884c\u76ee\u89c6\u68c0\u67e5\u3002<\/span><\/p>\n


<\/p>\n

\u5982\u4eca\uff0c\u6709\u4e86\u4eba\u5de5\u667a\u80fd\u7684\u5e2e\u52a9\uff0c\u8fd9\u4e2a\u7a0b\u5e8f\u53ef\u4ee5\u81ea\u52a8\u5206\u522b\u817a\u764c\uff0c\u9cde\u764c\u548c\u826f\u6027\u80ba\u7ed3\u8282\u3002\u800c\u4e14\uff0c\u7a0b\u5e8f\u7684\u4ee3\u7801\u662f\u5f00\u6e90\u7684\u4ee3\u7801\u3002<\/span><\/p>\n

\"\u4eba\u5de5\u667a\u80fd20\u79d2\u8bc6\u522b\u80ba\u764c<\/p>\n

\uff08\u53d1\u8868\u5728Nature Medicine\u7684\u4eba\u5de5\u667a\u80fd\u8bc6\u522b\u80ba\u764c\u7684\u6587\u7ae0<\/span><\/em>\uff09
<\/p>\n


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\u5728\u4e00\u4e2a340\u4e2a\u7684\u60a3\u8005\u56fe\u50cf\u8bc6\u522b\u4e2d, \u8fd9\u4e2a\u7a0b\u5e8f\u6b63\u786e\u533a\u5206\u4e86\u8fd9\u4e24\u4e2a\u80ba\u764c\u80bf\u7624\u5206\u578b\uff0c\u5176\u4e2d, \u771f\u9633\u6027\u4e0e\u5047\u9633\u6027\u7684\u533a\u57df\u4e0b\u7684\u66f2\u7ebf (area under the curve) \u4e3a0.861-0. 977<\/span>\u3002<\/span><\/p>\n


<\/p>\n

\u6b64\u5916\uff0c\u8fd9\u4e2a\u7a0b\u5e8f\u8bad\u7ec3\u80fd\u9884\u6d4b10\u79cd\u6700\u5e38\u89c1\u7684\u80ba\u764c\u57fa\u56e0\u7a81\u53d8\u4e2d\u7684\u516d\u79cd\u57fa\u56e0\u7a81\u53d8\u3002TA\u4eec\u662f\uff1aSTK11, EGFR\uff08\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\uff09\uff0cFAT1\uff0cSETBP1\uff0cKRAS\u548cTP53\uff0c\u90fd\u53ef\u4ee5\u901a\u8fc7\u75c5\u7406\u56fe\u50cf\u9884\u6d4b\u3002<\/span><\/p>\n


<\/p>\n

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<\/p>\n

\u66f4\u4ee4\u4eba\u60ca\u559c\u7684\u662f\uff0c\u8be5\u7b97\u6cd5\u53ef\u4ee5\u68c0\u6d4b\u67d0\u4e9b\u7a81\u53d8\u5f15\u8d77\u7684\u7ec4\u7ec7\u5f62\u6001\u5b66\u53d8\u5316<\/span>\uff0c\u4f5c\u8005\u5efa\u8bae\u3002<\/span><\/p>\n


<\/p>\n

 \u201c\u8fd9\u4e2a\u7a0b\u5e8f\u8868\u660e\uff0c\u4eba\u5de5\u667a\u80fd\u53ef\u80fd\u5e2e\u52a9\u75c5\u7406\u79d1\u533b\u751f\u8bc6\u522b\u80bf\u7624\u5206\u578b\u548c\u57fa\u56e0\u7a81\u53d8\u7c7b\u578b\uff0c\u800c\u4e14\uff0c<\/span>\u6211\u4eec\u7684\u8fd9\u4e2a\u7a0b\u5e8f\u53ef\u4ee5\u7528\u4e8e\u4efb\u4f55\u80bf\u7624\u7c7b\u578b<\/span>\uff0c\u201d\u4f5c\u8005\u8868\u793a\u3002<\/span><\/p>\n


<\/p>\n

\u6587\u7ae0\u7684\u4e3b\u8981\u4f5c\u8005\uff0c\u7ebd\u7ea6\u5927\u5b66\u7684\u52a9\u7406\u6559\u6388Aristotelis Tsirigos\u544a\u8bc9\u751f\u7269\u4e16\u7eaa\uff0c\u4e0b\u4e00\u6b65\u8ba1\u5212\u662f\u901a\u8fc7\u4f7f\u7528\u66f4\u591a\u7684\u56fe\u50cf\u6765\u8bad\u7ec3\u7b97\u6cd5\uff0c\u5305\u62ec\u4ece\u75c5\u7406\u5b66\u5bb6\u5f97\u5230\u66f4\u8be6\u7ec6\u6ce8\u89e3\u7684\u56fe\u50cf\uff0c\u6765\u63d0\u9ad8\u7b97\u6cd5\u7684\u51c6\u786e\u6027\u3002Tsirigos \u662f\u7ebd\u7ea6\u5927\u5b66\u5e94\u7528\u751f\u7269\u4fe1\u606f\u5b66\u5b9e\u9a8c\u5ba4\u4e3b\u4efb\u3002<\/span><\/p>\n


<\/p>\n

\u8fd9\u4e2a\u4ee3\u7801\u53ef\u4ee5\u5728Github\u627e\u5230\u3002\u5730\u5740\u662f<\/span>https:\/\/github.com\/ncoudray\/DeepPATH<\/span><\/span>.<\/span><\/span><\/p>\n


<\/p>\n

Nature Medicine\u7f51\u5740\uff1a<\/span><\/p>\n

https:\/\/www.nature.com\/articles\/s41591-018-0177-5<\/span><\/p>\n


<\/strong><\/span><\/p>\n

\u751f\u7269\u4e16\u7eaa\u62a5\u9053\uff1a<\/strong><\/span><\/p>\n

https:\/\/www.biocentury.com\/bc-extra\/tools-techniques\/2018-09-17\/ai-code-could-speed-cancer-diagnosis-treatment-decisions-0<\/span><\/p>\n

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\u4f60\u53ef\u80fd\u559c\u6b22<\/strong>\uff1a<\/span><\/p>\n

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<\/p>\n

\u6d88\u5316\u80bf\u7624\u836f\u6548\u4e0d\u4f73\uff1f\u65e5\u672c\u8981\u6ef4\u8840\u67e573\u57fa\u56e0<\/span><\/a>
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\u670d\u52a1\u65b0\u836f\u7814\u53d1 \u628a\u63e1\u6295\u8d44\u8d8b\u52bf<\/span><\/em><\/span><\/p>\n

\u6bcf\u5929\u7528\u65b0\u8bf4\u8bdd \u51b3\u7b56\u4e0d\u53ef\u6216\u7f3a<\/span><\/em><\/span><\/p>\n

\u5065\u70b9\u5b50ihealth<\/em><\/strong>\u662f\u533b\u836f\u884c\u4e1a\u9886\u5148\u7684\u6295\u8d44\u987e\u95ee\u8d44\u8baf\u5e73\u53f0\uff0c\u4e13\u6ce8<\/em>\u7f55\u89c1\u75c5\uff0c<\/strong>\u751f\u7269\u7c7b\u4f3c\u836f\uff0c<\/strong><\/em>\u65e5\u97e9\u5370\u5ea6<\/strong><\/em>\u5065\u5eb7\u884c\u4e1a\u7684\u6700\u65b0\u52a8\u5411\u3002<\/em><\/span><\/p>\n

\u4f60\u4e5f\u53ef\u4ee5\u5728\u4efb\u4f55\u5065\u70b9\u5b50\u6587\u7ae0\u540e\u7559\u8a00\u3002\u8bf7\u7b80\u77ed\u8bf4\u660e\u5177\u4f53\u9700\u6c42\u3002\u6211\u4eec\u4e00\u822c\u572824\u5c0f\u65f6\u4e4b\u5185\u8054\u7cfb\u3002<\/em><\/span><\/p>\n

<\/em><\/em><\/em><\/span><\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

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