{"id":50208,"date":"2018-09-18T01:00:00","date_gmt":"2018-09-26T02:06:34","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/26\/%e7%a7%91%e5%ad%a6%e5%ae%b6%e8%a7%a3%e6%9e%90%e4%b8%80%e7%a7%8d%e5%9f%ba%e5%9b%a0%e5%8f%98%e5%bc%82%e7%9a%84%e8%87%b4%e7%99%8c%e9%a3%8e%e9%99%a9\/"},"modified":"2018-09-26T10:06:35","modified_gmt":"2018-09-26T02:06:35","slug":"%e7%a7%91%e5%ad%a6%e5%ae%b6%e8%a7%a3%e6%9e%90%e4%b8%80%e7%a7%8d%e5%9f%ba%e5%9b%a0%e5%8f%98%e5%bc%82%e7%9a%84%e8%87%b4%e7%99%8c%e9%a3%8e%e9%99%a9","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/50208\/","title":{"rendered":"\u79d1\u5b66\u5bb6\u89e3\u6790\u4e00\u79cd\u57fa\u56e0\u53d8\u5f02\u7684\u81f4\u764c\u98ce\u9669"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"text-align: center;\"><img class=\"\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/8-1537927595.jpeg\" alt=\"\u79d1\u5b66\u5bb6\u89e3\u6790\u4e00\u79cd\u57fa\u56e0\u53d8\u5f02\u7684\u81f4\u764c\u98ce\u9669\" title=\"\u79d1\u5b66\u5bb6\u89e3\u6790\u4e00\u79cd\u57fa\u56e0\u53d8\u5f02\u7684\u81f4\u764c\u98ce\u9669\"  \/><\/p>\n<p style=\"font-family: \u5b8b\u4f53;font-size: 14px;white-space: normal;background-color: rgb(248, 249, 244);text-indent: 2em;\"><span style=\"font-size: 16px;\">\u300a\u81ea\u7136\u300b\u8fd1\u65e5\u5728\u7ebf\u53d1\u8868\u7684\u4e00\u7bc7\u8bba\u6587\u5bf9\u6570\u5343\u79cdBRCA1\u7684\u57fa\u56e0\u53d8\u5f02\u6309\u529f\u80fd\u8fdb\u884c\u4e86\u66f4\u7cbe\u786e\u7684\u5206\u7c7b\u3002\u8fd9\u4e9b\u529f\u80fd\u8bc4\u5206\u5bf9\u4e73\u817a\u764c\u548c\u5375\u5de2\u764c\u7f79\u60a3\u98ce\u9669\u7684\u57fa\u56e0\u68c0\u6d4b\u89e3\u8bfb\u6216\u5177\u6709\u4e34\u5e8a\u610f\u4e49\u3002<\/span><\/p>\n<p style=\"text-align: left;\"><img class=\"\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/2-1537927595.jpeg\" alt=\"\u79d1\u5b66\u5bb6\u89e3\u6790\u4e00\u79cd\u57fa\u56e0\u53d8\u5f02\u7684\u81f4\u764c\u98ce\u9669\" title=\"\u79d1\u5b66\u5bb6\u89e3\u6790\u4e00\u79cd\u57fa\u56e0\u53d8\u5f02\u7684\u81f4\u764c\u98ce\u9669\"  \/><\/p>\n<p style=\"font-family: \u5b8b\u4f53;font-size: 14px;white-space: normal;background-color: rgb(248, 249, 244);text-indent: 2em;\"><span style=\"font-size: 16px;\">BRCA1\u662f\u4e00\u79cd\u4eba\u4f53\u80bf\u7624\u6291\u5236\u57fa\u56e0\uff0cBRCA1\u5931\u53bb\u529f\u80fd\u7684\u7a81\u53d8\u4e0e\u6613\u60a3\u65e9\u53d1\u578b\u4e73\u817a\u764c\u548c\u5375\u5de2\u764c\u6709\u5173\u3002\u867d\u7136\u5df2\u53d1\u73b0\u7684BRCA1\u57fa\u56e0\u53d8\u5f02\u6709\u6570\u5343\u79cd\uff0c\u4f46\u8bb8\u591a\u90fd\u88ab\u5217\u4e3a\u201c\u610f\u4e49\u672a\u660e\u7684\u53d8\u5f02\u201d\uff0c\u7ed9\u60a3\u764c\u98ce\u9669\u8bc4\u4f30\u5e26\u6765\u4e86\u5de8\u5927\u6311\u6218\u3002<\/span><\/p>\n<p style=\"font-family: \u5b8b\u4f53;font-size: 14px;white-space: normal;background-color: rgb(248, 249, 244);text-indent: 2em;\"><span style=\"font-size: 16px;\">\u8981\u5f04\u6e05\u8fd9\u4e9b\u610f\u4e49\u672a\u660e\u7684\u53d8\u5f02\uff0c\u5176\u4e2d\u4e00\u4e2a\u65b9\u6cd5\u662f\u68c0\u6d4b\u53d8\u5f02\u57fa\u56e0\u7684\u8868\u8fbe\u662f\u5426\u5177\u6709\u6062\u590dDNA\u4fee\u590d\u7684\u529f\u80fd\uff0c\u8fd9\u4e5f\u662f\u80bf\u7624\u6291\u5236\u8fc7\u7a0b\u7684\u4e00\u90e8\u5206\u3002\u7f8e\u56fd\u534e\u76db\u987f\u5927\u5b66\u7684Jay Shendure\u53ca\u540c\u4e8b\u8fd0\u7528\u57fa\u56e0\u7ec4\u7f16\u8f91\u6280\u672f\uff0c\u5bf9BRCA1\u57fa\u56e0\u529f\u80fd\u81f3\u5173\u91cd\u8981\u768413\u4e2a\u5916\u663e\u5b50\u4e0a\u7684\u8fd14000\u79cd\u5355\u6838\u82f7\u9178\u53d8\u5f02\uff08SNV\uff09\u7684\u529f\u80fd\u8fdb\u884c\u4e86\u8bc4\u4f30\uff0c\u5e76\u57282000\u4e07\u4e2a\u4eba\u7c7b\u5355\u500d\u4f53\uff08HAP1\uff09\u7ec6\u80de\u4e2d\u8fdb\u884c\u4e86\u540e\u7eed\u7ec6\u80de\u5b58\u6d3b\u7387\u6d4b\u5b9a\u3002<\/span><\/p>\n<p style=\"font-family: \u5b8b\u4f53;font-size: 14px;white-space: normal;background-color: rgb(248, 249, 244);text-indent: 2em;\"><span style=\"font-size: 16px;\">\u6700\u540e\uff0c\u7814\u7a76\u4eba\u5458\u8bc6\u522b\u51fa\u4e86\u7ea6300\u79cd\u4f1a\u5e72\u6270\u8868\u8fbe\u7684SNV\u4ee5\u53ca400\u591a\u79cd\u9519\u4e49\u7a81\u53d8\u7684SNV\uff08\u4f1a\u5bfc\u81f4\u86cb\u767d\u8d28\u7684\u6c28\u57fa\u9178\u5e8f\u5217\u6539\u53d8\uff09\uff0c\u53d1\u73b0\u8fd9\u4e9b\u53d8\u5f02\u5e76\u65e0\u5b9e\u9645\u529f\u80fd\uff08\u4e0d\u7834\u574f\u57fa\u56e0\u7684\u539f\u6709\u529f\u80fd\uff09\u3002\u8fd9\u4e9b\u529f\u80fd\u8bc4\u5206\u4e0e\u5df2\u77e5\u7684\u81f4\u75c5\u6027\u53d8\u5f02\u6216\u826f\u6027\u53d8\u5f02\u7684\u4e34\u5e8a\u8bc4\u4f30\u5bc6\u5207\u76f8\u5173\u3002<\/span><\/p>\n<p style=\"font-family: \u5b8b\u4f53;font-size: 14px;white-space: normal;background-color: rgb(248, 249, 244);text-indent: 2em;\"><span style=\"font-size: 16px;\">\u8be5\u56e2\u961f\u6307\u51fa\uff0c\u4e0e\u5176\u4ed6\u7ec6\u80de\u7cfb\u76f8\u6bd4\uff0cHAP1\u7ec6\u80de\u7cfb\u53ef\u80fd\u4e0d\u662f\u751f\u7406\u5b66\u4e0a\u7684\u6700\u4f18\u6a21\u578b\uff0c\u4f46\u4e0e\u4e34\u5e8a\u8bc4\u4f30\u7684\u9ad8\u5ea6\u76f8\u5173\u6027\u9a8c\u8bc1\u4e86\u6570\u636e\u3002\u7814\u7a76\u8005\u80af\u5b9a\u4e86\u529f\u80fd\u8bc4\u5206\u5bf9\u53d8\u5f02\u5206\u7c7b\u7684\u91cd\u8981\u4ef7\u503c\uff0c\u5e76\u8ba4\u4e3a\u7814\u7a76\u7ed3\u679c\u53ef\u76f4\u63a5\u5e94\u7528\u4e8eBRCA1\u57fa\u56e0\u7b5b\u67e5\u7684\u89e3\u8bfb\u3002<\/span><\/p>\n<p style=\"text-align: left;\">\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u300a\u81ea\u7136\u300b\u8fd1\u65e5\u5728\u7ebf\u53d1\u8868\u7684\u4e00\u7bc7\u8bba\u6587\u5bf9\u6570\u5343\u79cdBRCA1\u7684\u57fa\u56e0\u53d8\u5f02\u6309\u529f\u80fd\u8fdb\u884c\u4e86\u66f4\u7cbe\u786e\u7684\u5206\u7c7b\u3002\u8fd9\u4e9b\u529f\u80fd\u8bc4\u5206\u5bf9\u4e73\u817a\u764c\u548c\u5375\u5de2 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":50209,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/50208"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=50208"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/50208\/revisions"}],"predecessor-version":[{"id":50212,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/50208\/revisions\/50212"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/50209"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=50208"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=50208"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=50208"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}