{"id":50359,"date":"2018-09-23T01:00:00","date_gmt":"2018-09-26T02:08:26","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/26\/keytruda%e5%ae%9a%e4%bb%b7%e5%87%ba%e7%82%89%e3%80%81%e8%af%ba%e5%a5%96%e9%a3%8e%e5%90%91%e6%a0%87%e5%bc%95%e6%96%87%e6%a1%82%e5%86%a0%e5%a5%96%e5%85%ac%e5%b8%83-bioweek\/"},"modified":"2018-09-26T10:08:30","modified_gmt":"2018-09-26T02:08:30","slug":"keytruda%e5%ae%9a%e4%bb%b7%e5%87%ba%e7%82%89%e3%80%81%e8%af%ba%e5%a5%96%e9%a3%8e%e5%90%91%e6%a0%87%e5%bc%95%e6%96%87%e6%a1%82%e5%86%a0%e5%a5%96%e5%85%ac%e5%b8%83-bioweek","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/50359\/","title":{"rendered":"Keytruda\u5b9a\u4ef7\u51fa\u7089\u3001\u201c\u8bfa\u5956\u98ce\u5411\u6807\u201d\u5f15\u6587\u6842\u51a0\u5956\u516c\u5e03\u2026| BioWeek"},"content":{"rendered":"
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\u672c\u5468\uff0c\u4e09\u7bc7NEJM\u9f50\u53d1\uff01\u6bcf\u65e5\u4f4e\u5242\u91cf\u670d\u7528\u963f\u53f8\u5339\u6797\u4e0d\u4f1a\u5ef6\u957f\u5bff\u547d\uff1bNature\u63ed\u793a\u80a0\u9053\u83cc\u80fd\u591f\u201c\u53d1\u7535\u201d\u7684\u79d8\u5bc6\u6280\u80fd\uff1b\u767e\u4e07\u79d1\u6280\u5927\u5956\u53c8\u6765\u4e86\uff01\u6768\u632f\u5b81\u3001\u65bd\u4e00\u516c\u7b49\u51fa\u5e2d\uff0c\u591a\u4f4d\u9876\u5c16\u79d1\u5b66\u5bb6\u83b7\u5956\uff1b\u57fa\u56e0\u7597\u6cd5\u6e05\u9664\u5e15\u91d1\u68ee\u81f4\u75c5\u86cb\u767d\u6307\u65e5\u53ef\u5f85\uff1b\u7ed9\u533b\u7597\u5668\u68b0\u201c\u89e3\u7ed1\u201d\uff01\u8bba\u6ce8\u518c\u4eba\u5236\u5ea6\u7684\u6539\u9769\u7ed9\u56fd\u4ea7\u5316\u5668\u68b0\u7684\u65b0\u673a\u9047\uff1bNature\u6700\u65b0\u6210\u679c\uff01\u89c4\u907fCRISPR\u7684\u201c\u8131\u9776\u6548\u5e94\u201d\uff0c\u5173\u952e\u5728\u5f15\u5bfcRNA\u2026\u2026\u66f4\u591a\u8d44\u8baf\uff0c\u8bf7\u8ddf\u968f\u5c0f\u7f16\u4e00\u8d77\u56de\u987e\u5427\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\"Keytruda\u5b9a\u4ef7\u51fa\u7089\u3001\u201c\u8bfa\u5956\u98ce\u5411\u6807\u201d\u5f15\u6587\u6842\u51a0\u5956\u516c\u5e03\u2026|<\/p>\n


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2018\u5e74\u5ea6\u201c\u5f15\u6587\u6842\u51a0\u5956\u201d\u516c\u5e03\uff0c17\u4f4d\u79d1\u5b66\u5bb6\u5165\u9009\u8bfa\u8d1d\u5c14\u5956\u9884\u6d4b\u540d\u5355<\/span><\/strong><\/a><\/p>\n


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2018\u5e749\u670820\u65e5\uff0c\u4e3a\u52a0\u901f\u79d1\u5b66\u53d1\u73b0\u548c\u521b\u65b0\uff0c\u63d0\u4f9b\u9ad8\u8d28\u91cf\u6570\u636e\u53ca\u5206\u6790\u670d\u52a1\u7684\u5168\u7403\u9886\u5bfc\u8005\u79d1\u777f\u552f\u5b89\uff08Clarivate Analytics\uff09\u5ba3\u5e03\u4e86\u51762018\u5e74\u5ea6\u201c \u5f15\u6587\u6842\u51a0\u5956\u201d\u5f97\u4e3b\uff0c17\u4f4d\u6765\u81ea\u7f8e\u56fd\u3001\u6b27\u76df\u548c\u4e9a\u6d32\u7684\u79d1\u7814\u7cbe\u82f1\u5165\u9009\u3002\u88ab\u8a89\u4e3a\u201c\u8bfa\u5956\u98ce\u5411\u6807\u201d\u7684\u79d1\u777f\u552f\u5b89\u201c\u5f15\u6587\u6842\u51a0\u5956\u201d\u81ea2002\u5e74\u9996\u5ea6\u9881\u5e03\u81f3\u4eca\uff0c\u5df2\u6709\u517146\u4f4d\u8be5\u5956\u9879\u5f97\u4e3b\u8363\u81ba\u8bfa\u8d1d\u5c14\u5956\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\"Keytruda\u5b9a\u4ef7\u51fa\u7089\u3001\u201c\u8bfa\u5956\u98ce\u5411\u6807\u201d\u5f15\u6587\u6842\u51a0\u5956\u516c\u5e03\u2026|<\/p>\n


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\u544a\u522b\u6d77\u5916\u8d2d\u836f\uff01\u4e07\u80fd\u6297\u764c\u836fKeytruda\u5b9a\u4ef7\u51fa\u7089\uff0c\u5e74\u8d39\u752816\u4e07\uff0c\u5168\u7403\u6700\u4f4e<\/span><\/strong><\/a><\/p>\n


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\u7ee7\u4eca\u5e747\u670825\u65e5\u6b63\u5f0f\u8fdb\u5165\u5927\u9646\u5e02\u573a\u4e4b\u540e\uff0c\u4e00\u6b21\u83b7\u627915\u79cd\u80bf\u7624\u9002\u5e94\u75c7\u7684\u6297\u764c\u795e\u836fKeytruda\uff08K\u836f\uff0c\u5546\u54c1\u540d\u53ef\u745e\u8fbe\uff09\u5b9a\u4ef7\u8fd1\u65e5\u6b63\u5f0f\u51fa\u7089\uff1a\u4e2d\u56fd\u96f6\u552e\u4ef7\u4e3a17918\u5143\/100mg\uff0c\u5168\u5e74\u6cbb\u7597\u8d39\u7528\u4e3a304606\u5143\uff1b\u5bf9\u4e8e\u4f4e\u6536\u5165\u60a3\u8005\uff0c\u901a\u8fc7PAP\u8ba1\u5212\u8d60\u836f\u653f\u7b56\u4e3a3+3\uff08\u4e703\u4e2a\u7597\u7a0b\u90013\u4e2a\u7597\u7a0b\uff09\uff0c\u60a3\u8005\u9700\u8d1f\u62c5\u7684\u5e74\u6cbb\u7597\u8d39\u7528\u6700\u4f4e\u4e3a161262\u5143\uff1b\u800c\u5bf9\u4e8e\u4f4e\u4fdd\u60a3\u8005\uff0c\u53ef\u4ee5\u514d\u8d39\u4f7f\u752824\u4e2a\u6708\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\"Keytruda\u5b9a\u4ef7\u51fa\u7089\u3001\u201c\u8bfa\u5956\u98ce\u5411\u6807\u201d\u5f15\u6587\u6842\u51a0\u5956\u516c\u5e03\u2026|<\/p>\n


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\u533b\u7597\u5668\u68b0\u6ce8\u518c\u4eba\u5236\u5ea6\u904d\u5730\u5f00\u82b1\uff01\u6c5f\u82cf\u53d1\u5e03\u9f13\u52b1\u836f\u54c1\u5668\u68b0\u521b\u65b0\u5b9e\u65bd\u610f\u89c1<\/span><\/strong><\/a><\/span><\/strong><\/span><\/strong><\/p>\n


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\u201c\u533b\u7597\u5668\u68b0\u6ce8\u518c\u4eba\u5236\u5ea6\u201d\u8fd9\u4e00\u533b\u7597\u5668\u68b0\u884c\u4e1a\u7684\u98a0\u8986\u6027\u6539\u9769\uff0c\u6700\u65e9\u5728\u4e0a\u6d77\u8bd5\u70b9\uff0c\u540e\u6269\u5927\u5230\u5929\u6d25\u3001\u5e7f\u4e1c\u4e24\u5730\u30029\u670812\u65e5\uff0c\u4e2d\u5171\u6c5f\u82cf\u7701\u59d4\u529e\u516c\u5385\u53d1\u5e03\u300a\u5173\u4e8e\u6df1\u5316\u5ba1\u8bc4\u5ba1\u6279\u5236\u5ea6\u6539\u9769\u9f13\u52b1\u836f\u54c1\u533b\u7597\u5668\u68b0\u521b\u65b0\u7684\u5b9e\u65bd\u610f\u89c1\u300b\uff0c\u533b\u7597\u5668\u68b0\u6ce8\u518c\u4eba\u5236\u5ea6\u89e6\u624b\u53ef\u53ca\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\"Keytruda\u5b9a\u4ef7\u51fa\u7089\u3001\u201c\u8bfa\u5956\u98ce\u5411\u6807\u201d\u5f15\u6587\u6842\u51a0\u5956\u516c\u5e03\u2026|<\/p>\n


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\u4eab\u53d7\u6539\u9769\u7ea2\u5229\uff01\u5e7f\u4e1c\u7701\u98df\u836f\u5c40\u6b63\u5f0f\u6210\u7acb\u533b\u7597\u5668\u68b0\u6ce8\u518c\u4eba\u5236\u5ea6\u8bd5\u70b9\u5de5\u4f5c\u7ec4<\/span><\/strong><\/a><\/p>\n


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\u201c\u533b\u7597\u5668\u68b0\u6ce8\u518c\u4eba\u5236\u5ea6\u201d\u8fd9\u4e00\u533b\u7597\u5668\u68b0\u884c\u4e1a\u7684\u98a0\u8986\u6027\u6539\u9769\uff0c\u81ea\u5728\u4e0a\u6d77\u8bd5\u70b9\u4ee5\u6765\uff0c\u4f17\u591a\u533b\u7597\u5668\u68b0\u521b\u65b0\u4f01\u4e1a\u7eb7\u7eb7\u53d7\u76ca\u4e8e\u6b64\u3002\u4e3a\u4e86\u8ba9\u66f4\u591a\u7684\u4f01\u4e1a\u4eab\u53d7\u6539\u9769\u7ea2\u5229\uff0c2018\u5e748\u670816\u65e5\uff0c\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u540c\u610f\u5e7f\u4e1c\u7701\u8bd5\u70b9\u201c\u533b\u7597\u5668\u68b0\u6ce8\u518c\u4eba\u5236\u5ea6\u201d\uff0c\u6807\u5fd7\u7740\u5373\u65e5\u8d77\u5e7f\u4e1c\u7701 \u201c\u533b\u7597\u5668\u68b0\u6ce8\u518c\u4eba\u5236\u5ea6\u201d\u6b63\u5f0f\u843d\u5730\u5b9e\u65bd\u30029\u670814\u65e5\uff0c\u5e7f\u4e1c\u7701\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u4e0b\u53d1\u4e86\u5173\u4e8e\u6210\u7acb\u63a8\u8fdb\u8fd9\u4e00\u5236\u5ea6\u7684\u8bd5\u70b9\u5de5\u4f5c\u4e13\u8d23\u5de5\u4f5c\u7ec4\u7684\u901a\u77e5\uff0c\u786e\u4fdd\u533b\u7597\u5668\u68b0\u6ce8\u518c\u4eba\u5236\u5ea6\u7684\u987a\u5229\u63a8\u8fdb\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\"Keytruda\u5b9a\u4ef7\u51fa\u7089\u3001\u201c\u8bfa\u5956\u98ce\u5411\u6807\u201d\u5f15\u6587\u6842\u51a0\u5956\u516c\u5e03\u2026|<\/p>\n


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\u767e\u4e07\u79d1\u6280\u5927\u5956\u53c8\u6765\u4e86\uff01\u6768\u632f\u5b81\u3001\u65bd\u4e00\u516c\u7b49\u51fa\u5e2d\uff0c\u591a\u4f4d\u9876\u5c16\u79d1\u5b66\u5bb6\u83b7\u5956<\/span><\/span><\/strong><\/a><\/span><\/strong><\/span><\/strong><\/p>\n


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2018\u5e74\u5ea6\u6c42\u662f\u5956\u9881\u5956\u5178\u793c15\u65e5\u665a\u5728\u4e2d\u56fd\u79d1\u5b66\u6280\u672f\u5927\u5b66\u4e3e\u884c\u3002\u4e2d\u79d1\u9662\u7406\u5316\u6280\u672f\u7814\u7a76\u6240\u6c5f\u96f7\u6559\u6388\u83b72018\u5e74\u5ea6\u201c\u6c42\u662f\u6770\u51fa\u79d1\u5b66\u5bb6\u5956\u201d\u30022018\u5e74\u5ea6\u201c\u6c42\u662f\u79d1\u6280\u6210\u5c31\u96c6\u4f53\u5956\u201d\u5219\u6388\u4e88\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66\u5f20\u6770\u6559\u6388\u9886\u5bfc\u7684\u6fc0\u5149\u5f3a\u573a\u7269\u7406\u56e2\u961f\u3002\u4e24\u8005\u5206\u522b\u83b7\u5f97\u5956\u91d1\u4eba\u6c11\u5e01\u4e00\u767e\u4e07\u5143\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\"Keytruda\u5b9a\u4ef7\u51fa\u7089\u3001\u201c\u8bfa\u5956\u98ce\u5411\u6807\u201d\u5f15\u6587\u6842\u51a0\u5956\u516c\u5e03\u2026|<\/p>\n


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\u80e1\u76db\u5bff\u9662\u58eb\uff1a\u667a\u6167\u533b\u7597\u2014\u2014\u79bb\u6211\u4eec\u5f88\u8fd1\uff0c\u4e5f\u5f88\u8fdc<\/span><\/strong><\/a><\/p>\n


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\u201c\u667a\u6167\u533b\u7597\uff0c\u79bb\u6211\u4eec\u5f88\u8fd1\uff0c\u4e5f\u5f88\u8fdc\u3002\u201d\u8fd9\u662f\u4e2d\u56fd\u5de5\u7a0b\u9662\u9662\u58eb\u3001\u56fd\u5bb6\u5fc3\u8111\u8840\u7ba1\u75c5\u4e2d\u5fc3\u4e3b\u4efb\u3001\u4e2d\u56fd\u533b\u5b66\u79d1\u5b66\u9662\u57e0\u5916\u533b\u9662\u9662\u957f\u80e1\u76db\u5bff\u57289\u670820\u65e5\u4e3e\u884c\u76842018\u6df1\u5733\u56fd\u9645BT\u9886\u8896\u5cf0\u4f1a\u4e0a\u63d0\u51fa\u7684\u5bf9\u4eba\u5de5\u667a\u80fd\u7684\u601d\u8003\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\"Keytruda\u5b9a\u4ef7\u51fa\u7089\u3001\u201c\u8bfa\u5956\u98ce\u5411\u6807\u201d\u5f15\u6587\u6842\u51a0\u5956\u516c\u5e03\u2026|<\/p>\n


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\u4e09\u7bc7NEJM\u9f50\u53d1\uff01\u6bcf\u65e5\u4f4e\u5242\u91cf\u670d\u7528\u963f\u53f8\u5339\u6797\uff0c\u5e76\u4e0d\u4f1a\u5ef6\u957f\u5bff\u547d<\/span><\/strong><\/a><\/span><\/strong><\/span><\/strong><\/p>\n


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\u4e4b\u524d\u300a\u67f3\u53f6\u5200\u300b\u53d1\u6587\u79f0\uff0c\u201c\u795e\u836f\u201d\u963f\u53f8\u5339\u6797\u5728\u9884\u9632\u5fc3\u810f\u75c5\u548c\u4e2d\u98ce\u4e0a\u5e76\u6ca1\u6709\u201c\u5b9a\u8bba\u201d\u3002\u73b0\u5728\uff0c\u300aNew England Journal of Medicine\u300b\u671f\u520a\u540c\u6837\u201c\u8c28\u614e\u201d\u8868\u6001\uff1a\u5bf9\u4e8e\u5065\u5eb7\u7684\u8001\u5e74\u4eba\uff08\u65e0\u5fc3\u8840\u7ba1\u75be\u75c5\uff09\uff0c\u6bcf\u5929\u670d\u7528\u4f4e\u5242\u91cf\u963f\u53f8\u5339\u6797\u5e76\u4e0d\u4f1a\u5ef6\u957f\u5bff\u547d\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\"Keytruda\u5b9a\u4ef7\u51fa\u7089\u3001\u201c\u8bfa\u5956\u98ce\u5411\u6807\u201d\u5f15\u6587\u6842\u51a0\u5956\u516c\u5e03\u2026|<\/p>\n


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\u65b0\u5947\uff01Nature\u63ed\u793a\u80a0\u9053\u83cc\u80fd\u591f\u201c\u53d1\u7535\u201d\u7684\u79d8\u5bc6\u6280\u80fd<\/span><\/strong><\/span><\/a><\/span><\/strong><\/span><\/strong><\/p>\n


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\u79d1\u5b66\u5bb6\u4eec\u66fe\u53d1\u73b0\uff0c\u53ea\u6709\u5728\u50cf\u77ff\u4e95\u548c\u6e56\u5e95\u7b49\u7279\u5f02\u73af\u5883\u4e2d\uff0c\u4e00\u4e9b\u7ec6\u83cc\u624d\u80fd\u4ea7\u751f\u7535\u80fd\u3002\u4f46\u8fd1\u65e5\uff0c\u52a0\u5dde\u5927\u5b66\u4f2f\u514b\u5229\u5206\u6821\u7684\u7814\u7a76\u4eba\u5458\u60ca\u8bb6\u5730\u53d1\u73b0\uff0c\u5355\u6838\u7ec6\u80de\u589e\u751f\u674e\u65af\u7279\u83cc\u7b49\u80a0\u9053\u83cc\u7adf\u7136\u4e5f\u80fd\u201c\u53d1\u7535\u201d\uff01\u8fd9\u4e00\u53d1\u73b0\u4e3a\u5c06\u6765\u6b32\u7814\u7a76\u5fae\u751f\u7269\u53d1\u7535\u6280\u672f\u7684\u79d1\u5b66\u5bb6\u5e26\u53bb\u4e86\u6781\u5927\u9f13\u821e\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\"Keytruda\u5b9a\u4ef7\u51fa\u7089\u3001\u201c\u8bfa\u5956\u98ce\u5411\u6807\u201d\u5f15\u6587\u6842\u51a0\u5956\u516c\u5e03\u2026|<\/p>\n


<\/strong><\/span><\/p>\n

Nature\u6700\u65b0\u6210\u679c\uff01\u89c4\u907fCRISPR\u7684\u201c\u8131\u9776\u6548\u5e94\u201d\uff0c\u5173\u952e\u5728\u5f15\u5bfcRNA<\/span><\/strong><\/a><\/span><\/strong><\/span><\/strong><\/p>\n


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\u4f5c\u4e3a\u6700\u53d7\u5173\u6ce8\u7684\u57fa\u56e0\u7f16\u8f91\u795e\u5668\uff0cCRISPR\u6280\u672f\u7684\u4e34\u5e8a\u4ef7\u503c\u4e00\u76f4\u6709\u5f85\u843d\u5b9e\u3002\u4f46\u662f\uff0c\u8fd9\u4e00\u98a0\u8986\u6027\u6280\u672f\u7684\u201c\u8131\u9776\u6548\u5e94\u201d\u4e00\u76f4\u662f\u963b\u788d\u5176\u5e94\u7528\u7684\u5173\u952e\u969c\u788d\u4e4b\u4e00\u3002\u8fd1\u65e5\uff0c\u79d1\u5b66\u5bb6\u4eec\u627e\u5230\u4e86\u4e00\u79cd\u9884\u6d4bCRISPR\u51c6\u786e\u6027\u7684\u65b9\u6cd5\uff0c\u80fd\u591f\u6709\u6548\u9650\u5236\u5176\u9519\u8bef\u7f16\u8f91\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\"Keytruda\u5b9a\u4ef7\u51fa\u7089\u3001\u201c\u8bfa\u5956\u98ce\u5411\u6807\u201d\u5f15\u6587\u6842\u51a0\u5956\u516c\u5e03\u2026|<\/p>\n


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\u65e9\u7b5b\u6096\u8bba\uff01\u56fd\u9645\u764c\u75c7\u6742\u5fd7\u8bc1\u660e\uff0c\u4e73\u817a\u764c\u7b5b\u67e5\u4e0d\u80fd\u964d\u4f4e\u6b7b\u4ea1\u7387<\/span><\/strong><\/span><\/a><\/span><\/strong><\/span><\/strong><\/p>\n


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\u6765\u81ea\u4e39\u9ea6\u548c\u632a\u5a01\u7684\u4e00\u9879\u7814\u7a76\u8868\u660e\uff0c\u8fd1\u5e74\u6765\u6b7b\u4e8e\u4e73\u817a\u764c\u7684\u5973\u6027\u8d8a\u6765\u8d8a\u5c11\uff0c\u4f46\u4ee4\u4eba\u60ca\u8bb6\u7684\u662f\uff0c\u5728\u672a\u63a5\u53d7\u7b5b\u67e5\u7684\u5e74\u9f84\u7ec4\u4e2d\uff0c\u8fd9\u4e00\u4e0b\u964d\u5e45\u5ea6\u4e5f\u540c\u6837\u5927\u3002\u56e0\u6b64\uff0c\u6b7b\u4ea1\u7387\u7684\u4e0b\u964d\u662f\u7531\u4e8e\u66f4\u597d\u7684\u6cbb\u7597\uff0c\u800c\u975e\u4e73\u817a\u764c\u7b5b\u67e5\uff0c\u5373\u4e73\u817a\u764c\u7b5b\u67e5\u5e76\u4e0d\u80fd\u964d\u4f4e\u60a3\u8005\u6b7b\u4ea1\u7387\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\"Keytruda\u5b9a\u4ef7\u51fa\u7089\u3001\u201c\u8bfa\u5956\u98ce\u5411\u6807\u201d\u5f15\u6587\u6842\u51a0\u5956\u516c\u5e03\u2026|<\/p>\n


<\/strong><\/span><\/p>\n

\u53c8\u4e00\u8fdb\u6b65\uff01\u57fa\u56e0\u7597\u6cd5\u6e05\u9664\u5e15\u91d1\u68ee\u81f4\u75c5\u86cb\u767d\u6307\u65e5\u53ef\u5f85<\/span><\/strong><\/a><\/p>\n


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\u5e15\u91d1\u68ee\u75c5\u662f\u4e00\u79cd\u6162\u6027\u8fdb\u884c\u6027\u8fd0\u52a8\u969c\u788d\uff0c\u5f71\u54cd\u8eab\u4f53\u63a7\u5236\u8fd0\u52a8\u7684\u80fd\u529b\uff0c\u76ee\u524d\u5c1a\u65e0\u6709\u6548\u6cbb\u7597\u65b9\u6cd5\u3002\u8fd1\u65e5\uff0c\u7531\u62c9\u4ec0\u533b\u5b66\u9662(Rush Medical College)\u7684\u7814\u7a76\u4eba\u5458 Jeffrey Kordower\u535a\u58eb\u9886\u5bfc\u7684\u4e00\u4e2a\u56fd\u9645\u5c0f\u7ec4\u5728\u5e15\u91d1\u68ee\u6cbb\u7597\u4e2d\u8fc8\u51fa\u91cd\u8981\u4e00\u6b65\uff1a\u5229\u7528\u57fa\u56e0\u7597\u6cd5\u6e05\u9664\u81f4\u75c5\u86cb\u767d\uff01<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\"Keytruda\u5b9a\u4ef7\u51fa\u7089\u3001\u201c\u8bfa\u5956\u98ce\u5411\u6807\u201d\u5f15\u6587\u6842\u51a0\u5956\u516c\u5e03\u2026|<\/p>\n


<\/strong><\/span><\/p>\n

Nature\uff1a\u80bf\u7624\u5fae\u73af\u5883\u51b3\u5b9a\u809d\u764c\u7c7b\u578b<\/span><\/strong><\/a><\/span><\/strong><\/span><\/strong><\/p>\n


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\u80bf\u7624\u5468\u56f4\u7684\u7ec4\u7ec7\u3001\u514d\u75ab\u7ec6\u80de\u3001\u8840\u7ba1\u3001\u7ec6\u80de\u5916\u57fa\u8d28\u7b49\u5143\u7d20\u5171\u540c\u5f62\u6210\u4e86\u201c\u80bf\u7624\u5fae\u73af\u5883\u201d\uff0c\u540e\u8005\u662f\u534f\u52a9\u80bf\u7624\u66f4\u5feb\u6269\u589e\u3001\u5165\u4fb5\u7684\u201c\u80a5\u6c83\u571f\u58e4\u201d\u3002\u73b0\u5728\uff0c\u4e00\u9879\u6700\u65b0\u7814\u7a76\u8868\u660e\uff0c\u80bf\u7624\u5fae\u73af\u5883\u8fd8\u4f1a\u51b3\u5b9a\u809d\u764c\u7c7b\u578b\uff01<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\"Keytruda\u5b9a\u4ef7\u51fa\u7089\u3001\u201c\u8bfa\u5956\u98ce\u5411\u6807\u201d\u5f15\u6587\u6842\u51a0\u5956\u516c\u5e03\u2026|<\/p>\n


<\/strong><\/span><\/p>\n

\u9996\u4e2a\uff01\u7eb3\u7c73\u6280\u672f\u4ecb\u5165\u6291\u764c\u57fa\u56e0\u5728\u524d\u5217\u817a\u764c\u4e2d\u53d6\u5f97\u7a81\u7834\u8fdb\u5c55 | Nature\u5b50\u520a<\/span><\/span><\/strong><\/a><\/span><\/strong><\/span><\/strong><\/p>\n


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\u4f17\u6240\u5468\u77e5\uff0c\u6291\u764c\u57fa\u56e0PTEN\u548cP53\u7b49\u7684\u7a81\u53d8\u548c\u7f3a\u5931\u4f1a\u5bfc\u81f4\u764c\u75c7\u4e0d\u53d7\u6291\u5236\u5730\u751f\u957f\u3002\u9488\u5bf9\u76f8\u5173\u57fa\u56e0\u7a81\u53d8\u7684\u7814\u7a76\u6709\u5f88\u591a\uff0c\u800c\u9488\u5bf9\u764c\u75c7\u4e2d\u4e22\u5931\u7684\u86cb\u767d\u8d28\u7684\u7814\u7a76\u4e00\u76f4\u662f\u4e00\u4e2a\u6311\u6218\u3002\u8fd1\u65e5\uff0c\u603b\u90e8\u4f4d\u4e8e\u6ce2\u58eb\u987f\u7684\u4e00\u4e2a\u5408\u4f5c\u56e2\u961f\u5229\u7528\u7eb3\u7c73\u6280\u672f\u548c\u72ec\u7279\u7684mRNA\u7279\u6027\uff0c\u901a\u8fc7\u9776\u5411PTEN\u6291\u5236\u4e86\u524d\u5217\u817a\u764c\u4e34\u5e8a\u524d\u6a21\u578b\u4e2d\u7684\u80bf\u7624\u751f\u957f\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u672c\u6587\u7cfb\u751f\u7269\u63a2\u7d22\u539f\u521b\uff0c\u6b22\u8fce\u4e2a\u4eba\u8f6c\u53d1\u5206\u4eab\u3002\u5176\u4ed6\u4efb\u4f55\u5a92\u4f53\u3001\u7f51\u7ad9\u5982\u9700\u8f6c\u8f7d\uff0c\u987b\u5728\u6b63\u6587\u524d\u6ce8\u660e\u6765\u6e90\u751f\u7269\u63a2\u7d22\u3002<\/span><\/p>\n<\/section>\n

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\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

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