{"id":50972,"date":"2018-09-25T01:00:00","date_gmt":"2018-09-26T02:14:04","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/26\/%e5%b9%b2%e8%b4%a7-%e6%ae%8b%e7%95%99%e6%ba%b6%e5%89%82%e6%96%b9%e6%b3%95%e5%bb%ba%e7%ab%8b%e5%8f%8a%e6%96%b9%e6%b3%95%e5%ad%a6%e7%9a%84%e9%aa%8c%e8%af%81\/"},"modified":"2018-09-26T10:14:05","modified_gmt":"2018-09-26T02:14:05","slug":"%e5%b9%b2%e8%b4%a7-%e6%ae%8b%e7%95%99%e6%ba%b6%e5%89%82%e6%96%b9%e6%b3%95%e5%bb%ba%e7%ab%8b%e5%8f%8a%e6%96%b9%e6%b3%95%e5%ad%a6%e7%9a%84%e9%aa%8c%e8%af%81","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/50972\/","title":{"rendered":"\u5e72\u8d27 | \u6b8b\u7559\u6eb6\u5242\u65b9\u6cd5\u5efa\u7acb\u53ca\u65b9\u6cd5\u5b66\u7684\u9a8c\u8bc1"},"content":{"rendered":"
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\u836f\u7269\u4e2d\u7684\u6b8b\u7559\u6eb6\u5242\u7cfb\u6307\u5728\u539f\u6599\u836f\u6216\u8f85\u6599\u7684\u751f\u4ea7\u4e2d\u3001\u4ee5\u53ca\u5728\u5236\u5242\u5236\u5907\u8fc7\u7a0b\u4e2d\u4f7f\u7528\u6216\u4ea7\u751f\u800c\u53c8\u672a\u80fd\u5b8c\u5168\u53bb\u9664\u7684\u6709\u673a\u6eb6\u5242\u3002\u6839\u636e\u6709\u673a\u6eb6\u5242\u5bf9\u4eba\u4f53\u53ca\u73af\u5883\u53ef\u80fd\u9020\u6210\u7684\u5371\u5bb3\u7684\u7a0b\u5ea6\uff0c ICH\u5c06\u6709\u673a\u6eb6\u5242\u5206\u4e3a\u907f\u514d\u4f7f\u7528\u3001\u9650\u5236\u4f7f\u7528\u3001\u4f4e\u6bd2\u548c\u6bd2\u6027\u4f9d\u636e\u5c1a\u4e0d\u8db3\u56db\u79cd\u60c5\u51b5\u3002\u56e0\u6b8b\u7559\u6eb6\u5242\u4f1a\u5f71\u54cd\u4ea7\u54c1\u7684\u5b89\u5168\u6027\uff0c\u6545\u9700\u5bf9\u5176\u8fdb\u884c\u7814\u7a76\u3002<\/span><\/p>\n


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\u4e8c<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u7814\u7a76\u65b9\u6cd5\u7684\u5efa\u7acb\u53ca\u65b9\u6cd5\u5b66\u9a8c\u8bc1<\/section>\n<\/section>\n
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\u5728\u786e\u5b9a\u4e86\u9700\u8981\u8fdb\u884c\u6b8b\u7559\u91cf\u7814\u7a76\u7684\u6eb6\u5242\u540e\uff0c\u9700\u8981\u901a\u8fc7\u65b9\u6cd5\u5b66\u7814\u7a76\u5efa\u7acb\u5408\u7406\u53ef\u884c\u7684\u68c0\u6d4b\u65b9\u6cd5\u3002\u76ee\u524d\uff0c\u6b8b\u7559\u6eb6\u5242\u7684\u6d4b\u5b9a\u4e00\u822c\u91c7\u7528\u6c14\u76f8\u8272\u8c31\u6cd5\uff0c\u63a8\u8350\u4f7f\u7528\u6bdb\u7ec6\u7ba1\u8272\u8c31\u67f1-  \u9876\u7a7a\u8fdb\u6837\u7cfb\u7edf\uff0c\u5f53\u7136\u4e5f\u53ef\u4ee5\u4f7f\u7528\u666e\u901a\u586b\u5145\u67f1\uff0c\u6eb6\u6db2\u76f4\u63a5\u8fdb\u6837\u65b9\u6cd5\u3002\u5bf9\u4e0d\u5b9c\u91c7\u7528\u6c14\u76f8\u8272\u8c31\u6cd5\u6d4b\u5b9a\u7684\u542b\u6c2e\u78b1\u6027\u5316\u5408\u7269\uff0c\u5982N- \u7532\u57fa\u5421\u54af\u70f7\u916e\u7b49\u53ef\u91c7\u7528\u5176\u5b83\u65b9\u6cd5\uff0c\u5982\u79bb\u5b50\u8272\u8c31\u6cd5\u7b49\u3002<\/span><\/p>\n

GC\u6cd5\u5177\u6709\u68c0\u6d4b\u7075\u654f\u5ea6\u8f83\u9ad8\uff0c\u9009\u62e9\u6027\u8f83\u597d\u7684\u7279\u70b9\uff0c\u91c7\u7528\u6b64\u6cd5\u6240\u9700\u7684\u6837\u54c1\u7528\u91cf\u8f83\u5c11\uff0c\u57fa\u672c\u53ef\u4ee5\u6ee1\u8db3\u6240\u6709\u6b8b\u7559\u6eb6\u5242\u6d4b\u5b9a\u7684\u8981\u6c42\u3002\u91c7\u7528GC\u6cd5\u65f6\uff0c\u9700\u8981\u7ed3\u5408\u836f\u7269\u548c\u6240\u8981\u68c0\u6d4b\u7684\u6eb6\u5242\u7684\u6027\u8d28\uff0c\u901a\u8fc7\u65b9\u6cd5\u5b66\u7814\u7a76\u786e\u5b9a\u5408\u9002\u7684\u68c0\u6d4b\u6761\u4ef6\u3002<\/span><\/p>\n

1 \u7814\u7a76\u65b9\u6cd5\u7684\u5efa\u7acb<\/span><\/strong><\/span><\/p>\n

1.1 \u786e\u5b9a\u88ab\u6d4b\u7684\u6709\u673a\u6eb6\u5242<\/span><\/strong><\/p>\n

\u6839\u636e\u5236\u5907\u5de5\u827a\u786e\u5b9a\u88ab\u6d4b\u6709\u673a\u6eb6\u5242\u7684\u8303\u56f4\u3002\u901a\u5e38\u5e94\u5bf9\u5236\u5907\u5de5\u827a\u8fc7\u7a0b\u4e2d\u4f7f\u7528\u7684\u4e8c\u7c7b\u4ee5\u4e0a\u6eb6\u5242\u548c\u91cd\u7ed3\u6676\u7528\u6eb6\u5242\uff0c\u4ee5\u53ca\u6839\u636e\u5de5\u827a\u7279\u70b9\u8981\u6c42\u7684\u5176\u5b83\u6eb6\u5242\u8fdb\u884c\u6b8b\u7559\u91cf\u7684\u7814\u7a76\u3002\u5efa\u8bae\u5bf9\u5408\u6210\u6700\u540e\u4e09\u6b65\u4f7f\u7528\u7684\u4e09\u7c7b\u6eb6\u5242\u4e5f\u8fdb\u884c\u7814\u7a76\uff0c\u8fd9\u6837\u80fd\u66f4\u597d\u5730\u5bf9\u672a\u77e5\u5cf0\u8fdb\u884c\u5f52\u5c5e\uff1b\u5bf9\u5236\u5242\u8fc7\u7a0b\u4e2d\u4f7f\u7528\u7684\u6709\u673a\u6eb6\u5242\u4e5f\u5efa\u8bae\u8003\u5bdf\u5176\u6b8b\u7559\u60c5\u51b5\uff0c\u7279\u522b\u662f\u7f13\u3001\u63a7\u91ca\u5fae\u4e38\u5305\u8863\u8fc7\u7a0b\u4f7f\u7528\u7684\u6709\u673a\u6eb6\u5242\u66f4\u5e94\u5f15\u8d77\u6ce8\u610f\u3002<\/span><\/p>\n

1.2 \u8272\u8c31\u67f1\u9009\u62e9<\/span><\/strong><\/p>\n

 \u6309\u7167\u76f8\u4f3c\u76f8\u6eb6\u7684\u539f\u7406\u9009\u62e9\u8272\u8c31\u67f1\u3002\u6bdb\u7ec6\u7ba1\u67f1\u6709\u6781\u6027\u67f1\u3001\u975e\u6781\u6027\u67f1\u3001\u5f31\u6781\u6027\u67f1\u548c\u4e2d\u7b49\u6781\u6027\u67f1\u3002\u586b\u5145\u67f1\u6709\u9ad8\u5206\u5b50\u591a\u5b54\u5c0f\u7403\u6216\u6d82\u6e0d\u9002\u5b9c\u56fa\u5b9a\u6db2\u7684\u586b\u5145\u67f1\u3002\u6d4b\u5b9a\u542b\u6c2e\u7684\u78b1\u6027\u6709\u673a\u6eb6\u5242\u65f6\uff0c\u7531\u4e8e\u666e\u901a\u6c14\u76f8\u8272\u8c31\u4eea\u7684\u4e0d\u9508\u94a2\u7ba1\u8def\u3001\u8fdb\u6837\u5668\u886c\u7ba1\u7b49\u5bf9\u6709\u673a\u80fa\u7b49\u542b\u6c2e\u7684\u78b1\u6027\u5316\u5408\u7269\u5177\u6709\u8f83\u5f3a\u7684\u5438\u9644\u4f5c\u7528\uff0c\u81f4\u4f7f\u5176\u68c0\u51fa\u7684\u7075\u654f\u5ea6\u964d\u4f4e\u3002\u901a\u5e38\u91c7\u7528\u5f31\u6781\u6027\u8272\u8c31\u67f1\u6216\u7ecf\u78b1\u5904\u7406\u8fc7\u7684\u8272\u8c31\u67f1\u5206\u6790\u542b\u6c2e\u7684\u78b1\u6027\u6709\u673a\u6eb6\u5242\uff0c\u5982\u679c\u91c7\u7528\u80fa\u5206\u6790\u4e13\u7528\u67f1\u8fdb\u884c\u5206\u6790\uff0c\u5219\u6548\u679c\u66f4\u597d\u3002<\/span><\/p>\n

1.3 \u8fdb\u6837\u65b9\u6cd5<\/span><\/strong><\/p>\n

GC \u6cd5\u5305\u62ec\u6eb6\u6db2\u76f4\u63a5\u8fdb\u6837\u548c\u9876\u7a7a\u8fdb\u6837\u4e24\u79cd\u8fdb\u6837\u65b9\u6cd5\u3002\u901a\u5e38\u60c5\u51b5\u4e0b\uff0c\u6cb8\u70b9\u4f4e\u7684\u6eb6\u5242\u5efa\u8bae\u91c7\u7528\u9876\u7a7a\u8fdb\u6837\u6cd5\uff0c\u6cb8\u70b9\u9ad8\u7684\u6eb6\u5242\u53ef\u4ee5\u91c7\u7528\u6eb6\u6db2\u76f4\u63a5\u8fdb\u6837\u6cd5\uff0c\u5f53\u6837\u54c1\u672c\u8eab\u5bf9\u6d4b\u5b9a\u6709\u5f71\u54cd\u65f6\uff0c\u4e5f\u5efa\u8bae\u91c7\u7528\u9876\u7a7a\u8fdb\u6837\u6cd5\u3002<\/span><\/p>\n

1.4 \u4f9b\u8bd5\u54c1\u6eb6\u6db2\u548c\u5bf9\u7167\u54c1\u6eb6\u6db2\u7684\u914d\u5236<\/span><\/strong><\/p>\n

\u5bf9\u4e8e\u56fa\u4f53\u539f\u6599\u836f\uff0c\u5982\u91c7\u7528\u6eb6\u6db2\u76f4\u63a5\u8fdb\u6837\u6cd5\uff0c\u9700\u5148\u7528\u6c34\u6216\u5408\u9002\u7684\u6eb6\u5242\u4f7f\u539f\u6599\u836f\u6eb6\u89e3\uff0c\u4ee5\u4f7f\u5176\u4e2d\u7684\u6709\u673a\u6eb6\u5242\u91ca\u653e\u4e8e\u6eb6\u6db2\u4e2d\uff0c\u624d\u80fd\u88ab\u51c6\u786e\u6d4b\u5b9a\u3002\u5982\u91c7\u7528\u9876\u7a7a\u8fdb\u6837\u6cd5\uff0c\u901a\u5e38\u4ee5\u6c34\u4f5c\u6eb6\u5242\uff1b\u5f53\u836f\u7269\u4e0d\u6eb6\u4e8e\u6c34\uff0c\u4f46\u53ef\u6eb6\u4e8e\u4e00\u5b9a\u6d53\u5ea6\u7684\u9178\u6216\u78b1\u6db2\u4e2d\u65f6\uff0c\u53ef\u91c7\u7528\u4e0d\u6325\u53d1\u7684\u9178\u6216\u78b1\u6db2\u4e3a\u6eb6\u5242\uff0c\u4f46\u4e0d<\/span>\u80fd\u4f7f\u7528\u76d0\u9178\u6eb6\u6db2\u6216\u6c28\u6c34\uff1b\u5bf9\u4e8e\u975e\u6c34\u6eb6\u6027\u836f\u7269\uff0c\u53ef\u91c7\u7528\u5408\u9002\u7684\u6eb6\u5242,\u5982N,N\u2014\u4e8c\u7532\u57fa\u7532\u9170\u80fa\u3001\u4e8c\u7532\u57fa\u4e9a\u781c\u7b49\u4e3a\u6eb6\u5242\u3002\u4ee5DMSO  \u7b49\u4e3a\u6eb6\u5242\u65f6\uff0c\u53ef\u52a0\u5165\u4e00\u5b9a\u91cf\u7684\u6c34\u4ee5\u589e\u52a0\u68c0\u6d4b\u7684\u7075\u654f\u5ea6\uff0c\u6216\u7528\u76d0\u6790\u7684\u65b9\u6cd5\u589e\u52a0\u7075\u654f\u5ea6\u3002<\/span><\/span><\/p>\n

1.5 \u4f9b\u8bd5\u54c1\u6eb6\u6db2\u548c\u5bf9\u7167\u54c1\u6eb6\u6db2\u6d53\u5ea6\u7684\u786e\u5b9a<\/span><\/strong><\/p>\n

\u914d\u5236\u4f9b\u8bd5\u54c1\u6eb6\u6db2\u7684\u6d53\u5ea6\u5e94\u6ee1\u8db3\u5b9a\u91cf\u6d4b\u5b9a\u7684\u9700\u8981\uff0c\u4e00\u822c\u4f9b\u8bd5\u54c1\u53d6\u6837\u91cf\u57280.1 ~1g\u4e4b\u95f4\u3002\u9650\u5ea6\u68c0\u67e5\u65f6\u5bf9\u7167\u54c1\u6eb6\u6db2\u7684\u6d53\u5ea6\u53ef\u6309\u89c4\u5b9a\u7684\u9650\u5ea6\u914d\u5236\uff0c\u5b9a\u91cf\u6d4b\u5b9a\u65f6\u6309\u5b9e\u9645\u6b8b\u7559\u91cf\u914d\u5236\uff0c\u6d53\u5ea6\u76f8\u5dee\u6700\u597d\u4ee5\u4e0d\u8d85\u8fc7 2  \u500d\u4e3a\u5b9c\u3002<\/span><\/p>\n

1.6 \u68c0\u6d4b\u5668\u7684\u9009\u62e9<\/span><\/strong><\/p>\n

\u4e00\u822c\u9009\u7528FID\u68c0\u6d4b\u5668\uff0c\u5bf9\u542b\u5364\u7d20\u7684\u6709\u673a\u6eb6\u5242\u5982\u6c2f\u4eff\u7b49\uff0c\u91c7\u7528  ECD\u68c0\u6d4b\u5668\u53ef\u5f97\u5230\u66f4\u9ad8\u7684\u7075\u654f\u5ea6\u3002\u901a\u5e38\u53ef\u6839\u636e\u836f\u7269\u6eb6\u5242\u7684\u6b8b\u7559\u60c5\u51b5\u9009\u62e9\u5408\u9002\u7684\u68c0\u67e5\u65b9\u6cd5\u3002\u5f53\u9700\u8981\u68c0\u67e5\u7684\u6709\u673a\u6eb6\u5242\u6570\u91cf\u4e0d\u591a\uff0c\u4e14\u6781\u6027\u5dee\u5f02\u8f83\u5c0f\u65f6\uff0c\u53ef\u9009\u62e9\u6bdb\u7ec6\u7ba1\u8272\u8c31\u67f1 –  \u9876\u7a7a\u8fdb\u6837-\u7b49\u6e29\u6cd5\u3002\u5f53\u9700\u8981\u68c0\u67e5\u7684\u6709\u673a\u6eb6\u5242\u6570\u91cf\u8f83\u591a\uff0c\u4e14\u6781\u6027\u3001\u6cb8\u70b9\u5dee\u5f02\u8f83\u5927\u65f6\uff0c\u53ef\u9009\u62e9\u6bdb\u7ec6\u7ba1\u8272\u8c31\u67f1  -\u9876\u7a7a\u8fdb\u6837-  \u7a0b\u5e8f\u5347\u6e29\u6cd5\uff1b\u4e5f\u53ef\u9009\u62e9\u586b\u5145\u67f1\u6216\u9002\u5b9c\u6781\u6027\u7684\u6bdb\u7ec6\u7ba1\u67f1\u76f4\u63a5\u8fdb\u6837\u6cd5\u3002<\/span><\/p>\n

1.7 \u9876\u7a7a\u8fdb\u6837\u6cd5\u8fd8\u8981\u5bf9\u9876\u7a7a\u6e29\u5ea6\u548c\u9876\u7a7a\u65f6\u95f4\u8fdb\u884c\u9009\u62e9<\/span><\/strong><\/p>\n

\u9876\u7a7a\u6e29\u5ea6\u5e94\u6839\u636e\u6eb6\u89e3\u4f9b\u8bd5\u54c1\u6eb6\u5242\u7684\u7279\u6027\u53ca\u4f9b\u8bd5\u54c1\u4e2d\u6b8b\u7559\u6eb6\u5242\u7684\u6cb8\u70b9\u9009\u62e9\u3002\u4ee5\u6c34\u4e3a\u6eb6\u5242\u53ca\u6d4b\u5b9a\u4f4e\u6cb8\u70b9\u6b8b\u7559\u6eb6\u5242\u65f6\uff0c\u9876\u7a7a\u6e29\u5ea6\u4e0d\u5b9c\u8d85\u8fc785 \u2103\uff1b\u6d4b\u5b9a\u6cb8\u70b9\u8f83\u9ad8\u7684\u6b8b\u7559\u6eb6\u5242\u65f6\uff0c\u901a\u5e38\u9009\u62e9\u8f83\u9ad8\u7684\u9876\u7a7a\u6e29\u5ea6\uff1b\u4f46\u6b64\u65f6\u5e94\u517c\u987e\u4f9b\u8bd5\u54c1\u7684\u70ed\u5206\u89e3\u7279\u6027\uff0c\u5c3d\u91cf\u907f\u514d\u4f9b\u8bd5\u54c1\u4ea7\u751f\u7684\u6325\u53d1\u6027\u70ed\u5206\u89e3\u4ea7\u7269\u5e72\u6270\u6d4b\u5b9a\u7ed3\u679c\u3002\u4ee5  DMSO\u4e3a\u6eb6\u5242\u65f6\uff0c\u9876\u7a7a\u6e29\u5ea6\u4e0d\u5b9c\u8d85\u8fc7115  \u2103\u3002\u4f8b\u5982\uff0c\u5728\u7533\u62a5\u8d44\u6599\u4e2d\u53d1\u73b0\uff0c\u4ee5\u6c34\u4e3a\u6eb6\u5242\uff0c\u9876\u7a7a\u6e29\u5ea6\u4e3a100 \u2103\uff0c\u67f1\u6e29  60\u2103\uff0c\u7ed3\u679c\u9ad8\u6d53\u5ea6\u7684\u4e59\u8148\u6bd4\u4f4e\u6d53\u5ea6\u7684\u4e8c\u6c2f\u7532\u70f7\u7684\u5cf0\u9762\u79ef\u8fd8\u5c0f\uff0c\u539f\u56e0\u662f\u9876\u7a7a\u6e29\u5ea6\u592a\u9ad8\uff0c\u5927\u91cf\u7684\u6c34\u88ab\u84b8\u53d1\uff08\u6216\u6d53\u5ea6\u88ab\u7a00\u91ca\uff09\uff0c\u968f\u7740\u6c34\u84b8\u6c7d\u7684\u51dd\u7ed3\uff0c\u5728\u6c34\u4e2d\u6eb6\u89e3\u5ea6\u5927\u7684\u4e59\u8148\u7684\u7075\u654f\u5ea6\u4e0b\u964d\uff0c\u4ea7\u751f\u4e86\u4e0e\u4e8b\u5b9e\u4e0d\u7b26\u7684\u5b9e\u9a8c\u7ed3\u679c\u3002<\/span><\/p>\n

\u9876\u7a7a\u65f6\u95f4\u662f\u8981\u786e\u4fdd\u4f9b\u8bd5\u54c1\u6eb6\u6db2\u7684\u6c14-\u6db2\u4e24\u76f8\u8fbe\u5230\u5e73\u8861\uff0c\u4e00\u822c\u901a\u8fc7\u6d4b\u5b9a\u9876\u7a7a\u65f6\u95f4\u4e0e\u9876\u7a7a\u6c14\u4f53\u6d53\u5ea6\u7684\u6d53\u5ea6  \u2014\u65f6\u95f4\u66f2\u7ebf\u6765\u786e\u5b9a\u3002\u9876\u7a7a\u65f6\u95f4\u4e0d\u5b9c\u8fc7\u957f\uff0c\u4e00\u822c\u4e3a30~45\u5206\u949f\uff0c\u5982\u679c\u8d85\u8fc7  60min \uff0c\u53ef\u80fd\u5f15\u8d77\u9876\u7a7a\u74f6\u7684\u6c14\u5bc6\u6027\u53d8\u5dee, \u5bfc\u81f4\u5b9a\u91cf\u7684\u51c6\u786e\u6027\u964d\u4f4e\u3002\u5982\u679c\u5e73\u8861\u65f6\u95f4\u9009\u62e9 10\u5206\u949f\uff0c\u5c31\u4e0d\u80fd\u4fdd\u8bc1\u6c14- \u6db2\u4e24\u76f8\u8fbe\u5230\u5e73\u8861\u3002\u5bf9\u7167\u54c1\u6eb6\u6db2\u4e0e\u4f9b\u8bd5\u54c1\u6eb6\u6db2\u5fc5\u987b\u4f7f\u7528\u76f8\u540c\u7684\u9876\u7a7a\u6761\u4ef6\u3002<\/span><\/p>\n


<\/p>\n

\n

\"\u5e72\u8d27<\/p>\n<\/section>\n


<\/p>\n


<\/p>\n

2\u3001\u65b9\u6cd5\u5b66\u9a8c\u8bc1<\/span><\/strong><\/span><\/p>\n

2.1\u7cfb\u7edf\u9002\u7528\u6027\u8bd5\u9a8c<\/span><\/strong><\/p>\n

\u67f1\u6548\uff1a\u7528\u88ab\u6d4b\u7269\u7684\u8272\u8c31\u5cf0\u8ba1\u7b97\uff0c\u586b\u5145\u67f1\u6cd5\u7684\u7406\u8bba\u677f\u6570\u5e94\u5927\u4e8e1000 \uff0c\u6bdb\u7ec6\u7ba1\u8272\u8c31\u67f1\u7684\u7406\u8bba\u677f\u6570\u5e94\u5927\u4e8e  5000\u3002<\/span><\/p>\n

\u5206\u79bb\u5ea6\uff1a\u8272\u8c31\u56fe\u4e2d\u88ab\u6d4b\u7269\u8272\u8c31\u5cf0\u4e0e\u5176\u76f8\u90bb\u8272\u8c31\u5cf0\u7684\u5206\u79bb\u5ea6\u5e94\u5927\u4e8e1.5  \u3002<\/span><\/p>\n

 \u91cd\u590d\u6027\uff1a\u4ee5\u5185\u6807\u6cd5\u6d4b\u5b9a\u65f6\uff0c\u5bf9\u7167\u54c1\u6eb6\u6db2\u8fde\u7eed\u8fdb\u68375\u6b21\uff0c\u6240\u5f97\u88ab\u6d4b\u7269\u4e0e\u5185\u6807\u7269\u5cf0\u9762\u79ef\u4e4b\u6bd4\u7684\u76f8\u5bf9\u6807\u51c6\u504f\u5dee (RSD)\u5e94\u4e0d\u5927\u4e8e5%  \uff1b\u4ee5\u5916\u6807\u6cd5\u6d4b\u5b9a\u65f6\uff0c\u6240\u5f97\u88ab\u6d4b\u7269\u5cf0\u9762\u79ef\u7684\u76f8\u5bf9\u6807\u51c6\u504f\u5dee (RSD)\u5e94\u4e0d\u5927\u4e8e 10% \u3002<\/span><\/p>\n

2.2<\/span><\/strong>\u4e13<\/span><\/strong>\u5c5e\u6027<\/span><\/strong><\/p>\n

\u5bf9\u5404\u79cd\u6b8b\u7559\u6eb6\u5242\u5b9a\u4f4d\u548c\u8fdb\u884c\u6df7\u5408\u6eb6\u5242\u7684\u5206\u79bb\u5ea6\u8bd5\u9a8c\uff0c\u5206\u79bb\u5ea6\u5e94\u5927\u4e8e1. 5 \u3002\u540c\u65f6\u7a7a\u767d\u6eb6\u5242\u5bf9\u88ab\u6d4b\u6eb6\u5242\u65e0\u5e72\u6270\u3002<\/span><\/p>\n

2.3\u7ebf\u6027<\/span><\/strong><\/p>\n

\u81f3\u5c11\u5236\u59076\u4e2a\u6d53\u5ea6\uff08\u5982\u5b9a\u9650\uff0c10%\uff0c20%\uff0c40%\uff0c60%\uff0c80%\uff0c100%\uff0c120%\u6b8b\u7559\u6eb6\u5242\u9650\u5ea6\u6c34\u5e73\uff09\uff0c\u76f8\u5173\u7cfb\u6570\u4e0d\u5c0f\u4e8e0.99\u3002<\/span><\/p>\n

2.4\u68c0\u6d4b\u9650\u548c\u5b9a\u91cf\u9650<\/span><\/strong><\/p>\n

\u68c0\u6d4b\u9650\u4e3a\u4fe1\u566a\u6bd43\uff5e5\u65f6\u76f8\u5e94\u6d53\u5ea6\u6216\u6ce8\u5165\u4eea\u5668\u7684\u91cf\u3002\u5b9a\u91cf\u6d4b\u5b9a\u65f6\u9700\u9a8c\u8bc1\u5b9a\u91cf\u9650\uff0c\u5176\u9650\u5ea6\u4e3a\u4fe1\u566a\u6bd410\uff5e15\u65f6\u76f8\u5e94\u6d53\u5ea6\u6216\u6ce8\u5165\u4eea\u5668\u7684\u91cf\u3002\u5b9a\u91cf\u9650\u5e94\u4e0d\u9ad8\u4e8e\u6b8b\u7559\u6eb6\u5242\u9650\u5ea6\u768450%\u3002<\/span><\/p>\n

2.5\u7cbe\u5bc6\u5ea6<\/span><\/strong><\/p>\n

2.5.1\u91cd\u590d\u6027<\/span><\/p>\n

\u8fde\u7eed\u8fdb\u68376\u6b21\uff0c\u6807\u51c6\u6eb6\u6db2\u5cf0\u9762\u79efRSD\u4e0d\u5f97\u5927\u4e8e10%\u3002<\/span><\/p>\n

2.5.2\u4e2d\u95f4\u7cbe\u5bc6\u5ea6<\/span><\/p>\n

\u4e0d\u540c\u65f6\u95f4\uff0c\u4e0d\u540c\u5b9e\u9a8c\u4eba\u5458\uff0c\u4e0d\u540c\u4eea\u5668\uff0c\u6d4b\u5f97\u7684\u4f9b\u8bd5\u54c1\u6eb6\u6db2\u4e2d\u6b8b\u7559\u6eb6\u5242\u7684\u5cf0\u9762\u79efRSD\u4e0d\u5f97\u5927\u4e8e10%\u3002<\/span><\/p>\n

2.6\u51c6\u786e\u5ea6<\/span><\/strong><\/p>\n

\u5728\u89c4\u5b9a\u7684\u8303\u56f4\u5185\uff0c\u81f3\u5c119\u4e2a\u6d4b\u5b9a\u7ed3\u679c\u3002\u8bbe\u8ba1\u4e09\u4e2a\u4e0d\u540c\u7684\u6d53\u5ea6\uff08\u4e00\u822c\u52a0\u516580%\uff0c100%\uff0c120%\u4e09\u4e2a\u4e0d\u540c\u9650\u5ea6\u6d53\u5ea6\u7684\u6807\u51c6\u6eb6\u6db2\uff09\u8fdb\u884c\u6d4b\u5b9a\uff0c\u8ba1\u7b97\u56de\u6536\u7387\u548c\u76f8\u5bf9\u6807\u51c6\u504f\u5dee\uff0c\u56de\u6536\u7387\u5e94\u572880%\uff5e120%\uff0c\u5404\u6d53\u5ea6\u6c34\u5e73\u56de\u6536\u7387\u7684RSD\u5e94\u4e0d\u5927\u4e8e2.0%\u3002<\/span><\/p>\n

2.7\u8010\u7528\u6027<\/span><\/strong><\/p>\n

\u901a\u8fc7\u6539\u53d8\u67f1\u6d41\u901f\uff0c\u521d\u59cb\u67f1\u6e29\uff0c\u8272\u8c31\u67f1\u578b\u53f7\u7b49\uff0c\u8003\u5bdf\u8272\u8c31\u53c2\u6570\u7684\u5fae\u5c0f\u53d8\u5316\u5bf9\u7ed3\u679c\u7684\u5f71\u54cd\u3002\u6765\u6e90\uff1a\u836f\u667a\u5708<\/span><\/span><\/p>\n

\n
\n
<\/section>\n<\/section>\n<\/section>\n


<\/p>\n

\n
\n
\n
\n
\n
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\u8fd1\u671f\u57f9\u8bad\u70b9\u51fb\u53f3\u4fa7\u4f1a\u8bae\u94fe\u63a5\u5373\u53ef\u9605\u8bfb\u539f\u6587 <\/span>  <\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\n
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\n\n\n\n\n<\/colgroup>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u5730\u70b9<\/span><\/th>\n\u65f6\u95f4<\/span><\/th>\n\u4f1a\u8bae\u94fe\u63a5<\/span><\/th>\n<\/tr>\n
\u9f50\u9f50\u54c8\u5c14<\/span><\/strong><\/span><\/td>\n9\u670827-29\u65e5<\/span><\/td>\n\u9f50\u9f50\u54c8\u5c14\u4e3e\u529e2018\u4e2d\u56fd\u5927\u5065\u5eb7\u80cc\u666f\u4e0b\u4e2d\u836f\u7c7b\u5065\u5eb7\u4ea7\u54c1\u5f00\u53d1\u4e0e\u521b\u65b0\u53ca\u4e2d\u836f\u8d44\u6e90\u7efc\u5408\u5229\u7528\u9ad8\u5cf0\u8bba\u575b<\/span><\/span><\/a><\/td>\n<\/tr>\n
\u676d\u5dde<\/span><\/strong><\/span><\/td>\n9\u670827-29\u65e5<\/span><\/td>\n\n

\u676d\u5dde-\u7b2c\u4e09\u5c4a\u5168\u56fd\u5e9f\u6c34.<\/span>\u5e9f\u6c14.<\/span>\u5371\u9669\u5904\u7406\u6280\u672f\u4ea4\u6d41\u4f1a<\/a><\/span><\/p>\n<\/td>\n<\/tr>\n

\u676d\u5dde<\/span><\/strong><\/td>\n10\u670811<\/span>-13<\/span>\u65e5<\/span><\/span><\/strong><\/td>\n\n

\u676d\u5dde<\/span>-2018\u201ccGMP\u6587\u4ef6\u7f16\u5236\u89c4\u8303<\/span>\u201d<\/span>\u4e13\u9898\u7814\u4fee\u73ed\u7684\u901a\u77e5<\/span><\/span><\/span><\/a><\/p>\n<\/td>\n<\/tr>\n

\u4e0a\u6d77<\/span><\/strong><\/td>\n<\/span>10\u670812<\/span>-14<\/span>\u65e5<\/span><\/span><\/strong><\/span><\/td>\n\n

\u4e0a\u6d77<\/span>–\u7b2c\u4e8c\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7528\u836f<\/span>GMP<\/span>\u5236\u5ea6\u8981\u70b9\u89e3\u6790\u53ca\u5e94\u7528\u5b9e\u65bd\u4e13\u9898\u57f9\u8bad\u73ed<\/span><\/span><\/span><\/a><\/p>\n<\/td>\n<\/tr>\n

\u6b66\u6c49<\/span><\/strong><\/td>\n10\u670819<\/span>-21<\/span>\u65e5<\/span><\/span><\/strong><\/td>\n\n

\u6b66\u6c49<\/span>\u201c\u836f\u4f01\u7ea0\u6b63\u4e0e\u9884\u9632\u63aa\u65bd\u5b9e\u65bd\u4e0e\u6539\u8fdb\u4e13\u9898\u57f9\u8bad\u73ed<\/span>\u201d<\/span><\/span><\/span><\/a><\/p>\n<\/td>\n<\/tr>\n

\u4e0a\u6d77<\/span><\/strong><\/span><\/td>\n10\u670819-21\u65e5<\/span><\/td>\n\n

\u4e0a\u6d77\u4e3e\u529e<\/span>\u201c\u5316\u5b66\u539f\u6599\u836f\u5236\u5907\u5de5\u827a\u5f00\u53d1\u5173\u952e\u63a7\u5236\u4e0e\u8d28\u91cf\u7814\u7a76\u5b9e\u8df5\u201d\u7814\u4fee\u73ed<\/a><\/span><\/span><\/p>\n<\/td>\n<\/tr>\n

\u676d\u5dde<\/span><\/td>\n10\u6708<\/span>25-27<\/span>\u65e5<\/span><\/span><\/strong><\/td>\n\n

\u676d\u5dde<\/span>–\u7b2c\u4e8c\u671f<\/span>2018<\/span>\u836f\u4f01<\/span>oos\/oot<\/span>\u8c03\u67e5\u8bef\u533a\u4e0e\u6539\u8fdb\u5b9e\u64cd\u4e13\u9898\u57f9\u8bad\u73ed<\/span><\/span><\/span><\/a><\/p>\n<\/td>\n<\/tr>\n

<\/span>\u5317\u4eac<\/span><\/td>\n10\u6708<\/span>24-26<\/span>\u65e5<\/span><\/span><\/strong><\/td>\n\n

\u5317\u4eac\u4e3e\u529e\u6ee1\u8db3\u6b27\u7f8e\u6807\u51c6\u7684\u4eff\u5236\u836f\u7814\u53d1\u4f53\u7cfb\u642d\u5efa\u7814\u8ba8\u73ed<\/span><\/span><\/span><\/a><\/p>\n<\/td>\n<\/tr>\n

\u5357\u4eac<\/strong><\/td>\n10\u6708<\/span>25-27<\/span>\u65e5<\/span><\/span><\/strong><\/td>\n\n

\u5357\u4eac<\/span>–\u4e3e\u529e<\/span>\u2018<\/span>\u836f\u7269\u7814\u53d1\u8d28\u91cf\u7ba1\u7406\u8fd0\u884c\u4e2d\u7684\u96be\u70b9\u5b9e\u65bd\u53ca\u4e34\u5e8a\u8bd5\u9a8c\u7528\u836f\u7269<\/span>GMP<\/span>\u5b9e\u65bd\u5173\u952e\u70b9\u63a7\u5236<\/span>\u2019<\/span>\u9ad8\u7ea7\u7814\u4fee\u73ed<\/span><\/span><\/span><\/a><\/p>\n<\/td>\n<\/tr>\n

\u676d\u5dde<\/strong><\/span><\/span><\/td>\n10\u6708<\/span>25-27<\/span>\u65e5<\/span><\/span><\/strong><\/td>\n\n

\u676d\u5dde<\/span>2018\u5e74\u529f\u80fd\u98df\u54c1<\/span>.<\/span>\u539f\u6599\u521b\u65b0\u4e0e\u6d3b\u6027\u6210\u5206\u5e94\u7528\u6280\u672f\u4e3b\u9898\u5cf0\u4f1a<\/span><\/span><\/span><\/a><\/p>\n

<\/span><\/strong><\/span><\/td>\n<\/tr>\n

<\/span>\u4e0a\u6d77<\/span><\/td>\n10\u6708<\/span>26-28<\/span>\u65e5<\/span><\/span><\/strong><\/td>\n\n

\u4e0a\u6d77\u4e3e\u529e<\/span>2018\u836f\u4f01\u8d28\u91cf\u8c03\u67e5\u6280\u672f\u6307\u5bfc\u4e13\u9898\u57f9\u8bad\u73ed<\/span><\/span><\/span><\/a><\/p>\n<\/td>\n<\/tr>\n

\u6d4e\u5357<\/span><\/td>\n10\u6708<\/span>26-28<\/span>\u65e5<\/span><\/span><\/strong><\/td>\n\n

\u6d4e\u5357<\/span>–\u7b2c\u4e8c\u671f\u5b9e\u9a8c\u5ba4\u7814\u53d1<\/span>qc<\/span>\u89c4\u8303\u7ba1\u7406\u4e0e<\/span>lch<\/span>\u6307\u5357\u53ca\u836f\u5178\u6700\u65b0\u8fdb\u5c55\u7814\u4fee\u73ed<\/span><\/span><\/span><\/a><\/p>\n<\/td>\n<\/tr>\n

\u5357\u4eac<\/strong><\/td>\n10\u6708<\/span>27-29<\/span>\u65e5<\/span><\/span><\/strong><\/td>\n\n

\u5357\u4eac<\/span>–\u5236\u836f\u4f01\u4e1a\u5982\u4f55\u5b9e\u73b0<\/span>gmp<\/span>\u6709\u6548\u8fd0\u8425\u6c9f\u901a\u9ad8\u7ea7\u7814\u8ba8\u4f1a<\/span><\/span><\/span><\/a><\/p>\n<\/td>\n<\/tr>\n

\u4e0a\u6d77<\/span><\/strong><\/td>\n10\u670812-14<\/span>\u65e5<\/span><\/strong><\/td>\n\n

\u4e0a\u6d77<\/span>–\u7b2c\u4e8c\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7528\u836f<\/span>GMP\u5236\u5ea6\u8981\u70b9\u89e3\u6790\u53ca\u5e94\u7528\u5b9e\u65bd\u4e13\u9898\u57f9\u8bad\u73ed<\/span><\/span><\/span><\/a><\/p>\n<\/td>\n<\/tr>\n

\u6b66\u6c49<\/span><\/strong><\/td>\n\n

10\u670819-21<\/span>\u65e5<\/span><\/strong><\/span><\/p>\n


<\/p>\n<\/td>\n

\n

\u6b66\u6c49<\/span>\u201c\u836f\u4f01\u7ea0\u6b63\u4e0e\u9884\u9632\u63aa\u65bd\u5b9e\u65bd\u4e0e\u6539\u8fdb\u4e13\u9898\u57f9\u8bad\u73ed<\/span>\u201d<\/span><\/a><\/p>\n<\/td>\n<\/tr>\n

\u91cd\u5e86<\/span><\/strong><\/td>\n11\u67081<\/span>-3<\/span>\u65e5<\/span><\/span><\/strong><\/td>\n\n

\u91cd\u5e86<\/span>–\u836f\u54c1\u5236\u5907\u5de5\u827a\u5f00\u53d1\u4e0e\u5de5\u827a\u9a8c\u8bc1<\/span>\/<\/span>\u6301\u7eed\u5de5\u827a\u786e\u5b9a\u7814\u7a76\u4e0e\u5b9e\u65bd\u7814\u4fee\u73ed<\/span><\/a><\/span><\/span><\/p>\n<\/td>\n<\/tr>\n

\u676d\u5dde<\/span><\/strong><\/td>\n11\u67081<\/span>-3<\/span>\u65e5<\/span><\/span><\/strong><\/td>\n\n

\u676d\u5dde<\/span>–<\/span><\/span>\u4e3e\u529e<\/span>2018<\/span>\u533b\u836f\u5316\u5de5\u5b89\u5168\u751f\u4ea7\u4e0e\u5de5\u827a\u5b89\u5168\u7ba1\u7406\u7814\u8ba8\u73ed<\/span><\/a><\/span><\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


<\/p>\n


<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

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