{"id":51952,"date":"2018-09-21T01:00:00","date_gmt":"2018-09-26T02:23:24","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/26\/%e6%81%92%e7%91%9e%e5%8e%89%e5%ae%b3%e4%ba%86%ef%bc%81%e5%85%a5%e5%9b%b4%e5%85%a8%e7%90%83%e5%b8%82%e5%80%bc%e6%9c%80%e9%ab%98%e8%8d%af%e4%bc%81%e6%a6%9c\/"},"modified":"2018-09-26T10:23:26","modified_gmt":"2018-09-26T02:23:26","slug":"%e6%81%92%e7%91%9e%e5%8e%89%e5%ae%b3%e4%ba%86%ef%bc%81%e5%85%a5%e5%9b%b4%e5%85%a8%e7%90%83%e5%b8%82%e5%80%bc%e6%9c%80%e9%ab%98%e8%8d%af%e4%bc%81%e6%a6%9c","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/51952\/","title":{"rendered":"\u6052\u745e\u5389\u5bb3\u4e86\uff01\u5165\u56f4\u5168\u7403\u5e02\u503c\u6700\u9ad8\u836f\u4f01\u699c"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"margin: 10px 8px;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;white-space: normal;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 180, 203);text-align: justify;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5168\u7403\u5e02\u503c\u6700\u9ad8\u836f\u4f01\u699c\uff0c\u6052\u745e\u4e0a\u699c<\/span><\/strong><\/p>\n<p style=\"margin-top: 10px;margin-right: 16px;margin-left: 16px;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"     style=\"margin-top: 8px;margin-right: auto;margin-left: auto;color: rgb(0, 180, 204);font-size: 8px;letter-spacing: 2.2px;display: block;box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: 46px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/3-1537928605.png\" alt=\"\u6052\u745e\u5389\u5bb3\u4e86\uff01\u5165\u56f4\u5168\u7403\u5e02\u503c\u6700\u9ad8\u836f\u4f01\u699c\" title=\"\u6052\u745e\u5389\u5bb3\u4e86\uff01\u5165\u56f4\u5168\u7403\u5e02\u503c\u6700\u9ad8\u836f\u4f01\u699c\"><\/p>\n<p style=\"text-align: justify;margin-left: 8px;margin-right: 8px;letter-spacing: 1.5px;line-height: 1.5em;\"><br  \/><\/p>\n<p style=\"text-align: justify;margin-left: 8px;margin-right: 8px;letter-spacing: 1.5px;line-height: 1.5em;\"><span style=\"font-size: 15px;color: rgb(83, 83, 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8px;margin-right: 8px;letter-spacing: 1.5px;line-height: 1.5em;\"><span style=\"font-size: 15px;color: rgb(83, 83, 83);\">\u4ece\u6570\u636e\u6765\u770b\uff0c\u9ed8\u6c99\u4e1c\u3001\u62dc\u8033\u3001\u845b\u5170\u7d20\u53f2\u514b\u3001\u793c\u6765\u3001CSL\u3001\u590f\u5c14\u7684\u5e02\u503c\u90fd\u5b9e\u73b0\u4e86\u540c\u671f\u4e24\u4f4d\u6570\u7684\u589e\u957f\uff0c\u767e\u65f6\u7f8e\u65bd\u8d35\u5b9d\u548c\u65b0\u57fa\u5219\u4e0b\u964d\u4e86 10% \u4ee5\u4e0a\uff0c\u524d\u8005\u7684\u673a\u6784\u6295\u8d44\u8005\u5728\u8fd9\u671f\u95f4\u4ea4\u6613\u4e86\u5927\u91cf\u80a1\u7968\uff0c\u88ab\u8ba4\u4e3a\u5f71\u54cd\u4e86\u5e02\u503c\u8868\u73b0\uff0c\u540e\u8005\u5219\u662f\u53d7\u5230\u4e00\u4e9b\u5173\u952e\u7ba1\u7ebf\u836f\u7269\u632b\u8d25\u7684\u5f71\u54cd\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;margin-left: 8px;margin-right: 8px;letter-spacing: 1.5px;line-height: 1.5em;\"><span style=\"font-size: 15px;color: rgb(83, 83, 83);\">\u4ece Q2 \u7684\u5e02\u573a\u884c\u52a8\u6765\u770b\uff0c\u53cd\u6620\u51fa\u5927\u578b\u5236\u836f\u516c\u53f8\u4e13\u6ce8\u4e8e\u6838\u5fc3\u4e1a\u52a1\u9886\u57df\u589e\u957f\u8d8b\u52bf\uff0c\u6bd4\u5982\u65bd\u8d35\u5b9d\u6253\u7b97\u51fa\u552e\u5176\u6cd5\u56fd\u6d88\u8d39\u8005\u5065\u5eb7\u4e1a\u52a1\uff0c\u5b9d\u6d01\u6536\u8d2d\u4e86\u9ed8\u514b\u7684\u7ef4\u751f\u7d20\u54c1\u724c\uff0cGSK \u4ee5 130 \u4ebf\u7f8e\u5143\u6536\u8d2d\u548c\u8bfa\u534e\u5408\u8d44\u7684\u6d88\u8d39\u8005\u5065\u5eb7\u516c\u53f8\uff0c\u8f89\u745e\u8ba1\u5212\u5265\u79bb\u5176\u6b27\u6d32\u4eff\u5236\u836f\u4e1a\u52a1\u7b49\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;margin-left: 8px;margin-right: 8px;letter-spacing: 1.5px;line-height: 1.5em;\"><span style=\"font-size: 15px;color: rgb(83, 83, 83);\">\u672a\u6765\u51e0\u5e74\uff0c\u8fd9\u4efd\u699c\u5355\u4f1a\u6709\u4ec0\u4e48\u53d8\u5316\u5462\uff1f\u4f1a\u4e0d\u4f1a\u6709\u66f4\u591a\u4e2d\u56fd\u836f\u4f01\u8fdb\u5165\uff1f<\/span><span style=\"font-size: 12px;color: rgb(178, 178, 178);\">\uff08via. \u533b\u836f\u4ee3\u8868\uff09<\/span><\/p>\n<p style=\"white-space: normal;text-align: justify;margin-left: 8px;margin-right: 8px;letter-spacing: 1.5px;line-height: 1.5em;\"><br  \/><\/p>\n<p style=\"margin: 10px 8px;white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 180, 203);text-align: justify;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u4fe1\u8fbe\u751f\u7269\u516c\u5e03\u4fe1\u8fea\u5229\u5355\u6297\u6700\u65b0\u7814\u7a76\u7ed3\u679c<\/span><\/strong><\/p>\n<p style=\"margin-top: 10px;margin-right: 16px;margin-left: 16px;white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"     style=\"margin-top: 8px;margin-right: auto;margin-left: auto;color: rgb(0, 180, 204);font-size: 8px;letter-spacing: 2.2px;display: block;box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: 46px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/3-1537928606.png\" alt=\"\u6052\u745e\u5389\u5bb3\u4e86\uff01\u5165\u56f4\u5168\u7403\u5e02\u503c\u6700\u9ad8\u836f\u4f01\u699c\" title=\"\u6052\u745e\u5389\u5bb3\u4e86\uff01\u5165\u56f4\u5168\u7403\u5e02\u503c\u6700\u9ad8\u836f\u4f01\u699c\"><\/p>\n<p style=\"white-space: normal;text-align: justify;margin-left: 8px;margin-right: 8px;letter-spacing: 1.5px;line-height: 1.5em;\"><span style=\"font-size: 15px;color: rgb(83, 83, 83);\"><br  \/><\/span><\/p>\n<p style=\"white-space: normal;text-align: justify;margin-left: 8px;margin-right: 8px;letter-spacing: 1.5px;line-height: 1.5em;\"><span style=\"font-size: 15px;color: rgb(83, 83, 83);\">\u5728\u7b2c\u4e8c\u5341\u4e00\u5c4a\u5168\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u5927\u4f1a\u66a8 2018 \u5e74 CSCO \u5b66\u672f\u5e74\u4f1a\u4e0a\u516c\u5e03\u4fe1\u8fea\u5229\u5355\u6297\uff08\u5168\u4eba\u6e90\u6297 PD-1 \u5355\u514b\u9686\u6297\u4f53\uff0c\u7814\u53d1\u4ee3\u53f7 IBI308\uff09\u5355\u836f\u6cbb\u7597\u65e2\u5f80\u6807\u51c6\u6cbb\u7597\u5931\u8d25\u7684\u795e\u7ecf\u5185\u5206\u6ccc\u80bf\u7624\u7684\u4e00\u9879 Ib \u671f\u7814\u7a76\u7ed3\u679c\uff08NCT02937116\uff09\u3002<\/span><\/p>\n<p style=\"white-space: normal;\"><br  \/><\/p>\n<p style=\"white-space: normal;text-align: justify;margin-left: 8px;margin-right: 8px;letter-spacing: 1.5px;line-height: 1.5em;\"><span style=\"font-size: 15px;color: rgb(83, 83, 83);\">\u5728\u76ee\u524d\u56fd\u9645\u4e0a\u5df2\u516c\u5e03\u7684 PD-1 \u5355\u6297\u7528\u4e8e\u795e\u7ecf\u5185\u5206\u6ccc\u80bf\u7624\u6cbb\u7597\u7684\u4e34\u5e8a\u7814\u7a76\u4e2d\uff0c\u8fd9\u9879\u7814\u7a76\u7684\u5165\u7ec4\u4eba\u6570\u4f4d\u5c45\u524d\u5217\u3002\u8be5\u7814\u7a76\u5171\u6709 25 \u4f8b\u60a3\u8005\u5165\u7ec4\uff0c\u5176\u4e2d 22 \u4f8b\u4e3a\u53ef\u8bc4\u4f30\u60a3\u8005\uff0c\u5ba2\u89c2\u7f13\u89e3\u7387\uff08ORR\uff09\u8fbe\u5230 22.7%\uff1b19 \u4f8b\u4e3a\u5206\u5316\u5dee\u7684\u795e\u7ecf\u5185\u5206\u6ccc\u764c\uff0cORR \u4e3a 26.3%\uff0c\u663e\u793a\u51fa\u4e86\u4ee4\u4eba\u9f13\u821e\u7684\u6297\u80bf\u7624\u6d3b\u6027\u3002\u622a\u81f3 2018 \u5e74 6 \u6708 28 \u65e5\uff0c\u4e2d\u4f4d\u7f13\u89e3\u6301\u7eed\u65f6\u95f4\u4e3a 5.8 \u4e2a\u6708\uff0c\u4e2d\u4f4d\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\u4e3a 2.2 \u4e2a\u6708\uff0c\u4e2d\u4f4d\u751f\u5b58\u65f6\u95f4\u5c1a\u672a\u8fbe\u5230\u3002\u4fe1\u8fea\u5229\u5355\u6297\u5728\u795e\u7ecf\u5185\u5206\u6ccc\u80bf\u7624\u4e2d\u7684\u5b89\u5168\u6027\u7279\u5f81\u4e0e\u5176\u4ed6\u7624\u79cd\u76f8\u4f3c\u3002<\/span><\/p>\n<p style=\"white-space: normal;text-align: justify;margin-left: 8px;margin-right: 8px;letter-spacing: 1.5px;line-height: 1.5em;\"><br  \/><\/p>\n<p style=\"margin: 10px 8px;white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 180, 203);text-align: justify;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u590d\u661f\u533b\u836f\u516c\u5e03HLX-01\u6700\u65b0\u7814\u6210\u679c<\/span><\/strong><\/p>\n<p style=\"margin-top: 10px;margin-right: 16px;margin-left: 16px;white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"     style=\"margin-top: 8px;margin-right: auto;margin-left: auto;color: rgb(0, 180, 204);font-size: 8px;letter-spacing: 2.2px;display: block;box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: 46px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/9-1537928606.png\" alt=\"\u6052\u745e\u5389\u5bb3\u4e86\uff01\u5165\u56f4\u5168\u7403\u5e02\u503c\u6700\u9ad8\u836f\u4f01\u699c\" title=\"\u6052\u745e\u5389\u5bb3\u4e86\uff01\u5165\u56f4\u5168\u7403\u5e02\u503c\u6700\u9ad8\u836f\u4f01\u699c\"><\/p>\n<p style=\"margin-top: 10px;margin-right: 16px;margin-left: 16px;white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"color: rgb(83, 83, 83);font-size: 15px;letter-spacing: 1.5px;font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\">9 \u6708 20 \u65e5\uff0c\u5728 CSCO \u5e74\u4f1a\u4e0a\uff0c\u4e0a\u6d77\u590d\u661f\u533b\u836f\u63a7\u80a1\u5b50\u516c\u53f8\u590d\u5b8f\u6c49\u9716\u81ea\u4e3b\u7814\u53d1\u7684\u5229\u59a5\u6614\u5355\u6297\u751f\u7269\u7c7b\u4f3c\u836f\uff08HLX-01\uff09\u516c\u5e03\u5173\u952e 3 \u671f\u4e34\u5e8a\u6570\u636e\uff0c\u5229\u59a5\u6614\u5355\u6297\u751f\u7269\u7c7b\u4f3c\u836f\u4e0e\u539f\u7814\u836f\uff08\u7f8e\u7f57\u534e\u00ae\uff09\u5728\u6cbb\u7597 CD20 \u9633\u6027\u5f25\u6f2b\u578b\u5927 B 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!important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"margin-right: 8px;margin-left: 8px;max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"       style=\"box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: 677px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/6-1537928606.png\" 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