{"id":53592,"date":"2018-09-27T01:00:00","date_gmt":"2018-09-30T01:46:37","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/30\/%e8%af%ba%e5%8d%8e%e5%ae%a3%e5%b8%83%ef%bc%8c%e8%a3%81%e5%91%982200%e4%ba%ba\/"},"modified":"2018-09-30T09:46:38","modified_gmt":"2018-09-30T01:46:38","slug":"%e8%af%ba%e5%8d%8e%e5%ae%a3%e5%b8%83%ef%bc%8c%e8%a3%81%e5%91%982200%e4%ba%ba","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/53592\/","title":{"rendered":"\u8bfa\u534e\u5ba3\u5e03\uff0c\u88c1\u54582200\u4eba"},"content":{"rendered":"
\n

\u8bfa\u534e\u5ba3\u5e03\uff0c\u5c06\u5728\u5176\u603b\u90e8\u745e\u58eb\u88c1\u54582200\u540d\uff0c\u4e3b\u8981\u6d89\u53ca\u836f\u54c1\u751f\u4ea7\u90e8\u95e8\u548c\u5e02\u573a\u90e8\u95e8\uff0c\u4ee5\u914d\u5408\u6b64\u524d\u66fe\u5bf9\u5916\u516c\u5e03\u7684\u7ec6\u80de\u4e0e\u57fa\u56e0\u7597\u6cd5\u751f\u4ea7\u57fa\u5730\u7b79\u5efa\u5de5\u7a0b\u3002<\/span><\/em><\/p>\n

 <\/span><\/p>\n

 <\/span>\u258d<\/strong><\/span><\/span><\/strong>\u88c1\u54582200\u4eba\uff0c\u521b\u9020450\u4e2a\u65b0\u5c31\u4e1a\u673a\u4f1a<\/span><\/strong><\/span><\/p>\n

 <\/span><\/p>\n

\u6628\u65e5\uff089\u670825\u65e5\uff09\uff0c\u8bfa\u534e\u5ba3\u5e03\uff0c\u8ba1\u5212\u5728\u5176\u603b\u90e8\u745e\u58eb\u524a\u51cf2200\u591a\u4e2a\u5de5\u4f5c\u5c97\u4f4d\uff0c\u6b64\u4e3e\u5c06\u6ce2\u53ca1500\u4f4d\u836f\u54c1\u751f\u4ea7\u4e00\u7ebf\u5458\u5de5\u4ee5\u53ca\u7ea6700\u540d\u5546\u4e1a\u670d\u52a1\u90e8\u95e8\u804c\u5458\u3002\u76ee\u524d\uff0c\u8bfa\u534e\u5728\u745e\u58eb\u5404\u5730\u5171\u62e5\u6709\u96c7\u54581.3\u4e07\u540d\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u8bfa\u534e\u96c6\u56e2\u9996\u5e2d\u6267\u884c\u5b98\u74e6\u65af\u2022\u7eb3\u897f\u59c6\u6c57(Vas Narasimhan)\u5728\u63a5\u53d7\u91c7\u8bbf\u65f6\u8868\u793a\uff1a\u88c1\u5458\u662f2016\u5e74\u6218\u7565\u7684\u4e00\u90e8\u5206\uff0c\u8be5\u6218\u7565\u5c06\u57282020\u5e74\u4e3a\u516c\u53f8\u7684\u751f\u4ea7\u7f51\u7edc\u8282\u7701\u7ea610\u4ebf\u7f8e\u5143\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u8d44\u6599\u663e\u793a\uff0c\u8bfa\u534e\u5c06\u5728\u4f4d\u4e8e\u745e\u58eb\u5df4\u585e\u5c14(Basel)\u3001\u65bd\u6cf0\u56e0(Stein)\u3001\u6d1b\u8fe6\u8bfa(Locarno)\u548c\u745e\u58eb\u77e5\u540d\u5316\u5de5\u5de5\u4e1a\u533a\u65bd\u97e6\u6cfd\u54c8\u52d2(Schweizerhalle)\u7684\u751f\u4ea7\u57fa\u5730\u5171\u8ba1\u88c1\u51cf\u7ea61500\u4e2a\u5de5\u4f5c\u5c97\u4f4d\uff0c\u5728\u745e\u58eb\u5546\u4e1a\u670d\u52a1\u90e8\u95e8\u88c1\u51cf\u7ea6700\u4e2a\u804c\u4f4d\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u6bd4\u8f83\u660e\u663e\u7684\u662f\uff0c\u5bf9\u8bfa\u534e\u800c\u8a00\uff0c\u524a\u51cf\u662f\u4e3a\u4e86\u4e13\u6ce8\u91cd\u70b9\u6218\u7565\u3002\u636e\u8bfa\u534e\u900f\u9732\uff0c\u88c1\u5458\u524d\u5c31\u5df2\u521b\u9020\u4e86450\u4e2a\u65b0\u7684\u5c31\u4e1a\u673a\u4f1a\uff0c\u4ee5\u914d\u5408\u6b64\u524d\u66fe\u5bf9\u5916\u516c\u5e03\u7684\u7ec6\u80de\u4e0e\u57fa\u56e0\u7597\u6cd5\u751f\u4ea7\u57fa\u5730\u7b79\u5efa\u5de5\u7a0b\u3002\u6b64\u5916\uff0c\u8bfa\u534e\u627f\u8bfa\uff1a\u786e\u4fdd\u6bcf\u5e74\u65a5\u8d4430\u4ebf\u745e\u90ce\u4e13\u9879\u8d44\u91d1\u7528\u4e8e\u65b0\u836f\u54c1\u53ca\u65b0\u7597\u6cd5\u7684\u7814\u53d1\u4e0e\u751f\u4ea7\u3002<\/span><\/p>\n

 <\/span><\/p>\n

 <\/span>\u258d<\/strong><\/span><\/span><\/strong>\u8bfa\u534e\u4e13\u6ce8\u521b\u65b0\u836f\uff0c\u52a8\u4f5c\u9891\u9891<\/span><\/strong><\/span><\/p>\n

 <\/span><\/p>\n

\u4e8b\u5b9e\u4e0a\uff0c\u88c1\u5458\u53ea\u662f\u4e8b\u60c5\u53d1\u5c55\u7684\u8868\u8c61\uff0c\u4ece\u672c\u8d28\u4e0a\u770b\uff0c\u8bfa\u534e\u5bf9\u836f\u54c1\u751f\u4ea7\u4e00\u7ebf\u5458\u5de5\u4ee5\u53ca\u5546\u52a1\u670d\u52a1\u90e8\u95e8\u804c\u5458\u7684\u88c1\u64a4\uff0c\u4f53\u73b0\u4e86\u5176\u4e13\u6ce8\u6838\u5fc3\u4e1a\u52a1\u7684\u53d1\u5c55\u8f68\u8ff9\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u8d44\u6599\u663e\u793a\uff0c\u8bfa\u534e\u5c06\u6218\u7565\u96c6\u4e2d\u5728\u91cd\u70b9\u836f\u7269\u7684\u7814\u53d1\u4e0a\uff0c\u5305\u62ec\u82b1\u8d39\u6570\u5341\u4e07\u7f8e\u5143\u7684\u57fa\u56e0\u7597\u6cd5\u3002\u6b64\u6b21\u88c1\u5458\uff0c\u610f\u5728\u8282\u7ea6\u6210\u672c\uff0c\u6295\u5165\u7814\u53d1\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u8fd1\u5e74\u6765\uff0c\u8bfa\u534e\u5c31\u4e00\u76f4\u901a\u8fc7\u8d44\u672c\u91cd\u7ec4\u3001\u653e\u5f03\u975e\u6838\u5fc3\u4e1a\u52a1\u7b49\u65b9\u5f0f\uff0c\u6765\u5f3a\u5316\u81ea\u8eab\u7684\u4f18\u52bf\u4e1a\u52a1\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u5c24\u5176\u662f\u4eca\u5e74\uff0c\u8bfa\u534e\u7684\u52a8\u4f5c\u9891\u9891\uff0c\u4e0d\u65ad\u5206\u62c6\u516c\u53f8\u975e\u6838\u5fc3\u4e1a\u52a1\u3002<\/span><\/p>\n

 <\/span><\/p>\n

9<\/span>\u6708\u521d\uff0c\uff0c\u8bfa\u534e\u516c\u53f8\u65e5\u524d\u5ba3\u5e03\uff0c\u5df2\u7ecf\u540c\u610f\u5c06\u5176\u5b50\u516c\u53f8\u5c71\u5fb7\u58eb\uff08Sandoz\uff09\u5728\u7f8e\u56fd\u7684\u90e8\u5206\u4e1a\u52a1\uff0c\u7279\u522b\u662fSandoz\u7f8e\u56fd\u76ae\u80a4\u75c5\u4e1a\u52a1\u548c\u7f8e\u56fd\u53e3\u670d\u4eff\u5236\u56fa\u4f53\u5236\u5242\u677f\u5757\uff0c\u4ee510\u4ebf\u7f8e\u5143\u7684\u4ef7\u683c\u51fa\u552e\u7ed9\u963f\u62c9\u5bbe\u5ea6\uff08\u7f8e\u56fd\uff09\u5236\u836f\u516c\u53f8\u3002<\/span><\/p>\n

 <\/span><\/p>\n

7\u670812\u65e5\uff0c<\/span>\u8bfa\u534e\u516c\u53f8\u5ba3\u5e03\u5c06\u7ec8\u6b62\u6297\u751f\u7d20\u3001\u6297\u75c5\u6bd2\u836f\u7269\u7684\u65e9\u671f\u7814\u53d1<\/span>\uff0c\u5e76\u88c1\u5458140\u4eba\u3002\u8bfa\u534e\u8868\u793a\uff0c\u867d\u7136\u8fd9\u4e9b\u9879\u76ee\u7684\u79d1\u5b66\u57fa\u7840\u5f88\u575a\u5b9e\uff0c\u4f46\u56e0\u8d44\u6e90\u6709\u9650\uff0c\u8bfa\u534e\u51b3\u5b9a\u805a\u7126\u5728\u80fd\u66f4\u597d\u5730\u6539\u5584\u75c5\u4eba\u5065\u5eb7\u7684\u9886\u57df\u3002<\/span><\/p>\n

 <\/span><\/p>\n

6\u6708\u5e95\uff0c\u8bfa\u534e\u516c\u53f8\u5ba3\u5e03\u653e\u5f03\u5176\u7231\u5c14\u5eb7\u773c\u79d1\u62a4\u7406\u90e8\u95e8\uff0c\u540c\u65f6\u542f\u52a8\u56de\u8d2d\u4e0d\u8d85\u8fc750\u4ebf\u7f8e\u5143\u7684\u80a1\u7968\u3002<\/span>\u82e5\u5265\u79bb\u6210\u529f\uff0c\u7231\u5c14\u5eb7\u672a\u6765\u5c06\u6210\u4e3a\u4e00\u5bb6\u72ec\u7acb\u7684\u516c\u53f8\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u6b64\u524d\uff0c\u8bfa\u534e\u4e5f\u4e0eGSK\u4e92\u6362\u4e86\u80bf\u7624\u548c\u75ab\u82d7\u4e1a\u52a1\uff0c\u4ee52.75\u4ebf\u5265\u79bb\u65d7\u4e0b\u6d41\u611f\u75ab\u82d7\u4e1a\u52a1\uff0c\u5c06\u52a8\u7269\u4fdd\u5065\u54c1\u4e1a\u52a1\u4ee554\u4ebf\u7f8e\u91d1\u7684\u4ef7\u683c\u51fa\u552e\u7ed9\u793c\u6765\u2026\u2026<\/span><\/p>\n

 <\/span><\/p>\n

\u4e0e\u6b64\u540c\u65f6\uff0c2018\u5e746\u6708\uff0c\u8bfa\u534e\u3001\u5409\u5217\u5fb7\u65d7\u4e0b\u7684CAR-T\u836f\u7269Kymriah\u548cYescarta\u6536\u5230\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\u4eba\u7528\u836f\u54c1\u59d4\u5458\u4f1a(CHMP)\u7684\u63a8\u8350\uff1b4\u6708\uff0c\u8bfa\u534e\u4e0eAveXis\u516c\u53f8\u8fbe\u6210\u534f\u8bae\uff0c\u4ee587\u4ebf\u7f8e\u5143\u6536\u8d2d\u8fd9\u5bb6\u5728\u7f8e\u56fd\u7eb3\u65af\u8fbe\u514b\u4e0a\u5e02\u7684\u5904\u4e8e\u4e34\u5e8a\u9636\u6bb5\u7684\u57fa\u56e0\u6cbb\u7597\u516c\u53f8\u2026\u2026<\/span><\/p>\n

 <\/span><\/p>\n

\u8bfa\u534e\u66fe\u8868\u793a\uff0c\u8981\u6210\u4e3a\u66f4\u4e13\u6ce8\u7684\u533b\u836f\u516c\u53f8\uff0c\u5de9\u56fa\u5904\u65b9\u836f\u7684\u9886\u5148\u5730\u4f4d\u3002<\/span><\/p>\n

 <\/span><\/p>\n

 <\/span>\u258d<\/strong><\/span><\/span><\/strong>\u9664\u4e86\u8bfa\u534e\uff0c\u66f4\u591a\u5916\u4f01\u4e5f\u5728\u8fd9\u6837\u505a<\/span><\/strong><\/span><\/p>\n

 <\/span><\/p>\n

\u4e3a\u4e86\u805a\u7126\u6838\u5fc3\u9886\u57df\uff0c\u66f4\u591a\u5916\u4f01\u901a\u8fc7\u5265\u79bb\u6838\u5fc3\u4e1a\u52a1\uff0c\u5265\u79bb\u4ea7\u54c1\uff0c\u8f6c\u8ba9\u9500\u552e\u6743\uff0c\u751a\u81f3\u88c1\u5458\u7b49\u65b9\u5f0f\u6765\u8282\u7ea6\u8d44\u672c\uff0c\u96c6\u4e2d\u53d1\u529b\u521b\u65b0\u836f\u9886\u57df\u3002<\/span><\/p>\n

 <\/span> <\/span><\/p>\n

\u4f8b\u5982\uff0c\u6cf0\u51cc\u533b\u836f\u5ba3\u5e03\u6536\u8d2d\u8bfa\u534e\u5236\u836f\u9aa8\u79d1\u54c1\u724c\u201c\u5bc6\u76d6\u606f\u201d\uff0c\u5305\u62ec\u76f8\u5173\u77e5\u8bc6\u4ea7\u6743\u3001\u8bb8\u53ef\u8bc1\u53ca\u5176\u4ed6\u8d44\u4ea7\uff0c\u4ea4\u6613\u91d1\u989d\u4e3a1.45\u4ebf\u7f8e\u5143\uff1b\u6cd5\u56fdLFB\u516c\u53f8\u548c\u4e9a\u5b9d\u836f\u4e1a\u5171\u540c\u5c06\u5168\u7403\u9886\u5148\u7684\u4eba\u8840\u767d\u86cb\u767d\u4ea7\u54c1VIALEBEX\u5f15\u5165\u4e2d\u56fd\uff0c\u4e9a\u5b9d\u836f\u4e1a\u6210\u4e3a\u8be5\u4ea7\u54c1\u5728\u4e2d\u56fd\u5e02\u573a\u7684\u72ec\u5bb6\u4ee3\u7406\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u8de8\u56fd\u836f\u4f01\u88c1\u5458\u7684\u76f8\u5173\u4fe1\u606f\u4e5f\u53d8\u5f97\u8d8a\u6765\u8d8a\u591a\uff0c\u4f3c\u4e4e\u5916\u4f01\u88c1\u5458\u7684\u98ce\u6f6e\u5df2\u7ecf\u5230\u6765\u3002<\/span><\/p>\n

 <\/span><\/p>\n

9<\/span>\u670819\u65e5\uff0c\u845b\u5170\u7d20\u53f2\u514b\u5ba3\u5e03\uff0c\u5c06\u5728\u7f8e\u56fd\u88c1\u51cf650\u4e2a\u804c\u4f4d\uff0c\u5305\u62ec200\u4e2a\u5185\u52e4\u4eba\u5458\uff0c\u4ee5\u53ca450\u4e2a\u533b\u836f\u4ee3\u8868\u804c\u4f4d\u3002<\/span><\/p>\n

 <\/span><\/p>\n

9<\/span>\u670818\u65e5\uff0c\u8bfa\u548c\u8bfa\u5fb7\u5b98\u65b9\u7f51\u7ad9\u53d1\u5e03\u300a\u8f6c\u53d8\u7814\u53d1\u65b9\u5f0f\u7684\u8ba1\u5212\u300b\uff0c\u5ba3\u5e03\u5728\u4e2d\u56fd\u548c\u4e39\u9ea6\u88c1\u5458400\u4eba\uff0c\u4f5c\u4e3a\u5176\u7814\u53d1\u90e8\u95e8\u91cd\u7ec4\u7684\u4e00\u90e8\u5206\u3002<\/span><\/p>\n

 <\/span><\/p>\n

9<\/span>\u670811\u65e5\uff0c\u6b66\u7530\u516c\u53f8\u516c\u5e03\u4e86\u5173\u95ed\u829d\u52a0\u54e5\u5730\u533a\u7f8e\u56fd\u603b\u90e8\u7684\u8ba1\u5212\uff0c\u5e76\u5c06\u5176\u7f8e\u56fd\u4e1a\u52a1\u96c6\u4e2d\u5728Shire\u8fd0\u8425\u7684\u6ce2\u58eb\u987f\u5730\u533a\uff0c\u6b64\u4e3e\u5c06\u5173\u95ed1000\u4e2a\u76f8\u5173\u5c97\u4f4d\uff0c\u5e76\u627f\u8bfa\u5c06\u524a\u51cf\u7ea67\uff05\u7684\u5408\u5e76\u5458\u5de5\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u534e\u5c14\u8857\u65e5\u62a57\u6708\u4efd\u62a5\u9053\uff0c\u53e6\u4e00\u5bb6\u745e\u58eb\u5236\u836f\u5de8\u5934\u7f57\u6c0f\u63a7\u80a1\u516c\u53f8\u4e5f\u8ba1\u5212\u901a\u8fc7\u5173\u95ed\u5176\u5730\u533a\u529e\u4e8b\u5904\u6765\u91cd\u7ec4\u5176\u7ed3\u6784\u3002<\/span><\/p>\n

 <\/span><\/p>\n

2017<\/span>\u5e7411\u6708\uff0c\u5168\u7403\u5236\u836f\u5de8\u5934\u793c\u6765\uff08Lilly\uff09\u516c\u5e03\u4e86\u5927\u5e45\u88c1\u5458\u8ba1\u5212\uff0c\u76ee\u6807\u662f\u6bcf\u5e74\u8282\u77015\u4ebf\u7f8e\u5143\uff0c\u7ea62300\u540d\u5458\u5de5\u81ea\u613f\u63d0\u524d\u9000\u4f11\u3002<\/span><\/p>\n

 <\/span><\/p>\n

2017<\/span>\u5e7410\u6708\uff0c\u9ed8\u6c99\u4e1c\u5ba3\u5e03\u91cd\u7ec4\u9500\u552e\u961f\u4f0d,\u88c1\u54581800\u4eba\u3002<\/span><\/p>\n

 <\/span><\/p>\n

2017<\/span>\u5e748\u6708\uff0c\u68af\u74e6\u5ba3\u5e03\u88c1\u54587000\u4eba\uff0c\u5e76\u57282017\u5e74\u7ed3\u675f\u524d\u9000\u51fa\u591a\u4e2a\u5e02\u573a\uff0c\u5728\u672a\u67652\u5e74\u5185\u5173\u95ed15\u4e2a\u5de5\u5382\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u4e00\u76f4\u4ee5\u6765\uff0c\u8de8\u56fd\u836f\u4f01\u90fd\u5728\u901a\u8fc7\u5265\u79bb\u975e\u6838\u5fc3\u4e1a\u52a1\u6765\u8f6c\u578b\uff0c\u4eca\u5e74\u5c24\u5176\u8868\u73b0\u5728\u8de8\u56fd\u4f01\u4e1a\u7684\u88c1\u5458\u4e0a\uff0c\u4e5f\u8bb8\u5728\u672a\u6765\uff0c\u6211\u4eec\u8fd8\u4f1a\u770b\u5230\u8de8\u56fd\u836f\u4f01\u7684\u66f4\u591a\u52a8\u4f5c\u3002<\/span><\/p>\n

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