{"id":54958,"date":"2018-09-29T01:00:00","date_gmt":"2018-09-30T02:00:08","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/30\/%e9%80%9f%e9%80%92-7-85%e4%ba%bf%e7%be%8e%e5%85%83%ef%bc%8c%e7%bd%97%e6%b0%8f%e9%87%8d%e8%b5%84%e6%8b%93%e5%b1%95%e8%82%bf%e7%98%a4%e5%85%8d%e7%96%ab%e7%96%97%e6%b3%95\/"},"modified":"2018-09-30T10:00:10","modified_gmt":"2018-09-30T02:00:10","slug":"%e9%80%9f%e9%80%92-7-85%e4%ba%bf%e7%be%8e%e5%85%83%ef%bc%8c%e7%bd%97%e6%b0%8f%e9%87%8d%e8%b5%84%e6%8b%93%e5%b1%95%e8%82%bf%e7%98%a4%e5%85%8d%e7%96%ab%e7%96%97%e6%b3%95","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/54958\/","title":{"rendered":"\u901f\u9012 | 7.85\u4ebf\u7f8e\u5143\uff0c\u7f57\u6c0f\u91cd\u8d44\u62d3\u5c55\u80bf\u7624\u514d\u75ab\u7597\u6cd5"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><strong style=\"white-space: normal;font-size: 15px;max-width: 100%;color: rgb(51, 51, 51);\"><strong style=\"max-width: 100%;line-height: 32px;font-size: 20px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: SimSun;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 32px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 1.75em;font-family: \u5fae\u8f6f\u96c5\u9ed1, sans-serif;font-size: 15px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);font-family: \u6977\u4f53;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u258e\u836f\u660e<\/span><\/strong><strong style=\"max-width: 100%;line-height: 1.75em;font-family: \u5fae\u8f6f\u96c5\u9ed1, sans-serif;font-size: 15px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 112, 192);font-family: \u6977\u4f53;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5eb7\u5fb7\/\u62a5\u9053<\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><strong><span style=\"font-size: 15px;\">\u7f57\u6c0f\uff08Roche\uff09<\/span><\/strong><span style=\"font-size: 15px;\">\u96c6\u56e2\u4eca\u65e5\u5ba3\u5e03\uff0c<strong>\u5c06\u4ee57.85\u4ebf\u7f8e\u5143\u6536\u8d2d\u4e13\u6ce8\u4e8e\u7814\u53d1\u9488\u5bf9\u8c03\u8282\u6027T\u7ec6\u80de\uff08Tregs\uff09\u836f\u7269\u7684\u80bf\u7624\u514d\u75ab\u5b66\u533b\u836f\u516c\u53f8Tusk Therapeutics<\/strong>\u3002\u8fd9\u662f\u7f57\u6c0f\u7ee7<\/span><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDA5NTIxNQ==&amp;mid=2649970454&amp;idx=1&amp;sn=43cfc04cfbef3e2b942a4a6009a9e03b&amp;chksm=82e9d196b59e5880917bf14d64ed0c882891b41a4b54a569ec887f67d6485d07a08458a0ef56&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"text-decoration: underline;font-size: 15px;color: rgb(0, 112, 192);\"><span style=\"font-size: 15px;color: rgb(0, 112, 192);\">Flatiron<\/span><\/a><span style=\"font-size: 15px;\">\u548c<\/span><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzAwMDA5NTIxNQ==&amp;mid=2649974341&amp;idx=1&amp;sn=9a4863372a97ef636d39caae8f3d2db4&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"text-decoration: underline;font-size: 15px;color: rgb(0, 112, 192);\"><span style=\"font-size: 15px;color: rgb(0, 112, 192);\">Foundation Medicine<\/span><\/a><span style=\"font-size: 15px;\">\u540e\u7684\u518d\u4e00\u6b21\u6536\u8d2d\uff0c\u4e5f\u5c06\u6210\u4e3a\u80bf\u7624\u514d\u75ab\u5b66\u9886\u57df\u5185\u53c8\u4e00\u5f15\u4eba\u6ce8\u76ee\u7684\u6536\u8d2d\u9879\u76ee\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: center;\"><img class=\"\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/2-1538272809.jpg\" alt=\"\u901f\u9012 | 7.85\u4ebf\u7f8e\u5143\uff0c\u7f57\u6c0f\u91cd\u8d44\u62d3\u5c55\u80bf\u7624\u514d\u75ab\u7597\u6cd5\" title=\"\u901f\u9012 | 7.85\u4ebf\u7f8e\u5143\uff0c\u7f57\u6c0f\u91cd\u8d44\u62d3\u5c55\u80bf\u7624\u514d\u75ab\u7597\u6cd5\"  \/><\/p>\n<p style=\"text-align: center;\"><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">Tusk\u662f\u4f4d\u4e8e\u82f1\u56fd\u65af\u8482\u592b\u5c3c\u5947\u5e02\u7684\u4e00\u5bb6\u80bf\u7624\u514d\u75ab\u5b66\u533b\u836f\u516c\u53f8\uff0c\u4e8e2014\u5e74\u521b\u7acb\uff0c\u4e13\u6ce8\u4e8e\u53d1\u73b0\u4e0e\u53d1\u5c55\u53ef\u4ee5\u5f15\u5bfc\u514d\u75ab\u7cfb\u7edf\u5bf9\u6297\u764c\u7ec6\u80de\u7684\u521b\u65b0\u6297\u4f53\u836f\u7269\u3002Tusk\u7684\u6218\u7565\u4f19\u4f34\u5305\u62ec\u82f1\u56fd\u764c\u75c7\u7814\u7a76\u4e2d\u5fc3\uff08Cancer Research UK\uff0cCRUK\uff09\u65d7\u4e0b\u7684Cancer Research Technology\u4e0e\u4f26\u6566\u5927\u5b66\u5b66\u9662\uff08UCL\uff09\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u8be5\u516c\u53f8\u76ee\u524d\u6b63\u5728\u7814\u53d1<strong>\u53ef\u4ee5\u6d88\u9664\u8c03\u8282\u6027T\u7ec6\u80de\uff08Tregs\uff09\u7684\u6297\u4f53\u836f\u7269\uff0c\u5176\u4e3b\u8981\u9879\u76ee\u7684\u9776\u70b9\u4e3aCD25\u4e0eCD38\u3002<\/strong>Tregs\u7684\u4f5c\u7528\u901a\u5e38\u4e3a\u6291\u5236\u673a\u4f53\u514d\u75ab\u53cd\u5e94\uff0c\u4ece\u800c\u9884\u9632\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3002\u4f46\u5728\u53e6\u4e00\u65b9\u9762\uff0cTregs\u4e5f\u53ef\u80fd\u4f1a\u9650\u5236\u514d\u75ab\u7cfb\u7edf\u8bc6\u522b\u53ca\u5bf9\u6297\u764c\u7ec6\u80de\u3002Tusk\u7684\u4e34\u5e8a\u524d\u7814\u7a76\u6570\u636e\u663e\u793a\uff0c\u6d88\u9664\u80bf\u7624\u5fae\u73af\u5883\u91cc\u7684Tregs\u53ef\u4ee5\u589e\u5f3a\u6216\u4fee\u590d\u6297\u80bf\u7624\u514d\u75ab\u53cd\u5e94\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: center;\"><img class=\"\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/10-1538272810.jpg\" alt=\"\u901f\u9012 | 7.85\u4ebf\u7f8e\u5143\uff0c\u7f57\u6c0f\u91cd\u8d44\u62d3\u5c55\u80bf\u7624\u514d\u75ab\u7597\u6cd5\" title=\"\u901f\u9012 | 7.85\u4ebf\u7f8e\u5143\uff0c\u7f57\u6c0f\u91cd\u8d44\u62d3\u5c55\u80bf\u7624\u514d\u75ab\u7597\u6cd5\"  \/><\/p>\n<p style=\"text-align: center;\"><strong><span style=\"font-size: 14px;color: rgb(0, 112, 192);\"><span style=\"font-size: 14px;font-family: \u5fae\u8f6f\u96c5\u9ed1;font-weight: bold;\">\u25b2<\/span>Tusk\u516c\u53f8\u7684\u836f\u7269\u7814\u53d1\u7ba1\u7ebf\uff08\u56fe\u7247\u6765\u6e90\uff1aTusk\u516c\u53f8\u5b98\u7f51\uff09<\/span><\/strong><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">Tusk\u5728\u7814\u7684\u6297\u4f53\u836f\u7269\u6b63\u662f\u53ef\u4ee5\u6d88\u9664\u8fd9\u4e9b\u6709\u5bb3Tregs\u4f46\u4e0d\u5f71\u54cd\u5176\u4ed6\u514d\u75ab\u7ec6\u80de\u5bf9\u6297\u764c\u7ec6\u80de\u7684\u521b\u65b0\u836f\u7269\u3002\u9776\u5411CD25\u7684\u6297\u4f53\u662f\u4e00\u6b3e\u53ef\u4ee5\u6d88\u9664Tregs\u7684\u836f\u7269\uff0c\u5e76\u5728\u4e34\u5e8a\u524d\u7814\u7a76\u4e2d\u83b7\u5f97\u4e86\u826f\u597d\u7684\u6982\u5ff5\u9a8c\u8bc1\u7ed3\u679c\u3002\u8be5\u836f\u53ef\u4ee5\u4f5c\u4e3a\u5355\u836f\u4f7f\u7528\uff0c\u4e5f\u53ef\u4ee5\u4e0ePD-1\u548cPD-L1\u6291\u5236\u5242\u8054\u5408\u4f7f\u7528\u3002<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u9776\u5411<\/span><span style=\"font-size: 15px;\">CD38\u7684\u6297\u4f53\u662f\u4e00\u6b3e\u521b\u65b0\u514d\u75ab\u68c0\u67e5\u70b9\u836f\u7269\uff0c\u5e76\u4e14\u5f88\u6709\u53ef\u80fd\u7ee7PD-1\u4e0ePD-L1\u6291\u5236\u5242\u4e4b\u540e\u6210\u4e3a\u672a\u6765\u80bf\u7624\u514d\u75ab\u5b66\u7597\u6cd5\u7684\u652f\u67f1\u4e4b\u4e00\u3002\u5230\u76ee\u524d\u4e3a\u6b62\uff0c\u8be5\u6297\u4f53\u9488\u5bf9\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u5df2\u663e\u793a\u51fa\u826f\u597d\u6548\u679c\uff0c\u4e0b\u4e00\u6b65\u5c06\u9488\u5bf9\u5b9e\u4f53\u7624\u5f00\u5c55\u8bd5\u9a8c\u3002Tusk\u9884\u8ba1\u4e8e2019\u5e74\u5e95\u5f00\u5c55\u9488\u5bf9\u764c\u75c7\u60a3\u8005\u7684\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">Tusk\u516c\u53f8\u9996\u5e2d\u6267\u884c\u5b98Luc Dochez\u5148\u751f\u8bf4\uff1a\u201c\u6211\u4eec\u5f88\u9ad8\u5174\u770b\u5230\u7f57\u6c0f\u5c06\u7ee7\u7eed\u7814\u53d1\u8fd9\u4e00\u521b\u65b0\u6297\u4f53\u836f\u7269\u3002\u6211\u4eec\u7684\u5176\u4ed6\u80bf\u7624\u514d\u75ab\u5b66\u9879\u76ee\u5c06\u7531Tusk\u65b0\u7ec4\u5efa\u7684Black Belt Therapeutics\u516c\u53f8\u7ee7\u7eed\u8fdb\u884c\u7814\u53d1\u3002\u201d<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u6211\u4eec\u671f\u5f85\u672c\u6b21\u6536\u8d2d\u80fd\u66f4\u597d\u5730\u52a0\u901f\u521b\u65b0\u80bf\u7624\u514d\u75ab\u5b66\u7597\u6cd5\u7684\u7814\u53d1\uff0c\u5e76\u65e9\u65e5\u4e3a\u764c\u75c7\u60a3\u8005\u4eec\u5e26\u6765\u65b0\u7597\u6cd5\u9009\u9879\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">\u53c2\u8003\u8d44\u6599\uff1a<\/span><\/p>\n<p style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">[1] Roche Focuses on T Regulatory Cells in $758 Million Acquisition of Tusk Therapeutics. Retrieved September 28, 2018, from https:\/\/www.biospace.com\/article\/roche-focuses-on-t-regulatory-cells-in-758-million-acquisition-of-tusk-therapeutics\/<\/span><\/p>\n<p style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">[2] Tusk Therapeutics to be acquired by Roche. Retrieved September 28, 2018, from http:\/\/www.globenewswire.com\/news-release\/2018\/09\/28\/1586258\/0\/en\/Tusk-Therapeutics-to-be-acquired-by-Roche.html<\/span><\/p>\n<p style=\"line-height: normal;\"><span style=\"font-size: 10px;color: rgb(178, 178, 178);\">[3] Tusk Therapeutics. Retrieved September 28, 2018, from https:\/\/www.tusktherapeutics.com\/<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"white-space: normal;line-height: normal;\"><span style=\"background-color: rgb(255, 255, 255);color: rgb(178, 178, 178);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 10px;letter-spacing: 0.544px;text-align: justify;\">\u672c\u6587\u6765\u81ea\u836f\u660e\u5eb7\u5fb7\u5fae\u4fe1\u56e2\u961f\uff0c\u6b22\u8fce\u8f6c\u53d1\u5230\u670b\u53cb\u5708\uff0c\u8c22\u7edd\u8f6c\u8f7d\u5230\u5176\u4ed6\u5e73\u53f0\uff1b\u5982\u6709\u5f00\u8bbe\u767d\u540d\u5355\u9700\u6c42\uff0c\u8bf7\u5728\u6587\u7ae0\u5e95\u90e8\u7559\u8a00\uff1b\u5982\u6709\u5176\u4ed6\u5408\u4f5c\u9700\u6c42\uff0c\u8bf7\u8054\u7cfbwuxi_media@wuxiapptec.com<\/span><br  \/><\/p>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;background-color: rgb(255, 255, 255);line-height: normal;box-sizing: border-box !important;overflow-wrap: break-word !important;word-break: normal !important;\"><span style=\"max-width: 100%;font-size: 10px;color: rgb(178, 178, 178);box-sizing: border-box !important;overflow-wrap: break-word !important;word-break: normal !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;word-break: normal !important;\"  \/><\/span><\/p>\n<p style=\"white-space: normal;max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;word-break: normal !important;\">\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u258e\u836f\u660e\u5eb7\u5fb7\/\u62a5\u9053 \u7f57\u6c0f\uff08Roche\uff09\u96c6\u56e2\u4eca\u65e5\u5ba3\u5e03\uff0c\u5c06\u4ee57.85\u4ebf\u7f8e\u5143\u6536\u8d2d\u4e13\u6ce8\u4e8e\u7814\u53d1\u9488\u5bf9\u8c03\u8282\u6027T\u7ec6\u80de\uff08Tregs [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":54959,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/54958"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=54958"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/54958\/revisions"}],"predecessor-version":[{"id":54962,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/54958\/revisions\/54962"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/54959"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=54958"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=54958"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=54958"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}