{"id":54999,"date":"2018-09-28T01:00:00","date_gmt":"2018-09-30T02:00:37","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/30\/%e9%80%9f%e9%80%92-4%e4%ba%bf%e7%be%8e%e5%85%83%e5%a4%a7%e6%89%8b%e7%ac%94%ef%bc%81alexion%e6%94%b6%e8%8e%b72%e6%9c%9f%e5%9c%a8%e7%a0%94%e6%96%b0%e8%8d%af\/"},"modified":"2018-09-30T10:00:38","modified_gmt":"2018-09-30T02:00:38","slug":"%e9%80%9f%e9%80%92-4%e4%ba%bf%e7%be%8e%e5%85%83%e5%a4%a7%e6%89%8b%e7%ac%94%ef%bc%81alexion%e6%94%b6%e8%8e%b72%e6%9c%9f%e5%9c%a8%e7%a0%94%e6%96%b0%e8%8d%af","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/54999\/","title":{"rendered":"\u901f\u9012 | 4\u4ebf\u7f8e\u5143\u5927\u624b\u7b14\uff01Alexion\u6536\u83b72\u671f\u5728\u7814\u65b0\u836f"},"content":{"rendered":"
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\u258e\u836f\u660e<\/span><\/strong>\u5eb7\u5fb7\/\u62a5\u9053<\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/p>\n


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\u65e5\u524d\uff0cAlexion Pharmaceuticals\u5ba3\u5e03\u5df2\u5c31\u6536\u8d2dSyntimmune\u8fbe\u6210\u6700\u7ec8\u534f\u8bae\u3002\u6839\u636e\u534f\u8bae\u6761\u6b3e\uff0cAlexion\u5c06\u5411Syntimmune\u652f\u4ed84\u4ebf\u7f8e\u5143\u7684\u9884\u4ed8\u6b3e\uff0c\u4ee5\u53ca\u6f5c\u5728\u9ad8\u8fbe8\u4ebf\u7f8e\u5143\u7684\u989d\u5916\u91cc\u7a0b\u7891\u4ed8\u6b3e\uff0c\u603b\u6570\u989d\u9ad8\u8fbe12\u4ebf\u7f8e\u5143<\/strong>\u3002<\/span><\/p>\n

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Syntimmune\u662f\u4e00\u5bb6\u4e34\u5e8a\u9636\u6bb5\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u81f4\u529b\u4e8e\u5f00\u53d1\u9488\u5bf9\u65b0\u751f\u513fFc\u53d7\u4f53\uff08FcRn\uff09\u7684\u6297\u4f53\u6cbb\u7597\u836f\u7269\u3002\u5176\u4e3b\u8981\u5019\u9009\u4ea7\u54c1SYNT001\u662f\u4e00\u79cd\u6291\u5236FcRn\u4e0e\u514d\u75ab\u7403\u86cb\u767dG\uff08IgG\uff09\u548cIgG\u514d\u75ab\u590d\u5408\u7269\u76f8\u4e92\u4f5c\u7528\u7684\u4eba\u6e90\u5316\u5355\u514b\u9686\u6297\u4f53<\/strong>\uff0c\u6709\u671b\u80fd\u6539\u5584\u591a\u79cd\u7531IgG\u4ecb\u5bfc\u7684\u7f55\u89c1\u75c5\u7684\u6cbb\u7597\u3002SYNT001\u76ee\u524d\u6b63\u57281b\/2a\u671f\u7814\u7a76\u4e2d\u8fdb\u884c\u8bc4\u4f30\uff0c\u6cbb\u7597\u6e29\u70ed\u81ea\u8eab\u514d\u75ab\u6027\u6eb6\u8840\u6027\u8d2b\u8840\uff08WAIHA\uff09\u60a3\u8005\u548c\u5bfb\u5e38\u578b\u5929\u75b1\u75ae\uff08PV\uff09\u6216\u5929\u75b1\u75ae\uff08PF\uff09\u60a3\u8005\u3002<\/span><\/p>\n


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\"\u901f\u9012<\/p>\n

\u25b2SYNT001\u4f5c\u7528\u673a\u5236\uff08\u56fe\u7247\u6765\u6e90\uff1aSyntimmune\u5b98\u65b9\u7f51\u7ad9\uff09<\/span><\/strong><\/p>\n


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Alexion\u9996\u5e2d\u6267\u884c\u5b98Ludwig Hantson\u535a\u58eb\u8bf4\uff1a\u201c\u9776\u5411FcRn\u5728\u6cbb\u7597IgG\u4ecb\u5bfc\u7684\u75be\u75c5\u65b9\u9762\u9887\u5177\u524d\u666f\u3002SYNT001\u5728\u65e9\u671f\u4e34\u5e8a\u7814\u7a76\u4e2d\u6210\u529f\u8bc1\u660e\u4e86\u5176\u673a\u5236\u2014\u2014\u5177\u6709\u8fc5\u901f\u964d\u4f4eIgG\u6c34\u5e73\u7684\u80fd\u529b\uff0c\u5e76\u6709\u671b\u6cbb\u7597\u591a\u79cd\u7531IgG\u4ecb\u5bfc\u7684\u7f55\u89c1\u75c5\u3002\u6536\u8d2dSyntimmune\u662f\u91cd\u5efaAlexion\u7ba1\u7ebf\uff0c\u5e76\u8fdb\u4e00\u6b65\u4e30\u5bcc\u516c\u53f8\u4e34\u5e8a\u9636\u6bb5\u7f55\u89c1\u75c5\u4ea7\u54c1\u7ec4\u5408\u7684\u5173\u952e\u4e00\u6b65\u3002\u5b83\u4e0eAlexion\u73b0\u6709\u7684\u7f55\u89c1\u75c5\u7ecf\u8425\u6218\u7565\u9ad8\u5ea6\u5951\u5408\uff0c\u5e76\u63d0\u4f9b\u4e86\u8f6c\u53d8\u60a3\u8005\u62a4\u7406\u7684\u673a\u4f1a\uff0c\u6bd4\u5982\u9488\u5bf9\u6e29\u70ed\u81ea\u8eab\u514d\u75ab\u6027\u6eb6\u8840\u6027\u8d2b\u8840\uff0cSYNT001\u662f\u9996\u4e2a\u3001\u4e5f\u662f\u76ee\u524d\u4e34\u5e8a\u5f00\u53d1\u4e2d\u552f\u4e00\u7684\u6297FcRn\u7597\u6cd5<\/strong>\u3002\u201d<\/span><\/p>\n


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Syhmmune\u8463\u4e8b\u957f\u517cApple Tree Partners\u6267\u884c\u5408\u4f19\u4ebaSeth Harrison\u535a\u58eb\u8bf4\uff1a\u201c\u81ea2013\u5e74\u516c\u53f8\u6210\u7acb\u4ee5\u6765\uff0cSyntimmune\u56e2\u961f\u4e00\u76f4\u81f4\u529b\u4e8e\u4e3a\u60a3\u6709\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u60a3\u8005\u5f00\u53d1\u53d8\u9769\u7597\u6cd5\u3002SYNT001\u76ee\u524d\u6b63\u5728\u9488\u5bf9\u591a\u79cdIgG\u4ecb\u5bfc\u7684\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u8fdb\u884c\u8bc4\u4f30\uff0c\u5177\u6709\u5de8\u5927\u7684\u524d\u666f\u3002Alexion\u6240\u5c55\u793a\u7684\u7f55\u89c1\u75c5\u4e13\u4e1a\u77e5\u8bc6\u548c\u5f00\u53d1\u53ca\u63a8\u5e7f\u80fd\u529b\uff0c\u4e3aSYNT001\u7684\u6301\u7eed\u53d1\u5c55\u63d0\u4f9b\u4e86\u7406\u60f3\u7684\u57fa\u7840\u3002\u6211\u4eec\u76f8\u4fe1\uff0c\u8fd9\u5c06\u786e\u4fdd\u5176\u5e7f\u6cdb\u7684\u6f5c\u529b\u5f97\u4ee5\u5b9e\u73b0\u3002\u201d<\/span><\/p>\n


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\u53c2\u8003\u8d44\u6599\uff1a<\/span><\/p>\n

[1] Alexion to Obtain Syntimmune for $400M up Front. Retrieved September 27, 2018, from https:\/\/www.biospace.com\/article\/am6a-alexion-to-obtain-syntimmune-for-400m-up-front\/<\/span><\/p>\n

[2] Alexion Pharmaceuticals. Retrieved September 27, 2018, from http:\/\/alexion.com\/<\/span><\/p>\n


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\u672c\u6587\u6765\u81ea\u836f\u660e\u5eb7\u5fb7\u5fae\u4fe1\u56e2\u961f\uff0c\u6b22\u8fce\u8f6c\u53d1\u5230\u670b\u53cb\u5708\uff0c\u8c22\u7edd\u8f6c\u8f7d\u5230\u5176\u4ed6\u5e73\u53f0\uff1b\u5982\u6709\u5f00\u8bbe\u767d\u540d\u5355\u9700\u6c42\uff0c\u8bf7\u5728\u6587\u7ae0\u5e95\u90e8\u7559\u8a00\uff1b\u5982\u6709\u5176\u4ed6\u5408\u4f5c\u9700\u6c42\uff0c\u8bf7\u8054\u7cfbwuxi_media@wuxiapptec.com<\/span>
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