{"id":55168,"date":"2018-09-28T01:00:00","date_gmt":"2018-09-30T02:02:19","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/30\/%e7%9b%98%e7%82%b9%e8%a7%a3%e6%9e%90%ef%bc%9acar-t%e9%a3%8e%e6%bd%ae%e7%9a%84%e5%8f%91%e5%b1%95\/"},"modified":"2018-09-30T10:02:23","modified_gmt":"2018-09-30T02:02:23","slug":"%e7%9b%98%e7%82%b9%e8%a7%a3%e6%9e%90%ef%bc%9acar-t%e9%a3%8e%e6%bd%ae%e7%9a%84%e5%8f%91%e5%b1%95","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/55168\/","title":{"rendered":"\u76d8\u70b9&\u89e3\u6790\uff1aCAR-T\u98ce\u6f6e\u7684\u53d1\u5c55"},"content":{"rendered":"
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\"\u76d8\u70b9&\u89e3\u6790\uff1aCAR-T\u98ce\u6f6e\u7684\u53d1\u5c55\"<\/p>\n


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CAR-T (chimeric antigen receptor, CAR)\u7597\u6cd5\uff0c\u5168\u79f0\u4e3a\u5d4c\u5408\u6297\u539f\u53d7\u4f53T\u7ec6\u80de\u7597\u6cd5\uff0c\u662f\u901a\u8fc7\u5728T\u7ec6\u80de\u8868\u9762\u8868\u8fbe\u5d4c\u5408\u6297\u539f\u53d7\u4f53\uff0c\u6539\u53d8\u6dcb\u5df4\u7ec6\u80de\u7684\u7279\u5f02\u6027\u548c\u529f\u80fd\uff0c\u4ece\u800c\u8fbe\u5230\u7279\u5f02\u6027\u6740\u4f24\u80bf\u7624\u7684\u76ee\u7684\u3002<\/span><\/p>\n


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\"\u76d8\u70b9&\u89e3\u6790\uff1aCAR-T\u98ce\u6f6e\u7684\u53d1\u5c55\"<\/p>\n

\u56fe1 CAR-T\u539f\u7406\u548c\u5de5\u4f5c\u6d41\u7a0b<\/span><\/p>\n

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\u4eba\u4f53\u5185\u7684\u7279\u5f02\u6027\u514d\u75ab\uff0c\u6839\u636e\u4f5c\u7528\u65b9\u5f0f\u4e0d\u540c\u5206\u4e3a\u4f53\u6db2\u514d\u75ab\u548c\u7ec6\u80de\u514d\u75ab\u3002\u7ec6\u80de\u514d\u75ab\u5728\u80bf\u7624\u514d\u75ab\u4e2d\u53d1\u6325\u7740\u91cd\u8981\u7684\u4f5c\u7528\uff0cT\u7ec6\u80de\u4ee5HLA(\u4eba\u7c7b\u767d\u7ec6\u80de\u6297\u539f)\u4f9d\u8d56\u7684\u65b9\u5f0f\u8bc6\u522b\u80bf\u7624\u6297\u539f\uff0c\u8fd9\u662fT\u7ec6\u80de\u6fc0\u6d3b\u7684\u5173\u952e\u3002<\/span><\/p>\n

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\u80bf\u7624\u7ec6\u80de\u80fd\u591f\u964d\u4f4e\u6297\u539f\u7684\u8868\u8fbe\u7b49\u65b9\u5f0f\uff0c\u4f7f\u5f97T\u7ec6\u80de\u65e0\u6cd5\u901a\u8fc7HLA\u4f9d\u8d56\u7684\u65b9\u5f0f\u88ab\u6fc0\u6d3b\uff0c\u4ece\u800c\u80bf\u7624\u80fd\u591f\u8fbe\u5230\u514d\u75ab\u9003\u9038\uff0c\u8fdb\u800c\u53d1\u5c55\u6210\u6076\u6027\u80bf\u7624\u3002<\/span><\/p>\n

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CAR-T\u7597\u6cd5\u5c31\u662f\u901a\u8fc7\u751f\u7269\u6280\u672f\u624b\u6bb5\uff0c\u5728T\u7ec6\u80de\u8868\u8fbe\u51fa\u80fd\u591f\u7279\u5f02\u6027\u8bc6\u522b\u80bf\u7624\u6297\u539f\u7684\u6297\u4f53\uff0c\u4ece\u800c\u80fd\u591f\u6fc0\u6d3b\u4eba\u4f53\u514d\u75ab\u7cfb\u7edf\u5bf9\u4e8e\u80bf\u7624\u7ec6\u80de\u7684\u6740\u4f24\u3002\u7531\u4e8eCAR-T\u7597\u6cd5\u7684\u9ad8\u7075\u654f\u5ea6\uff0c\u548c\u4f20\u7edf\u6297\u4f53\u836f\u7269\u76f8\u6bd4\uff0c\u9776\u5411\/\u8131\u9776\u6bd2\u6027\u4f1a\u5bfc\u81f4\u66f4\u4e3a\u4e25\u91cd\u7684\u6bd2\u526f\u4f5c\u7528\uff0c\u56e0\u6b64\uff0cCAR-T\u6cbb\u7597\u7684\u9776\u70b9\u9700\u8981\u5bfb\u627e\u66f4\u4e3a\u4e25\u683c\u7684\u80bf\u7624\u7279\u5f02\u6027\u6297\u539f\u4f5c\u4e3a\u9776\u70b9\u3002\u8fd9\u4e2a\u9776\u70b9\u6700\u597d\u5728\u6240\u6709\u80bf\u7624\u7ec6\u80de\u8868\u9762\u8868\u8fbe\uff0c\u4f46\u662f\u81f3\u5c11\u4e0d\u5728\u91cd\u8981\u7684\u6b63\u5e38\u7ec6\u80de\u4e2d\u8868\u8fbe\u3002<\/strong><\/span><\/p>\n

 <\/span><\/p>\n

CD19\u56e0\u4e3a\u5728\u5927\u591a\u767d\u8840\u75c5\u548c\u6dcb\u5df4\u7624\u7684\u80bf\u7624\u7ec6\u80de\u8868\u9762\u9ad8\u5ea6\u8868\u8fbe\u800c\u6210\u4e3a\u4e00\u4e2a\u6709\u6f5c\u529b\u7684\u9776\u70b9\u3002\u9776\u5411CD19\u4e5f\u6210\u4e3a\u8be5\u9886\u57df\u6700\u4e3a\u706b\u70ed\u7684\u9776\u70b9\u3002\u9664\u6b64\u4e4b\u5916\uff0c\u8fd8\u5305\u62ec\u4e86HER2+\u3001BCMA\u7b49\u4f5c\u7528\u9776\u6807\u3002<\/span><\/p>\n

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\u6279\u51c6\u4e0a\u5e02\u60c5\u51b5<\/span><\/strong><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\u88681 CAR-T\u4e0a\u5e02\u4ea7\u54c1<\/span><\/strong><\/p>\n

\"\u76d8\u70b9&\u89e3\u6790\uff1aCAR-T\u98ce\u6f6e\u7684\u53d1\u5c55\"<\/strong><\/p>\n


<\/strong><\/p>\n

\u4e24\u4e2aCAR-T\u4ea7\u54c1\u90fd\u662f\u9488\u5bf9\u4e8eCD19\u9776\u70b9\u800c\u7814\u53d1\u51fa\u6765\u4e86\u3002\u4e0d\u8fc7\u7531\u4e8eCD19\u5728\u6b63\u5e38\u7684B\u7ec6\u80de\u4e5f\u4f1a\u6709\u8868\u8fbe\uff0c\u56e0\u6b64\u4f1a\u6709B\u7ec6\u80de\u53d1\u80b2\u4e0d\u826f\u7684\u526f\u4f5c\u7528\u3002<\/span>
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CAR-T\u5de5\u4f5c\u539f\u7406\u548c\u53d1\u5c55\u5386\u7a0b<\/strong><\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

T\u7ec6\u80de\u5bf9\u6297\u539f\u7684\u8bc6\u522b\u7531TCR-CD3\u590d\u5408\u4f53\u5b8c\u6210\u3002TCR\u7531\u03b1\u548c\u03b2\u94fe\u7ec4\u6210\uff0c\u5b83\u4eec\u7684\u7ed3\u6784\u51b3\u5b9a\u4e86TCR\u7684\u6297\u539f\u7279\u5f02\u6027\u3002CD3\u5305\u62ec\u03b3\u3001\u03b4\u3001\u03b5\u548c\u03b6\u56db\u79cd\u4e9a\u57fa\uff0c\u4f5c\u7528\u662f\u542f\u52a8T\u7ec6\u80de\u6fc0\u6d3b\u7a0b\u5e8f\u3002<\/span><\/p>\n


<\/span><\/p>\n

\"\u76d8\u70b9&\u89e3\u6790\uff1aCAR-T\u98ce\u6f6e\u7684\u53d1\u5c55\"<\/p>\n

\u56fe2 CAR\u7684\u7ed3\u6784<\/span><\/p>\n

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\u7b2c\u4e00\u4ee3\u7684CAR\u5c06CD3\u03b6\u94fe\u4e0e\u80fd\u591f\u8bc6\u522b\u6297\u539f\u7684\u6297\u4f53\u7247\u6bb5\u878d\u5408\u5728\u4e00\u8d77\uff0c\u4e0d\u8fc7\u6700\u5927\u7684\u95ee\u9898\u5728\u4e8e\u7f3a\u4e4f\u5171\u523a\u6fc0\u4fe1\u53f7\uff0c\u53ea\u542b\u6709\u6fc0\u6d3b\u53d7\u4f53<\/span><\/strong>\uff0c<\/span><\/strong>\u5982CD3\u03b6\u3002CAR-T\u7ec6\u80de\u5374\u65e0\u6cd5\u6709\u6548\u6269\u589e\uff0c\u7597\u6548\u4e0d\u4f73\u3002<\/span><\/p>\n


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\u7b2c\u4e8c\u4ee3\u7684CARs\u7ed3\u5408\u4e86\u6fc0\u6d3b\u548c\u5171\u523a\u6fc0\u4fe1\u53f7<\/span><\/strong>\uff0c<\/span><\/strong>\u5982CD28\u30014-1BB\u7b49\u3002\u5c06T\u7ec6\u80de\u6fc0\u6d3b\u7247\u6bb5(CD3z\u94fe)\u548c\u5171\u523a\u6fc0\u53d7\u4f53\u7247\u6bb5\u7ed3\u5408\u5728\u540c\u4e00\u4e2aCAR\u4e0a\uff0c\u8fd9\u79cd\u8bbe\u8ba1\u4e0d\u4f46\u53ef\u4ee5\u8ba9T\u7ec6\u80de\u80fd\u591f\u8bc6\u522b\u7279\u5b9a\u6297\u539f\uff0c\u800c\u4e14\u53ef\u4ee5\u5206\u6ccc\u767d\u4ecb\u7d20-2  \u5e76\u4e14\u5728\u91cd\u590d\u63a5\u89e6\u6297\u539f\u540e\u5206\u88c2\u589e\u6b96\u3002<\/span><\/p>\n

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\u7b2c\u4e09\u4ee3CARs\u7ed3\u5408\u4e86\u4e24\u4e2a\u5171\u523a\u6fc0\u548c\u6fc0\u6d3b\u4fe1\u53f7<\/span><\/strong>\u3002<\/span><\/strong>\u8fd9\u4e2a\u8bbe\u8ba1\u4e3b\u8981\u662f\u4e3a\u4e86\u5f25\u8865\u7b2c\u4e8c\u4ee3CAR\u5728T\u7ec6\u80de\u589e\u6b96\u548c\u6301\u7eed\u6027\u65e0\u6cd5\u517c\u5907\u7684\u95ee\u9898\u3002\u57fa\u4e8eCD-28\u7684CAR\u867d\u80fd\u591f\u8bf1\u5bfc\u6d3b\u8dc3\u7684T\u7ec6\u80de\u589e\u6b96\uff0c\u4f46\u662fT\u7ec6\u80de\u6301\u7eed\u6027\u6709\u9650\u3002\u800c\u57fa\u4e8e4-1BB\u7684CARs\u8bf1\u5bfc\u6548\u5e94T\u7ec6\u80de\u7684\u80fd\u529b\u76f8\u5bf9\u8f83\u4f4e\uff0c\u4f46\u662fT\u7ec6\u80de\u6301\u7eed\u6027\u6548\u679c\u66f4\u597d\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u7b2c\u56db\u4ee3CARs\u5728\u4fdd\u7559\u4e86\u7b2c\u4e09\u4ee3\u4e24\u4e2a\u5171\u523a\u6fc0\u548c\u6fc0\u6d3b\u4fe1\u53f7\u7684\u57fa\u7840\u4e0a\uff0c\u8fd8\u8fdb\u4e00\u6b65\u5f15\u5165\u4e86\u5206\u6ccc\u7ec6\u80de\u56e0\u5b50\u7684\u57fa\u56e0\u3002<\/span><\/strong>\u7b2c\u56db\u4ee3\u542b\u6709CAR\u7684T\u7ec6\u80de\u88ab\u79f0\u4e3a\u201cTRUCK\u201d\u7ec6\u80de\uff0c\u53ef\u4ee5\u5728\u6fc0\u6d3b\u7684\u540c\u65f6\uff0c\u5206\u6ccc\u7ec6\u80de\u56e0\u5b50\u3002<\/span><\/p>\n


<\/span><\/p>\n

\"\u76d8\u70b9&\u89e3\u6790\uff1aCAR-T\u98ce\u6f6e\u7684\u53d1\u5c55\"<\/p>\n

\u56fe3 CAR-T\u6280\u672f\u7684\u53d1\u5c55\u5386\u7a0b<\/span><\/p>\n

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\u65b0\u5174\u7684\u7b2c\u4e09\u3001\u56db\u4ee3CAR-T\u53d1\u5c55\u65f6\u95f4\u4e0d\u957f\uff0c\u5728\u6280\u672f\u4e0a\u8fd8\u9700\u8981\u6709\u6240\u6539\u8fdb\uff0c\u76ee\u524d\u7b2c\u4e8c\u4ee3CAR-T\u6280\u672f\u4f9d\u65e7\u662f\u4e34\u5e8a\u7814\u53d1\u7684\u4e3b\u6d41\uff0c\u5728\u6cbb\u7597\u590d\u53d1\u6027B\u7ec6\u80de\u764c\u53d8\u7684\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u53d6\u5f97\u4e86\u663e\u8457\u7684\u4e34\u5e8a\u6548\u679c\u3002<\/span><\/p>\n

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\u4e34\u5e8a\u6700\u65b0\u8fdb\u5c55<\/span><\/strong><\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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CAR-T\u7597\u6cd5\u51ed\u501f\u5728\u8840\u6db2\u7624\u975e\u5e38\u9ad8\u7684\u54cd\u5e94\u7387\uff0c\u6210\u4e3a\u4e86\u4f17\u591a\u836f\u4f01\u7814\u53d1\u7684\u7126\u70b9\uff0c\u5e02\u573a\u7684\u65b0\u8d35\u3002\u622a\u6b62\u5230\u76ee\u524d\u4e3a\u6b62\uff0c\u9664\u4e86\u8bfa\u534e\u548cKite\u516c\u53f8\u7684\u4ea7\u54c1\u4e0a\u5e02\u5916\uff0c\u5927\u90e8\u5206\u90fd\u5904\u4e8e\u4e34\u5e8aI\u3001II\u671f\u9636\u6bb5\u3002<\/span><\/p>\n

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\u6839\u636e\u836f\u6e21\u6570\u636e\u663e\u793a\uff0c\u76ee\u524d\u5904\u4e8e\u4e34\u5e8aII\u9636\u6bb5\u7684CAR-T\u4ea7\u54c1\u4e00\u517126\u4e2a\uff0c\u76ee\u524d\u5904\u4e8e\u4e34\u5e8aI\u9636\u6bb5\u7684CAR-T\u4ea7\u54c1\u4e00\u517152\u4e2a\u3002<\/span><\/strong><\/span><\/p>\n


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\u9488\u5bf9\u4e8eCD19\u6297\u539f\u7684CAR-T\u4ea7\u54c1\u662f\u4e3b\u6d41\u65b9\u5411\uff0c\u5176\u6b21BCMA\u3001EGFR\u3001HER2\u7b49\u7279\u5f02\u6027\u8f83\u597d\u7684\u9776\u70b9\u4e5f\u6210\u4e3a\u4e86\u836f\u4f01\u7814\u53d1\u7684\u91cd\u70b9\u3002<\/span><\/p>\n


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\u9002\u5e94\u75c7\u65b9\u9762\uff0c\u5927\u90e8\u5206CAR-T\u4ea7\u54c1\u90fd\u662f\u9488\u5bf9\u4e8eB\u7ec6\u80de\u6dcb\u5df4\u7624\u7b49\u76f8\u5173\u8840\u6db2\u7624\u5f00\u5c55\uff0c\u4e5f\u6709\u90e8\u5206\u836f\u4f01\u9010\u6e10\u628a\u7126\u70b9\u653e\u5728\u4e86\u5b9e\u4f53\u7624\u4e0a\uff0c\u5305\u62ec\u95f4\u76ae\u7d20\u3001HER2\u3001EGFR\u7b49\u80fd\u591f\u9776\u5411\u5b9e\u4f53\u7624\u7684\u9776\u6807\u4e0a\u3002<\/span><\/p>\n

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\u88682 \u90e8\u5206\u4e34\u5e8aII\u671fCAR-T\u4ea7\u54c1<\/span><\/strong><\/p>\n

\"\u76d8\u70b9&\u89e3\u6790\uff1aCAR-T\u98ce\u6f6e\u7684\u53d1\u5c55\"<\/strong><\/p>\n


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\u88683 \u90e8\u5206\u4e34\u5e8aI\u671fCAR-T\u4ea7\u54c1<\/span>
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\"\u76d8\u70b9&\u89e3\u6790\uff1aCAR-T\u98ce\u6f6e\u7684\u53d1\u5c55\"<\/strong><\/p>\n


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CAR-T\u95ee\u9898\u53ca\u5176\u53d1\u5c55<\/span><\/strong><\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\u867d\u7136CAR-T\u7597\u6cd5\u76ee\u524d\u5728\u8840\u6db2\u7624\u8868\u73b0\u51fa\u4e86\u663e\u8457\u7684\u7597\u6548\u4f18\u52bf\uff0c\u4e0d\u8fc7\u5728\u4e34\u5e8a\u4f7f\u7528\u548c\u5e02\u573a\u6269\u5c55\u65b9\u9762\u4f9d\u65e7\u5b58\u5728\u4e0d\u5c0f\u7684\u95ee\u9898\u3002<\/span><\/p>\n

 <\/span><\/p>\n

1.CAR-T\u6cbb\u7597\u7531\u4e8e\u8fc7\u5ea6\u6fc0\u6d3b\u514d\u75ab\u7cfb\u7edf\uff0c\u5bb9\u6613\u5f15\u8d77\u8f83\u4e3a\u4e25\u91cd\u7684\u6bd2\u526f\u4f5c\u7528\uff0c\u4f8b\u5982\u6297CD19\u7684CAR-T\u7ec6\u80de\u653b\u51fb\u635f\u4f24\u6b63\u5e38B\u7ec6\u80de\uff0c\u751a\u81f3\u53ef\u5bfc\u81f4B\u7ec6\u80de\u8017\u7aed\uff0c\u4e0d\u8fc7\u9776\u5411CD19\u867d\u7136\u4f1a\u9020\u6210B\u7ec6\u80de\u53d1\u80b2\u4e0d\u826f\uff0c\u4f46\u662f\u77ed\u671f\u5185\u60a3\u8005\u53ef\u4ee5\u8010\u53d7\u3002\u56e0\u6b64\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u9700\u8981\u5bfb\u627e\u7279\u5f02\u6027\u66f4\u597d\u7684\u9776\u70b9\u3002<\/span><\/p>\n

 <\/span><\/p>\n

2.\u6cbb\u7597\u5b9e\u4f53\u7624\u65b9\u9762\uff0c\u76ee\u524d\u53d1\u73b0\u7684\u65b0\u9776\u70b9\u8fd8\u5b58\u5728\u6709\u4e0d\u540c\u7684\u7f3a\u9677\u3002<\/span><\/p>\n

 <\/span><\/p>\n

3.\u80bf\u7624\u7ec6\u80de\u9664\u4e86\u964d\u4f4e\u80bf\u7624\u6297\u539f\u7684\u8868\u8fbe\uff0c\u540c\u65f6\u8fd8\u4f1a\u5728\u80bf\u7624\u7684\u5fae\u73af\u5883\u4e2d\u6291\u5236T\u7ec6\u80de\u7684\u6d3b\u5316\uff0c\u8054\u5408PD-1\u3001BTK\u6291\u5236\u5242\u2026\u2026\u5171\u540c\u6cbb\u7597\u80bf\u7624\u4e5f\u662f\u672a\u6765\u7684\u4e00\u4e2a\u6f6e\u6d41\u3002<\/span><\/p>\n

 <\/span><\/p>\n

4.\u76ee\u524dCAR-T\u7597\u6cd5\u4f7f\u7528\u7684\u90fd\u662f\u81ea\u4f53\u7ec6\u80de\uff0c\u4e3b\u8981\u662f\u662f\u4e3a\u4e86\u9632\u6b62\u6ce8\u5165\u7684T\u7ec6\u80de\u653b\u51fb\u5bbf\u4e3b\u6216\u8005\u5bbf\u4e3b\u6392\u65a5T\u7ec6\u80de\u7597\u6cd5\uff0c\u4f46\u662f\u4f7f\u7528\u81ea\u4f53\u7ec6\u80de\u4e0d\u53ef\u907f\u514d\u5730\u5e26\u6765\u751f\u4ea7\u6d41\u7a0b\u4e0a\u7684\u56f0\u96be\u548c\u4e0d\u540c\u60a3\u8005\u4e4b\u95f4\u7684\u7597\u6548\u5dee\u5f02\u6027\u3002\u5bfb\u627e\u8fc7\u7ee7\u8f6c\u79fb\u7684\u6700\u4f73T\u7ec6\u80de\u7c7b\u578b\uff0c\u964d\u4f4e\u751f\u4ea7\u6d41\u7a0b\u548c\u6210\u672c\uff0c\u4e5f\u6210\u4e3a\u4e86\u76ee\u524d\u5de5\u827a\u7814\u7a76\u7684\u7126\u70b9\u3002<\/span><\/p>\n

 <\/span><\/p>\n

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\"\u76d8\u70b9&\u89e3\u6790\uff1aCAR-T\u98ce\u6f6e\u7684\u53d1\u5c55\"<\/section>\n<\/section>\n

\u77e5\u9053\u5417\uff1f\u65b0\u7248\u836f\u6e21App\u65b0\u6dfb\u53ef\u89c6\u5316\u529f\u80fd\uff0c\u8ba9\u4f60\u6e05\u6670\u6d1e\u5bdf\u884c\u4e1a\u6570\u636e<\/span><\/a>
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\u53ca\u65f6\u4e86\u89e3\u884c\u4e1a\u878d\u8d44\u52a8\u5411\uff0c\u505a\u806a\u660e\u7684\u51b3\u7b56\u8005<\/span><\/a>
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142\u4e2a\u5316\u836f\u64a4\u5e02\uff0c49\u4e2a\u6e90\u4e8e\u201c\u5b89\u5168\u6027\u201d\uff01<\/span><\/a>
<\/p>\n

\u5168\u7403\u7545\u9500\u836fTOP10\u7684\u9ed1\u6846\u8b66\u544a\u7b80\u8ff0<\/span><\/a>
<\/p>\n

\u5168\u90e8\u514d\u8d39\uff01\u8fd1\u671f\u836f\u6e21\u5b66\u9662\u76f4\u64ad\u8bfe\u6c47\u603b<\/span><\/a>
<\/p>\n<\/section>\n<\/section>\n


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\"\u76d8\u70b9&\u89e3\u6790\uff1aCAR-T\u98ce\u6f6e\u7684\u53d1\u5c55\"<\/span><\/a><\/p>\n

\"\u76d8\u70b9&\u89e3\u6790\uff1aCAR-T\u98ce\u6f6e\u7684\u53d1\u5c55\"<\/span><\/a><\/p>\n

\"\u76d8\u70b9&\u89e3\u6790\uff1aCAR-T\u98ce\u6f6e\u7684\u53d1\u5c55\"<\/p>\n

\"\u76d8\u70b9&\u89e3\u6790\uff1aCAR-T\u98ce\u6f6e\u7684\u53d1\u5c55\"<\/p>\n

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\u7acb\u5373\u89e3\u9501\u4f60\u7684\u638c\u4e0a\u4e13\u4e1a\u5de5\u5177\uff01<\/span><\/p>\n<\/section>\n<\/section><\/div>\n","protected":false},"excerpt":{"rendered":"

CAR-T (chimeric antigen receptor, CAR)\u7597\u6cd5\uff0c\u5168\u79f0\u4e3a\u5d4c\u5408\u6297\u539f\u53d7\u4f53T\u7ec6\u80de\u7597\u6cd5 […]<\/p>\n","protected":false},"author":1,"featured_media":55169,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/55168"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=55168"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/55168\/revisions"}],"predecessor-version":[{"id":55183,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/55168\/revisions\/55183"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/55169"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=55168"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=55168"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=55168"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}