{"id":55206,"date":"2018-09-27T01:00:00","date_gmt":"2018-09-30T02:02:39","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/30\/2018%e5%b9%b4%e9%9d%9e%e5%b0%8f%e7%bb%86%e8%83%9e%e8%82%ba%e7%99%8c%e5%b8%82%e5%9c%ba%e5%88%86%e6%9e%90%e5%92%8c%e8%b6%8b%e5%8a%bf%e8%b5%b0%e5%90%91-%e9%9d%b6%e5%90%91%e8%8d%af\/"},"modified":"2018-09-30T10:02:45","modified_gmt":"2018-09-30T02:02:45","slug":"2018%e5%b9%b4%e9%9d%9e%e5%b0%8f%e7%bb%86%e8%83%9e%e8%82%ba%e7%99%8c%e5%b8%82%e5%9c%ba%e5%88%86%e6%9e%90%e5%92%8c%e8%b6%8b%e5%8a%bf%e8%b5%b0%e5%90%91-%e9%9d%b6%e5%90%91%e8%8d%af","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/55206\/","title":{"rendered":"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p><img class=\"__bg_gif\"     width=\"auto\" style=\"font-size: 16px;white-space: normal;color: rgb(62, 62, 62);line-height: 1.75em;text-align: center;background-color: rgb(255, 255, 255);box-sizing: border-box !important;word-wrap: break-word !important;visibility: visible !important;width: auto !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/3-1538272960.gif\" alt=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\" title=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\"  \/><\/p>\n<p><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u4f5c\u4e3a\u53d1\u75c5\u7387\u548c\u6b7b\u4ea1\u6570\u76ee\u6700\u591a\u7684\u6076\u6027\u80bf\u7624\u4e4b\u4e00\u2014\u2014<\/span><span style=\"font-size: 15px;color: rgb(0, 128, 255);\"><strong>\u80ba\u764c<\/strong><\/span><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\uff0c\u6210\u4e3a\u65e0\u6570\u60a3\u8005\u7684\u68a6\u9b47\uff0c\u533b\u836f\u7814\u53d1\u7684\u7126\u70b9\uff0c\u5e02\u573a\u4e0a\u7684\u5fc5\u4e89\u4e4b\u5730\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\"><br  \/><\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u8fd9\u4e2a\u75be\u75c5\u9886\u57df\u6709\u5f88\u591a\u7cbe\u51c6\u6cbb\u7597\u65b9\u5f0f\uff0c\u8bde\u751f\u4e86\u65e0\u6570\u7684\u4f20\u5947\u836f\u7269\uff0c\u5982<\/span><span style=\"font-size: 15px;color: rgb(0, 128, 255);\"><strong>\u5965\u5e0c\u66ff\u5c3c<\/strong><\/span><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u2014\u2014\u53f2\u4e0a\u6700\u5feb\u5ba1\u6279\u4e0a\u5e02\u7684\u80bf\u7624\u836f\uff1b\u89c1\u8bc1\u4e86\u65b0\u65e7\u6cbb\u7597\u65b9\u6cd5\u7684\u4ea4\u66ff\uff0c\u9776\u5411\u65f6\u4ee3\u7684\u5174\u8d77\u3001\u514d\u75ab\u65f6\u4ee3\u7684\u65b0\u6f6e\uff1b<\/span><span style=\"font-size: 15px;\">\u76ee\u7779\u4e86\u79d1\u7814\u5de5\u4f5c\u8005\u7684\u5fc3\u8840\uff0c\u4e00\u4e8c\u4e09\u4ee3\u6fc0\u9176\u6291\u5236\u5242\uff0c\u4e0d\u65ad\u63a8\u9648\u51fa\u65b0\uff0c\u514b\u670d\u8010\u836f\u7684\u95ee\u9898\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">&nbsp;<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u80ba\u764c\u4e3b\u8981\u5206\u4e3a\u975e\u5c0f\u7ec6\u80de\u764c\u548c\u5c0f\u7ec6\u80de\u764c\u4e24\u5927\u7c7b\u578b\uff0c\u5176\u4e2d\uff0c\u975e\u5c0f\u7ec6\u80de\u764c(NSCLC)\u536085%\u4ee5\u4e0a\u3002\u4ece\u7ec4\u7ec7\u5b66\u5206\u7c7b\u6765\u770b\uff0c\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5305\u542b\uff1a\u817a\u7624\uff0c\u975e\u9cde\u72b6\u4e0a\u76ae\u764c\uff0c\u5927\u7ec6\u80de\u4e0a\u76ae\u764c\uff0c\u8089\u7624\u6837\u4e0a\u76ae\u764c\u4ee5\u53ca\u817a\u9cde\u72b6\u4e0a\u76ae\u764c\u7b49\u3002\u65e9\u671f\u7684NSCLC\u4e3b\u8981\u4f9d\u9760\u624b\u672f\u6cbb\u7597\uff0c\u4f46\u591a\u6570NSCLC\u60a3\u8005\u521d\u8bca\u65f6\u5df2\u662f\u4e2d\u665a\u671f\uff0c\u53ea\u80fd\u4ee5\u836f\u7269\u6cbb\u7597\u4e3a\u4e3b\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">&nbsp;<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u968f\u7740\u5206\u5b50\u751f\u7269\u5b66\u548c\u80bf\u7624\u514d\u75ab\u5b66\u7684\u53d1\u5c55\uff0cNSCLC\u7684\u6cbb\u7597\u4e5f\u671d\u5411\u66f4\u52a0\u7cbe\u51c6\u7684\u6cbb\u7597\u65b9\u5f0f\u3002\u4ece\u6700\u5f00\u59cb\u7684\u653e\u7597\u5316\u7597\u624b\u672f\u5230\u9776\u5411\u7ed9\u836f\u518d\u5230\u4eca\u5929\u7684\u514d\u75ab\u65f6\u4ee3\uff0c\u4e34\u5e8a\u6cbb\u7597\u4e0a\u591a\u79cd\u4e0d\u540c\u7406\u5ff5\u534f\u540c\u4f5c\u7528\u3002<\/span><span style=\"font-size: 15px;color: rgb(0, 128, 255);\"><strong>\u6839\u636e\u836f\u7269\u6cbb\u7597\u65b9\u5f0f\u7684\u4e0d\u540c\uff0c\u4e00\u5171\u5206\u4e3a\u9776\u5411\u836f\u7269\u3001\u514d\u75ab\u836f\u7269\u548c\u5316\u7597\u836f\u7269\u4e09\u4e2a\u677f\u5757\uff0c\u8fdb\u884c\u836f\u7269\u5e02\u573a\u548c\u672a\u6765\u6cbb\u7597\u8d8b\u52bf\u5206\u6790\u3002<\/strong><\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\"><br  \/><\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\"><\/span><\/p>\n<section  label=\"Powered by 135editor.com\" style=\"font-size:16px;font-family:\u5fae\u8f6f\u96c5\u9ed1;\">\n<section  label=\"Powered by 135editor.com\">\n<section class=\"_135editor\"   style=\"border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box;\">\n<section style=\"margin: 15px 0%;text-align: center;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: top;box-sizing: border-box;\">\n<section style=\"width: 45px;height: 5px;margin-left: auto;line-height: 5px;background-color: #b6e4fd;box-sizing: border-box;color: #0573af;\"><\/section>\n<section style=\"margin-top: -3px;margin-bottom: -3px;border-width: 1px;border-style: solid;border-color: #000000;padding-left: 8px;padding-right: 8px;color: #3e3e3e;letter-spacing: 0px;line-height: 1.75;box-sizing: border-box;transform: rotate(0deg);-webkit-transform: rotate(0deg);-moz-transform: rotate(0deg);-o-transform: rotate(0deg);\">\n<p style=\"box-sizing: border-box;\"><span style=\"color: #000000;\"><strong style=\"box-sizing: border-box;\" class=\"135brush\" >\u9776\u5411\u836f\u7269<\/strong><\/span><\/p>\n<\/section>\n<section style=\"width: 45px;height: 5px;line-height: 5px;background-color: #b6e4fd;box-sizing: border-box;color: #0573af;\"><br  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u76ee\u524d\uff0c\u591a\u79cd\u57fa\u56e0\u7a81\u53d8\u4e0e\u8868\u8fbe\u5f02\u5e38\u7b49\u5206\u5b50\u673a\u5236\u4e5f\u88ab\u8bc1\u5b9e\u4e0eNSCLC\u53d1\u75c5\u76f8\u5173\uff0c\u6839\u636e\u9a71\u52a8\u57fa\u56e0\u7a81\u53d8\u800c\u8bbe\u8ba1\u7684\u836f\u7269\u5c31\u662f\u76ee\u524d\u6240\u8bf4\u7684\u9776\u5411\u836f\u7269\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: normal;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\"><br  \/><\/span><\/p>\n<p style=\"text-align: center;line-height: normal;\"><strong><img class=\"\"      style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/4-1538272960.jpg\" alt=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\" title=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\"  \/><\/strong><\/p>\n<p style=\"text-align: center;line-height: 1.5em;\"><span style=\"color: rgb(136, 136, 136);\"><strong><span style=\"font-size: 14px;\">\u56fe1\uff1aNSCLC\u9a71\u52a8\u57fa\u56e0\u7a81\u53d8\u9891\u7387\u548c\u6cbb\u7597\u836f\u7269<\/span><\/strong><\/span><\/p>\n<p style=\"text-align: justify;line-height: normal;\"><span style=\"font-size: 12px;color: rgb(136, 136, 136);\">\u6ce8\uff1aNSCLC\u9a71\u52a8\u57fa\u56e0\u6291\u5236\u5242\u76ee\u524d\u53ea\u6709EGFR\u3001ALK\u3001ROS1\u4e09\u4e2a\u6709\u836f\u7269\u4e0a\u5e02\uff0c\u5176\u4e2dROS1\u5c0f\u5206\u5b50\u6291\u5236\u5242\u514b\u5511\u66ff\u5c3c\u662f\u5c5e\u4e8eALK\u3001ROS1\u591a\u9776\u70b9\u6291\u5236\u5242\uff0c\u5c5e\u4e8eALK\u6291\u5236\u5242\u8303\u7574\u3002\u5176\u4ed6\u76ee\u524d\u90fd\u6709\u836f\u7269\u8fdb\u5165\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4e0d\u8fc7\u5927\u591a\u96c6\u4e2d\u4e8e\u4e34\u5e8aII\u671f\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">&nbsp;<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u6839\u636e\u9a71\u52a8\u57fa\u56e0\u548c\u4f5c\u7528\u65b9\u5f0f\u7684\u4e0d\u540c\uff0c<\/span><span style=\"font-size: 15px;color: rgb(0, 128, 255);\"><strong>\u9776\u5411\u836f\u7269\u4e00\u822c\u53c8\u5305\u62ec\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53-\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242EGFR-TKIs\u3001\u95f4\u53d8\u6dcb\u5df4\u7624\u6fc0\u9176(ALK)\u6291\u5236\u5242\u3001\u6297\u8840\u7ba1\u751f\u6210\u5355\u6297\u836f\u7269\u3002<\/strong><\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><br  \/><\/p>\n<section  label=\"Powered by 135editor.com\" style=\"font-size:16px;font-family:\u5fae\u8f6f\u96c5\u9ed1;\">\n<section  label=\"Powered by 135editor.com\">\n<section class=\"_135editor\"   style=\"border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box;\">\n<section class=\"_135editor\"   style=\"border-width: 0px;border-style: none;border-color: initial;display: inline-block;box-sizing: border-box;\"  >\n<p style=\"margin-top: 8px;padding-right: 10px;font-weight: bold;line-height: 28px;max-width: 100%;color: rgb(0, 128, 255);min-height: 32px;border-bottom: 2px solid rgb(0, 128, 255);border-top-color: rgb(0, 128, 255);border-right-color: rgb(0, 128, 255);border-left-color: rgb(0, 128, 255);text-align: justify;\"><span class=\"autonum\" placeholder=\"1\" style=\"border-radius: 80% 100% 90% 20%;color: rgb(255, 255, 255);display: block;float: left;line-height: 20px;margin-right: 8px;max-width: 100%;padding: 4px 10px;background-color: rgb(0, 128, 255);\"  title=\"\">1<\/span><strong><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\">EGFR-TKIs<\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: justify;line-height: normal;\"><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">EGFR\u7a81\u53d8\u662fNSCLC\u6700\u5e38\u89c1\u7684\u9a71\u52a8\u57fa\u56e0\uff0c\u5927\u7ea617%\u7684NSCLC\u60a3\u8005\u53d1\u751fEGFR\u7a81\u53d8\uff0c\u4e2d\u56fd\u7b49\u4e9a\u6d32\u56fd\u5bb6\u7a81\u53d8\u6982\u7387\u9ad8\u8fbe30%\u4ee5\u4e0a\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">&nbsp;<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">EGFR-TKIs\u901a\u8fc7\u5185\u6e90\u6027\u914d\u4f53\u7ade\u4e89\u6027\u7ed3\u5408EGFR\uff0c\u6291\u5236\u916a\u6c28\u9178\u6fc0\u9176\u7684\u6d3b\u5316\uff0c\u8fdb\u800c\u963b\u65adEGFR\u4fe1\u53f7\u901a\u8def\uff0c\u6700\u7ec8\u4ea7\u751f\u6291\u5236\u80bf\u7624\u7ec6\u80de\u7684\u589e\u6b96\u3001\u8f6c\u79fb\u5e76\u4fc3\u8fdb\u80bf\u7624\u7ec6\u80de\u53d1\u751f\u51cb\u4ea1\u7b49\u4e00\u7cfb\u5217\u751f\u7269\u5b66\u6548\u5e94\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">&nbsp;<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u591a\u9879\u5927\u578bIII\u671f\u4e34\u5e8a\u8bd5\u9a8c\u8bc1\u5b9eEGFR-TKIs\u6cbb\u7597EGFR\u7a81\u53d8\u9633\u6027NSCLC\u7684\u6548\u679c\u4f18\u4e8e\u5316\u7597\uff0c\u56e0\u6b64\u51e0\u4e4e\u6240\u6709\u7684\u6307\u5357\u90fd\u63a8\u8350EGFR-TKIs(\u5982\u5409\u975e\u66ff\u5c3c\u3001\u5384\u6d1b\u66ff\u5c3c\u3001\u57c3\u514b\u66ff\u5c3c)\u4f5c\u4e3aEGFR\u7a81\u53d8\u9633\u6027NSCLC\u7684\u4e00\u7ebf\u6cbb\u7597\u65b9\u6848\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">&nbsp;<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"color: rgb(0, 128, 255);\"><strong><span style=\"font-size: 15px;\">\u6839\u636e\u4f5c\u7528\u9776\u70b9\u3001\u7ed3\u5408\u4f4d\u70b9\u3001\u6291\u5236\u673a\u5236\u4ee5\u53ca\u4e34\u5e8a\u8010\u836f\u6027\u8868\u73b0\uff0c\u4e3b\u8981\u5c06EGFR-TKIs\u5206\u4e3a\u4e09\u4ee3\u3002<\/span><\/strong><\/span><\/p>\n<p style=\"text-align: justify;line-height: normal;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\"><br  \/><\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/0-1538272960.jpg\" alt=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\" title=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\"  \/><\/p>\n<p style=\"text-align: center;line-height: normal;\"><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">EGFR\u7a81\u53d8\u4e3b\u8981\u53d1\u751f\u572818~21\u53f7\u5916\u663e\u5b50\uff0c\u5176\u4e2d19\u53f7\u5916\u663e\u5b50\u7684\u7f3a\u5931\u7a81\u53d8\u548c21\u53f7\u5916\u663e\u5b50\u7684L858R\u70b9\u7a81\u53d8\u662f\u6700\u5e38\u89c1\u7684EGFR\u7a81\u53d8\u4e9a\u578b\uff0c\u5360\u6240\u6709\u7a81\u53d8\u7c7b\u578b\u768490%\uff0c\u79f0\u4e3aEGFR\u57fa\u56e0\u7684\u654f\u611f\u7a81\u53d8\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">&nbsp;<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><strong><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u7b2c\u4e00\u4ee3EGFR-TKIs\uff0c\u9002\u7528\u4e8eEGFR\u5177\u6709\u654f\u611f\u57fa\u56e0\u7a81\u53d8\u7684\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7684\u4e00\u7ebf\u6cbb\u7597\u3002<\/span><\/strong><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u4e3b\u8981\u91c7\u7528\u4e0eATP\u7ade\u4e89\u6027\u7ed3\u5408\u7684\u65b9\u5f0f\uff0c\u5bf9\u4e8e\u572819\u53f7\u5916\u663e\u5b50\u7684\u7f3a\u5931\u7a81\u53d8\u548c21\u53f7\u5916\u663e\u5b50\u7684\u70b9\u7a81\u53d8\u7684EGFR\u8fdb\u884c\u6291\u5236\u3002\u7136\u800c\uff0c\u4e00\u4ee3EGFR-TKIs\u9664\u7ade\u4e89\u6027\u6291\u5236\u7a81\u53d8\u7684EGFR\u86cb\u767d\u5916\uff0c\u4e5f\u80fd\u6291\u5236\u6b63\u5e38\u7ec6\u80de\u7684EGFR\u529f\u80fd\uff0c\u5bfc\u81f4\u76ae\u75b9\uff0c\u8179\u6cfb\u548c\u65e0\u98df\u6b32\u7b49\u526f\u4f5c\u7528\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">&nbsp;<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u5bf9\u4e8e\u57fa\u56e0\u6d4b\u5e8f\u7b5b\u9009\u51fa\u5177\u6709EGFR\u7a81\u53d8\u7684\u60a3\u8005\uff0cEGFR-TKIs\u4e0d\u7ba1\u662f\u4e2d\u4f4d\u65e0\u8fdb\u5c55\u751f\u5b58\u671f(\u662f\u60a3\u8005\u751f\u5b58\u671f\u8d28\u91cf\u6700\u91cd\u8981\u7684\u6307\u6807)\uff0c\u8fd8\u662f\u5728\u5ba2\u89c2\u7f13\u89e3\u7387\u3001\u526f\u4f5c\u7528\u4e0a\u90fd\u4f18\u4e8e\u4f20\u7edf\u7684\u5316\u7597\u836f\u7269\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">&nbsp;<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u8fd9\u4e5f\u662f\u7cbe\u51c6\u533b\u7597\u8f83\u597d\u7684\u8be0\u91ca\uff0c\u628a\u6700\u6709\u7528\u7684\u836f\u7269\u7528\u5728\u6700\u9700\u8981\u7684\u75c5\u4eba\u4e0a\uff0c\u53ea\u6709EGFR\u7a81\u53d8\u7684\u60a3\u8005\u670d\u7528\u4e86\u624d\u80fd\u4ea7\u751f\u7597\u6548\uff0c\u8981\u4e0d\u7136\u6548\u679c\u8fd8\u4e0d\u5982\u5316\u7597\u836f\u7269\u3002\u5e9e\u5927\u7684\u80bf\u7624\u60a3\u8005\u4eba\u7fa4\u4e5f\u5e26\u6765\u4e86\u5de8\u5927\u7684\u5e02\u573a\u4ef7\u503c\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: normal;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\"><br  \/><\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/7-1538272961.jpg\" alt=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\" title=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\"  \/><\/p>\n<p style=\"text-align: center;line-height: normal;\"><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u968f\u7740\u7b2c\u4e00\u4ee3EGFR-TKIs\u4f17\u591a\u836f\u4f01\u7684\u4ecb\u5165\uff0c\u548c\u8010\u836f\u6027\u95ee\u9898\u7b49\u8bf8\u591a\u56e0\u7d20\u7684\u5b58\u5728\uff0c\u5e02\u573a\u51fa\u73b0\u75b2\u6001\uff0c\u5f00\u59cb\u8d70\u5411\u4e0b\u6ed1\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">&nbsp;<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u8981\u77e5\u9053NSCLC\u6574\u4e2a\u9886\u57df\u7684\u589e\u957f\u901f\u5ea6\u9ad8\u8fbe16%\u5de6\u53f3\uff0c\u5728\u8fd9\u4e2a\u6d6a\u6f6e\u4e0b\uff0c\u7b2c\u4e00\u4ee3EGFR-TKIs\u6216\u8bb8\u4e5f\u53ea\u80fd\u611f\u53f9\uff1a\u5915\u9633\u65e0\u9650\u597d\uff0c\u53ea\u662f\u8fd1\u9ec4\u660f\uff01<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u4e0d\u8fc7\u8fd9\u5bf9\u4e8e\u4e2d\u56fd\u7684\u60a3\u8005\u5374\u662f\u4e00\u4e2a\u798f\u97f3\uff0c\u9ad8\u8fbe30%\u7684EGFR\u7a81\u53d8\uff0c\u5e9e\u5927\u7684\u60a3\u8005\u57fa\u6570\uff0c\u8fd9\u4e9b\u4eba\u5c31\u50cf\u55f7\u55f7\u5f85\u54fa\u7684\u5a74\u513f\u4e00\u6837\u7b49\u5f85\u836f\u7269\u6765\u6551\u547d\u4e86\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u7b2c\u4e00\u9776\u5411\u836f\u7269\u867d\u7136\u7597\u6548\u663e\u8457\uff0c\u4f462\/3\u7684\u60a3\u8005\u90fd\u4f1a\u5728\u4f7f\u7528\u836f\u72691-2\u5e74\u51fa\u73b0\u6297\u836f\u6027\u3002<\/span><br  \/><\/p>\n<p style=\"text-align: justify;line-height: normal;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\"><\/span><\/p>\n<section  label=\"Powered by 135editor.com\" style=\"font-size:16px;font-family:\u5fae\u8f6f\u96c5\u9ed1;\">\n<section  label=\"Powered by 135editor.com\">\n<section class=\"_135editor\"   style=\"border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box;\">\n<section class=\"layout\" style=\"padding: 1px;border-width: 1px;border-style: solid;border-color: rgb(157, 180, 194);font-size: 14px;margin-right: auto;margin-left: auto;box-sizing: border-box;\">\n<section style=\"padding: 1px;border-width: 1px;border-style: solid;border-color: rgb(157, 180, 194);color: inherit;box-sizing: border-box;\">\n<section class=\"135brush\"  style=\"padding: 15px;border-width: 1px;border-style: solid;border-color: rgb(157, 180, 194);color: inherit;box-sizing: border-box;\">\n<p style=\"font-family: Helvetica, Arial, sans-serif;font-size: medium;text-align: justify;line-height: 1.75em;\"><strong><span style=\"font-size: 15px;\">\u8010\u836f\u673a\u5236\uff1a<\/span><\/strong><\/p>\n<p style=\"font-family: Helvetica, Arial, sans-serif;font-size: medium;text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u2460&nbsp;&nbsp;&nbsp;\u4e00\u4ee3EGFR-TKIs\u7ed3\u5408\u7684\u6c28\u57fa\u9178\u7247\u6bb5\u53d1\u751f\u4e86T790M\u7a81\u53d8\uff0c\u5bfc\u81f4\u8010\u836f\uff0c\u5360\u6bd4\u4e3a50%\u3002<\/span><\/p>\n<p style=\"font-family: Helvetica, Arial, sans-serif;font-size: medium;text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u2461&nbsp;&nbsp;&nbsp;\u80bf\u7624\u7ec6\u80de\u53ef\u4ee5\u5176\u4ed6\u4ee3\u8c22\u901a\u8def\u6765\u5f25\u8865EGFR\u7a81\u53d8\u88ab\u6291\u5236\uff0c\u53ef\u4ee5\u901a\u8fc7c-Met\u3001HER2\u3001KRAS\u7b49\u901a\u8def\uff0c\u5360\u6bd4\u4e3a20%\u3002<\/span><\/p>\n<p style=\"font-family: Helvetica, Arial, sans-serif;font-size: medium;text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u2462&nbsp;&nbsp;&nbsp;\u76ee\u524d\u8fd8\u6ca1\u6709\u5360\u5230\u51c6\u786e\u7684\u8010\u836f\u673a\u5236\uff0c\u5360\u6bd430%\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section  class=\"_135editor\" style=\"border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box;\">\n<p><br  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u56e0\u6b64\u6839\u636e\u4e00\u4ee3\u836f\u7269\u5bfc\u81f4E790M\u7a81\u53d8\u7684\u60c5\u51b5\uff0c\u53c8\u5f00\u53d1\u4e86\u4e8c\u3001\u4e09\u4ee3EGFR-TKIs\uff0c\u4e0d\u8fc7\u53ea\u6709\u7b2c\u4e09\u4ee3EGFR-TKIs\u80fd\u591f\u5bf9E790M\u7a81\u53d8\u7684\u60a3\u8005\u6709\u54cd\u5e94\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u7b2c\u4e8c\u4ee3\u5f00\u53d1\u7684\u903b\u8f91\u662f\uff1a\u5982\u679c\u836f\u6548\u66f4\u597d\uff0c\u6216\u8bb8\u8010\u836f\u6027\u4f1a\u51fa\u73b0\u66f4\u665a\uff0c\u751a\u81f3\u662f\u6ca1\u6709\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><strong><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u7b2c\u4e8c\u4ee3EGFR-TKIs\u963f\u6cd5\u66ff\u5c3c\u91c7\u7528\u5171\u4ef7\u952e\u7ed3\u5408\u7684\u65b9\u5f0f\u5bf9EGFR\u8fdb\u884c\u4e0d\u53ef\u9006\u7684\u6291\u5236\uff0c\u540c\u65f6\u5bf9HER2\u6709\u90e8\u5206\u7684\u6291\u5236\u4f5c\u7528\u3002<\/span><\/strong><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u7531\u4e8e\u963f\u6cd5\u66ff\u5c3c\u4e0eEGFR\u916a\u6c28\u9178\u6fc0\u9176\u533a\u7684\u7ed3\u5408\u662f\u4e0d\u53ef\u9006\u6027\u7684\uff0c\u56e0\u6b64\u963f\u6cd5\u66ff\u5c3c\u7684\u4f5c\u7528\u5f3a\u5ea6\u66f4\u5927\uff0c\u4e0d\u8fc7\u4e5f\u5bfc\u81f4\u5b83\u548c\u6b63\u5e38\u7ec6\u80de\u7684EGFR\u4f5c\u7528\u66f4\u5f3a\uff0c\u526f\u4f5c\u7528\u4e5f\u66f4\u4e3a\u5267\u70c8\u3002\u56e0\u6b64\u963f\u6cd5\u66ff\u5c3c\u5728\u4e34\u5e8a\u4f7f\u7528\u8fdc\u6ca1\u6709\u8fbe\u5230\u5927\u5bb6\u7684\u671f\u671b\uff0c\u5e02\u573a\u8868\u73b0\u4e0a\u4e5f\u7b97\u4e2d\u89c4\u4e2d\u77e9\uff0c\u73b0\u5728\u5904\u4e8e\u4e00\u4e2a\u7f13\u6162\u722c\u5761\u589e\u957f\u9636\u6bb5\u3002\u800c18\u5e747\u6708\u4efd17\u53f7\u521a\u4e0a\u5e02\u7684\u8fbe\u514b\u66ff\u5c3c\u6216\u8bb8\u53ef\u4ee5\u4e3a\u5176\u4e8c\u4ee3EGFR-TKIs\u8bc1\u660e\uff0c\u5728\u4e00\u7ebfEGFR\u9633\u6027\u7684NSCLC\u6709\u6240\u4f5c\u4e3a\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\"><br  \/><\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><strong><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u4e09\u4ee3EGFR-TKIs\u5c31\u5728\u5de8\u5927\u7684\u9700\u6c42\u548c\u77a9\u76ee\u4e0b\u5e94\u8fd0\u800c\u751f\uff0c\u8fdb\u4e00\u6b65\u5f00\u8f9f\u4e86\u201c\u7cbe\u51c6\u533b\u7597\u201d\u7684\u65f6\u4ee3\u3002<\/span><\/strong><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\"><br  \/><\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u4e00\u4ee3EGFR\u7528\u836f\u4ea7\u751f\u8010\u836f\u540e\uff0c\u4e00\u7ebf\u7684\u7528\u836f\u662f\u5316\u7597\u836f\u7269\uff0c\u57fa\u672c\u4e0a\u53c8\u56de\u5230\u4e86\u6700\u5f00\u59cb\u201c\u65e0\u836f\u53ef\u6551\u201d\u7684\u5730\u6b65\u4e86\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"color: rgb(0, 128, 255);\"><strong><span style=\"font-size: 15px;\">AZD9291(\u5965\u5e0c\u66ff\u5c3c)\u662f\u4e00\u79cd\u53e3\u670d\u7684\u5c0f\u5206\u5b50\u7b2c\u4e09\u4ee3EGFR-TKI\uff0c\u662f\u9996\u4e2a\u9488\u5bf9EGFR T790M\u7a81\u53d8\u7684\u80ba\u764c\u836f\u7269\uff0c<\/span><\/strong><\/span><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u80fd\u9776\u5411\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7684EGFR\u57fa\u56e0\u7a81\u53d8(\u5305\u62ec18\uff0c19\uff0c21\u7a81\u53d8)\u548cEGFR-TKI\u83b7\u5f97\u6027\u8010\u836f(T790M)\u3002\u5965\u5e0c\u66ff\u5c3c\u80fd\u591f\u626e\u6f14\u8005\u7b2c\u4e00\u3001\u4e8c\u4ee3EGFR-TK\uff0c\u9776\u5411EGFR\u57fa\u56e0\u7a81\u53d8(\u5305\u62ec18\uff0c19\uff0c21\u7a81\u53d8)\uff0c\u4f5c\u7528\u7a0d\u5f31\uff1b\u53c8\u80fd\u591f\u9776\u5411T790M\u7a81\u53d8\uff0c\u626e\u6f14\u4e09\u4ee3EGFR-TKI\u7684\u89d2\u8272\uff1b\u540c\u65f6\u5965\u5e0c\u66ff\u5c3c\u5177\u6709\u66f4\u597d\u7684\u9009\u62e9\u6027\uff0c\u5bf9\u91ce\u751f\u578b\u7684EGFR\u86cb\u767d\u4f5c\u7528\u5f31\uff1b\u800c\u6700\u4e3a\u5173\u952e\u7684\u662f\uff0c\u5b83\u8fd8\u5bf9\u4e8e\u8111\u8f6c\u79fb\u6709\u6548\u300250%\u7684NSCLC\u60a3\u8005\u90fd\u4f1a\u53d1\u751f\u80bf\u7624\u7684\u8111\u8f6c\u79fb\uff0c\u800c\u4e4b\u524d\u7684EGFR\u6291\u5236\u5242\u90fd\u4e0d\u80fd\u6709\u6548\u901a\u8fc7\u8840\u8111\u5c4f\u969c\uff0c\u8fbe\u5230\u6740\u4f24\u80bf\u7624\u7684\u4f5c\u7528\u3002<\/span><\/p>\n<section  label=\"Powered by 135editor.com\" style=\"font-size:16px;font-family:\u5fae\u8f6f\u96c5\u9ed1;\">\n<section  label=\"Powered by 135editor.com\">\n<section class=\"_135editor\"   style=\"border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box;\">\n<section class=\"135brush\" style=\"margin-top: 10px;padding: 15px;color: rgb(123, 123, 111);text-align: justify;background-color: rgb(245, 245, 244);box-sizing: border-box;\">\n<p style=\"line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u7b80\u5355\u6765\u8bf4\uff1a\u526f\u4f5c\u7528\u5c0f\u3001\u7597\u6548\u597d\u3001\u76ee\u6807\u4eba\u7fa4\u7cbe\u51c6\u3001\u8fd8\u6709\u9644\u52a0\u4f5c\u7528\uff0c\u72ec\u6b64\u4e00\u5bb6\u6ca1\u6709\u5bf9\u624b\u3002<\/span><\/p>\n<\/section>\n<section style=\"height: 20px;background-image: url('http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/1-1538272965.png');background-size: 50% 100%;background-repeat: no-repeat;\"><\/section>\n<\/section>\n<section  class=\"_135editor\" style=\"border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box;\">\n<p style=\"text-align: center;line-height: normal;\"><img class=\"\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/10-1538272961.jpeg\" alt=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\" title=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: center;line-height: normal;\"><span style=\"font-size: 14px;\"><strong><span style=\"color: rgb(136, 136, 136);\">\u56fe2\uff1a\u5965\u5e0c\u66ff\u5c3c\u4e34\u5e8a\u8bd5\u9a8c<\/span><\/strong><\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\"><\/span><\/p>\n<section  label=\"Powered by 135editor.com\" style=\"font-size:16px;font-family:\u5fae\u8f6f\u96c5\u9ed1;\">\n<section  label=\"Powered by 135editor.com\">\n<section class=\"_135editor\"   style=\"border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box;\">\n<section  class=\"_135editor\" style=\"border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box;\"  >\n<section class=\"_editor\" >\n<section style=\"width: 20px;height: 2px;background-color: rgb(0, 128, 255);border-radius: 10px;opacity: 0.3;color: rgb(255, 255, 255);box-sizing: border-box;\"><\/section>\n<section style=\"width: 40px;height: 2px;background-color: rgb(0, 128, 255);margin-top: 3px;border-radius: 10px;opacity: 0.6;color: rgb(255, 255, 255);box-sizing: border-box;\"><\/section>\n<section style=\"height: 2px;background-color: rgb(0, 128, 255);margin-top: 3px;border-radius: 10px;color: rgb(255, 255, 255);box-sizing: border-box;\"><\/section>\n<section class=\"135brush\" style=\"font-size: 14px;letter-spacing: 1.5px;text-align: justify;padding: 10px;color: rgb(68, 68, 68);line-height: 1.75em;box-sizing: border-box;\">\n<p style=\"font-family: Helvetica, Arial, sans-serif;font-size: medium;line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u5728T790M\u8010\u836f\u7684\u60a3\u8005\u4e2d\uff0c\u5965\u5e0c\u66ff\u5c3c\u5bf9\u7167\u4e4b\u524d\u7684\u6807\u51c6\u7597\u6cd5-\u5316\u7597\u4e5f\u5448\u73b0\u51fa\u78be\u538b\u5f0f\u7684\u80dc\u5229\uff0c\u521b\u9020\u4e86\u80bf\u7624\u53f2\u4e0a<strong>\u4e24\u4e2a\u8bb0\u5f55<\/strong>\u3002<\/span><\/p>\n<p style=\"font-family: Helvetica, Arial, sans-serif;font-size: medium;line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u27a4\u4ece\u4e34\u5e8a\u8bd5\u9a8c\u5230\u4e0a\u5e02\u8bb8\u53ef\u4ec5\u5386\u65f6\u4e24\u5e74\u534a\uff0c\u6253\u7834\u4e86\u683c\u5217\u536b\u5c18\u5c01\u5df2\u4e45\u7684\u4e09\u5e74\u8bb0\u5f55\uff01<\/span><\/p>\n<p style=\"font-family: Helvetica, Arial, sans-serif;font-size: medium;line-height: 1.75em;\"><span style=\"font-size: 15px;\">\u27a4<span style=\"color: rgb(68, 68, 68);font-family: Helvetica, Arial, sans-serif;font-size: 15px;letter-spacing: 1.5px;text-align: justify;\">\u4ece\u53d7\u7406\u4e0a\u5e02\u6279\u51c6\u4ec5\u4ec5\u7528\u4e867\u4e2a\u6708\uff01\u622a\u6b62\u81f32018\u5e746\u6708\uff0c<\/span>\u6210\u4e3a\u4e86\u4e2d\u56fd\u83b7\u6279\u6700\u5feb\u7684\u65b0\u836f\uff01<\/span><\/p>\n<\/section>\n<section style=\"height: 2px;background-color: rgb(0, 128, 255);border-radius: 10px;color: rgb(255, 255, 255);box-sizing: border-box;\"><\/section>\n<section style=\"height:2px;text-align:right;margin-top:3px;\">\n<section style=\"width: 40px;height: 2px;background-color: rgb(0, 128, 255);border-radius: 10px;opacity: 0.6;display: inline-block;vertical-align: top;color: rgb(255, 255, 255);box-sizing: border-box;\"><\/section>\n<\/section>\n<section style=\"height:2px;text-align:right;margin-top:3px;\">\n<section style=\"width: 20px;height: 2px;background-color: rgb(0, 128, 255);border-radius: 10px;opacity: 0.3;display: inline-block;vertical-align: top;color: rgb(255, 255, 255);box-sizing: border-box;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section  class=\"_135editor\" style=\"border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box;\">\n<p><br  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\"><\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u7edd\u4f73\u7684\u7597\u6548\uff0c\u81ea\u5e26\u5149\u73af\u7684\u63a8\u9500\uff0c\u8ba9\u5965\u5e0c\u66ff\u5c3c\u6210\u4e3a\u4e86EGFR-TKI\u6700\u597d\u7684\u4ee3\u8a00\u8005\uff0c\u5e02\u573a\u4e0a\u4e00\u8def\u9ad8\u6b4c\u731b\u8fdb\uff0c\u672a\u6765\u53ef\u671f\u3002\u4e0d\u8fc7\u5965\u5e0c\u66ff\u5c3c\u6700\u5927\u7684\u7f3a\u9677\u5c31\u662f\u5b83\u7684\u4ef7\u683c\uff0c\u6bcf\u5e74\u9ad8\u8fbe20\u4e07\u5143\uff0c\u800c\u4e9a\u6d32\u60a3\u8005\u5177\u6709\u4f17\u591a\u7684\u60a3\u8005\u7fa4\u4f53\uff0c\u6ca1\u6709\u7f8e\u56fd\u5f3a\u5927\u7684\u533b\u7597\u4f53\u7cfb\u652f\u6491\uff0c\u5982\u4f55\u6d88\u5316\u8fd9\u4e48\u5927\u7684\u4e00\u4e2a\u5e02\u573a\u4e5f\u662f\u4e00\u4e2a\u96be\u9898\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">&nbsp;<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u4e0d\u8fc7\u53ef\u559c\u7684\u662f\uff0c<\/span><span style=\"font-size: 15px;color: rgb(0, 128, 255);\"><strong>\u76ee\u524d\u4e2d\u56fd\u9996\u4e2a\u539f\u521b\u7684\u7b2c\u4e09\u4ee3EGFR\u9776\u5411\u6291\u5236\u5242\u827e\u7ef4\u66ff\u5c3c\u5df2\u88abCDE\u7eb3\u5165\u7b2c\u4e09\u5341\u4e00\u6279\u4f18\u5148\u5ba1\u8bc4\u7a0b\u5e8f\uff0c\u827e\u7ef4\u66ff\u5c3c\u7684\u4e0a\u5e02\u5c06\u4e3a\u6211\u56fd\u5e7f\u5927\u60a3\u8005\u63d0\u4f9b\u65b0\u7684\u6cbb\u7597\u9009\u62e9\uff0c\u7f13\u89e3\u60a3\u8005\u6c89\u91cd\u7684\u533b\u7597\u8d1f\u62c5\u3002<\/strong><\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><br  \/><\/p>\n<section  label=\"Powered by 135editor.com\" style=\"font-size:16px;font-family:\u5fae\u8f6f\u96c5\u9ed1;\">\n<section  label=\"Powered by 135editor.com\">\n<section class=\"_135editor\"   style=\"border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box;\">\n<section class=\"_135editor\"   style=\"border-width: 0px;border-style: none;border-color: initial;display: inline-block;box-sizing: border-box;\"  >\n<p style=\"margin-top: 8px;padding-right: 10px;font-weight: bold;line-height: 28px;max-width: 100%;color: rgb(0, 128, 255);min-height: 32px;border-bottom: 2px solid rgb(0, 128, 255);border-top-color: rgb(0, 128, 255);border-right-color: rgb(0, 128, 255);border-left-color: rgb(0, 128, 255);text-align: justify;\"><span class=\"autonum\" placeholder=\"1\" style=\"border-radius: 80% 100% 90% 20%;color: rgb(255, 255, 255);display: block;float: left;line-height: 20px;margin-right: 8px;max-width: 100%;padding: 4px 10px;background-color: rgb(0, 128, 255);\"  title=\"\">2<\/span><strong><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\">ALK\u6291\u5236\u5242<\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: justify;line-height: normal;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">&nbsp;<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">EML4-ALK\u57fa\u56e0\u878d\u5408\u662f\u7ee7EGFR\u57fa\u56e0\u7a81\u53d8\u540e\u53c8\u4e00\u5927\u7684\u81f4\u764c\u7a81\u53d8\u3002EML4-ALK\u57fa\u56e0\u878d\u5408\u5728\u767d\u79cd\u548c\u4e2d\u56fdNSCLC\u60a3\u8005\u4e2d\u7684\u8868\u8fbe\u9633\u6027\u7387\u5206\u522b\u4e3a5%\u548c3.3%-6.1%\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">&nbsp;<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"color: rgb(0, 128, 255);\"><strong><span style=\"font-size: 15px;\">\u76ee\u524d\u5df2\u6709\u56db\u6b3e\u836f\u7269\u4e0a\u5e02\uff0c\u4e00\u4ee3ALK\u6291\u5236\u5242\u514b\u5511\u66ff\u5c3c\u3001\u4e8c\u4ee3ALK\u6291\u5236\u52423\u4e2a\u3002<\/span><\/strong><\/span><\/p>\n<p style=\"text-align: justify;line-height: normal;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\"><br  \/><\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/9-1538272962.jpg\" alt=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\" title=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\"  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\"><\/span><\/p>\n<section  label=\"Powered by 135editor.com\" style=\"font-size:16px;font-family:\u5fae\u8f6f\u96c5\u9ed1;\">\n<section  label=\"Powered by 135editor.com\">\n<section class=\"_135editor\"   style=\"border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box;\">\n<section class=\"135brush\" style=\"margin-top: 10px;padding: 15px;color: rgb(123, 123, 111);text-align: justify;background-color: rgb(245, 245, 244);box-sizing: border-box;\">\n<p style=\"font-family: Helvetica, Arial, sans-serif;font-size: medium;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);font-family: \u5fae\u8f6f\u96c5\u9ed1;\">\u514b\u5511\u66ff\u5c3c\u662f\u9996\u4e2a\u53e3\u670d\u7684ALK\u6291\u5236\u5242\uff0c\u540c\u65f6\u4e5f\u662fc-Met\u548cROS1\u6291\u5236\u5242\u3002\u7528\u4e8e\u6cbb\u7597\u901a\u8fc7FDA\u6279\u51c6\u7684\u68c0\u6d4b\u65b9\u6cd5\u8bca\u65ad\u4e3aALK\u9633\u6027\u548cROS1\u9633\u6027\u7684\u8f6c\u79fb\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff0c\u548cEGFR\u6291\u5236\u5242\u7c7b\u4f3c\uff1a<\/span><\/p>\n<p style=\"font-family: Helvetica, Arial, sans-serif;font-size: medium;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);font-family: \u5fae\u8f6f\u96c5\u9ed1;\">\u2460&nbsp;&nbsp;&nbsp;ALK\u6291\u5236\u5242\u76f8\u6bd4\u4e4b\u524d\u7684\u6807\u51c6\u7597\u6cd5\uff0c\u6574\u4f53\u7597\u6548\u66f4\u597d\u3002<\/span><\/p>\n<p style=\"font-family: Helvetica, Arial, sans-serif;font-size: medium;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);font-family: \u5fae\u8f6f\u96c5\u9ed1;\">\u2461\u60a3\u8005\u901a\u5e38\u5728\u4e00\u5e74\u4f7f\u7528\u540e\u4f1a\u51fa\u73b0\u8010\u836f\u7a81\u53d8\uff0c\u5176\u4e2d\u6700\u4e3b\u8981\u7684\u8010\u836f\u673a\u5236\u662fALK\u7684\u7ee7\u53d1\u7a81\u53d8\uff0c\u9700\u8981\u66f4\u65b0\u7684\u9776\u5411\u836f\u7269\u3002<\/span><\/p>\n<p style=\"font-family: Helvetica, Arial, sans-serif;font-size: medium;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);font-family: \u5fae\u8f6f\u96c5\u9ed1;\">\u2462\u4e0d\u5bb9\u6613\u900f\u8fc7\u8840\u8111\u5c4f\u969c\uff0c\u5bf9\u4e8e\u8111\u8f6c\u79fb\u7684\u6548\u679c\u4e0d\u4f73\u3002<\/span><\/p>\n<\/section>\n<section style=\"height: 20px;background-image: url('http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/1-1538272965.png');background-size: 50% 100%;background-repeat: no-repeat;\"><\/section>\n<\/section>\n<section  class=\"_135editor\" style=\"border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box;\">\n<p><br  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\"><\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u7b2c\u4e8c\u4ee3ALK\u6291\u5236\u5242\u6d3b\u6027\u66f4\u597d\uff0c\u540c\u65f6\u5728\u6b63\u5e38\u4eba\u4f53\u7ec4\u7ec7\u91ccALK\u86cb\u767d\u6ca1\u6709EGFR\u86cb\u767d\u8868\u8fbe\u90a3\u4e48\u591a\uff0c\u6240\u4ee5\u4e8c\u4ee3ALK\u6291\u5236\u5242\u5728\u4e34\u5e8a\u4f7f\u7528\u4e2d\u66f4\u52a0\u5e7f\u6cdb\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">&nbsp;<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u5176\u4e2d<\/span><span style=\"font-size: 15px;color: rgb(0, 128, 255);\"><strong>\u7f57\u6c0f\u516c\u53f8\u7684\u827e\u4e50\u66ff\u5c3c<\/strong><\/span><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u6210\u4e3a\u4e86\u5176\u4e2d\u7684\u4f7c\u4f7c\u8005\uff0c\u7528\u4e8e<\/span><strong><span style=\"font-size: 15px;color: rgb(0, 128, 255);\">\u6cbb\u7597ALK\u9633\u6027\u7684\u975e\u5c0f\u7ec6\u80de\u80ba\u764c<\/span><\/strong><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u30022017\u5e74ASCO\u4f1a\u8bae\u4e0a\uff0c\u827e\u4e50\u66ff\u5c3c\u4e0e\u514b\u5511\u66ff\u5c3c\u4e00\u7ebf\u6cbb\u7597\u7684\u5934\u5bf9\u5934\u7684\u6bd4\u8f83\u7814\u7a76\u4e2d\uff0c\u300aNCCN\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u4e34\u5e8a\u5b9e\u8df5\u6307\u5357\u300b\u6b63\u5f0f\u786e\u7acb\u827e\u4e50\u66ff\u5c3c\u4e3aALK\u9633\u6027\u7684NSCLC\u60a3\u8005\u4e00\u7ebf\u6cbb\u7597\u7684\u5730\u4f4d\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">&nbsp;<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u5e02\u573a\u8868\u73b0\u4e0a\u6765\u770b\uff0c\u7f57\u6c0f\u516c\u53f8\u7684\u827e\u4e50\u66ff\u5c3c\u51ed\u501f\u7597\u6548\u4e0a\u7684\u4f18\u52bf\uff0c\u5448\u73b0\u51fa\u98de\u901f\u589e\u957f\u7684\u8d8b\u52bf\uff0c\u6709\u671b\u572818\u5e74\u8d85\u8d8a\u8f89\u745e\uff0c\u6210\u4e3aALK+ NSCLC\u7684\u738b\u8005\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: normal;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\"><br  \/><\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"\"           style=\"width: 558px;height: 287px;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/7-1538272962.jpg\" alt=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\" title=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\"  \/><\/p>\n<p style=\"text-align: center;line-height: normal;\"><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"color: rgb(0, 128, 255);\"><strong><span style=\"font-size: 15px;\">\u8f89\u745e\u516c\u53f8\u63a8\u51fa\u7684\u7b2c\u4e09\u4ee3ALK\u6291\u5236\u5242<\/span><\/strong><\/span><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\uff0c\u4e3b\u8981\u9776\u5411ALK\u548cROS1\uff0c\u53ef\u6291\u5236\u514b\u5511\u66ff\u5c3c\u8010\u836f\u76849\u79cd\u7a81\u53d8\uff0c\u51e0\u4e4e\u53ef\u514b\u670d\u6240\u6709\u8010\u836f\u7a81\u53d8\uff0c\u5177\u6709\u8f83\u5f3a\u7684\u8840\u8111\u5c4f\u969c\u900f\u8fc7\u80fd\u529b\uff0c\u5165\u8111\u6548\u679c\u8f83\u5f3a\uff0c\u7279\u522b\u9002\u5408\u5bf9\u5176\u4ed6ALK\u8010\u836f\u7684\u665a\u671fNSCLC\u60a3\u8005\u3002\u76ee\u524d\u5df2\u7ecf\u8fdb\u5165\u4e86<\/span><strong><span style=\"color: rgb(0, 128, 255);font-size: 24px;\">\u2162<\/span><\/strong><span style=\"font-size: 15px;color: rgb(0, 128, 255);\"><strong>\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u6709\u671b\u63a5\u66ff\u514b\u5511\u66ff\u5c3c\u7684\u8f89\u714c\u3002<\/strong><\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\"><br  \/><\/span><\/p>\n<section  label=\"Powered by 135editor.com\" style=\"font-size:16px;font-family:\u5fae\u8f6f\u96c5\u9ed1;\">\n<section  label=\"Powered by 135editor.com\">\n<section class=\"_135editor\"   style=\"border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box;\">\n<section class=\"_135editor\"   style=\"border-width: 0px;border-style: none;border-color: initial;display: inline-block;box-sizing: border-box;\"  >\n<p style=\"margin-top: 8px;padding-right: 10px;font-weight: bold;line-height: 28px;max-width: 100%;color: rgb(0, 128, 255);min-height: 32px;border-bottom: 2px solid rgb(0, 128, 255);border-top-color: rgb(0, 128, 255);border-right-color: rgb(0, 128, 255);border-left-color: rgb(0, 128, 255);text-align: justify;\"><span class=\"autonum\" placeholder=\"1\" style=\"border-radius: 80% 100% 90% 20%;color: rgb(255, 255, 255);display: block;float: left;line-height: 20px;margin-right: 8px;max-width: 100%;padding: 4px 10px;background-color: rgb(0, 128, 255);\"  title=\"\" >3<\/span><strong style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\">\u6297\u8840\u7ba1\u751f\u6210\u7684\u5355\u6297<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"text-align: justify;line-height: normal;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\"><br  \/><\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u8840\u7ba1\u751f\u6210\u662fNSCLC\u53d1\u751f\u3001\u751f\u957f\u548c\u8f6c\u79fb\u7684\u5fc5\u7ecf\u8fc7\u7a0b\uff0cVEGF\u662f\u8840\u7ba1\u751f\u6210\u7684\u4e3b\u8981\u8c03\u8282\u5206\u5b50\uff0cVEGF\u8868\u8fbe\u589e\u52a0\u5f80\u5f80\u63d0\u793a\u9884\u540e\u4e0d\u4f73\u3002VEGF\u53d7\u4f53\u62ee\u6297\u5242\u51ed\u501f\u5176\u4e34\u5e8a\u4e2d\u826f\u597d\u7684\u7597\u6548\uff0c\u5df2\u7ecf\u65a9\u83b7\u4e86\u591a\u4e2a\u80bf\u7624\u9002\u5e94\u75c7\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">&nbsp;<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"color: rgb(0, 128, 255);\"><strong><span style=\"font-size: 15px;\">\u76ee\u524d\u5df2\u7ecf\u4e0a\u5e02\u4e86\u4e24\u4e2a\u5355\u6297\uff1a\u7f57\u6c0f\u7684\u8d1d\u4f10\u73e0\u5355\u6297(VEGFR\u5355\u6297)\u3001\u8bfa\u534e\u516c\u53f8\u7684\u96f7\u83ab\u82a6\u5355\u6297\u3001(VEGFR2\u5355\u6297)\u3002<\/span><\/strong><\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\"><br  \/><\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u8d1d\u4f10\u73e0\u5355\u6297\u901a\u8fc7\u7ed3\u5408\u4eba\u8840\u7ba1\u5185\u76ae\u751f\u957f\u56e0\u5b50(VEGF)\u4ee5\u963b\u65ad\u5176\u4e0e\u5185\u76ae\u7ec6\u80de\u4e0a\u7684\u53d7\u4f53\u7ed3\u5408\u4ece\u800c\u53d1\u6325\u4f5c\u7528\uff0c\u662f\u5168\u7403\u9996\u4e2a\u53ef\u5e7f\u6cdb\u7528\u4e8e\u591a\u79cd\u80bf\u7624\u7684\u6297\u8840\u7ba1\u751f\u6210\u836f\u7269\u3002\u9664\u4e86\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u8fd9\u4e2a\u9002\u5e94\u75c7\u5916\uff0c\u8fd8\u5305\u62ec\u4e86\u8f6c\u79fb\u6027\u7ed3\u76f4\u80a0\u764c\u3001\u5bab\u9888\u764c\u3001\u5375\u5de2\u764c\u3001\u8f6c\u79fb\u6027\u4e73\u817a\u764c\u548c\u6076\u6027\u80f6\u8d28\u7624\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">&nbsp;<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u4e0d\u8fc7\u8d1d\u4f10\u73e0\u5355\u6297\u4e5f\u5f00\u59cb\u9762\u4e34\u4e13\u5229\u7684\u5371\u673a\uff0c\u6b27\u6d32\u4e13\u52292018\u5e74\u5230\u671f\uff0c\u7f8e\u56fd\u52302019\u5e74\uff0c\u5df2\u7ecf\u53d7\u5230\u4e86\u591a\u5bb6\u516c\u53f8\u7684\u89ca\u89ce\uff0c\u51fa\u73b0\u4e86\u4e0b\u6ed1\u7684\u8ff9\u8c61\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">&nbsp;<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"color: rgb(0, 128, 255);\"><strong><span style=\"font-size: 15px;\">\u96f7\u83ab\u82a6\u5355\u6297\u548c\u8d1d\u4f10\u73e0\u5355\u6297<\/span><\/strong><\/span><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u4f5c\u7528\u65b9\u5f0f\u7c7b\u4f3c\uff0c\u9776\u5411\u4e8e\u8840\u7ba1\u5185\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53(VEGFR2)\uff0c\u53ef\u901a\u8fc7\u6291\u5236\u914d\u4f53\u523a\u6fc0\u7684VEGFR2\u6d3b\u5316\uff0c\u963b\u6b62\u8840\u7ba1\u5185\u76ae\u7ec6\u80de\u7684\u589e\u6b96\u548c\u8fc1\u79fb\u3002\u8be5\u836f\u7528\u4e8e\u6cbb\u7597\u665a\u671f\u80c3\u764c\u6216\u80c3\u98df\u7ba1\u7ed3\u5408\u90e8\u817a\u764c\u3001\u8f6c\u79fb\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u548cEGFR\u6216ALK\u57fa\u56e0\u7a81\u53d8\u80bf\u7624\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">&nbsp;<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u968f\u7740\u9002\u5e94\u75c7\u7684\u4e0d\u65ad\u6269\u5927\uff0c\u540c\u65f6\u6ca1\u6709\u4e13\u5229\u5230\u671f\u7684\u5371\u673a\uff0c\u5e02\u573a\u4efd\u989d\u6709\u671b\u5f97\u5230\u8fdb\u4e00\u6b65\u7684\u6500\u5347\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: normal;\"><br  \/><\/p>\n<p style=\"text-align: center;\"><img class=\"\"           style=\"width: 558px;height: 155px;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/7-1538272963.jpg\" alt=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\" title=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\"  \/><\/p>\n<p style=\"line-height: normal;\"><br  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"color: rgb(0, 128, 255);\"><strong><span style=\"font-size: 15px;\">\u793c\u6765\u7814\u53d1\u7684Necitumumab(EGFR\u5355\u6297)<\/span><\/strong><\/span><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u5e26\u6709\u9ed1\u6846\u8b66\u544a\uff0c\u5b58\u5728\u4e25\u91cd\u7684\u98ce\u9669\uff0c\u9664\u4e86\u4f4e\u9541\u8840\u75c7\u5916\uff0c\u8fd8\u5305\u62ec\u5fc3\u810f\u9aa4\u505c\u548c\u731d\u6b7b\u3002\u52a0\u4e0a\u5e02\u573a\u5df2\u7ecf\u5b58\u5728\u4e09\u4ee3\u5c0f\u5206\u5b50EGFR-TKIs\uff0c\u7ade\u4e89\u5f02\u5e38\u6fc0\u70c8\uff0cNecitumumab\u5e02\u573a\u8868\u73b0\u60e8\u6de1\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\"><br  \/><\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u7531\u4e8e\u7bc7\u5e45\u95ee\u9898\uff0c\u90e8\u5206\u6291\u5236\u5242\u6ca1\u6709\u6458\u9009\uff0c\u8be6\u60c5\u53ef\u53c2\u8003<\/span><span style=\"font-size: 15px;color: rgb(0, 128, 255);\"><strong>\u836f\u6e21\u6570\u636e\u5e93<\/strong><\/span><span style=\"font-size: 15px;color: rgb(0, 0, 0);\">\u3002<\/span><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\"><br  \/><\/span><\/p>\n<p style=\"text-align: center;line-height: normal;\"><strong><span style=\"font-size: 15px;color: rgb(0, 0, 0);background-color: rgb(255, 218, 81);\">\u626b\u63cf\u4e0b\u65b9\u4e8c\u7ef4\u7801<\/span><\/strong><\/p>\n<p style=\"text-align: center;line-height: normal;\"><strong><span style=\"font-size: 15px;color: rgb(0, 0, 0);background-color: rgb(255, 218, 81);\">\u7acb\u5373\u83b7\u53d6\u66f4\u591a\u6570\u636e<\/span><\/strong><\/p>\n<p style=\"text-align: center;line-height: normal;\"><img class=\"\"      style=\"width: 186px;height: 186px;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/8-1538272963.png\" alt=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\" title=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\"  \/><\/p>\n<p style=\"text-align: justify;line-height: 1.75em;\"><span style=\"font-size: 15px;color: rgb(0, 0, 0);\"><\/span><br  \/><\/p>\n<section  label=\"Powered by 135editor.com\" style=\"font-size:16px;font-family:\u5fae\u8f6f\u96c5\u9ed1;\">\n<section  label=\"Powered by 135editor.com\">\n<section class=\"_135editor\"   style=\"border-width: 0px;border-style: none;border-color: initial;box-sizing: border-box;\">\n<section style=\"text-align: center;\"><img class=\"\"      style=\"width: 80%;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/9-1538272963.gif\" alt=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\" title=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\"  \/><\/section>\n<\/section>\n<p style=\"text-align: center;line-height: 1.5em;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzA5MjEzODQ3NA==&amp;mid=2655763118&amp;idx=1&amp;sn=68350d922a4217ed2b750c7eef2ea831&amp;chksm=8bcea42bbcb92d3dcbfb13b1e1e32fbb9e91662cf7aae10e5dbe93e77b85779ef05310a58473&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"text-decoration: underline;font-size: 14px;\"><span style=\"font-size: 14px;\">\u77e5\u9053\u5417\uff1f\u65b0\u7248\u836f\u6e21App\u65b0\u6dfb\u53ef\u89c6\u5316\u529f\u80fd\uff0c\u8ba9\u4f60\u6e05\u6670\u6d1e\u5bdf\u884c\u4e1a\u6570\u636e<\/span><\/a><br  \/><\/p>\n<p style=\"text-align: center;line-height: 1.5em;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzA5MjEzODQ3NA==&amp;mid=2655763117&amp;idx=2&amp;sn=a0d36347addcb143f07a94b2145af365&amp;chksm=8bcea428bcb92d3e87aa896198aa18cc73bde652e52be6dc67ee455d0e6893923e3468e6f0df&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"text-decoration: underline;font-size: 14px;\"><span style=\"font-size: 14px;\">\u53ca\u65f6\u4e86\u89e3\u884c\u4e1a\u878d\u8d44\u52a8\u5411\uff0c\u505a\u806a\u660e\u7684\u51b3\u7b56\u8005<\/span><\/a><br  \/><\/p>\n<p style=\"text-align: center;line-height: 1.5em;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzA5MjEzODQ3NA==&amp;mid=2655763099&amp;idx=1&amp;sn=77276dc32d882674706bac13ad8c277d&amp;chksm=8bcea41ebcb92d082b71581b38ab76cd671103230524b8337c3b7d4b5332d8bb6f90fd098729&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"text-decoration: underline;font-size: 14px;\"><span style=\"font-size: 14px;\">142\u4e2a\u5316\u836f\u64a4\u5e02\uff0c49\u4e2a\u6e90\u4e8e\u201c\u5b89\u5168\u6027\u201d\uff01<\/span><\/a><br  \/><\/p>\n<p style=\"text-align: center;line-height: 1.5em;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzA5MjEzODQ3NA==&amp;mid=2655762860&amp;idx=1&amp;sn=3d820e84c9f5e233b916a8f514f47934&amp;chksm=8bcea729bcb92e3f996d56233a0ecd93880de5c7d3182f113213f70d58959c0ed06ce5e8c30f&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"text-decoration: underline;font-size: 14px;\"><span style=\"font-size: 14px;\">\u5168\u7403\u7545\u9500\u836fTOP10\u7684\u9ed1\u6846\u8b66\u544a\u7b80\u8ff0<\/span><\/a><\/p>\n<p style=\"text-align: center;line-height: 1.5em;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzA5MTAzODE3MQ==&amp;mid=2651936048&amp;idx=6&amp;sn=1a3a0b2f16f330f4ca6b1452292fa17c&amp;chksm=8be77d84bc90f492f910f741271be2c77b998038ca02b553798e42ac8e81356ab08a0051c89e&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"text-decoration: underline;font-size: 14px;\"><span style=\"font-size: 14px;\">\u5168\u90e8\u514d\u8d39\uff01\u8fd1\u671f\u836f\u6e21\u5b66\u9662\u76f4\u64ad\u8bfe\u6c47\u603b<\/span><\/a><br  \/><\/p>\n<p style=\"text-align: center;line-height: 1.5em;\"><br  \/><\/p>\n<\/section>\n<\/section>\n<p><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzA5MjEzODQ3NA==&amp;mid=2655762488&amp;idx=2&amp;sn=8f278096debef35b578d6e03e56e3488&amp;chksm=8bcea6bdbcb92fabd503d5bb73cc273697ebf0769fbb7bfb96056b5dce3644647bd18e9d2fbe&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"text-align: center;white-space: normal;\"><span class=\"js_jump_icon h5_image_link\"  style=\"top: auto;left: auto;right: auto;bottom: auto;\"><img class=\"\"               style=\"width: 100%;height: auto;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/1-1538272964.jpg\" alt=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\" title=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\"  \/><\/span><\/a><\/p>\n<p style=\"text-align: center;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzA5MjEzODQ3NA==&amp;mid=2655756292&amp;idx=6&amp;sn=8ae873807e0f13e4eaaea32a11123559&amp;chksm=8bcebe81bcb9379718fa3f7c97699a16524969f4b74d9a3e1b46329a304786628bc806562b51&amp;scene=21#wechat_redirect\" target=\"_blank\"><span class=\"js_jump_icon h5_image_link\"  style=\"top: auto;left: auto;margin: 0px;right: auto;bottom: auto;\"><img class=\"\"               style=\"margin: 0px;width: 100%;height: auto;top: auto;left: auto;right: auto;bottom: auto;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/10-1538272964.jpeg\" alt=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\" title=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\"  \/><\/span><\/a><\/p>\n<p style=\"text-align: center;\"><img class=\"\"           style=\"width: 100%;height: auto;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/1-1538272964.jpeg\" alt=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\" title=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\"  \/><\/p>\n<p style=\"text-align: center;\"><img class=\"\"           style=\"width: 100%;height: auto;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/2-1538272965.jpeg\" alt=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\" title=\"2018\u5e74\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e02\u573a\u5206\u6790\u548c\u8d8b\u52bf\u8d70\u5411\u2014\u2014\u9776\u5411\u836f\u7269\u7bc7\"  \/><\/p>\n<section class=\"RankEditor\" style=\"margin-top: 20px;\">\n<section style=\"display: inline-block;vertical-align: middle;width:12%;box-sizing: border-box;\">\n<section style=\"margin-top: 0.5em;margin-bottom: 0.5em;box-sizing: border-box;\"><\/section>\n<\/section>\n<section style=\"display:inline-block;width: 88%;padding:5px;box-sizing: border-box;vertical-align:middle;\">\n<p class=\"active brush\" style=\"box-sizing: border-box;font-size: 16px;color: rgb(121,121,121);min-width:1px;\"><span style=\"font-size: 15px;\">\u7acb\u5373\u89e3\u9501\u4f60\u7684\u638c\u4e0a\u4e13\u4e1a\u5de5\u5177\uff01<\/span><\/p>\n<\/section>\n<\/section><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u4f5c\u4e3a\u53d1\u75c5\u7387\u548c\u6b7b\u4ea1\u6570\u76ee\u6700\u591a\u7684\u6076\u6027\u80bf\u7624\u4e4b\u4e00\u2014\u2014\u80ba\u764c\uff0c\u6210\u4e3a\u65e0\u6570\u60a3\u8005\u7684\u68a6\u9b47\uff0c\u533b\u836f\u7814\u53d1\u7684\u7126\u70b9\uff0c\u5e02\u573a\u4e0a\u7684\u5fc5\u4e89\u4e4b\u5730\u3002 \u8fd9\u4e2a\u75be [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":55207,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/55206"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=55206"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/55206\/revisions"}],"predecessor-version":[{"id":55223,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/55206\/revisions\/55223"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/55207"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=55206"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=55206"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=55206"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}