{"id":55299,"date":"2018-09-28T01:00:00","date_gmt":"2018-09-30T02:03:28","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/30\/%e8%af%ba%e5%8d%8ecat-t%e4%b8%ad%e5%9b%bd%e5%88%b6%e9%80%a0-%e4%b8%ba%e4%bd%95%e9%80%89%e6%8b%a9ta\/"},"modified":"2018-09-30T10:03:29","modified_gmt":"2018-09-30T02:03:29","slug":"%e8%af%ba%e5%8d%8ecat-t%e4%b8%ad%e5%9b%bd%e5%88%b6%e9%80%a0-%e4%b8%ba%e4%bd%95%e9%80%89%e6%8b%a9ta","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/55299\/","title":{"rendered":"\u8bfa\u534eCAT-T\u4e2d\u56fd\u5236\u9020 \u4e3a\u4f55\u9009\u62e9TA"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p><span style=\"font-size: 14px;\">\u745e\u58eb\u836f\u4f01\u8bfa\u534e\u548c\u897f\u6bd4\u66fc\u7b7e\u8ba2\u534f\u8bae\uff0c\u59d4\u6258\u8fd9\u5bb6\u7f8e\u56fd\u4e0a\u5e02\u7684\u516c\u53f8\u5728\u4e2d\u56fd\u751f\u4ea7\u548c\u4f9b\u5e94\u6cbb\u7597\u8840\u6db2\u7624\u7684\u7ec6\u80de\u7597\u6cd5\uff0cCAR-T\u7684Kymriah\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p><span style=\"font-size: 14px;\">\u8bfa\u534e\u4e3a\u4f55\u9009\u62e9\u4e86\u897f\u6bd4\u66fc\uff08CMBG\uff09\uff1f<\/span><\/p>\n<p><br  \/><\/p>\n<p><span style=\"font-size: 14px;\">\u897f\u6bd4\u66fc\u5168\u79f0\u662fCellular BioMedicine Group (CBMG), \u6210\u7acb\u4e8e2001\u5e74\uff0c\u76ee\u524d\u5728\u7ebd\u7ea6\u4ea4\u6613\u6240\u4e0a\u5e02\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p><span style=\"font-size: 14px;\">\u6839\u636e\u7ebd\u4ea4\u6240\u663e\u793a\uff0c\u516c\u53f8\u603b\u90e8\u8bbe\u5728\u52a0\u5dde\u7684\u5e93\u73c0\u63d0\u8bfa\u5e02\uff0c\u8fd9\u4e5f\u662f\u82f9\u679c\u516c\u53f8\u7684\u6240\u5728\u5730\u3002<\/span><\/p>\n<p style=\"text-align: left;text-indent: 2em;\"><img class=\"\"       style=\"width: 352px;height: 208px;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/6-1538273009.jpeg\" alt=\"\u8bfa\u534eCAT-T\u4e2d\u56fd\u5236\u9020 \u4e3a\u4f55\u9009\u62e9TA\" title=\"\u8bfa\u534eCAT-T\u4e2d\u56fd\u5236\u9020 \u4e3a\u4f55\u9009\u62e9TA\"><\/p>\n<p><span style=\"font-size: 14px;\">CMBG\u8fd1\u5e74\u6765\u4e00\u76f4\u6ce8\u91cd\u5f00\u53d1\u80bf\u7624\u514d\u75ab\u7684\u9000\u884c\u6027\u75be\u75c5\u7684\u65b0\u7597\u6cd5\uff0c\u91cd\u70b9\u662f\u5f00\u53d1\u548c\u9500\u552e\u6cbb\u7597\u5404\u79cd\u75be\u75c5, \u5982\u764c\u75c7, \u9aa8\u79d1\u548c\u4ee3\u8c22\u75be\u75c5\u7684\u7ec6\u80de\u7597\u6cd5\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p><span style=\"font-size: 14px;\">\u4e3a\u4e86\u8fce\u63a5\u7ec6\u80de\u7597\u6cd5\u7684\u5927\u53d1\u5c55\uff0c\u897f\u6bd4\u66fc\u4e0d\u65ad\u79ef\u6781\u5e03\u5c40\u3002\u6700\u5927\u7684\u4e00\u9879\u4e3e\u52a8\uff0c\u5c31\u662f\u4e0e <span style=\"font-size: 14px;color: rgb(64, 118, 0);\">GE \u533b\u7597\u751f\u547d\u79d1\u5b66\u8fdb\u884c\u4e86\u6218\u7565\u7814\u7a76\u5408\u4f5c<\/span>, \u5171\u540c\u5f00\u53d1\u5d4c\u5408\u4f53\u6297\u539f\u53d7\u4f53 T (CAR-T)\u7ec6\u80de\u548c\u5e72\u7ec6\u80de\u5236\u9020\u7684\u5de5\u4e1a\u63a7\u5236\u8fc7\u7a0b\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p><span style=\"font-size: 14px;\">\u79ef\u6781\u5728\u7ec6\u80de\u751f\u4ea7\u4e0a\u5e03\u5c40\uff0c\u8fd9\u662f\u5438\u5f15\u4e86\u8bfa\u534e\u7684\u4e00\u4e2a\u91cd\u8981\u539f\u56e0\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p><span style=\"font-size: 14px;\">\u8fd9\u5bb6\u745e\u58eb\u836f\u4f01\uff0c\u624b\u4e2d\u63e1\u6709\u7b2c\u4e00\u4e2a\u83b7\u6279\u7684 CAR-T\u7ec6\u80de\u7597\u6cd5\uff0cKymriah\u7ee7\u53bb\u5e745\u6708\u83b7\u5f97\u4e86\u7f8e\u56fdFDA\u7684\u6279\u51c6\u4e4b\u540e\uff0c\u6cbb\u7597B\u7ec6\u80de\u6dcb\u5df4\u7624\u540e\uff0c\u53c8\u5148\u540e\u83b7\u5f97\u4e86\u6b27\u76df\u548c\u52a0\u62ff\u5927\u7684\u9500\u552e\u6388\u6743\u548c\u4e0a\u5e02\u8bb8\u53ef\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p><span style=\"font-size: 14px;\">\u4f46\u662f\uff0c\u4e3a\u4e86\u52a0\u901fCAT-T\u5728\u5168\u7403\u7b2c\u4e8c\u5927\u533b\u836f\u5e02\u573a\uff0c\u4e2d\u56fd\u7684\u5c3d\u5feb\u83b7\u6279\u4e0a\u5e02\uff0c\u8bfa\u534e\u5fc5\u987b\u5bfb\u627e\u5408\u9002\u7684\u751f\u4ea7\u5408\u4f5c\u4f19\u4f34\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p><span style=\"font-size: 14px;\"><span style=\"font-size: 14px;color: rgb(64, 118, 0);\">\u7ec6\u80de\u7597\u6cd5\u5bf9\u4e8e\u751f\u4ea7\u7684\u8981\u6c42\u975e\u5e38\u4e4b\u9ad8<\/span>\uff0c\u662f\u56e0\u4e3a\u4f5c\u4e3a\u4e00\u79cd\u4e2a\u6027\u5316\u7597\u6cd5\uff0cKymriah\u9700\u8981<\/span><\/p>\n<p><span style=\"font-size: 14px;\">\u5728\u7ec6\u80de\u751f\u4ea7\u4e0a\uff0c\u786e\u4fdd\u5728\u76f8\u5bf9\u8f83\u77ed\u7684\u65f6\u95f4\u5185\uff0c<span style=\"font-size: 14px;color: rgb(64, 118, 0);\">\u57fa\u56e0\u7f16\u7801\u4e00\u4e2a\u60a3\u8005\u7684\u514d\u75ab T \u7ec6\u80de\u72e9\uff0c\u6765\u9776\u5411\u548c\u6740\u6b7b\u764c\u7ec6\u80de<\/span>\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p><span style=\"font-size: 14px;\">\u8fd9\u4e00\u8fc7\u7a0b\u8981\u6c42\u4ece\u75c5\u4eba\u8eab\u4e0a\u53d6\u51fa\u8840\u6db2, \u51b7\u51bb\u4fdd\u5b58, \u8fd0\u5230\u5236\u9020\u5de5\u5382, \u91cd\u65b0\u7f16\u7a0b\u5e76\u5728\u5b9e\u9a8c\u5ba4\u5236\u9020, \u7136\u540e\u8fd0\u56de\u7ed9\u75c5\u4eba\u8f93\u6db2, \u6240\u6709\u8fd9\u4e9b\u90fd\u5728\u6700\u77ed\u7684\u65f6\u95f4\u5185\u8bd5\u56fe\u653b\u51fb\u590d\u53d1\u6027\u80bf\u7624\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p><span style=\"font-size: 14px;\">\u76ee\u524d\uff0c\u8bfa\u534e\u5728\u81ea\u5df1\u7684\u65b0\u6cfd\u897f\u5dde\u83ab\u91cc\u65af\u5e73\u539f\u7684\u5de5\u5382\u5185\u751f\u4ea7\u8fd9\u79cd\u7ec6\u80de\u7597\u6cd5\u3002<\/span><\/p>\n<p><span style=\"font-size: 14px;\">\u4e3a\u4e86\u8fdb\u5165\u4e2d\u56fd\u5e02\u573a\uff0c\u5c31\u5fc5\u987b\u6709\u4e00\u4e2a\u9760\u8c31\u7684\u751f\u4ea7\u4f19\u4f34\uff0c\u4e3a\u6b64\uff0c\u8bfa\u534e\u5e0c\u671b\u897f\u6bd4\u66fc\u53ef\u4ee5\u627f\u62c5\u91cd\u8d1f\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p><span style=\"font-size: 14px;\">\u4e3a\u6b64\uff0c\u8bfa\u534e\u5fc3\u7518\u60c5\u613f\uff0c\u4e0d\u4ec5\u5728\u751f\u4ea7\u4e0a\u5408\u4f5c\uff0c\u800c\u4e14\u6295\u51654000\u4e07\u7f8e\u5143\u91cd\u91d1\uff0c\u4e00\u5e45\u540c\u7518\u5171\u82e6\u540c\u821f\u5171\u6d4e\u7684\u59ff\u6001\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p><span style=\"font-size: 14px;\">\u6839\u636e\u8fd9\u4e2a\u5408\u4f5c\u534f\u8bae\uff0c\u8bfa\u534e\u4ee54000\u4e07\u7f8e\u5143\u6536\u8d2dCBMG\u7684145\u4e078257\u80a1\u80a1\u7968\uff0c\u6bcf\u80a1\u7684\u4ef7\u683c\u4e3a<span style=\"font-size: 14px;color: rgb(64, 118, 0);\">27.43\u7f8e\u5143<\/span>\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p><span style=\"font-size: 14px;\">CBMG\u8fd8\u5c06\u6388\u6743\u8bfa\u534e\u5728\u5168\u7403\u8303\u56f4\u5185\u4f7f\u7528\u5176\u7279\u5b9a\u4e13\u7528\u6280\u672f\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p><span style=\"font-size: 14px;\">CBMG\u7684\u4e13\u6709\u7ec6\u80de\u6280\u672f\u5f00\u53d1\u6cbb\u7597\u65b9\u6cd5, \u6839\u636e\u516c\u53f8\u7684\u7f51\u7ad9\uff0c \u8fd9\u4e9b\u5305\u62ec\uff1a<\/span><\/p>\n<ul class=\"list-paddingleft-2\" style=\"list-style-type: disc;\">\n<li>\n<p><span style=\"font-size: 14px;\">\u80bf\u7624\u514d\u75ab\u7ec6\u80de\u7597\u6cd5\u6cbb\u7597\u4e00\u7cfb\u5217\u764c\u75c7;<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-size: 14px;\">\u4eba\u8102\u80aa\u6e90\u6027\u95f4\u5145\u8d28\u7956\u7ec6\u80de\u6cbb\u7597\u5173\u8282\u548c\u81ea\u8eab\u514d\u75ab\u75be\u75c5\uff1b<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-size: 14px;\">\u80bf\u7624\u7ec6\u80de\u7279\u5f02\u6811\u7a81\u72b6\u7ec6\u80de\u6cbb\u7597\uff1b<\/span><\/p>\n<\/li>\n<li>\n<p><span style=\"font-size: 14px;\">Re-Join\u548cAllo-Join\u7597\u6cd5\u6cbb\u7597\u819d\u5173\u8282\u9aa8\u6027\u5173\u8282\u708e\u3002<\/span><\/p>\n<\/li>\n<\/ul>\n<p><br  \/><\/p>\n<p><span style=\"font-size: 14px;\">\u6b64\u5916\uff0cCBMG\u8fd8\u4ece\u4e8b\u5b9e\u9a8c\u5ba4\u5957\u4ef6\u7684\u7814\u7a76\u548c\u751f\u4ea7\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p><span style=\"font-size: 14px;\">\u5728\u56fd\u5185\uff0c\u897f\u6bd4\u66fc\u5c06\u8d1f\u8d23\u5236\u9020Kymriah\uff0c\u800c\u8bfa\u534e\u5219\u8d1f\u8d23\u8425\u9500\u8bb8\u53ef\u7684\u72ec\u5bb6\u529d\u4f60\uff0c\u5e76\u8d1f\u8d23\u4e2d\u56fd\u7684\u5206\u9500\uff0c\u4ea7\u54c1\u6ce8\u518c\u548c\u5546\u4e1a\u5316\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p><span style=\"font-size: 14px;\">\u201c\u6211\u4eec\u5e0c\u671b\u548c\u8bfa\u534e\u4e00\u8d77\uff0c\u4e3a\u4e2d\u56fd\u60a3\u8005\u5e26\u6765\u9996\u4f8bCAR-T\u7ec6\u80de\u7597\u6cd5\u3002\u6b64\u5916\uff0c\u6211\u4eec\u4e5f\u7ee7\u7eed\u4e13\u6ce8\u5f00\u53d1CBMG\u7684\u4e00\u7cfb\u5217\u7f8e\u5143\u80bf\u7624\u8d44\u4ea7\u3002\u201d\u897f\u6bd4\u66fc\u516c\u53f8\u603b\u88c1\u5218\u5fc5\u4f50\uff08Tony Liu\uff09\u5728\u58f0\u660e\u4e2d\u8868\u793a\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p><span style=\"font-size: 14px;\">CBMG\u7684\u80a1\u7968\u5e94\u58f0\u4e0b\u8dcc\uff0c\u8dcc\u5e45\u8d856%\u3002<\/span><\/p>\n<p><img class=\"\"     src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/09\/2-1538273009.jpg\" alt=\"\u8bfa\u534eCAT-T\u4e2d\u56fd\u5236\u9020 \u4e3a\u4f55\u9009\u62e9TA\" title=\"\u8bfa\u534eCAT-T\u4e2d\u56fd\u5236\u9020 \u4e3a\u4f55\u9009\u62e9TA\"><\/p>\n<p><br  \/><\/p>\n<p><span style=\"color: rgb(64, 118, 0);font-size: 14px;\"><em>\u4f60\u5bf9CAR-T\u4e2d\u56fd\u5236\u9020\u600e\u4e48\u770b\uff1f<\/em><\/span><\/p>\n<p><span style=\"color: rgb(64, 118, 0);font-size: 14px;\"><em>\u8bf7\u7559\u8a00\u5206\u4eab\u770b\u6cd5\u3002<\/em><\/span><\/p>\n<p><br  \/><\/p>\n<p><span style=\"font-size: 14px;\"><strong>\u4f60\u53ef\u80fd\u559c\u6b22<\/strong>\uff1a<\/span><\/p>\n<p><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAxOTQwNjM3Ng==&amp;mid=2247487254&amp;idx=1&amp;sn=e853bc53ce013f4349a8345180efff53&amp;chksm=9bc6c451acb14d47e021ac1835e417e67c092c9cc2984fb98cb507a757aa201d998a7591c295&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"font-size: 14px;text-decoration: underline;\"><span style=\"font-size: 14px;\">\u6cbb\u513f\u7ae5\u8840\u764c Yes \u6210\u4ebaNO\uff1a\u82f1\u56fdNICE\u9ad8\u8c03\u62d2CAR-T<\/span><\/a><br  \/><\/p>\n<p><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAxOTQwNjM3Ng==&amp;mid=2247486782&amp;idx=1&amp;sn=02aa22efc8462b32e0b743569eaff9a8&amp;chksm=9bc6c679acb14f6f80738af61d72e54414433a12ba28a30ce4f5d740b8d5a57235abf7d068cd&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"font-size: 14px;text-decoration: underline;\"><span style=\"font-size: 14px;\">PK\u8bfa\u534e \u7b2c\u4e00\u4e2a\u62ff\u6765\u5c31\u7528CAR-T\u6cbb\u7597\u8840\u764c\u8981\u8fdb\u4e34\u5e8a<\/span><\/a><br  \/><\/p>\n<p><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAxOTQwNjM3Ng==&amp;mid=2247486730&amp;idx=1&amp;sn=5319df3d9ab902409664a0fa6aa5213f&amp;chksm=9bc6c64dacb14f5bd9aa43fb7f86721a56bd93409ae622698b64d15d90a40935f3f43d258073&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"font-size: 14px;text-decoration: underline;\"><span style=\"font-size: 14px;\">\u7ade\u4e89\u6fc0\u70c8 \u8bfa\u534e\u82cf\u91d1\u5355\u6297\u9500\u552e\u4e0d\u632f CAR-T\u9996\u6cbb30\u4eba\uff1f<\/span><\/a><br  \/><\/p>\n<p><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzAxOTQwNjM3Ng==&amp;mid=2247486694&amp;idx=1&amp;sn=342c499a61816e633b95fe2109e314d5&amp;chksm=9bc6c7a1acb14eb72198c6c4b650b2233f75651bbc8bfdff142db3fddf660ddb46d8a707d09c&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"font-size: 14px;text-decoration: underline;\"><span style=\"font-size: 14px;\">\u5f81\u670d\u8840\u6db2\u80bf\u7624\uff0c\u534e\u4eba\u5973\u533b\u751f\u5317\u5927\u8bb2\u8ff0CAR-T\u68a6<\/span><\/a><br  \/><\/p>\n<p><br  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51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><em style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(64, 118, 0);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u6bcf\u5929\u7528\u65b0\u8bf4\u8bdd&nbsp;\u51b3\u7b56\u4e0d\u53ef\u6216\u7f3a<\/span><\/em><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica 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