{"id":55775,"date":"2018-09-28T01:00:00","date_gmt":"2018-09-30T02:08:41","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/30\/science%e5%ad%90%e5%88%8a%ef%bc%9a%e5%a6%82%e4%bd%95%e5%a2%9e%e5%8a%a0%e7%99%8c%e7%97%87%e6%82%a3%e8%80%85%e6%9c%89%e7%9b%8a%e8%8f%8c%e7%be%a4%ef%bc%9f\/"},"modified":"2018-09-30T10:08:42","modified_gmt":"2018-09-30T02:08:42","slug":"science%e5%ad%90%e5%88%8a%ef%bc%9a%e5%a6%82%e4%bd%95%e5%a2%9e%e5%8a%a0%e7%99%8c%e7%97%87%e6%82%a3%e8%80%85%e6%9c%89%e7%9b%8a%e8%8f%8c%e7%be%a4%ef%bc%9f","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/55775\/","title":{"rendered":"Science\u5b50\u520a\uff1a\u5982\u4f55\u589e\u52a0\u764c\u75c7\u60a3\u8005\u6709\u76ca\u83cc\u7fa4\uff1f"},"content":{"rendered":"
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\u611f\u67d3\u662f\u5f02\u57fa\u56e0\u9020\u8840\u5e72\u7ec6\u80de\u79fb\u690d\u8fc7\u7a0b\u4e2d\u6700\u5e38\u89c1\u548c\u4e25\u91cd\u7684\u5e76\u53d1\u75c7\u4e4b\u4e00\uff0c\u764c\u75c7\u60a3\u8005\u901a\u5e38\u9700\u8981\u670d\u7528\u5927\u91cf\u7684\u6297\u751f\u7d20\uff0c\u800c\u6297\u751f\u7d20\u6cbb\u7597\u4f1a\u7834\u574f\u60a3\u8005\u80a0\u9053\u5fae\u751f\u7269\u7fa4\u7684\u591a\u6837\u6027\uff0c\u5bfc\u81f4\u8bb8\u591a\u6709\u76ca\u5fae\u751f\u7269\u7684\u4e27\u5931\u3002\u8fd1\u65e5\uff0c\u7eaa\u5ff5\u65af\u9686\u51ef\u7279\u7433\u764c\u75c7\u4e2d\u5fc3\u7684\u7814\u7a76\u4eba\u5458\u627e\u5230\u4e00\u79cd\u5b89\u5168\u6709\u6548\u7684\u65b9\u6cd5\u2014\u2014\u81ea\u4f53\u7caa\u4fbf\u5fae\u751f\u7269\u7fa4\u79fb\u690d(auto-FMT)\uff0c\u53ef\u4ee5\u5e2e\u52a9\u8be5\u624b\u672f\u60a3\u8005\u8865\u5145\u6709\u76ca\u7684\u80a0\u9053\u7ec6\u83cc\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\"Science\u5b50\u520a\uff1a\u5982\u4f55\u589e\u52a0\u764c\u75c7\u60a3\u8005\u6709\u76ca\u83cc\u7fa4\uff1f\"
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\u56fe\u7247\u6765\u6e90\uff1aJonathan Bailey, NHGRI <\/span><\/p>\n


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\u5728\u6700\u65b0\u7684\u7814\u7a76\u4e2d\uff0c\u7814\u7a76\u4eba\u5458\u5c06\u63a5\u53d7\u5f02\u57fa\u56e0\u9020\u8840\u5e72\u7ec6\u80de\u79fb\u690d\u624b\u672f\u7684\u60a3\u8005\u968f\u673a\u5206\u4e3a\u4e24\u7ec4\uff1a\u4e00\u7ec4\u63a5\u53d7\u6807\u51c6\u6cbb\u7597\uff0c\u53e6\u4e00\u7ec4\u63a5\u53d7\uff08auto-FMT\uff09\u6cbb\u7597\u3002\u7ed3\u679c\u53d1\u73b0\uff0c auto-FMT\u7ec4\u80fd\u4f7f\u60a3\u8005\u7684\u6709\u76ca\u80a0\u9053\u7ec6\u83cc\u5728\u6570\u5929\u5185\u6062\u590d\u5230\u63a5\u8fd1\u57fa\u7ebf\u6c34\u5e73\uff0c\u4ece\u800c\u6062\u590d\u5176\u6d88\u5316\u3001\u514d\u75ab\u548c\u5176\u4ed6\u57fa\u672c\u529f\u80fd\u3002\u800c\u6807\u51c6\u6cbb\u7597\u7ec4\uff0c\u60a3\u8005\u6709\u76ca\u83cc\u901a\u5e38\u9700\u8981\u6570\u5468\u65f6\u95f4\u624d\u80fd\u4ece\u6297\u751f\u7d20\u6cbb\u7597\u4e2d\u6062\u590d\uff0c\u4e14\u4f1a\u9762\u4e34\u5176\u4ed6\u4f20\u67d3\u75c5\uff08\u8270\u96be\u68ad\u72b6\u82bd\u80de\u6746\u83cc\uff0cClostridium difficile\uff09\u7684\u98ce\u9669\u3002<\/span><\/p>\n


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\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662\u4e0b\u5c5e\u7684\u56fd\u5bb6\u8fc7\u654f\u548c\u4f20\u67d3\u75c5\u7814\u7a76\u6240\uff08National Institute of Allergy and Infectious Diseases\uff0cNIAID\uff09\u4e3a\u90e8\u5206\u9879\u76ee\u63d0\u4f9b\u4e86\u8d44\u91d1\u3002 
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\"Science\u5b50\u520a\uff1a\u5982\u4f55\u589e\u52a0\u764c\u75c7\u60a3\u8005\u6709\u76ca\u83cc\u7fa4\uff1f\"
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DOI: 10.1126\/scitranslmed.aap9489<\/span><\/p>\n


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NIAID\u4e3b\u4efbAnthony S. Fauci\u535a\u58eb\u8bf4:\u201c\u8fd9\u9879\u91cd\u8981\u7684\u7814\u7a76\u8868\u660e\uff0c\u4f7f\u7528\uff08auto-FMT\uff09\u7684\u4e34\u5e8a\u5e72\u9884\u53ef\u4ee5\u5b89\u5168\u5730\u9006\u8f6c\u5e7f\u8c31\u6297\u751f\u7d20\u6cbb\u7597\u7684\u7834\u574f\u6027\u5f71\u54cd\u3002\u5982\u679c\u8be5\u7ed3\u679c\u5728\u66f4\u5927\u8303\u56f4\u7684\u7814\u7a76\u4e2d\u5f97\u5230\u8bc1\u5b9e\uff0c\u5c31\u53ef\u4ee5\u5728\u5f3a\u5316\u6297\u83cc\u6cbb\u7597\u540e\u8fc5\u901f\u6062\u590d\u4eba\u4f53\u5065\u5eb7\u7684\u5fae\u751f\u7269\u7fa4\u3002\u201d<\/span><\/p>\n


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\u540c\u79cd\u5f02\u4f53\u9020\u8840\u7ec6\u80de\u79fb\u690d\u9700\u8981\u6350\u8d60\u8005\uff08\u901a\u5e38\u662f\u5bb6\u65cf\u6210\u5458\uff09\u63d0\u4f9b\u7ed9\u53d7\u4f53\u5e72\u7ec6\u80de\uff0c\u8fd9\u4e9b\u5e72\u7ec6\u80de\u53ef\u4ee5\u91cd\u5efa\u9aa8\u9ad3\u9020\u8840\u7ec6\u80de\u548c\u514d\u75ab\u529f\u80fd\uff0c\u4ee5\u4fbf\u5bf9\u6297\u764c\u75c7\u3002\u867d\u7136\u6297\u751f\u7d20\u5bf9\u4e8e\u9884\u9632\u5e72\u7ec6\u80de\u53d7\u8005\u7684\u7ec6\u83cc\u611f\u67d3\u81f3\u5173\u91cd\u8981\uff0c\u4f46\u662f\uff0c\u6297\u751f\u7d20\u4e5f\u4f1a\u7834\u574f\u6709\u76ca\u7684\u7ec6\u83cc\uff1b\u8fd9\u4e9b\u7ec6\u83cc\u53ef\u4ee5\u589e\u5f3a\u514d\u75ab\u529f\u80fd\u548c\u62b5\u6297\u611f\u67d3\u3002\u6709\u76ca\u83cc\u7684\u4e27\u5931\u589e\u52a0\u4e86\u67d0\u4e9b\u5371\u53ca\u751f\u547d\u7684\u4f20\u67d3\u75c5\u548c\u79fb\u690d\u7269\u6297\u5bbf\u4e3b\u75c5(GVHD)\u7684\u98ce\u9669\u3002<\/span><\/p>\n


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\u8fd9\u9879\u7814\u7a76\u7684\u5bf9\u8c61\u662f\u764c\u75c7\u60a3\u8005\uff0c\u4ed6\u4eec\u63d0\u4f9b\u81ea\u5df1\u7684\u7caa\u4fbf\u6837\u672c\uff0c\u8fd9\u4e9b\u6837\u672c\u5728\u7ec6\u80de\u79fb\u690d\u524d\u88ab\u51b7\u51bb\u548c\u50a8\u5b58\u3002\u51e0\u5468\u540e\uff0c\u5f53\u533b\u751f\u8bc1\u5b9e\u79fb\u690d\u7684\u7ec6\u80de\u6b63\u5728\u751f\u957f\u65f6\uff0c\u4ed6\u4eec\u8bc4\u4f30\u4e86\u75c5\u4eba\u6709\u76ca\u7684\u80a0\u9053\u7ec6\u83cc\u7684\u72b6\u51b5\u3002\u524d25\u540d\u7f3a\u4e4f\u5df2\u77e5\u6709\u76ca\u83cc\u7684\u60a3\u8005\u88ab\u7eb3\u5165\u4e86\u7814\u7a76\uff0c\u5e76\u88ab\u968f\u673a\u5206\u914d\u5230\u4e0d\u540c\u7684\u6cbb\u7597\u7ec4\uff1a14\u540d\u63a5\u53d7\u704c\u80a0\uff08auto-FMT\uff09\u6cbb\u7597\uff0c11\u540d\u63a5\u53d7\u6807\u51c6\u6cbb\u7597\u3002<\/span><\/p>\n


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\u7ed3\u679c\u663e\u793a\uff0c\u63a5\u53d7\uff08auto-FMT\uff09\u6cbb\u7597\u7684\u60a3\u8005\uff0c\u5176\u7ec6\u83cc\u591a\u6837\u6027\u3001\u6210\u5206\u548c\u529f\u80fd\u5747\u6301\u7eed\u6062\u590d\uff1b11\u4f8b\u5bf9\u7167\u7ec4\u6709\u76ca\u83cc\u7684\u6062\u590d\u5ef6\u8fdf\u3002<\/span><\/p>\n


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\u7814\u7a76\u4eba\u5458\u5c06\u7ee7\u7eed\u76d1\u6d4b\u7814\u7a76\u60a3\u8005\uff0c\u4ee5\u786e\u5b9aauto-FMT\u662f\u5426\u6539\u5584\u60a3\u8005\u9884\u540e\uff0c\u5982\u7ec6\u83cc\u3001\u75c5\u6bd2\u548c\u771f\u83cc\u611f\u67d3\u7684\u53d1\u751f\u7387\u548c\u4e25\u91cd\u7a0b\u5ea6\uff0c\u4ee5\u53caGVHD\u7684\u53d1\u751f\u7387\u548c\u4e25\u91cd\u7a0b\u5ea6\u3002\u800c\u6765\u81ea\u5065\u5eb7\u6350\u8d60\u8005\u7684FMT\u5728\u6062\u590d\u6709\u76ca\u7ec6\u83cc\u65b9\u9762\u662f\u5426\u4f1a\u50cf\u75c5\u4eba\u81ea\u5df1\u7684\u7caa\u4fbf\u6837\u672c\u4e00\u6837\u6709\u76ca\uff0c\u8fd8\u6709\u5f85\u8fdb\u4e00\u6b65\u7814\u7a76\u3002<\/span><\/p>\n


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\u53c2\u8003\u8d44\u6599\uff1a<\/span><\/strong>1\uff09<\/span>Fecal microbiota transplantation helps restore beneficial bacteria in cancer patients<\/span><\/p>\n

2\uff09Reconstitution of the gut microbiota of antibiotic-treated patients by autologous fecal microbiota transplant<\/span><\/p>\n

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\u672c\u6587\u7cfb\u751f\u7269\u63a2\u7d22\u539f\u521b\uff0c\u6b22\u8fce\u4e2a\u4eba\u8f6c\u53d1\u5206\u4eab\u3002\u5176\u4ed6\u4efb\u4f55\u5a92\u4f53\u3001\u7f51\u7ad9\u5982\u9700\u8f6c\u8f7d\uff0c\u987b\u5728\u6b63\u6587\u524d\u6ce8\u660e\u6765\u6e90\u751f\u7269\u63a2\u7d22\u3002<\/span><\/p>\n<\/section>\n

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\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

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