{"id":56876,"date":"2018-09-26T01:00:00","date_gmt":"2018-09-30T02:19:10","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/09\/30\/%e5%b0%8f%e7%a5%9e%e8%8d%af%e8%85%ba%e8%8b%b7%e8%99%bd%e5%a5%bd%ef%bc%8c%e4%bd%86%e8%a6%81%e6%b3%a8%e6%84%8f%e8%bf%99%e4%ba%9b%e9%97%ae%e9%a2%98%ef%bc%81\/"},"modified":"2018-09-30T10:19:11","modified_gmt":"2018-09-30T02:19:11","slug":"%e5%b0%8f%e7%a5%9e%e8%8d%af%e8%85%ba%e8%8b%b7%e8%99%bd%e5%a5%bd%ef%bc%8c%e4%bd%86%e8%a6%81%e6%b3%a8%e6%84%8f%e8%bf%99%e4%ba%9b%e9%97%ae%e9%a2%98%ef%bc%81","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/56876\/","title":{"rendered":"\u201c\u5c0f\u795e\u836f\u201d\u817a\u82f7\u867d\u597d\uff0c\u4f46\u8981\u6ce8\u610f\u8fd9\u4e9b\u95ee\u9898\uff01"},"content":{"rendered":"
\n

\"\u201c\u5c0f\u795e\u836f\u201d\u817a\u82f7\u867d\u597d\uff0c\u4f46\u8981\u6ce8\u610f\u8fd9\u4e9b\u95ee\u9898\uff01\"<\/p>\n

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\u4f5c\u8005\uff1a\u4f55\u91d1\u5c71<\/span><\/p>\n

\u6765\u6e90\uff1a\u533b\u5b66\u754c\u5fc3\u8840\u7ba1\u9891\u9053<\/span><\/p>\n


<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\u817a\u82f7<\/span><\/strong>\u4e5f\u7b97\u662f\u5fc3\u5185\u79d1\u7684\u201c\u5c0f\u795e\u836f\u201d\u4e4b\u4e00\uff0c\u6709\u5ba4\u4e0a\u901f\u7684\u5730\u65b9\uff0c\u5c31\u6709\u5b83\u7684\u8eab\u5f71\uff0c\u88ab\u817a\u82f7\u7ec8\u6b62\u7684\u5ba4\u4e0a\u901f\uff0c\u53ef\u80fd\u548c\u88ab\u785d\u9178\u7518\u6cb9\u7f13\u89e3\u7684\u80f8\u75db\u4e00\u6837\u591a\u3002<\/span><\/p>\n

<\/span><\/p>\n

\"\u201c\u5c0f\u795e\u836f\u201d\u817a\u82f7\u867d\u597d\uff0c\u4f46\u8981\u6ce8\u610f\u8fd9\u4e9b\u95ee\u9898\uff01\"<\/p>\n


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1<\/span><\/section>\n
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 <\/span>\u6765\uff0c\u4e00\u8d77\u6df1\u5165\u4e86\u89e3\u5c0f\u795e\u836f\u201c\u817a\u82f7\u201d<\/span><\/section>\n<\/section>\n
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\u817a\u82f7\uff0c\u5168\u79f0\u817a\u560c\u5464\u6838\u82f7\u9178\uff0c\u5728\u4f53\u5185\u7684\u6765\u6e90\u4e3b\u8981\u6709\u4e24\u4e2a\uff1a<\/span><\/p>\n


<\/span><\/p>\n

    \n
  • \n

    ATP<\/span><\/strong><\/span>\uff08\u4e09\u78f7\u9178\u817a\u82f7\uff0c\u6ca1\u9519\uff0c\u5c31\u662f\u90a3\u4e2a\u80fd\u91cf\u6ee1\u6ee1\u7684ATP\uff09\u8131\u78f7\u9178\u540e\u8f6c\u5316\u4e3aADP\uff0c\u518d\u8131\u78f7\u9178\u8f6c\u5316\u4e3aADP\uff0c\u518d\u8131\u78f7\u9178\u8f6c\u5316\u4e3aAMP\uff0c\u8131\u6389\u5168\u90e8\u7684\u78f7\u9178\u540e\u5373\u8f6c\u5316\u6210\u4e86<\/span>\u817a\u82f7<\/span><\/strong>\uff0c\u817a\u82f7\u5c31\u662fATP\u4e00\u8131\u518d\u8131\u7684\u7ed3\u679c<\/strong>\u3002<\/span><\/p>\n<\/li>\n<\/ul>\n


    <\/span><\/p>\n

      \n
    • \n

      \u53e6\u5916\u4e00\u4e2a\u6765\u6e90\u662f\u4f53\u5185\u7684<\/span>S\u817a\u82f7\u540c\u578b\u534a\u80f1\u6c28\u9178<\/strong><\/span>\u5728\u9176\u7684\u5206\u89e3\u4f5c\u7528\u4e0b\uff0c\u8f6c\u5316\u6210\u817a\u82f7\u548c\u540c\u578b\u534a\u80f1\u6c28\u9178\u3002\u800c\u4f53\u5185\u7684\u817a\u82f7\uff0c\u591a\u6570\u4f1a\u628a\u8131\u53bb\u7684\u78f7\u9178\u4e00\u4e2a\u4e2a\u518d\u201c\u6361\u201d\u56de\u6765\uff0c\u8f6c\u5316\u4e3aAMP\u3001ADP\u53caATP\uff0c\u8fdb\u5165\u4e00\u4e2a\u9006\u5411\u7684\u5faa\u73af\uff0c\u6240\u8c13\u4ece\u54ea\u91cc\u6765\uff0c\u53c8\u56de\u5230\u54ea\u91cc\u53bb\u3002\u5c11\u90e8\u5206\u7684\u817a\u82f7\uff0c\u4f1a\u5206\u89e3\u6210\u9ec4\u560c\u5464\u548c\u6b21\u9ec4\u560c\u5464\uff0c\u6700\u7ec8\u8f6c\u5316\u4e3a\u5c3f\u9178\u3002<\/span><\/p>\n<\/li>\n<\/ul>\n


      <\/span><\/p>\n

      \u817a\u82f7\u7684\u4f5c\u7528\u901a\u8fc7\u548c\u817a\u82f7\u53d7\u4f53\u7ed3\u5408\u800c\u5b8c\u6210\uff0c\u4f53\u5185\u4e3b\u8981\u5b58\u57283\u79cd\u817a\u82f7\u53d7\u4f53<\/span><\/strong>\uff1a<\/span><\/p>\n

        \n
      • \n

        \u817a\u82f7\u7684\u7535\u751f\u7406\u6548\u5e94\uff0c\u4e3b\u8981\u548cA1\u53d7\u4f53<\/strong>\u6709\u5173\uff0c\u5305\u62ec\u964d\u4f4e\u7aa6\u623f\u7ed3\u81ea\u5f8b\u6027\u3001\u6291\u5236\u623f\u5ba4\u7ed3\u7684\u4f20\u5bfc\u7b49\u3002<\/span><\/p>\n<\/li>\n

      • \n

        A2\u578b\u53d7\u4f53\u4e3b\u8981\u548c\u8840\u7ba1\u6269\u5f20\u6709\u5173\uff0c\u5e94\u7528\u817a\u82f7\u540e\u5bfc\u81f4\u7684\u80f8\u95f7\u3001\u9762\u90e8\u6f6e\u7ea2\u7b49\u5373\u548c\u6b64\u76f8\u5173\u3002<\/strong><\/span><\/p>\n<\/li>\n

      • \n

        A3\u578b\u53d7\u4f53\u548c\u817a\u82f7\u8bf1\u53d1\u54ee\u5598\u6709\u5173\uff0c\u8fd9\u4e5f\u662f\u817a\u82f7\u5e94\u7528\u7684\u7981\u5fcc\u4e4b\u4e00<\/strong><\/span>\u3002<\/strong><\/span><\/p>\n<\/li>\n<\/ul>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


        <\/span><\/p>\n

        \u817a\u82f7\u548cA1\u53d7\u4f53\u7ed3\u5408\u540e\uff0c\u4f1a\u6291\u5236cAMP\u3001G\u86cb\u767d\u548c\u513f\u8336\u915a\u80fa\uff0c\u4fc3\u8fdbK+\u5916\u6d41\uff0c\u6291\u5236Ca2+\u5185\u6d41\uff0c\u4ece\u800c\u8d77\u5230\u964d\u4f4e\u7aa6\u623f\u7ed3\u81ea\u5f8b\u6027\uff0c\u6291\u5236\u7aa6\u623f\u4f20\u5bfc\uff0c\u7f29\u77ed\u5fc3\u623f\u52a8\u4f5c\u7535\u4f4d\u65f6\u7a0b\uff0c\u5f15\u8d77\u623f\u5ba4\u4f20\u5bfc\u963b\u6ede\u7b49\u4e00\u7cfb\u5217\u7684\u4f5c\u7528\u3002\u7531\u4e8e\u817a\u82f7\u5bf9cAMP\u3001G\u86cb\u767d\u7b49\u6709\u7740\u660e\u663e\u7684\u6291\u5236\u4f5c\u7528\uff0c\u8fd9\u4e9b\u56e0\u5b50\u548c\u89e6\u53d1\u6d3b\u52a8\u6709\u7740\u5bc6\u5207\u7684\u8054\u7cfb\uff0c\u800c\u67d0\u4e9b\u7279\u53d1\u6027\u5ba4\u901f\u673a\u5236\u6070\u597d\u4e3a\u89e6\u53d1\u6d3b\u52a8\uff0c\u56e0\u800c\u817a\u82f7\u4e5f\u53ef\u7ec8\u6b62\u90e8\u5206\u5ba4\u901f\u3002<\/span><\/p>\n


        <\/p>\n

        \u5f53\u7136\uff0c\u7531\u4e8e\u817a\u82f7\u5bf9\u623f\u5ba4\u7ed3\u7684\u5f3a\u70c8\u800c\u660e\u786e\u7684\u4f5c\u7528\uff0c<\/strong><\/span>\u5176\u6700\u4e3a\u8457\u540d\u7684\u8fd8\u662f\u7ec8\u6b62\u623f\u5ba4\u7ed3\u4f9d\u8d56\u7684\u5ba4\u4e0a\u6027\u5fc3\u52a8\u8fc7\u901f<\/strong><\/span>\u3002<\/strong>\u5bf9\u4e8e\u623f\u901f\u6216\u8005\u623f\u6251\uff0c\u817a\u82f7\u5373\u4f7f\u4e0d\u80fd\u7ec8\u6b62\u5176\u53d1\u4f5c\uff0c\u4f46\u53ef\u51cf\u5c11\u623f\u5ba4\u4f20\u5bfc\uff0c\u663e\u9732P\u6ce2\u6216F\u6ce2\uff0c\u534f\u52a9\u660e\u786e\u8bca\u65ad\u3002<\/span><\/p>\n


        <\/p>\n

        \n
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        \n
        2<\/span><\/section>\n
        <\/section>\n<\/section>\n<\/section>\n
         \u90a3\u4e48\uff0c\u5982\u4f55\u4f7f\u7528\u5462\uff1f<\/span><\/section>\n<\/section>\n
        <\/section>\n<\/section>\n


        <\/p>\n<\/section>\n

        \u817a\u82f7\u4e4b\u6240\u4ee5\u6210\u4e3a\u201c\u795e\u836f\u201d\uff0c\u4e0d\u5355\u662f\u5176\u80fd\u591f\u7ec8\u6b62\u5ba4\u4e0a\u901f\uff0c\u4e5f\u56e0\u4e3a\u5176\u8d77\u4f5c\u7528\u5f88\u5feb\uff0c\u817a\u82f7\u5728\u4eba\u4f53\u5185\u7684\u534a\u8870\u671f\u53ea\u670910s\u5de6\u53f3\uff0c\u9759\u63a8\u65f6\u9700\u8981\u57285s\u5b8c\u6210\uff0c\u91c7\u7528\u56e2\u6ce8\u5f0f\u7684\u65b9\u5f0f\uff0c\u201c\u600e\u4e00\u4e2a\u5feb\u5b57\u4e86\u5f97\u201d<\/strong>\uff0c\u9759\u63a8\u8fc7\u817a\u82f7\u540e\uff0c\u591a\u6570\u7684\u5ba4\u4e0a\u901f\u53ef\u572830s\u5185\u7ec8\u6b62\uff0c\u6548\u679c\u7acb\u7aff\u89c1\u5f71\u3002<\/span>\u66f4\u4e3a\u91cd\u8981\u7684\uff0c\u8fd9\u4e2a\u836f\u7269\uff0c\u5373\u4f7f\u5728\u5b55\u5987\u8fd9\u7c7b\u7279\u6b8a\u4eba\u7fa4\u4e2d\uff0c\u4e5f\u80fd\u5e94\u7528\u3002<\/span><\/p>\n


        <\/span><\/p>\n

        \u817a\u82f7\u53ef\u6309\u71670.1-0.25 mg\/kg\u7684\u65b9\u5f0f\u7ed9\u836f\uff0c\u4f46\u4e34\u5e8a\u66f4\u591a\u9009\u62e9\u4ece\u5c0f\u5242\u91cf\u5f00\u59cb<\/strong>\u2014\u20146mg\uff0c\u5982\u4e0d\u80fd\u7ec8\u6b62\uff0c1\u5206\u949f\u540e\u6539\u4e3a12mg\uff0c\u5982\u4ecd\u4e0d\u80fd\u7ec8\u6b62\uff0c\u589e\u52a0\u81f318mg\uff0c<\/span>\u5408\u5e76\u9ad8\u5ea6\u623f\u5ba4\u4f20\u5bfc\u963b\u6ede\u540e\uff0c\u4e0d\u5efa\u8bae\u7ee7\u7eed\u8ffd\u52a0\u817a\u82f7\u7684\u5242\u91cf<\/strong><\/span>\u3002<\/span><\/p>\n


        <\/span><\/p>\n

        \u817a\u82f7\u4fdd\u5b58\u56f0\u96be\uff0c\u76ee\u524d\u5f88\u591a\u533b\u9662\u5e94\u7528\u7684\u662fATP\uff0cATP\u7528\u6cd5\u548c\u817a\u82f7\u7c7b\u4f3c\uff0c10mgATP\u4f5c\u7528\u548c6mg\u817a\u82f7\u76f8\u5f53\u3002<\/span><\/p>\n

         <\/span><\/p>\n

        \n
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        3<\/span><\/section>\n
        <\/section>\n<\/section>\n<\/section>\n
         \u795e\u836f\u867d\u597d\uff0c\u4e5f\u8981\u683c\u5916\u6ce8\u610f\uff01<\/span><\/section>\n<\/section>\n
        <\/section>\n<\/section>\n


        <\/p>\n<\/section>\n

        \u817a\u82f7\u867d\u597d\uff0c\u786c\u8d77\u6765\u5374\u8981\u683c\u5916\u5f53\u5fc3\uff0c10s\u5de6\u53f3\u7684\u534a\u8870\u671f\u5185\uff0c\u53d1\u751f\u7684\u53ef\u662f\u201c\u5929\u7ffb\u5730\u8986\u201d\u7684\u53d8\u5316\u3002<\/span><\/p>\n


        <\/span><\/p>\n

        <\/span><\/p>\n

        \n
        <\/section>\n<\/section>\n
        \n
        \n
        \n


        <\/p>\n

          \n
        • \n

          \u5907\u597d\u9664\u98a4\u5668\u548c\u4e34\u65f6\u8d77\u640f\u5668\uff1a<\/strong><\/span>\u5907\u597d\u9664\u98a4\u5668\u548c\u8d77\u640f\uff0c\u5907\u597d\u9664\u98a4\u5668\u548c\u8d77\u640f\uff0c\u91cd\u8981\u7684\u4e8b\u60c5\u8bf43\u904d\uff0c\u817a\u82f7\u7ec8\u6b62\u5ba4\u4e0a\u901f\u7528\u7684\u5c31\u662f\u5b83\u5bf9\u623f\u5ba4\u7ed3\u7684\u6291\u5236\u4f5c\u7528\uff0c\u4f46\u817a\u82f7\u5bf9\u7aa6\u623f\u7ed3\u548c\u623f\u5ba4\u7ed3\u540c\u65f6\u5177\u6709\u6291\u5236\u4f5c\u7528\uff0c\u800c\u4e14\u8c01\u80fd\u4fdd\u8bc1\u706b\u5019\u62ff\u634f\u7684\u90a3\u4e48\u51c6\u786e\uff0c\u4e0d\u4f1a\u4ea7\u751f\u8fc7\u591a\u7684\u6291\u5236\u4f5c\u7528\u5462\uff0c\u4e07\u4e00\u5bf9\u7aa6\u623f\u7ed3\u548c\u623f\u5ba4\u7ed3\u7684\u6291\u5236\u4f5c\u7528\u8fc7\u5f3a\uff0c\u52bf\u5fc5\u4f1a\u4ea7\u751f\u5fc3\u5ba4\u505c\u640f\uff0c\u8fd9\u5728\u4e34\u5e8a\u5e76\u4e0d\u5c11\u89c1\uff0c\u56e0\u800c\u505a\u597d\u8d77\u640f\u548c\u9664\u98a4\u7684\u51c6\u5907\uff0c\u662f\u4fdd\u8bc1\u60a3\u8005\u5e94\u7528\u817a\u82f7\u751f\u547d\u5b89\u5168\u7684\u5173\u952e\u3002<\/span><\/p>\n<\/li>\n<\/ul>\n


          <\/span><\/p>\n

            \n
          • \n

            \u9762\u90e8\u6f6e\u7ea2\u3001\u80f8\u95f7\u3001\u547c\u5438\u56f0\u96be\uff1a<\/strong><\/span>\u8fd9\u4e3b\u8981\u548c\u817a\u82f7\u7684\u6269\u8840\u7ba1\u4f5c\u7528\u4ee5\u53ca\u5f15\u8d77\u77ed\u6682\u7684\u652f\u6c14\u7ba1\u6536\u7f29\u6709\u5173\uff0c\u591a\u6570\u572830s\u5185\u81ea\u884c\u7f13\u89e3\uff0c\u505a\u597d\u89e3\u91ca\u548c\u5b89\u6170\u7684\u5de5\u4f5c\u5373\u53ef\u3002<\/span><\/p>\n<\/li>\n<\/ul>\n


            <\/span><\/p>\n

              \n
            • \n

              \u6d3b\u52a8\u6027\u54ee\u5598\u60a3\u8005\u7981\u7528\uff1a<\/strong><\/span>\u817a\u82f7\u9664\u4e86\u4f5c\u7528\u5728A1\u53d7\u4f53\u5916\uff0c\u8fd8\u53ef\u4f5c\u7528\u4e8eA3\u53d7\u4f53\uff0c\u5f15\u8d77\u53ca\u52a0\u91cd\u54ee\u5598\uff0c\u56e0\u800c\u6d3b\u52a8\u6027\u54ee\u5598\u60a3\u8005\uff0c\u7981\u7528\u817a\u82f7\u3002<\/span><\/p>\n<\/li>\n<\/ul>\n


              <\/span><\/p>\n

                \n
              • \n

                \u4e25\u91cd\u4e3b\u52a8\u8109\u74e3\u72ed\u7a84\u3001\u4e3b\u52a8\u8109\u74e3\u53cd\u6d41\u548c\u4f4e\u8840\u538b\u7684\u60a3\u8005\u614e\u7528\uff1a<\/strong><\/span>\u817a\u82f7\u5177\u6709\u5f3a\u70c8\u7684\u6269\u8840\u7ba1\u4f5c\u7528\uff0c\u5bf9\u4e8e\u9759\u8109\u7684\u660e\u663e\u6269\u5f20\u4f5c\u7528\uff0c\u53ef\u5bfc\u81f4\u56de\u5fc3\u8840\u91cf\u660e\u663e\u51cf\u5c11\uff0c\u5728\u4e25\u91cd\u4e3b\u52a8\u8109\u74e3\u72ed\u7a84\u53ca\u53cd\u6d41\u7684\u60a3\u8005\u4e2d\uff0c\u53ef\u5f71\u54cd\u5230\u51a0\u8109\u7684\u5173\u6ce8\uff0c\u4f7f\u5fc3\u810f\u4f9b\u8840\u4e0d\u8db3\uff0c\u5728\u4e25\u91cd\u4f4e\u8840\u538b\u60a3\u8005\u4e2d\uff0c\u53ef\u5bfc\u81f4\u8840\u538b\u8fdb\u4e00\u6b65\u964d\u4f4e\uff0c\u751a\u81f3\u5bfc\u81f4\u4f11\u514b\uff0c\u56e0\u800c\u5728\u8fd9\u4e9b\u60a3\u8005\u4e2d\uff0c\u817a\u82f7\u5e94\u7528\u9700\u683c\u5916\u614e\u91cd\u3002<\/span><\/p>\n<\/li>\n<\/ul>\n<\/section>\n<\/section>\n<\/section>\n


                <\/span><\/strong><\/p>\n


                <\/span><\/strong><\/p>\n

                \u4e86\u89e3\u817a\u82f7\u7684\u8fd9\u4e9b\u4e8b\uff0c<\/span><\/strong><\/p>\n

                \u5e0c\u671b\u6211\u4eec\u90fd\u80fd\u6210\u4e3a\u9a7e\u9a6d\u8fd9\u4e2a\u201c\u5c0f\u795e\u836f\u201d\u7684\u80fd\u624b\uff01<\/span><\/strong><\/p>\n


                <\/p>\n

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                <\/span><\/p>\n

                1.Headrick JP, AshtonKJ, Rose\u2019meyer RB, Peart JN. Cardiovascular adenosinereceptors: expression, actions and interactions. Pharmacol Ther. 2013;140:92\u2013111.<\/span><\/p>\n

                2. Lerman BB,Belardinelli L. Cardiac electrophysiology of adenosine. Basic and clinicalconcepts. Circulation. 1991;83:1499\u20131509.<\/span><\/p>\n

                3. Lerman BB,Belardinelli L. Effects of adenosine on ventricular tachycardia. In: Pellig A,Michelson EL. Dreifus LS, eds. Cardiac Electrophysiology and Pharmacology ofAdenosine and ATP: Basic and Clinical Aspects. New York: Alan R. Liss; 1987:310\u2013314.<\/span><\/p>\n

                4. Cheung JW, IpJE, Yarlagadda RK, Liu CF, Thomas G, Xu L, Wilkes D, Markowitz SM, Lerman BB.Adenosine-insensitive right ventricular tachycardia: novel variant ofidiopathic outflow tract tachycardia. Heart Rhythm. 2014;11:1770\u20131778.<\/span><\/p>\n

                <\/span>
                <\/p>\n

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