{"id":57174,"date":"2018-11-29T17:17:38","date_gmt":"2018-11-29T09:17:38","guid":{"rendered":"http:\/\/www.05921.net\/?p=57174"},"modified":"2018-11-29T17:27:20","modified_gmt":"2018-11-29T09:27:20","slug":"%e6%8a%97%e7%99%8c%e8%8d%af%e7%89%a9vitrakvi%e7%be%8e%e5%9b%bd%e4%b8%8a%e5%b8%82%ef%bc%81%e4%b8%93%e5%ae%b6%e8%a1%a8%e7%a4%ba%e5%ae%83%e5%8f%aa%e9%80%82%e7%94%a8%e4%ba%8e%e8%bf%99%e4%b8%80%e9%83%a8","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/57174\/","title":{"rendered":"\u6297\u764c\u836f\u7269Vitrakvi\u7f8e\u56fd\u4e0a\u5e02\uff01\u4e13\u5bb6\u8868\u793a\u5b83\u53ea\u9002\u7528\u4e8e\u8fd9\u4e00\u90e8\u5206\u4eba\u7fa4\uff01"},"content":{"rendered":"<p style=\"text-align: left;\">\u00a0 \u00a0 \u6700\u8fd1\u7684\u670b\u53cb\u5708\u91cc\uff0c\u662f\u4e0d\u662f\u88ab\u300a\u91cd\u5927\u7a81\u7834\uff01 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href=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/11\/640-2.jpg\"><img loading=\"lazy\" class=\"alignnone size-full wp-image-57181\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/11\/640-2.jpg\" alt=\"\" width=\"897\" height=\"887\" srcset=\"https:\/\/www.05921.net\/wp-content\/uploads\/2018\/11\/640-2.jpg 897w, https:\/\/www.05921.net\/wp-content\/uploads\/2018\/11\/640-2-300x297.jpg 300w, https:\/\/www.05921.net\/wp-content\/uploads\/2018\/11\/640-2-768x759.jpg 768w\" sizes=\"(max-width: 897px) 100vw, 897px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<section class=\"\" style=\"border: 0px none; box-sizing: border-box;\" data-tools=\"135\u7f16\u8f91\u5668\" data-id=\"93685\">\n<section style=\"text-align: center; margin: 11px 0% 10px; box-sizing: border-box;\">\n<section style=\"display: inline-block; width: 100%; vertical-align: top; border-radius: 0px; padding-right: 10px; padding-bottom: 10px; padding-left: 10px; box-shadow: #000000 0px 0px 0px; box-sizing: border-box; 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237, 0.0980392);\">\n<section class=\"\">\n<p style=\"font-family: 'Helvetica Neue', Helvetica, 'Hiragino Sans GB', 'Microsoft YaHei', Arial, sans-serif; font-size: medium; line-height: 25.6px;\"><span style=\"font-size: 15px;\">Bayer(\u62dc\u8033)\u548cLoxoOncology\u516c\u53f8\u8054\u5408\u5ba3\u5e03\uff0c\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40(FDA)\u5df2\u52a0\u901f\u6279\u51c6Vitrakvi\u7684\u4e0a\u5e02\u65f6\u95f4\u3002\u62dc\u8033\u62ab\u9732\u7684\u4fe1\u606f\u663e\u793a\uff0cVitrakvi\u572817\u79cd\u80bf\u7624\u7c7b\u578b\u4e2d\u663e\u793a\u51fa\u4e34\u5e8a\u83b7\u76ca\uff0c\u5305\u62ec\u80ba\u764c\u3001\u7532\u72b6\u817a\u764c\u3001\u9ed1\u8272\u7d20\u7624\u3001\u7ed3\u80a0\u764c\u3001\u8f6f\u7ec4\u7ec7\u8089\u7624\u3001\u6d8e\u817a\u80bf\u7624\u548c\u5a74\u513f\u7ea4\u7ef4\u8089\u7624\u7b49\u3002<br \/>\n<\/span><\/p>\n<p style=\"font-family: 'Helvetica Neue', Helvetica, 'Hiragino Sans GB', 'Microsoft YaHei', Arial, sans-serif; font-size: medium; line-height: 25.6px;\"><span style=\"font-size: 15px;\">\u8be5\u6297\u764c\u836f\u53ef\u7528\u4e8e\u6cbb\u7597\u643a\u5e26NTRK\u57fa\u56e0\u878d\u5408\u7684\u6210\u4eba\u548c\u513f\u7ae5\uff0c\u9002\u7528\u4e8e\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u5b9e\u4f53\u7624\uff0c\u5e76\u4e14\u6ca1\u6709\u4ea7\u751f\u5df2\u77e5\u7684\u6297\u6027\u7a81\u53d8\uff0c\u800c\u624b\u672f\u5207\u9664\u98ce\u9669\u8f83\u5927\uff0c\u6ca1\u6709\u6709\u6548\u66ff\u4ee3\u6cbb\u7597\u65b9\u6848\u7684\u3002\u5728\u6cbb\u7597TRK\u57fa\u56e0\u878d\u5408\u80bf\u7624\u60a3\u8005\u7684\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0cVitrakvi\u7684\u603b\u4f53\u7f13\u89e3\u7387\u4e3a75%\uff0c\u5176\u4e2d22%\u7684\u60a3\u8005\u8fbe\u5230\u5b8c\u5168\u7f13\u89e3\uff0c53%\u4e3a\u90e8\u5206\u7f13\u89e3\u3002<\/span><\/p>\n<p style=\"font-family: 'Helvetica Neue', Helvetica, 'Hiragino Sans GB', 'Microsoft YaHei', Arial, sans-serif; font-size: medium; line-height: 25.6px;\"><span style=\"font-size: 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border-box;\">\n<section style=\"box-sizing: border-box;\">\n<section style=\"display: inline-block; min-width: 10%; max-width: 100%; vertical-align: top; padding: 3px 10px 6px 20px; border-radius: 0px; box-sizing: border-box; border: 1px solid #3e3e3e;\">\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: left; margin-right: 0%; margin-left: 0%; box-sizing: border-box; transform: translate3d(-30px, 0px, 0px); -webkit-transform: translate3d(-30px, 0px, 0px); -moz-transform: translate3d(-30px, 0px, 0px); -ms-transform: translate3d(-30px, 0px, 0px); -o-transform: translate3d(-30px, 0px, 0px);\">\n<section style=\"display: inline-block; width: 20px; height: 30px; vertical-align: top; overflow: hidden; background-color: #ffffff; box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: center; margin-right: 0%; margin-left: 0%; box-sizing: border-box;\">\n<section style=\"max-width: 100%; vertical-align: middle; display: inline-block; width: 100%; box-sizing: border-box;\" data-width=\"100%\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\">\n<section style=\"margin-top: -25px; margin-right: 0%; margin-left: 0%; box-sizing: border-box; transform: translate3d(1px, 0px, 0px); -webkit-transform: translate3d(1px, 0px, 0px); -moz-transform: translate3d(1px, 0px, 0px); -ms-transform: translate3d(1px, 0px, 0px); -o-transform: translate3d(1px, 0px, 0px);\">\n<section style=\"box-sizing: border-box; color: #ffa900; padding-right: 10px; padding-left: 10px;\">\n<section class=\"\" data-brushtype=\"text\"><span style=\"font-family: 'Helvetica Neue', Helvetica, 'Hiragino Sans GB', 'Microsoft YaHei', Arial, sans-serif; line-height: 24px; font-size: 15px;\">\u79d1\u666e<\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p>\u901a\u4fd7\u6765\u8bf4\uff0cTRK\u662f\u8c03\u8282\u7ec6\u80de\u901a\u8baf\u548c\u80bf\u7624\u751f\u957f\u7684\u91cd\u8981\u4fe1\u53f7\u901a\u8def\uff0c\u800cNTRK\u662f\u7f16\u7801TRK\u7684\u57fa\u56e0\u3002<\/p>\n<p>\u5728\u7f55\u89c1\u60c5\u51b5\u4e0b\uff0cNTRK\u57fa\u56e0\u4f1a\u4e0e\u5176\u5b83\u57fa\u56e0\u878d\u5408\uff0c\u5bfc\u81f4TRK\u4fe1\u53f7\u901a\u8def\u4e0d\u53d7\u63a7\u5236\uff0c\u53d1\u751f\u7a81\u53d8\uff0c\u4ece\u800c\u4fc3\u8fdb\u80bf\u7624\u7684\u751f\u957f\u3002<\/p>\n<p>Vitrakvi\u6709\u591a\u5927\u6548\u679c<\/p>\n<p>\u9002\u7528\u8303\u56f4\uff1a\u80ba\u764c\u3001\u7532\u72b6\u817a\u764c\u3001\u9ed1\u8272\u7d20\u7624\u7b4917\u79cd\u80bf\u7624<\/p>\n<p>\u9002\u7528\u5e74\u9f84\uff1a\u5a74\u513f\u81f3\u8001\u5e74\u4eba\u5747\u53ef\u9002\u7528<\/p>\n<p>\u9650\u5236\u6761\u4ef6\uff1a\u9002\u7528\u7531\u5355\u4e00\u7f55\u89c1\u57fa\u56e0\u7a81\u53d8\u9a71\u52a8\u7684\u5404\u79cd\u764c\u75c7\u60a3\u8005<\/p>\n<p>\u6548\u679c\uff1a\u4f7f\u7528\u8be5\u836f\u7269\u7684\u60a3\u8005\uff0c\u670975%\u7684\u60a3\u8005\u80bf\u7624\u80fd\u7f29\u5c0f30%\u7684\u6bd4\u4f8b<\/p>\n<p>\u7ef4\u6301\u65f6\u95f4\uff1a\u7ea66\u4e2a\u6708\u81f39\u4e2a\u6708<\/p>\n<p>\u6279\u53d1\u8d39\u7528\uff1a\u6210\u4eba\uff0c32800\u7f8e\u5143\uff0c30\u5929\u7528\u91cf\u3002\u513f\u7ae5\uff0c\u8d77\u4ef7\u4e3a\u6bcf\u670811000\u7f8e\u5143\uff0c\u6839\u636e\u60a3\u8005\u7684\u8868\u9762\u79ef\u8ba1\u7b97<\/p>\n<p><a href=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/11\/640.jpg\"><img loading=\"lazy\" class=\"alignnone size-full wp-image-57177\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/11\/640.jpg\" alt=\"\" width=\"1080\" height=\"577\" srcset=\"https:\/\/www.05921.net\/wp-content\/uploads\/2018\/11\/640.jpg 1080w, https:\/\/www.05921.net\/wp-content\/uploads\/2018\/11\/640-300x160.jpg 300w, https:\/\/www.05921.net\/wp-content\/uploads\/2018\/11\/640-768x410.jpg 768w, https:\/\/www.05921.net\/wp-content\/uploads\/2018\/11\/640-1024x547.jpg 1024w\" sizes=\"(max-width: 1080px) 100vw, 1080px\" \/><\/a><\/p>\n<section style=\"box-sizing: border-box; border: 0px none;\">\n<section style=\"text-align: center; margin: 10px 0%; box-sizing: border-box;\">\n<section style=\"display: inline-block; min-width: 10%; max-width: 100%; vertical-align: top; padding-right: 10px; padding-left: 10px; border-width: 0px; box-sizing: border-box;\">\n<section style=\"box-sizing: 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inline-block; width: 100%; box-sizing: border-box;\" data-width=\"100%\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\">\n<section style=\"margin-top: -25px; margin-right: 0%; margin-left: 0%; box-sizing: border-box; transform: translate3d(1px, 0px, 0px); -webkit-transform: translate3d(1px, 0px, 0px); -moz-transform: translate3d(1px, 0px, 0px); -ms-transform: translate3d(1px, 0px, 0px); -o-transform: translate3d(1px, 0px, 0px);\">\n<section style=\"box-sizing: border-box; color: #ffa900; padding-right: 10px; padding-left: 10px;\">\n<section class=\"\" data-brushtype=\"text\"><span style=\"font-family: 'Helvetica Neue', Helvetica, 'Hiragino Sans GB', 'Microsoft YaHei', Arial, sans-serif; line-height: 24px; font-size: 15px;\">\u91ca\u7591<\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p><strong>1.\u53ea\u6709\u6781\u5c11\u6570\u60a3\u8005\u80fd\u4eab\u53d7\u6cbb\u7597\u6548\u679c<\/strong><\/p>\n<p>Vitrakvi\u6297\u764c\u836f\u7269\u51fa\u6765\u540e\uff0c\u7f51\u4f20\u8fd9\u6b3e\u836f\u53ef\u6cbb\u759717\u79cd\u80bf\u7624\uff0c\u6cbb\u6108\u7387\u8fbe75%\u3002\u771f\u7684\u6709\u8fd9\u4e48\u795e\u5947\u5417?\u5bf9\u6b64\uff0c\u6709\u8bb0\u8005\u91c7\u8bbf\u4e86<strong>\u6e56\u5357\u7701\u7b2c\u4e8c\u4eba\u6c11\u533b\u9662\u80bf\u7624\u79d1\u4e3b\u4efb\u5510\u4e09\u5143\u4e3b\u4efb\u533b\u5e08\u3002<\/strong><\/p>\n<p>\u5510\u4e09\u5143\u4ecb\u7ecd\uff0c\u80bf\u7624\u7531\u5f88\u591a\u57fa\u56e0\u7a81\u53d8\u5bfc\u81f4\uff0c\u65b0\u836f\u5bf9\u7279\u5b9a\u7684\u57fa\u56e0\u878d\u5408\u80bf\u7624\u60a3\u8005\u6709\u6548\u679c\uff0c\u4f46\u5bf9\u5176\u4ed6\u56e0\u57fa\u56e0\u7a81\u53d8\u9020\u6210\u7684\u80bf\u7624\u60a3\u8005\u4e0d\u4e00\u5b9a\u6709\u6548\u3002\u201c\u5b83\u98a0\u8986\u4e86\u4ee5\u524d\u80bf\u7624\u6cbb\u7597\u7684\u7406\u5ff5\u3002\u201d\u5510\u4e09\u5143\u8bf4\uff0c\u4ee5\u524d\u764c\u75c7\u7684\u6cbb\u7597\u65b9\u6cd5\u57fa\u4e8e\u4eba\u4f53\u8d77\u6e90\u7ec4\u7ec7\uff0c\u6bd4\u5982\u9488\u5bf9\u80a0\u764c\u3001\u80ba\u764c\u6709\u4e0d\u540c\u7684\u6cbb\u6cd5\u3002\u5982\u4eca\u662f\u57fa\u4e8e\u5206\u5b50\u7c7b\u578b\u6765\u6cbb\u7597\u80bf\u7624\uff0c\u8fd9\u662f\u672a\u6765\u8d8b\u52bf\uff0c\u4e5f\u662f\u5411\u7cbe\u51c6\u533b\u7597\u8fc8\u51fa\u7684\u91cd\u5927\u4e00\u6b65\u3002\u8fd9\u79cd\u65b0\u836f\u4e0d\u9700\u8981\u8003\u8651\u764c\u75c7\u7684\u53d1\u751f\u90e8\u4f4d\uff0c\u4e0e\u80bf\u7624\u7ec4\u7ec7\u65e0\u5173\uff0c\u201c\u8fd9\u610f\u5473\u7740\uff0c\u4e0d\u7ba1\u4ec0\u4e48\u764c\u79cd\uff0c\u53ea\u8981\u6709NTRK\u57fa\u56e0\u878d\u5408\uff0c\u5c31\u53ef\u4ee5\u4f7f\u7528Vitrakvi\u8fdb\u884c\u6cbb\u7597\u201d\u3002<\/p>\n<p>\u5510\u4e09\u5143\u4ecb\u7ecd\uff0c\u76ee\u524d\uff0c\u5e02\u9762\u4e0a\u6709\u5404\u79cd\u9776\u5411\u836f\uff0c\u6bcf\u79cd\u9776\u5411\u836f\u591a\u6570\u662f\u9488\u5bf9\u67d0\u4e00\u79cd\u57fa\u56e0\uff0c\u5982\u679c\u627e\u5230\u9a71\u52a8\u57fa\u56e0\uff0c\u4e5f\u5c31\u662f\u5bfc\u81f4\u7ec6\u80de\u53d1\u751f\u764c\u53d8\u7684\u5173\u952e\u57fa\u56e0\uff0c\u5c31\u80fd\u53d6\u5f97\u540c\u6837\u7684\u6cbb\u7597\u6548\u679c\uff0c\u201c\u8fd9\u79cd\u836f\u6210\u529f\u7684\u5730\u65b9\u5c31\u662f\uff0c\u5bf9\u591a\u79cd\u80bf\u7624\u90fd\u6709\u5f88\u597d\u7684\u6548\u679c\u201d\u3002<\/p>\n<p>\u201c\u4f46\u4e25\u683c\u6765\u8bf4\uff0cVitrakvi\u4e0d\u80fd\u79f0\u4e3a\u2018\u5e7f\u8c31\u6297\u764c\u836f\u2019\u3002\u201d\u5510\u4e09\u5143\u8bf4\uff0c\u5e7f\u8c31\u6297\u764c\u836f\u6307\u7684\u662f\u6cbb\u7597\u7684\u7624\u79cd\u6bd4\u8f83\u591a\uff0c\u800cVitrakvi\u53d1\u6325\u4f5c\u7528\u7684\u524d\u63d0\uff0c\u662f\u5355\u4e00\u7f55\u89c1\u57fa\u56e0\u7a81\u53d8\u9a71\u52a8\u7684\u5404\u79cd\u764c\u75c7\u60a3\u8005\uff0c\u201cVitrakvi\u53ef\u6709\u6548\u5bf9\u6297\u7531\u5355\u4e00\u7f55\u89c1\u57fa\u56e0\u7a81\u53d8\u9a71\u52a8\u7684\u5404\u79cd\u764c\u75c7\uff0c\u4f46\u8fd9\u79cd\u7a81\u53d8\u5728\u5927\u591a\u6570\u5b9e\u4f53\u80bf\u7624\u4e2d\u53d1\u751f\u7684\u51e0\u7387\u6bd4\u8f83\u4f4e\uff0c\u5728\u6211\u56fd\u764c\u75c7\u60a3\u8005\u4e2d\u53605%\u4ee5\u4e0b\u3002\u201d<\/p>\n<p>\u5510\u4e09\u5143\u4ecb\u7ecd\uff0c\u5224\u65ad\u8fd9\u79cd\u65b0\u836f\u662f\u5426\u9002\u5408\uff0c\u60a3\u8005\u5148\u9700\u8981\u505a\u57fa\u56e0\u68c0\u6d4b\uff0c\u660e\u786e\u662f\u5426\u5b58\u5728\u8fd9\u4e2a\u57fa\u56e0\u878d\u5408\u7a81\u53d8\u3002\u5982\u679c\u6709\uff0c\u53ef\u80fd\u4f1a\u53d1\u6325\u4f5c\u7528\u3002\u4ed6\u8bf4\uff0c\u76ee\u524d\u56fd\u5185\u4e5f\u6709\u516c\u53f8\u5728\u505a\u7c7b\u4f3c\u836f\u7269TRK\u6291\u5236\u5242\u7684\u7814\u53d1\u548c\u4e34\u5e8a\u7814\u7a76\uff0c\u6682\u65f6\u8fd8\u6ca1\u6709\u4e0a\u5e02\u3002<\/p>\n<p><strong>2.\u603b\u4f53\u7f13\u89e3\u7387\u4e0d\u610f\u5473\u7740\u603b\u4f53\u6cbb\u6108\u7387<\/strong><\/p>\n<p>\u9488\u5bf9Vitrakvi\u5bf9\u764c\u75c7\u7684\u6cbb\u6108\u7387\u8fbe75%\u7684\u8bf4\u6cd5\uff0c\u5510\u4e09\u5143\u4e5f\u8fdb\u884c\u4e86\u89e3\u91ca\u3002<\/p>\n<p>\u4ed6\u8868\u793a\uff0c\u8fd9\u6b3e\u836f\u5e76\u4e0d\u662f\u8bf4\u80fd\u653b\u514b\u764c\u75c7\uff0c\u5b83\u53ea\u662f\u4e00\u4e2a\u65b0\u7684\u9776\u5411\u836f\u7269\u3002\u8be5\u836f\u7269\u7684\u603b\u7f13\u89e3\u738775%\u4e0d\u610f\u5473\u7740\u6cbb\u6108\u7387\u8fbe75%\u3002\u6240\u8c13\u7684\u603b\u4f53\u7f13\u89e3\u7387\uff0c\u662f\u4f7f\u7528\u836f\u54c1\u540e\u80bf\u7624\u7f29\u5c0f\u8fbe\u523030%\u4ee5\u4e0a\u7684\u60a3\u8005\u5360\u603b\u60a3\u8005\u7684\u6bd4\u4f8b\u3002<\/p>\n<p>\u7528\u4e86\u8fd9\u6b3e\u836f\u7684\u60a3\u8005\u4e2d\uff0c\u670975%\u7684\u60a3\u8005\u80bf\u7624\u80fd\u7f29\u5c0f30%\u7684\u6bd4\u4f8b\uff0c\u7ef4\u6301\u65f6\u95f4\u7ea66\u4e2a\u6708\u81f39\u4e2a\u6708\uff0c\u201c\u8fd9\u53ea\u662f\u8bf4\u5728\u6297\u51fb\u80bf\u7624\u7684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[&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":57177,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[6,7],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/57174"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=57174"}],"version-history":[{"count":3,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/57174\/revisions"}],"predecessor-version":[{"id":57183,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/57174\/revisions\/57183"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/57177"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=57174"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=57174"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=57174"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}