{"id":57823,"date":"2018-11-16T01:00:00","date_gmt":"2018-12-07T02:27:32","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/12\/07\/93f975a51d\/"},"modified":"2018-12-07T10:27:36","modified_gmt":"2018-12-07T02:27:36","slug":"93f975a51d","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/57823\/","title":{"rendered":"\u533b\u836f\u4f20\u5947 | \u4e00\u4e2a\u4f1f\u5927\u7684\u5206\u5b50"},"content":{"rendered":"
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\u4e09\u5e74\u4e86\uff0c\u4e0e\u60a8\u6709\u4e2a\u7ea6\u4f1a<\/a>
<\/strong><\/span><\/p>\n

\"\u533b\u836f\u4f20\u5947<\/span><\/span><\/a><\/p>\n


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1999\u5e74\u6ce8\u5b9a\u662f\u4e0d\u5e73\u51e1\u7684\u4e00\u5e74\u3002<\/span>
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21\u4e16\u7eaa\u7684\u5149\u8292\u8fd1\u5728\u54ab\u5c3a\u3001\u4e16\u754c\u6bc1\u706d\u7684\u9884\u8a00\u8fd8\u751a\u56a3\u5c18\u4e0a\uff0c\u5728\u4e00\u7247\u5e0c\u671b\u4e0e\u6000\u7591\u5e76\u5b58\u7684\u5174\u594b\u4e2d\uff0c\u6ca1\u4eba\u6ce8\u610f\u5230\u5728\u9ed8\u6c99\u4e1c\u7684\u7f8e\u56fd\u7814\u53d1\u603b\u90e8\uff0c\u4e24\u4f4d\u5973\u79d1\u5b66\u5bb6\u5403\u4e86\u4e00\u987f\u5bfb\u5e38\u7684\u5348\u9910\u3002<\/span><\/p>\n


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\"\u533b\u836f\u4f20\u5947<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u5348\u9910\u662fNancy Thornberry\u53d1\u8d77\u7684\u3002\u5979\u5728\u9ed8\u6c99\u4e1c\u4efb\u804c\u521a\u6ee120\u5468\u5e74\uff0c\u65f6\u4efb\u9176\u5b66\u7814\u7a76\u7684\u8d1f\u8d23\u4eba\u3002\u4e00\u4e9b\u5173\u4e8e\u4e8c\u80bd\u57fa\u80bd\u9176-4\uff08DPP-4\uff09\u6291\u5236\u5242\u7684\u62a5\u9053\u5f15\u8d77\u4e86\u5979\u7684\u5174\u8da3\u3002<\/span>[1]<\/span><\/p>\n


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\u5728\u5f53\u65f6\uff0c\u6709\u5173DPP-4\u7684\u7814\u7a76\u6b63\u5904\u4e8e\u8d77\u6b65\u9636\u6bb5\uff0c\u5df2\u6709\u52a8\u7269\u8bd5\u9a8c\u8868\u660e\uff0cDPP-4\u6291\u5236\u5242\u5177\u6709\u8c03\u8282\u8840\u7cd6\u7684\u6548\u679c\u3002Nancy\u654f\u9510\u5730\u610f\u8bc6\u5230\uff0c\u8fd9\u53ef\u80fd\u4e3a\u7cd6\u5c3f\u75c5\u6cbb\u7597\u6253\u5f00\u65b0\u7684\u5c40\u9762\u3002[2]<\/span><\/span><\/p>\n


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Nancy\u627e\u5230\u5348\u9910\u7684\u53d7\u9080\u8005\u2014\u2014Ann Weber\uff0c\u5e76\u544a\u8bc9\u5979\u81ea\u5df1\u7684\u60f3\u6cd5\u3002Ann\u662f\u54c8\u4f5b\u5927\u5b66\u7684\u9ad8\u6750\u751f\uff0c\u5728\u9ed8\u6c99\u4e1c\u5df2\u670912\u5e74\u3002\u5de7\u5408\u7684\u662f\uff0cAnn\u4e5f\u5728\u5bfb\u627e\u65b0\u7684\u7814\u7a76\u8bfe\u9898\u3002\u4e24\u4eba\u4e00\u62cd\u5373\u5408\uff0c\u51b3\u5b9a\u5411\u516c\u53f8\u7533\u8bf7\uff0c\u628aDPP-4\u6291\u5236\u5242\u4f5c\u4e3a\u4e0b\u4e00\u4e2a\u7814\u7a76\u76ee\u6807\u3002<\/span>[2]<\/span>
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\"\u533b\u836f\u4f20\u5947<\/p>\n

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Ann E. Weber\uff08\u5de6\uff09\u548cNancy A. Thornberry \uff08\u53f3\uff09<\/span><\/p>\n


<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\"\u533b\u836f\u4f20\u5947<\/span><\/p>\n

\u4e0d\u8fc7\uff0c\u60f3\u5728\u533b\u836f\u516c\u53f8\u5f00\u5c55\u836f\u7269\u7814\u7a76\u53ef\u4e0d\u5bb9\u6613\u3002<\/span>\u4e00\u9897\u65b0\u836f\u7684\u80cc\u540e\u5f80\u5f80\u662f\u5341\u4f59\u5e74\u7684\u7814\u53d1\u5386\u7a0b\uff0c\u4e5d\u6210\u4ee5\u4e0a\u7684\u7814\u7a76\u4f1a\u4ee5\u5931\u8d25\u544a\u7ec8\uff0c\u516c\u53f8\u4e5f\u5c06\u4e3a\u6b64\u652f\u4ed8\u5341\u591a\u4ebf\u7f8e\u5143\u7684\u5de8\u989d\u82b1\u9500\u3002<\/span><\/strong>\u9762\u5bf9\u9ad8\u6602\u7684\u7814\u53d1\u6210\u672c\uff0c\u65e0\u8bba\u54ea\u5bb6\u516c\u53f8\u90fd\u4f1a\u53cd\u590d\u6743\u8861\u3002<\/span><\/p>\n


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\u4f46\u8fd9\u6b21\uff0c\u9ed8\u6c99\u4e1c\u7ba1\u7406\u5c42\u5f88\u5feb\u5c31\u6279\u51c6\u4e86Nancy\u548cAnn\u7684\u7533\u8bf7\uff0c\u56e0\u4e3a\u5728\u5f53\u65f6\uff0c\u7cd6\u5c3f\u75c5\u6b63\u5728\u6210\u4e3a\u7f8e\u56fd\u4e43\u81f3\u5168\u7403\u7684\u5065\u5eb7\u96be\u9898\u3002[2]<\/span><\/span><\/p>\n


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\u201c\u867d\u7136\u5f88\u591a\u836f\u7269\u76f8\u7ee7\u51fa\u73b0\uff0c\u4f46\u8d77\u7801\u6709\u4e00\u534a\u7684\u60a3\u8005\u8840\u7cd6\u63a7\u5236\u6c34\u5e73\u5e76\u4e0d\u7406\u60f3\uff0c\u4ed6\u4eec\u6025\u9700\u65b0\u7684\u836f\u7269\u3002\u201d (Nancy Thornberry) <\/span><\/p>\n

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\u4e3a\u4e86\u6ee1\u8db3\u5e7f\u5927\u60a3\u8005\u7684\u9700\u6c42\uff0c\u9ed8\u6c99\u4e1c\u8c03\u914d\u5404\u65b9\u8d44\u6e90\uff0c\u7ed9\u4e88\u7814\u53d1\u56e2\u961f\u6781\u5927\u7684\u652f\u6301\u3002\u8ba9\u79d1\u5b66\u5bb6\u4eec\u62e5\u6709\u5145\u5206\u7684\u65bd\u5c55\u7a7a\u95f4\uff0c\u628a\u5979\u4eec\u7684\u521b\u60f3\u4ed8\u8bf8\u5b9e\u8df5\u3002<\/span><\/p>\n


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\"\u533b\u836f\u4f20\u5947<\/span><\/p>\n

\u7136\u800c\uff0c\u7814\u7a76\u521a\u521a\u542f\u52a8\uff0c\u6ee1\u8154\u70ed\u60c5\u7684Nancy\u548cAnn\u5c31\u88ab\u6d47\u4e86\u4e00\u5934\u51b7\u6c34\u3002<\/span><\/p>\n


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\u201c\u5728\u52a8\u7269\u8bd5\u9a8c\u9636\u6bb5\uff0c\u524d\u56db\u5468\u4e00\u5207\u90fd\u5f88\u597d\uff0c\u4f46\u662f\u5230\u4e86\u7b2c\u4e94\u5468\uff0c\u53d7\u8bd5\u52a8\u7269\u7a81\u7136\u5f00\u59cb\u6b7b\u53bb\uff0c\u60c5\u51b5\u771f\u7684\u5f88\u7cdf\u7cd5\u3002\u201d (Ann Weber)<\/span><\/p>\n


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\u6bd2\u7406\u5b66\u7814\u7a76\u5931\u8d25\uff0c\u610f\u5473\u7740\u8fd9\u4e2a\u5206\u5b50\u6beb\u65e0\u6210\u4e3a\u65b0\u836f\u7684\u4ef7\u503c\u548c\u53ef\u80fd\u6027\u3002\u901a\u5e38\u60c5\u51b5\u4e0b\uff0c\u6574\u4e2a\u7814\u7a76\u9879\u76ee\u90fd\u53ef\u80fd\u5c31\u6b64\u6d41\u4ea7\u3002\u5e78\u597d\u5728\u8fd9\u4e2a\u65f6\u5019\uff0c\u9ed8\u6c99\u4e1c\u7684\u7ba1\u7406\u5c42\u518d\u6b21\u5c55\u73b0\u51fa\u4ed6\u4eec\u7684\u5353\u8bc6\u548c\u8010\u5fc3\uff0c\u652f\u6301\u79d1\u5b66\u5bb6\u4eec\u63a2\u7d22\u5931\u8d25\u80cc\u540e\u7684\u539f\u56e0\u3002<\/span><\/p>\n


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\"\u533b\u836f\u4f20\u5947<\/p>\n

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\u6700\u7ec8\uff0c\u7814\u53d1\u56e2\u961f\u53d1\u73b0\u5931\u8d25\u6e90\u4e8e\u4ed6\u4eec\u4e00\u5f00\u59cb\u4f7f\u7528\u7684DPP-4\u6291\u5236\u5242\u4e0d\u5177\u6709\u9009\u62e9\u6027\uff0c\u5f53\u4ed6\u4eec\u66ff\u6362\u6210\u53e6\u4e00\u79cd\u5177\u6709\u9009\u62e9\u6027\u7684DPP-4\u6291\u5236\u5242\u540e\uff0c\u52a8\u7269\u8bd5\u9a8c\u6210\u529f\u4e86\u3002[2]<\/span><\/span><\/p>\n


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\u201c\u5f53\u65f6\u6211\u5728\u82f1\u56fd\uff0c\u56e0\u4e3a\u53d1\u751f\u4e86911\u4e8b\u4ef6\uff0c\u6240\u6709\u56de\u7f8e\u56fd\u7684\u822a\u73ed\u90fd\u53d6\u6d88\u4e86\u3002\u6211\u6ede\u7559\u5728\u4f26\u6566\uff0c\u7279\u522b\u62c5\u5fc3\u7ebd\u7ea6\u7684\u670b\u53cb\u548c\u5bb6\u4eba\u3002\u8fd9\u65f6\u5019Nancy\u6253\u6765\u7535\u8bdd\uff0c\u544a\u8bc9\u6211\u8bd5\u9a8c\u7ed3\u679c\u5f88\u597d\uff0c\u6211\u4eec\u53ef\u4ee5\u8fc8\u51fa\u4e0b\u4e00\u6b65\u4e86\uff0c\u6240\u6709\u4eba\u90fd\u611f\u5230\u5f88\u632f\u594b\u3002\u201d (Ann Weber) <\/span><\/span>[3]<\/span><\/p>\n


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\"\u533b\u836f\u4f20\u5947<\/span><\/p>\n

\u51ed\u501f\u575a\u97e7\u7684\u5b9e\u9a8c\u7cbe\u795e\uff0c\u79d1\u5b66\u5bb6\u4eec\u514b\u670d\u91cd\u91cd\u56f0\u96be\uff0c\u5728\u5206\u5b50\u7684\u6d77\u6d0b\u4e2d\u4e0d\u65ad\u63a2\u7d22\u3002\u5728\u4e00\u6b21\u6b21\u8bc4\u4f30\u53ef\u884c\u6027\u3001\u9501\u5b9a\u76ee\u6807\u5206\u5b50\u3001\u63ed\u793a\u751f\u7269\u5b66\u539f\u7406\u3001\u8bb0\u5f55\u8bd5\u9a8c\u7ec6\u8282\u7684\u8fc7\u7a0b\u4e2d\uff0c\u4ed6\u4eec\u4e00\u6b65\u6b65\u5411\u7b54\u6848\u9760\u8fd1\u3002<\/span><\/p>\n


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\u5728\u627e\u5230\u5408\u9002\u7684\u5206\u5b50\u524d\uff0c\u79d1\u5b66\u5bb6\u4eec\u4e00\u5171\u7b5b\u9009\u4e862,000\u591a\u4e2a\u5316\u5408\u7269\u3002\u6574\u4e2a\u7814\u53d1\u9879\u76ee\u4e2d\uff0c\u8d85\u8fc710,000\u79cd\u5316\u5408\u7269\u88ab\u9074\u9009\u3001\u8bbe\u8ba1\u548c\u6d4b\u8bd5\u8fc7 <\/span><\/span><\/strong>[2]<\/span>\u3002<\/span><\/strong>\u6700\u540e\u7684\u83b7\u9009\u8005\uff0c\u65e0\u7591\u662f\u79d1\u5b66\u5bb6\u4eec\u5343\u6311\u4e07\u9009\u3001\u5728\u65e0\u6570\u9053\u4fee\u9970\u548c\u8bba\u8bc1\u4e0b\u6253\u78e8\u800c\u6210\u7684\u827a\u672f\u54c1\uff0c\u7528Nancy\u548cAnn\u7684\u8bdd\u8bf4\uff0c<\/span><\/p>\n

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\u201c\u8fd9\u662f\u4e00\u4e2a\u4f1f\u5927\u7684\u5206\u5b50\u3002\u201d<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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2006\u5e74\uff0c\u5168\u7403\u9996\u4e2aDPP-4\u6291\u5236\u5242\u5728\u7f8e\u56fd\u83b7\u5f97FDA\u6279\u51c6\uff0c\u5f00\u8f9f\u4e86\u4e8c\u578b\u7cd6\u5c3f\u75c5\u6cbb\u7597\u7684\u4e00\u4e2a\u5168\u65b0\u54c1\u7c7b\uff0c\u7cd6\u5c3f\u75c5\u6cbb\u7597\u4ece\u6b64\u7ffb\u5f00\u65b0\u7684\u7bc7\u7ae0\u3002<\/span><\/strong><\/p>\n


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\u56de\u987eDPP-4\u6291\u5236\u5242\u7684\u8bde\u751f\uff0cNancy\u548cAnn\u628a\u5979\u4eec\u7684\u6210\u529f\u5f52\u4e8e\u516d\u70b9\uff1a<\/span><\/p>\n


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    \u575a\u97e7\u7684\u8bd5\u9a8c\u7cbe\u795e<\/span><\/p>\n<\/li>\n

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    \u4eb2\u5bc6\u7684\u56e2\u961f\u5408\u4f5c<\/span><\/p>\n<\/li>\n<\/ul>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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    \u8fd9\u4e00\u5207\u8ba9DPP-4\u6291\u5236\u5242\u7684\u7814\u53d1\u8fdb\u5c55\u795e\u901f\uff0c\u6253\u7834\u4e86\u9ed8\u6c99\u4e1c\u65e2\u5f80\u7814\u53d1\u65b0\u836f\u7684\u8bb0\u5f55\uff0c\u4e5f\u8ba9\u516c\u53f8\u548c\u79d1\u5b66\u5bb6\u8f7d\u8a89\u800c\u5f52\uff1a<\/span>
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    2007\u5e74\uff0c\u9ed8\u6c99\u4e1c\u7814\u53d1\u56e2\u961f\u88ab\u6388\u4e88\u201c\u76d6\u4f26\u5956\u201d\uff08Prix Galien\uff09<\/span><\/p>\n

    2010\u5e74\uff0cNancy\u548cAnn\u83b7\u5f97\u7f8e\u56fd\u5316\u5b66\u5b66\u4f1a\u201c\u5316\u5b66\u82f1\u96c4\u5956\u201d\uff08Heroes of Chemistry\uff09<\/span><\/p>\n

    2011\u5e74\uff0cNancy\u548cAnn\u83b7\u5f97\u533b\u7a76\u4e0e\u5236\u9020\u5546\u534f\u4f1a\u201c\u53d1\u73b0\u8005\u5927\u5956\u201d\uff08Discoverers Award\uff09<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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    \u800c\u5728\u4e24\u4f4d\u79d1\u5b66\u5bb6\u770b\u6765\uff0c\u6240\u6709\u7684\u5149\u73af\u548c\u8363\u8a89\uff0c\u90fd\u6bd4\u4e0d\u4e0a\u8fd9\u4e2a\u4f1f\u5927\u7684\u5206\u5b50\u7ed9\u4e16\u754c\u5e26\u6765\u7684\u6539\u53d8\u8ba9\u5979\u4eec\u9ad8\u5174\uff1a<\/span><\/span><\/strong><\/p>\n

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    <\/span><\/strong><\/p>\n

    \u201c\u6211\u4eec\u59cb\u7ec8\u5bf9\u81ea\u5df1\u7684\u4f7f\u547d\u3001\u5bf9\u7814\u53d1\u7684\u5206\u5b50\u6df1\u4fe1\u4e0d\u7591\u3002\u5f53\u6211\u7684\u540c\u4e8b\u3001\u670b\u53cb\u7684\u5988\u5988\u7eb7\u7eb7\u544a\u8bc9\u6211\u4ed6\u4eec\u4e5f\u5728\u4f7f\u7528DPP-4\u6291\u5236\u5242\u65f6\uff0c\u8fd9\u624d\u662f\u6700\u89e6\u52a8\u6211\u7684\u65f6\u523b\u3002\u201d \uff08Ann Weber)<\/strong><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

    <\/span><\/p>\n


    <\/p>\n

    \n


    <\/p>\n

    \n
    \n
    \n
    \n

    * \u672c\u6587\u4e3a\u9ed8\u6c99\u4e1c\u7814\u53d1\u6d3b\u52a8\u56de\u987e\uff0c\u4efb\u4f55\u6d89\u53ca\u4ea7\u54c1\u7684\u4fe1\u606f\u5e94\u4ee5\u6240\u5728\u56fd\u5bb6\u548c\u5730\u533a\u7ecf\u6279\u51c6\u7684\u836f\u54c1\u8bf4\u660e\u4e66\u4e3a\u51c6\u3002
    <\/span><\/p>\n


    <\/span><\/p>\n

    \u4fe1\u606f\u6765\u6e90\uff1a<\/span><\/p>\n

    [1] PhRMA, Press Release, Women Scientists Honored For New Diabetes Oral <\/span>Medication, 2013. <\/span><\/p>\n

    [2] <\/span>TEDx Talks, Youtube, Bench tobedside – discovery of JANUVIA (Sitagliptin): Ann Weber & Nancy Thornberryat TEDxNJIT, 2013.<\/span><\/span><\/p>\n

    [3] PhRMAPress, Youtube, PhRMA11 Discoverers Award Winner 2011, 2011.<\/span><\/span><\/p>\n

    \u6807\u9898\u56fe\u7247\u6765\u6e90\uff1a<\/span>
    <\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

    Wikimedia Commons, Science History Institute, Nancy A. Thornberry and Ann E. Weber, 2017.<\/span><\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

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