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style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><strong style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\uff08\u4e8c\uff09\u751f\u4ea7\u5de5\u827a<\/strong><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><strong style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/strong><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><strong style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word 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style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><strong style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">1\u3001\u6027\u72b6<\/strong><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 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style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">\u7533\u8bf7\u4eba\u53ef\u6839\u636e\u4ea7\u54c1\u7279\u70b9\uff0c\uff0c\u8bbe\u8ba1\u4e0e\u4e34\u5e8a\u5c40\u90e8\u4f5c\u7528\u76f8\u5173\u7684\u4f53\u5916\u91ca\u653e\u4e00\u81f4\u6027\u7814\u7a76\uff0c\u4ee5\u4f50\u8bc1\u836f\u7269\u4e0e\u53c2\u6bd4\u5236\u5242\u7684\u4e34\u5e8a\u7597\u6548\u4e00\u81f4\u6027\u3002<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  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style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">\u964d\u89e3\u4ea7\u7269\uff1a\u91cd\u70b9\u5bf9\u5236\u5242\u7684\u964d\u89e3\u4ea7\u7269\u8fdb\u884c\u7814\u7a76\uff0c\u5305\u62ec\u539f\u6599\u836f\u7684\u964d\u89e3\u4ea7\u7269\u6216\u8005\u539f\u6599\u836f\u4e0e\u8f85\u6599\u548c\/\u6216\u5185\u5305\u6750\u7684\u53cd\u5e94\u4ea7\u7269\uff0c\u5206\u6790\u539f\u6599\u836f\u964d\u89e3\u9014\u5f84\u3002\u539f\u6599\u836f\u7684\u5de5\u827a\u6742\u8d28\u4e00\u822c\u4e0d\u9700\u5728\u5236\u5242\u4e2d\u8fdb\u884c\u76d1\u6d4b\u6216\u8bf4\u660e\u3002<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: 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style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><strong style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5341\u4e00\u3001\u836f\u7406\u6bd2\u7406\u7814\u7a76\u7684\u6280\u672f\u8981\u6c42<\/strong><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: 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style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><strong style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5341\u4e8c\u3001\u7b49\u6548\u6027\u8bc4\u4ef7\u65b9\u6cd5<\/strong><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: 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style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">2\u3001\u5728\u4eff\u5236\u836f\u4e0e\u53c2\u6bd4\u5236\u5242\u7684\u5173\u952e\u8d28\u91cf\u5c5e\u6027\uff08Q3\uff09\u4e00\u81f4\u7684\u524d\u63d0\u4e0b\uff0c\u82e5\u8f85\u6599\u79cd\u7c7b\uff08Q1\uff09\u76f8\u540c\u3001\u8f85\u6599\u7528\u91cf\uff08Q2\uff09\u4e0d\u76f8\u4f3c\uff0c\u6216\u4eff\u5236\u836f\u4e0e\u53c2\u6bd4\u5236\u5242\u7684\u8f85\u6599\u79cd\u7c7b\uff08Q1\uff09\u4e0d\u540c\uff0c\u5219\u5e94\u8fdb\u884c\u4ee5\u53c2\u6bd4\u5236\u5242\u4e3a\u5bf9\u7167\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4ee5\u652f\u6301\u4eff\u5236\u54c1\u4e0e\u539f\u7814\u54c1\u5728\u4e34\u5e8a\u5b89\u5168\u6709\u6548\u6027\u65b9\u9762\u7684\u4e00\u81f4\u6027\u3002\u3002<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><strong style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\uff08\u4e8c\uff09\u9634\u9053\u6813<\/strong><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">1\u3001\u82e5\u4eff\u5236\u836f\u4e0e\u53c2\u6bd4\u5236\u5242\u7684\u8f85\u6599\uff08\u4e0d\u5305\u62ec\u6291\u83cc\u5242\u3001\u6297\u6c27\u5242\uff09\u79cd\u7c7b\uff08Q1\uff09\u76f8\u540c\uff0c\u8f85\u6599\u7528\u91cf\uff08Q2\uff09\u76f8\u4f3c\uff0c\u5173\u952e\u8d28\u91cf\u5c5e\u6027\uff08Q3\uff09\u4e00\u81f4\uff0c\u5e76\u8fdb\u884c\u4e86\u4e0e\u4e34\u5e8a\u5c40\u90e8\u4f5c\u7528\u76f8\u5173\u7684\u4f53\u5916\u91ca\u653e\u4e00\u81f4\u6027\u7814\u7a76\uff08\u5982\u6a21\u62df\u9634\u9053\u5236\u5242\u4f53\u5185\u91ca\u653e\u884c\u4e3a\u7684\u4f53\u5916\u91ca\u653e\u7814\u7a76\u7b49\uff09\uff0c\u7ecf\u6570\u636e\u8bc4\u4f30\u8bc1\u660e\u4f53\u5916\u91ca\u653e\u884c\u4e3a\u76f8\u4f3c\uff0c\u5219\u53ef\u4ee5\u63d0\u51fa\u8c41\u514d\u4e34\u5e8a\u7533\u8bf7\uff1b\u5982\u672a\u8bc1\u660e\u4f53\u5916\u91ca\u653e\u884c\u4e3a\u76f8\u4f3c\uff0c\u5219\u5e94\u8fdb\u884c\u4ee5\u53c2\u6bd4\u5236\u5242\u4e3a\u5bf9\u7167\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4ee5\u652f\u6301\u4eff\u5236\u54c1\u4e0e\u539f\u7814\u54c1\u5728\u4e34\u5e8a\u5b89\u5168\u6709\u6548\u6027\u65b9\u9762\u7684\u4e00\u81f4\u6027\u3002<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">2\u3001\u5728\u4eff\u5236\u836f\u4e0e\u53c2\u6bd4\u5236\u5242\u7684\u5173\u952e\u8d28\u91cf\u5c5e\u6027\uff08Q3\uff09\u4e00\u81f4\uff0c\u4e14\u57fa\u8d28\u79cd\u7c7b\u76f8\u540c\u3001\u57fa\u8d28\u7528\u91cf\u76f8\u4f3c\u7684\u524d\u63d0\u4e0b\uff0c\u82e5\u5176\u4ed6\u8f85\u6599\uff08\u4e0d\u5305\u62ec\u6291\u83cc\u5242\u3001\u6297\u6c27\u5242\uff09\u7684\u79cd\u7c7b\uff08Q1\uff09\u76f8\u540c\u3001\u8f85\u6599\u7528\u91cf\uff08Q2\uff09\u4e0d\u76f8\u4f3c\uff0c\u6216\u5176\u4ed6\u8f85\u6599\uff08\u4e0d\u5305\u62ec\u6291\u83cc\u5242\u3001\u6297\u6c27\u5242\uff09\u7684\u79cd\u7c7b\uff08Q1\uff09\u4e0d\u540c\uff0c\u5219\u5e94\u8fdb\u884c\u4ee5\u53c2\u6bd4\u5236\u5242\u4e3a\u5bf9\u7167\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4ee5\u652f\u6301\u4eff\u5236\u54c1\u4e0e\u539f\u7814\u54c1\u5728\u4e34\u5e8a\u5b89\u5168\u6709\u6548\u6027\u65b9\u9762\u7684\u4e00\u81f4\u6027\u3002<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><strong style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\uff08\u4e09\uff09\u5176\u4ed6<\/strong><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">1\u3001\u5bf9\u4e8e\u53ef\u80fd\u5b58\u5728\u5c40\u90e8\u7ed9\u836f\u7cfb\u7edf\u5438\u6536\u7684\u9ad8\u98ce\u9669\u5236\u5242\uff0c\u8fd8\u9700\u8fdb\u884c\u4ee5PK\u4e3a\u7ec8\u70b9\u7684BE\u7814\u7a76\uff0c\u4ee5\u8bc1\u660e\u53d7\u8bd5\u5236\u5242\u7684\u5168\u8eab\u66b4\u9732\u4e0d\u9ad8\u4e8e\u539f\u7814\u5236\u5242<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">2\u3001\u5bf9\u4e8e\u5177\u6709\u7f13\u91ca\u4f5c\u7528\u7684\u5c40\u90e8\u5916\u7528\u5236\u5242\uff0c\u5e94\u8fdb\u884c\u4ee5\u53c2\u6bd4\u5236\u5242\u4e3a\u5bf9\u7167\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4ee5\u652f\u6301\u4eff\u5236\u54c1\u4e0e\u539f\u7814\u54c1\u5728\u4e34\u5e8a\u5b89\u5168\u6709\u6548\u6027\u65b9\u9762\u7684\u4e00\u81f4\u6027\u3002<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">3\u3001\u5bf9\u4e8e\u5176\u4ed6\u7279\u6b8a\u60c5\u51b5\uff0c\u5efa\u8bae\u5177\u4f53\u95ee\u9898\u5177\u4f53\u5206\u6790\u3002<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><strong style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5341\u4e8c\u3001\u836f\u54c1\u8bf4\u660e\u4e66\u7684\u62df\u5b9a<\/strong><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">\u5e94\u68c0\u7d22\u5e76\u8ffd\u8e2a\u53c2\u6bd4\u5236\u5242\u8bf4\u660e\u4e66\u53d8\u66f4\u60c5\u51b5\uff0c\u91c7\u7528\u6700\u65b0\u7248\u7684\u53c2\u6bd4\u5236\u5242\u8bf4\u660e\u4e66\uff0c\u62df\u5b9a\u836f\u54c1\u8bf4\u660e\u4e66\u3002<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><strong style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u53c2\u8003\u6587\u732e<\/strong><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\"><strong style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/strong><\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">[1]\u56fd\u5bb6\u836f\u5178\u59d4\u5458\u4f1a.\u4e2d\u534e\u4eba\u6c11\u5171\u548c\u56fd\u836f\u5178\uff3b\uff2d\uff3d.2015\u7248\u56db\u90e8.\u5317\u4eac:\u4e2d\u56fd\u533b\u836f\u79d1\u6280\u51fa\u7248\u793e, 2015.6.<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">[2] British Pharmacopoeia [M]. Online, 2017: General Notices&lt;1164&gt;.<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">[3] Japanese Pharmacopoeia 16[M].Online:General rules for preparations.&nbsp;<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">[4] EMA. Note for guidance on the clinical requirements for locally applied, locally acting products containing known constituents\uff08CPMP\/EWP\/239\/95\uff09.1995:http:\/\/www.emau.europa.eu.<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">[5] EMA. Guideline on equivalence studies for the demonstration of therapeutic equivalence for produces that are locally applied, locally acting in the gastrointestinal tract as addendum to the guideline on the clinical requirements for locally applied, locally acting products containing known constituents\uff08CPMP\/EWP\/239\/95 Rev.1\uff09. 2017:http:\/\/www.emau.europa.eu.<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">[6]FDA.GDUFA regulatory science program public meeting. 2015: http:\/\/www.fda.gov\/.&nbsp;<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">[7]FDA.Guidance on Topical Dermatologic Corticosteroids: in vivo bioequivalence. 1995.6.&nbsp;<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">[8] FDA.Equivalence of locally-acting drug products. 2017: http:\/\/www.fda.gov\/.<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">[9]EMA. Guideline on the investigation of bioequivalence (CPMP\/EWP\/QWP\/1401\/98 Rev.1\/Corr**). 2010.1.<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">[10]EU Clinical Trials Register. http:\/\/www.Clinical Trials Register.eu\/.<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">[11]\u5d14\u798f\u5fb7.\u300a\u836f\u5242\u5b66\uff08\u7b2c7\u7248\uff09\u300b[M].\u4eba\u6c11\u536b\u751f\u51fa\u7248\u793e.2013\u5e74.<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">[12]\u5e73\u5176\u80fd, \u5c60\u9521\u5fb7\uff0c\u5f20\u94a7\u5bff\u7b49.\u836f\u5242\u5b66. \u7b2c4\u7248[M]. \u5317\u4eac\uff1a\u4eba\u6c11\u536b\u751f\u51fa\u7248\u793e. 2013\u5e74.<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">[13]CFDA-CDE\u5ba1\u8bc4\u4e94\u90e8\u5ba1\u8bc4\u4e5d\u5ba4.\u5987\u79d1\u9634\u9053\u5c40\u90e8\u7528\u836f\u5236\u5242\u7814\u53d1\u4e2d\u5e38\u89c1\u95ee\u9898\u5206\u6790.2007.09.<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">[14] CDE.\u300a\u5316\u5b66\u4eff\u5236\u836f\u6ce8\u518c\u6279\u751f\u4ea7\u89c4\u6a21\u7684\u4e00\u822c\u6027\u8981\u6c42\uff08\u8bd5\u884c\uff09\u300b\uff082018.6.22\uff09.<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">[15]CFDA.\u300a\u5316\u5b66\u836f\u7269\uff08\u539f\u6599\u836f\u548c\u5236\u5242\uff09\u7a33\u5b9a\u6027\u7814\u7a76\u6280\u672f\u6307\u5bfc\u539f\u5219\u300b\uff082015.2.5\uff09.<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">[16] FDA.Draft guidance on miconazole nitrate\uff0ehttp:\/\/www.fda.gov\/.&nbsp;<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">[17] FDA.Draft guidance on terconazole\uff0ehttp:\/\/www.fda.gov\/.<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">[18]FDA.CDER label, TERAZOL 3-terconazole suppository. http:\/\/www.fda.gov\/.<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">[19]FDA.CDER label, MONISTAT 3-miconazole nitrate suppository. http:\/\/www.fda.gov\/.<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">[20]FDA.CDER chemistry review(s),1999: Clindamycin phosphate vaginal suppositories,100mg. http:\/\/www.fda.gov\/.\u3000<\/p>\n<p style=\"margin: 0px;padding: 0px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;clear: both;min-height: 1em;\">[21] EMA. Note for guidance on manufacture of the finished dosage form(CPMP\/QWP\/486\/95). 1996: http:\/\/www.emau.europa.eu.<\/p>\n<\/section>\n<\/section>\n<\/section>\n<p><br  \/><\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u5c40\u90e8\u4f5c\u7528\u5e38\u89c1\u9634\u9053\u5236\u5242\uff08\u9634\u9053\u7247\u3001\u9634\u9053\u6813\uff09\u4eff\u5236\u836f\u7684\u8bc4\u4ef7\u6280\u672f\u8981\u6c42 (\u5f81\u6c42\u610f\u89c1\u7a3f) \u4e00\u3001\u672c\u6280\u672f\u8981\u6c42\u4ec5\u9488\u5bf9\u65b0\u6ce8\u518c\u5206\u7c7b4\u53ca [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":58135,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/58134"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=58134"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/58134\/revisions"}],"predecessor-version":[{"id":58136,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/58134\/revisions\/58136"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/58135"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=58134"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=58134"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=58134"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}