{"id":60337,"date":"2018-11-19T01:00:00","date_gmt":"2018-12-07T02:55:56","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/12\/07\/d216fcc5ed\/"},"modified":"2018-12-07T10:55:59","modified_gmt":"2018-12-07T02:55:59","slug":"d216fcc5ed","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/60337\/","title":{"rendered":"\u56fd\u5185\u8111\u5352\u4e2d\u5728\u7814\u836f\u7269\u8fdb\u5c55\u4e00\u89c8"},"content":{"rendered":"
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\u4e00\u3001\u6700\u65b0\u4e2d\u56fdIND,\u6765\u81ea\u70df\u53f0\u76ca\u8bfa\u4f9d\uff1a<\/span><\/section>\n
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\u836f\u54c1\u7c7b\u578b<\/span><\/p>\n<\/td>\n

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\u7533\u8bf7\u7c7b\u578b<\/span><\/p>\n<\/td>\n

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\u6ce8\u518c\u5206\u7c7b<\/span><\/p>\n<\/td>\n

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\u4f01\u4e1a\u540d\u79f0<\/span><\/p>\n<\/td>\n

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\u627f\u529e\u65e5\u671f<\/span><\/p>\n<\/td>\n<\/tr>\n

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CXHL1800183<\/span><\/p>\n<\/td>\n

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Y-2\u820c\u4e0b\u7247<\/span><\/p>\n<\/td>\n

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\u5316\u836f<\/span><\/p>\n<\/td>\n

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\u65b0\u836f<\/span><\/p>\n<\/td>\n

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1<\/span><\/p>\n<\/td>\n

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\u70df\u53f0\u76ca\u8bfa\u4f9d\u751f\u7269\u533b\u836f\u79d1\u6280\u6709\u9650\u516c\u53f8<\/span><\/p>\n<\/td>\n

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2018-11-12<\/span><\/p>\n<\/td>\n<\/tr>\n

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CXHL1800182<\/span><\/p>\n<\/td>\n

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\u53f3\u65cb\u83b0\u9187<\/span><\/p>\n<\/td>\n

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\u5316\u836f<\/span><\/p>\n<\/td>\n

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\u65b0\u836f<\/span><\/p>\n<\/td>\n

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1<\/span><\/p>\n<\/td>\n

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2018-11-12<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n


<\/p>\n<\/section>\n

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\"\u56fd\u5185\u8111\u5352\u4e2d\u5728\u7814\u836f\u7269\u8fdb\u5c55\u4e00\u89c8\"<\/p>\n<\/section>\n

1.Y-2\u820c\u4e0b\u7247\u4e3a\u4e00\u6b3e\u590d\u65b9\u5236\u5242\uff0c\u836f\u7269\u6d3b\u6027\u6210\u5206\u4e3a\u4f9d\u8fbe\u62c9\u5949\u548c(+)-2-<\/span>\u83b0\u9187\u3002 <\/span>Y-2<\/span>\u820c\u4e0b\u7247\u8fc5\u901f\u5d29\u89e3\u91ca\u653e\u51fa\u4f9d\u8fbe\u62c9\u5949\u548c(+)-2-<\/span>\u83b0\u9187\uff0c\u7ecf\u8fc7\u820c\u4e0b\u9ecf\u819c\u9759\u8109\u4e1b\u76f4\u63a5\u8fdb\u5165\u8840\u6db2\u5faa\u73af\uff0c\u65e0\u9996\u8fc7\u6548\u5e94\uff08first pass elimniation<\/span>\uff09\uff0c\u7136\u540e\u900f\u8fc7\u8840\u8111\u5c4f\u969c\uff08blood brain barriar<\/span>\uff0cBBB<\/span>\uff09\u5230\u8fbe\u8111\u5352\u4e2d\u60a3\u8005\u7684\u8111\u635f\u4f24\u90e8\u4f4d\uff0c\u53d1\u6325\u795e\u7ecf\u4fdd\u62a4\u4f5c\u7528\u3002  <\/span><\/p>\n


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<\/p>\n<\/section>\n

2\u3001\u7f8e\u56fdIND:<\/span><\/strong><\/p>\n

2018\u5e743<\/span>\u670814<\/span>\u65e5\uff0c\u70df\u53f0\u76ca\u8bfa\u4f9d\u751f\u7269\u533b\u836f\u79d1\u6280\u6709\u9650\u516c\u53f8\uff08\u4e0b\u7b80\u79f0\u201c\u76ca\u8bfa\u4f9d\u201d\uff09\u4e0e\u9996\u90fd\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u5317\u4eac\u5929\u575b\u533b\u9662\u5171\u540c\u7814\u53d1\u7684\u65b0\u836fY-2<\/span>\u820c\u4e0b\u7247\uff08Y-2 sublingual tablet<\/span>\uff09\u987a\u5229\u901a\u8fc7\u7f8e\u56fdFDA IND<\/span>\u7533\u8bf7\uff08IND 138332<\/span>\uff09\u3002\u8be5\u9879\u76ee\u7f8e\u56fd\u7533\u62a5\u4ee3\u7406\u516c\u53f8\u4e3aDataRevive LLC<\/span>\u3002<\/span><\/p>\n


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3\u3001\u9002\u5e94\u75c7\uff1a<\/strong><\/span><\/p>\n

Y-2 \u820c\u4e0b\u7247\u62df\u7528\u4e8e\u8111\u5352\u4e2d\u7684\u6cbb\u7597\uff0c\u5305\u62ec\u7f3a\u8840\u6027\u8111\u5352\u4e2d\u548c\u51fa\u8840\u6027\u8111\u5352\u4e2d\u3002\u76ca\u8bfa\u4f9d\u6b63\u4e0e\u7f8e\u56fd\u4f0a\u5229\u8bfa\u4f0a\u5dde\u7684OSF HealthCare<\/span>\u5408\u4f5c\u5f00\u5c55\u4e34\u5e8aI<\/span>\u671f\u8bd5\u9a8c\uff08ClinicalTrials.gov.Identifier: NCT03495206<\/span>\uff09\u3002<\/span><\/p>\n


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<\/p>\n<\/section>\n

4\u3001\u4ea7\u54c1\u76f8\u5173\u4e13\u5229\uff1a<\/strong><\/span><\/p>\n

\u4f9d\u8fbe\u62c9\u5949\u4e0e(+)-2-\u83b0\u9187\u7684\u820c\u4e0b\u7528\u836f\u7269\u7ec4\u5408\u7269\uff0cCN201610761890.7\uff0c\u4e13\u5229\u516c\u5f00\u65e5\uff1a 2018.03.09\u3002<\/span><\/p>\n


<\/p>\n

\u672c\u53d1\u660e\u516c\u5f00\u4e86\u4e00\u79cd\u4f9d\u8fbe\u62c9\u5949\u4e0e(+)-2-\u83b0\u9187\u7ec4\u5408\u7269\u820c\u4e0b\u7ed9\u836f\u5236\u5242\u53ca\u5176\u5236\u5907\u65b9\u6cd5\uff0c\u5176\u4e2d\u820c\u4e0b\u7ed9\u836f\u5236\u5242\u5305\u62ec\u4f9d\u8fbe\u62c9\u5949\u3001(+)2-<\/span>\u83b0\u9187\u3001\u8d4b\u5f62\u5242\u3001\u586b\u5145\u5242\u3001\u7c98\u5408\u5242\u3001\u5d29\u89e3\u5242\u3001\u6da6\u6ed1\u5242\u7b49\u3002\u820c\u4e0b\u7ed9\u836f\u5236\u5242\uff0c\u53ef\u4ee5\u907f\u514d\u809d\u810f\u9996\u8fc7\u6548\u5e94\uff0c\u6837\u54c1\u7a33\u5b9a\u6027\u597d\u3001\u4fbf\u4e8e\u8fd0\u8f93\u3001\u4f7f\u7528\u65b9\u4fbf\u7b49\u4f18\u70b9\u3002<\/span><\/p>\n


<\/p>\n

\"\u56fd\u5185\u8111\u5352\u4e2d\u5728\u7814\u836f\u7269\u8fdb\u5c55\u4e00\u89c8\"<\/p>\n


<\/p>\n

5.\u4e34\u5e8a\u524d\u7814\u7a76\u8868\u660e\uff0c\u5728\u72ac\u5b9e\u9a8c\u4e2d\uff0c\u820c\u4e0b\u542b\u670dY-2<\/span>\u820c\u4e0b\u7247\u540e\u8840\u6d46\u4e2d\u4f9d\u8fbe\u62c9\u5949\u548c(+)2-<\/span>\u83b0\u9187\u66b4\u9732\u91cf\u4e0e\u9759\u8109\u6ef4\u6ce8\u590d\u65b9\u4f9d\u8fbe\u62c9\u5949\u6ce8\u5c04\u6db2\u540e\u7684\u66b4\u9732\u91cf\u4e00\u81f4\u3002\u5728\u5927\u9f20\u7f3a\u8840\u6027\u8111\u5352\u4e2d\u52a8\u7269\u6a21\u578b\u4e2d\uff0c\u820c\u4e0b\u7ed9\u4e88Y-2<\/span>\u80fd\u663e\u8457\u6539\u5584\u8111\u6897\u6b7b\u9762\u79ef\uff1b\u5728\u5927\u9f20\u51fa\u8840\u6027\u8111\u5352\u4e2d\u6a21\u578b\u4e2d\uff0c\u820c\u4e0b\u7ed9\u4e88Y-2<\/span>\u80fd\u663e\u8457\u6539\u5584\u8111\u6c34\u80bf\u3001\u6539\u5584BBB<\/span>\u901a\u900f\u7387\uff0c\u6539\u5584\u6a21\u578b\u52a8\u7269\u957f\u671f\u7684\u795e\u7ecf\u529f\u80fd\u8bc4\u5206\u548c\u8fd0\u52a8\u529f\u80fd\u3002<\/span><\/p>\n


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<\/p>\n<\/section>\n

6\u3001\u516c\u53f8\u4ea7\u54c1\u7ebf\uff1a<\/span><\/strong><\/p>\n

\u5b9a\u4f4d\u4e8e\u5168\u7403\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\uff08CNS\uff09\u75be\u75c5\u521b\u65b0\u836f\u63a2\u7d22\u8005\u3002\u76ee\u524d\u5df2\u6709\u56db\u4e2a1<\/span>\u7c7b\u65b0\u836f\u8fdb\u5165\u7814\u53d1\u7ba1\u7ebf\uff0c\u5305\u62ec\u6cbb\u7597\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u836f\u7269Y-1<\/span>\u9879\u76ee\u3001\u6cbb\u7597\u8111\u5352\u4e2d\u836f\u7269Y-2<\/span>\u9879\u76ee\u3001\u6cbb\u7597\u795e\u7ecf\u75db\u836f\u7269Y-3<\/span>\u9879\u76ee\u548c\u6cbb\u7597\u7126\u8651\/<\/span>\u6291\u90c1Y-4<\/span>\u9879\u76ee\u3002<\/span><\/p>\n

\"\u56fd\u5185\u8111\u5352\u4e2d\u5728\u7814\u836f\u7269\u8fdb\u5c55\u4e00\u89c8\"<\/p>\n


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\u4e8c\u3001\u56fd\u5185\u8111\u5352\u4e2d\u9886\u57df\u5728\u7814\u836f\u7269<\/span><\/section>\n
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\u767b\u8bb0\u53f7<\/span><\/p>\n<\/td>\n

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\u8bd5\u9a8c\u72b6\u6001<\/span><\/p>\n<\/td>\n

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\u836f\u7269\u540d\u79f0<\/span><\/p>\n<\/td>\n

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\u9002\u5e94\u75c7<\/span><\/p>\n<\/td>\n

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\u4e34\u5e8a<\/span>\u8bd5\u9a8c<\/span>\u7814\u7a76<\/span>\u9898\u76ee<\/span><\/p>\n<\/td>\n<\/tr>\n

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CTR20181134<\/span><\/p>\n<\/td>\n

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\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

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\u6ce8\u5c04\u7528\u91cd\u7ec4\u4eba\u5c3f\u6fc0\u9176\u539f<\/span><\/p>\n<\/td>\n

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\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d<\/span><\/p>\n<\/td>\n

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B1101\u9759\u8109\u6eb6\u6813\u6cbb\u7597<\/span>4.5-6h\u6025\u6027\u8111\u5352\u4e2d<\/span>\u2162\u671f\u4e34\u5e8a\u8bd5\u9a8c<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n

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CTR20180766<\/span><\/p>\n<\/td>\n

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\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

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\u6ce8\u5c04\u7528\u785d\u916e\u55ea<\/span><\/p>\n<\/td>\n

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\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d<\/span><\/p>\n<\/td>\n

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\u6ce8\u5c04\u7528\u785d\u916e\u55ea\u591a\u6b21\u7ed9\u836fI\u671f\u8bd5\u9a8c<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n

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CTR20180622<\/span><\/p>\n<\/td>\n

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\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

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\u6ce8\u5c04\u7528\u91cd\u7ec4\u4eba\u5c3f\u6fc0\u9176\u539f<\/span><\/p>\n<\/td>\n

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\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d<\/span><\/p>\n<\/td>\n

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B1101\u9759\u8109\u6eb6\u6813\u6cbb\u7597<\/span>AIS\u2162a\u4e34\u5e8a\u8bd5\u9a8c<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n

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CTR20180586<\/span><\/p>\n<\/td>\n

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\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

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\u94f6\u674f\u603b\u5185\u916f\u6ef4\u4e38<\/span><\/p>\n<\/td>\n

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\u7f3a\u8840\u6027\u8111\u5352\u4e2d<\/span><\/p>\n<\/td>\n

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\u94f6\u674f\u603b\u5185\u916f\u6ef4\u4e38\u836f\u4ee3\u52a8\u529b\u5b66\u8bd5\u9a8c<\/span><\/p>\n<\/td>\n<\/tr>\n

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CTR20180545<\/span><\/p>\n<\/td>\n

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\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

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\u5421\u62c9\u683c\u96f7\u94a0\u6ce8\u5c04\u6db2<\/span><\/p>\n<\/td>\n

\n

\u6cbb\u7597\u6025\u6027\u8840\u6813\u6027\u8111\u6897\u6b7b\u548c\u8111\u6897\u6b7b\u6240\u4f34\u968f\u7684\u8fd0\u52a8\u969c\u788d<\/span><\/p>\n<\/td>\n

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\u6cbb\u7597\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d\u60a3\u8005\u7684\u6709\u6548\u6027\u548c\u5b89\u5168\u6027<\/span><\/p>\n<\/td>\n<\/tr>\n

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CTR20180447<\/span><\/p>\n<\/td>\n

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\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

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\u6ce8\u5c04\u7528\u91cd\u7ec4\u4ebaTNK\u7ec4\u7ec7\u578b\u7ea4\u6eb6\u9176\u539f\u6fc0\u6d3b\u5242<\/span><\/span><\/p>\n<\/td>\n

\n

\u7528\u4e8e\u53d1\u75c53\u5c0f\u65f6\u4e4b\u5185\u7684\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d\u7684\u6eb6\u6813\u6cbb\u7597<\/span><\/span><\/p>\n<\/td>\n

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\u94ed\u590d\u4e50\u6cbb\u7597\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d\uff08\u53d1\u75c5<3h\uff09<\/span>II\u671f\u5242\u91cf\u63a2\u7d22\u7814\u7a76<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20180172<\/span><\/p>\n<\/td>\n

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\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

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\u66ff\u683c\u745e\u6d1b\u7247<\/span><\/p>\n<\/td>\n

\n

\u6025\u6027\u8111\u5352\u4e2d\u6216\u77ed\u6682\u6027\u8111\u7f3a\u8840<\/span><\/p>\n<\/td>\n

\n

\u66ff\u683c\u745e\u6d1b\u6cbb\u7597\u6025\u6027\u8111\u5352\u4e2d\u6216\u77ed\u6682\u6027\u8111\u7f3a\u8840\u53d1\u4f5c<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20171254<\/span><\/p>\n<\/td>\n

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\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

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\u6ce8\u5c04\u7528\u5e03\u7f57\u4f50\u55b7\u94a0<\/span><\/p>\n<\/td>\n

\n

\u8f7b\u3001\u4e2d\u5ea6\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u5e03\u7f57\u4f50\u55b7\u94a0\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u53ca\u836f\u4ee3\u52a8\u529b\u5b66\u7279\u6027<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20170723<\/span><\/p>\n<\/td>\n

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\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

\n

SPT-07A\u6ce8\u5c04\u6db2<\/span><\/span><\/p>\n<\/td>\n

\n

\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d<\/span><\/p>\n<\/td>\n

\n

SPT-07A\u6ce8\u5c04\u6db2<\/span>I\u671f\u4e34\u5e8a\u8bd5\u9a8c<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20170717<\/span><\/p>\n<\/td>\n

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\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

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\u76ca\u6c14\u7184\u98ce\u80f6\u56ca<\/span><\/p>\n<\/td>\n

\n

\u7f3a\u8840\u6027\u8111\u5352\u4e2d\uff08\u6062\u590d\u671f\uff09<\/span><\/p>\n<\/td>\n

\n

TFZ16\u4eba\u4f53\u8010\u53d7\u6027<\/span>I\u671f\u4e34\u5e8a\u8bd5\u9a8c<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n

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CTR20170564<\/span><\/p>\n<\/td>\n

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\u5df2\u5b8c\u6210<\/span><\/p>\n<\/td>\n

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\u6ce8\u5c04\u7528\u785d\u916e\u55ea<\/span><\/p>\n<\/td>\n

\n

\u672c\u54c1\u62df\u7528\u4e8e\u6cbb\u7597\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d\uff0c\u53d1\u6325\u795e\u7ecf\u4fdd\u62a4\u4f5c\u7528\uff0c\u6539\u5584\u60a3\u8005\u7684\u65e5\u5e38\u751f\u6d3b\u80fd\u529b\u548c\u529f\u80fd\u7f3a\u635f<\/span><\/p>\n<\/td>\n

\n

\u6ce8\u5c04\u7528\u785d\u916e\u55ea\u5355\u5242\u7ed9\u836f\u8010\u53d7\u6027\u4e0e\u836f\u4ee3\u52a8\u529b\u5b66\u8bd5\u9a8c<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20170346<\/span><\/p>\n<\/td>\n

\n

\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u9a6c\u6765\u9178\u6842\u54cc\u9f50\u7279\u6ce8\u5c04\u6db2<\/span><\/p>\n<\/td>\n

\n

\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u8bc4\u4ef7\u9a6c\u6765\u9178\u6842\u54cc\u9f50\u7279\u6ce8\u5c04\u6db2\u7684\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\u7814\u7a76<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20170218<\/span><\/p>\n<\/td>\n

\n

\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u9a6c\u6765\u9178\u6842\u54cc\u9f50\u7279\u6ce8\u5c04\u6db2<\/span><\/p>\n<\/td>\n

\n

\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u8bc4\u4ef7\u6842\u54cc\u9f50\u7279\u6cbb\u7597\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d\u7684\u7597\u6548\u53ca\u5b89\u5168\u6027<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20170178<\/span><\/p>\n<\/td>\n

\n

\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u6ce8\u5c04\u7528\u5e03\u7f57\u4f50\u55b7\u94a0<\/span><\/p>\n<\/td>\n

\n

\u8f7b\u3001\u4e2d\u5ea6\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u5e03\u7f57\u4f50\u55b7\u94a0\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u53ca\u836f\u4ee3\u52a8\u529b\u5b66\u7279\u6027<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20170152<\/span><\/p>\n<\/td>\n

\n

\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u94f6\u674f\u603b\u5185\u916f\u6ef4\u4e38<\/span><\/p>\n<\/td>\n

\n

\u7f3a\u8840\u6027\u8111\u5352\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u94f6\u674f\u603b\u5185\u916f\u6ef4\u4e38I\u671f\u8010\u53d7\u6027\u8bd5\u9a8c<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20170068<\/span><\/p>\n<\/td>\n

\n

\u5df2\u5b8c\u6210<\/span><\/p>\n<\/td>\n

\n

\u6ce8\u5c04\u7528\u5417\u5229\u798f\u80bd<\/span><\/p>\n<\/td>\n

\n

\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d\u7684\u795e\u7ecf\u4fdd\u62a4<\/span><\/p>\n<\/td>\n

\n

\u6ce8\u5c04\u7528\u5417\u5229\u798f\u80bd\u7684I\u671f\u4e34\u5e8a\u8bd5\u9a8c<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20160953<\/span><\/p>\n<\/td>\n

\n

\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u6ce8\u5c04\u7528\u91cd\u7ec4\u4eba\u5c3f\u6fc0\u9176\u539f<\/span><\/p>\n<\/td>\n

\n

\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d<\/span><\/p>\n<\/td>\n

\n

B1101\u9759\u8109\u6eb6\u6813\u6cbb\u7597<\/span>AIS\u2161a\u671f\u4e34\u5e8a\u8bd5\u9a8c<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20160947<\/span><\/p>\n<\/td>\n

\n

\u5df2\u5b8c\u6210<\/span><\/p>\n<\/td>\n

\n

\u5b89\u8111\u4e09\u9187\u6ce8\u5c04\u5242<\/span><\/p>\n<\/td>\n

\n

\u8111\u5352\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u5b89\u8111\u4e09\u9187\u6ce8\u5c04\u5242\u5728\u5065\u5eb7\u4eba\u4f53\u7684\u5b89\u5168\u6027\u8bc4\u4ef7\uff08\u591a\u6b21\uff09<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20160737<\/span><\/p>\n<\/td>\n

\n

\u5df2\u5b8c\u6210<\/span><\/p>\n<\/td>\n

\n

\u6ce8\u5c04\u7528\u963f\u66ff\u666e\u9176<\/span><\/p>\n<\/td>\n

\n

\u6025\u6027\u8111\u5352\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u963f\u66ff\u666e\u9176\u5728\u5352\u4e2d\u53d1\u4f5c\u540e3\u81f3<\/span>4.5\u5c0f\u65f6\u671f\u95f4\u6eb6\u6813\u6cbb\u7597<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20160417<\/span><\/p>\n<\/td>\n

\n

\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u9a6c\u6765\u9178\u6842\u54cc\u9f50\u7279\u6ce8\u5c04\u6db2<\/span><\/p>\n<\/td>\n

\n

\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d\u60a3\u8005<\/span><\/p>\n<\/td>\n

\n

\u6cbb\u7597\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u4e34\u5e8a\u8bd5\u9a8c<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20160292<\/span><\/p>\n<\/td>\n

\n

\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u9a6c\u6765\u9178\u6842\u54cc\u9f50\u7279\u6ce8\u5c04\u6db2<\/span><\/p>\n<\/td>\n

\n

\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u9a6c\u6765\u9178\u6842\u54cc\u9f50\u7279\u6ce8\u5c04\u6db2\u6cbb\u7597\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d\u7684\u786e\u8bc1\u8bd5\u9a8c<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20160285<\/span><\/p>\n<\/td>\n

\n

\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u5de6\u65cb\u76d0\u9178\u82ef\u73af\u58ec\u916f\u7247<\/span><\/p>\n<\/td>\n

\n

\u540e\u5faa\u73af\u7f3a\u8840\u6027\u8111\u5352\u4e2d\u6240\u81f4\u7729\u6655<\/span><\/p>\n<\/td>\n

\n

\u5de6\u65cb\u76d0\u9178\u82ef\u73af\u58ec\u916f\u6cbb\u7597\u540e\u5faa\u73af\u7f3a\u8840\u6240\u81f4\u7729\u6655\u2161b\u4e34\u5e8a\u8bd5\u9a8c<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20150585<\/span><\/p>\n<\/td>\n

\n

\u5df2\u5b8c\u6210<\/span><\/p>\n<\/td>\n

\n

\u5b89\u8111\u4e09\u9187\u6ce8\u5c04\u5242<\/span><\/p>\n<\/td>\n

\n

\u8111\u5352\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u5b89\u8111\u4e09\u9187\u6ce8\u5c04\u5242\u5728\u5065\u5eb7\u4eba\u4f53\u7684\u5b89\u5168\u6027\u8bc4\u4ef7<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20150440<\/span><\/p>\n<\/td>\n

\n

\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u94f6\u674f\u603b\u5185\u916f\u6ef4\u4e38<\/span><\/p>\n<\/td>\n

\n

\u7f3a\u8840\u6027\u8111\u5352\u4e2d\u6062\u590d\u671f<\/span><\/p>\n<\/td>\n

\n

\u94f6\u674f\u603b\u5185\u916f\u6ef4\u4e38\u2161a\u671f\u4e34\u5e8a\u7814\u7a76<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20150363<\/span><\/p>\n<\/td>\n

\n

\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u6d77\u4f26\u80f6\u56ca<\/span><\/p>\n<\/td>\n

\n

\u7f3a\u8840\u6027\u8111\u6897\u6b7b\u6062\u590d\u65e9\u671f\u3002<\/span><\/p>\n<\/td>\n

\n

\u4e00\u79cd\u6cbb\u7597\u4e2d\u98ce\u75c5\u7684\u8499\u836f\u65b0\u836f\u4e34\u5e8a\u7814\u7a76<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20140813<\/span><\/p>\n<\/td>\n

\n

\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u6ce8\u5c04\u7528\u7d22\u6cd5\u5730\u5c14<\/span><\/p>\n<\/td>\n

\n

\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u6ce8\u5c04\u7528\u7d22\u6cd5\u5730\u5c14\u6cbb\u7597\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d\u7684I\u671f\u4e34\u5e8a\u7814\u7a76<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20140805<\/span><\/p>\n<\/td>\n

\n

\u5df2\u5b8c\u6210<\/span><\/p>\n<\/td>\n

\n

\u6ce8\u5c04\u7528\u7532\u78fa\u9178\u80fa\u94f6\u5185\u916fB<\/span><\/p>\n<\/td>\n

\n

\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u6ce8\u5c04\u7528\u7532\u78fa\u9178\u80fa\u94f6\u5185\u916fB\u2160\u671f\u591a\u6b21\u4e34\u5e8a\u8bd5\u9a8c\u7814\u7a76\u65b9\u6848<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20140108<\/span><\/p>\n<\/td>\n

\n

\u5df2\u5b8c\u6210<\/span><\/p>\n<\/td>\n

\n

\u94f6\u674f\u5185\u916f\u6ce8\u5c04\u6db2<\/span><\/p>\n<\/td>\n

\n

\u7f3a\u8840\u6027\u8111\u5352\u4e2d\u6062\u590d\u671f\uff08\u75f0\u7600\u963b\u7edc\u8bc1\uff09<\/span><\/p>\n<\/td>\n

\n

\u94f6\u674f\u4e8c\u841c\u5185\u916f\u8461\u80fa\u6ce8\u5c04\u6db2\u5b89\u5168\u6027\u4e34\u5e8a\u7814\u7a76<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20140071<\/span><\/p>\n<\/td>\n

\n

\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u725b\u78fa\u9178\u6c2f\u5316\u94a0\u6ce8\u5c04\u6db2<\/span><\/p>\n<\/td>\n

\n

\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u725b\u78fa\u9178\u6cbb\u7597\u8111\u6897\u6b7b\u65e9\u671f\u60a3\u8005\u7684\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\u7684\u4e34\u5e8a\u7814\u7a76<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20132923<\/span><\/p>\n<\/td>\n

\n

\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u7f9f\u620a\u57fa\u82ef\u7532\u9178\u94be\u7247<\/span><\/p>\n<\/td>\n

\n

\u6cbb\u7597\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u7f9f\u620a\u57fa\u82ef\u7532\u9178\u94be\u7247 IIa\u671f\u4e34\u5e8a\u8bd5\u9a8c<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20132585<\/span><\/p>\n<\/td>\n

\n

\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u6ce8\u5c04\u7528\u4e39\u53c2\u591a\u915a\u9178<\/span><\/p>\n<\/td>\n

\n

\u7f3a\u8840\u6027\u8111\u5352\u4e2d\u6062\u590d\u671f<\/span><\/p>\n<\/td>\n

\n

\u6ce8\u5c04\u7528\u4e39\u53c2\u591a\u915a\u9178\u76ae\u80a4\u8fc7\u654f\u8bd5\u9a8c<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20132250<\/span><\/p>\n<\/td>\n

\n

\u8fdb\u884c\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u66ff\u683c\u745e\u6d1b\u7247<\/span><\/p>\n<\/td>\n

\n

\u5fc3\u808c\u6897\u6b7b\u75c5\u53f2\u7684\u60a3\u8005\u7684\u8840\u6813\u4e8b\u4ef6\u7684\u9884\u9632<\/span><\/p>\n<\/td>\n

\n

\u8bc4\u4ef7\u66ff\u683c\u745e\u6d1b\u5bf9\u6709\u5fc3\u808c\u6897\u6b7b\u75c5\u53f2\u7684\u60a3\u8005\u7684\u8840\u6813\u4e8b\u4ef6\u7684\u9884\u9632<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20132020<\/span><\/p>\n<\/td>\n

\n

\u5df2\u5b8c\u6210<\/span><\/p>\n<\/td>\n

\n

\u94f6\u674f\u5185\u916f\u6ce8\u5c04\u6db2<\/span><\/p>\n<\/td>\n

\n

\u7f3a\u8840\u6027\u8111\u5352\u4e2d\uff08\u6062\u590d\u671f\uff09\uff0c\u7600\u8840\u963b\u7edc\u8bc1\u3002<\/span><\/p>\n<\/td>\n

\n

\u94f6\u674f\u5185\u916f\u6ce8\u5c04\u6db2\u2163\u671f\u4e34\u5e8a\u7814\u7a76<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20131902<\/span><\/p>\n<\/td>\n

\n

\u5df2\u5b8c\u6210<\/span><\/p>\n<\/td>\n

\n

\u6e05\u8111\u5ba3\u7a8d\u6ef4\u4e38<\/span><\/p>\n<\/td>\n

\n

\u4e2d\u98ce\u75c5\u6062\u590d\u65e9\u671f<\/span><\/p>\n<\/td>\n

\n

\u6e05\u8111\u5ba3\u7a8d\u6ef4\u4e38\u6cbb\u7597\u4e2d\u98ce\u75c5\u6062\u590d\u65e9\u671f\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u7814\u7a76<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20131806<\/span><\/p>\n<\/td>\n

\n

\u5df2\u5b8c\u6210<\/span><\/p>\n<\/td>\n

\n

\u6ce8\u5c04\u7528\u7f9f\u620a\u57fa\u82ef\u7532\u9178\u94be<\/span><\/p>\n<\/td>\n

\n

\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u6ce8\u5c04\u7528PHPB\u5065\u5eb7\u4eba\u4f53\u591a\u6b21\u7ed9\u836f\u8010\u53d7\u6027\u53ca\u836f\u4ee3\u52a8\u529b\u5b66\u7814\u7a76<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n

\n

CTR20131788<\/span><\/p>\n<\/td>\n

\n

\u5df2\u5b8c\u6210<\/span><\/p>\n<\/td>\n

\n

\u6ce8\u5c04\u7528\u7f9f\u620a\u57fa\u82ef\u7532\u9178\u94be<\/span><\/p>\n<\/td>\n

\n

\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d<\/span><\/p>\n<\/td>\n

\n

\u6ce8\u5c04\u7528\u7f9f\u620a\u57fa\u82ef\u7532\u9178\u94be\u5065\u5eb7\u4eba\u4f53\u5355\u6b21\u7ed9\u836f\u836f\u4ee3\u52a8\u529b\u5b66\u8bd5\u9a8c<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n


<\/p>\n<\/section>\n

\u6ce8\uff1a\u4ee5\u4e0a\u5185\u5bb9\u4ec5\u4f9b\u53c2\u8003<\/span><\/p>\n

\u6b64\u524d<\/span>\u57282018\u5e7411<\/span>\u67081<\/span>\u65e5\uff0c\u5148\u58f0\u4e1c\u5143\uff0c\u4f9d\u8fbe\u62c9\u5949\u53f3\u65cb\u83b0\u9187\u6ce8\u5c04\u6db2\u4e0a\u5e02\u7533\u8bf7\u83b7\u5f97CDE<\/span>\u53d7\u7406\u516c\u793a\u3002<\/span><\/p>\n


<\/p>\n

\n
\n
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1.\u8bc4\u4ef7\u590d\u65b9\u4f9d\u8fbe\u62c9\u5949\u6ce8\u5c04\u6db2\u76f8\u6bd4\u4f9d\u8fbe\u62c9\u5949\u6ce8\u5c04\u6db2\u6cbb\u7597\u6025\u6027\u7f3a\u8840\u6027\u5352\u4e2d\u7684\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\u7684\u4e09\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u56fd\u5185\u5165\u7ec41200\u4eba; \u9996\u90fd\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u5317\u4eac\u5929\u575b\u533b\u9662\u738b\u62e5\u519b\u6559\u6388\u4e3a\u4e3b\u8981PI\u3002<\/span><\/p>\n

2.\u4e34\u5e8a\u4e3b\u8981\u7ec8\u70b9\uff1a<\/span><\/p>\n

\u6cbb\u7597\u7b2c90\u5929mRS\u8bc4\u5206\u22641\u5206\u7684\u60a3\u8005\u6bd4\u4f8b\uff08\u6539\u826f Rankin\u5352\u4e2d \u91cf\u8868\uff0cModified RankinScale\uff09\u3002<\/span><\/p>\n

3.2015-05-09\u56fd\u5185\u7b2c\u4e00\u4f8b\u60a3\u8005\u5165\u7ec4\uff1b<\/span><\/p>\n

2016-12-17\u56fd\u5185\u4e34\u5e8a\u8bd5\u9a8c\u7ed3\u675f\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


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\u53c2\u8003\uff1a<\/span><\/p>\n

NMPA\/CDE\uff1b<\/span><\/p>\n

\u836f\u878d\u6570\u636e\uff0cPharnex  Datamonitor;<\/span><\/p>\n

FDA\/EMA\uff1b<\/span><\/p>\n

\u76f8\u5173\u516c\u53f8\u516c\u5f00\u62ab\u9732;<\/span><\/p>\n

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\u5728\u6587\u540e\u7559\u8a00\uff0c\u5408\u9002\u7684\u53ef\u6dfb\u52a0Research\u533b\u836f\u4ebaDaniel\u5fae\u4fe1\u3002<\/p>\n


<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

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