{"id":60445,"date":"2018-11-15T01:00:00","date_gmt":"2018-12-07T02:56:55","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/12\/07\/32d4a067ab\/"},"modified":"2018-12-07T10:56:58","modified_gmt":"2018-12-07T02:56:58","slug":"32d4a067ab","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/60445\/","title":{"rendered":"MSD\u91cd\u78c5\uff0cPD-1\u63d0\u4ea4\u4e09\u5927\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u4e0a\u5e02\u7533\u8bf7"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">2018\u5e7411\u67089\u65e5\uff0c\u8bb0\u8005\u5728\u56fd\u9645\u80ba\u764c\u7814\u7a76\u5b66\u4f1a\u4e3e\u529e\u7684\u4e9a\u6d32\u80ba\u764c\u5927\u4f1a\u4e0a\u83b7\u6089\uff0c PD-1\u6291\u5236\u5242\u5e15\u535a\u5229\u73e0\u5355\u6297\uff08\u53ef\u745e\u8fbe\uff0c\u4fd7\u79f0\u201cK\u836f\u201d\uff09<\/span><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(230, 0, 18);box-sizing: border-box !important;word-wrap: break-word !important;\">\u5355\u836f\u4e00\u7ebf<\/span><\/strong><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">\u6cbb\u7597PD-L1\u8868\u8fbe\u9633\u6027[\u80bf\u7624\u6bd4\u4f8b\u8bc4\u5206\uff08TPS<span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\uff09<\/span>\u22651%]\u7684\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u7684\u4e0a\u5e02\u7533\u8bf7\uff0c\u5df2\u83b7CDE\u6b63\u5f0f\u53d7\u7406\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p><br  \/><\/p>\n<section class=\"\"    style=\"max-width: 100%;letter-spacing: 0.544px;line-height: 27.2px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\"    style=\"max-width: 100%;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(62, 62, 62);font-size: 16px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<section style=\"padding: 2px 10px;max-width: 100%;line-height: 25.6px;display: inline-block;vertical-align: top;border-radius: 15px 0px;color: rgb(255, 255, 255);background-color: rgb(230, 0, 18);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u4e00<\/span><\/strong><\/p>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(62, 62, 62);font-size: 16px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;line-height: 1.6;text-align: justify;box-sizing: border-box !important;word-wrap: break-word !important;\">\u83b7\u6279\u6709\u671b\u4e0e\u7f8e\u56fd\u540c\u6b65<\/span><\/strong><\/span><\/p>\n<\/section>\n<\/section>\n<p><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">\u8fd9\u662f\u7ee7\u4eca\u5e749\u670812\u65e5\u548c10\u670822\u65e5\u5e15\u535a\u5229\u73e0\u5355\u6297\u8054\u5408\u6807\u51c6\u5316\u7597\uff08\u57f9\u7f8e\u66f2\u585e\u548c\u987a\u94c2\/\u5361\u94c2\uff09<\/span><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(230, 0, 18);box-sizing: border-box !important;word-wrap: break-word !important;\">\u4e00\u7ebf<\/span><\/strong><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">\u6cbb\u7597\u975e\u9cde<span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">NSCLC<\/span>\uff0c\u4ee5\u53ca\u8054\u5408\u6807\u51c6\u5316\u7597\uff08\u5361\u94c2\u548c\u7d2b\u6749\u9187\u6216\u5361\u94c2\u548c\u767d\u86cb\u767d\u7d2b\u6749\u9187\uff09<\/span><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(230, 0, 18);box-sizing: border-box !important;word-wrap: break-word !important;\">\u4e00\u7ebf<\/span><\/strong><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">\u6cbb\u7597\u9cde\u72b6<span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">NSCLC<\/span>\u5206\u522b\u88abCDE\u6b63\u5f0f\u53d7\u7406\u4e4b\u540e\uff0c&#8221;K\u836f&#8221;\u7684\u7b2c\u4e09\u4e2a<\/span><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(230, 0, 18);box-sizing: border-box !important;word-wrap: break-word !important;\">\u4e00\u7ebf<\/span><\/strong><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">\u6cbb\u7597<span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">NSCLC<\/span>\u7684\u4e0a\u5e02\u7533\u8bf7\u83b7\u5f97CDE\u53d7\u7406\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">CDE\u5728\u5982\u6b64\u77ed\u7684\u65f6\u95f4\u5185\uff0c\u8fde\u7eed\u53d7\u7406\u5e15\u535a\u5229\u73e0\u5355\u6297\u7684\u4e09\u4e2a\u65b0\u9002\u5e94\u8bc1\u7684\u7533\u8bf7\u662f\u6e90\u4e8e\u5e15\u535a\u5229\u73e0\u5355\u6297\u5728\u4eca\u5e748\u6708\u4efd\u4f5c\u4e3a\u552f\u4e00\u4e00\u4e2aPD-1\u5355\u6297\u88ab\u7eb3\u5165CDE\u516c\u5e03\u7684\u5883\u5916\u5df2\u4e0a\u5e02\u7684\u4e34\u5e8a\u6025\u9700\u836f\u54c1\u540d\u5355<span style=\"max-width: 100%;font-size: 12px;box-sizing: border-box !important;word-wrap: break-word !important;\"><sup style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5fae\u8f6f\u96c5\u9ed1;vertical-align: super;box-sizing: border-box !important;word-wrap: break-word !important;\">[1]<\/span><\/sup><\/span>\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">\u8be5\u540d\u5355\u91cd\u70b9\u8003\u8651\u8fd1\u5e74\u6765\u7f8e\u56fd\u3001\u6b27\u76df\u6216\u65e5\u672c\u6279\u51c6\u4e0a\u5e02\uff0c\u800c\u6211\u56fd\u5c1a\u672a\u4e0a\u5e02\u7684\u7528\u4e8e\u7f55\u89c1\u75c5\u6cbb\u7597\u7684\u65b0\u836f\uff1b\u4ee5\u53ca\u7528\u4e8e\u9632\u6cbb\u4e25\u91cd\u5371\u53ca\u751f\u547d\u6216\u4e25\u91cd\u5f71\u54cd\u751f\u6d3b\u8d28\u91cf\u7684\u75be\u75c5\uff0c\u4e14\u5c1a\u65e0\u6709\u6548\u6cbb\u7597\u624b\u6bb5\u6216<\/span><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">\u5177\u6709\u660e\u663e\u4e34\u5e8a\u4f18\u52bf\u7684\u65b0\u836f\u3002\u5bf9\u4e8e\u8fd9\u4e9b\u836f\u54c1\u7684\u4e0a\u5e02\u7533\u8bf7\uff0c&nbsp;\u56fd\u5bb6\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u603b\u5c40\u5c06\u6309\u7167\u4f18\u5148\u5ba1\u8bc4\u5ba1\u6279\u7a0b\u5e8f\uff0c\u52a0\u5feb\u5ba1\u8bc4\u5ba1\u6279\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">KEYNOTE-042\u4e2d\u56fd\u7814\u7a76\u7275\u5934\u4eba\u3001\u5e7f\u4e1c\u7701\u80ba\u764c\u7814\u7a76\u6240\u540d\u8a89\u6240\u957f\u3001\u5e7f\u4e1c\u7701\u4eba\u6c11\u533b\u9662\u7ec8\u8eab\u4e3b\u4efb\u5434\u4e00\u9f99\u6559\u6388<\/span><\/strong><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">\u8868\u793a\uff1a<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p><br  \/><\/p>\n<section class=\"\"    style=\"max-width: 100%;letter-spacing: 0.544px;line-height: 27.2px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\"    style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\"    style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;padding: 15px 20px 15px 45px;max-width: 100%;font-size: 14px;line-height: 22.39px;outline: 0px;border-width: 0px;border-style: initial;border-color: currentcolor;color: rgb(62, 62, 62);vertical-align: baseline;background-image: url('http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/9-1544151418.jpeg');background-color: rgb(241, 241, 241);background-position: 1% 5px;background-repeat: no-repeat;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">\u5e15\u535a\u5229\u73e0\u5355\u6297\u80ba\u764c\u9002\u5e94\u8bc1\u4e00\u65e6\u5728\u56fd\u5185\u83b7\u6279\uff0c\u5c06\u52a0\u901f\u63a8\u8fdb\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u5728\u56fd\u5185\u7684\u4e00\u7ebf\u4e34\u5e8a\u5e94\u7528\uff0c\u8fd9\u610f\u5473\u7740\u665a\u671fNSCLC\u60a3\u8005\uff0c\u65e0\u8bba\u662f\u521d\u6cbb\u60a3\u8005\uff0c\u8fd8\u662f\u6b63\u5728\u63a5\u53d7\u6807\u51c6\u5316\u7597\u7684\u60a3\u8005\uff0c\u65e0\u8bba\u662f\u9cde\u764c\u8fd8\u662f\u975e\u9cde\u764cNSCLC\u60a3\u8005\uff0c\u90fd\u53ef\u4ee5\u5c3d\u65e9\u5f00\u59cb\u80bf\u7624\u514d\u75ab\u6cbb\u7597\uff0c\u4ece\u800c\u5c3d\u5feb\u4ece\u6cbb\u7597\u4e2d\u83b7\u76ca\uff0c\u800c\u4e14\u8d8a\u65e9\u5f00\u59cb\u514d\u75ab\u6cbb\u7597\uff0c\u6548\u679c\u8d8a\u597d\uff01<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/span><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;text-align: center;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"      style=\"color: rgb(62, 62, 62);box-sizing: border-box !important;word-wrap: break-word !important;width: 440.047px !important;visibility: visible !important;\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/1-1544151416.jpg\" alt=\"MSD\u91cd\u78c5\uff0cPD-1\u63d0\u4ea4\u4e09\u5927\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u4e0a\u5e02\u7533\u8bf7\" title=\"MSD\u91cd\u78c5\uff0cPD-1\u63d0\u4ea4\u4e09\u5927\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u4e0a\u5e02\u7533\u8bf7\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;text-align: center;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(136, 136, 136);font-size: 14px;text-align: justify;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5434\u4e00\u9f99\u6559\u6388<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6b64\u6b21PD-1\u5355\u6297\u5355\u836f\u4e00\u7ebf\u6cbb\u7597\u7684\u9002\u5e94\u8bc1\u83b7\u5f97CDE\u53d7\u7406\u610f\u5473\u7740\uff0c\u90a3\u4e9b\u4e0d\u9002<span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5408<\/span>\u5316\u7597\u6216\u8005\u65e0\u6cd5\u8010\u53d7\u5316\u7597\u7684\u4e2d\u56fdNSCLC\u60a3\u8005\u4e5f\u6709\u671b\u63a5\u53d7PD-1\u5355\u6297\u4e00\u7ebf\u6cbb\u7597\uff0c\u4ece\u800c\u83b7\u5f97\u66f4\u957f\u7684\u603b\u751f\u5b58\u671f\u3002<\/span><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">\u7f8e\u56fdFDA \u4e5f\u4e8e\u4eca\u5e749\u670812\u65e5\u540c\u610f\u52a0\u901f\u5ba1\u8bc4\u5ba1\u6279\u201cK\u836f\u201c\u4e00\u7ebf\u6cbb\u7597PD-L1\u8868\u8fbe\u22651%\u7684NSCLC\uff0c\u5e76\u627f\u8bfa\u6700\u665a\u4e8e2019\u5e741\u670811\u65e5\u4e4b\u524d\u7ed9\u51fa\u6700\u7ec8\u5ba1\u8bc4\u610f\u89c1\u3002\u6709\u8da3\u7684\u662f\uff0c\u7f8e\u56fdFDA\u521a\u4e8e\u4eca\u5e748\u670828\u65e5\u548c10\u670830\u65e5\u6b63\u5f0f\u6279\u51c6&#8221;K\u836f\u201c\u8054\u5408\u6807\u51c6\u5316\u7597\u4e00\u7ebf\u6cbb\u7597\u975e\u9cdeNSCLC\u548c\u9cde\u72b6NSCLC\u3002\u5982\u679c\u8fd9\u4e24\u4e2a\u9002\u5e94\u8bc1\u5728\u4e2d\u56fd\u4e8e\u4eca\u5e74\u5e74\u5e95\u6216\u660e\u5e74\u5e74\u521d\u83b7\u6279\uff0c\u90a3\u4e2d\u56fd\u83b7\u6279\u65f6\u95f4\u6bd4\u7f8e\u56fd\u53ea\u665a\u4e862-3\u4e2a\u6708\u3002\u800c\u6b64\u6b21CDE\u5feb\u901f\u53d7\u7406&#8221;K\u836f\u201d\u5355\u836f\u4e00\u7ebf\u6cbb\u7597NSCLC\u6709\u671b\u4f7f\u8be5\u9002\u5e94\u8bc1\u7684\u83b7\u6279\u4e0e\u7f8e\u56fd\u57fa\u672c\u540c\u6b65\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p><br  \/><\/p>\n<section class=\"\"    style=\"max-width: 100%;letter-spacing: 0.544px;line-height: 27.2px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\"    style=\"max-width: 100%;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(62, 62, 62);font-size: 16px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<section style=\"padding: 2px 10px;max-width: 100%;line-height: 25.6px;display: inline-block;vertical-align: top;border-radius: 15px 0px;color: rgb(255, 255, 255);background-color: rgb(230, 0, 18);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u4e8c<\/span><\/strong><\/p>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(62, 62, 62);font-size: 16px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;line-height: 1.6;text-align: justify;box-sizing: border-box !important;word-wrap: break-word !important;\">PD-L1\u4f34\u968f\u8bca\u65ad\u4e0e\u836f\u7269\u9996\u6b21\u540c\u6b65\u5ba1\u6279<\/span><\/strong><\/span><\/p>\n<\/section>\n<\/section>\n<p><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">&nbsp;<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">\u6b64\u6b21CDE\u53d7\u7406&#8221;K\u836f\u201d\u5355\u836f\u4e00\u7ebf\u6cbb\u7597\u4e0a\u5e02\u7533\u8bf7\uff0c\u662f\u57fa\u4e8e\u4e00\u9879\u4eca\u5e74\u5728\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\u5e74\u4f1a\u4e0a\u516c\u5e03\u7684\u4e00\u9879\u5927\u578b\u56fd\u9645\u591a\u4e2d\u5fc3\uff0c\u968f\u673a\u3001\u5f00\u653e\u6807\u7b7eIII\u671f\u4e34\u5e8a\u7814\u7a76\u7684\u7ed3\uff08<strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">KEYNOTE-042<\/strong>\uff09\u3002\u8be5\u7814\u7a76\u5bf9PD-L1\u8868\u8fbe\u4e0d\u540c\u7684\u4eba\u7fa4\u4f9d\u6b21\u5206\u5c42\u505a\u4e86<span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u603b\u751f\u5b58\uff08OS\uff09<\/span>\u7684\u8bc4\u4f30\u5206\u6790\uff0c\u53d1\u73b0<strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">TPS\u226550%\u7684\u4eba\u7fa4\u7684\u6b7b\u4ea1\u98ce\u9669\u964d\u4f4e\u4e8631%\uff1b\u6240\u6709TPS\u22651%\u7684\u4eba\u7fa4\u7684\u6b7b\u4ea1\u98ce\u9669\u964d\u4f4e\u4e8619%<\/strong>\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">&nbsp;<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 27.2px;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"       style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: 677px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/2-1544151416.jpg\" alt=\"MSD\u91cd\u78c5\uff0cPD-1\u63d0\u4ea4\u4e09\u5927\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u4e0a\u5e02\u7533\u8bf7\" title=\"MSD\u91cd\u78c5\uff0cPD-1\u63d0\u4ea4\u4e09\u5927\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u4e0a\u5e02\u7533\u8bf7\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 27.2px;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 27.2px;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"       style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: 677px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/5-1544151417.jpg\" alt=\"MSD\u91cd\u78c5\uff0cPD-1\u63d0\u4ea4\u4e09\u5927\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u4e0a\u5e02\u7533\u8bf7\" title=\"MSD\u91cd\u78c5\uff0cPD-1\u63d0\u4ea4\u4e09\u5927\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u4e0a\u5e02\u7533\u8bf7\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">&nbsp;<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">\u7f8e\u56fdFDA\u4e8e2016\u5e74\u6279\u51c6\u5e15\u535a\u5229\u73e0\u5355\u6297\u5355\u836f\u4e00\u7ebf\u6cbb\u7597PD-L1\u9ad8\u8868\u8fbe\uff08TPS\u226550%<span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\uff09<\/span>\u7684\u4e4b\u524d\u672a\u66fe\u63a5\u53d7\u8fc7\u7cfb\u7edf\u5316\u7597\u7684\u665a\u671f<span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">NSCLC\u60a3\u8005<\/span>\uff0c\u5e76\u8981\u6c42\u60a3\u8005\u5728\u6cbb\u7597\u524d\u5fc5\u987b\u4f7f\u7528\u4e39\u9ea6Dako\u516c\u53f8\u751f\u4ea7\u7684\u68c0\u6d4b\u8bd5\u5242\u76d2 22C3 \u68c0\u6d4bPD-L1\uff0c\u5e76\u4ee5\u68c0\u6d4b\u7ed3\u679c\u6307\u5bfc&#8221;K\u836f\u201c\u6cbb\u7597\u3002<\/span><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">22C3\u8bd5\u5242\u76d2\u4e5f\u56e0\u6b64\u6210\u4e3a\u7b2c\u4e00\u4e2a\uff0c\u4e5f\u662f\u76ee\u524d\u552f\u4e00\u88ab\u7f8e\u56fdFDA\u6279\u51c6\u7684PD-1\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u6cbb\u7597\u7684\u4f34\u968f\u8bca\u65ad\u65b9\u6cd5\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u636e\u6089\uff0cDAKO\u516c\u53f8\u5df2\u9012\u4ea4<\/span><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">22C3\u5728\u56fd\u5185\u7684\u4e0a\u5e02\u7533\u8bf7\uff0c\u5e76\u83b7\u5f97\u4e86\u533b\u7597\u5668\u68b0\u6280\u672f\u5ba1\u8bc4\u4e2d\u5fc3\u62df\u5b9a\u4e88\u4ee5\u4f18\u5148\u5ba1\u8bc4\u8d44\u683c\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 27.2px;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"       style=\"box-sizing: border-box !important;word-wrap: break-word !important;width: 677px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/8-1544151417.jpeg\" alt=\"MSD\u91cd\u78c5\uff0cPD-1\u63d0\u4ea4\u4e09\u5927\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u4e0a\u5e02\u7533\u8bf7\" title=\"MSD\u91cd\u78c5\uff0cPD-1\u63d0\u4ea4\u4e09\u5927\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u4e0a\u5e02\u7533\u8bf7\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">&nbsp;<\/span><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">\u56e0\u6b64\uff0c\u5f88\u53ef\u80fd\u4e0e\u201cK\u836f\u201d\u5355\u836f\u4e00\u7ebf\u6cbb\u7597PD-L1\u22651%\u7684NSCLC\u7684\u4e0a\u5e02\u7533\u8bf7\u540c\u6b65\u83b7\u6279\uff0c\u5e76\u4f5c\u4e3a\u201cK\u836f\u201d\u4e34\u5e8a\u4f7f\u7528\u7684\u4f34\u968f\u8bca\u65ad\uff0c\u4ece\u800c\u5f00\u521b\u4e2d\u56fd\u4f34\u968f\u8bca\u65ad\u8bd5\u5242\u4e0e\u836f\u7269\u540c\u6b65\u83b7\u6279\u7684&#8221;\u5148\u6cb3\u201c\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">\u5434\u4e00\u9f99\u6559\u6388<\/span><\/strong><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">\u8ba4\u4e3a\uff0c\u5982\u679c22C3\u6297\u4f53PD-L1\u68c0\u6d4b\u4f5c\u4e3a\u4f34\u968f\u8bca\u65ad\u4e0e\u5e15\u535a\u5229\u73e0\u5355\u6297\u5355\u836f\u4e00\u7ebf\u6cbb\u7597\u540c\u6b65\u83b7\u6279\uff0c\u8fd9\u5c06\u662f\u56fd\u5185\u80ba\u764c\u6cbb\u7597\u53f2\u4e0a\u7684\u4e00\u4e2a\u91cc\u7a0b\u7891\uff01\u6211\u4eec\u5728\u5206\u5b50\u9776\u5411\u6cbb\u7597\u4e0a\u7684\u7ecf\u9a8c\u544a\u8bc9\u6211\u4eec\uff0c\u5bf9\u4e8e\u9a71\u52a8\u57fa\u56e0\u7684\u7cbe\u51c6\u5224\u65ad\u53ef\u4ee5\u6307\u5bfc\u6cbb\u7597\u65b9\u6848\u7684\u5236\u8ba2\uff0c\u56e0\u6b64\uff0c\u7cbe\u51c6\u8bca\u65ad\u662f\u5b9e\u65bd\u9776\u5411\u6cbb\u7597\u7684\u524d\u63d0\uff1b\u800c\u514d\u75ab\u5355\u836f\u6cbb\u7597\u5e76\u975e\u5bf9\u6240\u6709NSCLC\u60a3\u8005\u6709\u6548\uff0c\u56e0\u6b64\uff0c\u7cbe\u51c6\u8bca\u65ad\u540c\u6837\u4e0d\u53ef\u6216\u7f3a\u3002PD-L1\u662f\u76ee\u524d\u6700\u6210\u719f\u7684\u514d\u75ab\u6cbb\u7597\u751f\u7269\u6807\u5fd7\u7269\uff0c22C3\u8bd5\u5242\u76d2\u4f5c\u4e3a\u4f34\u968f\u8bca\u65ad\u540c\u6b65\u83b7\u6279\u5c06\u63a8\u52a8\u6211\u56fd\u7684\u7cbe\u51c6\u514d\u75ab\u6cbb\u7597\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p><br  \/><\/p>\n<section class=\"\"    style=\"max-width: 100%;letter-spacing: 0.544px;line-height: 27.2px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\"    style=\"max-width: 100%;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(62, 62, 62);font-size: 16px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<section style=\"padding: 2px 10px;max-width: 100%;line-height: 25.6px;display: inline-block;vertical-align: top;border-radius: 15px 0px;color: rgb(255, 255, 255);background-color: rgb(230, 0, 18);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u4e09<\/span><\/strong><\/p>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(62, 62, 62);font-size: 16px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;line-height: 1.6;text-align: justify;box-sizing: border-box !important;word-wrap: break-word !important;\">&nbsp;\u201cK\u836f\u201d\u63a8\u52a8PD-1\u5355\u6297\u8fdb\u5165\u6cdb\u80bf\u7624\u6cbb\u7597\u7684\u201c\u4e00\u7ebf\u5c97\u4f4d\u201d<\/span><\/strong><\/span><\/p>\n<\/section>\n<\/section>\n<p><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">&nbsp;<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">\u5728\u7f8e\u56fd\uff0c\u5728\u665a\u671f<span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">NSCLC<\/span>\u3001\u6076\u6027\u9ed1\u8272\u7d20\u7624\u3001\u5c3f\u8def\u4e0a\u76ae\u7ec6\u80de\u764c\u6cbb\u7597\u4e0a\uff0c\u5e15\u535a\u5229\u73e0\u5355\u6297\u5df2\u7ecf\u53d6\u4ee3\u4f20\u7edf\u6cbb\u7597\u65b9\u6848\uff0c\u6210\u4e3a\u6807\u51c6\u4e00\u7ebf\u6cbb\u7597\u65b9\u6848\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">\u4eca\u5e7410\u670822\u65e5\uff0c\u5728\u6b27\u6d32\u80bf\u7624\u5b66\u4f1a\u5e74\u4f1a\u4e0a\u516c\u5e03\u7684KEYNOTE-048\u5927\u578bIII\u671f\u4e34\u5e8a\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c \u5934\u9888\u90e8\u9cde\u764c\u7684\u6cbb\u7597\u4e0a\uff0c\u76f8\u6bd4\u73b0\u6709\u7684\u4e00\u7ebf\u8054\u5408\u6cbb\u7597\u65b9\u6848\uff0c\u201cK\u836f\u201d\u5355\u836f\u6216\u8005\u662f\u8054\u5408\u5316\u7597\u80fd\u4e3a\u60a3\u8005\u5e26\u6765\u66f4\u663e\u8457\u7684\u751f\u5b58\u83b7\u76ca\uff1b\u56e0\u6b64\uff0c\u201cK\u836f\u201d\u6709\u671b\u5728\u5934\u9888\u90e8\u9cde\u764c\u6cbb\u7597\u4e0a\uff0c\u628aPD-1\u5355\u6297\u518d\u6b21\u63a8\u4e0a\u201c\u4e00\u7ebf\u5c97\u4f4d\u201d\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p><br  \/><\/p>\n<section class=\"\"    style=\"max-width: 100%;letter-spacing: 0.544px;line-height: 27.2px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\"    style=\"max-width: 100%;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(62, 62, 62);font-size: 16px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<section style=\"padding: 2px 10px;max-width: 100%;line-height: 25.6px;display: inline-block;vertical-align: top;border-radius: 15px 0px;color: rgb(255, 255, 255);background-color: rgb(230, 0, 18);box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u56db<\/span><\/strong><\/p>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(62, 62, 62);font-size: 16px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;line-height: 1.6;text-align: justify;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5f97\u201c\u4e00\u7ebf\u201d\u8005\u5f97\u5929\u4e0b<\/span><\/strong><\/span><\/p>\n<\/section>\n<\/section>\n<p><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">&nbsp;<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">2016\u5e74\uff0c\u201cK\u836f\u201d\u5728\u7f8e\u56fd\u83b7\u6279\u4e00\u7ebf\u5355\u836f\u6cbb\u7597PD-L1\u9ad8\u8868\u8fbe\uff08TPS\u226550%\uff09 \u7684NSCLC\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">2018\u5e748\u6708\uff0cFDA\u6279\u51c6\u201cK\u836f\u201d\u8054\u5408\u57f9\u7f8e\u66f2\u585e\u548c\u94c2\u7c7b\u5316\u7597\u7528\u4e8e\u65e0EGFR\u6216ALK\u57fa\u56e0\u7a81\u53d8\u7684\u8f6c\u79fb\u6027\u975e\u9cde<span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">NSCLC<\/span>\u60a3\u8005\u7684\u4e00\u7ebf\u6cbb\u7597\uff0c\u8fd9\u9879\u6279\u51c6\u662fPD-1\u5355\u6297\u7b2c\u4e00\u6b21\u83b7\u5f97\u6279\u51c6\u4f5c\u4e3a\u4e00\u7ebf\u7597\u6cd5\u6cbb\u7597\u975e\u9cde\u72b6NSCLC\uff0c\u800c\u4e14\u4e0d\u9700\u8003\u8651\u80bf\u7624\u7684PD-L1\u8868\u8fbe\u6c34\u5e73\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">2018\u5e7410\u670830\u65e5\uff0c\u7f8e\u56fdFDA\u6279\u51c6\u201cK\u836f\u201d\u4e0e\u5361\u94c2\u548c\u7d2b\u6749\u9187\u8054\u7528\uff0c\u4f5c\u4e3a\u4e00\u7ebf\u7597\u6cd5\u6cbb\u7597\u8f6c\u79fb\u6027\u9cde\u72b6<span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">NSCLC<\/span>\u3002\u8fd9\u9879\u6279\u51c6\u662f\u6297PD-1\u7597\u6cd5\u7b2c\u4e00\u6b21\u83b7\u5f97\u6279\u51c6\u4f5c\u4e3a\u4e00\u7ebf\u7597\u6cd5\u6cbb\u7597\u9cde\u72b6NSCLC\uff0c\u800c\u4e14\u4e0d\u9700\u8003\u8651\u80bf\u7624\u7684PD-L1\u8868\u8fbe\u6c34\u5e73\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">\u5728\u6240\u6709\u7684PD-1\u5355\u6297\u4e2d\uff0c \u201cK\u836f\u201d\u662f\u76ee\u524d<\/span><span style=\"max-width: 100%;font-size: 15px;color: rgb(230, 0, 18);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u552f\u4e00<\/strong><\/span><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">\u4e00\u4e2a\u663e\u793a\u5728\u5355\u836f\u4e00\u7ebf\u6cbb\u7597\uff0c\u6216\u8054\u5408\u5316\u7597\u4e00\u7ebf\u6cbb\u7597NSCLC\u65f6\u80fd\u5e26\u6765OS\u83b7\u76ca\uff0c\u964d\u4f4e\u6b7b\u4ea1\u98ce\u9669\u7684PD-1\u6291\u5236\u5242<\/span><span style=\"max-width: 100%;font-size: 12px;box-sizing: border-box !important;word-wrap: break-word !important;\"><sup style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5fae\u8f6f\u96c5\u9ed1;vertical-align: super;box-sizing: border-box !important;word-wrap: break-word !important;\">[2-4]<\/span><\/sup><\/span><span style=\"max-width: 100%;font-size: 15px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 27.2px;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;text-align: center;line-height: 1.5em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;color: rgb(136, 136, 136);box-sizing: border-box !important;word-wrap: break-word !important;\">\u70b9\u5f00\u770b\u5927\u56fe<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">&nbsp;<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: normal;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(136, 136, 136);font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u53c2\u8003\u6587\u732e<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: normal;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;color: rgb(136, 136, 136);box-sizing: border-box !important;word-wrap: break-word !important;\">[1]http:\/\/www.cde.org.cn\/news.do?method=viewInfoCommon&amp;id=314651<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: normal;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;color: rgb(136, 136, 136);box-sizing: border-box !important;word-wrap: break-word !important;\">[2]Giberto Lopes et al., Plenary Presentation LBA 4 ASCO 2018<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: normal;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;color: rgb(136, 136, 136);box-sizing: border-box !important;word-wrap: break-word !important;\">[3]Luiz G. Paz-Ares et al., Oral Presentation ASCO 2018<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: normal;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;color: rgb(136, 136, 136);box-sizing: border-box !important;word-wrap: break-word !important;\">[4]Gandhi et al., Pembrolizumab plus chemotherapy in metastatic non-small-cell lung cancer, May 31,2018 N Engl J Med 2018; 378:2078-2092&nbsp;<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5fae\u8f6f\u96c5\u9ed1;letter-spacing: 0.544px;white-space: pre-wrap;font-size: 14px;color: rgb(127, 127, 127);box-sizing: border-box !important;word-wrap: break-word !important;\">\u7248\u6743\u58f0\u660e\uff1a\u672c\u6587\u8f6c\u81ea<\/span><span style=\"max-width: 100%;font-family: \u5fae\u8f6f\u96c5\u9ed1;letter-spacing: 0.544px;white-space: pre-wrap;font-size: 14px;color: rgb(127, 127, 127);box-sizing: border-box !important;word-wrap: break-word !important;\">\u533b\u5b66\u754c\u80bf\u7624\u9891\u9053<\/span><span style=\"max-width: 100%;font-family: \u5fae\u8f6f\u96c5\u9ed1;letter-spacing: 0.544px;white-space: pre-wrap;font-size: 14px;color: rgb(127, 127, 127);box-sizing: border-box !important;word-wrap: break-word !important;\">\uff0c<span style=\"max-width: 100%;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, Arial, sans-serif;font-size: 0px;letter-spacing: 0.544px;line-height: 20px;box-sizing: border-box !important;word-wrap: break-word !important;\">&nbsp;<\/span>\u5982\u4e0d\u5e0c\u671b\u88ab\u8f6c\u8f7d\u7684\u5a92\u4f53\u6216\u4e2a\u4eba\u53ef\u4e0e\u6211\u4eec\u8054\u7cfb\uff0c\u6211\u4eec\u5c06\u7acb\u5373\u5220\u9664<\/span><\/p>\n<p><br  \/><\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>2018\u5e7411\u67089\u65e5\uff0c\u8bb0\u8005\u5728\u56fd\u9645\u80ba\u764c\u7814\u7a76\u5b66\u4f1a\u4e3e\u529e\u7684\u4e9a\u6d32\u80ba\u764c\u5927\u4f1a\u4e0a\u83b7\u6089\uff0c PD-1\u6291\u5236\u5242\u5e15\u535a\u5229\u73e0\u5355\u6297\uff08\u53ef\u745e\u8fbe\uff0c\u4fd7 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":60446,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/60445"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=60445"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/60445\/revisions"}],"predecessor-version":[{"id":60452,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/60445\/revisions\/60452"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/60446"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=60445"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=60445"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=60445"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}