{"id":60966,"date":"2018-10-29T01:00:00","date_gmt":"2018-12-07T03:03:19","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/12\/07\/8dbf3e928d\/"},"modified":"2018-12-07T11:03:23","modified_gmt":"2018-12-07T03:03:23","slug":"8dbf3e928d","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/60966\/","title":{"rendered":"\u6bcf\u5468\u836f\u8baf\uff082018\u5e74\u7b2c37\u671f\uff09"},"content":{"rendered":"
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\u56fd\u5916\u836f\u7269\u7814\u53d1\u52a8\u6001<\/span><\/section>\n<\/section>\n
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1\u3001Clovis Oncology\u516c\u53f8\u57282018\u5e74\u6b27\u6d32\u80bf\u7624\u5185\u79d1\u5b66\u4f1a\u5e74\u4f1a\u4e0a\u53d1\u5e03\u4e86\u8be5\u516c\u53f8\u7814\u53d1\u7684Rubraca\uff08rucaparib\uff09\uff0c\u5728\u6cbb\u7597\u643a\u5e26BRCA1\/2\u57fa\u56e0\u7a81\u53d8\u7684\u524d\u5217\u817a\u764c\u60a3\u8005\u76842\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0c\u83b7\u5f97\u7684\u79ef\u6781\u7ed3\u679c\u3002\u8bd5\u9a8c\u7ed3\u679c\u8868\u660e\uff0c\u63a5\u53d7Rubraca\u6cbb\u7597\u7684\u60a3\u8005\u7684\u786e\u8ba4\u5ba2\u89c2\u7f13\u89e3\u7387\uff08ORR\uff09\u8fbe\u523044%\u3002\u57fa\u4e8e\u8fd9\u9879\u8bd5\u9a8c\u7684\u521d\u6b65\u7ed3\u679c\uff0c\u7f8e\u56fdFDA\u572810\u67082\u65e5\u6388\u4e88Rubraca\u6cbb\u7597\u8f6c\u79fb\u6027\u53bb\u52bf\u62b5\u6297\u6027\u524d\u5217\u817a\u764c\uff08mCRPC\uff09\u7684\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\u3002<\/span>
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2\u3001\u8bfa\u534e\uff08Novartis\uff09\u65e5\u524d\u4e8e\u6b27\u6d32\u80bf\u7624\u5185\u79d1\u5b66\u4f1a\uff08ESMO\uff092018\u5e74\u5927\u4f1a\u4e0a\u5ba3\u5e03\u4e86\u5176\u91cd\u78c5\u65b0\u7597\u6cd5Lutathera\uff08lutetium Lu 177 dotatate*\uff09\uff0c\u5728\u6cbb\u7597\u4e2d\u80a0\u795e\u7ecf\u5185\u5206\u6ccc\u80bf\u7624\uff08NETs\uff09\u60a3\u8005\u76843\u671f\u4e34\u5e8a\u8bd5\u9a8cNETTER-1\u4e2d\u83b7\u5f97\u7684\u79ef\u6781\u5206\u6790\u7ed3\u679c\u3002\u672c\u6b21\u516c\u5e03\u7684\u6570\u636e\u663e\u793a\uff0c\u4e0e\u5355\u72ec\u4f7f\u7528octreotide LAR\u76f8\u6bd4\uff0cLutathera\u7597\u6cd5\u5927\u5e45\u5ea6\u6539\u5584\u4e86\u4e2d\u80a0NET\u60a3\u8005\u7684\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\u3002\u8fd9\u4e00\u6539\u5584\u4e0d\u53d7\u5230\u60a3\u8005\u809d\u810f\u80bf\u7624\u8d1f\u62c5\uff08LTB\uff09\uff0c\u809d\u810f\u4e2d\u7684\u78b1\u6027\u78f7\u9178\u9176\uff08ALP\uff09\u6c34\u5e73\u6216\u80bf\u7624\u76f4\u5f84\u5927\u5c0f\u7684\u5f71\u54cd\u3002<\/span><\/p>\n

3\u3001\u7f8e\u56fd\u751f\u7269\u6280\u672f\u5de8\u5934\u827e\u4f2f\u7ef4\u8fd1\u65e5\u5ba3\u5e03\uff0c\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40\uff08FDA\uff09\u5df2\u6279\u51c6\u6269\u5927Humira\uff08\u4fee\u7f8e\u4e50\uff0c\u901a\u7528\u540d\uff1aadalimumab\uff0c\u963f\u8fbe\u6728\u5355\u6297\uff09\u6cbb\u7597\u975e\u611f\u67d3\u6027\u8461\u8404\u819c\u708e\u7684\u9002\u7528\u4eba\u7fa4\uff0c\u7eb3\u51652\u5c81\u53ca\u4ee5\u4e0a\u513f\u7ae5\u60a3\u8005\u3002<\/span><\/p>\n

4\u300110\u670818\u65e5\uff0c\u7f8e\u56fd\u9ed8\u6c99\u4e1c\u5236\u836f\u516c\u5e03\u79f0\uff0cKEYTRUDA\uff08pembrolizumab\uff09\u8054\u5408\u8f89\u745eInlyta\uff08axitinib\uff0c\u963f\u897f\u66ff\u5c3c\uff09\u7528\u4e8e\u665a\u671f\u6216\u8f6c\u79fb\u6027\u80be\u7ec6\u80de\u764c\uff08RCC\uff09\u6cbb\u7597\u7684\u5173\u952e3\u671f\u7814\u7a76KEYNOTE-426\u8fbe\u5230\u4e86\u603b\u751f\u5b58\u671f\uff08OS\uff09\u53ca\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\u7684\u4e3b\u8981\u7814\u7a76\u7ec8\u70b9\u3002<\/span><\/p>\n

5\u3001\u65e5\u672c\u836f\u4f01\u7b2c\u4e00\u4e09\u5171\uff08Daiichi Sankyo\uff09\u5236\u836f\u8fd1\u65e5\u5ba3\u5e03\uff0c\u5df2\u5411\u65e5\u672c\u536b\u751f\u52b3\u52a8\u798f\u5229\u90e8\uff08MHLW\uff09\u63d0\u4ea4\u4e86\u9776\u5411\u6297\u764c\u836fquizartinib\u6cbb\u7597\u590d\u53d1\u6027\/\u96be\u6cbb\u6027FLT3-ITD\u6025\u6027\u9ad3\u6027\u767d\u8840\u75c5\uff08AML\uff09\u6210\u4eba\u60a3\u8005\u7684\u65b0\u836f\u7533\u8bf7\uff08NDA\uff09\u3002\u6b64\u6b21\u7533\u8bf7\uff0c\u662f\u57fa\u4e8e\u5728\u7f8e\u56fd\u3001\u6b27\u76df\u3001\u4e9a\u6d32\uff08\u4e0d\u5305\u62ec\u65e5\u672c\uff09\u5f00\u5c55\u7684\u5173\u952e\u6027\u968f\u673aIII\u671f\u4e34\u5e8a\u7814\u7a76QuANTUM-R\u7684\u6570\u636e\u3001\u4ee5\u53ca\u5728\u65e5\u672c\u5f00\u5c55\u7684\u6cbb\u7597\u590d\u53d1\u6027\/\u96be\u6cbb\u6027FLT3-ITD AML\u6210\u4eba\u60a3\u8005\u7684\u5f00\u653e\u6807\u7b7e\u5355\u7ec4II\u671f\u7814\u7a76\u7684\u6570\u636e\u3002\u503c\u5f97\u4e00\u63d0\u7684\u662f\uff0cquizartinib\u662f\u6cbb\u7597\u590d\u53d1\u6027\/\u96be\u6cbb\u6027FLT3-ITD AML\u968f\u673aIII\u671f\u7814\u7a76\u4e2d\u53e3\u670d\u5355\u836f\u7597\u6cd5\u4e0e\u5316\u7597\u76f8\u6bd4\u5c55\u73b0\u51fa\u751f\u5b58\u76ca\u5904\u7684\u9996\u4e2aFLT3\u6291\u5236\u5242\u3002<\/span><\/p>\n

6\u3001Eiger\u662f\u4e00\u5bb6\u4e34\u5e8a\u9636\u6bb5\u7684\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u81f4\u529b\u4e8e\u52a0\u901f\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u6cbb\u7597\u7f55\u89c1\u75c5\u53ca\u8d85\u7ea7\u7f55\u89c1\u75c5\u7684\u9776\u5411\u7597\u6cd5\u3002\u8fd1\u65e5\uff0c\u8be5\u516c\u53f8\u516c\u5e03\u4e86\u5b9e\u9a8c\u6027\u836f\u7269avexitide\uff08\u524d\u79f0\uff1aexendin 9-39\uff09\u6cbb\u7597\u51cf\u80a5\u672f\u540e\u4f4e\u8840\u7cd6\u75c7\uff08post-bariatric hypoglycemia\uff0cPBH\uff09\u7684II\u671f\u4e34\u5e8a\u7814\u7a76PREVENT\u7684\u79ef\u6781\u6570\u636e\u3002Avexitide\u662f\u5f00\u53d1\u7528\u4e8ePBH\u7684\u4e00\u79cd\u9996\u521b\uff08first in class\uff09GLP-1\u62ee\u6297\u5242\uff0c\u4f5c\u4e3a\u4e00\u79cd\u65b9\u4fbf\u3001\u65b0\u9896\u7684\u6db2\u4f53\u5236\u5242\uff0c\u53ef\u901a\u8fc7\u76ae\u4e0b\u6ce8\u5c04\u7ed9\u836f\u3002PBH\u662f\u76ee\u524d\u5177\u6709\u9ad8\u5ea6\u672a\u6ee1\u8db3\u533b\u7597\u9700\u6c42\u7684\u7f55\u89c1\u6027\u75be\u75c5\uff0c\u5c1a\u65e0\u83b7\u6279\u6cbb\u7597\u8be5\u75c5\u7684\u836f\u7269\u3002<\/span><\/p>\n

7\u3001\u827e\u5c14\u5efa\uff08Allergan\uff09\u8fd1\u65e5\u5ba3\u5e03\u5df2\u5b8c\u6210ubrogepant\u7528\u4e8e\u504f\u5934\u75db\u6025\u6027\u6cbb\u7597\u76842\u4e2a\u4e34\u5e8a\u7814\u7a76\u5e76\u83b7\u5f97\u4e86\u79ef\u6781\u7684\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u6570\u636e\u3002\u827e\u5c14\u5efa\u5df2\u8ba1\u5212\u57282019\u5e74\u7b2c\u4e00\u5b63\u5ea6\u5411\u7f8e\u56fdFDA\u63d0\u4ea4ubrogepant\u7684\u65b0\u836f\u7533\u8bf7\uff08NDA\uff09\uff0c\u8be5\u516c\u53f8\u9884\u8ba1ubrogepant NDA\u5c06\u6210\u4e3a\u7f8e\u56fd\u5e02\u573a\u63d0\u4ea4\u7684\u7528\u4e8e\u504f\u5934\u75db\uff08\u6709\u6216\u65e0\u5148\u5146\uff09\u6025\u6027\u6cbb\u7597\u7684\u9996\u4e2a\u53e3\u670dCGRP\u53d7\u4f53\u62ee\u6297\u5242\u3002<\/span><\/p>\n

\"\u6bcf\u5468\u836f\u8baf\uff082018\u5e74\u7b2c37\u671f\uff09\"<\/p>\n

8\u3001\u7f8e\u56fd\u751f\u7269\u6280\u672f\u5de8\u5934\u827e\u4f2f\u7ef4\uff08AbbVie\uff09\u8fd1\u65e5\u5ba3\u5e03\uff0c\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40\uff08FDA\uff09\u5df2\u53d7\u7406\u4e86\u9776\u5411\u6297\u764c\u836fImbruvica\uff08ibrutinib\uff0c\u4f9d\u9c81\u66ff\u5c3c\uff09\u7684\u4e00\u4efd\u8865\u5145\u65b0\u836f\u7533\u8bf7\uff08sNDA\uff09\u5e76\u6388\u4e88\u4e86\u4f18\u5148\u5ba1\u67e5\u8d44\u683c\u3002\u8be5sNDA\u5bfb\u6c42\u6279\u51c6Imbruvica\u8054\u5408\u7f57\u6c0f\u6297\u764c\u836fGazyva\uff08obinutuzumab\uff0c\u5965\u59a5\u73e0\u5355\u6297\uff09\u7528\u4e8e\u65e2\u5f80\u672a\u63a5\u53d7\u6cbb\u7597\u7684\uff08\u521d\u6cbb\uff09\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u6216\u5c0f\u6dcb\u5df4\u7ec6\u80de\u6dcb\u5df4\u7624\uff08CLL\/SLL\uff09\u6210\u4eba\u60a3\u8005\u7684\u6cbb\u7597\u3002<\/span><\/p>\n

\"\u6bcf\u5468\u836f\u8baf\uff082018\u5e74\u7b2c37\u671f\uff09\"<\/p>\n

9\u3001\u57fa\u77f3\u836f\u4e1a\uff08\u82cf\u5dde\uff09\u6709\u9650\u516c\u53f8\uff08\u4ee5\u4e0b\u7b80\u79f0\u201c\u57fa\u77f3\u836f\u4e1a\u201d\uff09\u8fd1\u65e5\u5ba3\u5e03\uff0c\u5176\u81ea\u4e3b\u5f00\u53d1\u7684PD-L1\u5355\u514b\u9686\u6297\u4f53\u836f\u7269CS1001\u5df2\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40\uff08FDA\uff09\u9881\u53d1\u7684\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\uff08IND\uff09\u6279\u4ef6\u3002\u8fd9\u4e5f\u6807\u5fd7\u7740\u57fa\u77f3\u836f\u4e1a\u9996\u4e2a\u836f\u7269\u5728\u7f8e\u56fd\u5e02\u573a\u83b7\u5f97IND\u6279\u4ef6\uff0c\u8be5\u516c\u53f8\u8868\u793a\uff0c\u671f\u671b\u7740\u5728\u672a\u6765\u8fdb\u4e00\u6b65\u5411\u7f8e\u56fdFDA\u63d0\u4ea4\u5176\u81ea\u4e3b\u5f00\u53d1\u7684\u5176\u4ed6\u7ba1\u7ebf\u836f\u7269\u7684IND\u7533\u8bf7\u3002<\/span><\/p>\n

\"\u6bcf\u5468\u836f\u8baf\uff082018\u5e74\u7b2c37\u671f\uff09\"<\/p>\n

10\u3001\u5236\u836f\u5de8\u5934\u8f89\u745e\uff08Pfizer\uff09\u8fd1\u65e5\u5ba3\u5e03\uff0c\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40\uff08FDA\uff09\u5df2\u6279\u51c6\u9776\u5411\u6297\u764c\u836fTalzenna\uff08talazoparib\uff09\uff0c\u7528\u4e8e\u5b58\u5728\u6709\u5bb3\u6216\u7591\u4f3c\u6709\u5bb3\u7684\u751f\u6b96\u7cfbBRCA\u7a81\u53d8\uff08gBRCAm\uff09\u3001HER2\u9634\u6027\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u4e73\u817a\u764c\uff08MBC\uff09\u60a3\u8005\u7684\u6cbb\u7597\u3002\u7528\u836f\u65b9\u9762\uff0cTalzenna\u7684\u63a8\u8350\u5242\u91cf\u4e3a\u6bcf\u65e5\u53e3\u670d\u4e00\u6b211mg\uff0c\u4e0e\u98df\u7269\u6216\u4e0d\u4e0e\u98df\u7269\u540c\u670d\u3002\u4e4b\u524d\uff0cFDA\u5df2\u6388\u4e88Talzenna\u4f18\u5148\u5ba1\u67e5\u8d44\u683c\u3002<\/span><\/p>\n

11\u3001\u82cf\u5dde\u5eb7\u5b81\u6770\u745e\u751f\u7269\u79d1\u6280\u6709\u9650\u516c\u53f8\uff08\u4ee5\u4e0b\u7b80\u79f0\u201c\u5eb7\u5b81\u6770\u745e\u201d\uff09\u8fd1\u65e5\u5ba3\u5e03\uff0c\u5176\u81ea\u4e3b\u5f00\u53d1\u7684\u91cd\u7ec4HER2\u53cc\u7279\u5f02\u6027\u6297\u4f53\u6ce8\u5c04\u6db2\uff08KN026\uff09\u5df2\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40\uff08FDA\uff09\u9881\u53d1\u7684\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\uff08IND\uff09\u6279\u4ef6\u3002\u8be5\u516c\u53f8\u6700\u8fd1\u5df2\u542f\u52a8\u4e86KN026\u5728\u4e2d\u56fd\u7684I\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u76ee\u524d\u8be5\u8bd5\u9a8c\u8fdb\u5c55\u4e00\u5207\u987a\u5229\u3002<\/span><\/p>\n

12\u3001\u6cd5\u56fd\u5236\u836f\u5de8\u5934\u8d5b\u8bfa\u83f2\uff08Sanofi\uff09\u4e0e\u5408\u4f5c\u4f19\u4f34\u518d\u751f\u5143\uff08Regeneron\uff09\u8fd1\u65e5\u8054\u5408\u5ba3\u5e03\uff0c\u8bc4\u4f30\u6297\u708e\u836fDupixent\uff08dupilumab\uff09\u6cbb\u7597\u75c5\u60c5\u63a7\u5236\u4e0d\u4f73\u7684\u6162\u6027\u9f3b-\u9f3b\u7aa6\u708e\u4f34\u9f3b\u606f\u8089\uff08chronic rhinosinusitis with nasal polypsis\uff0cCRSwNP\uff09\u6210\u4eba\u60a3\u8005\u76842\u9879\u5173\u952e\u6027\u5b89\u6170\u5242\u5bf9\u7167III\u671f\u4e34\u5e8a\u7814\u7a76\u8fbe\u5230\u4e86\u6240\u6709\u4e3b\u8981\u7ec8\u70b9\u548c\u6b21\u8981\u7ec8\u70b9\u3002<\/span><\/p>\n

13\u3001\u82f1\u56fd\u5236\u836f\u5de8\u5934\u963f\u65af\u5229\u5eb7\uff08AstraZeneca\uff09\u4e0e\u5408\u4f5c\u4f19\u4f34\u9ed8\u6c99\u4e1c\uff08Merck & Co\uff09\u8fd1\u65e5\u8054\u5408\u5ba3\u5e03\uff0c\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40\uff08FDA\uff09\u5df2\u6388\u4e88Lynparza\uff08\u4e2d\u6587\u54c1\u724c\u540d\uff1a\u5229\u666e\u5353\uff0c\u901a\u7528\u540d\uff1aolaparib\uff0c\u5965\u62c9\u5e15\u5229\uff09\u6cbb\u7597\u80f0\u817a\u764c\u7684\u5b64\u513f\u836f\u8d44\u683c\uff08ODD\uff09\u3002\u6b64\u6b21ODD\u4e5f\u662fLynparza\u83b7FDA\u6388\u4e88\u7684\u7b2c4\u4e2aODD\uff0c\u4e4b\u524d\u6388\u4e88\u76843\u4e2aODD\u5206\u522b\u4e3a\uff1a\u6cbb\u7597\u5375\u5de2\u764c\uff082013\u5e74\uff09\u4ee5\u53ca\u8f93\u5375\u7ba1\u764c\uff082018\u5e74\uff09\u548c\u539f\u53d1\u6027\u8179\u819c\u764c\uff082018\uff09\u3002<\/span><\/p>\n

\"\u6bcf\u5468\u836f\u8baf\uff082018\u5e74\u7b2c37\u671f\uff09\"<\/p>\n

14\u300110\u670815\u65e5\uff0c\u9999\u96ea\u751f\u547d\u79d1\u5b66\u516c\u53f8\u548cAthenex\u5ba3\u5e03\u63a5\u53d7TCR-T\u7ec6\u80de\u7597\u6cd5\uff08TAEST\uff09\u60a3\u8005\u7684\u521d\u6b65\u4e34\u5e8a\u7ed3\u679c\u663e\u793a\u51fa\u4ee4\u4eba\u632f\u594b\u7684\u9633\u6027\u4fe1\u53f7\u3002<\/span><\/p>\n

\"\u6bcf\u5468\u836f\u8baf\uff082018\u5e74\u7b2c37\u671f\uff09\"<\/p>\n

15\u3001\u8fd1\u65e5\uff0c\u9ed8\u6c99\u4e1c\u4e0e\u5408\u4f5c\u4f19\u4f34\u4e09\u661fBioepis\u5df2\u7ec8\u6b62\u4e86\u6709\u5173\u8d5b\u8bfa\u83f2\u8d85\u7ea7\u91cd\u78c5\u80f0\u5c9b\u7d20\u4ea7\u54c1\u6765\u5f97\u65f6\uff08Lantus\uff0c\u7518\u7cbe\u80f0\u5c9b\u7d20\uff09\u751f\u7269\u4eff\u5236\u836f\u7684\u5f00\u53d1\u3002\u6839\u636e\u97e9\u56fd\u8bc1\u5238\u4ea4\u6613\u6240\u7684\u4e00\u4efd\u516c\u5f00\u8868\u683c\uff0c\u9ed8\u6c99\u4e1c\u5c06\u652f\u4ed8\u4e09\u661fBioepis\u4e00\u7b141.55\u4ebf\u7f8e\u5143\u7684\u7ec8\u6b62\u8d39\u3002\u8be5\u8868\u683c\u8fd8\u900f\u9732\uff0c\u4e09\u661fBioepis\u5df2\u4e3a\u6765\u5f97\u65f6\u751f\u7269\u4eff\u5236\u53d1\u6295\u5165\u7d2f\u8ba1\u7ea69100\u4e07\u7f8e\u5143\uff0c\u6b64\u6b21\u5408\u4f5c\u7ec8\u6b62\uff0c\u4e09\u661fBioepis\u5c06\u4ece\u4e2d\u83b7\u5f97\u5927\u7ea66400\u4e07\u7f8e\u5143\u7684\u51c0\u5229\u6da6\u3002<\/span><\/p>\n

16\u3001\u7cd6\u5c3f\u75c5\u5de8\u5934\u8bfa\u548c\u8bfa\u5fb7\uff08Novo Nordisk\uff09\u8fd1\u65e5\u5728\u7b2c44\u5c4a\u56fd\u9645\u513f\u79d1\u548c\u9752\u5c11\u5e74\u7cd6\u5c3f\u75c5\u5b66\u4f1a\uff08ISPAD\uff09\u5e74\u5ea6\u4f1a\u8bae\u4e0a\u516c\u5e03\u4e86Fiasp\uff08fast-acting insulin aspart\uff0c\u901f\u6548\u95e8\u51ac\u80f0\u5c9b\u7d20\uff09IIIa\u671f\u4e34\u5e8a\u7814\u7a76ONSET-7\u7684\u6570\u636e\u3002\u6570\u636e\u663e\u793a\uff0c\u5f53\u7528\u4f5c\u6bcf\u65e5\u591a\u6b21\u6ce8\u5c04\u65b9\u6848\uff08\u53c8\u540dbasal-bolus regimen\uff0c\u57fa\u7840+\u9910\u65f6\u6cbb\u7597\u65b9\u6848\uff09\u7684\u4e00\u90e8\u5206\u65f6\uff0c\u4e0e\u5e38\u89c4\u95e8\u51ac\u80f0\u5c9b\u7d20\u76f8\u6bd4\uff0cFiasp\u53ef\u4ee5\u66f4\u597d\u5730\u63a7\u5236\u8840\u7cd6\u6c34\u5e73\u3002<\/span><\/p>\n

17\u3001\u65e5\u524d\uff0c\u9ed8\u514b\u516c\u53f8\u516c\u5e03\u4e86evobrutinib\u6cbb\u7597\u590d\u53d1\u6027\u591a\u53d1\u6027\u786c\u5316\u75c7\u4e8c\u671f\u8bd5\u9a8c\u6570\u636e\u3002\u8fd9\u662f\u4e00\u9879\u4e24\u9879\u968f\u673a\u3001\u5b89\u6170\u5242\u5bf9\u7167\u7684\u4e8c\u671f\u8bd5\u9a8c\u7ed3\u679c\u663e\u793a\uff0c\u6bcf\u65e5\u4e00\u6b21\u548c\u6bcf\u65e5\u4e24\u6b21\u4f7f\u752875mg evobrutinib\u6cbb\u7597\u7684\u591a\u53d1\u6027\u786c\u5316\u60a3\u8005\u75c7\u72b6\u5747\u53d1\u751f\u4e86\u663e\u7740\u51cf\u8f7b\u3002<\/span><\/p>\n

18\u3001\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u5de8\u5934\u767e\u65f6\u7f8e\u65bd\u8d35\u5b9d\uff08BMS\uff09\u8fd1\u65e5\u5ba3\u5e03\u4e86PD-1\u80bf\u7624\u514d\u75ab\u7597\u6cd5Opdivo\uff08\u4e2d\u6587\u5546\u54c1\u540d\uff1a\u6b27\u72c4\u6c83\uff0c\u901a\u7528\u540d\uff1a\u7eb3\u6b66\u5229\u5c24\u5355\u6297[nivolumab]\uff09\u4e8c\u7ebf\u6cbb\u7597\u5c0f\u7ec6\u80de\u80ba\u764c\uff08SCLC\uff09\u7684III\u671f\u4e34\u5e8a\u7814\u7a76CheckMate-331\u7684\u9876\u7ebf\u7ed3\u679c\u3002\u7ed3\u679c\u663e\u793a\uff0c\u8be5\u7814\u7a76\u6ca1\u6709\u8fbe\u5230\u4e3b\u8981\u7ec8\u70b9\u3002<\/span><\/p>\n

19\u3001Sutro Biopharma\u662f\u4e00\u5bb6\u4e34\u5e8a\u9636\u6bb5\u7684\u836f\u7269\u53d1\u73b0\u3001\u5f00\u53d1\u53ca\u5236\u9020\u516c\u53f8\uff0c\u81f4\u529b\u4e8e\u5229\u7528\u7cbe\u786e\u7684\u86cb\u767d\u8d28\u5de5\u7a0b\u53ca\u5408\u7406\u7684\u8bbe\u8ba1\uff0c\u5f00\u53d1\u65b0\u4e00\u4ee3\u7684\u80bf\u7624\u5b66\u7597\u6cd5\u3002\u8fd1\u65e5\uff0c\u8be5\u516c\u53f8\u5ba3\u5e03\uff0c\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40\uff08FDA\uff09\u5df2\u6388\u4e88STRO-001\u6cbb\u7597\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\uff08MM\uff09\u7684\u5b64\u513f\u836f\u8d44\u683c\u3002STRO-001\u662f\u4e00\u79cd\u6f5c\u5728\u7684\u9996\u521b\u6297\u4f53\u836f\u7269\u5076\u8054\u7269\uff08ADC\uff09\uff0c\u9776\u5411CD47\uff0c\u8fd9\u662f\u4e00\u79cd\u5728B\u7ec6\u80de\u6076\u6027\u80bf\u7624\uff08\u5982MM\uff09\u4e2d\u9ad8\u5ea6\u8868\u8fbe\u7684\u86cb\u767d\u3002<\/span><\/p>\n

20\u3001AcelRx\u5236\u836f\u516c\u53f8\u8fd1\u65e5\u5ba3\u5e03\uff0c\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40\uff08FDA\uff09\u9ebb\u9189\u548c\u9547\u75db\u836f\u7269\u4ea7\u54c1\u54a8\u8be2\u59d4\u5458\u4f1a\uff08AADPAC\uff09\u5df2\u53ec\u5f00\u4f1a\u8bae\u5bf9\u8be5\u516c\u53f8\u6b62\u75db\u836fDzuveo\uff08\u8212\u82ac\u592a\u5c3c\u820c\u4e0b\u7247\uff09\u8fdb\u884c\u4e86\u8868\u51b3\uff0c\u8be5\u59d4\u5458\u4f1a\u4ee510\u7968\u8d5e\u6210\u30013\u7968\u53cd\u5bf9\u7684\u6295\u7968\u7ed3\u679c\uff0c\u5efa\u8bae\u6279\u51c6Dsuvia\u7528\u4e8e\u533b\u7597\u76d1\u6d4b\u73af\u5883\u4e2d\u6210\u4eba\u6025\u6027\u4e2d\u5ea6\u81f3\u91cd\u5ea6\u75bc\u75db\u7684\u7ba1\u7406\u3002Dsuvia\u9488\u5bf9\u73b0\u6709\u6cbb\u7597\u65b9\u6848\u7684\u6311\u6218\u800c\u5f00\u53d1\uff0c\u820c\u4e0b\u542b\u670d\uff0c\u6613\u4e8e\u7ed9\u836f\uff0c\u5e76\u4e14\u6700\u5feb\u53ef\u572815\u5206\u949f\u5185\u5feb\u901f\u7f13\u89e3\u75bc\u75db\u3002<\/span><\/p>\n

21\u3001\u65e5\u524d\uff0ctrion\u516c\u53f8\u548c\u5176\u5408\u4f5c\u4f19\u4f34\u68af\u74e6\uff08Teva Pharmaceutical Industries\uff09\u516c\u53f8\u8054\u5408\u5ba3\u5e03\uff0c\u7f8e\u56fdFDA\u7684\u80bf\u7624\u836f\u7269\u54a8\u8be2\u59d4\u5458\u4f1a\u5168\u7968\u63a8\u8350FDA\u6279\u51c6trion\u516c\u53f8\u7814\u53d1\u7684CT-P10\uff0c\u7528\u4e8e\u4f5c\u4e3a\u5355\u4e00\u7597\u6cd5\uff0c\u7ec4\u5408\u7597\u6cd5\u7684\u4e00\u90e8\u5206\u6216\u8005\u7ef4\u6301\u7597\u6cd5\uff0c\u6cbb\u7597B\u7ec6\u80de\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff08NHL\uff09\u3002CT-P10\u662f\u4e00\u79cdCD20\u7684\u5355\u514b\u9686\u6297\u4f53\uff0c\u5b83\u662fRituxan\uff08rituximab\uff09\u7684\u751f\u7269\u4eff\u5236\u836f\u3002\u5982\u679c\u83b7\u5f97\u6279\u51c6\uff0cCT-P10\u5c06\u6210\u4e3a\u7b2c\u4e00\u6b3e\u5728\u7f8e\u56fd\u83b7\u6279\u7684rituximab\u751f\u7269\u4eff\u5236\u836f\u3002\u5b83\u5df2\u7ecf\u5728\u5305\u62ec\u6b27\u76df\u6210\u5458\u56fd\u548c\u97e9\u56fd\u5728\u5185\u768440\u4e2a\u56fd\u5bb6\u83b7\u5f97\u6279\u51c6\u6210\u4e3arituximab\u7684\u751f\u7269\u4eff\u5236\u836f\u3002<\/span><\/p>\n

22\u3001\u5fb7\u56fd\u5236\u836f\u5de8\u5934\u62dc\u8033\uff08Bayer\uff09\u4e0e\u5408\u4f5c\u4f19\u4f34\u7f8e\u56fd\u533b\u836f\u5de8\u5934\u5f3a\u751f\uff08JNJ\uff09\u8fd1\u65e5\u8054\u5408\u5ba3\u5e03\uff0c\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40\uff08FDA\uff09\u5df2\u6279\u51c6\u53e3\u670d\u6297\u51dd\u8840\u5242Xarelto\uff08\u4e2d\u6587\u54c1\u724c\u540d\uff1a\u62dc\u745e\u59a5\uff0c\u901a\u7528\u540d\uff1arivaroxaban\uff0c\u5229\u4f10\u6c99\u73ed\uff09\u4e00\u4e2a\u65b0\u7684\u9002\u5e94\u75c7\uff1aXarelto\uff082.5mg\uff0c\u6bcf\u65e52\u6b21\uff09\u8054\u5408\u4f4e\u5242\u91cf\u963f\u53f8\u5339\u6797\uff08\u6bcf\u65e5\u4e00\u6b21\uff09\uff0c\u7528\u4e8e\u7f79\u60a3\u51a0\u72b6\u52a8\u8109\u75be\u75c5\uff08CAD\uff09\u6216\u5916\u5468\u52a8\u8109\u75be\u75c5\uff08PAD\uff09\u6210\u4eba\u60a3\u8005\uff0c\u964d\u4f4e\u4e3b\u8981\u5fc3\u8840\u7ba1\u4e8b\u4ef6\uff08MACE\uff0c\u5305\u62ec\u5fc3\u8840\u7ba1\u6b7b\u4ea1\u3001\u5fc3\u810f\u75c5\u53d1\u4f5c\u3001\u4e2d\u98ce\uff09\u98ce\u9669\u3002\u636e\u4f30\u8ba1\uff0c\u5728\u7f8e\u56fd\u6709\u8d85\u8fc71300\u4e07\u4f8bCAD\u548cPAD\u60a3\u8005\u3002\u6b64\u6b21\u6279\u51c6\uff0c\u4f7fXarelto\u6210\u4e3a\u9996\u4e2a\u4e5f\u662f\u552f\u4e00\u4e00\u4e2a\u83b7\u6279\u7528\u4e8e\u8fd9\u7c7b\u60a3\u8005\u7fa4\u4f53\u7684\u56e0\u5b50Xa\u6291\u5236\u5242\u3002\u4e4b\u524d\uff0c\u8fd9\u4e00\u65b0\u9002\u5e94\u75c7\u5df2\u83b7\u6b27\u76df\u548c\u52a0\u62ff\u5927\u6279\u51c6\u3002<\/span><\/p>\n

\"\u6bcf\u5468\u836f\u8baf\uff082018\u5e74\u7b2c37\u671f\uff09\"<\/p>\n

23\u3001\u745e\u58eb\u5236\u836f\u5de8\u5934\u8bfa\u534e\uff08Novartis\uff09\u8fd1\u65e5\u516c\u5e03\u4e86\u591a\u53d1\u6027\u786c\u5316\u75c7\uff08MS\uff09\u53e3\u670d\u836f\u7269Gilenya\uff08fingolimod\uff0c\u82ac\u6208\u83ab\u5fb7\uff09IIIb\u671f\u7814\u7a76ASSESS\u7684\u9876\u7ebf\u6570\u636e\u3002\u8fd9\u662f\u4e00\u9879\u968f\u673a\u3001\u5934\u5bf9\u5934\u3001\u8bc4\u5ba1&\u7ed9\u836f\u76f2\u6cd5\u7814\u7a76\uff0c\u5728\u590d\u53d1\u7f13\u89e3\u578b\u591a\u53d1\u6027\u786c\u5316\u75c7\uff08RRMS\uff09\u60a3\u8005\u4e2d\u5f00\u5c55\uff0c\u8bc4\u4f30\u4e862\u79cd\u5242\u91cfGilenya\uff080.25mg\uff0c0.5mg\uff0c\u6bcf\u65e5\u53e3\u670d1\u6b21\uff09\u76f8\u5bf9\u4e8e\u68af\u74e6\u6ce8\u5c04\u4ea7\u54c1Copaxone\uff08\u918b\u9178\u683c\u62c9\u66ff\u96f7\uff0c\u6bcf\u65e5\u4e00\u6b21\u76ae\u4e0b\u6ce8\u5c0420mg\uff09\u6cbb\u7597\u4e3a\u671f\u4e00\u5e74\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\u3002\u8bfa\u534e\u4e8e2012\u5e74\u542f\u52a8\u8be5\u9879\u7814\u7a76\u4f5c\u4e3a\u7f8e\u56fdFDA\u6279\u51c6\u4e0a\u5e02\u540e\u627f\u8bfa\u7684\u4e00\u90e8\u5206\uff0c\u5171\u67091064\u4f8b\u60a3\u8005\u88ab\u7eb3\u5165\u7814\u7a76\uff0c\u5176\u4e2d352\u4f8b\u3001370\u4f8b\u3001342\u4f8b\u968f\u673a\u8fdb\u5165Gilenya 0.5mg\u3001Gilenya 0.25mg\u3001Copaxone 20mg\u6cbb\u7597\u961f\u5217\u3002<\/span><\/p>\n

24\u3001\u7f57\u6c0f\uff08Roche\uff09\u8fd1\u65e5\u5728\u7f8e\u56fd\u65e7\u91d1\u5c71\u4e3e\u884c\u76842018\u5e74\u7f8e\u56fd\u611f\u67d3\u6027\u75be\u75c5\u5468\uff08IDWEEK2018\uff09\u4e0a\u516c\u5e03\u4e86\u8d85\u7ea7\u6d41\u611f\u836f\u7269baloxavir marboxil III\u671f\u4e34\u5e8a\u7814\u7a76CAPSTONE-2\u7684\u79ef\u6781\u6570\u636e\u3002\u8be5\u7814\u7a76\u662f\u4e00\u9879\u591a\u4e2d\u5fc3\u3001\u968f\u673a\u3001\u53cc\u76f2\u7814\u7a76\uff0c\u572812\u5c81\u53ca\u4ee5\u4e0a\u5b58\u5728\u6d41\u611f\u5e76\u53d1\u75c7\u9ad8\u98ce\u9669\u7684\u60a3\u8005\u4e2d\u5f00\u5c55\uff0c\u5c06baloxavir marboxil\u4e0e\u5b89\u6170\u5242\u53ca\u8fbe\u83f2\uff08\u5965\u53f8\u4ed6\u97e6\uff09\u8fdb\u884c\u4e86\u5bf9\u6bd4\u3002\u7f8e\u56fdCDC\u5b9a\u4e49\u7684\u4e25\u91cd\u6d41\u611f\u5e76\u53d1\u75c7\u9ad8\u5371\u4eba\u7fa4\u5305\u62ec\uff1a\u5e74\u9f84\u572865\u5c81\u621665\u5c81\u4ee5\u4e0a\u7684\u8001\u5e74\u4eba\uff0c\u6216\u60a3\u6709\u54ee\u5598\u3001\u6162\u6027\u80ba\u75c5\u3001\u75c5\u6001\u80a5\u80d6\u75c7\u6216\u5fc3\u810f\u75c5\u7684\u60a3\u8005\u3002<\/span><\/p>\n

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\u56fd\u5185\u836f\u7269\u7814\u53d1\u52a8\u6001<\/section>\n<\/section>\n
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1\u3001  \u4fe1\u8fbe\u751f\u7269\u5236\u836f\uff08\u82cf\u5dde\uff09\u6709\u9650\u516c\u53f810\u670818\u65e5\u5ba3\u5e03\uff1a\u7531\u516c\u53f8\u81ea\u4e3b\u5f00\u53d1\u7684\u91cd\u7ec4\u5168\u4eba\u6e90\u6297\u7ec6\u80de\u6bd2T\u6dcb\u5df4\u7ec6\u80de\u76f8\u5173\u6297\u539f-4\uff08CTLA-4\uff09\u5355\u514b\u9686\u6297\u4f53\uff08\u7814\u53d1\u4ee3\u53f7IBI310\uff09\uff0cI\u671f\u4e34\u5e8a\u7814\u7a76\u5df2\u7ecf\u5b8c\u6210\u9996\u4f8b\u60a3\u8005\u7ed9\u836f\u3002<\/span><\/p>\n

2\u300110\u670817\u65e5\uff0c\u56fd\u5bb6\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u603b\u5c40\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3\u53d1\u5e03\u4e86\u62df\u7eb3\u5165\u4f18\u5148\u5ba1\u8bc4\u7a0b\u5e8f\u836f\u54c1\u6ce8\u518c\u7533\u8bf7\u7684\u516c\u793a\uff08\u7b2c\u4e09\u5341\u4e09\u6279\uff09\u3002\u6b64\u6b21\u7b2c\u4e09\u5341\u4e09\u6279\u62df\u7eb3\u5165\u4f18\u5148\u5ba1\u8bc4\u836f\u54c1\uff0c\u517116\u4e2a\uff0c\u6d89\u53ca\u6b63\u5927\u5929\u6674\uff0c\u6c5f\u82cf\u6052\u745e\uff0c\u5b9c\u660c\u4eba\u798f\uff0c\u77f3\u836f\u96c6\u56e2\uff0c\u9f50\u9c81\u5236\u836f\uff0c\u6b4c\u793c\u836f\u4e1a\uff0c\u793c\u6765\u7b49\u591a\u4e2a\u77e5\u540d\u836f\u4f01\u3002\u5728\u8fd916\u4e2a\u836f\u54c1\u4e2d\uff0c\u67094\u4e2a\u4e3a\u65b0\u836f\u4e0a\u5e02\uff0c12\u4e2a\u4e3a\u4eff\u5236\u836f\u4e0a\u5e02\u3002<\/span><\/p>\n

\"\u6bcf\u5468\u836f\u8baf\uff082018\u5e74\u7b2c37\u671f\uff09\"<\/p>\n

3\u300116\u65e5\uff0c\u65e5\u672c\u836f\u4f01\u536b\u6750\u53d1\u5e03\u6d88\u606f\u79f0\uff0c\u5df2\u7533\u8bf7\u5728\u4e2d\u56fd\u5236\u9020\u548c\u9500\u552e\u6297\u766b\u75eb\u836f\u5421\u4ed1\u5e15\u5948\uff0c\u8be5\u836f\u5c06\u4f5c\u4e3a\u5927\u8111\u7279\u5b9a\u90e8\u4f4d\u5f02\u5e38\u5174\u594b\u5f15\u8d77\u7684\u201c\u90e8\u5206\u53d1\u4f5c\u6027\u766b\u75eb\u201d\u7684\u8f85\u52a9\u7597\u6cd5\uff0c\u9002\u7528\u4e8e12\u5c81\u4ee5\u4e0a\u7684\u60a3\u8005\u3002\u9884\u8ba1\u5c06\u4e8e2020\u5e74\u5728\u4e2d\u56fd\u4e0a\u5e02\u3002<\/span><\/p>\n

4\u300110\u670815\u65e5\uff0c\u8f89\u745e\u4e2d\u56fd\u4eca\u65e5\u5ba3\u5e03\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u5df2\u6b63\u5f0f\u6279\u51c6\u8f89\u745e\u516c\u53f8\u7684\u5168\u65b0\u4e00\u4ee3\u9499\u79bb\u5b50\u901a\u9053\u8c03\u8282\u5242\u2014\u2014\u4e50\u745e\u5361\uff08\u666e\u745e\u5df4\u6797\uff09\u7ea4\u7ef4\u808c\u75db\u9002\u5e94\u75c7\u7684\u4e0a\u5e02\u7533\u8bf7\u3002\u7531\u6b64\u4e50\u745e\u5361\u4e5f\u6210\u4e3a\u76ee\u524d\u5728\u534e\u9886\u5148\u83b7\u6279\u4e0a\u5e02\u7684\u7ea4\u7ef4\u808c\u75db\u6cbb\u7597\u836f\u7269\uff0c\u586b\u8865\u4e86\u6211\u56fd\u8be5\u75be\u75c5\u9886\u57df\u6cbb\u7597\u7684\u7a7a\u767d\uff0c\u5728\u4e3a\u6211\u56fd\u7ea4\u7ef4\u808c\u75db\u4e34\u5e8a\u6cbb\u7597\u63d0\u4f9b\u7528\u836f\u4f9d\u636e\u7684\u540c\u65f6\uff0c\u4e5f\u6709\u5229\u4e8e\u63d0\u9ad8\u6211\u56fd\u60a3\u8005\u53ca\u4e34\u5e8a\u533b\u751f\u7684\u75be\u75c5\u8ba4\u77e5\u7a0b\u5ea6\u3002<\/span><\/p>\n

5\u300115\u65e5\uff0c\u6b4c\u793c\u5236\u836f\u5ba3\u5e03\uff0c\u5728\u8fd1\u65e5\u53d1\u5e03\u7684\u300a\u7ecd\u5174\u5e02\u4e19\u578b\u809d\u708e\u9632\u6cbb\u5de5\u4f5c\u63d0\u5347\u884c\u52a8\u65b9\u6848\u300b\u4e2d\uff0c\u6208\u8bfa\u536b\uff08\u8fbe\u8bfa\u745e\u97e6\uff09\u6210\u4e3a\u552f\u4e00\u83b7\u5f97\u8d22\u653f\u8865\u52a9\u7684\u5c0f\u5206\u5b50\u76f4\u63a5\u6297\u4e19\u809d\u75c5\u6bd2\u836f\u7269\u3002<\/span><\/p>\n

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\u673a\u5236\u9776\u70b9\u7814\u7a76\u8fdb\u5c55<\/section>\n<\/section>\n
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1\u3001\u5728\u906d\u53d7\u611f\u67d3\u6216\u7ec4\u7ec7\u635f\u4f24\u540e\uff0c\u708e\u75c7\u6027\u514d\u75ab\u53cd\u5e94\u653b\u51fb\u8fd9\u79cd\u611f\u67d3\u5e76\u4fee\u590d\u53d7\u635f\u7ec4\u7ec7\u3002\u7136\u800c\uff0c\u6709\u65f6\u8fc7\u91cf\u7684\u708e\u75c7\u4f1a\u4ea7\u751f\u76f8\u53cd\u7684\u6548\u679c\uff1a\u5728\u4e00\u79cd\u79f0\u4e3a\u514d\u75ab\u75c5\u7406\u53cd\u5e94\uff08immunopathology\uff09\u7684\u8fc7\u7a0b\u4e2d\uff0c\u8fd9\u4f1a\u589e\u52a0\u7ec4\u7ec7\u635f\u4f24\u3002\u5982\u4eca\uff0c\u5728\u4e00\u9879\u65b0\u7684\u7814\u7a76\u4e2d\uff0c\u6765\u81ea\u897f\u73ed\u7259\u56fd\u5bb6\u5fc3\u8840\u7ba1\u75c5\u7814\u7a76\u4e2d\u5fc3\uff08Centro Nacional de Investigaciones Cardiovasculares, CNIC\uff09\u7684\u7814\u7a76\u4eba\u5458\u53d1\u73b0\u4e86\u4e00\u79cd\u65b0\u7684\u708e\u75c7\u63a7\u5236\u673a\u5236\uff0c\u5b83\u5c55\u793a\u4e86\u5982\u4f55\u63a7\u5236\u7531\u8fd9\u79cd\u708e\u75c7\u6027\u514d\u75ab\u53cd\u5e94\u9020\u6210\u7684\u7ec4\u7ec7\u635f\u4f24\u3002\u76f8\u5173\u7814\u7a76\u7ed3\u679c\u53d1\u8868\u57282018\u5e7410\u670819\u65e5\u7684Science\u671f\u520a\u4e0a\uff0c\u8bba\u6587\u6807\u9898\u4e3a\u201cDNGR-1 in dendritic cells limits tissue damage by dampening neutrophil recruitment\u201d\u3002\u8bba\u6587\u901a\u4fe1\u4f5c\u8005\u4e3a\u897f\u73ed\u7259\u56fd\u5bb6\u5fc3\u8840\u7ba1\u75c5\u7814\u7a76\u4e2d\u5fc3\u7684David Sancho\u548cCarlos del Fresno\u3002<\/span>
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\"\u6bcf\u5468\u836f\u8baf\uff082018\u5e74\u7b2c37\u671f\uff09\"<\/p>\n

2\u3001\u201c\u5e73\u5747\u800c\u8a00\uff0c\u5728\u4eba20\u591a\u5c81\u65f6\u7684\u98df\u9053\u7ec4\u7ec7\u4e2d\uff0c\u6bcf\u4e2a\u5065\u5eb7\u7ec6\u80de\u643a\u5e26\u81f3\u5c11\u51e0\u767e\u4e2a\u7a81\u53d8\uff0c\u968f\u7740\u5e74\u9f84\u7684\u589e\u957f\uff0c\u8fd9\u4e00\u7a81\u53d8\u503c\u4f1a\u589e\u52a0\u81f3\u8d852000\u4e2a\uff01\u201d\u2014\u2014\u8fd9\u662f\u53d1\u8868\u300aScience\u300b\u671f\u520a\u4e0a\u4e00\u7bc7\u6587\u7ae0\u7684\u6700\u65b0\u7ed3\u8bba\uff0c\u5b83\u63ed\u793a\u4e86\u4e00\u4e2a\u201c\u9690\u85cf\u7684\u4e16\u754c\u201d\u3002 \u8fd9\u4e00\u7814\u7a76\u7531Wellcome Sanger\u7814\u7a76\u6240\u548c\u5251\u6865\u5927\u5b66MRC\u764c\u75c7\u7814\u7a76\u4e2d\u5fc3\u7684\u79d1\u5b66\u5bb6\u4eec\u5b8c\u6210\uff0c\u4ed6\u4eec\u53d1\u73b0\uff1a\u5f53\u6b65\u5165\u4e2d\u5e74\uff0c\u5065\u5eb7\u4eba\u8d85\u4e00\u534a\u7684\u98df\u9053\u7ec4\u7ec7\u90fd\u5df2\u88ab\u643a\u5e26\u81f4\u764c\u57fa\u56e0\u7a81\u53d8\u7684\u7ec6\u80de\u6240\u5360\u636e\uff01\u4e5f\u5c31\u662f\u8bf4\uff0c\u4e0e\u764c\u75c7\u76f8\u5173\u7684\u57fa\u56e0\u7a81\u53d8\u5728\u6b63\u5e38\u7ec4\u7ec7\u4e2d\u5e7f\u6cdb\u5b58\u5728\u3002<\/span><\/p>\n

\"\u6bcf\u5468\u836f\u8baf\uff082018\u5e74\u7b2c37\u671f\uff09\"<\/p>\n

3\u3001\u5386\u7ecf\u591a\u5e74\u7814\u7a76\uff0c\u79d1\u5b66\u5bb6\u4eec\u53d1\u5e03\u4e86\u4e00\u4e2a\u5e9e\u5927\u7684\u6570\u636e\u96c6\uff0c\u8be6\u7ec6\u63cf\u8ff0\u4e86500\u591a\u540d\u60a3\u6709\u6025\u6027\u9ad3\u7ec6\u80de\u6027\u767d\u8840\u75c5\uff08Acute myeloid leukemia\uff0cAML\uff09\u60a3\u8005\u80bf\u7624\u7ec6\u80de\u7684\u5206\u5b50\u7ec4\u6210\u3002\u8be5\u6570\u636e\u96c6\u5305\u62ec\u6570\u767e\u4e2a\u4e2a\u4f53\u60a3\u8005\u7684\u7ec6\u80de\u5982\u4f55\u5728\u5b9e\u9a8c\u5ba4\u4e2d\u5bf9\u4e00\u7cfb\u5217\u836f\u7269\u505a\u51fa\u53cd\u5e94\uff0c\u4e3a\u65e5\u540e\u5bf9\u4e8eAML\u7684\u7814\u7a76\u8fdb\u4e00\u6b65\u6253\u4e0b\u57fa\u7840\u300210\u670817\u65e5,\u300aNature\u300b\u6742\u5fd7\u4ee5\u201cFunctional genomic landscape of acute myeloid leukaemia\u201d\u4e3a\u9898\u62a5\u9053\u4e86\u8fd9\u9879\u7814\u7a76\u3002<\/span><\/p>\n

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<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

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