{"id":60982,"date":"2018-10-23T01:00:00","date_gmt":"2018-12-07T03:03:28","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/12\/07\/3fbf97b02b\/"},"modified":"2018-12-07T11:03:30","modified_gmt":"2018-12-07T03:03:30","slug":"3fbf97b02b","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/60982\/","title":{"rendered":"Nature\u7efc\u8ff0\uff1a\u5168\u7403\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u6709\u54ea\u51e0\u5927\u8d8b\u52bf\uff1f"},"content":{"rendered":"
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\u258e\u836f\u660e<\/span><\/strong>\u5eb7\u5fb7\u7f16\u8bd1\u6574\u7406\uff08\u6765\u6e90\uff1a\u300aNature Reviews Drug Discovery\u300b\uff09<\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/h1>\n

\u7f16\u8005\u6309\uff1a<\/span><\/strong>\u81eaipilimumab\u4e8e2011\u5e74\u83b7\u6279\u4ee5\u6765\uff0c\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u5728\u4e0d\u5230\u5341\u5e74\u7684\u65f6\u95f4\u91cc\uff0c\u6539\u5199\u4e86\u4eba\u7c7b\u5bf9\u4e8e\u764c\u75c7\u7684\u6cbb\u7597\u683c\u5c40\u3002\u672c\u6708\u521d\uff0c\u4e24\u540d\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u7684\u5148\u9a71\u4e5f\u83b7\u5f97\u4e862018\u5e74\u8bfa\u8d1d\u5c14\u751f\u7406\u5b66\u6216\u533b\u5b66\u5956\u3002\u5728\u98ce\u5149\u65e0\u9650\u7684\u5f53\u4e0b\uff0c\u5168\u7403\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u5c55\u73b0\u51fa\u4e86\u600e\u6837\u7684\u53d1\u5c55\u8d8b\u52bf\uff1f\u8fd1\u65e5\uff0c\u7ebd\u7ea6\u764c\u75c7\u7814\u7a76\u6240\uff08Cancer Research Institute\uff09\u7684\u5510\u94a7\u535a\u58eb\u7b49\u5b66\u8005\u5728\u300aNature Reviews Drug Discovery\u300b\u4e0a\u520a\u767b\u4e86\u4e00\u7bc7\u6df1\u5ea6\u7efc\u8ff0\uff0c\u5c31\u8fd9\u4e00\u7a81\u7834\u6027\u7597\u6cd5\u7684\u53d1\u5c55\u8d8b\u52bf\u505a\u4e86\u8be6\u5c3d\u7684\u5206\u6790\u3002\u4eca\u5929\u7684\u8fd9\u7bc7\u6587\u7ae0\u4e2d\uff0c\u56e2\u961f\u4e5f\u5c06\u4e3a\u5404\u4f4d\u8bfb\u8005\u4ecb\u7ecd\u5176\u4e2d\u7684\u5185\u5bb9\u3002<\/span>
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\"Nature\u7efc\u8ff0\uff1a\u5168\u7403\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u6709\u54ea\u51e0\u5927\u8d8b\u52bf\uff1f\"<\/p>\n

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\"Nature\u7efc\u8ff0\uff1a\u5168\u7403\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u6709\u54ea\u51e0\u5927\u8d8b\u52bf\uff1f\"<\/p>\n


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2018\u5e74\uff0c\u5171\u6709655\u4e2a\u516c\u53f8\u4e0e\u673a\u6784\u6b63\u5728\u79ef\u6781\u7814\u53d1\u514d\u75ab\u7597\u6cd5\uff0c\u8fd9\u4e00\u6570\u5b57\u8f83\u53bb\u5e74\u540c\u671f\u589e\u957f42%\u3002<\/span><\/strong>\u5982<\/span>\u4eba\u4eec\u6240\u6599\uff0c\u6700\u4e3a\u6d3b\u8dc3\u7684\u516c\u53f8\u4e0e\u673a\u6784\u699c\u5355\u4e0a\uff0c\u524d8\u540d\u5747\u4e3a\u5927\u578b\u533b\u836f\u4f01\u4e1a\u3002\u4f46\u503c\u5f97\u4e00\u63d0\u7684\u662f\uff0c\u5b66\u672f\u79d1\u7814\u673a\u6784\u4e5f\u6b63\u5728\u626e\u6f14\u8d8a\u6765\u8d8a\u91cd\u8981\u7684\u89d2\u8272\u3002\u5728\u8fd9\u4efd\u699c\u5355\u7684\u524d15\u540d\u91cc\uff0c\u67094\u5bb6\u5c5e\u4e8e\u79d1\u7814\u673a\u6784\uff0c\u5176\u4e2d\u4e09\u5bb6\u6765\u81ea\u4e2d\u56fd<\/strong>\uff0c\u5b83\u4eec\u5206\u522b\u662f\u6df1\u5733\u5e02\u514d\u75ab\u57fa\u56e0\u6cbb\u7597\u7814\u7a76\u9662\uff08Shenzhen Geno-Immune Medical Institute\uff09\uff0c\u4e2d\u56fd\u4eba\u6c11\u89e3\u653e\u519b\u603b\u533b\u9662\uff08China PLA General Hospital\uff09\uff0c\u4ee5\u53ca\u7b2c\u4e09\u519b\u533b\u5927\u5b66\u7b2c\u4e00\u9644\u5c5e\u533b\u9662\uff08Third Military Medical University Hospital One\uff09\u3002<\/span><\/p>\n


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[1] Jun Tang et al., (2018), Trends in the global immuno-oncology landscape, Nature Reviews Drug Discovery, DOI: https:\/\/doi.org\/10.1038\/nrd.2018.167<\/span><\/p>\n


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