{"id":61032,"date":"2018-10-11T01:00:00","date_gmt":"2018-12-07T03:03:58","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/12\/07\/2633bff0cb\/"},"modified":"2018-12-07T11:04:00","modified_gmt":"2018-12-07T03:04:00","slug":"2633bff0cb","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/61032\/","title":{"rendered":"\u65b0\u836f\u7814\u53d1\u7684\u65b0\u5174\u529b\u91cf\u2014\u2014\u8d1d\u8fbe\u836f\u4e1a"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"margin-top: 10px;margin-bottom: 20px;font-family: sans-serif;font-size: 14px;line-height: 2;white-space: normal;background-color: rgb(255, 255, 255);text-indent: 2em;text-align: justify;\"><span style=\"font-family: &quot;Times New Roman&quot;, tahoma, verdana, helvetica;text-indent: 28px;font-size: 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LLC\u30022017\u5e746\u6708\uff0c\u8d1d\u8fbe\u6536\u8d2d\u5f20\u6c5f\u751f\u7269\u548c\u5f20\u6c5f\u79d1\u6295\u6301\u6709\u5361\u5357\u5409\u768422.5909%\u80a1\u6743\uff0c\u5b8c\u6210\u6301\u6709\u5361\u5357\u5409100%\u80a1\u6743\u3002<\/span><\/p>\n<p style=\"text-align: justify;margin-top: 10px;margin-bottom: 20px;font-family: sans-serif;font-size: 14px;line-height: 2;white-space: normal;background-color: rgb(255, 255, 255);text-indent: 0em;\"><img class=\"\"     style=\"border-width: 0px;border-style: initial;border-color: initial;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/10-1544151839.jpeg\" alt=\"\u65b0\u53d1\u7684\u65b0\u5174\u529b\u91cf\u2014\u2014\u8d1d\u8fbe\u836f\u4e1a\" title=\"\u65b0\u53d1\u7684\u65b0\u5174\u529b\u91cf\u2014\u2014\u8d1d\u8fbe\u836f\u4e1a\"  \/><\/p>\n<section class=\"_editor\">\n<section class=\"_editor\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;text-align: center;box-sizing: border-box;\">\n<section style=\"display: 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15px;\">\u4ece\u57c3\u514b\u66ff\u5c3c\u7684\u5e74\u9500\u552e\u989d\u6765\u770b\uff0c2012~2016\u5e74\u95f4\uff0c\u57c3\u514b\u66ff\u5c3c\u5e74\u9500\u552e\u989d\u9010\u5e74\u7a33\u6b65\u589e\u957f\uff0c\u4e8e2016\u5e74\u7a81\u783410\u4ebf\u5927\u5173\uff0c\u8fbe10.35\u4ebf\u5143\u30022016\u5e74\u9500\u552e\u989d\u7684\u5f3a\u52b2\u589e\u957f\u4e3b\u8981\u5f97\u76ca\u4e8e2016\u5e74\u4e0b\u534a\u5e74\u5404\u5730\u5f00\u59cb\u9646\u7eed\u6267\u884c\u56fd\u5bb6\u533b\u4fdd\u8c08\u5224\u4ef7\u683c\u7684\u4e3e\u63aa\uff0c2016\u5e745\u6708\uff0c\u8d1d\u8fbe\u627f\u8bfa\u5728\u533b\u4fdd\u8854\u63a5\u7684\u524d\u63d0\u4e0b\uff0c\u5c06\u51ef\u7f8e\u7eb3\u7684\u9500\u552e\u4ef7\u683c\u964d\u4f4e54%\uff08\u964d\u4ef7\u540e\u4e3a1399\u5143\/\u76d2\uff09\u3002\u5728\u8fd9\u79cd\u60c5\u51b5\u4e0b\uff0c\u51ef\u7f8e\u7eb32016\u5e74\u9500\u552e\u91cf\u8fbe\u523056.22\u4e07\u76d2\uff0c\u76f8\u6bd42015\u5e74\u768442.77\u4e07\u76d2\u589e\u957f\u4e8631.46%\u3002\u4f46\u7531\u4e8e\u4ea7\u54c1\u964d\u4ef7\u5e45\u5ea6\u8f83\u5927\uff08\u964d\u4ef754%\uff09\uff0c\u518d\u52a0\u4e0a\u5e02\u573a\u53cd\u5e94\u7684\u6ede\u540e\u6027\uff0c\u9500\u552e\u91cf\u7684\u589e\u91cf\u8fd8\u5728\u91ca\u653e\u5f53\u4e2d\uff0c\u6240\u4ee5\u9500\u552e\u6536\u5165\u4ec5\u5b9e\u73b0\u4e8613.36%\u7684\u540c\u6bd4\u589e\u957f\u30022018\u5e744\u67089\u65e5\uff0c\u8d1d\u8fbe\u53d1\u5e032017\u5e74\u8d22\u62a5\uff0c\u636e\u8d22\u62a5\u663e\u793a\uff0c\u8be5\u516c\u53f82017\u5e74\u5b9e\u73b0\u8425\u653610.263\u4ebf\u5143\uff0c\u540c\u6bd4\u4e0b\u964d0.84%\uff0c\u57c3\u514b\u66ff\u5c3c2017\u5e74\u5b9e\u73b0\u8425\u653610.259\u4ebf\u5143\uff0c\u5360\u516c\u53f8\u603b\u8425\u6536\u8fd1100%\uff08\u56fe2\uff09\u30022018\u5e74\u4e0a\u534a\u5e74\uff0c\u57c3\u514b\u66ff\u5c3c\u201c\u4ee5\u4ef7\u6362\u91cf\u201d\u6548\u679c\u521d\u663e\uff0c\u9500\u552e\u8fbe\u6210\u7387\u8d85\u8fc7\u9884\u671f\uff0c\u4f46\u662f\u5c1a\u672a\u5b9e\u73b0\u201c\u91cf\u4ef7\u6302\u94a9\u201d\u548c\u9500\u552e\u6536\u5165\u7684\u5927\u5e45\u589e\u957f\u3002\u968f\u7740\u56fd\u5bb6\u533b\u7597\u4fdd\u969c\u5c40\u7b49\u6709\u5173\u90e8\u95e8\u843d\u5b9e\u6297\u764c\u836f\u964d\u7a0e\u540e\u7684\u540e\u7eed\u63aa\u65bd\uff0c\u63a8\u52a8\u6297\u764c\u836f\u52a0\u5feb\u964d\u4ef7\uff0c\u8d1d\u8fbe\u79ef\u6781\u914d\u5408\uff0c\u4e8e7\u6708\u5e95\u627f\u8bfa\u5c06\u57c3\u514b\u66ff\u5c3c\u7684\u5404\u7701\u6302\u7f51\u4ef7\u683c\u8fdb\u884c\u8c03\u6574\uff0c\u57282016\u5e74\u56fd\u5bb6\u8c08\u5224\u4ef7\u683c\u7684\u57fa\u7840\u4e0a\u8fdb\u4e00\u6b65\u964d\u4ef73.86%\uff0c\u8c03\u6574\u540e\u4ef7\u683c\u4e3a1345.056\u5143\/\u76d2\uff0c\u8c03\u6574\u540e\u7684\u4ef7\u683c\u6709\u6548\u671f\u81f32019\u5e7412\u670831\u65e5\u3002<\/span><\/p>\n<p style=\"text-align: center;margin-top: 10px;margin-bottom: 20px;font-family: sans-serif;font-size: 14px;line-height: 2;white-space: normal;background-color: rgb(255, 255, 255);text-indent: 0em;\"><img class=\"\"     style=\"border-width: 0px;border-style: initial;border-color: initial;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/0-1544151839.jpeg\" alt=\"\u65b0\u53d1\u7684\u65b0\u5174\u529b\u91cf\u2014\u2014\u8d1d\u8fbe\u836f\u4e1a\" title=\"\u65b0\u53d1\u7684\u65b0\u5174\u529b\u91cf\u2014\u2014\u8d1d\u8fbe\u836f\u4e1a\"  \/><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 20px;font-family: sans-serif;font-size: 14px;line-height: 2;white-space: normal;background-color: rgb(255, 255, 255);text-indent: 2em;text-align: justify;\"><span style=\"font-size: 15px;\">\u9664\u57c3\u514b\u66ff\u5c3c\u5916\uff0c\u8d1d\u8fbe\u8fd8\u6709\u591a\u4e2a\u4e0a\u5e02\u54c1\u79cd\uff0c\u4e3b\u8981\u662f\u8c37\u7ef4\u7d20\u53cc\u7ef4B\u7247\uff08\u8c37\u7ef4\u7d2010mg,\u7ef4\u751f\u7d20B6:5mg,\u7ef4\u751f\u7d20B1:2mg\uff09\u3001\u864e\u53c2\u8f6f\u818f\uff08\u6bcf\u652f\u88c560g\uff09\u3001\u70e7\u4f24\u6b62\u75db\u818f\uff08\u6bcf\u652f\u88c530g\u300140g\u300160g\uff09\u3001\u7ce0\u753e\u9187\u7247\uff0840mg\uff09\u3001\u808c\u9187\u7247\uff080.25g\uff09\u3001\u7ef4\u751f\u7d20B2\u7247\uff085mg\uff09\u3001\u7ef4\u751f\u7d20B2\u7247\uff0810mg\uff09\u3001\u8c37\u7ef4\u7d20\u7247\uff0810mg\uff09\u3002\u4e0a\u5e02\u4ea7\u54c1\u7ec6\u5206\u884c\u4e1a\u53ca\u6309\u6cbb\u7597\u9886\u57df\u5360\u6bd4\u60c5\u51b5\u5982\u56fe3\u6240\u793a\u3002<\/span><\/p>\n<p style=\"text-align: center;margin-top: 10px;margin-bottom: 20px;font-family: sans-serif;font-size: 14px;line-height: 2;white-space: normal;background-color: rgb(255, 255, 255);text-indent: 0em;\"><img loading=\"lazy\" class=\"\"     height=\"404\" style=\"border-width: 0px;border-style: initial;border-color: initial;width: 540px;height: 354px;\" width=\"639\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/1-1544151839.jpeg\" alt=\"\u65b0\u53d1\u7684\u65b0\u5174\u529b\u91cf\u2014\u2014\u8d1d\u8fbe\u836f\u4e1a\" title=\"\u65b0\u53d1\u7684\u65b0\u5174\u529b\u91cf\u2014\u2014\u8d1d\u8fbe\u836f\u4e1a\"  \/><\/p>\n<section class=\"_editor\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;text-align: center;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: top;width: 0.5em;height: 1.8em;border-right: 0.9em solid #8be1e1;border-bottom: 0.9em solid transparent !important;border-top: 0.9em solid transparent !important;box-sizing: border-box;\"><\/section>\n<section style=\"display: inline-block;vertical-align: top;height: 1.8em;line-height: 1.8em;padding-right: 5px;padding-left: 5px;background-color: rgb(139, 225, 225);color: rgb(255, 255, 255);border-radius: 0px 4px 4px 0px;box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\u7814\u7a76\u4e0e\u5f00\u53d1<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-top: 10px;margin-bottom: 20px;font-family: sans-serif;font-size: 14px;line-height: 2;white-space: normal;background-color: rgb(255, 255, 255);text-indent: 2em;text-align: justify;\"><span style=\"font-size: 15px;\">\u4e3a\u4e86\u5e94\u5bf9\u201c\u4e00\u54c1\u72ec\u5927\u201d\u5e26\u6765\u7684\u98ce\u9669\uff0c\u8d1d\u8fbe\u52a0\u7d27\u5f00\u5c55\u65b0\u53d1\u5de5\u4f5c\uff0c\u5f53\u524d\uff0c\u8d1d\u8fbe\u5728\u7814\u9879\u76ee\u8d85\u8fc730\u9879\uff08\u8be6\u7ec6\u8bf7\u89c1\u5b98\u7f51\uff09\uff0c\u6d89\u53ca\u80bf\u7624\uff08\u4e3b\u8981\u9002\u5e94\u75c7\u5305\u62ec\u80be\u764c\u3001\u80ba\u764c\u3001\u809d\u764c\u3001\u80c3\u764c\u3001\u76ae\u80a4\u764c\u3001\u4e73\u817a\u764c\u7b49\uff09\u3001\u7cd6\u5c3f\u75c5\u3001\u5fc3\u8840\u7ba1\u7b49\u591a\u4e2a\u75be\u75c5\u9886\u57df\u3002\u5176\u4e2d\uff0c\u4e3b\u8981\u5728\u7814\u5316\u5b66\u521b\u65b0\u836f\u6709CM082\u3001BPI-15086\u3001BPI-16350\u3001BPI-3016\u3001BPI-9016\u3001X-396\u3001\u8d5b\u897f\u5c3c\u7b49\uff0c\u4e3b\u8981\u5728\u7814\u5316\u5b66\u4eff\u5236\u836f\u6709\u963f\u6258\u4f10\u4ed6\u6c40\u9499\u7247\u3001\u82ef\u4e01\u9178\u94a0\u7247\u3001\u82ef\u78fa\u9178\u6c28\u6c2f\u5730\u5e73\u7247\u3001\u4f0f\u7acb\u8bfa\u4ed6\u80f6\u56ca\u3001\u6c2f\u6cd5\u62c9\u6ee8\u6ce8\u5c04\u6db2\u3001\u7f2c\u6c99\u5766\u80f6\u56ca\u7b49\uff08\u88681\uff09\u3002<\/span><br  \/><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 20px;font-family: sans-serif;font-size: 14px;line-height: 2;white-space: normal;background-color: rgb(255, 255, 255);text-indent: 2em;text-align: justify;\"><span style=\"color: rgb(0, 82, 255);\"><strong><span style=\"font-size: 15px;\">CM082<\/span><\/strong><\/span><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 20px;font-family: sans-serif;font-size: 14px;line-height: 2;white-space: normal;background-color: rgb(255, 255, 255);text-indent: 2em;text-align: justify;\"><span style=\"font-size: 15px;\">CM082\u662f\u4e00\u79cd2-\u5432\u54da\u916e\u7c7b\u9776\u70b9\u7279\u5f02\u6027\u6297\u80bf\u7624\u836f\uff0c\u4e0e\u8212\u5c3c\u66ff\u5c3c\u5177\u6709\u76f8\u4f3c\u9aa8\u67b6\u7ed3\u6784\uff0c\u4e3a\u591a\u9776\u70b9\u53d7\u4f53\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242\uff0c\u4e3b\u8981\u9776\u70b9\u4e3a\u8840\u7ba1\u5185\u76ae\u751f\u957f\u56e0\u5b50\uff08VEGF\uff09\u53d7\u4f53\u548c\u8840\u5c0f\u677f\u751f\u957f\u56e0\u5b50\uff08PDGF\uff09\u53d7\u4f53\u3002\u8be5\u9879\u76ee\u662f\u5728\u5bf9\u8212\u5c3c\u66ff\u5c3c\u4f5c\u7528\u673a\u5236\u548c\u6bd2\u526f\u4f5c\u7528\u5145\u5206\u7814\u7a76\u7684\u57fa\u7840\u4e0a\u5f00\u53d1\u7684\u65b0\u4e00\u4ee3\u4ea7\u54c1\uff0c\u4e34\u5e8a\u4e0a\u8868\u73b0\u51fa\u826f\u597d\u7684\u5b89\u5168\u6027\u548c\u6cbb\u7597\u6548\u679c\u3002\u65e9\u671f\u4e34\u5e8a\u7ed3\u679c\u663e\u793a\uff0cCM082\u5355\u836f\u5bf9\u80be\u764c\u6cbb\u7597\u6548\u679c\u826f\u597d\u3002\u76ee\u524d\u6b63\u5728\u4e2d\u7f8e\u4e24\u56fd\u5f00\u5c55CM082\u5355\u836f\uff0c\u4ee5\u53caCM082\u4e0e\u591a\u897f\u7d2b\u6749\u9187\u3001\u4f9d\u7ef4\u83ab\u53f8\u7b49\u6297\u80bf\u7624\u836f\u8054\u5408\u7528\u836f\u6cbb\u7597\u591a\u79cd\u80bf\u7624\u7684\u4e34\u5e8a\u7814\u7a76\u3002<\/span><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 20px;font-family: sans-serif;font-size: 14px;line-height: 2;white-space: normal;background-color: rgb(255, 255, 255);text-indent: 2em;text-align: justify;\"><span style=\"font-size: 15px;\">\u6b64\u5916\uff0cCM082\u6216\u53ef\u6210\u4e3a\u6297\u773c\u5e95\u9ec4\u6591\u75c5\u53d8\u65b0\u836f\u3002\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\uff08AMD\uff09\u662f\u5f15\u8d77\u5168\u740350\u5c81\u53ca\u4ee5\u4e0a\u8001\u4eba\u5931\u660e\u7684\u6700\u5e38\u89c1\u539f\u56e0\u300210%\u7684AMD\u4e3a\u65b0\u751f\u8840\u7ba1\u6e17\u6f0f\u578b\uff08\u5373\u6e7f\u6027\uff09\uff0c\u4f46\u5176\u5f15\u8d77\u7684\u5931\u660e\u5374\u5360\u523090%\u3002\u76f4\u63a5\u6291\u5236VEGF\/PDGF\u7684\u836f\u7269\u53ef\u5bf9\u6e7f\u6027AMD\u53d1\u6325\u6cbb\u7597\u4f5c\u7528\u3002\u76ee\u524d\u6709\u56db\u79cd\u6297VEGF\u65b0\u836f\u5df2\u5728\u4e34\u5e8a\u5f97\u5230\u5e7f\u6cdb\u5e94\u7528\uff0c\u4e5f\u8868\u73b0\u51fa\u826f\u597d\u7684\u6cbb\u7597\u6548\u679c\u3002\u5176\u4e2d\u6700\u4e3a\u77e5\u540d\u548c\u6210\u529f\u7684\u4ee3\u8868\u4e3a\u7f57\u6c0f\u516c\u53f8\u7684Lucentis\u3002\u4f46\u8fd9\u4e9b\u836f\u7269\u7684\u5171\u540c\u70b9\u4e4b\u4e00\u4e3a\u90fd\u662f\u773c\u5e95\u6ce8\u5c04\u7ed9\u836f\u7684\u751f\u7269\u836f\uff0c\u5176\u8fd0\u8f93\u3001\u50a8\u5b58\u3001\u4f7f\u7528\u90fd\u5f88\u4e0d\u4fbf\uff0c\u800c\u4e14\u60a3\u8005\u9700\u6bcf\u4e2a\u6708\u6216\u6bcf\u4e24\u4e2a\u6708\u4e00\u6b21\u73bb\u7483\u4f53\u5185\u6ce8\u5c04\uff1b\u540c\u65f6\u8fd9\u7c7b\u836f\u7684\u4ef7\u683c\u90fd\u5f88\u6602\u8d35\uff0c\u60a3\u8005\u9700\u5e74\u652f\u51fa10\u4e07\u5143\u5de6\u53f3\u3002\u8fd9\u4e24\u4e2a\u7279\u70b9\u4e25\u91cd\u9650\u5236\u4e86\u5b83\u4eec\u7684\u5e94\u7528\u8303\u56f4\uff0c\u7edd\u5927\u591a\u6570\u4e2d\u56fd\u7684\u60a3\u8005\u90fd\u7528\u4e0d\u5230\u6216\u7528\u4e0d\u8d77\u3002CM082\u662fVEGF\/PDGF\u53cc\u9776\u70b9\u6291\u5236\u5242\uff0c\u5176\u6cbb\u7597\u6e7f\u6027AMD\u7684\u4e34\u5e8a\u7814\u7a76\u5728\u7f8e\u56fd\u5df2\u8fdb\u884c\u4e86\u4e24\u5e74\u591a\uff0c\u5728\u4e2d\u56fd\u7684\u4e34\u5e8a\u8bd5\u9a8c\u4e5f\u4e8e2015\u5e742\u6708\u542f\u52a8\u3002\u7f8e\u56fd\u4e34\u5e8a\u8bd5\u9a8c\u5df2\u5b8c\u6210\u4e86\u8d85\u8fc750\u4f4d\u53d7\u8bd5\u60a3\u8005\u7684\u8bd5\u9a8c\uff0c\u4ed6\u4eec\u5bf9CM082\u8868\u73b0\u4e86\u975e\u5e38\u597d\u7684\u8010\u53d7\u6027\uff0c\u6ca1\u6709\u51fa\u73b0\u91cd\u5927\u6216\u5242\u91cf\u9650\u5236\u6027\u6bd2\u6027\u3002\u5728\u603b\u8ba1163\u4e2a\u53d7\u8bd5\u6708\u91cc\uff0c\u5168\u4f53\u75c5\u4eba\u603b\u5171\u53ea\u63a5\u53d7\u4e868\u6b21\u773c\u5e95\u6ce8\u5c04Lucentis\u4ee5\u9632\u6b62\u75c5\u60c5\u6076\u5316\u3002\u8fd9\u4e2a\u7ed3\u679c\u76f8\u5f53\u4e8e\u5e73\u5747\u6bcf\u4eba\u6bcf\u5e74\u63a5\u53d70.59\u6b21\u773c\u5e95\u6ce8\u5c04\uff0c\u8fdc\u4f4e\u4e8e\u5355\u7528Lucentis\u5e73\u5747\u6bcf\u4eba\u6bcf\u5e74\u9700\u8981\u81f3\u5c117\u6b21\u773c\u5e95\u6ce8\u5c04\u7684\u8981\u6c42\u300289%\u7684\u53d7\u8bd5\u8005\u4e0d\u9700\u8981\u4efb\u4f55\u773c\u5e95\u6ce8\u5c04\u5c31\u4fdd\u6301\u4e86\u89c6\u529b\u4e0d\u6076\u5316\u6216\u6709\u6240\u6539\u5584\u3002\u5982\u679cCM082\u7684\u7814\u53d1\u83b7\u5f97\u6210\u529f\uff0c\u5b83\u5c06\u6210\u4e3a\u5168\u7403\u7b2c\u4e00\u4e2a\u6709\u6548\u6cbb\u7597\u6e7f\u6027AMD\u7684\u53e3\u670d\u836f\uff0c\u5177\u6709\u6781\u5927\u7684\u793e\u4f1a\u4ef7\u503c\u548c\u5b66\u672f\u4ef7\u503c\u3002<\/span><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 20px;font-family: sans-serif;font-size: 14px;line-height: 2;white-space: normal;background-color: rgb(255, 255, 255);text-indent: 2em;text-align: justify;\"><strong><span style=\"font-size: 15px;color: rgb(0, 82, 255);\">BPI-15086<\/span><\/strong><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 20px;font-family: sans-serif;font-size: 14px;line-height: 2;white-space: normal;background-color: rgb(255, 255, 255);text-indent: 2em;text-align: justify;\"><span style=\"font-size: 15px;\">BPI-15086\u7531\u8d1d\u8fbe\u836f\u4e1a\u7814\u53d1\uff0c\u76ee\u524d\u5904\u4e8e\u4e34\u5e8aI\u671f\uff0c\u7528\u4e8e\u6cbb\u7597\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3002BPI-15086\u4e8e2015\u5e7411\u6708\u7533\u62a5\u4e2d\u56fd\u5316\u836f1.1\u7c7b\u4e34\u5e8a\u7814\u7a76\uff0c2016\u5e748\u6708\u83b7\u5f97\u4e34\u5e8a\u8bd5\u9a8c\u6279\u4ef6\u3002<\/span><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 20px;font-family: sans-serif;font-size: 14px;line-height: 2;white-space: normal;background-color: rgb(255, 255, 255);text-indent: 2em;text-align: justify;\"><strong><span style=\"font-size: 15px;color: rgb(0, 82, 255);\">BPI-16350<\/span><\/strong><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 20px;font-family: sans-serif;font-size: 14px;line-height: 2;white-space: normal;background-color: rgb(255, 255, 255);text-indent: 2em;text-align: justify;\"><span style=\"font-size: 15px;\">BPI-16350\u7531\u8d1d\u8fbe\u836f\u4e1a\u7814\u53d1\uff0c\u9488\u5bf9\u7684\u9776\u70b9\u4e3a\u7ec6\u80de\u5468\u671f\u86cb\u767d\u4f9d\u8d56\u6027\u6fc0\u91764\/6\uff08CDK4\/6\uff09\uff0c\u4e3b\u8981\u7528\u4e8e\u6cbb\u7597\u6fc0\u7d20\u53d7\u4f53\u9633\u6027\u548c\u4eba\u7c7b\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f532\u9634\u6027\uff08HR\u9633\u6027\/HER2\u9634\u6027\uff09\u7684\u7edd\u7ecf\u540e\u665a\u671f\u6216\u8f6c\u79fb\u4e73\u817a\u764c\u60a3\u8005\uff0c\u8fd8\u53ef\u7528\u4e8e\u542b\u6709Rb\u9633\u6027\u7ec6\u80de\u7684\u5176\u4ed6\u764c\u75c7\u7684\u4e00\u4e8c\u7ebf\u6216\u8054\u5408\u6cbb\u7597\u3002CDK4\/6\u662f\u8c03\u8282\u7ec6\u80de\u5468\u671f\u7684\u5173\u952e\u56e0\u5b50\uff0c\u80fd\u591f\u89e6\u53d1\u7ec6\u80de\u5468\u671f\u4ece\u751f\u957f\u671f\uff08G1\u671f\uff09\u5411DNA\u590d\u5236\u671f\uff08S\u671f\uff09\u8f6c\u53d8\uff0cCDK4\/6\u6291\u5236\u5242\u5c06\u7ec6\u80de\u5468\u671f\u963b\u6ede\u4e8eG1\u671f\uff0c\u4ece\u800c\u8d77\u5230\u6291\u5236\u80bf\u7624\u7ec6\u80de\u589e\u6b96\u7684\u4f5c\u7528\u30022018\u5e742\u6708\u4e2d\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u603b\u5c40\u53d7\u7406\u8be5\u4ea7\u54c1\u7684\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\uff08\u5316\u836f1\u7c7b\uff09, 2018\u5e746\u6708\u83b7\u5f97\u4e34\u5e8a\u8bd5\u9a8c\u6279\u4ef6\u3002<\/span><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 20px;font-family: sans-serif;font-size: 14px;line-height: 2;white-space: normal;background-color: rgb(255, 255, 255);text-indent: 2em;text-align: justify;\"><strong><span style=\"font-size: 15px;color: rgb(0, 82, 255);\">BPI-3016<\/span><\/strong><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 20px;font-family: sans-serif;font-size: 14px;line-height: 2;white-space: normal;background-color: rgb(255, 255, 255);text-indent: 2em;text-align: justify;\"><span style=\"font-size: 15px;\">BPI-3016\u7531\u8d1d\u8fbe\u836f\u4e1a\u7814\u53d1\uff0c\u7528\u4e8e\u6cbb\u7597\u4e8c\u578b\u7cd6\u5c3f\u75c5\u3002BPI-3016\u4e8e2015\u5e749\u6708\u7533\u62a5\u4e2d\u56fd\u5316\u836f1.1\u7c7b\u4e34\u5e8a\u7814\u7a76\uff0c2017\u5e743\u6708\u83b7\u5f97\u4e34\u5e8a\u8bd5\u9a8c\u6279\u4ef6\u3002<\/span><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 20px;font-family: sans-serif;font-size: 14px;line-height: 2;white-space: normal;background-color: rgb(255, 255, 255);text-indent: 2em;text-align: justify;\"><strong><span style=\"font-size: 15px;color: rgb(0, 82, 255);\">BPI-9016<\/span><\/strong><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 20px;font-family: sans-serif;font-size: 14px;line-height: 2;white-space: normal;background-color: rgb(255, 255, 255);text-indent: 2em;text-align: justify;\"><span style=\"font-size: 15px;\">BPI-9016\u7531\u8d1d\u8fbe\u836f\u4e1a\u7814\u53d1\uff0c\u5904\u4e8e\u4e34\u5e8aI\/II\u671f\uff0c\u7528\u4e8e\u6cbb\u7597\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3002\u53e6\u5916\u5176\u7528\u4e8e\u6cbb\u7597\u5b9e\u4f53\u7624\u6b63\u5904\u4e8e\u4e34\u5e8a\u4e00\u671f\u9636\u6bb5\u30022014\u5e742\u6708\uff0c\u8d1d\u8fbe\u9996\u6b21\u5411\u56fd\u5bb6\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u603b\u5c40\u63d0\u4ea4\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\uff08\u5316\u836f1.1\uff09\uff0c2015\u5e743\u6708\u83b7\u5f97\u4e34\u5e8a\u6279\u4ef6\u3002<\/span><\/p>\n<p style=\"text-align: justify;margin-top: 10px;margin-bottom: 20px;font-family: sans-serif;font-size: 14px;line-height: 2;white-space: normal;background-color: rgb(255, 255, 255);\"><img loading=\"lazy\" class=\"\"        height=\"425\" style=\"border-width: 0px;border-style: initial;border-color: initial;width: 100%;height: auto;\" width=\"692\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/5-1544151840.jpeg\" alt=\"\u65b0\u53d1\u7684\u65b0\u5174\u529b\u91cf\u2014\u2014\u8d1d\u8fbe\u836f\u4e1a\" title=\"\u65b0\u53d1\u7684\u65b0\u5174\u529b\u91cf\u2014\u2014\u8d1d\u8fbe\u836f\u4e1a\"  \/><\/p>\n<p style=\"text-align: justify;margin-top: 10px;margin-bottom: 20px;font-family: sans-serif;font-size: 14px;line-height: 2;white-space: normal;background-color: rgb(255, 255, 255);\"><img loading=\"lazy\" class=\"\"         height=\"365\" style=\"border-width: 0px;border-style: initial;border-color: initial;width: 100%;height: auto;\" width=\"525\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/3-1544151840.jpeg\" alt=\"\u65b0\u53d1\u7684\u65b0\u5174\u529b\u91cf\u2014\u2014\u8d1d\u8fbe\u836f\u4e1a\" title=\"\u65b0\u53d1\u7684\u65b0\u5174\u529b\u91cf\u2014\u2014\u8d1d\u8fbe\u836f\u4e1a\"  \/><\/p>\n<section class=\"_editor\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;text-align: center;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: top;width: 0.5em;height: 1.8em;border-right: 0.9em solid #8be1e1;border-bottom: 0.9em solid transparent !important;border-top: 0.9em solid transparent !important;box-sizing: border-box;\"><\/section>\n<section style=\"display: inline-block;vertical-align: top;height: 1.8em;line-height: 1.8em;padding-right: 5px;padding-left: 5px;background-color: rgb(139, 225, 225);color: rgb(255, 255, 255);border-radius: 0px 4px 4px 0px;box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\u53d1\u5c55\u6218\u7565<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-top: 10px;margin-bottom: 20px;font-family: sans-serif;font-size: 14px;line-height: 2;white-space: normal;background-color: rgb(255, 255, 255);text-indent: 2em;text-align: justify;\"><span style=\"font-size: 15px;\">2018\u5e747\u670813\u65e5\uff0c\u8d1d\u8fbe\u836f\u4e1a\u53d1\u5e03\u4e1a\u7ee9\u9884\u544a\u79f0\uff0c\u516c\u53f8\u9884\u8ba12018\u5e741-6\u6708\u5f52\u5c5e\u4e0a\u5e02\u516c\u53f8\u80a1\u4e1c\u7684\u51c0\u5229\u6da6\u4e3a6168.62\u4e07-7539.43\u4e07\u5143\uff0c\u540c\u6bd4\u4e0b\u964d45%-55%\u3002\u8fd9\u5df2\u7ecf\u4e0d\u662f\u8d1d\u8fbe\u836f\u4e1a\u9996\u6b21\u4e1a\u7ee9\u4e0b\u6ed1\u3002\u8d22\u62a5\u6570\u636e\u663e\u793a\uff0c\u8d1d\u8fbe\u836f\u4e1a2017\u5e74\u5b9e\u73b0\u8425\u653610.263\u4ebf\u5143\uff0c\u540c\u6bd4\u4e0b\u964d0.84%\uff1b\u5b9e\u73b0\u5f52\u5c5e\u4e8e\u4e0a\u5e02\u80a1\u4e1c\u7684\u51c0\u5229\u6da6\u4e3a2.58\u4ebf\u5143\uff0c\u540c\u6bd4\u4e0b\u964d30.12%\u3002\u7814\u53d1\u6295\u5165\u7684\u589e\u52a0\u5f71\u54cd\u516c\u53f8\u76c8\u5229\uff0c\u4f46\u8fd9\u53ea\u662f\u5176\u4e2d\u7684\u4e00\u4e2a\u56e0\u7d20\uff0c\u5728\u4e1a\u5185\u4eba\u58eb\u770b\u6765\uff0c\u8fc7\u4e8e\u4f9d\u8d56\u5355\u4e00\u4ea7\u54c1\u57c3\u514b\u66ff\u5c3c\u662f\u8d1d\u8fbe\u836f\u4e1a\u4e1a\u7ee9\u4e0b\u6ed1\u7684\u91cd\u8981\u539f\u56e0\u3002<\/span><br 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lang=\"EN-US\" style=\"font-size: 13.5pt;line-height: 200%;font-family: \u534e\u6587\u7ec6\u9ed1;\"><o:p><\/o:p><\/span><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 20px;line-height: 2;text-align: justify;\"><span style=\"color: rgb(136, 136, 136);font-size: 12px;\">\u3010\u53c2\u8003\u8d44\u6599\u3011<\/span><br  \/><span style=\"font-size: 15px;\"><\/span><\/p>\n<p style=\"text-align: justify;margin-bottom: 5px;margin-top: 5px;line-height: normal;\"><span style=\"color: rgb(136, 136, 136);font-size: 12px;\">1.\u8d1d\u8fbe\u836f\u4e1a\u80a1\u4efd\u6709\u9650\u516c\u53f8\u5b98\u7f51.<\/span><\/p>\n<p style=\"text-align: justify;margin-bottom: 5px;margin-top: 5px;line-height: normal;\"><span style=\"color: rgb(136, 136, 136);font-size: 12px;\">2.\u8d1d\u8fbe\u836f\u4e1a\u80a1\u4efd\u6709\u9650\u516c\u53f82017\u5e74\u5e74\u5ea6\u62a5\u544a.<\/span><\/p>\n<p style=\"text-align: justify;margin-bottom: 5px;margin-top: 5px;line-height: normal;\"><span style=\"color: rgb(136, 136, 136);font-size: 12px;\">3.\u8d1d\u8fbe\u836f\u4e1a\u80a1\u4efd\u6709\u9650\u516c\u53f82018\u5e74\u534a\u5e74\u5ea6\u62a5\u544a\u6458\u8981\uff08\u516c\u544a\u7f16\u53f7\uff1a2018-060\uff09.<\/span><\/p>\n<p style=\"text-align: justify;margin-bottom: 5px;margin-top: 5px;line-height: normal;\"><span style=\"color: rgb(136, 136, 136);font-size: 12px;\">4.insight\u6570\u636e\u5e93,\u68c0\u7d22\u65e5\u671f\uff1a2018\u5e749\u670819\u65e5.<\/span><\/p>\n<p style=\"text-align: justify;margin-bottom: 5px;margin-top: 5px;line-height: normal;\"><span style=\"color: rgb(136, 136, 136);font-size: 12px;\">5.\u7c73\u5185\u7f51\uff0c\u68c0\u7d22\u65e5\u671f\uff1a2018\u5e749\u670827\u65e5.<\/span><\/p>\n<p style=\"text-align: justify;margin-bottom: 5px;margin-top: 5px;line-height: normal;\"><span style=\"color: rgb(136, 136, 136);font-size: 12px;\">6.\u6570\u636e\uff0c\u68c0\u7d22\u65e5\u671f\uff1a2018\u5e749\u670827\u65e5.<\/span><\/p>\n<p style=\"text-align: justify;margin-bottom: 5px;margin-top: 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