{"id":62294,"date":"2018-11-23T01:00:00","date_gmt":"2018-12-07T03:15:38","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/12\/07\/1486c295a0\/"},"modified":"2018-12-07T11:15:43","modified_gmt":"2018-12-07T03:15:43","slug":"1486c295a0","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/62294\/","title":{"rendered":"CDE\u521a\u521a\u53d1\u5e03\uff01\u5173\u4e8e\u516c\u5f00\u5f81\u6c42\u300a\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\u6cbb\u7597\u836f\u7269\u4e34\u5e8a\u7814\u7a76\u6280\u672f\u6307\u5bfc\u539f\u5219\u300b\u610f\u89c1\u7684\u901a\u77e5"},"content":{"rendered":"
\n

\"CDE\u521a\u521a\u53d1\u5e03\uff01\u5173\u4e8e\u516c\u5f00\u5f81\u6c42\u300a\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\u6cbb\u7597\u836f\u7269\u4e34\u5e8a\u7814\u7a76\u6280\u672f\u6307\u5bfc\u539f\u5219\u300b\u610f\u89c1\u7684\u901a\u77e5\"<\/p>\n

\u4e3a\u8fdb\u4e00\u6b65\u8d2f\u5f7b\u300a\u56fd\u52a1\u9662\u5173\u4e8e\u6539\u9769\u836f\u54c1\u533b\u7597\u5668\u68b0\u5ba1\u8bc4\u5ba1\u6279\u5236\u5ea6\u7684\u610f\u89c1\u300b\uff08\u56fd\u53d1\u30142015\u301544\u53f7\uff09\u548c\u300a\u5173\u4e8e\u6df1\u5316\u5ba1\u8bc4\u5ba1\u6279\u5236\u5ea6\u6539\u9769\u9f13\u52b1\u836f\u54c1\u533b\u7597\u5668\u68b0\u521b\u65b0\u7684\u610f\u89c1\u300b\uff08\u5385\u5b57\u30142017\u301542\u53f7\uff09\u7b49\u7cbe\u795e\uff0c\u6211\u4e2d\u5fc3\u9488\u5bf9\u5f53\u524d\u56fd\u5185\u5916\u4e34\u5e8a\u5b58\u5728\u8feb\u5207\u9700\u6c42\u4e14\u7814\u53d1\u70ed\u70b9\u9886\u57df\uff0c\u7ec4\u7ec7\u8d77\u8349\u4e86\u300a\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\u6cbb\u7597\u836f\u7269\u4e34\u5e8a\u7814\u7a76\u6280\u672f\u6307\u5bfc\u539f\u5219\u300b\uff0c\u7ecf\u8fc7\u4e09\u6b21\u4e13\u5bb6\u7814\u8ba8\u4f1a\uff0c\u5c31\u6307\u5357\u6846\u67b6\u3001\u521d\u7a3f\u3001\u4fee\u8ba2\u7a3f\u8fdb\u884c\u4e86\u7814\u8ba8\u5e76\u5f62\u6210\u5f81\u6c42\u610f\u89c1\u7a3f\u3002\u73b0\u516c\u5f00\u5f81\u6c42\u610f\u89c1\uff0c\u8bf7\u5e7f\u5927\u836f\u7269\u7814\u7a76\u76f8\u5173\u4eba\u5458\u63d0\u51fa\u610f\u89c1\u548c\u5efa\u8bae\u3002\u6709\u5173\u4e8b\u9879\u5982\u4e0b\uff1a
<\/span><\/p>\n

\u65f6\u9650\uff1a1\u4e2a\u6708
<\/span><\/p>\n

\u8054\u7cfb\u4eba\uff1a\u8c22\u677e\u6885
<\/span><\/p>\n

\u4fe1\u606f\u53cd\u9988\uff1axiesm @cde.org.cn<\/span><\/p>\n

\u56fd\u5bb6\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u603b\u5c40\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3<\/span><\/p>\n

2018\u5e7411\u670823\u65e5<\/span><\/p>\n


<\/p>\n

\"CDE\u521a\u521a\u53d1\u5e03\uff01\u5173\u4e8e\u516c\u5f00\u5f81\u6c42\u300a\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\u6cbb\u7597\u836f\u7269\u4e34\u5e8a\u7814\u7a76\u6280\u672f\u6307\u5bfc\u539f\u5219\u300b\u610f\u89c1\u7684\u901a\u77e5\"<\/p>\n

\"CDE\u521a\u521a\u53d1\u5e03\uff01\u5173\u4e8e\u516c\u5f00\u5f81\u6c42\u300a\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\u6cbb\u7597\u836f\u7269\u4e34\u5e8a\u7814\u7a76\u6280\u672f\u6307\u5bfc\u539f\u5219\u300b\u610f\u89c1\u7684\u901a\u77e5\"<\/p>\n

1.   \u7b80\u4ecb<\/strong><\/span><\/p>\n

1.1  \u80cc\u666f<\/strong><\/span><\/p>\n

\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\uff08age-relatedmaculardegeneration,AMD\uff09\u662f\u5f15\u8d77\u4e25\u91cd\u7684\u3001\u4e0d\u53ef\u9006\u6027\u89c6\u529b\u635f\u4f24\u7684\u4e3b\u8981\u539f\u56e0[1,2]\u3002\u8be5\u75c5\u591a\u53d1\u751f\u4e8e50 \u5c81\u4ee5\u4e0a\u4eba\u7fa4\uff0c\u5076\u53d1\u4e8e40-50\u5c81\u4eba\u7fa4\u3002\u6d41\u884c\u75c5\u5b66\u8c03\u67e5\u663e\u793a\uff0cAMD\u81f4\u76f2 \u8005\u7ea6\u5360\u5168\u7403\u76f2\u4eba\u76848.7%\uff0c\u5168\u7403\u7ea6\u67093000\u4e07AMD\u60a3\u8005\uff0c\u6bcf\u5e74\u7ea6\u670950\u4e07 \u4eba\u56e0\u4e3aAMD\u800c\u81f4\u76f2\u30103\u3011\u3002\u6211\u56fd50\u5c81\u4ee5\u4e0a\u4eba\u7fa4\u65e9\u671fAMD\u7684\u60a3\u75c5\u7387\u57281.7%-9.5%\u4e4b\u95f4\uff0c\u665a\u671fAMD\u7684\u60a3\u75c5\u7387\u57280.2%-1%\u4e4b\u95f4[3,4]\u3002AMD\u60a3\u75c5 \u7387\u968f\u5e74\u9f84\u589e\u957f\u800c\u589e\u9ad8\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u76ee\u524d\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\uff08AMD\uff09\u7684\u53d1\u75c5\u673a\u5236\u5c1a\u4e0d\u5b8c\u5168\u6e05\u695a\uff0c\u4e00\u822c\u8ba4\u4e3a\u662f\u9057\u4f20\u56e0\u7d20\u4e0e\u73af\u5883\u56e0\u7d20\u4ea4\u4e92\u4f5c\u7528\u7684\u7ed3\u679c\u3002\u8870\u8001\u3001\u4ee3\u8c22\u51cf\u7f13\u4ee5\u53ca\u6c27\u5316\u635f\u4f24\u7b49\u5bfc\u81f4Bruch\u819c\u589e\u539a\u4ee5\u53ca\u8102\u8910\u7d20\u6c89\u79ef\uff0c\u73bb\u7483\u819c\u75a3\u5f62\u6210\uff0c\u5e76\u4ea7 \u751f\u6162\u6027\u708e\u75c7\u523a\u6fc0,\u8fdb\u800c\u5f62\u6210\u65e9\u671fAMD\u3002\u968f\u7740\u75c5\u7a0b\u53d1\u5c55\uff0c\u708e\u75c7\u7b49\u53cd\u5e94\u4e0d\u65ad\u653e\u5927\uff0c\u6700\u7ec8\u53ef\u5bfc\u81f4\u5730\u56fe\u6837\u840e\u7f29\uff08GeographicAtrophy\uff0cGA\uff09\u3001\u548c\u4ee5\u8109 \u7edc\u819c\u65b0\u751f\u8840\u7ba1\u5f62\u6210\u4ee5\u53ca\u51fa\u8840\u3001\u6e17\u51fa\u4e3a\u7279\u5f81\u7684\u65b0\u751f\u8840\u7ba1\u6027\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027(nAMD)\u3002nAMD\u662f\u4e00\u79cd\u8fdb\u5c55\u671fAMD\uff0c\u53ef\u5bfc\u81f4\u5feb\u901f\u91cd\u5ea6\u89c6\u529b\u969c\u788d\uff0c\u662f\u89c6\u529b\u4e27\u5931\u548c\u89c6\u529b\u53d1\u75c5\u7684\u4e3b\u8981\u539f\u56e0\uff08 Bo urneetal.2013\uff1bWongetal.2014\uff09\u3002\u4e34\u5e8a\u53ef\u89c1\u9ec4\u6591\u533a\u8109\u7edc\u819c\u65b0\u751f\u8840\u7ba1\uff08CNV)\u5f15\u8d77\u7684\u51fa\u8840\u3001\u89c6\u7f51\u819c\u5185\u3001\u89c6\u7f51\u819c\u4e0b\u7684\u79ef\u6db2\u3001\u6e17\u51fa\u6027\u6216\u51fa\u8840\u6027\u795e\u7ecf\u4e0a\u76ae\uff0f\u8272\u7d20\u4e0a\u76ae\u8131\u79bb(PED)\u7b49\u75c5\u53d8,\u7ea4\u7ef4\u8840\u7ba1\u6027\u76d8\u72b6\u7622\u75d5\u662f\u65b0\u751f\u8840\u7ba1\u6027AMD\u6700\u7ec8\u7684\u7ed3\u5c405\u3002 \u5df2\u77e5\u8840\u7ba1\u751f\u6210\u3001\u708e\u75c7\u548c\u6c27\u5316\u5e94\u6fc0\u7b49\u591a\u79cd\u751f\u5316\u548c\u751f\u7269\u8fc7\u7a0b\u5728nAMD\u7684\u53d1\u75c5\u673a\u5236\u4e2d\u8d77\u4f5c\u7528\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\uff08AMD\uff09\u7684\u8bca\u65ad\u9700\u8981\u901a\u8fc7\u4e34\u5e8a\u75c7\u72b6\u548c\u76f8\u5173\u773c\u90e8\u68c0\u67e5\u5e2e\u52a9\u8bca\u65ad\uff0c\u773c\u90e8\u68c0\u67e5\u901a\u5e38\u5305\u62ec\u89c6\u529b\u3001\u8fdc\u8fd1\u6700\u4f73\u77eb\u6b63\u89c6\u529b\u3001 \u68c0\u773c\u955c\uff08\u53cc\u76ee\u88c2\u9699\u706f\u663e\u5fae\u955c\u8054\u5408\u524d\u7f6e\u955c\uff09\u53caAmsler\u8868\u68c0\u67e5\u7b49\u3002<\/span><\/p>\n

 <\/span><\/p>\n

AMD\u6cbb\u7597\u7684\u9996\u8981\u76ee\u6807\u662f\u9006\u8f6c\u6216\u6700\u5927\u9650\u5ea6\u5730\u51cf\u5c11\u60a3\u8005\u89c6\u529f\u80fd\u7684\u4e27 \u5931\uff0c\u4ee5\u53ca\u63d0\u9ad8\u89c6\u529f\u80fd\u3002\u76ee\u524d\uff0cAMD\u7684\u6cbb\u7597\u5305\u62ec\u89c2\u5bdf\u3001\u6297\u6c27\u5316\u7ef4\u751f\u7d20\u548c\u77ff\u7269\u8d28\u8865\u5145\u7269\u3001\u73bb\u7483\u4f53\u8154\u5185\u6ce8\u5c04\u6297VEGF\u836f\u7269\u3001\u5149\u52a8\u529b\u7597\u6cd5\u548c\u6fc0\u5149 \u5149\u51dd\u672f\u3002\u6cbb\u7597\u7684\u9009\u62e9\u53d6\u51b3\u4e8e\u75c5\u53d8\u7684\u4e0d\u540c\u7c7b\u578b\u548c\u4e0d\u540c\u9636\u6bb5\u3002\u8fd1\u5e74\u6765\uff0c\u65b0\u751f\u8840\u7ba1\u6027AMD\u6cbb\u7597\u7684\u8fdb\u5c55\u8f83\u5feb\u3002\u65e2\u5f80\u6cbb\u7597\u624b\u6bb5\u5305\u62ec\uff1a\u5149\u51dd\u6cbb\u7597\u8109 \u7edc\u819c\u65b0\u751f\u8840\u7ba1\uff0c\u5149\u52a8\u529b\u7597\u6cd5\uff08Photodynamictherapy,PDT\uff09\u6cbb\u7597\u4e2d\u5fc3 \u51f9\u4e0b\u8109\u7edc\u819c\u65b0\u751f\u8840\u7ba1\uff0c\u4ee5\u53ca\u624b\u672f\u6cbb\u7597\uff08\u5982\u89c6\u7f51\u819c\u4e0b\u819c\u53d6\u51fa\u65b0\u751f\u8840\u7ba1\u819c\u3001\u9ec4\u6591\u8f6c\u4f4d\u672f\u7b49\uff09\u3002\u4f46\uff0c\u6fc0\u5149\u5149\u51dd\u6cbb\u7597\u53ea\u80fd\u51cf\u7f13\u4e25\u91cd\u89c6\u529b\u4e0b\u964d\u7684\u901f\u5ea6\uff0c\u624b\u672f\u6cbb\u7597\u5219\u56e0\u672f\u540e\u8f83\u9ad8\u7684\u5e76\u53d1\u75c7\u5df2\u5f88\u5c11\u4f7f\u7528\u3002\u76ee\u524d\uff0c\u968f\u7740\u6297 VEGF\u836f\u7269\u7684\u4e0a\u5e02\uff0cPDT\u6cbb\u7597\u4e5f\u5df2\u4e0d\u662f\u9996\u9009\u6cbb\u7597\u65b9\u6cd5\uff0c\u6297VEGF\u836f\u7269 \u6210\u4e3a\u4e34\u5e8a\u4e00\u7ebf\u6cbb\u7597\u65b0\u751f\u8840\u7ba1\u6027AMD\u7684\u624b\u6bb5\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u7136\u800c\uff0c\u4e34\u5e8a\u4e0a\u5bf9\u4e8eAMD\u7684\u6cbb\u7597\u4ecd\u7136\u9762\u4e34\u4e00\u4e9b\u672a\u88ab\u6ee1\u8db3\u7684\u6cbb\u7597 \u5b66\u9700\u6c42\u3002\u4f8b\u5982\uff0c\u65b0\u751f\u8840\u7ba1\u6027AMD\u9762\u4e34\u7684\u96be\u9898\u5305\u62ec\uff1a\u5982\u4f55\u7a33\u5b9a\u6216\u51cf \u7f13\u75be\u75c5\u8fdb\u7a0b\uff08\u8bf1\u5bfc\u75c5\u7406\u6027\u8109\u7edc\u819c\u65b0\u751f\u8840\u7ba1\u590d\u5408\u7269\u9000\u5316\uff0c\u4ee5\u53ca\u7ef4\u6301\u6216 \u63d0\u9ad8\u957f\u671f\u7597\u6548\u3001\u51cf\u5c11\u89c6\u7f51\u819c\u840e\u7f29\u548c\u7ea4\u7ef4\u5316\uff09\u3001\u63d0\u9ad8\u7597\u6548\u3001\u51cf\u8f7b\u60a3\u8005 \u6cbb\u7597\u8d1f\u62c5\u4ee5\u53ca\u589e\u52a0\u4f9d\u4ece\u6027\u7b49\u3002\u800c\u5bf9\u4e8eGA\uff0c\u5982\u4f55\u63a7\u5236\u53ca\u9006\u8f6c\u5176\u840e\u7f29 \u4ecd\u662f\u5176\u4e34\u5e8a\u6cbb\u7597\u5b66\u96be\u70b9\u3002<\/span><\/p>\n


<\/p>\n

1.2\u76ee\u7684<\/span><\/strong><\/p>\n

\u672c\u6307\u5bfc\u539f\u5219\u65e8\u5728\u4e3a\u6cbb\u7597\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\u7684\u5316\u5b66\u836f\u7269\u548c\u751f\u7269 \u5236\u54c1\u7684\u5f00\u53d1\u63d0\u4f9b\u6709\u5173\u4e34\u5e8a\u8bd5\u9a8c\u8bbe\u8ba1\u3001\u5b9e\u65bd\u548c\u8bc4\u4ef7\u7684\u65b9\u6cd5\u5b66\u6307\u5bfc\u3002<\/span> <\/span><\/p>\n

 <\/span><\/p>\n

\u836f\u7269\u7684\u4e34\u5e8a\u5f00\u53d1\u9996\u5148\u8981\u9075\u5faa\u836f\u54c1\u4e34\u5e8a\u8bd5\u9a8c\u7684\u4e00\u822c\u539f\u5219\uff0c\u5982\uff1a\u300a\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u7684\u4e00\u822c\u8003\u8651\u6307\u5bfc\u539f\u5219\u300b[10]\u3001\u300a\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u7684\u751f\u7269\u7edf\u8ba1\u5b66 \u6307\u5bfc\u539f\u5219\u300b[9]\u3001\u3001\u300a\u5316\u5b66\u836f\u7269\u4e34\u5e8a\u836f\u4ee3\u52a8\u529b\u5b66\u7814\u7a76\u6280\u672f\u6307\u5bfc\u539f\u5219\u300b[11]\u3001\u300a\u836f\u7269\u76f8\u4e92\u4f5c\u7528\u7814\u7a76\u6307\u5bfc\u539f\u5219\u300b[12]\u7b49\uff0c\u540c\u65f6\u4e5f\u8981\u9075\u5faa\u4e1a\u5df2\u53d1\u5e03\u7684\u5176\u5b83\u76f8\u5173\u4e34\u5e8a\u8bd5\u9a8c\u6280\u672f\u6307\u5bfc\u539f\u5219\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u672c\u6307\u5bfc\u539f\u5219\u662f\u5efa\u8bae\u6027\u7684\uff0c\u4e0d\u662f\u65b0\u836f\u4e0a\u5e02\u6ce8\u518c\u7684\u5f3a\u5236\u6027\u8981\u6c42\u3002\u968f\u7740 \u533b\u5b66\u79d1\u5b66\u548c\u533b\u7597\u5b9e\u8df5\u7684\u53d1\u5c55\uff0c\u75be\u75c5\u8bca\u65ad\u3001\u6cbb\u7597\u7684\u624b\u6bb5\u4f1a\u4e0d\u65ad\u6539\u8fdb\uff0c\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u7684\u8bbe\u8ba1\u8bc4\u4ef7\u65b9\u6cd5\u4e5f\u4f1a\u968f\u4e4b\u66f4\u65b0\u3002\u56e0\u800c\uff0c\u672c\u6307\u5bfc\u539f\u5219\u7684\u89c2\u70b9 \u4e3a\u9636\u6bb5\u6027\u7684\uff0c\u5982\u679c\u968f\u7740\u533b\u5b66\u79d1\u5b66\u7684\u53d1\u5c55\u51fa\u73b0\u4e86\u66f4\u52a0\u79d1\u5b66\u5408\u7406\u548c\u516c\u8ba4\u7684\u65b9\u6cd5\uff0c\u4e5f\u53ef\u4ee5\u91c7\u7528\uff0c\u4f46\u9700\u63d0\u4f9b\u652f\u6301\u6027\u8bc1\u636e\u3002<\/span> <\/span><\/p>\n

 <\/span><\/p>\n

1.3\u9002\u7528\u8303\u56f4<\/span><\/strong><\/p>\n

\u672c\u6307\u5bfc\u539f\u5219\u4e3b\u8981\u9002\u7528\u4e8e\u6cbb\u7597\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027(AMD)\u7684\u751f\u7269 \u5236\u54c1\u4ee5\u53ca\u65b0\u5316\u5408\u7269\u7684\u4e34\u5e8a\u7814\u7a76\uff0c\u91cd\u70b9\u8ba8\u8bba\u57fa\u4e8e\u8fdb\u5c55\u671fAMD(\u65b0\u751f\u8840 \u7ba1\u6027AMD\u548c\uff0f\u6216\u5730\u56fe\u6837\u840e\u7f29)\u7684\u836f\u7269\u7814\u53d1\u548c\u8bd5\u9a8c\u8bbe\u8ba1\u539f\u5219\uff0c\u5bf9\u4e8e\u7531 \u4e8e\u5176\u4ed6\u75c5\u56e0\u5bfc\u81f4\u7684\u8109\u7edc\u819c\u65b0\u751f\u8840\u7ba1\u5f15\u8d77\u7684\u89c6\u529b\u635f\u4f24\u4e5f\u53ef\u53c2\u8003\u672c\u6307\u5bfc\u539f\u5219\u76f8\u5173\u5efa\u8bae\u3002<\/span><\/p>\n


<\/p>\n

2.  AMD\u6cbb\u7597\u836f\u7269\u5f00\u53d1\u7684\u6574\u4f53\u8003\u8651<\/span><\/strong><\/p>\n

2.1  \u9075\u5faa\u4ee5\u76ee\u6807\u4e3a\u5bfc\u5411\u7684\u539f\u5219 <\/span><\/strong><\/p>\n

\u5728\u836f\u7269\u4e34\u5e8a\u6574\u4f53\u7814\u53d1\u7b56\u7565\u4e0a\uff0c\u5e94\u91c7\u7528\u4ee5\u76ee\u6807\u4e3a\u5bfc\u5411\uff0c\u5e76\u7d27\u5bc6\u56f4<\/span>\u7ed5\u836f\u54c1<\/span>\u8bf4<\/span>\u660e\u4e66<\/span>\u5236<\/span>\u5b9a\u7684<\/span>\u76ee<\/span>\u6807\u5185<\/span>\u5bb9<\/span>\u9010\u6b65<\/span>\u5f00\u5c55<\/span>\u7684\u4e34\u5e8a<\/span>\u8bd5<\/span>\u9a8c\u7814<\/span>\u53d1<\/span>\u6a21\u5f0f<\/span>\u3002<\/span>\u6574\u4e2a \u4e34\u5e8a\u7814<\/span>\u53d1<\/span>\u8ba1\u5212<\/span>\u8981<\/span>\u8bbe\u5b9a<\/span>\u660e<\/span>\u786e\u7684<\/span>\u7ec8<\/span>\u6781\u76ee<\/span>\u6807\u4e0e<\/span>\u6e05\u6670\u7684<\/span>\u9012<\/span>\u8fdb\u7814<\/span>\u7a76<\/span>\u8def\u5f84<\/span>\uff1b<\/span>\u6bcf\u4e2a \u5177\u4f53\u7684<\/span>\u4e34<\/span>\u5e8a\u8bd5<\/span>\u9a8c<\/span>\u5e94\u6709<\/span>\u524d<\/span>\u671f\u7814<\/span>\u7a76<\/span>\u7684\u57fa<\/span>\u7840\uff0c<\/span>\u5e76\u8bbe\u5b9a<\/span>\u51c6<\/span>\u786e\u7684<\/span>\u8bd5<\/span>\u9a8c\u76ee<\/span>\u7684<\/span>\u3002\u540c \u65f6\uff0c\u6574<\/span>\u4f53<\/span>\u7814\u7a76<\/span>\u8bbe<\/span>\u8ba1\u5e94<\/span>\u80fd<\/span>\u652f\u6301<\/span>\u5bf9<\/span>\u7814\u7a76<\/span>\u836f\u7269<\/span>\u7684\u83b7<\/span>\u76ca<\/span>\/<\/span>\u98ce\u9669\u8bc4<\/span>\u4f30<\/span>\u3002<\/span><\/p>\n


<\/span><\/p>\n

2.2  \u8fdb\u5165\u4e34\u5e8a\u8bd5\u9a8c\u7684\u524d\u63d0<\/span><\/strong><\/p>\n

 \u65b0\u836f\u5728\u8fdb\u884c\u9996\u6b21\u4eba\u4f53\u8bd5\u9a8c\u524d\uff0c\u5e94\u5b8c\u6210\u5145\u5206\u7684\u975e\u4e34\u5e8a\u836f\u4ee3\u52a8\u529b<\/span>\u5b66\u3001\u836f<\/span>\u7406<\/span>\u5b66\u548c<\/span>\u6bd2<\/span>\u7406\u5b66<\/span>\u7814<\/span>\u7a76\uff0c<\/span>\u4ee5<\/span>\u9884\u6d4b<\/span>\u53ef\u80fd<\/span>\u7684\u4e34\u5e8a<\/span>\u6709<\/span>\u6548\u5242<\/span>\u91cf<\/span>\uff0c\u5e76<\/span>\u63d0<\/span>\u4f9b\u5145 \u5206\u7684\u4fe1<\/span>\u606f<\/span>\u6765\u652f<\/span>\u6301<\/span>\u9996\u6b21<\/span>\u4eba<\/span>\u4f53\u5242<\/span>\u91cf<\/span>\u7684\u9009<\/span>\u62e9\u548c<\/span>\u5b89\u5168\u7684<\/span>\u66b4<\/span>\u9732\u6301<\/span>\u7eed<\/span>\u65f6\u95f4<\/span>\uff0c<\/span>\u4ee5\u5145 \u5206\u4fdd\u969c<\/span>\u53d7<\/span>\u8bd5\u8005<\/span>\u7684<\/span>\u5b89\u5168\u3002<\/span><\/p>\n

 <\/span><\/p>\n

 <\/span>\u5efa\u8bae\u8fdb<\/span>\u884c<\/span>\u76f8<\/span>\u5173<\/span>\u7684<\/span>\u4f53\u5916<\/span>\u836f<\/span>\u7406\u8bd5<\/span>\u9a8c<\/span>\uff0c\u5bf9<\/span>\u836f\u7269<\/span>\u4e0e\u9776\u70b9<\/span>\u7684<\/span>\u76f8\u4e92<\/span>\u4f5c<\/span>\u7528\u53ca\u4f5c\u7528\u673a\u7406<\/span>\u6709<\/span>\u5145\u5206<\/span>\u7406<\/span>\u89e3\u3002<\/span>\u6bd4<\/span>\u5982<\/span>\u6297<\/span>VEG<\/span>F\u836f<\/span>\u7269<\/span>\u4e0e\u5176\u4f5c<\/span>\u7528<\/span>\u9776\u70b9<\/span>\u7ed3<\/span>\u5408\u7684<\/span>\u4eb2<\/span>\u548c\u529b\u4e0e \u6548\u80fd\u7b49<\/span>\u53c2<\/span>\u6570\u3002<\/span>\u6b64<\/span>\u5916\uff0c<\/span>\u5c3d<\/span>\u53ef\u80fd<\/span>\u91c7<\/span>\u7528\u52a8<\/span>\u7269\u75be<\/span>\u75c5\u6a21\u578b<\/span>\u5bf9<\/span>\u836f\u7269<\/span>\u8fdb<\/span>\u884c\u4e34<\/span>\u5e8a<\/span>\u524d\u836f \u7406\u5b9e\u9a8c<\/span>\u3002<\/span>\u4f46\u662f<\/span>\uff0c<\/span>\u7531\u4e8e<\/span>\u76ee<\/span>\u524d<\/span>AMD<\/span>\u5c1a<\/span>\u7f3a<\/span>\u4e4f<\/span>\u4e34<\/span>\u5e8a\u76f4\u63a5<\/span>\u76f8<\/span>\u5173\u7684<\/span>\u52a8<\/span>\u7269\u75be<\/span>\u75c5<\/span>\u6a21 \u578b\uff0c\u56e0<\/span>\u6b64<\/span>\u4ece\u4e34<\/span>\u5e8a<\/span>\u524d\u52a8<\/span>\u7269<\/span>\u836f\u7406<\/span>\u6570<\/span>\u636e\u5916<\/span>\u63a8\u81f3<\/span>\u4eba\u4f53\uff0c<\/span>\u53ca<\/span>\u9884\u6d4b<\/span>\u4eba<\/span>\u4f53\u7684<\/span>\u6709<\/span>\u6548\u5242 \u91cf\u9700\u8c28<\/span>\u614e<\/span>\u3002<\/span><\/p>\n


<\/p>\n

\u5bf9\u4e8e\u773c\u5c40\u90e8\u7ed9\u836f\uff08\u4f8b\u5982\uff1a\u73bb\u7483\u4f53\u5185\u6ce8\u5c04\u7ed9\u836f\uff09\u7684\u836f\u7269\uff0c\u9700\u8bc4\u4f30<\/span>\u836f\u7269\u5c40<\/span>\u90e8<\/span>\u66b4\u9732<\/span>\u548c<\/span>\u7cfb\u7edf<\/span>\u66b4<\/span>\u9732\u4e24<\/span>\u79cd<\/span>\u60c5\u51b5<\/span>\u3002<\/span>\u5bf9<\/span>\u4e8e\u5b58\u5728<\/span>\u5168<\/span>\u8eab\u66b4<\/span>\u9732<\/span>\u7684\u60c5<\/span>\u51b5<\/span>\u6216\u8005\u901a\u8fc7\u7cfb<\/span>\u7edf<\/span>\u9014\u5f84<\/span>\u7ed9<\/span>\u836f\u7684<\/span>\u836f<\/span>\u7269\uff0c<\/span>\u53ef<\/span>\u53c2\u8003<\/span>\u5e38\u89c4<\/span>\u7684\u7cfb\u7edf<\/span>\u836f<\/span>\u4ee3\u52a8<\/span>\u529b<\/span>\u5b66\u7684<\/span>\u7814<\/span>\u7a76\u65b9 \u6cd5\uff0c\u63d0<\/span>\u4f9b<\/span>\u8be5\u836f<\/span>\u7269<\/span>\u7684\u7cfb<\/span>\u7edf<\/span>\u66b4\u9732<\/span>\u60c5<\/span>\u51b5\u4ee5<\/span>\u53ca\u836f<\/span>\u7269\u4ee3\u8c22<\/span>\u3001<\/span>\u6d88\u9664<\/span>\u7b49<\/span>\u65f6\u95f4<\/span>\u52a8<\/span>\u529b\u5b66 \u8fc7\u7a0b\u7684<\/span>\u6570<\/span>\u636e\u3002<\/span>\u5bf9<\/span>\u4e8e\u4e3b<\/span>\u8981<\/span>\u5206\u5e03<\/span>\u5728<\/span>\u773c\u5c40<\/span>\u90e8\u7684<\/span>\u836f\u7269\uff0c<\/span>\u5efa<\/span>\u8bae\u63d0<\/span>\u4f9b<\/span>\u76f8\u5173<\/span>\u7684<\/span>\u52a8\u7269 \u773c\u5c40\u90e8<\/span>\u836f<\/span>\u7269\u4ee3<\/span>\u8c22<\/span>\u52a8\u529b<\/span>\u5b66<\/span>\u7684\u6570<\/span>\u636e<\/span>\uff0c<\/span>\u5305<\/span>\u62ec<\/span>\u836f<\/span>\u7269<\/span>\u5728<\/span>\u623f<\/span>\u6c34<\/span>\u3001\u73bb<\/span>\u7483<\/span>\u4f53<\/span>\u6db2<\/span>\u7b49<\/span>\u7684\u5206 \u5e03\u3001\u4ee3<\/span>\u8c22<\/span>\u548c\u6d88<\/span>\u9664<\/span>\u8fc7<\/span>\u7a0b<\/span>\u3002<\/span>\u9f13\u52b1<\/span>\u65b0<\/span>\u65b9\u6cd5<\/span>\u548c\u65b0<\/span>\u6280\u672f\u7684<\/span>\u5e94<\/span>\u7528\uff0c<\/span>\u5305<\/span>\u62ec\u6838<\/span>\u7d20<\/span>\u5206\u5b50\u5f71\u50cf\u6280<\/span>\u672f<\/span>\u4ee5\u53ca<\/span>\u836f<\/span>\u4ee3\u52a8<\/span>\u529b<\/span>\u5b66\u6a21<\/span>\u578b<\/span>\/<\/span>\u6a21\u62df<\/span>\u6280\u672f<\/span>\u7b49\u3002\u540c<\/span>\u65f6<\/span>\uff0c\u5728<\/span>\u52a8<\/span>\u7269\u75be<\/span>\u75c5<\/span>\u6a21\u578b \u4e2d\u5e94\u5c3d<\/span>\u53ef<\/span>\u80fd\u540c<\/span>\u65f6<\/span>\u89c2\u5bdf<\/span>\u836f<\/span>\u4ee3\u3001<\/span>\u836f<\/span>\u6548\u3001<\/span>\u6bd2\u6027<\/span>\u7684\u76f8\u5173<\/span>\u6027<\/span>\u7814\u7a76<\/span>\u3002<\/span>\u901a\u8fc7<\/span>\u5c40<\/span>\u90e8\u7ed9 \u836f\u540e\u89c2<\/span>\u5bdf<\/span>\u5230\u7684<\/span>\u91cd<\/span>\u8981\u7684<\/span>\u4e34<\/span>\u5e8a\u7597<\/span>\u6548<\/span>\u548c<\/span>\/<\/span>\u6216<\/span>\u8005\u5b89<\/span>\u5168\u6027\u6307<\/span>\u6807<\/span>\u7684\u65f6<\/span>\u95f4<\/span>\u52a8\u6001<\/span>\u8fc7<\/span>\u7a0b\u6765\u8bc4\u4ef7\u836f<\/span>\u7269<\/span>\u53ef\u80fd<\/span>\u7684<\/span>\u5c40<\/span>\u90e8<\/span>\u66b4<\/span>\u9732\u4e0e<\/span>\u836f<\/span>\u6548\u6216<\/span>\u8005\u5b89<\/span>\u5168\u6027\u4e4b<\/span>\u95f4<\/span>\u7684\u5173<\/span>\u7cfb<\/span>\u3002<\/span><\/p>\n

 <\/span> <\/span><\/p>\n

\u5728\u6b63\u5f0f\u542f\u52a8\u4e34\u5e8a\u8bd5\u9a8c\u524d\uff0c\u5e94\u5bf9\u836f\u7269\u7684\u5206\u5e03\u548c\u9776\u70b9\u7ed3\u5408\u7684\u60c5\u51b5\u8fdb\u884c\u7814\u7a76\uff0c\u91cd\u70b9\u5173\u6ce8\u5c40\u90e8\u7528\u836f\u7684\u5168\u8eab\u66b4\u9732\u548c\u975e\u9776\u5668\u5b98\u7684\u5206\u5e03\u548c\u84c4\u79ef\uff0c \u4ee5\u53ca\u5168\u8eab\u7528\u836f\u540e\u836f\u7269\u5728\u773c\u90e8\u7684\u5206\u5e03\u548c\u9776\u70b9\u7ed3\u5408\u60c5\u51b5\u7b49\u3002<\/span><\/p>\n

 <\/span><\/p>\n

2.3  \u4e34\u5e8a\u836f\u7406\u5b66\u7814\u7a76<\/span><\/strong><\/p>\n

2.3.1  \u9996\u6b21\u4eba\u4f53\u8bd5\u9a8c <\/span><\/strong><\/p>\n

\u57fa\u4e8e\u4f26\u7406\u5b66\u3001\u836f\u7269\u975e\u4e34\u5e8a\u83b7\u76ca\/\u98ce\u9669\u6743\u8861\u7684\u8003\u8651\uff0c\u5bf9\u4e8e\u73bb\u7483\u4f53\u5185<\/span>\u6ce8\u5c04\u7ed9<\/span>\u836f<\/span>\uff0c<\/span>AMD<\/span>\u60a3<\/span>\u8005<\/span>\u53ef\u4f5c<\/span>\u4e3a<\/span>\u65e9\u671f<\/span>\u63a2<\/span>\u7d22<\/span>\u6027<\/span>\u4e34\u5e8a\u8bd5<\/span>\u9a8c<\/span>\u7684\u9996<\/span>\u9009<\/span>\u4eba\u7fa4<\/span>\uff1b<\/span>\u5bf9\u4e8e \u5c40\u90e8\u6ef4<\/span>\u773c<\/span>\u6db2\u3001<\/span>\u53e3<\/span>\u670d\u7ed9<\/span>\u836f<\/span>\u3001\u9759<\/span>\u8109<\/span>\u7ed9\u836f<\/span>\u7684\u836f<\/span>\u7269\uff0c\u6839<\/span>\u636e<\/span>\u836f\u7269<\/span>\u7279<\/span>\u70b9\uff0c<\/span>\u53ef<\/span>\u9009\u5065 \u5eb7\u53d7\u8bd5<\/span>\u8005<\/span>\u6216<\/span>AMD<\/span>\u60a3<\/span>\u8005<\/span>\uff0c\u9075<\/span>\u5faa<\/span>\u4e00\u822c<\/span>\u6307<\/span>\u5357\u3002<\/span><\/p>\n


<\/span><\/p>\n

\u9996\u6b21\u4eba\u4f53\u8bd5\u9a8c\u7684\u4e3b\u8981\u7814\u7a76\u7ec8\u70b9\u4e3a\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u8003\u5bdf\uff0c\u5173\u6ce8\u773c\u5c40<\/span>\u90e8\u548c\u5168<\/span>\u8eab<\/span>\u5b89\u5168<\/span>\u6027<\/span>\u3002<\/span>\u5e94<\/span>\u8fdb\u884c<\/span>\u5355<\/span>\u5242\u91cf<\/span>\u548c<\/span>\u591a<\/span>\u5242<\/span>\u91cf\u7ed9\u836f<\/span>\u540e<\/span>\u4eba\u4f53<\/span>\u5b89<\/span>\u5168\u8010<\/span>\u53d7<\/span>\u6027\u8003\u5bdf\u3002\u5bf9\u4e8e\u5355<\/span>\u6297<\/span>\u7c7b\u836f<\/span>\u7269<\/span>\u6216<\/span>\u8005<\/span>\u878d<\/span>\u5408\u6027<\/span>\u86cb<\/span>\u767d<\/span>\u7b49<\/span>\u751f\u7269<\/span>\u5236\u54c1<\/span>\uff0c<\/span>\u8fd8\u9700<\/span>\u540c<\/span>\u65f6\u8003<\/span>\u5bdf<\/span>\u5176\u514d<\/span>\u75ab<\/span>\u539f\u6027\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u9996\u6b21\u4eba\u4f53\u8bd5\u9a8c\u5e94\u57fa\u4e8e\u975e\u4e34\u5e8a\u5b89\u5168\u6027\u4fe1\u606f\uff0c\u91c7\u7528\u5408\u9002\u7684\u5242\u91cf\u9012\u589e\u65b9\u6848\uff0c\u5bf9\u4e0d\u540c\u5242\u91cf\u6c34\u5e73\u8fdb\u884c\u7814\u7a76\uff0c\u4ee5\u63d0\u4f9b\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u524d\u671f\u6570\u636e\uff0c\u5e76\u5c3d\u53ef\u80fd\u63a2\u8ba8\u6700\u5927\u8010\u53d7\u5242\u91cf<\/span><\/p>\n

 <\/span> <\/span><\/p>\n

\u5404\u79cd\u7ed9\u836f\u9014\u5f84\u7684\u836f\u7269\uff0c\u5c24\u5176\u662f\u73bb\u7483\u4f53\u6ce8\u5c04\u7684\u836f\u7269\uff0c\u5728\u5f00\u5c55\u9996\u6b21\u4eba\u4f53\u8bd5\u9a8c\u65f6\uff0c\u5e94\u5168\u9762\u89c2\u5bdf\u773c\u5c40\u90e8\u548c\u5168\u8eab\u5b89\u5168\u6027\uff0c\u5305\u62ec\u4e0d\u826f\u4e8b\u4ef6\u3001\u7cfb\u7edf\u773c \u79d1\u68c0\u67e5\u7b49\uff08\u8be6\u89c13.7\u90e8\u5206\uff09\u3002\u5c40\u90e8\u4e0d\u826f\u53cd\u5e94\u9700\u5173\u6ce8\u836f\u7269\u76f8\u5173\u548c\u7ed9\u836f\u65b9 \u5f0f\u76f8\u5173\u7684\u4e0d\u826f\u53cd\u5e94\u3002<\/span><\/p>\n


<\/span><\/p>\n

2.3.2  \u836f\u4ee3\u52a8\u529b\u5b66\u548c\u836f\u6548\u52a8\u529b\u5b66\u7814\u7a76<\/span><\/strong><\/p>\n

\u5728\u65e9\u671f\u63a2\u7d22\u6027\u7814\u7a76\u4e2d\uff0c\u5e94\u5c3d\u53ef\u80fd\u5f00\u5c55\u5168\u9762\u7684\u836f\u4ee3\u52a8\u529b\u5b66\uff08PK\uff09\u548c<\/span>\u836f\u6548<\/span>\u5b66<\/span>\uff08<\/span>PD<\/span>\uff09<\/span>\u7814\u7a76<\/span>\u3002<\/span>\u4e0d\u8bba<\/span>\u662f<\/span>\u7cfb\u7edf<\/span>\u6216<\/span>\u773c<\/span>\u5c40<\/span>\u90e8\u7528\u836f<\/span>\uff0c<\/span>\u90fd\u9700<\/span>\u6839<\/span>\u636e\u836f<\/span>\u7269<\/span>\u7684\u5b9e\u9645 \u5206\u5e03\u60c5<\/span>\u51b5<\/span>\u5f00\u5c55<\/span>\u76f8<\/span>\u5e94\u7684<\/span>\u836f<\/span>\u4ee3\u52a8<\/span>\u529b<\/span>\u5b66\u7814<\/span>\u7a76<\/span>\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u9274\u4e8e\u623f\u6c34\u3001\u73bb\u7483\u4f53\u4e0e\u89c6\u7f51\u819c\u7d27\u5bc6\u9760\u8fd1\u5e76\u90bb\u63a5\uff0c\u623f\u6c34\u548c\u73bb\u7483\u4f53\u6db2 \u53ef\u8f83\u8840\u6db2\u66f4\u597d\u5730\u53cd\u5e94\u89c6\u7f51\u819c\u7684\u53d8\u5316\uff0c\u56e0\u6b64\uff0c\u623f\u6c34\u548c\u73bb\u7483\u4f53\u91c7\u6837\u6709\u52a9\u4e8e\u4e86\u89e3\u773c\u90e8\u836f\u4ee3\u52a8\u529b\u5b66\u3001\u836f\u7269\u9776\u70b9\u4f5c\u7528\uff08VEGF\u6291\u5236\uff09\u548c\u4e34\u5e8a\u7597\u6548\u6301\u7eed\u65f6\u95f4\u4e4b\u95f4\u7684\u5173\u7cfb\u3002\u4f46\uff0c\u57fa\u4e8e\u4f26\u7406\u8003\u8651\uff0c\u96be\u4ee5\u91c7\u96c6\u8db3\u91cf\u7684\u73bb\u7483\u4f53\u6216\u623f\u6c34\u7b49\u773c\u5c40\u90e8\u7ec4\u7ec7\u6db2\u8fdb\u884c\u773c\u5c40\u90e8\u836f\u4ee3\u52a8\u529b\u5b66\u7814\u7a76\uff0c\u5bf9\u6b64\uff0c\u5efa\u8bae\u5c3d\u53ef<\/span>\u80fd\u9009\u62e9<\/span>\u9002<\/span>\u5b9c\u53d6<\/span>\u6837<\/span>\u7684\u60a3<\/span>\u8005<\/span>\uff08\u5982<\/span>\u62df<\/span>\u884c\u73bb<\/span>\u7483\u4f53<\/span>\u5207\u9664\u7684<\/span>\u60a3<\/span>\u8005<\/span>\u7b49<\/span>\uff09<\/span>\uff0c\u5728<\/span>\u786e<\/span>\u4fdd<\/span>\u60a3<\/span>\u8005\u5b89\u5168<\/span>\u4e14<\/span>\u60a3\u8005<\/span>\u77e5<\/span>\u60c5\u540c<\/span>\u610f<\/span>\u7684\u60c5<\/span>\u51b5<\/span>\u4e0b\u8fdb<\/span>\u884c\u7a00<\/span>\u758f\u91c7<\/span>\u6837<\/span>\uff0c<\/span>\u4ee5\u8fdb<\/span>\u884c<\/span>\u5c40\u90e8<\/span>\u836f<\/span>\u4ee3\u52a8\u529b\u5b66\u7814<\/span>\u7a76<\/span>\u3002\u540c<\/span>\u65f6<\/span>\uff0c\u4e5f<\/span>\u9f13<\/span>\u52b1\u7533<\/span>\u529e<\/span>\u8005\u91c7<\/span>\u7528\u65e0<\/span>\u521b<\/span>\u7684\u5148<\/span>\u8fdb<\/span>\u65b9\u6cd5<\/span>\u5728<\/span>\u786e\u4fdd<\/span>\u60a3<\/span>\u8005\u5b89\u5168\u7684\u524d<\/span>\u63d0<\/span>\u4e0b\u63a2<\/span>\u7d22<\/span>\u773c\u5c40<\/span>\u90e8<\/span>\u836f\u4ee3<\/span>\u548c<\/span>\/<\/span>\u6216\u836f<\/span>\u6548\u60c5<\/span>\u51b5\u3002\u9f13<\/span>\u52b1<\/span>\u7533\u529e<\/span>\u8005<\/span>\u5efa\u7acb<\/span>\u9002<\/span>\u5f53\u7684 \u6570\u5b66\u6a21<\/span>\u578b<\/span>\uff0c\u901a<\/span>\u8fc7<\/span>\u52a8\u7269<\/span>\u8bd5<\/span>\u9a8c\u6570<\/span>\u636e<\/span>\u548c<\/span>\/<\/span>\u6216<\/span>\u4eba\u4f53<\/span>\u7a00\u758f\u91c7<\/span>\u6837<\/span>\u7814\u7a76<\/span>\u6570<\/span>\u636e\u5916<\/span>\u63a8<\/span>\u4eba\u4f53\u773c\u5c40\u90e8<\/span>\u7684<\/span>\u836f\u4ee3<\/span>\u52a8<\/span>\u529b\u5b66<\/span>\u53c2<\/span>\u6570\u5e76<\/span>\u8fdb<\/span>\u4e00\u6b65<\/span>\u63a2\u8ba8<\/span>\u836f\u7269\u7684<\/span>\u5c40<\/span>\u90e8\u66b4<\/span>\u9732<\/span>\u4e0e\u4e34<\/span>\u5e8a<\/span>\u7597\u6548 \u548c\u5b89\u5168<\/span>\u6027<\/span>\u7684\u5173<\/span>\u7cfb<\/span>\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u68c0\u6d4b\u836f\u6548\u5b66\u548c\u5b89\u5168\u6027\u751f\u7269\u6807\u5fd7\u7269\u6709\u52a9\u4e8e\u786e\u8ba4\u836f\u7269\u5c40\u90e8\u66b4\u9732\u4ee5\u53ca \u4e0e\u76f8\u5173\u836f\u6548\u5b66\/\u5b89\u5168\u6027\u6807\u8bb0\u7269\u7684\u76f8\u5173\u6027\u3002\u5176\u4e2d\uff0c\u836f\u6548\u5b66\u751f\u7269\u6807\u5fd7\u7269\u5e94\u57fa\u4e8e\u5bf9\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\u53d1\u75c5\u673a\u5236\u7684\u4e86\u89e3\u548c\u836f\u7269\u4f5c\u7528\u673a\u5236\u7279\u70b9\u8fdb\u884c\u9009\u62e9\uff0c\u5305\u62ec\u6d4b\u5b9a\u4e0d\u540c\u65f6\u95f4\u70b9\u4f53\u5faa\u73af\u548c\/\u6216\u623f\u6c34\u3001\u73bb\u7483\u4f53\u4e2d\u6e38\u79bb\u5206\u5b50 \u9776\u70b9\uff08\u5982\u6e38\u79bbVEGF\u7b49\uff09\u6d53\u5ea6\uff0c\u5c3d\u53ef\u80fd\u63a2\u8ba8\u773c\u5c40\u90e8\u6709\u5173\u8840\u7ba1\u751f\u6210\uff08\u5305 \u62ec\u4f46\u4e0d\u9650\u4e8eVEGF\uff0cVEGF-\u53d7\u4f53\u3001\u8840\u5c0f\u677f\u6e90\u751f\u957f\u56e0\u5b50\u7b49\uff09\u548c\u708e\u75c7\uff08\u5305 \u62ec\u4f46\u4e0d\u9650\u4e8eIL-1b\u3001IL-6\u53ca\u81ea\u5206\u6ccc\u8fd0\u52a8\u56e0\u5b50\uff09\u7b49\u76f8\u5173\u7684\u751f\u7269\u6807\u5fd7\u7269\uff0c\u4ee5\u66f4\u597d\u4e86\u89e3\u60a3\u8005\u5bf9\u836f\u7269\u53cd\u5e94\u7684\u53d8\u5316\u53ca\u5176\u539f\u56e0\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u5bf9\u4e8e\u773c\u5c40\u90e8\u7ed9\u836f\uff0c\u6e38\u79bb\u836f\u7269\u7684\u5168\u8eab\u66b4\u9732\u53ef\u80fd\u5f71\u54cd\u6216\u5e72\u6270\u91cd\u8981\u7684\u7cfb\u7edf\u4fe1\u53f7\u901a\u8def\uff0c\u4ece\u800c\u4ea7\u751f\u4e25\u91cd\u7684\u5168\u8eab\u6027\u4e0d\u826f\u53cd\u5e94\uff0c\u6545\u5e94\u8fdb\u884c\u5168\u8eab\u836f \u4ee3\u52a8\u529b\u5b66\u7814\u7a76\uff0c\u6839\u636e\u836f\u7269\u7684\u5438\u6536\u3001\u5206\u5e03\u3001\u4ee3\u8c22\u3001\u6d88\u9664\u7279\u5f81\uff0c\u5408\u7406\u8bbe \u8ba1\u91c7\u6837\u65f6\u95f4\uff0c\u5c3d\u53ef\u80fd\u5efa\u7acb\u7cfb\u7edf\u66b4\u9732\u91cf\u4e0e\u5168\u8eab\u76f8\u5173\u4e0d\u826f\u53cd\u5e94\u7684\u5173\u7cfb\u3002\u540c\u65f6\uff0c\u5e94\u5173\u6ce8\u8840\u6db2\u4e2d\u6e38\u79bb\u836f\u7269\u3001\u86cb\u767d\u7ed3\u5408\u836f\u7269\u3001\u836f\u7269-\u53d7\u4f53\u7ed3\u5408\u7269\u3001<\/span>\u6297\u836f\u6297<\/span>\u4f53<\/span>\u4ee5\u53ca<\/span>\u4e2d<\/span>\u548c\u6297<\/span>\u4f53<\/span>\u6d53\u5ea6<\/span>\u53d8<\/span>\u5316<\/span>\u7279<\/span>\u5f81\uff0c<\/span>\u4ee5\u53ca\u8840<\/span>\u773c<\/span>\u5c4f\u969c<\/span>\u5bf9<\/span>\u4e0d\u540c<\/span>\u4e2a<\/span>\u4f53\u95f4<\/span>\u836f\u7269\u5438<\/span>\u6536<\/span>\u53d8\u5f02<\/span>\u5ea6<\/span>\u5f71\u54cd\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u7531\u4e8e\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\u591a\u53d1\u4e8e50\u5c81\u4ee5\u4e0a\u60a3\u8005\uff0c\u6545\u5e94\u57fa\u4e8e\u836f\u7269 \u7684\u4ee3\u8c22\u6d88\u9664\u65b9\u5f0f\uff0c\u5f00\u5c55\u8001\u5e74\u4eba\u3001\u809d\u3001\u80be\u529f\u80fd\u4e0d\u5168\u53d7\u8bd5\u8005\u7684\u7cfb\u7edf\u836f\u4ee3\u52a8\u529b\u5b66\u7814\u7a76\uff0c\u5fc5\u8981\u65f6\uff0c\u5e94\u5728\u4e34\u5e8a\u8bd5\u9a8c\u8fc7\u7a0b\u4e2d\u8fdb\u884c\u5f00\u5c55\u7fa4\u4f53\u836f\u4ee3\u52a8\u529b\u5b66\u7814\u7a76\uff0c\u4ee5\u53ca\u76f8\u5e94\u7684\u5242\u91cf-\u66b4\u9732-\u6548\u5e94\u5173\u7cfb\u7814\u7a76\uff0c\u4ee5\u4e86\u89e3\u5f71\u54cd\u836f\u7269\u836f\u4ee3\u52a8\u529b \u5b66\u7279\u5f81\u3001\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\u7684\u5185\u5728\u56e0\u7d20\uff0c\u4ee5\u53ca\u76f8\u5e94\u4eba\u7fa4\u7684\u5242\u91cf\u8c03\u6574\u3002<\/span> <\/span><\/p>\n

 <\/span><\/p>\n

AMD\u60a3\u8005\u591a\u53d1\u4e8e\u8001\u5e74\u60a3\u8005\uff0c\u6545\u9700\u8003\u8651\u5f00\u5c55\u4e0e\u7cd6\u5c3f\u75c5\u3001\u9ad8\u8840\u538b\u7b49\u8001\u5e74\u5e38\u89c1\u75be\u75c5\u6cbb\u7597\u836f\u7269\u7684\u6f5c\u5728\u76f8\u4e92\u4f5c\u7528\u7814\u7a76\u3002<\/span><\/p>\n

 <\/span><\/p>\n

2.4\u63a2\u7d22\u6027\u4e34\u5e8a\u8bd5\u9a8c<\/span><\/strong><\/p>\n

\u5728\u65e9\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u5e94\u5f00\u5c55\u63a2\u7d22\u6027\u7814\u7a76\uff0c\u83b7\u5f97\u5173\u4e8e\u836f\u7269\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u7684\u521d\u6b65\u4fe1\u606f\uff0c\u4ee5\u786e\u5b9a\u662f\u5426\u63a8\u8fdb\u5230\u786e\u8bc1\u6027\u8bd5\u9a8c\u3002\u63a2\u7d22\u6027\u7814\u7a76\u53ef \u9488\u5bf9\u4e0d\u540c\u7684\u4eba\u7fa4\u3001\u7ed9\u836f\u65b9\u5f0f\u3001\u5242\u91cf\u3001\u7597\u7a0b\u3001\u8bc4\u4ef7\u6307\u6807\u7b49\u65b9\u9762\u5f00\u5c55\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u63a2\u7d22\u6027\u4e34\u5e8a\u8bd5\u9a8c\u8bbe\u8ba1\u5e94\u57fa\u4e8e\u65e9\u671f\u4e34\u5e8a\u836f\u7406\u5b66\u7814\u7a76\u7ed3\u679c\uff0c\u660e\u786e\u5242\u91cf\u8010\u53d7\u8303\u56f4\u4e4b\u540e\uff0c\u8bbe\u8ba1\u5242\u91cf\u63a2\u7d22\u8bd5\u9a8c\uff0c\u4ee5\u786e\u7acb\u4e34\u5e8a\u7597\u6548\u4e0e\u5242\u91cf\u95f4\u7684\u53cd\u5e94\u5173\u7cfb\u3002\u5efa\u8bae\u91c7\u7528\u4e34\u5e8a\u6709\u6548\u6027\u6307\u6807\u8fdb\u884c\u8bc4\u4ef7\uff0c\u5305\u62ec\u529f\u80fd\u5b66\u6307\u6807\u548c\u5f62\u6001\u5b66\u6307\u6807\uff08\u8be6\u89c13.6.1\uff09\u3002\u5efa\u8bae\u540c\u65f6\u91c7\u7528\u80fd\u591f\u53cd\u6620\u75be\u75c5\u75c5\u7a0b\u6216\u75c5\u60c5 \u4e25\u91cd\u7a0b\u5ea6\u7684\u751f\u7269\u6807\u5fd7\u7269\u3001\u836f\u6548\u5b66\u6307\u6807\u8fdb\u884c\u63a2\u7d22\u7814\u7a76\u9636\u6bb5\u7684\u6709\u6548\u6027\u8bc4 \u4ef7\u3002<\/span><\/p>\n

\u5242\u91cf\u63a2<\/span>\u7d22<\/span>\u8bd5\u9a8c<\/span>\u7684<\/span>\u5468\u671f<\/span>\u5e94<\/span>\u6839\u636e<\/span>\u63a2<\/span>\u7d22\u8bd5<\/span>\u9a8c\u7684<\/span>\u76ee\u7684\u8fdb<\/span>\u884c<\/span>\u8bbe\u8ba1<\/span>\u3002<\/span>\u91cd\u8981\u7684<\/span>\u8003\u8651\u56e0<\/span>\u7d20<\/span>\u5305\u62ec<\/span>\uff0c<\/span>\u4f46\u4e0d<\/span>\u9650<\/span>\u4e8e\uff1a<\/span>\u89c2<\/span>\u5bdf\u8fbe<\/span>\u5230\u836f<\/span>\u7269\u8d77\u6548<\/span>\u548c<\/span>\u6301\u7eed<\/span>\u4f5c<\/span>\u7528\u6240<\/span>\u9700<\/span>\u7684\u65f6 \u95f4\u3001\u60a3<\/span>\u8005<\/span>\u4eba\u7fa4<\/span>\u3001<\/span>\u5bf9\u7167<\/span>\u836f<\/span>\u7269\u7684<\/span>\u9009<\/span>\u62e9\u3001<\/span>\u8bd5\u9a8c<\/span>\u836f\u7269\u4e0d<\/span>\u540c<\/span>\u5242\u91cf<\/span>\u7ec4<\/span>\u4e4b\u95f4<\/span>\u6709<\/span>\u6548\u6027 \u4e0e\u5b89\u5168<\/span>\u6027<\/span>\u7684\u5dee<\/span>\u522b<\/span>\u7b49\u3002<\/span><\/p>\n

 <\/span> <\/span><\/p>\n

2.5  \u786e\u8bc1\u6027\u4e34\u5e8a\u8bd5\u9a8c<\/span><\/strong><\/p>\n

\u5728\u4e34\u5e8a\u836f\u7406\u5b66\u3001\u63a2\u7d22\u6027\u4e34\u5e8a\u8bd5\u9a8c\u57fa\u7840\u4e0a\uff0c\u5f00\u5c55\u8fdb\u4e00\u6b65\u786e\u8bc1\u6027\u4e34 \u5e8a\u8bd5\u9a8c\u4ee5\u652f\u6301\u4ea7\u54c1\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\uff0c\u8bc4\u4ef7\u60a3\u8005\u7684\u4e34\u5e8a\u6709\u6548\u6027\u548c\u5b89 \u5168\u6027\uff0c\u5e76\u7528\u4e8e\u652f\u6301\u83b7\u76ca\/\u98ce\u9669\u8bc4\u4f30\u3002\u786e\u8bc1\u6027\u4e34\u5e8a\u8bd5\u9a8c\u5e94\u5bf9\u8bd5\u9a8c\u836f\u7269\u7684 \u7597\u6548\u8fdb\u884c\u51c6\u786e\u7684\u4f30\u8ba1\u3002\u836f\u7269\u7597\u6548\u7684\u8bf4\u660e\u65e2\u8981\u8bc1\u660e\u4e3b\u8981\u5047\u8bbe\u7684\u7edf\u8ba1\u5b66 \u610f\u4e49\uff0c\u8fd8\u8981\u8bc4\u4f30\u7597\u6548\u5177\u6709\u4e34\u5e8a\u610f\u4e49\u3002<\/span><\/p>\n


<\/p>\n

3\uff0e \u4e34\u5e8a\u8bd5\u9a8c\u8bbe\u8ba1\u7684\u8003\u8651<\/span><\/strong><\/p>\n

3.1\u603b\u4f53\u8bbe\u8ba1\u8003\u8651<\/span><\/strong><\/p>\n

\u4e34\u5e8a\u8bd5\u9a8c\u7684\u603b\u4f53\u8bbe\u8ba1\u5e94\u6839\u636e\u4e34\u5e8a\u8bd5\u9a8c\u7684\u4e0d\u540c\u9636\u6bb5\u3001\u7814\u7a76\u76ee\u7684\u3001<\/span>\u75be\u75c5\u7279<\/span>\u70b9<\/span>\u3001\u5b9e<\/span>\u65bd<\/span>\u7684\u53ef<\/span>\u884c<\/span>\u6027\uff0c<\/span>\u91c7<\/span>\u7528\u76f8<\/span>\u5e94\u7684<\/span>\u8bbe\u8ba1\u65b9<\/span>\u6848<\/span>\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u63a2\u7d22\u6027\u8bd5\u9a8c\u8bbe\u8ba1\u901a\u5e38\u53ef\u91c7\u7528\u76f8\u5bf9\u66f4\u4e3a\u7075\u6d3b\u7684\u8bbe\u8ba1\u3002\u786e\u8bc1\u6027\u4e34\u5e8a\u8bd5\u9a8c\u5219\u987b\u6709\u660e\u786e\u7684\u5047\u8bbe\u68c0\u9a8c\uff0c\u5e76\u83b7\u5f97\u6709\u6548\u6027\u8bc4\u4ef7\u7684\u7ed3\u8bba\u3002\u8bbe\u8ba1\u7c7b\u578b \u53ef\u4ee5\u662f\u4f18\u6548\u6027\u8bbe\u8ba1\u3001\u975e\u52a3\u6548\u6027\u6216\u7b49\u6548\u6027\u8bbe\u8ba1\uff0c\u4e5f\u53ef\u4ee5\u91c7\u7528\u5305\u62ec\u5b89\u6170 \u5242\u548c\u9633\u6027\u6cbb\u7597\u5bf9\u7167\u7684\u4e09\u81c2\u8bd5\u9a8c\u8bbe\u8ba1\u3002<\/span><\/p>\n

 <\/span><\/p>\n

3.2  \u53d7\u8bd5\u8005\u7684\u9009\u62e9<\/span><\/strong><\/p>\n

\u53d7\u8bd5\u4eba\u7fa4\u5e94\u80fd\u591f\u5145\u5206\u4ee3\u8868\u76ee\u6807\u9002\u5e94\u75c7\u4eba\u7fa4\u7684\u60a3\u8005\u7279\u5f81\u3002\u901a\u5e38\u8003<\/span>\u8651\u7684\u7279<\/span>\u5f81<\/span>\u5305\u62ec<\/span>\u4f46<\/span>\u4e0d\u9650<\/span>\u4e8e<\/span>\uff1a<\/span><\/p>\n

 <\/span><\/p>\n

\u6839\u636e\u7814<\/span>\u7a76<\/span>\u836f\u7269<\/span>\u7684<\/span>\u4f5c\u7528<\/span>\u673a<\/span>\u5236\u7279<\/span>\u70b9<\/span>\u53ca\u5df2<\/span>\u77e5<\/span>\u548c<\/span>\u6f5c\u5728\u5b89<\/span>\u5168<\/span>\u6027\u98ce<\/span>\u9669<\/span>\u7b49\uff0c\u9488\u5bf9\u6027\u9009<\/span>\u62e9<\/span>\u53d7\u8bd5<\/span>\u4eba<\/span>\u7fa4<\/span>\u3002<\/span>\u901a<\/span>\u5e38\u5305<\/span>\u62ec<\/span>\u4e00\u822c<\/span>\u5165<\/span>\u9009<\/span>\/<\/span>\u6392\u9664\u6807<\/span>\u51c6<\/span>\u548c\u7814<\/span>\u7a76<\/span>\u773c\u773c<\/span>\u90e8<\/span>\u5165<\/span>\u9009<\/span>\/ \u6392\u9664\u6807<\/span>\u51c6<\/span>\u3002\u4e00<\/span>\u822c<\/span>\u5165<\/span>\u9009<\/span>\/\u6392<\/span>\u9664\u6807<\/span>\u51c6<\/span>\u9700\u6839<\/span>\u636e\u76ee<\/span>\u6807\u4eba\u7fa4<\/span>\u7279<\/span>\u5f81\u660e<\/span>\u786e<\/span>\u60a3\u8005<\/span>\u5e74<\/span>\u9f84<\/span>\u8303\u56f4\u3001\u77e5<\/span>\u60c5<\/span>\u540c\u610f<\/span>\u3001<\/span>\u57fa\u7840<\/span>\u75be<\/span>\u75c5<\/span>\u548c<\/span>\u4f34<\/span>\u968f\u75be<\/span>\u75c5\u60c5<\/span>\u51b5<\/span>\u3001\u662f<\/span>\u5426<\/span>\u9700\u907f<\/span>\u5b55<\/span>\u3001\u65e2<\/span>\u5f80<\/span>\u6cbb\u7597 \u53f2\u3001\u662f<\/span>\u5426<\/span>\u6709\u4f34<\/span>\u968f<\/span>\u6cbb\u7597<\/span>\u7b49<\/span>\u6807\u51c6<\/span>\u3002<\/span>\u7814\u7a76<\/span>\u773c\u5165<\/span>\u9009<\/span>\/<\/span>\u6392<\/span>\u9664<\/span>\u6807<\/span>\u51c6<\/span>\u901a<\/span>\u5e38<\/span>\u9700\u4ece<\/span>\u529f<\/span>\u80fd\u5b66\u548c\u5f62\u6001<\/span>\u5b66<\/span>\u7684\u4e24<\/span>\u4e2a<\/span>\u65b9\u9762<\/span>\u8fdb<\/span>\u884c\u8bc4<\/span>\u4f30<\/span>\uff0c<\/span>\u5305<\/span>\u62ec\u6700<\/span>\u4f73\u77eb\u6b63<\/span>\u89c6<\/span>\u529b\uff0c<\/span>\u4e2d<\/span>\u5fc3\u89c6<\/span>\u7f51<\/span>\u819c\u539a\u5ea6\u3001\u75c5<\/span>\u7076<\/span>\u9762\u79ef<\/span>\u7b49<\/span>\uff08<\/span>\u8be6<\/span>\u89c1<\/span>3<\/span>.<\/span>6<\/span>\u7597<\/span>\u6548\u6307<\/span>\u6807<\/span>\u90e8<\/span>\u5206<\/span>\uff09<\/span>\u3002\u5165<\/span>\u9009<\/span>\u60a3\u8005<\/span>\u7684<\/span>\u89c6\u529f<\/span>\u80fd<\/span>\u635f\u4f24\u548c\u75c5\u53d8<\/span>\u5f62<\/span>\u6001<\/span>\u5b66<\/span>\u7684<\/span>\u4e25<\/span>\u91cd<\/span>\u7a0b<\/span>\u5ea6\uff0c<\/span>\u5e94<\/span>\u6839\u636e<\/span>\u7814\u7a76<\/span>\u836f\u7269\u7684<\/span>\u7279<\/span>\u70b9\u3001<\/span>\u76ee<\/span>\u6807\u53d7<\/span>\u8bd5<\/span>\u4eba\u7fa4\u3001\u4e0d<\/span>\u540c<\/span>\u8bd5\u9a8c<\/span>\u9636<\/span>\u6bb5<\/span>\u548c<\/span>\u76ee<\/span>\u7684\u7b49<\/span>\u56e0<\/span>\u7d20\u7efc<\/span>\u5408<\/span>\u8bc4<\/span>\u4f30<\/span>\u540e<\/span>\u8fdb<\/span>\u884c<\/span>\u8bbe\u8ba1<\/span>\u3002<\/span>\u9009\u62e9<\/span>\u8fdb<\/span>\u5c55\u671f<\/span>AMD\u4f5c<\/span>\u4e3a\u53d7<\/span>\u8bd5<\/span>\u4eba\u7fa4<\/span>\u65f6<\/span>\uff0c\u5e94<\/span>\u533a<\/span>\u5206<\/span>GA\u6216<\/span>n<\/span>A<\/span>MD<\/span>\u7b49\u3002<\/span><\/p>\n

 <\/span><\/p>\n

 <\/span>\u8003\u8651\u5230<\/span>\u773c<\/span>\u90e8\u7279<\/span>\u70b9<\/span>\uff0c\u5e94<\/span>\u5728<\/span>\u65b9<\/span>\u6848<\/span>\u4e2d<\/span>\u660e\u786e<\/span>\u7814<\/span>\u7a76<\/span>\u773c\u4e0e\u975e<\/span>\u7814<\/span>\u7a76\u773c<\/span>\u7684<\/span>\u786e<\/span>\u5b9a<\/span>\u6807\u51c6\u3002<\/span> <\/span><\/p>\n

 <\/span><\/p>\n

3.3  \u5bf9\u7167\u7684\u9009\u62e9<\/span><\/strong> <\/span><\/p>\n

\u5e94\u6839\u636e\u8bd5\u9a8c\u7684\u76ee\u7684\u548c\u603b\u4f53\u8bbe\u8ba1\u9009\u62e9\u5408\u9002\u7684\u5bf9\u7167\u7ec4\u3002\u5bf9\u7167\u53ef\u4ee5\u9009\u62e9\u73b0\u6709\u6807\u51c6\u6cbb\u7597\u3001\u5b89\u6170\u5242\u7b49\u3002\u5b89\u6170\u5242\u5bf9\u7167\u53ef\u4ee5\u91c7\u7528\u5047\u6ce8\u5c04\u7b49\u5f62\u5f0f\uff0c \u4ee5\u4fdd\u8bc1\u76f2\u6cd5\u7684\u5b9e\u65bd\u3002\u5bf9\u4e8e\u5df2\u6709\u540c\u7c7b\u4f5c\u7528\u673a\u5236\u836f\u7269\u4e0a\u5e02\u4f5c\u4e3a\u4e00\u7ebf\u6807\u51c6 \u6cbb\u7597\u7684\u60c5\u51b5\uff0c\u51fa\u4e8e\u4f26\u7406\u5b66\u8003\u8651\uff0c\u901a\u5e38\u5e94\u8fdb\u884c\u4ee5\u5df2\u4e0a\u5e02\u6807\u51c6\u4e00\u7ebf\u6cbb\u7597 \u836f\u7269\u4e3a\u9633\u6027\u5bf9\u7167\u7684\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/span><\/p>\n


<\/p>\n

3.4  \u518d\u6cbb\u7597\u6807\u51c6\u7684\u5236\u5b9a<\/span><\/strong><\/p>\n

\u5982\u679c\u62df\u8bc4\u4f30\u6309\u9700\u7ed9\u836f\uff08PRN\uff09\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\uff0c\u5e94\u5728\u8bd5\u9a8c\u8bbe\u8ba1 \u4e2d\u660e\u786e\u7ed9\u836f\u65b9\u6848\u4e0e\u518d\u6cbb\u7597\u6807\u51c6\uff0c\u5e76\u63d0\u4f9b\u79d1\u5b66\u6027\u4f9d\u636e\u3002\u5177\u4f53\u6807\u51c6\u5236\u5b9a \u65f6\uff0c\u5e94\u8003\u8651\u6d3b\u52a8\u6027\u75c5\u53d8\u7684\u6301\u7eed\u5b58\u5728\u3001\u6d3b\u52a8\u6027\u75c5\u53d8\u7684\u91cd\u65b0\u51fa\u73b0\uff0c\u6216\u65e0 \u5e94\u7b54\u72b6\u6001\u3002<\/span><\/p>\n

 <\/span><\/p>\n

3.5  \u7814\u7a76\u5468\u671f\u548c\u8bbf\u89c6\u9891\u7387<\/span><\/strong><\/p>\n

3.5.1\u7814\u7a76\u5468\u671f <\/span><\/strong><\/p>\n

\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\u4f5c\u4e3a\u4e00\u79cd\u957f\u671f\u7684\u9000\u884c\u6027\u75c5\u53d8\uff0c\u901a\u5e38\u60c5\u51b5\u4e0b<\/span>\u75be\u75c5\u8fdb<\/span>\u5c55<\/span>\u8f83\u4e3a<\/span>\u7f13<\/span>\u6162\uff0c<\/span>\u65b0<\/span>\u751f\u8840<\/span>\u7ba1<\/span>\u5b58\u5728<\/span>\u53cd\u590d<\/span>\u53d1\u4f5c\u7684<\/span>\u60c5<\/span>\u51b5\uff0c<\/span>\u56e0<\/span>\u6b64\u5728<\/span>\u5236<\/span>\u5b9a\u4e34 \u5e8a\u65b9\u6848<\/span>\u65f6<\/span>\u5e94\u7efc<\/span>\u5408<\/span>\u8bd5<\/span>\u9a8c<\/span>\u76ee<\/span>\u7684\u3001<\/span>\u4e3b<\/span>\u8981\u8bc4<\/span>\u4ef7\u6307<\/span>\u6807<\/span>\u3001<\/span>\u4ee5<\/span>\u53ca<\/span>\u4eba\u4f53<\/span>\u5bf9<\/span>\u836f\u7269<\/span>\u6cbb<\/span>\u7597\u7684 \u53cd\u5e94\u7b49<\/span>\u8bbe<\/span>\u8ba1<\/span>\u9002<\/span>\u5b9c<\/span>\u7684\u7814<\/span>\u7a76<\/span>\u5468\u671f<\/span>\u4ee5<\/span>\u8bc4\u4ef7<\/span>\u836f\u7269<\/span>\u6709\u6548\u6027<\/span>\u548c<\/span>\/<\/span>\u6216\u5b89<\/span>\u5168<\/span>\u6027\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u5bf9\u4e8e\u786e\u8bc1\u6027\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u9274\u4e8e\u65e9\u671f\u3001\u4e2d\u671fAMD\u53ca\u8fdb\u5c55\u671fGA\u7684\u75be\u75c5 \u8fdb\u7a0b\u7f13\u6162\uff0c\u7814\u7a76\u6301\u7eed\u65f6\u95f4\u5e94\u57281\u81f3\u6570\u5e74\uff1b\u6839\u636enAMD\u75c5\u53d8\u6301\u4e45\u6613\u590d\u53d1 \u7684\u7279\u70b9\uff0c\u7814\u7a76\u6301\u7eed\u65f6\u95f4\u5e94\u8db3\u4ee5\u89c2\u5bdf\u7597\u6548\u548c\u590d\u53d1\u60c5\u51b5\uff0c\u901a\u5e38\u5e94\u572812\u4e2a \u6708\u53ca\u4ee5\u4e0a\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u7814\u7a76\u5468\u671f\u7684\u4e0d\u540c\u53ef\u80fd\u4f1a\u4ea7\u751f\u4e0d\u540c\u7684\u7597\u6548\u7ed3\u8bba\uff0c\u5982\u77ed\u671f\u5185\u53ef\u663e\u8457 \u6539\u5584\u7ec8\u70b9\u6307\u6807\uff0c\u6216\u5177\u6709\u957f\u671f\u7597\u6548\u7b49\u3002\u4e3a\u5f97\u5230\u4e0d\u540c\u7684\u7ed3\u8bba\uff0c\u901a\u5e38\u9700\u8981 \u8fdb\u884c\u591a\u9879\u72ec\u7acb\u7684\u8bd5\u9a8c\u3002\u5982\u679c\u4e00\u9879\u8bd5\u9a8c\u662f\u4e3a\u4e86\u5f97\u51fa\u591a\u4e2a\u7ed3\u8bba\uff0c\u5219\u9700\u8981 \u9884\u5148\u505a\u8be6\u7ec6\u5408\u7406\u7684\u89c4\u5212\u3002<\/span><\/p>\n


<\/p>\n

3.5.2\u8bbf\u89c6\u9891\u7387<\/span><\/strong><\/p>\n

\u5e94\u6839\u636e\u4e0d\u540c\u7684\u76ee\u6807\u4eba\u7fa4\u3001\u4e0d\u540c\u836f\u7269\u7279\u70b9\u3001\u7ed9\u836f\u65b9\u6848\u3001\u6709\u6548\u6027\u8bc4\u4ef7\u6307\u6807\u548c\u5b89\u5168\u6027\u8bc4\u4ef7\u6307\u6807\u8bbe\u8ba1\u7b49\u7684\u9700\u8981\u7efc\u5408\u786e\u5b9a\u8bd5\u9a8c\u8bbf\u89c6\u9891\u7387\u3002<\/span><\/p>\n

3.6  \u7597\u6548\u8bc4\u4ef7<\/span><\/strong> <\/span><\/p>\n

\u6839\u636e\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\u7684\u75c5\u7406\u751f\u7406\u5b66\u3001\u4e34\u5e8a\u75c7\u72b6\u7b49\u7279\u70b9\uff0c\u8be5<\/span>\u75be\u75c5\u6cbb<\/span>\u7597<\/span>\u836f<\/span>\u7269<\/span>\u7684<\/span>\u7597\u6548<\/span>\u8bc4<\/span>\u4ef7\u6307<\/span>\u6807<\/span>\u901a<\/span>\u5e38<\/span>\u5e94<\/span>\u5305<\/span>\u62ec\u529f<\/span>\u80fd<\/span>\u5b66<\/span>\u6307<\/span>\u6807<\/span>\u3001<\/span>\u5f62\u6001<\/span>\u5b66<\/span>\u6307\u6807\u4ee5\u53ca\u89c6<\/span>\u529b<\/span>\u76f8\u5173<\/span>\u7684<\/span>\u751f\u6d3b<\/span>\u8d28<\/span>\u91cf\u7684<\/span>\u8bc4<\/span>\u4f30<\/span>\u3002<\/span>\u5176\u4e2d<\/span>\uff0c\u529f\u80fd<\/span>\u5b66<\/span>\u6307<\/span>\u6807<\/span>\u548c<\/span>\u5f62\u6001<\/span>\u5b66<\/span>\u6307\u6807 \u4e3a\u7814\u7a76<\/span>\u8005<\/span>\u8bc4\u4f30<\/span>\u7684<\/span>\u6307\u6807<\/span>\uff0c<\/span>\u89c6\u529b<\/span>\u76f8<\/span>\u5173<\/span>\u7684<\/span>\u751f\u6d3b<\/span>\u8d28\u91cf\u7684<\/span>\u8bc4<\/span>\u4f30\u4e3a<\/span>\u60a3<\/span>\u8005\u8bc4<\/span>\u4f30<\/span>\u7684<\/span>\u6307 \u6807\u3002\u901a<\/span>\u8fc7<\/span>\u7814\u7a76<\/span>\u8005<\/span>\u548c\u60a3<\/span>\u8005<\/span>\u4e24\u65b9<\/span>\u9762<\/span>\u7684\u8bc4<\/span>\u4f30<\/span>\u6709<\/span>\u52a9<\/span>\u4e8e<\/span>\u66f4<\/span>\u4e3a<\/span>\u51c6\u786e<\/span>\u5730<\/span>\u53cd\u6620<\/span>\u7597<\/span>\u6548\u7ed3 \u679c\u3002<\/span><\/p>\n


<\/p>\n

\u529f\u80fd\u5b66\u6307\u6807\u5305\u62ec\uff0c\u91c7\u7528\u65e9\u671f\u6cbb\u7597\u7cd6\u5c3f\u75c5\u89c6\u7f51\u819c\u75c5\u53d8\u7814\u7a76<\/span>\uff08<\/span>ET<\/span>D<\/span>R<\/span>S<\/span>\uff09<\/span>\u89c6\u529b<\/span>\u8868<\/span>\u8bc4\u4f30<\/span>\u7814<\/span>\u7a76<\/span>\u773c<\/span>\u7684<\/span>\u6700\u4f73<\/span>\u77eb<\/span>\u6b63\u89c6\u529b<\/span>\uff08<\/span>BCVA<\/span>\uff09\u8f83<\/span>\u57fa<\/span>\u7ebf<\/span>\u53d8 \u5316\u7684\u60c5<\/span>\u51b5<\/span>\uff08\u5305<\/span>\u62ec<\/span>\u89c6<\/span>\u529b<\/span>\u7a33<\/span>\u5b9a\u3001<\/span>\u63d0<\/span>\u9ad8\u6216<\/span>\u5728\u4e00<\/span>\u5b9a\u8303\u56f4<\/span>\u5185<\/span>\u4e0b\u964d<\/span>\uff08<\/span>\u5982\u4e0b<\/span>\u964d<\/span>\u5c0f\u4e8e<\/span>15\u4e2a\u5b57<\/span>\u6bcd<\/span>\uff09\u7b49<\/span>\uff09<\/span>\uff0c<\/span>\u4ee5<\/span>\u53ca<\/span>\u89c6\u91ce<\/span>\u9608<\/span>\u503c\u3001<\/span>\u8272\u89c9<\/span>\u654f\u611f\u5ea6<\/span>\u3001<\/span>\u89c6\u89c9<\/span>\u7535<\/span>\u751f\u7406<\/span>\u68c0<\/span>\u67e5\u632f\u5e45\u548c\u6f5c<\/span>\u4f0f<\/span>\u671f\u7b49<\/span>\u529f<\/span>\u80fd\u5b66<\/span>\u6307<\/span>\u6807\u53d8<\/span>\u5316<\/span>\u3002<\/span><\/p>\n

 <\/span> <\/span><\/p>\n

\u5f62\u6001\u5b66\u6307\u6807\u5305\u62ec\uff0c\u91c7\u7528\u5149\u5b66\u76f8\u5e72\u65ad\u5c42\u626b\u63cf\uff08OCT\uff09\u6d4b\u5b9a\u7684\u4e2d\u5fc3 \u89c6\u7f51\u819c\u539a\u5ea6\uff1b\u91c7\u7528\u773c\u5e95\u955c\u68c0\u67e5\u3001\u773c\u5e95\u7167\u76f8\u672f\u3001\u773c\u5e95\u8367\u5149\u7d20\u8840\u7ba1\u9020\u5f71\u3001\u773c\u5e95\u81ea\u53d1\u8367\u5149\u7b49\u68c0\u67e5\u65b9\u6cd5\u5bf9\u7814\u7a76\u773c\u89c6\u7f51\u819c\u8840\u7ba1\u7684\u89e3\u5256\u72b6\u6001\u8fdb\u884c \u8bc4\u4f30\uff0c\u5305\u62ec\u603b\u75c5\u53d8\u9762\u79ef\u3001\u8109\u7edc\u819c\u65b0\u751f\u8840\u7ba1\uff08CNV\uff09\u9762\u79ef\u3001\u8367\u5149\u7d20\u6e17\u6f0f\u7b49\u8bc4\u4f30\u75c5\u7076\u5927\u5c0f\u76f8\u5bf9\u57fa\u7ebf\u7684\u53d8\u5316\u60c5\u51b5\u3002<\/span><\/p>\n


<\/p>\n

\u89c6\u529b\u76f8\u5173\u751f\u6d3b\u8d28\u91cf\u7684\u8bc4\u4f30\uff0c\u91c7\u7528\u7f8e\u56fd\u56fd\u5bb6\u773c\u79d1\u7814\u7a76\u624025\u9879\u89c6\u89c9<\/span>\u529f\u80fd\u95ee<\/span>\u5377<\/span>\uff08<\/span>N<\/span>E<\/span>I<\/span>V<\/span>F<\/span>Q<\/span>–<\/span>25\uff09<\/span>\u6765<\/span>\u8bc4<\/span>\u4f30<\/span>\u60a3<\/span>\u8005<\/span>\u5bf9<\/span>\u89c6\u89c9\u76f8<\/span>\u5173<\/span>\u673a\u80fd<\/span>\u548c<\/span>\u89c6\u89c9<\/span>\u76f8<\/span>\u5173\u751f \u6d3b\u8d28\u91cf<\/span>\u7684<\/span>\u611f\u77e5<\/span>\u3002<\/span>\u6838\u5fc3<\/span>\u6d4b<\/span>\u5b9a\u6307<\/span>\u6807<\/span>\u5305<\/span>\u62ec<\/span>2<\/span>5<\/span>\u4e2a<\/span>\u9879\u76ee\uff0c<\/span>\u542b<\/span>1<\/span>1<\/span>\u4e2a\u89c6<\/span>\u89c9<\/span>\u76f8\u5173<\/span>\u5b50<\/span>\u91cf \u8868\u548c1\u4e2a<\/span>\u5065<\/span>\u5eb7\u603b<\/span>\u4f53<\/span>\u72b6\u51b5<\/span>\u9879<\/span>\u76ee\u3002<\/span>\u5b50<\/span>\u91cf\u8868<\/span>\u8bc4\u5206<\/span>\u5305\u62ec\u4e00<\/span>\u822c<\/span>\u89c6\u89c9<\/span>\u3001<\/span>\u773c\u90e8<\/span>\u75bc<\/span>\u75db\u3001 \u8fd1\u8ddd\u79bb<\/span>\u6d3b<\/span>\u52a8<\/span>\u3001<\/span>\u8fdc<\/span>\u8ddd\u79bb<\/span>\u6d3b<\/span>\u52a8\u3001<\/span>\u793e<\/span>\u4f1a\u529f<\/span>\u80fd\u3001<\/span>\u7cbe\u795e\u5065<\/span>\u5eb7<\/span>\u3001\u89d2<\/span>\u8272<\/span>\u56f0\u96be<\/span>\u3001<\/span>\u4f9d\u8d56\u3001\u9a7e<\/span>\u9a76<\/span>\u3001\u8272<\/span>\u89c6<\/span>\u89c9\u548c<\/span>\u5916<\/span>\u5468\u89c6<\/span>\u89c9<\/span>\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u5e94\u6ce8\u610f\uff0c\u4e3b\u8981\u548c\u5173\u952e\u6b21\u8981\u6709\u6548\u6027\u6307\u6807\u7684\u9009\u62e9\u5fc5\u987b\u662f\u7ecf\u8fc7\u4e34\u5e8a\u8bd5 \u9a8c\u9a8c\u8bc1\u7684\u3001\u5b66\u672f\u754c\u516c\u8ba4\u7684\u7ec8\u70b9\u6307\u6807\uff08\u5982\u91c7\u7528ETDRS\u89c6\u529b\u8868\uff0cVFQ-25 \u89c6\u529f\u80fd\u91cf\u8868\u7b49\u8bc4\u4f30\u7684\u7ec8\u70b9\uff09\u3002\u5173\u952e\u6027\u7684\u8bd5\u9a8c\u65b9\u6848\u8bbe\u8ba1\u4e2d\u9009\u62e9\u7684\u4e3b\u8981\u773c\u5e95\u5f71\u50cf\u5b66\u68c0\u67e5\u8bc4\u4f30\u7684\u5f62\u6001\u5b66\u7597\u6548\u6307\u6807\uff08\u5982\u773c\u5e95\u5f69\u7167\u3001\u8367\u5149\u7d20\u8840\u7ba1 \u9020\u5f71\u3001\u8109\u7edc\u819c\u8840\u7ba1\u9020\u5f71\u3001\u5149\u5b66\u76f8\u5e72\u65ad\u5c42\u626b\u63cf\u3001\u81ea\u53d1\u8367\u5149\u7b49\uff09\u5e94\u7531\u8bfb \u7247\u4e2d\u5fc3\u7edf\u4e00\u8bc4\u4f30\u4ee5\u4fdd\u8bc1\u6570\u636e\u7684\u4e00\u81f4\u6027\u4e0e\u6807\u51c6\u89e3\u8bfb\u3002\u5e76\u4e14\uff0c\u5728\u8bd5\u9a8c\u5f00 \u59cb\u4e4b\u524d\uff0c\u6240\u6709\u7814\u7a76\u4eba\u5458\u3001\u64cd\u4f5c\u4eba\u5458\u3001\u8bc4\u4f30\u4eba\u5458\u5747\u5e94\u7ecf\u8fc7\u7cfb\u7edf\u4e13\u4e1a\u57f9\u8bad\u548c\u8d44\u683c\u8ba4\u8bc1\uff08\u5982\u89c6\u529b\u8bc4\u4f30\u8ba4\u8bc1\u3001\u773c\u5e95\u5f71\u50cf\u5b66\u68c0\u67e5\u8ba4\u8bc1\u7b49\uff09\uff0c\u5e76\u5e94 \u5bf9\u89c6\u529b\u68c0\u67e5\u5ba4\u3001\u4eea\u5668\u8bbe\u5907\u3001\u7cfb\u7edf\u3001\u8f6f\u4ef6\u7b49\u8bc4\u4f30\u65b9\u6cd5\u548c\u5de5\u5177\u8fdb\u884c\u9a8c \u8bc1\u3002<\/span><\/p>\n

 <\/span> <\/span><\/p>\n

\u968f\u7740\u79d1\u5b66\u6280\u672f\u7684\u4e0d\u65ad\u8fdb\u6b65\uff0c\u7533\u529e\u8005\u5e94\u5c3d\u53ef\u80fd\u91c7\u7528\u66f4\u4e3a\u5148\u8fdb\u3001\u53ef \u9760\u7684\u68c0\u67e5\u8bbe\u5907\u3001\u5de5\u5177\u548c\u65b9\u6cd5\uff0c\u5bf9\u65b0\u836f\u7597\u6548\u8fdb\u884c\u8bc4\u4ef7\u3002\u5f53\u91c7\u7528\u65b0\u65b9\u6cd5\u8fdb\u884c\u8bc4\u4ef7\u65f6\uff0c\u9700\u8fdb\u884c\u8bc4\u4f30\u548c\u9a8c\u8bc1\uff0c\u5e76\u63d0\u4f9b\u652f\u6301\u6027\u8bc1\u636e\u3002<\/span><\/p>\n

 <\/span><\/strong><\/p>\n

3.6.1\u63a2\u7d22\u6027\u4e34\u5e8a\u8bd5\u9a8c\u7597\u6548\u6307\u6807<\/span><\/strong><\/p>\n

\u63a2\u7d22\u6027\u8bd5\u9a8c\u9636\u6bb5\u53ef\u4ee5\u5bf9\u591a\u79cd\u7597\u6548\u6307\u6807\u8fdb\u884c\u7814\u7a76\uff0c\u5982BCVA\u8f83\u57fa\u7ebf<\/span>\u6539\u5584\u7684<\/span>\u5b57<\/span>\u6bcd\u6570<\/span>\uff0c<\/span>\u6216\u5e73<\/span>\u5747<\/span>\u4e2d\u5fc3<\/span>\u89c6<\/span>\u7f51\u819c<\/span>\u539a<\/span>\u5ea6<\/span>\u3001<\/span>\u6e17\u6f0f\u9762<\/span>\u79ef\u7b49<\/span>O<\/span>C<\/span>T<\/span>\u6216FA\u5f71<\/span>\u50cf\u5b66 \u6307\u6807<\/span>\uff0c<\/span>\u6216<\/span>NE<\/span>I<\/span>VFQ-25<\/span>\u89c6<\/span>\u529f<\/span>\u80fd\u91cf<\/span>\u8868<\/span>\u7b49<\/span>\uff0c<\/span>\u53ef<\/span>\u6839\u636e\u836f<\/span>\u7269<\/span>\u7684\u7279<\/span>\u70b9<\/span>\u9009\u62e9<\/span>\u76f8<\/span>\u5e94\u7684\u7597 \u6548<\/span>\u6307\u6807<\/span>\u8fdb<\/span>\u884c\u5145<\/span>\u5206<\/span>\u7684\u63a2<\/span>\u7d22<\/span>\uff0c\u4e3a<\/span>\u540e<\/span>\u671f<\/span>\u786e<\/span>\u8bc1\u6027<\/span>\u8bd5<\/span>\u9a8c\u63d0<\/span>\u4f9b<\/span>\u5145\u5206<\/span>\u7684<\/span>\u4fe1\u606f<\/span>\u548c<\/span>\u4f9d<\/span>\u636e\u3002<\/span><\/p>\n

 <\/span><\/p>\n

3.6.2\u786e\u8bc1\u6027\u4e34\u5e8a\u8bd5\u9a8c\u7597\u6548\u6307\u6807<\/span><\/strong><\/p>\n

\u5728\u786e\u8bc1\u6027\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u4e3b\u8981\u7597\u6548\u6307\u6807\u5e94\u9009\u62e9\u5df2\u6709\u7684\u3001\u516c\u8ba4\u7684\u51c6\u5219\u548c\u6807\u51c6,\u80fd\u9ad8\u6548\u4e14\u53ef\u4fe1\u5730\u53cd\u6620\u60a3\u8005\u771f\u6b63\u83b7\u76ca\uff0c\u5c3d\u91cf\u5ba2\u89c2\u4e14\u53ef\u91cf\u5316\u3002\u786e\u8bc1\u6027\u8bd5\u9a8c\u662f\u6839\u636e\u8bd5\u9a8c\u7684\u4e3b\u8981\u76ee\u7684\u76f4\u63a5\u63d0\u51fa\u5e76\u4e8b\u5148\u5b9a\u4e49\u5047\u8bbe\uff0c\u5728\u8bd5\u9a8c\u5b8c\u6210\u540e \u8fdb\u884c\u68c0\u9a8c\u7684\u5bf9\u7167\u8bd5\u9a8c\u3002\u901a\u5e38\uff0c\u901a\u8fc7\u786e\u8bc1\u6027\u8bd5\u9a8c\u63d0\u4f9b\u652f\u6301\u65b0\u836f\u4e0a\u5e02\u7684\u6709 \u6548\u6027\u548c\u5b89\u5168\u6027\u7684\u6709\u529b\u8bc1\u636e\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u76ee\u524d\uff0c\u76f8\u5bf9\u4e8e\u65e9\u671f\u548c\u4e2d\u671fAMD\uff0c\u5bf9AMD\u7684\u836f\u7269\u7814\u53d1\u4e3b\u8981\u96c6\u4e2d\u4e8e\u8fdb \u5c55\u671fAMD\uff0c\u6240\u4ee5\u4ee5\u4e0b\u8ba8\u8bba\u4e3b\u8981\u9488\u5bf9\u8fdb\u5c55\u671fAMD\u3002\u4f46\u968f\u7740\u533b\u5b66\u79d1\u6280\u7684 \u8fdb\u5c55\uff0c\u5c06\u6765\u5982\u6709\u9488\u5bf9\u65e9\u671f\u548c\u4e2d\u671fAMD\u6cbb\u7597\u7684\u7814\u7a76\u836f\u7269\uff0c\u5219\u5176\u7597\u6548\u8bc4\u4ef7 \u7684\u91cd\u70b9\u5e94\u5173\u6ce8\u5982\u4f55\u964d\u4f4e\u8fdb\u5c55\u671f\u75be\u75c5\u7684\u53d1\u751f\u7387\u4ee5\u53ca\u5ef6\u7f13\u75be\u75c5\u7684\u8fdb\u5c55\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u4e3b\u8981\u7597\u6548\u7ec8\u70b9\uff1a<\/span><\/p>\n

\u5bf9\u4e8e\u65b0\u751f\u8840\u7ba1\u6027AMD\uff0c\u5efa\u8bae\u91c7\u7528\u201c\u6cbb\u759712\u4e2a\u6708\u65f6BCVA\u8f83\u57fa\u7ebf \u6539\u5584\u7684\u5b57\u6bcd\u6570\u201d\u548c\u201cBCVA\u8f83\u57fa\u7ebf\u6539\u558415\u4e2a\u5b57\u6bcd\u7684\u53d7\u8bd5\u8005\u7684\u6bd4 \u4f8b\u201d\u3002\u5bf9\u4e8e\u5730\u56fe\u6837\u840e\u7f29\uff0c\u53ef\u6839\u636e\u7814\u7a76\u8fdb\u5c55\u8003\u8651\u9009\u62e9\u529f\u80fd\u6027\u548c\/\u6216\u5f62\u6001 \u5b66\u6307\u6807\u4f5c\u4e3a\u4e3b\u8981\u7597\u6548\u6307\u6807\uff0c\u53ef\u91c7\u7528\u4e0e\u57fa\u7ebf\u76f8\u6bd4\uff0c\u9ec4\u6591\u533a\u5730\u56fe\u6837\u840e\u7f29\u9762\u79ef\u7684\u6539\u53d8\u6216CNV\u7684\u53d1\u751f\u201d\u7b49\u5f62\u6001\u5b66\u6307\u6807\u4f5c\u4e3a\u4e3b\u8981\u7597\u6548\u6307\u6807\u3002\u4e34\u5e8a<\/span>\u7597\u6548\u89c6<\/span>\u529f<\/span>\u80fd\u7684<\/span>\u6539<\/span>\u5584\u4f5c<\/span>\u4e3a<\/span>\u5173\u952e<\/span>\u7684<\/span>\u6b21\u8981<\/span>\u7597\u6548<\/span>\u6307\u6807<\/span>\u3002\u8bc4<\/span>\u4ef7<\/span>\u548c<\/span>\u968f<\/span>\u8bbf\u7684<\/span>\u65f6<\/span>\u95f4\u70b9<\/span>\u7684\u9009\u62e9<\/span>\u5e94<\/span>\u6839\u636e<\/span>\u75be<\/span>\u75c5\u75c5<\/span>\u7a0b<\/span>\u3001\u836f<\/span>\u7269<\/span>\u4f5c\u7528<\/span>\u81f3\u89c2<\/span>\u5bdf\u5230\u660e<\/span>\u786e<\/span>\u6307\u6807<\/span>\u9700<\/span>\u8981\u7684<\/span>\u65f6<\/span>\u95f4\u3001\u5bf9\u7167\u836f<\/span>\u7269<\/span>\u7684\u4f5c<\/span>\u7528<\/span>\u65f6\u95f4<\/span>\u53ca<\/span>\u6548\u679c<\/span>\u7b49<\/span>\u8fdb\u884c<\/span>\u7efc\u5408<\/span>\u8003\u8651\u3002<\/span><\/p>\n


<\/p>\n

\u6b21\u8981\u7597\u6548\u7ec8\u70b9\uff1a<\/span><\/p>\n

\u6b21\u8981\u7ec8<\/span>\u70b9<\/span>\u8bc4\u4f30<\/span>\u5176<\/span>\u4ed6\u53ef<\/span>\u80fd<\/span>\u4e0e\u4e3b<\/span>\u8981<\/span>\u76ee\u7684<\/span>\u6709\u5173<\/span>\u7684\u652f\u6301<\/span>\u6027<\/span>\u6307\u6807<\/span>\u6216<\/span>\u8005\u662f\u4e0e\u6b21\u8981\u76ee<\/span>\u7684<\/span>\u6709\u5173<\/span>\u7684<\/span>\u7597<\/span>\u6548<\/span>\u6307<\/span>\u6807\uff0c<\/span>\u901a<\/span>\u5e38<\/span>\u5e94<\/span>\u9009\u62e9<\/span>\u4e0e<\/span>AMD<\/span>\u75be\u75c5<\/span>\u76f4<\/span>\u63a5\u76f8<\/span>\u5173<\/span>\uff0c\u5177\u6709 \u4e34\u5e8a\u610f<\/span>\u4e49<\/span>\u7684\u7597<\/span>\u6548<\/span>\u6307<\/span>\u6807<\/span>\u3002<\/span>
<\/p>\n

 <\/span><\/p>\n

\u5bf9\u4e8e\u65b0\u751f\u8840\u7ba1\u6027AMD\uff0c\u53ef\u8003\u8651\u7684\u6b21\u8981\u6709\u6548\u6027\u6307\u6807\u5305\u62ec\u4f46\u4e0d\u9650\u4e8e\uff1a<\/span><\/p>\n

 <\/span><\/p>\n

\u89c6\u529f\u80fd\u6307\u6807\uff0c\u6839\u636eETDRS\u89c6\u529b\u8868\u8bc4\u4f30\uff0c\u6700\u4f73\u77eb\u6b63\u89c6\u529b\u8f83\u57fa\u7ebf\u6539 \u5584\u5927\u4e8e5\u300110\u300115\u4e2a\u5b57\u6bcd\uff0c\u6700\u4f73\u77eb\u6b63\u89c6\u529b\u8f83\u57fa\u7ebf\u4e27\u5931\u5c0f\u4e8e5\u300110\u300115 \u4e2a\u5b57\u6bcd\u7684\u60a3\u8005\u767e\u5206\u6bd4\uff1b\u6700\u4f73\u77eb\u6b63\u89c6\u529b\u6539\u5584\u5927\u4e8e\u7b49\u4e8e30\u4e2a\u5b57\u6bcd\u7684\u767e\u5206 \u6bd4\uff08\u5fc5\u8981\u65f6\uff09\uff1b\u89c6\u529b\u8fbe\u523020\/40\u6216\u66f4\u4f73\u7684\u53d7\u8bd5\u8005\u6bd4\u4f8b\uff1b\u89c6\u529b\u8fbe\u5230<\/span>20\/20<\/span>0<\/span>\u6216<\/span>\u66f4<\/span>\u4f73<\/span>\u7684<\/span>\u6bd4<\/span>\u4f8b<\/span>\uff1b<\/span>\u7b49\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u89c6\u7f51\u819c\u5f62\u6001\u5b66\u6307\u6807\uff0c\u6839\u636eOCT\u8bc4\u4f30\uff0cCRT\u76f8\u5bf9\u4e8e\u57fa\u7ebf\u7684\u53d8\u5316\uff1b \u8109\u7edc\u819c\u65b0\u751f\u8840\u7ba1\uff08CNV\uff09\u9762\u79ef\u76f8\u5bf9\u4e8e\u57fa\u7ebf\u7684\u53d8\u5316\uff1b\u6839\u636eFA\u8bc4\u4f30\uff0c\u8367 \u5149\u7d20\u6e17\u6f0f\u5b8c\u5168\u6d88\u9000\u7684\u6bd4\u4f8b\u3001\u8367\u5149\u7d20\u6e17\u6f0f\u9762\u79ef\u76f8\u5bf9\u4e8e\u57fa\u7ebf\u7684\u53d8\u5316\u3001\u603b\u635f\u4f24\u9762\u79ef\u76f8\u5bf9\u4e8e\u57fa\u7ebf\u7684\u53d8\u5316\u3001\u89c6\u7f51\u819c\u5185\u65e0\u79ef\u6db2\u7684\u60a3\u8005\u6bd4\u4f8b\u3001\u89c6\u7f51\u819c\u4e0b\u65e0\u79ef\u6db2\u7684\u60a3\u8005\u6bd4\u4f8b\u3001\u89c6\u7f51\u819c\u4e0b\u548c\u89c6\u7f51\u819c\u5185\u65e0\u79ef\u6db2\u7684\u6bd4\u4f8b\uff1b\u7b49\u3002<\/span><\/p>\n


<\/p>\n

\u89c6\u529b\u76f8\u5173\u751f\u6d3b\u8d28\u91cf\u8bc4\u4f30\uff0cNEIVFQ-25\u91cf\u8868\u603b\u8bc4\u5206\u76f8\u5bf9\u4e8e\u57fa\u7ebf\u7684<\/span>\u53d8\u5316\uff1b<\/span>NE<\/span>I<\/span>V<\/span>F<\/span>Q<\/span>–<\/span>2<\/span>5<\/span>\u5b50<\/span>\u91cf\u8868<\/span>\uff08<\/span>\u8fd1\u8ddd<\/span>\u79bb<\/span>\u8fd0<\/span>\u52a8<\/span>\u3001<\/span>\u8fdc\u8ddd<\/span>\u79bb<\/span>\u6d3b\u52a8<\/span>\u3001<\/span>\u89c6\u529b<\/span>\u4f9d<\/span>\u8d56\u6027 \u7b49\uff09\u8bc4<\/span>\u5206<\/span>\u76f8\u5bf9<\/span>\u4e8e<\/span>\u57fa\u7ebf<\/span>\u7684<\/span>\u53d8\u5316\uff1b\u7b49\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u6309\u9700\u7ed9\u836f\uff08prn\u6cbb\u7597\uff09\u6709\u6548\u6027\u8bc4\u4f30\uff08\u5982\u6709\uff09\uff1a\u6ce8\u5c04\u6b21\u6570\u7b49\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u4e0a\u8ff0\u7597\u6548\u7ec8\u70b9\u548c\u76f8\u5e94\u7684\u5206\u6790\u8ba1\u5212\u5e94\u5728\u8bd5\u9a8c\u65b9\u6848\u4e2d\u9884\u5148\u8bf4\u660e\uff08\u81f3 \u5c11\u5728\u6570\u636e\u5e93\u9501\u5b9a\u4e4b\u524d\uff09\u3002<\/span><\/p>\n

 <\/span><\/p>\n

3.7\u5b89\u5168\u6027\u8bc4\u4ef7<\/span><\/strong><\/p>\n

\u5bf9\u4e8e\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\u6cbb\u7597\u836f\u7269\u7684\u5b89\u5168\u6027\u8bc4\u4ef7\uff0c\u7814\u7a76\u60a3\u8005\u4eba \u7fa4\u7684\u66b4\u9732\u7a0b\u5ea6\u5e94\u9075\u5faaICHE1A\u7684\u5efa\u8bae\u3002\u9700\u8981\u83b7\u5f97\u77ed\u671f\u5bf9\u7167\u7814\u7a76\u4ee5\u53ca\u957f\u671f\u5bf9\u7167\u548c\/\u6216\u5f00\u653e\u7814\u7a76\u7684\u6570\u636e\u3002<\/span><\/p>\n


<\/span><\/p>\n

\u5b89\u5168\u6027\u6307\u6807\u7684\u8bbe\u8ba1\u5e94\u57fa\u4e8e\u5bf9\u7814\u7a76\u836f\u7269\u4f5c\u7528\u673a\u5236\u7279\u70b9\u3001\u7ed9\u836f\u9014\u5f84<\/span>\uff08\u5982\u73bb<\/span>\u7483<\/span>\u4f53\u5185<\/span>\u6ce8<\/span>\u5c04\u3001<\/span>\u7f13<\/span>\u91ca\u5236<\/span>\u5242<\/span>\u690d\u5165<\/span>\u7269\u7b49<\/span>\uff09\u7279\u70b9<\/span>\u3001<\/span>\u975e\u4e34<\/span>\u5e8a<\/span>\u5b89\u5168<\/span>\u6027<\/span>\u4fe1\u606f\u3001\u540c<\/span>\u7c7b<\/span>\u836f\u7269<\/span>\u5df2<\/span>\u77e5\u5b89<\/span>\u5168<\/span>\u6027\u4fe1<\/span>\u606f<\/span>\u548c<\/span>\u6f5c<\/span>\u5728\u98ce<\/span>\u9669<\/span>\u7b49\u7efc<\/span>\u5408<\/span>\u8bc4\u4f30<\/span>\u540e<\/span>\u786e\u5b9a\u3002<\/span><\/p>\n

 <\/span><\/p>\n

 <\/span>\u5b89\u5168\u6027<\/span>\u8bc4<\/span>\u4ef7\u9700<\/span>\u540c<\/span>\u65f6\u8bc4<\/span>\u4f30<\/span>\u773c\u5c40<\/span>\u90e8<\/span>\u5b89\u5168<\/span>\u6027\u548c<\/span>\u5168\u8eab\u5b89<\/span>\u5168<\/span>\u6027<\/span>\u3002<\/span>\u5b89\u5168<\/span>\u6027<\/span>\u6307\u6807\u5305<\/span>\u62ec\uff1a<\/span>\u6b7b<\/span>\u4ea1<\/span>\u3001<\/span>\u4e25<\/span>\u91cd\u4e0d<\/span>\u826f<\/span>\u4e8b<\/span>\u4ef6<\/span>\u548c<\/span>\u4e0d<\/span>\u826f<\/span>\u4e8b\u4ef6<\/span>\u3001<\/span>\u4e34\u5e8a<\/span>\u5b9e<\/span>\u9a8c\u5ba4<\/span>\u68c0<\/span>\u67e5\uff08<\/span>\u8840<\/span>\u6db2<\/span>\u5b66<\/span>\u3001 \u8840\u751f\u5316<\/span>\u3001<\/span>\u5c3f<\/span>\u6db2<\/span>\uff09<\/span>\u3001<\/span>\u773c<\/span>\u5185<\/span>\u538b<\/span>\uff08<\/span>IOP<\/span>\uff09<\/span>\u76d1\u6d4b<\/span>\u3001<\/span>\u51dd\u8840\u9176<\/span>\u539f<\/span>\u65f6\u95f4<\/span>\u3001<\/span>\u90e8<\/span>\u5206\u51dd<\/span>\u8840<\/span>\u6d3b\u9176 \u65f6\u95f4<\/span>\u3001<\/span>\u56fd<\/span>\u9645<\/span>\u6807\u51c6<\/span>\u5316<\/span>\u6bd4<\/span>\u503c<\/span>\u3001<\/span>\u5fc3\u7535<\/span>\u56fe<\/span>\uff08<\/span>ECG<\/span>\uff09<\/span>\u3001<\/span>\u751f\u547d\u4f53<\/span>\u5f81<\/span>\u3001<\/span>\u773c<\/span>\u79d1<\/span>\u68c0<\/span>\u67e5<\/span>\uff08<\/span>\u773c\u5185 \u538b\u6d4b\u5b9a<\/span>\u3001<\/span>\u95f4\u63a5<\/span>\u68c0<\/span>\u773c\u955c<\/span>\u3001<\/span>\u88c2\u9699<\/span>\u706f<\/span>\u6d3b\u7ec4<\/span>\u7ec7\u663e<\/span>\u5fae<\/span>\u955c<\/span>\u68c0<\/span>\u67e5<\/span>\u7b49<\/span>\uff09<\/span>\u7b49<\/span>\u3002<\/span><\/p>\n


<\/p>\n

\u5b89\u5168\u6027\u8bc4\u4ef7\u5e94\u5173\u6ce8\u4ee5\u4e0b\u65b9\u9762\uff1a\uff081\uff09\u4e25\u91cd\u7684\uff08\u5371\u53ca\u89c6\u529b\u7684\uff09\u773c\u90e8<\/span>\u4e0d\u826f\u4e8b<\/span>\u4ef6<\/span>\uff1a\u89c6<\/span>\u529b<\/span>\u4e0b<\/span>\u964d<\/span>><\/span>30<\/span>\u4e2a<\/span>\u5b57<\/span>\u6bcd<\/span>\u4e14<\/span>\u6301\u7eed<\/span>1<\/span>\u5c0f\u65f6\u4ee5<\/span>\u4e0a<\/span>\uff1b\u89c6<\/span>\u529b<\/span>\u4e0b\u964d<\/span>\u5230<\/span>\u5149\u611f \u6216\u4ee5\u4e0b<\/span>\u6c34<\/span>\u5e73<\/span>\u4e14<\/span>\u6ce8<\/span>\u5c04\u540e<\/span>\u6301<\/span>\u7eed<\/span>1\u5c0f<\/span>\u65f6<\/span>\u4ee5\u4e0a<\/span>\uff1b<\/span>\u9700<\/span>\u8981\u533b<\/span>\u5b66<\/span>\u5e72<\/span>\u9884\u6216<\/span>\u624b<\/span>\u672f\u5e72<\/span>\u9884<\/span>\u6765\u9884\u9632\u6c38\u4e45<\/span>\u6027<\/span>\u5931\u660e<\/span>\u7684<\/span>\u4e0d\u826f<\/span>\u4e8b<\/span>\u4ef6<\/span>\uff1b<\/span>\u91cd<\/span>\u5ea6\u773c<\/span>\u5185\u708e<\/span>\u75c7<\/span>\u7b49\uff1b<\/span>\uff08<\/span>2<\/span>\uff09\u9700<\/span>\u5173<\/span>\u6ce8<\/span>\u7684<\/span>\u5176<\/span>\u5b83\u773c \u90e8\u4e0d\u826f<\/span>\u4e8b<\/span>\u4ef6<\/span>\uff1a<\/span>\u5305<\/span>\u62ec\u4efb<\/span>\u4f55<\/span>\u773c\u5185<\/span>\u708e<\/span>\u75c7<\/span>\uff1b<\/span>\u6cbb\u7597<\/span>\u65e0<\/span>\u6548<\/span>\u7684<\/span>\u65b0<\/span>\u53d1<\/span>IOP<\/span>\u53ca<\/span>\u9700<\/span>\u8981\u6cbb<\/span>\u7597<\/span>\u7684 <\/span>I<\/span>O<\/span>P<\/span>\uff0c<\/span>\u89d2\u819c<\/span>\u6c34<\/span>\u80bf<\/span>\uff0c<\/span>\u5de9<\/span>\u819c<\/span>\u75c5<\/span>\u53d8<\/span>\u3001\u7814<\/span>\u7a76<\/span>\u773c<\/span>\u7684<\/span>BC<\/span>V<\/span>A<\/span>\u51fa<\/span>\u73b0\u4efb<\/span>\u4f55<\/span>\u7a81\u7136<\/span>\u7684<\/span>\u3001\u4e34\u5e8a \u4e0a\u663e\u8457<\/span>\u7684<\/span>\u964d<\/span>\u4f4e<\/span>\u7b49<\/span>\uff09\uff1b<\/span>\uff08<\/span>3<\/span>\uff09\u9700<\/span>\u5173<\/span>\u6ce8<\/span>\u7684<\/span>\u5176\u5b83<\/span>\u4e0d\u826f\u4e8b<\/span>\u4ef6<\/span>\uff1a\u5305<\/span>\u62ec<\/span>\u514d\u75ab<\/span>\u539f<\/span>\u6027\u5bfc\u81f4\u7684\u975e<\/span>\u611f<\/span>\u67d3<\/span>\u6027<\/span>\u773c<\/span>\u90e8\u708e<\/span>\u75c7<\/span>\u3001\u52a8<\/span>\u8109<\/span>\u8840\u6813<\/span>\u6813\u585e<\/span>\u4e8b\u4ef6<\/span>\uff08<\/span>A<\/span>T<\/span>E<\/span>\uff09\u3001<\/span>\u514d<\/span>\u75ab\u539f<\/span>\u6027<\/span>\u76f8 \u5173\u7684\u5168<\/span>\u8eab<\/span>\u6027\u53cd<\/span>\u5e94<\/span>\u3001\u9ad8<\/span>\u8840<\/span>\u538b\u3001<\/span>\u9f3b<\/span>\u7c98\u819c<\/span>\u7684\u7cdc<\/span>\u70c2\u548c\u6e83<\/span>\u75a1<\/span>\u3001\u89c6<\/span>\u7f51<\/span>\u819c\u8272<\/span>\u7d20<\/span>\u4e0a\u76ae<\/span>\uff08<\/span>RPE<\/span>\uff09\u6495<\/span>\u88c2<\/span>\u3001\u80da<\/span>\u80ce<\/span>–<\/span>\u80ce<\/span>\u513f<\/span>\u6bd2\u6027<\/span>\u7b49<\/span>\u3002<\/span>\uff084<\/span>\uff09\u73bb\u7483<\/span>\u4f53<\/span>\u5185\u6ce8<\/span>\u5c04<\/span>\u7b49<\/span>\u64cd<\/span>\u4f5c<\/span>\u76f8\u5173\u7684\u4e0d\u826f<\/span>\u4e8b<\/span>\u4ef6<\/span>\uff0c<\/span>\u5305<\/span>\u62ec\u611f<\/span>\u67d3<\/span>\u6027\u773c<\/span>\u5185<\/span>\u708e\u98ce<\/span>\u9669\u3001<\/span>\u89c6\u7f51\u819c<\/span>\u8131\u843d<\/span>\/<\/span>\u6495<\/span>\u88c2<\/span>\u3001\u533b<\/span>\u6e90<\/span>\u6027\u521b \u4f24\u6027\u767d<\/span>\u5185<\/span>\u969c<\/span>\u7b49<\/span>\u3002<\/span><\/p>\n

 <\/span> <\/span><\/p>\n

\u5bf9\u4e8e\u7279\u6b8a\u7ed9\u836f\u9014\u5f84\uff08\u5982\uff1a\u73bb\u7483\u4f53\u5185\u6ce8\u5c04\u6216\u690d\u5165\uff09\u7684\u7814\u7a76\u836f\u7269\uff0c\u5e94\u5c3d\u53ef\u80fd\u5206\u6790\u4e0d\u826f\u4e8b\u4ef6\u3001\u5177\u6709\u4e34\u5e8a\u610f\u4e49\u5b9e\u9a8c\u5ba4\u68c0\u67e5\u5f02\u5e38\u3001\u773c\u79d1\u68c0\u67e5\u5f02\u5e38\u7b49\u7684\u53d1\u751f\u662f\u4e0e\u7814\u7a76\u836f\u7269\u672c\u8eab\u76f8\u5173\u7684\uff0c\u8fd8\u662f\u4e0e\u7ed9\u836f\u64cd\u4f5c\u76f8\u5173\u7684\u3002 \u5bf9\u4e8e\u64cd\u4f5c\u76f8\u5173\u5b89\u5168\u6027\u98ce\u9669\uff0c\u8bd5\u9a8c\u4e2d\u5e94\u5236\u5b9a\u5408\u7406\u7684\u98ce\u9669\u63a7\u5236\u63aa\u65bd\uff0c\u5982\u53c2\u7167\u56fd\u9645\u6216\u56fd\u5185\u76f8\u5173\u6807\u51c6\u5236\u5b9a\u6807\u51c6\u64cd\u4f5c\u6d41\u7a0b\uff0c\u5e76\u57f9\u8bad\u76f8\u5173\u7814\u7a76\u4eba \u5458\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u5e94\u8bb0\u5f55\u4e0d\u826f\u4e8b\u4ef6\u53d1\u751f\u7684\u4e25\u91cd\u7a0b\u5ea6\u3001\u53d1\u751f\u9891\u7387\u3001\u8f6c\u5f52\uff0c\u901a\u8fc7\u8bc4\u4f30\u4e0e\u836f\u7269\u5242\u91cf\u548c\u6cbb\u7597\u6301\u7eed\u65f6\u95f4\u76f8\u5173\u7684\u53d8\u5316\u7b49\u6765\u8bc4\u4f30\u4e0e\u836f\u7269\u7684\u76f8\u5173\u6027\u3002\u7531\u4e8e\u773c\u79d1\u75be\u75c5\u7684\u7279\u6b8a\u6027\uff0c\u5728\u6536\u96c6\u773c\u90e8\u4e0d\u826f\u4e8b\u4ef6\u548c\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\u65f6\u5e94<\/span>\u540c\u65f6\u5305\u62ec\u7814\u7a76\u773c\uff08\u5373\u6839\u636e\u5165\u9009\/\u6392\u9664\u6807\u51c6\u9009\u62e9\u7684\u63a5\u53d7\u7814\u7a76\u6cbb\u7597\u7684\u773c\uff09<\/span>\u548c\u5bf9\u4fa7<\/span>\u773c<\/span>\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u5728\u8ba1\u5212\u957f\u671f\u7ed9\u836f\u7684\u7684\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0c\u5e94\u5efa\u7acb\u4e00\u4e2a\u72ec\u7acb\u7684\u6570\u636e\u76d1\u6d4b\u59d4\u5458\u4f1a\uff08IDMC\uff09\uff0c\u4ee5\u5ba1\u67e5\u7814\u7a76\u671f\u95f4\u62a5\u544a\u7684\u5b89\u5168\u6027\u4e8b\u4ef6\uff08\u5305\u62ec\u8840\u6813\u6813\u585e\u4e8b \u4ef6\uff08\u5fc3\u808c\u6897\u585e\u3001\u4e2d\u98ce\u548c\u8840\u7ba1\u6b7b\u4ea1\uff09\u7b49\uff09\u5e76\u63d0\u4f9b\u5efa\u8bae\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u5bf9\u4e8e\u751f\u7269\u5236\u5242\uff0c\u5e94\u91c7\u7528\u7ecf\u8fc7\u9a8c\u8bc1\u7684\u65b9\u6cd5\u8bc4\u4f30\u836f\u7269\u7684\u514d\u75ab\u539f\u6027\u53cd\u5e94\uff08\u6297\u836f\u6297\u4f53\u7684\u68c0\u6d4b\u7b49\uff09\uff0c\u5e76\u5206\u6790\u514d\u75ab\u539f\u6027\u53cd\u5e94\u5bf9\u836f\u7269 PK\u3001PD\u3001 \u7597\u6548\u548c\u5b89\u5168\u6027\u7684\u5f71\u54cd\u3002<\/span><\/p>\n


<\/span><\/p>\n

3.8  \u8865\u6551\u6cbb\u7597\u4e0e\u5408\u5e76\u7528\u836f<\/span><\/strong><\/p>\n

\u9700\u5728\u7814\u7a76\u65b9\u6848\u9884\u5148\u660e\u786e\u662f\u5426\u5141\u8bb8\u4f7f\u7528\u9488\u5bf9\u75be\u75c5\u4eba\u7fa4\u7684\u8865\u6551\u6cbb\u7597\u3002<\/span>\u5982\u679c\u5141<\/span>\u8bb8<\/span>\u4f7f\u7528<\/span>\uff0c<\/span>\u8fd8\u5e94<\/span>\u5728<\/span>\u65b9\u6848<\/span>\u4e2d<\/span>\u660e\u786e<\/span>\u89c4\u5b9a<\/span>\u5b9e\u65bd\u8865<\/span>\u6551<\/span>\u6cbb\u7597<\/span>\u7684<\/span>\u6807<\/span>\u51c6<\/span>\uff08<\/span>\u5982\u89c6\u529b\u4e0b\u964d\u6216<\/span>\u773c<\/span>\u5e95\u75c5<\/span>\u7076<\/span>\u6d3b\u52a8<\/span>\u7684<\/span>\u60c5\u51b5<\/span>\u7b49<\/span>\uff09<\/span>\u3001<\/span>\u8865<\/span>\u6551<\/span>\u6cbb\u7597\u7684<\/span>\u79cd<\/span>\u7c7b\u548c<\/span>\u7ed9<\/span>\u836f\u65b9<\/span>\u6848<\/span>\u3001<\/span>\u5982<\/span>\u4f55 \u5904\u7406\u63a5<\/span>\u53d7<\/span>\u8865\u6551<\/span>\u6cbb<\/span>\u7597<\/span>\u7684<\/span>\u53d7<\/span>\u8bd5<\/span>\u8005<\/span>\uff08<\/span>\u5982\u7ec8<\/span>\u6b62\u8bd5<\/span>\u9a8c\u6cbb\u7597<\/span>\u6216<\/span>\u9000\u51fa<\/span>\u8bd5<\/span>\u9a8c\u7b49<\/span>\uff09<\/span>\u4ee5<\/span>\u53ca<\/span>\u8be5\u53d7\u8bd5\u8005<\/span>\u7684<\/span>\u8bd5\u9a8c<\/span>\u6570<\/span>\u636e\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\u65b9\u6848\u4e2d\u5e94\u660e\u786e\u662f\u5426\u6709\u5408\u5e76\u6cbb\u7597\uff0c\u5305\u62ec\u7814\u7a76\u773c\u548c\u975e\u7814\u7a76\u773c\u5408\u5e76\u6cbb\u7597 \u7684\u60c5\u51b5\uff0c\u5982\u6709\uff0c\u5e94\u57fa\u4e8e\u836f\u7269\u4f5c\u7528\u7279\u70b9\u7b49\uff0c\u660e\u786e\u5141\u8bb8\u4f7f\u7528\u7684\u6cbb\u7597\u548c\u7981\u6b62\u4f7f\u7528\u7684\u6cbb\u7597\uff0c\u4ee5\u907f\u514d\u5f71\u54cd\u7597\u6548\u548c\u5b89\u5168\u6027\u7684\u8bc4\u4ef7\u3002<\/span><\/p>\n

 <\/span><\/strong><\/p>\n

3.9  \u7edf\u8ba1\u5b66\u8003\u8651<\/span><\/strong><\/p>\n

\u5e94\u53c2\u7167ICH\u76f8\u5173\u6307\u5bfc\u539f\u5219\u8fdb\u884c\u8bbe\u8ba1\u3002<\/span><\/p>\n

\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u6837\u672c\u91cf\u7684\u4f30\u8ba1\u548c\u975e\u52a3\u6548\u754c\u503c\u7684\u8bbe\u8ba1\u4e00\u822c\u6839\u636e\u4e3b\u8981\u7ec8<\/span>\u70b9<\/span>\u6307\u6807<\/span>\u6570<\/span>\u636e\u8fdb<\/span>\u884c<\/span>\u8ba1\u7b97<\/span>\uff0c<\/span>\u53ef\u4ee5<\/span>\u53c2<\/span>\u8003<\/span>\u5df2<\/span>\u53d1\u8868<\/span>\u7684<\/span>\u8d44\u6599<\/span>\u6216<\/span>\u63a2\u7d22<\/span>\u6027<\/span>\u8bd5\u9a8c<\/span>\u7684<\/span>\u7ed3<\/span>\u679c\u3002\u82e5<\/span>\u91c7\u7528<\/span>\u6709<\/span>\u6548\u6027<\/span>\u6307<\/span>\u6807\u8ba1<\/span>\u7b97<\/span>\u6837\u672c<\/span>\u91cf<\/span>\uff0c<\/span>\u5982<\/span>\u91c7\u7528<\/span>\u89c6<\/span>\u7f51\u819c<\/span>\u5f62<\/span>\u6001\u5b66<\/span>\u6539<\/span>\u53d8\u7b49<\/span>\u6307<\/span>\u6807<\/span>\u65f6\uff0c<\/span>\u5e94<\/span>\u8bf4\u660e\u8be5<\/span>\u5176<\/span>\u4e0e\u4e3b<\/span>\u8981<\/span>\u7ec8\u70b9<\/span>\u6307<\/span>\u6807\u7684\u5173<\/span>\u7cfb<\/span>\u5e76\u9610<\/span>\u8ff0<\/span>\u4f7f\u7528\u8fd9<\/span>\u6837<\/span>\u7684\u6709<\/span>\u6548<\/span>\u6027\u6307<\/span>\u6807<\/span>\u7684 \u7406\u7531\u3002<\/span><\/p>\n

 <\/span><\/p>\n

\"CDE\u521a\u521a\u53d1\u5e03\uff01\u5173\u4e8e\u516c\u5f00\u5f81\u6c42\u300a\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\u6cbb\u7597\u836f\u7269\u4e34\u5e8a\u7814\u7a76\u6280\u672f\u6307\u5bfc\u539f\u5219\u300b\u610f\u89c1\u7684\u901a\u77e5\"<\/p>\n

\"CDE\u521a\u521a\u53d1\u5e03\uff01\u5173\u4e8e\u516c\u5f00\u5f81\u6c42\u300a\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\u6cbb\u7597\u836f\u7269\u4e34\u5e8a\u7814\u7a76\u6280\u672f\u6307\u5bfc\u539f\u5219\u300b\u610f\u89c1\u7684\u901a\u77e5\"<\/p>\n

\u6765\u6e90\uff1a  \u56fd\u5bb6\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u603b\u5c40\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3<\/em><\/span><\/p>\n


<\/span><\/em><\/p>\n

\n
\n
\n
\n
\"CDE\u521a\u521a\u53d1\u5e03\uff01\u5173\u4e8e\u516c\u5f00\u5f81\u6c42\u300a\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\u6cbb\u7597\u836f\u7269\u4e34\u5e8a\u7814\u7a76\u6280\u672f\u6307\u5bfc\u539f\u5219\u300b\u610f\u89c1\u7684\u901a\u77e5\"<\/p>\n

\n<\/section>\n

\n

<\/span><\/p>\n<\/section>\n<\/section>\n

\n
\n
\"CDE\u521a\u521a\u53d1\u5e03\uff01\u5173\u4e8e\u516c\u5f00\u5f81\u6c42\u300a\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\u6cbb\u7597\u836f\u7269\u4e34\u5e8a\u7814\u7a76\u6280\u672f\u6307\u5bfc\u539f\u5219\u300b\u610f\u89c1\u7684\u901a\u77e5\"<\/section>\n
\n

\u65b0\u836f&\u533b\u7597\u5668\u68b0<\/span><\/p>\n

\u4e00\u7ad9\u5f0f\u7efc\u5408\u670d\u52a1<\/span>CRO<\/span><\/strong><\/p>\n<\/section>\n<\/section>\n

\n
\n
\n
\n
\n

\n<\/section>\n<\/section>\n<\/section>\n

\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

\u4e3a\u8fdb\u4e00\u6b65\u8d2f\u5f7b\u300a\u56fd\u52a1\u9662\u5173\u4e8e\u6539\u9769\u836f\u54c1\u533b\u7597\u5668\u68b0\u5ba1\u8bc4\u5ba1\u6279\u5236\u5ea6\u7684\u610f\u89c1\u300b\uff08\u56fd\u53d1\u30142015\u301544\u53f7\uff09\u548c\u300a\u5173\u4e8e\u6df1\u5316\u5ba1\u8bc4\u5ba1\u6279\u5236\u5ea6 […]<\/p>\n","protected":false},"author":1,"featured_media":62295,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/62294"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=62294"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/62294\/revisions"}],"predecessor-version":[{"id":62304,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/62294\/revisions\/62304"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/62295"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=62294"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=62294"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=62294"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}