{"id":63243,"date":"2018-11-19T01:00:00","date_gmt":"2018-12-07T03:25:44","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/12\/07\/16e3fed4c1\/"},"modified":"2018-12-07T11:25:45","modified_gmt":"2018-12-07T03:25:45","slug":"16e3fed4c1","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/63243\/","title":{"rendered":"\u5f53\u5fc3\uff01\u8fd9 6 \u7c7b\u836f\u4e0d\u5b9c\u4e0e\u67da\u5b50\u540c\u670d"},"content":{"rendered":"
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\u601d\u8003\u9898<\/span><\/strong><\/p>\n


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\u67da\u5b50\u4f5c\u4e3a\u5e38\u89c1\u7684\u6c34\u679c\uff0c\u88ab\u5e7f\u6cdb\u98df\u7528\uff0c\u4f46\u5df2\u6709\u7814\u7a76\u8868\u660e\u67da\u5b50\u4e0e\u67d0\u4e9b\u836f\u7269\u4e4b\u95f4\u5b58\u5728\u7981\u5fcc\uff0c\u4e0d\u80fd\u540c\u670d\u3002<\/p>\n


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\u8fd9\u4e9b\u836f\u7269\u4e3b\u8981\u6709\u54ea\u51e0\u5927\u7c7b\uff1f<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


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\u98df\u7269\u662f\u5982\u4f55\u5f71\u54cd\u836f\u7269\u7597\u6548\u7684\uff1f<\/span><\/strong><\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


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\u53e3\u670d\u7ed9\u836f\u5feb\u6377\u65b9\u4fbf\uff0c\u957f\u671f\u5360\u636e\u4e34\u5e8a\u7528\u836f\u7684\u4e3b\u5bfc\u5730\u4f4d\uff0c\u4f46\u53e3\u670d\u836f\u7269\u9996\u5148\u9700\u88ab\u80c3\u80a0\u9053\u5438\u6536\u624d\u80fd\u8d77\u6548\uff0c\u6b64\u8fc7\u7a0b\u975e\u5e38\u590d\u6742\uff0c\u53d7\u80c3\u80a0\u9053\u73af\u5883\u7b49\u8bf8\u591a\u56e0\u7d20\u5f71\u54cd\u3002<\/p>\n


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\u80c3\u80a0\u9053\u4e2d\u7684\u98df\u7269\u4f1a\u4e5f\u53ef\u80fd\u5bf9\u836f\u7269\u7684\u5438\u6536\u4ea7\u751f\u4e00\u5b9a\u7684\u5f71\u54cd\u4f5c\u7528\uff0c\u751a\u81f3\u5f71\u54cd\u4e34\u5e8a\u7597\u6548\u3002<\/p>\n


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\u98df\u7269\u5bf9\u836f\u7269\u7684\u5f71\u54cd\uff0c\u4e3b\u8981\u96c6\u4e2d\u4e8e\u4ee5\u4e0b\u51e0\u4e2a\u65b9\u9762\u3002<\/p>\n


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1\uff09\u98df\u7269\u6539\u53d8\u836f\u7269\u5438\u6536\u73af\u5883<\/span>\uff1a\u98df\u7269\u53ef\u80fd\u8bf1\u5bfc\u80c3\u80a0\u53d1\u751f\u751f\u7406\u53d8\u5316\uff0c\u6bd4\u5982 pH \u4ee5\u53ca\u80c3\u80a0\u9053\u8fd0\u52a8\uff0c\u4ece\u800c\u5f71\u54cd\u836f\u7269\u7684\u91ca\u653e\u4ee5\u53ca\u5438\u6536\u3002<\/p>\n


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2\uff09\u98df\u7269\u4e0e\u836f\u54c1\u6210\u5206\u76f8\u4e92\u4f5c\u7528<\/span>\uff1a\u836f\u7269\u4e0e\u98df\u7269\u7ed3\u5408\u540e\u4e0d\u80fd\u88ab\u5438\u6536\uff0c\u5982\u55b9\u8bfa\u916e\u7c7b\u6297\u83cc\u836f\u7269\u3001\u56db\u73af\u7d20\u7c7b\u836f\u7269\u4e0e\u542b\u94c1\u6216\u9499\u7684\u98df\u7269\u540c\u670d\u4f1a\u5f62\u6210\u590d\u6742\u7684\u4e0d\u6eb6\u89e3\u7269\u8d28\uff0c\u4ece\u800c\u964d\u4f4e\u836f\u7269\u7684\u751f\u7269\u5229\u7528\u3002<\/p>\n


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\u67da\u5b50\u4e2d\u5bcc\u542b\u7c7b\u80f0\u5c9b\u7d20\u3001\u679c\u80f6\u3001\u7ef4\u751f\u7d20\u3001\u77ff\u7269\u8d28\u6210\u5206\u548c\u7c97\u7ea4\u7ef4\u7b49\u6d3b\u6027\u6210\u5206\u3002<\/p>\n


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\u7814\u7a76\u8868\u660e\uff0c\u6709\u4e9b\u836f\u7269\u4e0e\u67da\u5b50\/\u67da\u5b50\u6c41\uff08\u5c24\u5176\u662f\u897f\u67da\uff09\u540c\u670d\u76f8\u5f53\u4e8e\u6bd2\u836f\uff0c\u8fd9\u662f\u4e3a\u4ec0\u4e48\u5462\uff1f<\/p>\n


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UGT1A3 \u9176\u53c2\u4e0e\u4e86\u8bb8\u591a\u82b3\u70c3\u3001\u78b3\u6c22\u5316\u5408\u7269\u3001\u80fa\u3001\u975e\u753e\u4f53\u7c7b\u6297\u708e\u836f\u7269\u4ee5\u53ca\u4ed6\u6c40\u7c7b\u836f\u7269\u7b49\u7684\u4ee3\u8c22\u6d88\u9664\uff1bUGT2B7 \u662f\u53c2\u4e0e\u836f\u7269\u8461\u8404\u7cd6\u919b\u9178\u5316\u53cd\u5e94\u6700\u591a\u7684\u9176\uff0c\u5305\u62ec\u6297\u764c\u836f\u7269\uff0c\u5409\u975e\u8d1d\u9f50\u7b49\uff0c\u8fd8\u53ef\u4ee5\u7ed3\u5408\u5f88\u591a\u5185\u6e90\u6027\u7269\u8d28\uff0c\u6bd4\u5982\u80c6\u6c41\u9178\u3001\u96c4\u6fc0\u7d20\u3001\u96cc\u6fc0\u7d20\u7b49\u3002<\/p>\n


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\u5f53\u67d0\u4e9b\u7ecf\u8fc7 UGT1A3 \u6216 UGT2B7 \u9176\u4ee3\u8c22\u7684\u836f\u7269\u4e0e\u67da\u5b50\u540c\u670d\u65f6\uff0c\u53ef\u80fd\u4f1a\u5f71\u54cd\u836f\u7269\u7684\u4ee3\u8c22\u4ee5\u53ca\u6392\u6cc4\uff0c\u5f15\u8d77\u8840\u836f\u6d53\u5ea6\u7684\u53d8\u5316\uff0c\u836f\u6548\u968f\u4e4b\u6539\u53d8\uff0c\u5bfc\u81f4\u4e0d\u826f\u53cd\u5e94\u52a0\u91cd\uff0c\u751a\u81f3\u51fa\u73b0\u4e2d\u6bd2\u6216\u4ea7\u751f\u672a\u77e5\u7684\u4e34\u5e8a\u540e\u679c\u3002<\/p>\n


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\u67da\u5b50\u4e0e\u54ea\u4e9b\u836f\u7269\u5b58\u5728\u7981\u5fcc\uff1f<\/span><\/strong><\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


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\u51fa\u4e8e\u5408\u7406\u5b89\u5168\u7528\u836f\u7684\u8003\u8651\uff0c\u4e0b\u9762\u4ecb\u7ecd\u4e00\u4e0b\u4e0e\u67da\u5b50\u5b58\u5728\u7981\u5fcc\u7684\u836f\u7269\uff0c\u4ee5\u671f\u4e3a\u5927\u5bb6\u63d0\u4f9b\u4e00\u4e9b\u65e5\u5e38\u77e5\u8bc6\u3002<\/p>\n


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1. \u964d\u538b\u836f<\/span><\/strong><\/p>\n


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2. \u964d\u8102\u836f\u7269<\/span><\/strong><\/p>\n


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\u67da\u5b50\u53ef\u6291\u5236\u4ee3\u8c22\u4ed6\u6c40\u7c7b\u836f\u7269\u7684\u4ee3\u8c22\u9176\uff0c\u8f9b\u4f10\u4ed6\u6c40\uff08\u70b9\u6b64\u67e5\u770b\u8f9b\u4f10\u4ed6\u6c40\u8be6\u7ec6\u8bf4\u660e\u4e66<\/a>\uff09\u7b49\u4e0e\u67da\u5b50\u540c\u670d\uff0c\u4f1a\u5bfc\u81f4\u836f\u7269\u5728\u4f53\u5185\u84c4\u79ef\uff0c\u589e\u52a0\u809d\u635f\u4f24\u51e0\u7387\u3001\u6a2a\u7eb9\u808c\u6eb6\u89e3\u7b49\u4e0d\u826f\u53cd\u5e94\u7684\u53d1\u751f\u98ce\u9669\uff0c\u751a\u81f3\u5f15\u8d77\u80be\u8870\u7aed\u3002<\/p>\n


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3. \u5b89\u7720\u836f<\/span><\/strong><\/p>\n


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\u67da\u5b50\u4f1a\u5ef6\u957f\u5730\u897f\u6cee\u3001\u54aa\u8fbe\u5511\u4ed1\u7b49\u5b89\u7720\u836f\u7269\u7684\u4ee3\u8c22\uff0c\u5ef6\u957f\u5176\u5728\u4f53\u5185\u7684\u505c\u7559\u65f6\u95f4\uff0c\u52a0\u91cd\u55dc\u7761\u3001\u5934\u6655\u7b49\u540e\u9057\u75c7\u72b6\uff0c\u5bfc\u81f4\u670d\u7528\u7b2c\u4e8c\u5929\u51fa\u73b0\u300c\u5bbf\u9189\u300d\u73b0\u8c61\uff0c\u5bf9\u4e8e\u53f8\u673a\u548c\u9ad8\u5371\u7cbe\u5bc6\u64cd\u4f5c\u7684\u4eba\u7fa4\u5c24\u9700\u6ce8\u610f\u3002<\/p>\n


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4. \u907f\u5b55\u836f<\/span><\/strong><\/p>\n


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\u67da\u5b50\u4f1a\u963b\u788d\u5973\u6027\u5bf9\u907f\u5b55\u836f\u7684\u5438\u6536\u548c\u5229\u7528\uff0c\u56e0\u6b64\u670d\u7528\u836f\u7269\u671f\u95f4\u5403\u67da\u5b50\u53ef\u80fd\u4f1a\u5bfc\u81f4\u907f\u5b55\u5931\u8d25\u3002<\/p>\n


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5. \u6297\u8fc7\u654f\u836f\u7269<\/span><\/strong><\/p>\n


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\u67da\u5b50\u80fd\u8bf1\u53d1\u7279\u975e\u90a3\u5b9a\u7b49\u6297\u8fc7\u654f\u836f\u7269\u7684\u4e0d\u826f\u53cd\u5e94\uff0c\u5bfc\u81f4\u5934\u6655\u3001\u5fc3\u60b8\u3001\u5fc3\u5f8b\u5931\u5e38\u7b49\u75c7\u72b6\u3002<\/p>\n


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6. \u7279\u522b\u6ce8\u610f\u4e8b\u9879<\/span><\/strong><\/p>\n


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\u8fd8\u6709\u7814\u7a76\u53d1\u73b0\uff0c\u67da\u5b50\u4e0e\u514d\u75ab\u6291\u5236\u5242\uff08\u5982\u73af\u5b62\u7d20\uff09\u4e4b\u95f4\uff0c\u4e5f\u5b58\u5728\u7981\u5fcc\u3002<\/p>\n


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\u4e0d\u540c\u7684\u4eba\u5bf9\u67da\u5b50\u7684\u53cd\u5e94\u4e0d\u540c\u3002<\/p>\n


<\/p>\n

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\u5c0f\u63d0\u793a<\/span><\/strong><\/p>\n


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\u756a\u8304\u3001\u8461\u8404\u67da\u3001\u6a59\u5b50\u4ee5\u53ca\u67d1\u6a58\u7b49\u82b8\u9999\u79d1\u690d\u7269\u7684\u679c\u5b9e\u3001\u679c\u76ae\u90e8\u4f4d\u5747\u542b\u6709\u6a59\u76ae\u7d20\u6216\u8005\u67da\u76ae\u7d20\uff0c\u4f1a\u5f71\u54cd\u4eba\u4f53\u5185\u7684\u4ee3\u8c22\u9176\uff0c\u4ece\u800c\u5f71\u54cd\u836f\u7269\u7684\u4ee3\u8c22\u548c\u6392\u6cc4\uff0c\u6240\u4ee5\u5728\u65e5\u5e38\u751f\u6d3b\u4e2d\u670d\u7528\u836f\u7269\u7684\u65f6\u5019\u4e00\u5b9a\u8981\u6ce8\u610f\u4e0e\u8fd9\u4e9b\u6c34\u679c\u4e4b\u95f4\u7684\u76f8\u4e92\u4f5c\u7528\u3002<\/p>\n


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\u63a8\u8350\u9605\u8bfb\uff1a<\/span><\/strong><\/span><\/p>\n


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MRI \u5165\u95e8\uff1a\u5982\u4f55\u9605\u7247<\/a>
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\u559d\u9152\u517b\u751f\uff1f\u4e0d\u5b58\u5728\u7684\uff0c\u4e00\u6ef4\u9152\u4e5f\u4f1a\u9020\u6210\u635f\u4f24<\/a>
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\u5feb\u901f\u95ee\u7b54 11\uff1a\u591c\u95f4\u6613\u9192<\/a>
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\u9996\u53d1 | \u4e34\u5e8a\u7528\u836f<\/span><\/span><\/p>\n

\u4f5c\u8005 | <\/span>\u9102\u5c14\u591a\u65af\u5e02\u4e2d\u5fc3\u533b\u9662\uff08\u5eb7\u5df4\u4ec0\u90e8\uff09\u7530\u96ea\u6885 <\/span><\/span><\/p>\n

\u7f16\u8f91 | \u9f9a\u73e0\u840d \u738b\u5f18<\/span>
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\u6295\u7a3f\u53ca\u5408\u4f5c | wanghong@dxy.cn<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u9898\u56fe\u6765\u6e90 | \u7ad9\u9177\u6d77\u6d1b<\/span><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

\"\u5f53\u5fc3\uff01\u8fd9<\/p>\n

<\/span><\/p>\n<\/section>\n<\/section>\n

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\u53c2\u8003\u8d44\u6599<\/span><\/strong><\/p>\n

[1] \u9648\u79cb\u590f. \u6211\u56fd\u67da\u7c7b\u53ca\u5176\u7814\u7a76\u6982\u51b5 [J]. \u798f\u5efa\u679c\u6811,2004,(4):6-9.<\/span><\/p>\n


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[2]Laura Giamperi,Daniele Fraternale,Anahi Bucchini,Donata Ricci. Antioxidant activity of Citrus paradisi seeds glyceric extract[J]. Fitoterapia,2003(2).<\/span><\/p>\n


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[3]Shela Gorinstein,Milena Cvikrov\u00e1,Ivana Machackova, Ratiporn Haruenkit,Yong-Seo Park,Soon-Teck Jung,Kazutaka Yamamoto,Alma Leticia Martinez Ayala,Elena Katrich,Simon Trakhtenberg. Characterization of antioxidant compoundds in Jaffa sweeties and white grapefruits[J]. Food Chemistry,2004(4).<\/span><\/p>\n


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[6] \u8bb8\u667a\u9896\uff0c\u9ec4\u82b3\uff0c\u65b9\u60a6\uff0e\u5f71\u54cd\u53e3\u670d\u836f\u7269\u5438\u6536\u7684\u56e0\u7d20\u63a2\u8ba8 [J]. \u6d77\u5ce1\u836f\u5b66\uff0c2016\uff0c28( 6) : 248-249.<\/span><\/p>\n


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[7]Fang Z Z, Wang H, Cao Y F, et al. Enantioselective inhibition of carprofen towards UDP-glucuronosyltransferase (UGT) 2B7.[J]. Chirality, 2015, 27(3):189\u2013193.<\/span><\/p>\n<\/section>\n<\/section><\/div>\n","protected":false},"excerpt":{"rendered":"

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