{"id":64629,"date":"2018-12-01T01:00:00","date_gmt":"2018-12-07T03:40:50","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/12\/07\/e1c9f21cd3\/"},"modified":"2018-12-07T11:40:51","modified_gmt":"2018-12-07T03:40:51","slug":"e1c9f21cd3","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/64629\/","title":{"rendered":"\u3010\u58f9\u5468\u836f\u8baf\u3011\u300a\u4e2d\u534e\u4eba\u6c11\u5171\u548c\u56fd\u836f\u54c1\u7ba1\u7406\u6cd5\uff08\u4fee\u6b63\u8349\u6848\uff09\u300b\u53d1\u5e03\u5e76\u5411\u5168\u793e\u4f1a\u5f81\u6c42\u610f\u89c1\uff01\u536b\u5065\u59d4\u53d1\u6587\u8981\u6c42\u5efa\u7acb\u957f\u671f\u5904\u65b9\u673a\u5236\uff01"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;line-height: 25.6px;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-top: 3px;padding-bottom: 3px;max-width: 100%;box-sizing: border-box;display: inline-block;border-top: 1px solid rgb(224, 224, 224);border-right-color: rgb(224, 224, 224);border-bottom: 1px solid rgb(224, 224, 224);border-left-color: rgb(224, 224, 224);overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-right: 5px;padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(1, 26, 65);overflow-wrap: break-word !important;\">\n<p style=\"text-align: center;\"><img class=\"\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/0-1544154051.jpeg\" alt=\"\u3010\u58f9\u5468\u836f\u8baf\u3011\u300a\u4e2d\u534e\u4eba\u6c11\u5171\u548c\u56fd\u836f\u54c1\u7ba1\u7406\u6cd5\uff08\u4fee\u6b63\u8349\u6848\uff09\u300b\u53d1\u5e03\u5e76\u5411\u5168\u793e\u4f1a\u5f81\u6c42\u610f\u89c1\uff01\u536b\u5065\u59d4\u53d1\u6587\u8981\u6c42\u5efa\u7acb\u957f\u671f\u5904\u65b9\u673a\u5236\uff01\" title=\"\u3010\u58f9\u5468\u836f\u8baf\u3011\u300a\u4e2d\u534e\u4eba\u6c11\u5171\u548c\u56fd\u836f\u54c1\u7ba1\u7406\u6cd5\uff08\u4fee\u6b63\u8349\u6848\uff09\u300b\u53d1\u5e03\u5e76\u5411\u5168\u793e\u4f1a\u5f81\u6c42\u610f\u89c1\uff01\u536b\u5065\u59d4\u53d1\u6587\u8981\u6c42\u5efa\u7acb\u957f\u671f\u5904\u65b9\u673a\u5236\uff01\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;line-height: 25.6px;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-top: 3px;padding-bottom: 3px;max-width: 100%;box-sizing: border-box;display: inline-block;border-top: 1px solid rgb(224, 224, 224);border-right-color: rgb(224, 224, 224);border-bottom: 1px solid rgb(224, 224, 224);border-left-color: rgb(224, 224, 224);overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-right: 5px;padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(1, 26, 65);overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;font-size: 20px;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 25.6px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u672c\u5468\u89c6\u70b9<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"white-space: normal;max-width: 100%;line-height: 25.6px;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;box-sizing: border-box;background-color: rgb(239, 239, 239);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"margin-top: 5px;margin-bottom: 20px;max-width: 100%;min-height: 1em;line-height: 2em;text-align: justify;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;line-height: 27px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong>\u3010\u300a\u836f\u54c1\u7ba1\u7406\u6cd5\uff08\u4fee\u6b63\u8349\u6848\uff09\u300b\u89e3\u8bfb\u3011\u63d0\u9ad8\u8fdd\u6cd5\u6210\u672c \u4fdd\u969c\u7528\u836f\u5b89\u5168<\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/p>\n<p style=\"margin-top: 5px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;text-align: justify;font-size: 14px;line-height: 2em;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"font-family: &quot;Helvetica Neue&quot;, Helvetica, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\">2018\u5e7411\u6708\uff0c\u300a\u4e2d\u534e\u4eba\u6c11\u5171\u548c\u56fd\u836f\u54c1\u7ba1\u7406\u6cd5\uff08\u4fee\u6b63\u8349\u6848\uff09\u300b\uff08\u4ee5\u4e0b\u7b80\u79f0\u201c\u8349\u6848\u201d\uff09\u53d1\u5e03\u5e76\u5411\u5168\u793e\u4f1a\u5f81\u6c42\u610f\u89c1\u3002\u672c\u6b21\u8349\u6848\u6d89\u53ca\u7684\u4fee\u6539\u5185\u5bb9\u4e3b\u8981\u6db5\u76d6\u4e86\u836f\u54c1\u5168\u7a0b\u76d1\u7ba1\u5236\u5ea6\u3001\u8fdd\u6cd5\u884c\u4e3a\u7684\u6cd5\u5f8b\u8d23\u4efb\u3001\u836f\u54c1\u4e0a\u5e02\u8bb8\u53ef\u6301\u6709\u4eba\u5236\u5ea6\u3001\u836f\u54c1\u5ba1\u6279\u5236\u5ea6\u7b49\u95ee\u9898\u3002\u5176\u4e2d\uff0c\u5bf9\u6cd5\u5f8b\u8d23\u4efb\u90e8\u5206\u7684\u4fee\u6539\u8d85\u8fc7\u6b64\u6b21\u4fee\u6539\u90e8\u5206\u7684\u4e09\u5206\u4e4b\u4e00\u3002\u7b14\u8005\u5728\u6b64\u505a\u4e00\u4e2a\u7b80\u8981\u7684\u4eae\u70b9\u89e3\u8bfb\u3002<\/span><span style=\"letter-spacing: 0.544px;\">\uff08\u8be6\u89c1\u4e0b\u65b9\u9605\u8bfb\u539f\u6587\uff09<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\" style=\"margin-top: -4px;max-width: 100%;box-sizing: border-box;width: 556px;text-align: right;overflow-wrap: break-word !important;\">\n<section style=\"margin-left: auto;max-width: 100%;box-sizing: border-box;width: 50px;height: 4px;background-color: rgb(1, 26, 65);overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section  label=\"Powered by 135editor.com\" style=\"white-space: normal;max-width: 100%;line-height: 25.6px;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;line-height: 25.6px;overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-top: 3px;padding-bottom: 3px;max-width: 100%;box-sizing: border-box;display: inline-block;border-top: 1px solid rgb(224, 224, 224);border-right-color: rgb(224, 224, 224);border-bottom: 1px solid rgb(224, 224, 224);border-left-color: rgb(224, 224, 224);overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-right: 5px;padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(1, 26, 65);overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><strong style=\"font-size: 20px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u653f\u7b56\u52a8\u5411<\/strong><br  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"white-space: normal;max-width: 100%;line-height: 25.6px;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;box-sizing: border-box;background-color: rgb(239, 239, 239);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\"><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">1.&nbsp; <\/span><\/strong><\/strong><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u536b\u5065\u59d4\u53d1\u6587\u8981\u6c42\u5efa\u7acb\u957f\u671f\u5904\u65b9\u673a\u5236<\/span><\/strong><\/strong><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\">11\u670826\u65e5\uff0c\u56fd\u5bb6\u536b\u5065\u59d4\u53d1\u5e03\u4e86\u300a\u5173\u4e8e\u52a0\u5feb\u836f\u5b66\u670d\u52a1\u9ad8\u8d28\u91cf\u53d1\u5c55\u7684\u610f\u89c1\u300b\uff08\u4ee5\u4e0b\u7b80\u79f0\u300a\u610f\u89c1\u300b\uff09\uff0c\u660e\u786e\u6307\u51fa\u8981\u63a2\u7d22\u6162\u6027\u75c5\u957f\u671f\u5904\u65b9\u7ba1\u7406\u3002\u300a\u610f\u89c1\u300b\u6307\u51fa\uff0c\u201c\u9f13\u52b1\u5404\u7ea7\u536b\u751f\u5065\u5eb7\u884c\u653f\u90e8\u95e8\u5546\u533b\u4fdd\u90e8\u95e8\u5236\u8ba2\u51fa\u53f0\u6162\u6027\u75c5\u957f\u671f\u5904\u65b9\u7ba1\u7406\u653f\u7b56\uff0c\u660e\u786e\u53ef\u5f00\u5177\u957f\u671f\u5904\u65b9\u7684\u6162\u6027\u75c5\u76ee\u5f55\u3001\u7528\u836f\u8303\u56f4\u3001\u7ba1\u7406\u5236\u5ea6\u3001\u5b89\u5168\u544a\u77e5\u7b49\u8981\u6c42\uff0c\u5bf9\u8bc4\u4f30\u540e\u7b26\u5408\u8981\u6c42\u7684\u6162\u6027\u75c5\u60a3\u8005\uff0c\u4e00\u6b21\u53ef\u5f00\u517712\u5468\u4ee5\u5185\u76f8\u5173\u836f\u54c1\u3002\u201d<span style=\"color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 14px;letter-spacing: 0.544px;text-align: justify;background-color: rgb(239, 239, 239);\">\uff08\u8be6\u89c1\u4e0b\u65b9\u9605\u8bfb\u539f\u6587\uff09<\/span><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\"><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">2.&nbsp; <\/span><\/strong><\/strong><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u533b\u7597\u5668\u68b0\u4e0a\u5e02\u8def\u5f84\u8981\u7b80\u5316\uff1f\u7f8eFDA\u5c06\u5927\u5e45\u4fee\u6539510(k)\u6cd5\u89c4<\/span><\/strong><\/strong><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\">2018\u5e7411\u670826\u65e5\uff0c\u7f8e\u56fdFDA\u5c40\u957fScott Gottlieb\u535a\u58eb\u548c\u8bbe\u5907\u4e0e\u653e\u5c04\u5065\u5eb7\u4e2d\u5fc3\u4e3b\u4efbJeffrey Shuren\u535a\u58eb\u5ba3\u5e03\uff0cFDA\u6b63\u8ba1\u5212\u5bf9510\uff08k\uff09\u6d41\u7a0b\u6309\u73b0\u9636\u6bb5\u7684\u5b9e\u9645\u60c5\u51b5\u8fdb\u884c\u4fee\u6b63\u3002\u4e8c\u4eba\u5728\u5173\u4e8eFDA 510\uff08k\uff09\u8ba1\u5212\u73b0\u4ee3\u5316\u6539\u9769\u65b0\u6b65\u9aa4\u7684\u58f0\u660e\u4e2d\u63d0\u5230\uff0c\u6b64\u6b21\u63a8\u8fdb\u5bf9\u533b\u7597\u5668\u68b0\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u7684\u5ba1\u67e5\u58f0\u660e\uff0c\u4e3b\u8981\u4fa7\u91cd\u4e8e\u786e\u4fdd\u901a\u8fc7510\uff08k\uff09\u6d41\u7a0b\u7684\u65b0\u8bbe\u5907\u80fd\u591f\u7b26\u5408\u4e0d\u65ad\u53d1\u5c55\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u6807\u51c6\u3002<span style=\"color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;\">\uff08\u8be6\u89c1\u4e0b\u65b9\u9605\u8bfb\u539f\u6587\uff09<\/span><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\"><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">3.&nbsp; <\/span><\/strong><\/strong><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u6700\u65b0\u5e26\u91cf\u91c7\u8d2d\uff1a\u539f\u7814\u836f\u4e0d\u964d\u4ef7\u5c31\u51fa\u5c40<\/span><\/strong><\/strong><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\">11\u670826\u65e5\uff0c\u5b89\u5fbd\u4eb3\u5dde\u5e02\u6df1\u5316\u533b\u6539\u7ec4\u3001\u4eb3\u5dde\u5e02\u536b\u8ba1\u59d4\u7b49\u4e94\u90e8\u95e8\u8054\u5408\u5370\u53d1\u300a\u5173\u4e8e\u5370\u53d1\u4eb3\u5dde\u5e02\u516c\u7acb\u533b\u7597\u673a\u6784\u836f\u54c1\u96c6\u4e2d\u5e26\u91cf\u91c7\u8d2d\u5de5\u4f5c\u65b9\u6848\u7684\u901a\u77e5\u300b\uff08\u4ee5\u4e0b\u7b80\u79f0\u300a\u901a\u77e5\u300b\uff09\u3002\u300a\u901a\u77e5\u300b\u663e\u793a\uff0c\u6b64\u6b21\u5e26\u91cf\u91c7\u8d2d\u7684\u6307\u5bfc\u601d\u60f3\uff0c\u5c31\u662f\u4fdd\u8bc1\u836f\u54c1\u4f9b\u5e94\u548c\u8d28\u91cf\u3002<span style=\"color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;\">\uff08\u8be6\u89c1\u4e0b\u65b9\u9605\u8bfb\u539f\u6587\uff09<\/span><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\"><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">4.&nbsp;<\/span><\/strong><\/strong><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u56fd\u5bb6\u536b\u5065\u59d4\u53d1\u6587\u7981\u6b62\u836f\u623f\u6258\u7ba1\uff01<\/span><\/strong><\/strong><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\">11\u670826\u65e5\uff0c\u56fd\u5bb6\u536b\u5065\u59d4\u3001\u56fd\u5bb6\u4e2d\u533b\u836f\u7ba1\u7406\u5c40\u8054\u5408\u4e0b\u53d1\u300a\u5173\u4e8e\u52a0\u5feb\u836f\u5b66\u670d\u52a1\u9ad8\u8d28\u91cf\u53d1\u5c55\u7684\u610f\u89c1\u300b\uff08\u4ee5\u4e0b\u7b80\u79f0\u300a\u610f\u89c1\u300b\uff09\u3002\u9488\u5bf9\u5f53\u524d\u5b58\u5728\u7684\u95ee\u9898\uff0c\u300a\u610f\u89c1\u300b\u4ece5\u4e2a\u65b9\u9762\u63d0\u51fa\u4e8614\u9879\u8981\u6c42\uff0c\u4fc3\u8fdb\u836f\u5b66\u670d\u52a1\u7684\u9ad8\u8d28\u91cf\u53d1\u5c55\u3002\u5176\u4e2d\uff0c\u5728\u201c\u52a0\u5f3a\u836f\u5b66\u90e8\u95e8\u5efa\u8bbe\u201d\u65b9\u9762\u660e\u786e\u63d0\u5230\uff1a\u8fd9\u662f\u9996\u6b21\u4ece\u56fd\u5bb6\u5c42\u9762\u4e0a\u63d0\u51fa\uff0c\u7981\u6b62\u533b\u9662\u836f\u623f\u6258\u7ba1\u3002<span style=\"letter-spacing: 0.544px;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\">\uff08\u8be6\u89c1\u4e0b\u65b9\u9605\u8bfb\u539f\u6587\uff09<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\" style=\"margin-top: -4px;max-width: 100%;box-sizing: border-box;width: 556px;text-align: right;overflow-wrap: break-word !important;\">\n<section style=\"margin-left: auto;max-width: 100%;box-sizing: border-box;width: 50px;height: 4px;background-color: rgb(1, 26, 65);overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<section style=\"margin-left: auto;max-width: 100%;box-sizing: border-box;width: 50px;height: 4px;background-color: rgb(1, 26, 65);overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;line-height: 25.6px;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-top: 3px;padding-bottom: 3px;max-width: 100%;box-sizing: border-box;display: inline-block;border-top: 1px solid rgb(224, 224, 224);border-right-color: rgb(224, 224, 224);border-bottom: 1px solid rgb(224, 224, 224);border-left-color: rgb(224, 224, 224);overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-right: 5px;padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(1, 26, 65);overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 20px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u4f01\u4e1a\u52a8\u6001<\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"white-space: normal;max-width: 100%;line-height: 25.6px;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;box-sizing: border-box;background-color: rgb(239, 239, 239);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\"><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">1.&nbsp;&nbsp;<\/span><\/strong><\/strong><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u57fa\u56e0\u6cf0\u514b\u6536\u8d2dJecure \u83b7\u5f97\u6574\u4e2aNLRP3\u6291\u5236\u5242\u4ea7\u54c1\u7ebf<\/span><\/strong><\/strong><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\">\u65e5\u524d\uff0c\u7f57\u6c0f\u96c6\u56e2\u65d7\u4e0bGenentech\uff08\u57fa\u56e0\u6cf0\u514b\uff09\u5ba3\u5e03\u5bf9Jecure Therapeutics\u8fdb\u884c\u6536\u8d2d\u3002Jecure\u662f\u4e00\u5bb6\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u62e5\u6709\u9488\u5bf9\u4e25\u91cd\u708e\u75c7\u6027\u75be\u75c5\u7684\u65b0\u578b\u836f\u7269\u7684\u7814\u53d1\u8ba1\u5212\u3002\u901a\u8fc7\u6b64\u6b21\u6536\u8d2d\uff0c\u57fa\u56e0\u6cf0\u514b\u5c06\u83b7\u5f97Jecure\u516c\u53f8\u6574\u4e2aNLRP3\u6291\u5236\u5242\u4e34\u5e8a\u524d\u7ec4\u5408\u4ea7\u54c1\u7ebf\u7684\u5168\u90e8\u6743\u5229\u3002<span style=\"color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;\">\uff08\u8be6\u89c1\u4e0b\u65b9\u9605\u8bfb\u539f\u6587\uff09<\/span><br  \/><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\"><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">2.&nbsp;<\/span><\/strong><\/strong>&nbsp;<strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong>\u5b89\u65af\u6cf0\u6765\u4e0eJuventas\u8fbe\u6210\u5168\u7403\u6218\u7565\u5408\u4f5c<\/strong><\/span><\/strong><\/strong><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\">\u65e5\u672c\u836f\u4f01\u5b89\u65af\u6cf0\u6765\uff08Astellas\uff09\u8fd1\u65e5\u5ba3\u5e03\u4e0eJuventas Therapeutics\u516c\u53f8\u5c31\u540e\u8005\u5f00\u53d1\u7684\u57fa\u56e0\u7597\u6cd5JVS-100\u8fbe\u6210\u4e86\u4e00\u9879\u72ec\u5bb6\u5168\u7403\uff08\u4e0d\u5305\u62ec\u4e2d\u56fd\uff09\u9009\u62e9\u548c\u6388\u6743\u534f\u8bae\u3002JVS-100\u662f\u4e00\u79cd\u975e\u75c5\u6bd2\u6027\u57fa\u56e0\u7597\u6cd5\uff0c\u53ef\u8868\u8fbe\u57fa\u8d28\u7ec6\u80de\u884d\u751f\u56e0\u5b50-1\uff08SDF-1\uff09\uff0cSDF-1\u662f\u4e00\u79cd\u5929\u7136\u5b58\u5728\u7684\u4fe1\u53f7\u86cb\u767d\uff0c\u53ef\u6fc0\u6d3b\u5185\u6e90\u6027\u7ec4\u7ec7\u4fee\u590d\u4fe1\u53f7\u4f20\u5bfc\u901a\u8def\u3002<span style=\"color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;\">\uff08\u8be6\u89c1\u4e0b\u65b9\u9605\u8bfb\u539f\u6587\uff09<\/span><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\"><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">3.&nbsp; <\/span><\/strong><\/strong><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">Vineti\u4e0eTessa\u5408\u4f5c\u6269\u5c55\u5b9e\u4f53\u80bf\u7624\u7684\u4e2a\u6027\u5316T\u7ec6\u80de\u7597\u6cd5<\/span><\/strong><\/strong><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\">\u7f8e\u56fd\u5f53\u5730\u65f6\u95f42018\u5e7411\u670822\u65e5\uff0c\u7f8e\u56fd\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u4e2a\u6027\u5316\u6cbb\u7597\u7684\u9886\u5148\u6570\u5b57\u8bb0\u5f55\u5e73\u53f0Vineti\u5ba3\u5e03\uff0c\u4e0eTessa Therapeutics\u7b7e\u8ba2\u5408\u4f5c\u534f\u8bae\uff0c\u5728\u4e16\u754c\u8303\u56f4\u5185\u63a8\u8fdb\u548c\u6269\u5c55\u5b9e\u4f53\u80bf\u7624\u7684\u4e2a\u6027\u5316\u7ec6\u80de\u7597\u6cd5\u3002<span style=\"color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;\">\uff08\u8be6\u89c1\u4e0b\u65b9\u9605\u8bfb\u539f\u6587\uff09<\/span><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\"><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">4.&nbsp;&nbsp;<\/span><\/strong><\/strong><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u4e13\u6ce8\u201c\u6e10\u51bb\u4eba\u75c7\u201d\u7b49\u75be\u75c5\u9886\u57df \u91d1\u7968\u5956\u65b0\u9510\u83b7550\u4e07\u7f8e\u5143\u79cd\u5b50\u8f6e\u878d\u8d44<\/span><\/strong><\/strong><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\">\u521d\u521b\u516c\u53f8QurAlis\u8fd1\u65e5\u5ba3\u5e03\uff0c\u5b8c\u6210550\u4e07\u7f8e\u5143\u7684\u79cd\u5b50\u8f6e\u878d\u8d44\u3002QurAlis\u6253\u7b97\u5229\u7528\u8fd9\u7b14\u8d44\u91d1\u63a8\u8fdb\u808c\u840e\u7f29\u4fa7\u7d22\u786c\u5316\u75c7\uff08ALS\uff09\u548c\u989d\u989e\u53f6\u75f4\u5446\uff08FTD\uff09\u7684\u4e34\u5e8a\u524d\u671f\u7814\u7a76\u3002<span style=\"color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;\">\uff08\u8be6\u89c1\u4e0b\u65b9\u9605\u8bfb\u539f\u6587\uff09<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\" style=\"margin-top: -4px;max-width: 100%;box-sizing: border-box;width: 556px;text-align: right;overflow-wrap: break-word !important;\">\n<section style=\"margin-left: auto;max-width: 100%;box-sizing: border-box;width: 50px;height: 4px;background-color: rgb(1, 26, 65);overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<section style=\"margin-left: auto;max-width: 100%;box-sizing: border-box;width: 50px;height: 4px;background-color: rgb(1, 26, 65);overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;line-height: 25.6px;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-top: 3px;padding-bottom: 3px;max-width: 100%;box-sizing: border-box;display: inline-block;border-top: 1px solid rgb(224, 224, 224);border-right-color: rgb(224, 224, 224);border-bottom: 1px solid rgb(224, 224, 224);border-left-color: rgb(224, 224, 224);overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-right: 5px;padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(1, 26, 65);overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 20px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u836f\u8baf\u5feb\u9012<\/strong><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"white-space: normal;max-width: 100%;line-height: 25.6px;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;box-sizing: border-box;background-color: rgb(239, 239, 239);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\"><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">1.&nbsp;<\/span><\/strong><\/strong><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">FDA\u6279\u51c6\u9996\u6b3e\u5229\u59a5\u6614\u5355\u6297\u751f\u7269\u7c7b\u4f3c\u836f \u7528\u4e8e\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624<\/span><\/strong><\/strong><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\">\u65e5\u524d\uff0c\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40\uff08FDA\uff09\u6279\u51c6\u4e86\u97e9\u56fd\u836f\u4f01trion Healthcare\u7684\u751f\u7269\u4eff\u5236\u836fTruxima\uff08rituximab-abbs\uff09\uff0c\u4f5c\u4e3a\u6cbb\u7597\u6210\u4ebaCD20\u9633\u6027\u3001B\u7ec6\u80de\u975e\u970d\u5947\u91d1\u6dcb\u5df4\u7624\uff08NHL\uff09\u7684\u5355\u72ec\u4f7f\u7528\u836f\u7269\u6216\u4e0e\u5316\u7597\u8054\u5408\u4f7f\u7528\u3002<span style=\"max-width: 100%;line-height: 27px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\uff08\u8be6\u89c1\u4e0b\u65b9\u9605\u8bfb<\/span><span style=\"max-width: 100%;line-height: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u539f\u6587\uff09<\/span><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\"><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">2.&nbsp; <\/span><\/strong><\/strong><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">FDA\u5feb\u901f\u901a\u9053\u8ba4\u5b9a\uff1a\u57fa\u56e0\u7597\u6cd5\u6cbb\u7597\u7f55\u89c1\u8d2b\u8840 \u62ef\u6551\u9aa8\u9ad3\u8870\u7aed<\/span><\/strong><\/strong><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\">11\u670827\u65e5\uff0c\u7f8e\u56fd\u591a\u5e73\u53f0\u57fa\u56e0\u7597\u6cd5\u516c\u53f8Rocket Pharmaceuticals\u8868\u793a\uff0c\u516c\u53f8\u65d7\u4e0b\u57fa\u4e8e\u6162\u75c5\u6bd2\u8f7d\u4f53\uff08LVV\uff09\u7528\u4e8e\u8303\u53ef\u5c3c\u8d2b\u8840\uff08FA\uff09\u6cbb\u7597\u7684\u57fa\u56e0\u7597\u6cd5RP-L102\u83b7\u5f97\u4e86\u7f8e\u56fdFDA\u518d\u751f\u533b\u5b66\u5148\u8fdb\u7597\u6cd5\uff08RMAT*\uff09\u4ee5\u53ca\u5feb\u901f\u901a\u9053\u8ba4\u5b9a\u3002RMAT\u662f\u6839\u636eRP-L102\u5728\u6b27\u6d32\u8fdb\u884c\u76841\/2\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u79ef\u6781\u7597\u6548\u548c\u5b89\u5168\u6027\u7ed3\u679c\u800c\u6388\u4e88\u7684\u3002<span style=\"max-width: 100%;line-height: 27px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\uff08\u8be6\u89c1\u4e0b\u65b9\u9605\u8bfb<\/span><span style=\"max-width: 100%;line-height: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u539f\u6587\uff09<\/span><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\"><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">3.&nbsp;<\/span><\/strong><\/strong><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u7834\u7eaa\u5f55\uff01FDA\u521a\u521a\u6279\u51c6\u4eca\u5e74\u7b2c54\u6b3e\u65b0\u836f\u4e0a\u5e02<\/span><\/strong><\/strong><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\">\u8fd1\u65e5\uff0c\u7f8e\u56fdFDA\u5ba3\u5e03\uff0c\u6279\u51c6\u5b89\u65af\u6cf0\u6765\uff08Astellas Pharma\uff09\u516c\u53f8\u7684Xospata\uff08gilteritinib\uff09\u4e0a\u5e02\uff0c\u7528\u4e8e\u6cbb\u7597\u643a\u5e26FLT3\u57fa\u56e0\u7a81\u53d8\u7684\u590d\u53d1\/\u96be\u6cbb\u6027\u6025\u6027\u9aa8\u9ad3\u6027\u767d\u8840\u75c5\uff08AML\uff09\u6210\u4eba\u60a3\u8005\uff08\u7ea6\u5360\u60a3\u8005\u603b\u6570\u7684\u4e09\u5206\u4e4b\u4e00\uff09\u3002\u8fd9\u4e9b\u60a3\u8005\u7684\u57fa\u56e0\u7a81\u53d8\u9700\u8981\u88abFDA\u6279\u51c6\u7684\u4f34\u968f\u8bca\u65ad\u786e\u8ba4\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u8fd9\u662f\u7f8e\u56fdFDA\u4eca\u5e74\u6279\u51c6\u7684\u7b2c54\u6b3e\u65b0\u836f\uff0c\u6253\u7834\u4e86FDA\u5e74\u5ea6\u6279\u51c6\u65b0\u836f\u6570\u76ee\u7684\u5386\u53f2\u7eaa\u5f55\u3002<span style=\"max-width: 100%;line-height: 27px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\uff08\u8be6\u89c1\u4e0b\u65b9\u9605\u8bfb<\/span><span style=\"max-width: 100%;line-height: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u539f\u6587\uff09<\/span><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\"><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">4.&nbsp; <\/span><\/strong><\/strong><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u62dc\u8033\u5b98\u5ba3\uff1a\u7f8eFDA\u6279\u51c6\u9996\u4e2aTRK\u6291\u5236\u5242\u6cbb\u7597NTRK\u57fa\u56e0\u878d\u5408\u665a\u671f\u5b9e\u4f53\u7624<\/span><\/strong><\/strong><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\">11\u670827\u65e5\uff0c\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u7269\u7ba1\u7406\u5c40\uff08FDA\uff09\u6279\u51c6\u9996\u4e2a\u53e3\u670dTRK\u6291\u5236\u5242Larotrectinib\uff08\u5546\u54c1\u540d\u4e3aVitrakvi\u00ae\uff09\uff0c\u7528\u4e8e\u6cbb\u7597\u65e0\u5df2\u77e5\u8010\u836f\u7a81\u53d8\u7684\uff0c\u5e7f\u6cdb\u8f6c\u79fb\u6216\u5c40\u90e8\u624b\u672f\u6cbb\u7597\u6548\u679c\u4e0d\u597d\u7684\uff0c\u73b0\u6709\u6cbb\u7597\u65b9\u6848\u8fdb\u5c55\u6216\u65e0\u53ef\u66ff\u4ee3\u6cbb\u7597\u65b9\u6848\u7684\uff0cNTRK\u57fa\u56e0\u878d\u5408\u7684\u6210\u4eba\u548c\u513f\u7ae5\u5b9e\u4f53\u7624\u60a3\u8005\u3002FDA\u57fa\u4e8e\u8be5\u836f\u7269\u6cbb\u7597\u80bf\u7624\u7684\u603b\u4f53\u7f13\u89e3\u7387\uff08ORR\uff09\u548c\u7f13\u89e3\u6301\u7eed\u65f6\u95f4\uff08DOR\uff09\uff0c\u6309\u7167\u52a0\u901f\u6d41\u7a0b\u6279\u51c6\u4e86\u6b64\u9002\u5e94\u75c7\u3002\u5176\u540e\u7eed\u6279\u51c6\u53ef\u80fd\u53d6\u51b3\u4e8e\u786e\u8bc1\u6027\u8bd5\u9a8c\u4e2d\u5bf9\u4e8e\u4e34\u5e8a\u83b7\u76ca\u7684\u9a8c\u8bc1\u548c\u63cf\u8ff0\u3002<span style=\"max-width: 100%;line-height: 27px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\uff08\u8be6\u89c1\u4e0b\u65b9\u9605\u8bfb<\/span><span style=\"max-width: 100%;line-height: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u539f\u6587\uff09<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\" style=\"margin-top: -4px;max-width: 100%;box-sizing: border-box;width: 556px;text-align: right;overflow-wrap: break-word !important;\">\n<section style=\"margin-left: auto;max-width: 100%;box-sizing: border-box;width: 50px;height: 4px;background-color: rgb(1, 26, 65);overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<section style=\"margin-left: auto;max-width: 100%;box-sizing: border-box;width: 50px;height: 4px;background-color: rgb(1, 26, 65);overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"white-space: normal;max-width: 100%;box-sizing: border-box;line-height: 25.6px;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-top: 3px;padding-bottom: 3px;max-width: 100%;box-sizing: border-box;display: inline-block;border-top: 1px solid rgb(224, 224, 224);border-right-color: rgb(224, 224, 224);border-bottom: 1px solid rgb(224, 224, 224);border-left-color: rgb(224, 224, 224);overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-right: 5px;padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;color: rgb(255, 255, 255);background-color: rgb(1, 26, 65);overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 20px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u7814\u53d1\u8fdb\u5c55<\/strong><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"white-space: normal;max-width: 100%;line-height: 25.6px;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding: 10px;max-width: 100%;box-sizing: border-box;background-color: rgb(239, 239, 239);overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\"><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">1.&nbsp;<\/span><\/strong><\/strong><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">Nature\uff1a\u7518\u9732\u7cd6\u53ef\u6539\u5584\u5316\u7597\u6cbb\u7597\u764c\u75c7\u7684\u6548\u679c<\/span><\/strong><\/strong><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\">\u5728\u4e00\u9879\u65b0\u7684\u7814\u7a76\u4e2d\uff0c\u6765\u81ea\u82f1\u56fd\u6bd4\u7279\u68ee\u764c\u75c7\u7814\u7a76\u6240\u548c\u683c\u62c9\u65af\u54e5\u5927\u5b66\u7684\u7814\u7a76\u4eba\u5458\u53d1\u73b0\u4f5c\u4e3a\u4e00\u79cd\u8425\u517b\u8865\u5145\u5242\uff0c\u7518\u9732\u7cd6\u80fd\u591f\u51cf\u7f13\u80bf\u7624\u751f\u957f\u548c\u589e\u5f3a\u5316\u7597\u5bf9\u591a\u79cd\u764c\u75c7\u5c0f\u9f20\u6a21\u578b\u7684\u7597\u6548\u3002\u8fd9\u4e00\u53d1\u73b0\u6709\u52a9\u4e8e\u4eba\u4eec\u7406\u89e3\u7518\u9732\u7cd6\u5982\u4f55\u53ef\u80fd\u88ab\u7528\u6765\u534f\u52a9\u6cbb\u7597\u764c\u75c7\u3002\u76f8\u5173\u7814\u7a76\u7ed3\u679c\u4e8e2018\u5e7411\u670821\u65e5\u5728\u7ebf\u53d1\u8868\u5728Nature\u671f\u520a\u4e0a\uff0c\u8bba\u6587\u6807\u9898\u4e3a\u201cMannose impairs tumourgrowth and enhances chemotherapy\u201d\u3002<span style=\"max-width: 100%;line-height: 27px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\uff08\u8be6\u89c1\u4e0b\u65b9\u9605\u8bfb<\/span><span style=\"max-width: 100%;line-height: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u539f\u6587\uff09<\/span><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\"><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">2.&nbsp; <\/span><\/strong><\/strong><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u9ed8\u514b\u897f\u59a5\u6614\u5355\u6297\u4e00\u7ebf\u6cbb\u7597\u665a\u671f\u5934\u9888\u764c\u4e2d\u56fdIII\u671f\u4e34\u5e8a\u6210\u529f<\/span><\/strong><\/strong><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\">\u5fb7\u56fd\u5236\u836f\u4e0e\u5316\u5de5\u4f01\u4e1a\u9ed8\u514b\u8fd1\u65e5\u5728\u65b0\u52a0\u5761\u4e3e\u884c\u7684\u6b27\u6d32\u80bf\u7624\u5185\u79d1\u5b66\u4f1a\u4e9a\u6d32\u5927\u4f1a\uff08ESMO ASIA 2018\uff09\u4e0a\u516c\u5e03\u4e86\u9776\u5411\u6297\u764c\u836fErbitux\uff08\u7231\u5fc5\u59a5\uff0ccetuximab\uff0c\u901a\u7528\u540d\uff1a\u897f\u59a5\u6614\u5355\u6297\uff09\u4e0e\u94c2\u7c7b\u5316\u7597\u8054\u5408\u7597\u6cd5\uff08\u79f0\u4e3a\u201cEXTREME\u201d\u65b9\u6848\uff09\u4e00\u7ebf\u6cbb\u7597\u590d\u53d1\u6027\u548c\/\u6216\u8f6c\u79fb\u6027\u5934\u9888\u90e8\u9cde\u72b6\u7ec6\u80de\u764c\uff08R\/M SCCHN\uff09\u4e2d\u56fd\u60a3\u8005\u7684III\u671f\u4e34\u5e8a\u7814\u7a76CHANGE II\u7684\u79ef\u6781\u6570\u636e\u3002<span style=\"max-width: 100%;line-height: 27px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\uff08\u8be6\u89c1\u4e0b\u65b9\u9605\u8bfb<\/span><span style=\"max-width: 100%;line-height: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u539f\u6587\uff09<\/span><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\"><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">3.&nbsp;&nbsp;<\/span><\/strong><\/strong><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u6cbb\u7597\u8840\u6db2\u764c\u75c7\u65b0\u8054\u5408\u7597\u6cd5\u518d\u663e\u4f18\u79c0\u6548\u679c<\/span><\/strong><\/strong><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\">2018\u5e74\u7f8e\u56fd\u8840\u6db2\u5b66\u4f1a\uff08ASH\uff09\u5e74\u4f1a12\u6708\u5373\u5c06\u53ec\u5f00\uff0c\u5e74\u4f1a\u6458\u8981\u8fd1\u65e5\u5728\u7f51\u4e0a\u53d1\u5e03\uff0c\u4e00\u9879\u9488\u5bf9\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u65b0\u7ec4\u5408\u7597\u6cd5\u7684\u4e34\u5e8a\u8fdb\u5c55\u5f15\u8d77\u5173\u6ce8\u3002\u7814\u7a76\u4eba\u5458\u5f00\u5c55\u4e86\u540d\u4e3aMAIA\u76843\u671f\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u8bc4\u4f30DARA\u4e0eRd\u7684\u8054\u5408\u7597\u6cd5\u5728\u4e0d\u9002\u5408\u79fb\u690d\u7684NDMM\u60a3\u8005\u4e2d\u7684\u6548\u679c\uff0c\u6458\u8981\u62a5\u544a\u4e86\u9884\u5148\u8bbe\u5b9a\u7684\u4e2d\u671f\u6570\u636e\u5206\u6790\u3002\u7ed3\u679c\u663e\u793a\uff0c\u5bf9\u4e8e\u4e0d\u9002\u5408\u79fb\u690d\u7597\u6cd5\u7684NDMM\u60a3\u8005\uff0c\u4e0e\u5355\u7528Rd\u7597\u6cd5\u76f8\u6bd4\uff0cDARA\u8054\u5408\u7597\u6cd5\u53ef\u964d\u4f4e45%\u7684\u75be\u75c5\u8fdb\u5c55\u548c\u6b7b\u4ea1\u98ce\u9669\uff0c\u4e14\u5b89\u5168\u6027\u4e0e\u8fc7\u53bbDARA\u7684\u7814\u7a76\u4e00\u81f4\u3002<span style=\"max-width: 100%;line-height: 27px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\uff08\u8be6\u89c1\u4e0b\u65b9\u9605\u8bfb<\/span><span style=\"max-width: 100%;line-height: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u539f\u6587\uff09<\/span><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\"><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">4.&nbsp;&nbsp;<\/span><\/strong><\/strong><strong style=\"max-width: 100%;line-height: 27px;color: rgb(1, 26, 65);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;text-indent: 0cm;line-height: 20pt;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u65b0\u7814\u7a76\u9274\u5b9a\u51fa\u6c49\u5766\u75c5\u6bd2\u5165\u4fb5\u5bbf\u4e3b\u7ec6\u80de\u6240\u9700\u53d7\u4f53<\/span><\/strong><\/strong><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\">\u6c49\u5766\u75c5\u6bd2\uff08hantavirus\uff09\u5f15\u8d77\u4e25\u91cd\u7684\u6709\u65f6\u662f\u81f4\u547d\u6027\u7684\u547c\u5438\u9053\u611f\u67d3\uff0c\u4f46\u662f\u5b83\u4eec\u5982\u4f55\u611f\u67d3\u80ba\u7ec6\u80de\u4e00\u76f4\u662f\u4e2a\u8c1c\u3002\u5728\u4e00\u9879\u65b0\u7684\u7814\u7a76\u4e2d\uff0c\u6765\u81ea\u7f8e\u56fd\u3001\u8377\u5170\u3001\u5fb7\u56fd\u3001\u52a0\u62ff\u5927\u3001\u6cd5\u56fd\u3001\u667a\u5229\u548c\u5965\u5730\u5229\u7684\u7814\u7a76\u4eba\u5458\u62a5\u9053\u6c49\u5766\u75c5\u6bd2\u901a\u8fc7\u8ba9\u4e00\u79cd\u79f0\u4e3a\u539f\u9499\u9ecf\u86cb\u767d-1\uff08protocadherin-1, PCDH1\uff09\u7684\u7ec6\u80de\u8868\u9762\u53d7\u4f53\u66b4\u9732\u51fa\u6765\u800c\u4fb5\u5165\u80ba\u7ec6\u80de\u4e2d\u3002\u5254\u9664\u80ba\u7ec6\u80de\u4e0a\u7684\u8fd9\u79cd\u53d7\u4f53\u8ba9\u5b9e\u9a8c\u52a8\u7269\u9ad8\u5ea6\u62b5\u6297\u6c49\u5766\u75c5\u6bd2\u611f\u67d3\u3002\u8fd9\u4e9b\u53d1\u73b0\u8868\u660e\u9776\u5411PCDH1\u53ef\u80fd\u662f\u62b5\u6297\u4e00\u79cd\u62b5\u6297\u81f4\u547d\u6027\u7684\u6c49\u5766\u75c5\u6bd2\u80ba\u7efc\u5408\u5f81\uff08hantaviruspulmonary syndrome, HPS\uff09\u7684\u6709\u7528\u7b56\u7565\u3002<span style=\"max-width: 100%;line-height: 27px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\uff08\u8be6\u89c1\u4e0b\u65b9\u9605\u8bfb<\/span><span style=\"max-width: 100%;line-height: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u539f\u6587\uff09<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\" style=\"margin-top: -4px;max-width: 100%;box-sizing: border-box;width: 556px;text-align: right;overflow-wrap: break-word !important;\">\n<section style=\"margin-left: auto;max-width: 100%;box-sizing: border-box;width: 50px;height: 4px;background-color: rgb(1, 26, 65);overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<section style=\"margin-left: auto;max-width: 100%;box-sizing: border-box;width: 50px;height: 4px;background-color: rgb(1, 26, 65);overflow-wrap: break-word !important;\"><br  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-bottom: 20px;white-space: normal;max-width: 100%;min-height: 1em;line-height: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(136, 136, 136);font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u6765\u6e90\uff1a<\/strong><\/span><strong style=\"color: rgb(136, 136, 136);font-size: 14px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u56fd\u5bb6\u536b\u5065\u59d4\u3001\u4e2d\u56fd\u533b\u836f\u62a5\u3001\u836f\u5e97\u7ecf\u7406\u4eba\u3001\u65b0\u6d6a\u533b\u836f\u65b0\u95fb\u3001\u8d5b\u67cf\u84dd\u3001\u52a8\u8109\u7f51\u3001\u521b\u9274\u6c47\u3001\u3001\u751f\u7269\u8c37<\/strong><\/p>\n<p style=\"white-space: normal;text-align: center;\"><img class=\"\"       style=\"color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;letter-spacing: 0.544px;font-size: 17px;box-sizing: border-box !important;word-wrap: break-word !important;width: 677px !important;visibility: visible 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