{"id":64858,"date":"2018-11-22T01:00:00","date_gmt":"2018-12-07T03:43:29","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/12\/07\/a0c19b4933\/"},"modified":"2018-12-07T11:43:30","modified_gmt":"2018-12-07T03:43:30","slug":"a0c19b4933","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/64858\/","title":{"rendered":"\u764c\u7ec6\u80de\u751f\u957f\u65b0\u673a\u5236\u88ab\u53d1\u73b0"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<section  class=\"_135editor\" style=\"font-size: 16px;white-space: normal;font-family: \u5fae\u8f6f\u96c5\u9ed1;border-color: currentcolor;border-style: none;border-width: 0px;box-sizing: border-box;\">\n<section class=\"_135editor\"     style=\"border-color: currentcolor;border-style: none;border-width: 0px;box-sizing: border-box;\">\n<section class=\"135brush\"  placeholder=\"\u6df1\u8272\u8fb9\u6846\u6807\u9898\" style=\"margin-top: 10px;margin-bottom: 10px;padding: 10px;line-height: 25px;color: rgb(109, 4, 14);border-top-left-radius: 4px;border-top-right-radius: 4px;border-bottom-right-radius: 4px;border-bottom-left-radius: 4px;box-shadow: rgb(153, 153, 153) 2px 2px 4px 0px;border-left-width: 10px;border-left-style: solid;border-color: rgb(21, 59, 143);background-color: rgb(225, 227, 226);box-sizing: border-box;\">\n<p style=\"margin-top: 5px;margin-bottom: 5px;padding-right: 10px;padding-left: 10px;text-align: justify;font-size: 14px;line-height: 2em;\"><span style=\"text-align: justify;color: rgb(0, 0, 0);text-indent: 0em;font-size: 15px;\"><span style=\"font-size: 15px;\"><span style=\"font-size: 15px;\">\u5728\u4e00\u9879\u65b0\u7684\u7814\u7a76\u4e2d\uff0c\u6765\u81ea\u7f8e\u56fd\u52a0\u5dde\u5927\u5b66\u6d1b\u6749\u77f6\u5206\u6821\u7684\u7814\u7a76\u4eba\u5458\u9274\u5b9a\u51fa\u80ba\u764c\u7ec6\u80de\u80fd\u591f\u5229\u7528\u4e00\u79cd\u79f0\u4e3aSGLT2\uff08\u94a0\u8461\u8404\u7cd6\u8f6c\u8fd0\u86cb\u767d2\uff09\u7684\u86cb\u767d\u83b7\u5f97\u8461\u8404\u7cd6\u3002<\/span><\/span><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  class=\"_135editor\" style=\"font-size: 16px;white-space: normal;font-family: \u5fae\u8f6f\u96c5\u9ed1;border-color: currentcolor;border-style: none;border-width: 0px;box-sizing: border-box;\">\n<section  style=\"padding-right: 5px;display: inline-block;width: 558px;border-width: 0px 10px 1px 0px;border-style: solid;border-bottom-color: rgb(27, 58, 149);border-left-color: rgb(27, 58, 149);border-right-color: rgb(27, 58, 149);border-bottom-left-radius: 0px;border-top-right-radius: 0px;box-sizing: border-box;\">\n<section style=\"text-align: right;transform: translate3d(0px, 0px, 0px);\">\n<p class=\"135brush\" >&nbsp;\u5168\u6587671\u5b57\uff0c\u7528\u65f61\u5206\u949f<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"_135editor\"   style=\"border-color: currentcolor;border-style: none;border-width: 0px;box-sizing: border-box;\">\n<section class=\"135brush\" >\n<p style=\"white-space: normal;text-align: justify;font-size: 14px;line-height: 2em;padding-right: 10px;padding-left: 10px;margin: 20px 0%;\"><span style=\"font-size: 15px;\">\u5728\u4e00\u9879\u65b0\u7684\u7814\u7a76\u4e2d\uff0c\u6765\u81ea\u7f8e\u56fd\u52a0\u5dde\u5927\u5b66\u6d1b\u6749\u77f6\u5206\u6821\u7684\u7814\u7a76\u4eba\u5458\u9274\u5b9a\u51fa\u80ba\u764c\u7ec6\u80de\u80fd\u591f\u5229\u7528\u4e00\u79cd\u79f0\u4e3aSGLT2\uff08sodium glucose transporter 2\uff0c \u94a0\u8461\u8404\u7cd6\u8f6c\u8fd0\u86cb\u767d2\uff09\u7684\u86cb\u767d\u83b7\u5f97\u8461\u8404\u7cd6\u3002\u8fd9\u4e00\u53d1\u73b0\u63d0\u4f9b\u8bc1\u636e\u8868\u660eSGLT2\u53ef\u80fd\u662f\u4e00\u79cd\u65b0\u578b\u751f\u7269\u6807\u5fd7\u7269\uff0c\u79d1\u5b66\u5bb6\u4eec\u53ef\u80fd\u5229\u7528\u5b83\u534f\u52a9\u8bca\u65ad\u80ba\u90e8\u764c\u524d\u75c5\u53d8\u548c\u65e9\u671f\u80ba\u764c\u3002\u76f8\u5173\u7814\u7a76\u7ed3\u679c\u53d1\u8868\u57282018\u5e7411\u670814\u65e5\u7684Science Translational Medicine\u671f\u520a\u4e0a\uff0c\u8bba\u6587\u6807\u9898\u4e3a\u201cSodium-glucose transporter 2 is a diagnostic and therapeutic target for early-stage lung adenocarcinoma\u201d\u3002<\/span><\/p>\n<p style=\"white-space: normal;text-align: justify;font-size: 14px;line-height: 2em;padding-right: 10px;padding-left: 10px;margin: 20px 0%;\"><span style=\"font-size: 15px;\">\u764c\u7ec6\u80de\u9700\u8981\u5927\u91cf\u7684\u8461\u8404\u7cd6\u624d\u80fd\u5b58\u6d3b\u548c\u751f\u957f\u3002\u8fc7\u53bb\u7684\u7814\u7a76\u5df2\u786e\u5b9a\u86cb\u767dGLUT\uff08glucose transporter\uff0c \u8461\u8404\u7cd6\u8f6c\u8fd0\u86cb\u767d\uff09\u662f\u8eab\u4f53\u7528\u6765\u5411\u80bf\u7624\u8fd0\u9001\u8461\u8404\u7cd6\u7684\u4e3b\u8981\u624b\u6bb5\u3002\u7136\u800c\uff0c\u8fd1\u671f\u7684\u66f4\u591a\u7814\u7a76\u5df2\u53d1\u73b0\u4e00\u4e9b\u764c\u75c7\uff0c\u6bd4\u5982\u524d\u5217\u817a\u764c\u548c\u80f0\u817a\u764c\uff0c\u4e5f\u4f9d\u8d56\u4e8eSGLT2\u6765\u5229\u7528\u8461\u8404\u7cd6\uff0c\u8fd9\u5c31\u4fc3\u4f7f\u4e86\u8fd9\u4e9b\u6765\u81ea\u52a0\u5dde\u5927\u5b66\u6d1b\u6749\u77f6\u5206\u6821\u7684\u7814\u7a76\u4eba\u5458\u7814\u7a76SGLT2\u5728\u80ba\u764c\u4e2d\u7684\u4f5c\u7528\u3002<\/span><\/p>\n<p style=\"white-space: normal;text-align: justify;font-size: 14px;line-height: 2em;padding-right: 10px;padding-left: 10px;margin: 20px 0%;\"><span style=\"font-size: 15px;\">\u5728\u66f4\u5bb9\u6613\u6cbb\u7597\u7684\u65f6\u5019\u53d1\u73b0\u66f4\u65e9\u5730\u8bca\u65ad\u80ba\u764c\u7684\u65b9\u6cd5\u662f\u6709\u5fc5\u8981\u7684\uff0c\u8fd9\u662f\u56e0\u4e3a\u5b83\u76ee\u524d\u662f\u5168\u7403\u7537\u6027\u548c\u5973\u6027\u764c\u75c7\u76f8\u5173\u6b7b\u4ea1\u7684\u4e3b\u8981\u539f\u56e0\u3002<\/span><\/p>\n<p style=\"white-space: normal;text-align: justify;font-size: 14px;line-height: 2em;padding-right: 10px;padding-left: 10px;margin: 20px 0%;\"><span style=\"font-size: 15px;\">\u8fd9\u4e9b\u7814\u7a76\u4eba\u5458\u4f7f\u7528\u6b63\u7535\u5b50\u53d1\u5c04\u65ad\u5c42\u626b\u63cf\uff08PET\uff09\u6765\u6355\u83b7\u80ba\u764c\u7ec6\u80de\u4e2d\u7684SGLT\u6d3b\u6027\u3002\u4ed6\u4eec\u80fd\u591f\u5229\u7528SGLT2\u6d3b\u6027\u6765\u76d1\u6d4bSGLT2\u6291\u5236\u5242\u5bf9\u9057\u4f20\u6027\u80ba\u764c\u5c0f\u9f20\u6a21\u578b\u548c\u5df2\u690d\u5165\u4eba\u80ba\u80bf\u7624\u7684\u5c0f\u9f20\u7684\u7597\u6548\u3002<\/span><\/p>\n<p style=\"white-space: normal;text-align: justify;font-size: 14px;line-height: 2em;padding-right: 10px;padding-left: 10px;margin: 20px 0%;\"><span style=\"font-size: 15px;\">\u8fd9\u4e9b\u7814\u7a76\u4eba\u5458\u5728\u4eba\u7c7b\u80ba\u764c\u6807\u672c\u4e2d\u53d1\u73b0\u5f02\u5e38\u9ad8\u6c34\u5e73\u7684SGLT2\uff0c\u8fd9\u5c31\u8868\u660e\u8fd9\u4e9b\u80ba\u80bf\u7624\u5728\u65e9\u671f\u7684\u751f\u957f\u9636\u6bb5\uff0c\u751a\u81f3\u5728\u80ba\u764c\u4ea7\u751f\u4e4b\u524d\u7684\u764c\u524d\u75c5\u53d8\u65f6\uff0c\u4e3b\u8981\u5229\u7528SGLT2\u800c\u4e0d\u662fGLUT\u6765\u8f6c\u8fd0\u8461\u8404\u7cd6\u3002<\/span><\/p>\n<p style=\"white-space: normal;text-align: justify;font-size: 14px;line-height: 2em;padding-right: 10px;padding-left: 10px;margin: 20px 0%;\"><span style=\"font-size: 15px;\">\u8fd9\u9879\u7814\u7a76\u8868\u660e\u5728\u66f4\u5bb9\u6613\u6cbb\u7597\u7684\u65f6\u5019\uff0c\u4eba\u4eec\u53ef\u80fd\u80fd\u591f\u66f4\u65e9\u5730\u68c0\u6d4b\u80ba\u764c\u3002\u901a\u8fc7\u4f7f\u7528SGLT2\u4f5c\u4e3a\u4e00\u79cd\u751f\u7269\u6807\u5fd7\u7269\uff0c\u4e0d\u4ec5\u53ef\u80fd\u6bd4\u5f53\u524d\u66f4\u65e9\u5730\u53d1\u73b0\u80ba\u764c\uff0c\u800c\u4e14\u751a\u81f3\u53ef\u80fd\u5728\u764c\u524d\u75c5\u53d8\u53d1\u751f\u764c\u53d8\u4e4b\u524d\u53d1\u73b0\u5b83\u3002\u8fd9\u4e9b\u7814\u7a76\u4eba\u5458\u8fd8\u63d0\u4f9b\u4e86\u8bc1\u636e\u8868\u660e\u4f5c\u4e3a\u7f8e\u56fdFDA\u6279\u51c6\u7684\u4e00\u7c7b\u5e38\u7528\u7684SGLT2\u6291\u5236\u5242\u836f\u7269\uff0c\u5217\u51c0\u7c7b\u836f\u7269\uff08\u76ee\u524d\u7528\u4e8e\u6cbb\u7597\u7cd6\u5c3f\u75c5\uff09\u53ef\u80fd\u6709\u52a9\u4e8e\u963b\u65ad\u764c\u7ec6\u80de\u4e2d\u7684SGLT2\u6d3b\u6027\u3002\u5217\u51c0\u7c7b\u836f\u7269\u53ef\u80fd\u7528\u4e8e\u963b\u65ad\u8461\u8404\u7cd6\u6444\u53d6\u5e76\u6709\u52a9\u4e8e\u51cf\u5c11\u80bf\u7624\u751f\u957f\u3002<\/span><\/p>\n<p style=\"margin-top: 20px;margin-bottom: 20px;padding-right: 10px;padding-left: 10px;white-space: normal;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &#39;Helvetica Neue&#39;, &#39;PingFang SC&#39;, &#39;Hiragino Sans GB&#39;, &#39;Microsoft YaHei UI&#39;, &#39;Microsoft YaHei&#39;, Arial, sans-serif;letter-spacing: 0.5440000295639038px;text-align: justify;font-size: 14px;line-height: 2em;max-width: 100% !important;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"font-size: 15px;font-family: \u5fae\u8f6f\u96c5\u9ed1;color: rgb(136, 136, 136);letter-spacing: 1px;max-width: 100% !important;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\u6765\u6e90<\/strong><strong style=\"font-size: 15px;font-family: \u5fae\u8f6f\u96c5\u9ed1;color: rgb(136, 136, 136);letter-spacing: 1px;max-width: 100% !important;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\uff1a\u533b\u836f\u7f51<\/strong><\/p>\n<p style=\"white-space: normal;text-align: justify;font-size: 14px;line-height: 2em;padding-right: 10px;padding-left: 10px;margin: 20px 0%;\"><span style=\"font-size: 15px;max-width: 100% !important;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"      style=\"font-size: 17px;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible !important;width: 677px !important;height: auto !important;\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/9-1544154210.jpeg\" alt=\"\u764c\u7ec6\u80de\u751f\u957f\u65b0\u673a\u5236\u88ab\u53d1\u73b0\" title=\"\u764c\u7ec6\u80de\u751f\u957f\u65b0\u673a\u5236\u88ab\u53d1\u73b0\"  \/><\/span><span style=\"font-size: 15px;\"><\/span><br  \/><\/p>\n<\/section>\n<\/section><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u5728\u4e00\u9879\u65b0\u7684\u7814\u7a76\u4e2d\uff0c\u6765\u81ea\u7f8e\u56fd\u52a0\u5dde\u5927\u5b66\u6d1b\u6749\u77f6\u5206\u6821\u7684\u7814\u7a76\u4eba\u5458\u9274\u5b9a\u51fa\u80ba\u764c\u7ec6\u80de\u80fd\u591f\u5229\u7528\u4e00\u79cd\u79f0\u4e3aSGLT2\uff08\u94a0\u8461\u8404\u7cd6\u8f6c\u8fd0\u86cb [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":64859,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/64858"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=64858"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/64858\/revisions"}],"predecessor-version":[{"id":64861,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/64858\/revisions\/64861"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/64859"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=64858"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=64858"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=64858"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}