{"id":65539,"date":"2018-11-02T01:00:00","date_gmt":"2018-12-07T03:51:25","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/12\/07\/9de4426655\/"},"modified":"2018-12-07T11:51:27","modified_gmt":"2018-12-07T03:51:27","slug":"9de4426655","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/65539\/","title":{"rendered":"\u80ba\u764c\u5e02\u573a\u89d2\u9010\u5347\u7ea7\uff01\u9ed8\u514b\u62a2\u5360\u4f18\u52bf\uff01"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<section  class=\"\" style=\"font-size: 16px;white-space: normal;color: rgb(51, 51, 51);letter-spacing: 0.5440000295639038px;text-align: justify;font-family: \u5fae\u8f6f\u96c5\u9ed1;border: 0px none;max-width: 100% !important;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\"     style=\"border: 0px none;max-width: 100% !important;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\"  placeholder=\"\u6df1\u8272\u8fb9\u6846\u6807\u9898\" style=\"margin-top: 10px;margin-bottom: 10px;padding: 10px;line-height: 25px;color: rgb(109, 4, 14);border-top-left-radius: 4px;border-top-right-radius: 4px;border-bottom-right-radius: 4px;border-bottom-left-radius: 4px;box-shadow: rgb(153, 153, 153) 2px 2px 4px 0px;border-left-width: 10px;border-left-style: solid;border-color: rgb(21, 59, 143);background-color: rgb(225, 227, 226);max-width: 100% !important;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"margin-top: 5px;margin-bottom: 5px;padding-right: 10px;padding-left: 10px;min-height: 1em;font-size: 14px;line-height: 2em;max-width: 100% !important;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"color: rgb(0, 0, 0);text-indent: 0em;font-size: 15px;max-width: 100% !important;box-sizing: border-box !important;word-wrap: break-word !important;text-align: justify;\">\u672c\u5468\u4e8c\uff0cFDA\u6279\u51c6\u4e86\u9ed8\u514b\u516c\u53f8\u7684PD-1\u6297\u4f53Keytruda\u8054\u5408\u5316\u7597\uff0c\u7528\u4e8e\u4ee5\u524d\u672a\u7ecf\u6cbb\u7597\u7684\u9cde\u72b6\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u60a3\u8005\uff0c\u800c\u4e0d\u7ba1\u5176\u9776\u5411\u751f\u7269\u6807\u5fd7\u7269PD-L1\u7684\u6c34\u5e73\u3002\u8fd9\u662fPD-1\/PD-L1\u7c7b\u6297\u764c\u836f\u7269\u4e2d\u7b2c\u4e00\u4e2a\u83b7\u6b64\u6b8a\u8363\u7684\u4ea7\u54c1\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  class=\"\" style=\"font-size: 16px;white-space: normal;color: rgb(51, 51, 51);letter-spacing: 0.5440000295639038px;text-align: justify;font-family: \u5fae\u8f6f\u96c5\u9ed1;border: 0px none;max-width: 100% !important;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section  style=\"padding-right: 5px;display: inline-block;width: 558px;border-width: 0px 10px 1px 0px;border-style: solid;border-bottom-color: 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15px;\">\u867d\u7136\u8fd9\u9879\u7814\u7a76\u7684\u6210\u5c31\u593a\u76ee\uff0c\u4f46Keytruda\u4e0d\u662f\u552f\u4e00\u4e00\u4e2a\u62e5\u6709\u79ef\u6781\u6570\u636e\u7684\u3002\u540c\u6837\u5728ASCO\u5e74\u4f1a\u4e0a\uff0c\u7f57\u6c0f\u516c\u5e03\u58f0\u660e\uff0catezolizumab\uff08\u5546\u54c1\u540d\uff1aTecentriq\uff09\u8054\u5408\u5316\u7597\u53ef\u4ee5\u5c06\u75be\u75c5\u6076\u5316\u6216\u6b7b\u4ea1\u7684\u98ce\u9669\u964d\u4f4e29%\u3002<\/span><\/p>\n<p style=\"white-space: normal;text-align: justify;font-size: 14px;line-height: 2;padding-right: 10px;padding-left: 10px;margin: 15px 0%;\"><span style=\"font-size: 15px;\">\u5bf9\u6bd4\u4e4b\u4e0b\uff0cKeytruda\u5f3a\u5927\u7684\u751f\u5b58\u6570\u636e\u6216\u6210\u4e3a\u9ed8\u514b\u5728\u80ba\u764c\u9886\u57df\u8d76\u8d85\u7f57\u6c0f\u7684\u5f3a\u52a9\u653b\u3002<\/span><\/p>\n<p style=\"white-space: normal;text-align: justify;font-size: 14px;line-height: 2;padding-right: 10px;padding-left: 10px;margin: 15px 0%;\"><span style=\"font-size: 15px;\">\u6839\u636e\u4e2d\u56fd\u533b\u836f\u5de5\u4e1a\u4fe1\u606f\u4e2d\u5fc3PDB\u5168\u7403\u7545\u9500\u836f500\u5f3a\u7684\u7edf\u8ba1\u6570\u636e\uff0c2017\u5e74Keytruda\u7684\u5168\u7403\u9500\u552e\u91d1\u989d\u4e3a38.09\u4ebf\u7f8e\u5143\uff0c\u6bd4\u53bb\u5e74\u589e\u957f171.7%\u3002\u800c\u9ed8\u514b\u8fd1\u65e5\u4e5f\u5ba3\u5e03\uff0c2018\u5e74\u7b2c\u4e09\u5b63\u5ea6\u533b\u836f\u677f\u5757\u7684\u9500\u552e\u989d\u4e3a97\u4ebf\u7f8e\u5143\u3002\u8fd9\u4efd\u4e1a\u7ee9\u7684\u83b7\u5f97\u4e3b\u8981\u662f\u7531\u80bf\u7624\u4e1a\u52a1\u65b9\u9762\u4ee5\u53caKeytruda\u9500\u91cf\u7684\u5f3a\u52b2\u589e\u957f\u63a8\u52a8\u7684\uff0c\u5e76\u4e14\u4e0e\u8be5\u4ea7\u54c1\u65b0\u9002\u5e94\u75c7\u7684\u6279\u51c6\u4ee5\u53ca\u5176\u4f5c\u4e3a\u552f\u4e00\u4e00\u7ebfPD-1\u5355\u6297\u6cbb\u7597\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7684\u5730\u4f4d\u5bc6\u5207\u76f8\u5173\u3002\u5f53\u5b63\uff0cKeytruda\u9500\u552e\u989d\u8fbe\u523019\u4ebf\u7f8e\u5143\uff0c\u8f832017\u5e74\u7b2c\u4e09\u5b63\u5ea6\u589e\u957f80%\uff0c\u8f832018\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u589e\u957f14%\u3002<\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/3-1544154686.jpeg\" alt=\"\u80ba\u764c\u5e02\u573a\u89d2\u9010\u5347\u7ea7\uff01\u9ed8\u514b\u62a2\u5360\u4f18\u52bf\uff01\" title=\"\u80ba\u764c\u5e02\u573a\u89d2\u9010\u5347\u7ea7\uff01\u9ed8\u514b\u62a2\u5360\u4f18\u52bf\uff01\"  \/><\/p>\n<p style=\"white-space: normal;text-align: center;font-size: 14px;line-height: normal;padding-right: 10px;padding-left: 10px;margin: 5px 0px;\"><span style=\"font-size: 15px;\"><\/span><span style=\"font-size: 12px;\"><em>\u6570\u636e\u6765\u6e90\uff1a\u4e2d\u56fd\u533b\u836f\u5de5\u4e1a\u4fe1\u606f\u4e2d\u5fc3PDB\u6570\u636e\u5e93<\/em><\/span><\/p>\n<p style=\"white-space: normal;text-align: justify;font-size: 14px;line-height: 2;padding-right: 10px;padding-left: 10px;margin: 15px 0%;\"><span style=\"font-size: 15px;\">Tecentriq\u57282017\u5e74\u8868\u73b0\u51fa\u4e86\u5f3a\u52b2\u7684\u589e\u957f\u529b\u3002\u4e2d\u56fd\u533b\u836f\u5de5\u4e1a\u4fe1\u606f\u4e2d\u5fc3PDB\u5168\u7403\u7545\u9500\u836f500\u5f3a\u7684\u6570\u636e\u663e\u793a\uff0c2017\u5e74Tecentriq\u7684\u9500\u552e\u989d\u8fbe\u52305.95\u4ebf\u7f8e\u5143\uff0c\u589e\u957f\u7387\u4e3a212.2%\uff0c\u5927\u6709\u540e\u6765\u8005\u594b\u529b\u76f4\u8ffd\u4e4b\u52bf\u3002<\/span><\/p>\n<p style=\"text-align: center;margin-top: 5px;margin-bottom: 5px;line-height: normal;\"><img class=\"\"       style=\"width: 502px;height: 306px;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/0-1544154686.jpg\" alt=\"\u80ba\u764c\u5e02\u573a\u89d2\u9010\u5347\u7ea7\uff01\u9ed8\u514b\u62a2\u5360\u4f18\u52bf\uff01\" title=\"\u80ba\u764c\u5e02\u573a\u89d2\u9010\u5347\u7ea7\uff01\u9ed8\u514b\u62a2\u5360\u4f18\u52bf\uff01\"  \/><\/p>\n<p style=\"text-align: center;\"><em style=\"font-size: 12px;\"><span style=\"text-align: justify;\">\u6570\u636e\u6765\u6e90\uff1a\u4e2d\u56fd\u533b\u836f\u5de5\u4e1a\u4fe1\u606f\u4e2d\u5fc3PDB\u6570\u636e\u5e93<\/span><\/em><br  \/><\/p>\n<p style=\"white-space: normal;text-align: left;font-size: 14px;line-height: normal;padding-right: 10px;padding-left: 10px;margin: 5px 0%;\"><em><span style=\"font-size: 15px;\"><span style=\"font-size: 14px;text-align: justify;\"><br  \/><\/span><\/span><\/em><\/p>\n<section  class=\"_135editor\" style=\"white-space: normal;border: 0px none;box-sizing: border-box;\">\n<p style=\"margin-top: 8px;line-height: 28px;min-height: 32px;border-bottom-width: 2px;border-bottom-style: solid;text-align: justify;border-bottom-color: #003472;color: #003472;\"><strong>\u80ba\u764c\u5e02\u573a\u7fa4\u96c4\u4e89\u9738\u6982\u51b5<\/strong><\/p>\n<\/section>\n<p style=\"white-space: normal;text-align: justify;font-size: 14px;line-height: 2;padding-right: 10px;padding-left: 10px;margin: 15px 0%;\"><span style=\"font-size: 15px;\">\u4e1a\u5185\u8ba4\u4e3a\uff0c\u8fd9\u9879\u6700\u65b0\u7684\u7814\u7a76\u8fdb\u5c55\u5de9\u56fa\u4e86Keytruda\u5728\u80ba\u764c\u5e02\u573a\u7684\u4e3b\u5bfc\u5730\u4f4d\u3002\u4f5c\u4e3a\u6570\u5341\u5e74\u4e00\u89c1\u7684\u660e\u661f\u7ea7\u836f\u7269\uff0cKeytruda\u5728NSCLC\u7684\u6cbb\u7597\u4e0a\u83b7\u5f97\u4e86FDA\u4e24\u6b21\u70b9\u5934\uff0c\u7ed9\u5176\u4ed6\u540c\u7ea7\u5bf9\u624b\u5e26\u6765\u4e86\u538b\u8feb\u548c\u6050\u614c\u611f\u3002\u9664\u4e86\u7f57\u6c0f\u7684Tecentriq\uff0c\u4ed6\u4eec\u8fd8\u5305\u62ecBMS\u7684PD-1\u6297\u4f53nivolumab\uff08\u5546\u54c1\u540d\uff1aOpdivo\uff09\u3001\u963f\u65af\u5229\u5eb7\u7684durvalumab\uff08\u5546\u54c1\u540d\uff1aImfinzi\uff09\u4ee5\u53ca\u8f89\u745e\u548c\u5fb7\u56fd\u9ed8\u514b\u516c\u53f8\u7684avelumab\uff08\u5546\u54c1\u540d\uff1aBavencio\uff09\u3002<\/span><br  \/><\/p>\n<p style=\"white-space: normal;text-align: justify;font-size: 14px;line-height: 2;padding-right: 10px;padding-left: 10px;margin: 15px 0%;\"><strong>Opdivo<\/strong><\/p>\n<p style=\"text-align: center;\"><img class=\"\"       style=\"width: 523px;height: 319px;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/1-1544154686.jpg\" alt=\"\u80ba\u764c\u5e02\u573a\u89d2\u9010\u5347\u7ea7\uff01\u9ed8\u514b\u62a2\u5360\u4f18\u52bf\uff01\" title=\"\u80ba\u764c\u5e02\u573a\u89d2\u9010\u5347\u7ea7\uff01\u9ed8\u514b\u62a2\u5360\u4f18\u52bf\uff01\"  \/><\/p>\n<p style=\"text-align: center;\"><em style=\"font-size: 12px;\"><span style=\"text-align: justify;\">\u6570\u636e\u6765\u6e90\uff1a\u4e2d\u56fd\u533b\u836f\u5de5\u4e1a\u4fe1\u606f\u4e2d\u5fc3PDB\u6570\u636e\u5e93<\/span><\/em><br  \/><\/p>\n<p style=\"white-space: normal;text-align: justify;font-size: 14px;line-height: 2;padding-right: 10px;padding-left: 10px;margin: 15px 0%;\"><strong>Imfinzi<\/strong><\/p>\n<p style=\"white-space: normal;text-align: justify;font-size: 14px;line-height: 2;padding-right: 10px;padding-left: 10px;margin: 15px 0%;\"><span style=\"font-size: 15px;\">\u4eca\u5e74\u4e8c\u6708\uff0cFDA\u6279\u51c6\u4e86\u963f\u65af\u5229\u5eb7\u7684Imfinzi \u7528\u4e8e\u6cbb\u7597\u65e0\u6cd5\u624b\u672f\u3001\u5316\u7597\u6216\u653e\u7597\u540e\u75c5\u60c5\u7a33\u5b9a\u7684\u4e09\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff0c\u4f7f\u5176\u6210\u4e3a\u7b2c\u4e00\u4e2a\u4e0a\u5e02\u7684\u4e09\u671f\u80ba\u764c\u5316\u653e\u7597\u540e\u7ef4\u6301\u7597\u6cd5\uff0c\u4e5f\u662f\u7b2c\u4e94\u4e2a\u4e0a\u5e02\u7684PD-1\/PD-L1\u836f\u7269\u3002\u7531\u4e8e2018\u5e74\u624d\u4e0a\u5e02\uff0c\u76ee\u524d\u6682\u65e0\u9500\u552e\u6570\u636e\u3002<\/span><\/p>\n<p style=\"white-space: normal;text-align: justify;font-size: 14px;line-height: 2;padding-right: 10px;padding-left: 10px;margin: 15px 0%;\"><strong>Bavencio<\/strong><\/p>\n<p style=\"white-space: normal;text-align: justify;font-size: 14px;line-height: 2;padding-right: 10px;padding-left: 10px;margin: 15px 0%;\"><span style=\"font-size: 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