{"id":67690,"date":"2018-10-16T01:00:00","date_gmt":"2018-12-07T04:17:14","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/12\/07\/b7f75e1d57\/"},"modified":"2018-12-07T12:17:22","modified_gmt":"2018-12-07T04:17:22","slug":"b7f75e1d57","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/67690\/","title":{"rendered":"\u6536\u85cf|\u6211\u4eec\u4e3a\u60a8\u89c4\u5212\u4e86\u4e09\u5929\u6700\u6709\u4ef7\u503c\u7684\u521b\u65b0\u836f\u5927\u4f1a \uff08DDI\uff09"},"content":{"rendered":"
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\u8f6c\u8f7d\u6765\u6e90\uff1aDIA\u8ba2\u9605\u53f7<\/span><\/p>\n

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\"\u6536\u85cf|\u6211\u4eec\u4e3a\u60a8\u89c4\u5212\u4e86\u4e09\u5929\u6700\u6709\u4ef7\u503c\u7684\u521b\u65b0\u836f\u5927\u4f1a<\/section>\n<\/section>\n<\/section>\n
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\u4f1a\u8bae<\/p>\n

\u6d41\u7a0b<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u661f\u671f\u4e09 | 2018 \u5e7410\u670824\u65e5 | \u5927\u4f1a\u65e5\u7a0b \u7b2c\u4e00\u5929<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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07:30-17:00<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u4f1a\u8bae\u6ce8\u518c<\/p>\n

\u6ce8\u518c\u53f0, \u4e00\u5c42\u5927\u5802
<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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09:00-12:00<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u4f1a\u524d\u7814\u8ba8\u4f1a<\/p>\n

\u80bf\u7624\u514d\u75ab\u4e2d\u7684\u4eba\u6e90\u5316\u52a8\u7269\u6478\u578b<\/p>\n

\u5bb4\u4f1a\u5385 1, \u4e09\u5c42<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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12:00-13:30<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u5348\u4f11<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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13:30-15:25<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u5f00\u5e55\u5f0f\u5168\u4f53\u5927\u4f1a<\/p>\n

\u5bb4\u4f1a\u5385 1&2, \u4e09\u5c42<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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15:25-15:55<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u8336\u6b47<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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15:55-16:50<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u7279\u522b\u8bba\u575b<\/p>\n

\u5bb4\u4f1a\u53851 & 2, \u4e09\u5c42<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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17:00-18:00<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u6b22\u8fce\u4ea4\u6d41\u4f1a<\/p>\n

\u864e\u4e18\u5385, \u4e00\u5c42<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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18:00-19:30<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u8bb2\u8005\/\u5609\u5bbe\u665a\u5bb4 \uff08\u4ec5\u9650\u9080\u8bf7\uff09<\/p>\n

\u5bb4\u4f1a\u53851 & 2 , \u4e09\u5c42<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u661f\u671f\u56db | 2018 \u5e7410\u670825\u65e5 | \u5927\u4f1a\u65e5\u7a0b \u7b2c\u4e8c\u5929<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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07:30-17:00<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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07:30-17:00<\/p>\n

\u4f1a\u8bae\u6ce8\u518c<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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08:30-10:00<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u5206\u4f1a\u573a101<\/p>\n

\u80bf\u7624\u514d\u75ab\u65b0\u53d1<\/p>\n

\u5bb4\u4f1a\u5385 1, \u4e09\u5c42<\/p>\n

\u5206\u4f1a\u573a201<\/p>\n

IND\u7533\u62a5<\/p>\n

\u9759\u601d\u5385, \u4e09\u5c42<\/p>\n

\u5206\u4f1a\u573a301<\/p>\n

\u65e9\u671f\u4e34\u5e8a\u8bd5\u9a8c\u6574\u4f53\u7b56\u7565<\/p>\n

\u5bb4\u4f1a\u5385 2, \u4e09\u5c42<\/p>\n

\u5c55\u5546\u5b66\u672f\u4ea4\u6d41\u7814\u8ba8\u4f1a (WPS)<\/p>\n

\u8d35\u5bbe\u623f2, \u4e09\u5c42<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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10:00-10:30<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u8336\u6b47<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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10:30-12:00<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u5206\u4f1a\u573a102<\/p>\n

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\u5bb4\u4f1a\u5385 1, \u4e09\u5c42<\/p>\n

\u5206\u4f1a\u573a202<\/p>\n

IND\u7533\u62a5<\/p>\n

\u9759\u601d\u5385, \u4e09\u5c42<\/p>\n

\u5206\u4f1a\u573a302<\/p>\n

\u5b9e\u7528\u7075\u6d3b\u7684FIH\u8bbe\u8ba1\u53ca\u5e94\u7528<\/p>\n

\u5bb4\u4f1a\u5385 2, \u4e09\u5c42<\/p>\n


<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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12:00-13:30<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u4eba\u624d\u53d1\u5c55\u8bba\u575b & \u5348\u9910<\/p>\n

\u5bb4\u4f1a\u5385 1, \u4e09\u5c42<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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13:30-15:00<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u5206\u4f1a\u573a103<\/p>\n

\u80bf\u65b0\u53d1\u7406\u60f3\u8003\u91cf\u56e0\u7d20\uff08NASH\uff09<\/p>\n

\u5bb4\u4f1a\u5385 1, \u4e09\u5c42<\/p>\n

\u5206\u4f1a\u573a203<\/p>\n

\u65b0\u836f\u9879\u76ee\u542f\u52a8\u524d\u6218\u7565\u8003\u91cf<\/p>\n

\u9759\u601d\u5385, \u4e09\u5c42<\/p>\n

\u5206\u4f1a\u573a303<\/p>\n

POC\uff1a\u7a76\u7adf\u9a8c\u8bc1\u4ec0\u4e48\u548c\u5982\u4f55\u9a8c\u8bc1<\/p>\n

\u5bb4\u4f1a\u5385 2, \u4e09\u5c42
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15:00-15:30<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u8336\u6b47<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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15:30-17:00<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u5206\u4f1a\u573a104<\/p>\n

\u53cc\u7279\u5f02\u6027\u6297\u4f53\u5f00\u53d1<\/p>\n

\u5bb4\u4f1a\u5385 1, \u4e09\u5c42<\/p>\n

\u5206\u4f1a\u573a204<\/p>\n

\u7acb\u9879<\/p>\n

\u9759\u601d\u5385, \u4e09\u5c42<\/p>\n

\u5206\u4f1a\u573a304<\/p>\n

I\u671f\u80bf\u7624\u836f\u7269\u7684\u7814\u53d1<\/p>\n

\u5bb4\u4f1a\u5385 2, \u4e09\u5c42<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u661f\u671f\u4e94 | 2018 \u5e7410\u670826\u65e5 | \u5927\u4f1a\u65e5\u7a0b \u7b2c\u4e09\u5929<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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07:30-17:00<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u4f1a\u8bae\u6ce8\u518c<\/p>\n

\u6ce8\u518c\u53f0, \u4e00\u5c42\u5927\u5802
<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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08:30-10:00<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u5206\u4f1a\u573a105<\/p>\n

\u57fa\u56e0\u6c89\u9ed8\u7597\u6cd5\u7684\u53d1\u5c55<\/p>\n

\u5bb4\u4f1a\u5385 1, \u4e09\u5c42<\/p>\n

\u5206\u4f1a\u573a205<\/p>\n

\u65b0\u53d1\u4e0d\u540c\u7c7b\u578b\u7684\u9879\u76ee\u7acb\u9879<\/p>\n

\u9759\u601d\u5385, \u4e09\u5c42<\/p>\n

\u5206\u4f1a\u573a305<\/p>\n

\u8d62\u5728\u6267\u884c\uff0c \u7814\u53d1\u4f01\u4e1a\uff0c \u7814\u7a76\u8005\uff0c \u4f26\u7406\u59d4\u5458\u4f1a<\/p>\n

CROs\u53caCFDA\u6709\u6548\u7684\u6c9f\u901a<\/p>\n

\u5bb4\u4f1a\u5385 2, \u4e09\u5c42<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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10:00-10:30<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u8336\u6b47<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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10:30-12:00<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u5206\u4f1a\u573a106<\/p>\n

\u7ec6\u80de\u6cbb\u7597\u5b66\u53d1\u5c55<\/p>\n

\u5bb4\u4f1a\u5385 1, \u4e09\u5c42<\/p>\n

\u5206\u4f1a\u573a206<\/p>\n

\u4f01\u4e1a\u7acb\u9879\u7ecf\u9a8c\u5206\u4eab<\/p>\n

\u9759\u601d\u5385, \u4e09\u5c42<\/p>\n

\u5206\u4f1a\u573a306<\/p>\n

\u5b9a\u91cf\u836f\u7406\u5b66\u53ca\u5e94\u7528<\/p>\n

\u5bb4\u4f1a\u5385 2, \u4e09\u5c42<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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12:00-13:30<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u4eba\u624d\u53d1\u5c55\u8bba\u575b & \u5348\u9910<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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13:30-15:00<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u5206\u4f1a\u573a107<\/p>\n

ADC\u6297\u4f53\u5076\u8054\u836f\u7269<\/p>\n

\u5bb4\u4f1a\u5385 1, \u4e09\u5c42<\/p>\n

\u5206\u4f1a\u573a207<\/p>\n

\u4e1a\u52a1\u62d3\u5c55\u6295\u8d44\u8bba\u575b<\/p>\n

\u9759\u601d\u5385, \u4e09\u5c42<\/p>\n

\u5206\u4f1a\u573a307<\/p>\n

\u9ad8\u6548\u7075\u6d3b\u7684\u6570\u636e\u7ba1\u7406\u548c\u7edf\u8ba1\u5206\u6790<\/p>\n

\u5bb4\u4f1a\u5385 2, \u4e09\u5c42
<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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15:00-15:30<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u8336\u6b47<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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15:30-17:00<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u5206\u4f1a\u573a108<\/p>\n

\u4eba\u5de5\u667a\u80fd\u5728\u836f\u7269\u7814\u53d1\u4e2d\u7684\u8fd0\u7528<\/p>\n

\u5bb4\u4f1a\u5385 1, \u4e09\u5c42<\/p>\n

\u5206\u4f1a\u573a208<\/p>\n

\u4e1a\u52a1\u62d3\u5c55\u6295\u8d44\u8bba\u575b<\/p>\n

\u9759\u601d\u5385, \u4e09\u5c42<\/p>\n

\u5206\u4f1a\u573a308<\/p>\n

\u751f\u7269\u6807\u5fd7\u7269\u7814\u53d1\u53ca\u5e94\u7528<\/p>\n

\u5bb4\u4f1a\u5385 2, \u4e09\u5c42
<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u4f1a\u8bae\u7ed3\u675f\uff0c\u5927\u5df4\u9001\u5f80\u6307\u5b9a\u706b\u8f66\u7ad9\u3001\u673a\u573a<\/span><\/p>\n

\u8def\u7ebf\u4e00\uff1a\u9152\u5e97 >> \u9ad8\u94c1\u82cf\u5dde\u56ed\u533a\u7ad9 >> \u82cf\u5dde\u7ad9<\/p>\n

\u8def\u7ebf\u4e8c\uff1a\u9152\u5e97 >> \u9ad8\u94c1\u82cf\u5dde\u5317\u7ad9<\/p>\n

\u8def\u7ebf\u4e09\uff1a\u9152\u5e97 >> \u4e0a\u6d77\u8679\u6865\u706b\u8f66\u7ad9 >> \u4e0a\u6d77\u8679\u6865\u673a\u573a T2 >> \u4e0a\u6d77\u8679\u6865\u673a\u573a T1<\/p>\n

\u6bcf\u6761\u8def\u7ebf\u4e00\u8d9f\u73ed\u8f66\uff0c\u5ea7\u4f4d\u6709\u9650\uff0c\u5148\u5230\u5148\u5f97<\/p>\n

\u4e3b\u65e8\u6f14\u8bb2<\/strong><\/span><\/p>\n

\u5609\u5bbe\u4e00<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\"\u6536\u85cf|\u6211\u4eec\u4e3a\u60a8\u89c4\u5212\u4e86\u4e09\u5929\u6700\u6709\u4ef7\u503c\u7684\u521b\u65b0\u836f\u5927\u4f1a<\/section>\n<\/section>\n<\/section>\n
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Muthiah\uff08Mano\uff09Manoharan  \u535a\u58eb<\/p>\n

\u9ad8\u7ea7\u526f\u603b\u88c1\u517c\u6770\u51fa\u7814\u7a76\u79d1\u5b66\u5bb6<\/p>\n

Alnylam \u5236\u836f\u516c\u53f8<\/p>\n

\u4e3b\u65e8\u6f14\u8bb2\uff1a<\/p>\n

RNAi \u7597\u6cd5\uff1a\u5168\u65b0\u4e00\u7c7b\u7684\u836f\u7269<\/p>\n

2018\u5e748\u670810\u65e5\u7f8e\u56fdFDA\u6279\u51c6\u4e86Alnylam\u5236\u836f\u516c\u53f8\u7684\u5168\u65b0\u4e00\u7c7bRNAi\u836f\u7269 Patisiran  \u7528\u4e8e\u6cbb\u7597\u9057\u4f20\u6027ATTR\u578b\u6dc0\u7c89\u6837\u53d8\u7684\u591a\u53d1\u6027\u795e\u7ecf\u75c5\u53d8\u3002<\/p>\n

2018\u5e748\u670830\u65e5Patisiran  \u4f5c\u4e3a\u7b2c\u4e00\u4e2a\u5168\u65b0\u7684 RANi \u7684\u836f\u7269\u5728\u6b27\u76df\u6279\u51c6\u3002<\/p>\n

Muthiah\uff08Mano\uff09Manoharan\u535a\u58eb\u662f\u7f8e\u56fd\u9a6c\u8428\u8bf8\u585e\u5dde\u5251\u6865\u5e02Alnylam\u5236\u836f\u516c\u53f8\u7684\u9ad8\u7ea7\u526f\u603b\u88c1\u517c\u6770\u51fa\u7814\u7a76\u79d1\u5b66\u5bb6\u3002 Manoharan\u535a\u58eb\u4e8e2003\u5e74\u52a0\u5165Alnylam\u3002\u4ed6\u5728Alnylam\u5efa\u7acb\u4e86\u5316\u5b66\u5c0f\u7ec4\uff0c\u5e76\u9996\u521b\u4e86\u57fa\u4e8eRNA\u5e72\u6270\u7684\u4eba\u7c7b\u7597\u6cd5\u3002 Manoharan\u535a\u58eb\u4f5c\u4e3a\u5be1\u6838\u82f7\u9178\u5316\u5b66\u4fee\u9970\uff0c\u7ed3\u5408\u5316\u5b66\u4ee5\u53ca\u9012\u9001\u5e73\u53f0\uff08\u8102\u8d28\u7eb3\u7c73\u7c92\u5b50\uff0c\u805a\u5408\u7269\u7f00\u5408\u7269\u548c\u590d\u5408\u7269\u5f62\u6210\u7b56\u7565\uff09\u7b49\u9886\u57df\u7684\u4e16\u754c\u9886\u5148\u5316\u5b66\u5bb6\uff0c\u62e5\u6709\u6770\u51fa\u7684\u804c\u4e1a\u751f\u6daf\u3002 Manoharan\u535a\u58eb\u7684\u7814\u7a76\u5c0f\u7ec4\u53d1\u73b0\u5e76\u8bc1\u660e\u4e86GalNAc\u5076\u8054\u5be1\u6838\u82f7\u9178\u5728\u4eba\u7c7b\u6cbb\u7597\u65b9\u9762\u7684\u5e94\u7528\u3002\u4ed6\u524d\u540e\u5171\u53d1\u8868\u4e86200\u591a\u79cd\u520a\u7269\uff08\u8fd13.7\u4e07\u6b21\u88ab\u5f15\u7528\uff0ch-index 85, i10-index 329\uff09\u548c400\u591a\u7bc7\u6458\u8981\uff0c\u540c\u65f6\u62e5\u6709\u8d85\u8fc7225\u9879\u7f8e\u56fd\u4e13\u5229\u3002\u5728\u52a0\u5165Alnylam\u4e4b\u524d\uff0cManoharan\u535a\u58eb\u662fIonis \u5236\u836f\u516c\u53f8\u5728\u5be1\u6838\u82f7\u9178\u7597\u6cd5\u9886\u57df\u7684\u77e5\u540d\u7814\u7a76\u5458\u3002\u7531\u4e8e\u4ed6\u7684\u8d21\u732e\uff0c\u4ed6\u57282007\u5e74\u83b7\u5f97\u7f8e\u56fd\u5316\u5b66\u5b66\u4f1a\u78b3\u6c34\u5316\u5408\u7269\u5316\u5b66\u5206\u90e8\u7684M. L. Wolfrom\u5956\u3002Manoharan\u535a\u58eb\u5728\u5317\u5361\u7f57\u6765\u7eb3\u5927\u5b66\u6559\u5802\u5c71\u5206\u6821\u4e0eErnest L. Eliel\u6559\u6388\u5171\u540c\u83b7\u5f97\u5316\u5b66\u535a\u58eb\u5b66\u4f4d\uff0c\u5e76\u4e0eJohn A. Gerlt\u6559\u6388\u5728\u8036\u9c81\u5927\u5b66\u548c\u9a6c\u91cc\u5170\u5927\u5b66\u8fdb\u884c\u535a\u58eb\u540e\u7814\u7a76\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u5609\u5bbe\u4e8c<\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\"\u6536\u85cf|\u6211\u4eec\u4e3a\u60a8\u89c4\u5212\u4e86\u4e09\u5929\u6700\u6709\u4ef7\u503c\u7684\u521b\u65b0\u836f\u5927\u4f1a<\/section>\n<\/section>\n<\/section>\n
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\u5f90\u5c91 \u535a\u58eb<\/p>\n

\u79d1\u6280\u603b\u76d1<\/p>\n

\u5b89\u8fdb\u516c\u53f8R&D<\/p>\n

\u4e3b\u65e8\u6f14\u8bb2\uff1a<\/p>\n

\u201c\u4ece\u5b9e\u9a8c\u5ba4\u5230\u75c5\u5e8a\u201d – AimovigTM (erenumab-aooe)  FDA\u6279\u51c6\u7684\u9996\u4e2a\u6cbb\u7597\u504f\u5934\u75db\u7684\u6297\u4f53\u836f<\/p>\n

2018\u5e745\u670817\u65e5\uff0c\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u6279\u51c6AimovigTM \uff08erenumab-aooe\uff09\u7528\u4e8e\u6210\u4eba\u504f\u5934\u75db\u7684\u9884\u9632\u6027\u6cbb\u7597, \u662fFDA\u6279\u51c6\u7684\u7b2c\u4e00\u4e2a\u9488\u5bf9GPCR\u9776\u70b9\u7684\u6297\u4f53\u836f\u7269\u3002AimovigTM\u662fFDA\u6279\u51c6\u7684\u9996\u4e2a\u9884\u9632\u6027\u6cbb\u7597\u504f\u5934\u75db\u7684\u836f\u7269\uff0c\u8be5\u836f\u662f\u901a\u8fc7\u963b\u65ad\u964d\u9499\u7d20\u57fa\u56e0\u76f8\u5173\u591a\u80bd\uff08\u4e00\u79cd\u5728\u504f\u5934\u75db\u4e2d\u53d1\u6325\u91cd\u8981\u4f5c\u7528\u7684\u5206\u5b50\uff09\u7684\u6d3b\u6027\u800c\u53d1\u6325\u4f5c\u7528\u7684\u4e00\u7c7b\u65b0\u836f\u3002<\/p>\n

\u504f\u5934\u75db\u662f\u4e16\u754c\u4e0a\u7b2c\u4e09\u5927\u6d41\u884c\u75be\u75c5\uff0c\u4e5f\u662f\u5168\u7403\u7b2c\u516d\u5927\u81f4\u6b8b\u75be\u75c5\uff0c\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\uff08WHO\uff09\u4e5f\u5c06\u504f\u5934\u75db\u5217\u4e3a\u6700\u6076\u5316\u7684\u75be\u75c5\u4e4b\u4e00\u3002\u636e\u7814\u7a76\u8868\u660e\u504f\u5934\u75db\u7684\u5168\u7403\u53d1\u75c5\u7387\u5728\u5973\u6027\u548c\u7537\u6027\u4e2d\u5206\u522b\u662f 18% \u548c6%\uff0c \u800c\u7f8e\u56fd\u4e00\u5e74\u6709\u591a\u8fbe3900\u4e07\u4eba\u88ab\u504f\u5934\u75db\u6298\u78e8\u3002<\/p>\n

 FDA\u6279\u51c6AimovigTM\u5bf9\u60a3\u8005\u548c\u533b\u751f\u6765\u8bf4\u662f\u5f97\u5230\u4e86\u4e00\u79cd\u671f\u5f85\u5df2\u4e45\u7684\u91cd\u8981\u7684\u9884\u9632\u504f\u5934\u75db\u6cbb\u7597\u65b0\u65b9\u6848\u3002<\/p>\n

 DIA \u4e2d\u56fd\u5f88\u8363\u5e78\u5730\u9080\u8bf7\u5230\u5f90\u5c91\u535a\u58eb\u5c31\u504f\u5934\u75db\u6cbb\u7597\u7684\u8fd9\u4e00\u91cd\u8981\u7684\u65b0\u836f\u7a81\u7834\u53d1\u8868\u6f14\u8bb2\u3002<\/p>\n

 \u5f90\u5c91\u535a\u58eb\u73b0\u4efb\u5b89\u8fdbR&D\u7684\u79d1\u6280\u603b\u76d1\uff0c\u8d1f\u8d23\u504f\u5934\u75db\u548c\u9547\u75db\u7684\u7814\u7a76\u3002\u5979\u62e5\u670920\u591a\u5e74\u7684\u4f20\u7edf\u548c\u751f\u7269\u5236\u836f\u7ecf\u9a8c\uff0c\u662fAimovigTM\u7684\u6982\u5ff5\u751f\u6210\u8005\u548c\u4e3b\u8981\u53d1\u660e\u8005\uff0c\u4e34\u5e8a\u524d\u7814\u7a76\u7684\u4e3b\u5bfc\u8005\u5e76\u53c2\u4e0e\u4ece\u4ea7\u54c1\u5f00\u53d1\u5230\u4ea7\u54c1\u4e0a\u5e02\u7684\u603b\u8fc7\u7a0b\u3002\u5f90\u5c91\u535a\u58eb\u540c\u65f6\u4e5f\u662f\u591a\u9879\u4e13\u5229\u548c\u4e13\u5229\u7533\u8bf7\u7684\u5171\u540c\u53d1\u660e\u8005\uff0c\u76ee\u524d\u8fd8\u6709\u4e24\u9879\u4ea7\u54c1\u6b63\u5728\u8fdb\u884c\u4e34\u5e8a\u5f00\u53d1\u3002\u5979\u7684\u65e9\u671f\u79d1\u7814\u6210\u679c\u5305\u62ec\u6cbb\u7597\u7cbe\u795e\u5206\u88c2\u75c7\u7684ABILIFY\uff08\u963f\u7acb\u54cc\u5511\uff09\u548c\u6cbb\u7597\u7761\u7720\u969c\u788d\u7684HETLIOZ (tasimelteon)\u3002\u5f90\u5c91\u535a\u58eb\u62e5\u6709\u4f0a\u5229\u8bfa\u5dde\u5927\u5b66\u7684\u836f\u7406\u5b66\u535a\u58eb\u5b66\u4f4d\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u7ec4\u59d4\u4f1a\u4e3b\u5e2d<\/strong><\/span><\/p>\n

\u5f20\u660e\u5f3a \u535a\u58eb<\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
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\"\u6536\u85cf|\u6211\u4eec\u4e3a\u60a8\u89c4\u5212\u4e86\u4e09\u5929\u6700\u6709\u4ef7\u503c\u7684\u521b\u65b0\u836f\u5927\u4f1a<\/section>\n<\/section>\n<\/section>\n
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\u5927\u4f1a\u4e3b\u5e2d<\/p>\n

\u7f8e\u56fd\u5b89\u8fdb\u516c\u53f8 \u5168\u7403\u7814\u53d1\u526f\u603b\u88c1<\/p>\n


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Sorrento Therapeutics<\/p>\n

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\u62a5\u540d\u8054\u7cfb\u4eba: \u6768\u6587\u6021<\/p>\n

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\u7535\u8bdd: +86 21 6042 9857<\/p>\n

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2018 DIA\u4e2d\u56fd\u7b2c\u56db\u5c4a\u836f\u7269\u7814\u53d1\u521b\u65b0\u5927\u4f1a<\/p>\n

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<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

\u8f6c\u8f7d\u6765\u6e90\uff1aDIA\u8ba2\u9605\u53f7 \u4f1a\u8bae \u6d41\u7a0b \u661f\u671f\u4e09 | 2018 \u5e7410\u670824\u65e5 | \u5927\u4f1a\u65e5\u7a0b \u7b2c\u4e00\u5929 07:30-1 […]<\/p>\n","protected":false},"author":1,"featured_media":67691,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/67690"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=67690"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/67690\/revisions"}],"predecessor-version":[{"id":67710,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/67690\/revisions\/67710"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/67691"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=67690"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=67690"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=67690"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}