{"id":73149,"date":"2018-12-03T01:00:00","date_gmt":"2018-12-07T05:13:12","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/12\/07\/41efb334d3\/"},"modified":"2018-12-07T13:13:15","modified_gmt":"2018-12-07T05:13:15","slug":"41efb334d3","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/73149\/","title":{"rendered":"CRI+IQVIA\uff1a\u6297PD-1\/PD-L1\u5236\u5242\u76842250\u4e2a\u4e34\u5e8a\u73b0\u72b6"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"text-align: center;\"><span style=\"color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 14px;letter-spacing: 0.544px;text-align: center;background-color: rgb(255, 255, 255);\">\u70b9\u51fb\u4e0a\u65b9\u7684&nbsp;&nbsp;\u25b2&nbsp;\u6dfb\u52a0\u5173\u6ce8<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;font-family: \u6977\u4f53;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u524d\u8a00\uff1a11\u670828\u65e5<\/span><em style=\"max-width: 100%;font-size: 13.3333px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;font-family: \u6977\u4f53;color: rgb(85, 85, 85);background-image: initial;background-position: initial;background-size: initial;background-repeat: initial;background-attachment: initial;background-origin: initial;background-clip: initial;box-sizing: border-box !important;overflow-wrap: break-word !important;\">Nature Reviews Drug Discovery<\/span><\/em><span style=\"max-width: 100%;font-size: 12px;color: rgb(85, 85, 85);background-image: initial;background-position: initial;background-size: initial;background-repeat: initial;background-attachment: initial;background-origin: initial;background-clip: initial;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">&nbsp;<\/span><span style=\"max-width: 100%;font-family: \u6977\u4f53;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u520a\u767b\u4e86CRI\u548cIQVIA\u56e2\u961f\u9488\u5bf9\u6297PD-1\/PD-L1\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u7684\u4e34\u5e8a\u7814\u7a76\u73b0\u72b6\u7684\u6700\u65b0\u5168\u9762\u5206\u6790\u3002<\/span><span style=\"max-width: 100%;font-family: \u6977\u4f53;background-image: initial;background-position: initial;background-size: initial;background-repeat: initial;background-attachment: initial;background-origin: initial;background-clip: initial;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u8fd9\u7bc7\u6587\u7ae0\u7740\u91cd\u4e8e\u76ee\u524d\u4e34\u5e8a\u7814\u7a76\u7684\u8d8b\u52bf\u5e76\u4e14\u786e\u8ba4\u672a\u6765\u5728\u53d7\u8bd5\u8005\u62db\u52df\u4e0a\u53ef\u80fd\u5b58\u5728\u7684\u6311\u6218\u3002\u76ee\u524d\u76842250\u4e2aPD-1\/PD-L1\u4e34\u5e8a\uff08\u76f8\u6bd4\u8fc7\u53bb1\u5e74\u589e\u52a0748\u4e2a\uff09\u4e2d\u7edd\u5927\u591a\u6570\u90fd\u662f\u8bc4\u4f30\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u8054\u5408\u5176\u5b83\u6cbb\u7597\u7684\u65b9\u6848\uff0c\u81f3\u5c11\u9700\u898138\u4e07\u540d\u53d7\u8bd5\u8005\u6765\u5b8c\u6210\u6240\u6709\u4e34\u5e8a\uff0c\u8fd1\u6765\u60a3\u8005\u7684\u62db\u52df\u901f\u5ea6\u6025\u5267\u4e0b\u964d\u3002<\/span><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"\"      style=\"box-sizing: border-box !important;overflow-wrap: break-word !important;width: 677px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/4-1544159593.png\" alt=\"CRI+IQVIA\uff1a\u6297PD-1\/PD-L1\u5236\u5242\u76842250\u4e2a\u4e34\u5e8a\u73b0\u72b6\" title=\"CRI+IQVIA\uff1a\u6297PD-1\/PD-L1\u5236\u5242\u76842250\u4e2a\u4e34\u5e8a\u73b0\u72b6\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(85, 85, 85);font-family: \u6977\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">&nbsp;<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"\"      style=\"box-sizing: border-box !important;overflow-wrap: break-word !important;width: 383px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/2-1544159593.jpg\" alt=\"CRI+IQVIA\uff1a\u6297PD-1\/PD-L1\u5236\u5242\u76842250\u4e2a\u4e34\u5e8a\u73b0\u72b6\" title=\"CRI+IQVIA\uff1a\u6297PD-1\/PD-L1\u5236\u5242\u76842250\u4e2a\u4e34\u5e8a\u73b0\u72b6\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u6977\u4f53;color: rgb(85, 85, 85);background-image: initial;background-position: initial;background-size: initial;background-repeat: initial;background-attachment: initial;background-origin: initial;background-clip: initial;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u6b63\u6587\uff1a<\/span><\/strong><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;font-family: \u6977\u4f53;color: rgb(85, 85, 85);background-image: initial;background-position: initial;background-size: initial;background-repeat: initial;background-attachment: initial;background-origin: initial;background-clip: initial;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u81ea\u4ece\u9996\u4e2a\u9776\u5411PD-1\u7684\u5355\u6297\u2014\u2014nivolumab\u7684\u4e34\u5e8a\u57282006\u5e74\u5f00\u5c55\u4ee5\u6765\uff0c\u5df2\u7ecf\u9646\u7eed\u67096\u4e2a\u9776\u5411PD-1\u53ca\u5176\u914d\u4f53PD-L1\u7684\u6297\u4f53\u88abFDA\u6279\u51c6\u7528\u4e8e\u6cbb\u759714\u79cd\u7c7b\u578b\u80bf\u7624\u53ca\u4e00\u4e2a\u4e0d\u4ee5\u7ec4\u7ec7\u5b66\u533a\u5206\u7684\u591a\u764c\u79cd\u9002\u5e94\u75c7\u3002\u6297PD-1\/PD-L1\u7684\u5236\u5242\u5c31\u6b64\u4f5c\u4e3a\u80bf\u7624\u514d\u75ab\u9886\u57df\u7684\uff0c\u6b63\u5728\u5f00\u5c55\u7684\u8bc4\u4f30\u6297PD-1\/PD-L1\u5236\u5242\u7684\u4e34\u5e8a\u6570\u76ee\u4e5f\u4ece2006\u5e74\u76841\u5267\u589e\u81f32018\u5e749\u6708\u4efd\u76842250\u3002\u764c\u75c7\u7814\u7a76\u6240\uff08CRI\uff09\u5206\u6790\u4e86\u65e8\u5728\u8bc4\u4f30\u8fd9\u4e9b\u5236\u5242\u7684\u4e34\u5e8a\u8bd5\u9a8c\u7684\u73b0\u72b6\uff0c\u5e76\u4e0e17\u5e74\u505a\u7684\u8c03\u67e5\u505a\u4e86\u6bd4\u8f83<\/span><span style=\"max-width: 100%;font-family: \u6977\u4f53;background-image: initial;background-position: initial;background-size: initial;background-repeat: initial;background-attachment: initial;background-origin: initial;background-clip: initial;font-size: 12px;color: rgb(0, 209, 0);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u3010\u6ce8\uff1a\u4e0a\u6b21\u8c03\u67e5\u53ef\u4ee5\u67e5\u770b\u4e4b\u524d\u63a8\u9001\uff1a<\/span><span style=\"max-width: 100%;font-size: 12px;font-family: \u6977\u4f53;color: rgb(85, 85, 85);background-image: initial;background-position: initial;background-size: initial;background-repeat: initial;background-attachment: initial;background-origin: initial;background-clip: initial;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzA4NDc5MDQwOA==&amp;mid=2448571549&amp;idx=1&amp;sn=adc139e06380dc1c04d468b0f7ad8f78&amp;chksm=8be7417abc90c86c5e345372d5cf7e84212cfa54ea1aaab3ccbd23a60706a198db350ec872d2&amp;token=1141798023&amp;lang=zh_CN&amp;scene=21#wechat_redirect\" target=\"_blank\" style=\"color: rgb(87, 107, 149);-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(2, 30, 170);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5168\u7403\u514d\u75ab\u6cbb\u7597\u7edf\u8ba1\u56fe\uff08\u6765\u81eaCRI\uff09<\/span><\/strong><\/a><\/span><span style=\"max-width: 100%;font-family: \u6977\u4f53;background-image: initial;background-position: initial;background-size: initial;background-repeat: initial;background-attachment: initial;background-origin: initial;background-clip: initial;font-size: 12px;color: rgb(0, 209, 0);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u3011<\/span><span style=\"max-width: 100%;font-size: 12px;font-family: \u6977\u4f53;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u6977\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">&nbsp;<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u6977\u4f53;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u81ea\u4ece\u4e0a\u6b21\u8c03\u67e5\u4ee5\u6765\u81f32018\u5e749\u6708\uff0c\u603b\u5171\u65b0\u589e\u4e86748\u4e2a\u65b0\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u6b63\u5728\u8fdb\u884c\u4e2d\u7684\u4e34\u5e8a\u603b\u6570\u8fbe\u52302250\u4e2a\u3002\u5728\u8fd9\u4e2d\u95f4\u67091716\u4e2a\u662f<\/span><span style=\"max-width: 100%;font-family: \u6977\u4f53;color: rgb(85, 85, 85);background-image: initial;background-position: initial;background-size: initial;background-repeat: initial;background-attachment: initial;background-origin: initial;background-clip: initial;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u6297PD-1\/PD-L1\u5236\u5242\u8054\u5408\u5176\u4ed6\u6cbb\u7597\u7684\u65b9\u6848\u3002<\/span><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"\"      style=\"box-sizing: border-box !important;overflow-wrap: break-word !important;width: 554px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/5-1544159593.jpg\" alt=\"CRI+IQVIA\uff1a\u6297PD-1\/PD-L1\u5236\u5242\u76842250\u4e2a\u4e34\u5e8a\u73b0\u72b6\" title=\"CRI+IQVIA\uff1a\u6297PD-1\/PD-L1\u5236\u5242\u76842250\u4e2a\u4e34\u5e8a\u73b0\u72b6\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u6977\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5c3d\u7ba1\u76ee\u524dFDA\u53ea\u6279\u51c6\u4e24\u79cd\u5f62\u5f0f\u7684\u8054\u5408\u6cbb\u7597\uff08\u5206\u522bnivolumab+iplimumab\u3001pembrolizumab+chemo\uff09\uff0c\u4f46\u662f\u5e76\u4e0d\u59a8\u788d\u73b0\u5728\u6b63\u5728\u8bc4\u4f30\u6297PD-1\/PD-L1\u5236\u5242\u548c240\u591a\u79cd\u4e0d\u540c\u9776\u70b9\u7684\u8054\u5408\u6cbb\u7597\uff08\u4e0b\u9762\u7b2c\u4e00\u5e45\u56fe\uff09\uff0c\u800c\u5728\u4e0a\u6b21\u7edf\u8ba1\u4e2d\u8fd9\u4e2a\u6570\u5b57\u53ea\u670975\uff08\u4e0b\u9762\u7b2c\u4e8c\u5e45\u56fe\uff09\u3002<\/span><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u6977\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u800c\u5728\u8fd91716\u4e2a\u7814\u7a76\u4e2d\uff0c\u6709339\u4e2a\u662f\u6297CTLA4\u5355\u6297\u7684\u8054\u5408\uff0c\u4f7f\u5f97CTAL4\u6210\u4e3a\u6700\u5e38\u89c1\u7684\u8054\u5408\u6cbb\u7597\u7684\u9776\u70b9\uff08\u4e0b\u9762\u7b2c\u4e00\u5e45\u56fe\uff09\u3002\u5176\u4f59\u5e38\u89c1\u7684\u8054\u5408\u5305\u62ec\u5316\u7597\uff08283\u4e2a\uff09\u3001\u653e\u7597\uff08114\u4e2a\uff09\u3001\u6297\u8840\u7ba1\u751f\u6210\uff08VEGFA 52+VEGFRs 11\uff09\u548c\u540c\u6b65\u653e\u5316\u7597\uff0858\u4e2a\uff09<span style=\"max-width: 100%;color: rgb(0, 176, 80);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u3010\u6ce8\uff1a\u6b64\u5904\u6392\u5e8f\u76f8\u8f83\u539f\u6587\u505a\u4fee\u6539\uff0c\u5408\u5e76VEGFA\u548cVEGFRs\uff1b\u53e6\u5916\u76f8\u6bd4\u8f83\u53ef\u4ee5\u770b\u51fa\u8fd9\u51e0\u7c7b\u65b9\u6848\u7684\u4e34\u5e8a\u589e\u901f\u975e\u5e38\u9ad8\u3011<\/span>\u3002\u6709\u8da3\u7684\u662f\uff0c\u53bb\u5e74\u7edf\u8ba1\u7684\u6570\u636e\u4e2d\u8054\u5408IDO-1\u548cPARP\u7684\u4e34\u5e8a\u5206\u522b25\u548c23\u4e2a\uff0c\u800c\u4eca\u5e74\u662f40\u548c32\u4e2a\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"\"      style=\"box-sizing: border-box !important;overflow-wrap: break-word !important;width: 545px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/9-1544159594.jpg\" alt=\"CRI+IQVIA\uff1a\u6297PD-1\/PD-L1\u5236\u5242\u76842250\u4e2a\u4e34\u5e8a\u73b0\u72b6\" title=\"CRI+IQVIA\uff1a\u6297PD-1\/PD-L1\u5236\u5242\u76842250\u4e2a\u4e34\u5e8a\u73b0\u72b6\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"\"      style=\"box-sizing: border-box !important;overflow-wrap: break-word !important;width: 554px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/5-1544159594.jpg\" alt=\"CRI+IQVIA\uff1a\u6297PD-1\/PD-L1\u5236\u5242\u76842250\u4e2a\u4e34\u5e8a\u73b0\u72b6\" title=\"CRI+IQVIA\uff1a\u6297PD-1\/PD-L1\u5236\u5242\u76842250\u4e2a\u4e34\u5e8a\u73b0\u72b6\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u6977\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">&nbsp;<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u6977\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u53e6\u5916\u518d\u6765\u770b\u5355\u836f\u53ca\u8054\u5408\u6cbb\u7597\u7684\u80bf\u7624\u7c7b\u578b\uff0c\u4e34\u5e8a\u6570\u524d\u4e94\u5927\uff1a\u80ba\u764c\uff08253\u4e2a\uff09\u3001\u9ed1\u8272\u7d20\u7624\uff08139\u4e2a\uff09\u3001\u4e73\u817a\u764c\uff08106\u4e2a\uff09\u3001\u6dcb\u5df4\u7624\uff0899\u4e2a\uff09\u548c\u5934\u9888\u90e8\u764c\uff0872\u4e2a\uff09\u3002\u9700\u8981\u6307\u51fa\u7684\u662f\u9ed1\u8272\u7d20\u7624\u65b0\u5f00\u7684\u4e34\u5e8a\u6570\u8fd1\u6765\u4e0b\u964d\uff0c\u4e3b\u8981\u53ef\u80fd\u56e0\u4e3anivolumab\u8054\u5408ipilumumab\u5df2\u7ecf\u83b7\u6279\uff0c\u9ad8\u8fbe58%\u7684ORR\u53ef\u80fd\u8ba9\u5176\u5b83\u7684\u65b0\u7684\u8054\u5408\u65b9\u6848\u5f88\u96be\u8d85\u8d8a\uff08\u89c1\u4e0b\u56fe\uff0c\u6309\u80bf\u7624\u7c7b\u578b\u5212\u5206\u7684\u4e34\u5e8a\u6570\u76ee\uff09\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"\"      style=\"box-sizing: border-box !important;overflow-wrap: break-word !important;width: 553px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/0-1544159594.jpg\" alt=\"CRI+IQVIA\uff1a\u6297PD-1\/PD-L1\u5236\u5242\u76842250\u4e2a\u4e34\u5e8a\u73b0\u72b6\" title=\"CRI+IQVIA\uff1a\u6297PD-1\/PD-L1\u5236\u5242\u76842250\u4e2a\u4e34\u5e8a\u73b0\u72b6\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u6977\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">&nbsp;<\/span><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u6977\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u6240\u6709\u8fd9\u4e9b\u4e34\u5e8a\u52a0\u5728\u4e00\u8d77\u603b\u5171\u9700\u8981\u62db\u52df38.09\u4e07\u540d\u53d7\u8bd5\u8005\uff0c\u8fc7\u53bb5\u5e74\u8fd9\u4e2a\u9700\u6c42\u91cf\u589e\u957f\u5f88\u5927\u3002\u4f8b\u5982\uff0c\u4e0b\u56fe\u4e2d\u7eb5\u5750\u6807\u5bf9\u5e94\u5f53\u5e74\u65b0\u5f00\u4e34\u5e8a\u9700\u8981\u62db\u52df\u7684\u60a3\u8005\u6570\uff0c\u4f8b\u598217\u5e74\u9700\u8981\u62db\u52df105489\u4eba\uff0c18\u5e74\u622a\u6b62\u81f39\u6708\u9700\u8981\u62db\u52df72678\u4eba\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"\"      style=\"box-sizing: border-box !important;overflow-wrap: break-word !important;width: 554px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/5-1544159595.png\" alt=\"CRI+IQVIA\uff1a\u6297PD-1\/PD-L1\u5236\u5242\u76842250\u4e2a\u4e34\u5e8a\u73b0\u72b6\" title=\"CRI+IQVIA\uff1a\u6297PD-1\/PD-L1\u5236\u5242\u76842250\u4e2a\u4e34\u5e8a\u73b0\u72b6\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u6977\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u57fa\u4e8e\u62db\u52df\u9700\u6c42\u7684\u91cd\u8981\u6027\uff0c\u7814\u7a76\u4eba\u5458\u5206\u6790\u4e86533\u4e2aPD-1\/PD-L1\u7684\u4e34\u5e8a\u548c2781\u4e2a\u6297\u80bf\u7624\u9886\u57df\u975ePD-1\/PD-L1\u7684\u4e34\u5e8a\u4e2d\u53ef\u4ee5\u67e5\u5230\u7684\u62db\u52df\u6570\u636e\uff0c\u53d1\u73b0\u5728\u8fc7\u53bb4\u5e74PD-1\/PD-L1\u7684\u4e34\u5e8a\u4e2d\u60a3\u8005\u7684\u62db\u52df\u901f\u5ea6\u5feb\u4e8e\u5176\u5b83\u80bf\u7624\u836f\u7269\u4e34\u5e8a\u3002\u4f46\u662f\u8fd1\u6765\u62db\u52df\u901f\u5ea6\u5df2\u7ecf\u663e\u8457\u4e0b\u964d\uff0c\u4ece14\u5e74\u7684\u6bcf\u4e2a\u4e2d\u5fc3\u6bcf\u4e2a\u67081.15\u540d\u60a3\u8005\u4e0b\u6ed1\u523018\u5e74\u6bcf\u4e2a\u4e2d\u5fc3\u6bcf\u4e2a\u67080.34\u540d\u60a3\u8005<span style=\"max-width: 100%;color: rgb(0, 176, 80);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u3010\u6ce8\uff1a\u611f\u89c9\u5355\u4e00\u6216\u8005\u540c\u53e3\u5f84\u7684\u4e2d\u5fc3\u62db\u52df\u901f\u5ea6\u5e94\u8be5\u4e0b\u6ed1\u6ca1\u8fd9\u4e48\u660e\u663e\uff0c\u6bd5\u7adf\u4e2d\u5fc3\u6570\u91cf\u5e94\u8be5\u4e5f\u589e\u52a0\u4e86\u3011<\/span>\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"\"      style=\"box-sizing: border-box !important;overflow-wrap: break-word !important;width: 397px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/4-1544159595.jpg\" alt=\"CRI+IQVIA\uff1a\u6297PD-1\/PD-L1\u5236\u5242\u76842250\u4e2a\u4e34\u5e8a\u73b0\u72b6\" title=\"CRI+IQVIA\uff1a\u6297PD-1\/PD-L1\u5236\u5242\u76842250\u4e2a\u4e34\u5e8a\u73b0\u72b6\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u6977\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u8fd9\u63d0\u793a\u672a\u6765\u8054\u5408\u6cbb\u7597\u5728\u60a3\u8005\u62db\u52df\u4e0a\u53ef\u80fd\u4f1a\u53d7\u5230\u6311\u6218\uff0c\u5c24\u5176\u662f\u4e00\u4e9b\u7279\u5b9a\u7684\u80bf\u7624\u7c7b\u578b\uff0c\u4e0b\u56fe\u6bd4\u8f83\u4e86\u4e0a\u6587\u63d0\u53ca533\u4e2a\u4e34\u5e8a\u4e2d\u4e0d\u540c\u80bf\u7624\u7c7b\u578b\u5bf9\u5e94\u7684\u4e34\u5e8a\u6570\u548c\u62db\u52df\u901f\u5ea6\u7684\u5173\u7cfb\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"\"      style=\"box-sizing: border-box !important;overflow-wrap: break-word !important;width: 554px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/2-1544159595.jpg\" alt=\"CRI+IQVIA\uff1a\u6297PD-1\/PD-L1\u5236\u5242\u76842250\u4e2a\u4e34\u5e8a\u73b0\u72b6\" title=\"CRI+IQVIA\uff1a\u6297PD-1\/PD-L1\u5236\u5242\u76842250\u4e2a\u4e34\u5e8a\u73b0\u72b6\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft 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!important;\">\u603b\u7ed3\uff1a<\/span><\/strong><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 17px;letter-spacing: 0.544px;text-align: justify;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u6977\u4f53;font-size: 12px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u76f8\u6bd4\u4e0a\u6b21\u7edf\u8ba1\uff0c\u6700\u65b0\u7684\u4e34\u5e8a\u660e\u663e\u6269\u5bb9\uff1a\u65b0\u589e748\u4e2a\u4e34\u5e8a\u8bd5\u9a8c\u300175\u4e2a\u65b0\u9776\u70b9\u5e76\u4e14\u9700\u8981\u589e\u52a010\u4e07\u540d\u53d7\u8bd5\u8005\u3002\u8fc7\u53bb1\u5e74FDA\u6279\u51c6\u4e86\u6297PD-1\/PD-L1\u5236\u5242\u768413\u4e2a\u9002\u5e94\u75c7\uff0c\u5305\u62ec\u4e861\u4e2a\u65b0\u7684\u836f\u7269cemiplimab\u3002\u5982\u6b64\u6d3b\u8dc3\u7684\u4e34\u5e8a\u73b0\u72b6\u8868\u660e\u66f4\u591a\u7684\u62ef\u6551\u751f\u547d\u7684\u7597\u6cd5\u79bb\u6211\u4eec\u8d8a\u6765\u8d8a\u8fd1\u3002\u5c3d\u7ba1\u5982\u6b64\uff0c\u91cd\u590d\u3001\u4f4e\u6548\u4e14\u843d\u540e\u7684\u4e34\u5e8a\u8bbe\u8ba1\u4e5f\u5e76\u4e0d\u5c11\u89c1\uff0c\u660e\u663e\u4e0b\u964d\u7684\u62db\u52df\u901f\u5ea6\u5c31\u662f\u4e00\u4e2a\u8b66\u793a\u4fe1\u53f7\u3002\u9762\u5bf9\u53d7\u8bd5\u8005\u6570\u91cf\u7684\u9650\u5236\uff0c\u8fd9\u4e2a\u9886\u57df\u9700\u8981\u4f18\u5316\u914d\u7f6e\u8d44\u6e90\u5e76\u4e14\u5c3d\u6700\u5927\u5316\u7684\u52aa\u529b\u6765\u521b\u65b0\u6297PD-1\/PD-L1\u6cbb\u7597\u7684\u4e34\u5e8a\u65b9\u6848\uff0c\u4e0d\u4ec5\u4ec5\u57fa\u4e8e\u5f3a\u5927\u7684\u79d1\u5b66\u8bc1\u636e\uff0c\u66f4\u4e3a\u4e86\u5e2e\u52a9\u60a3\u8005\u672a\u88ab\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\u3002<\/span><\/p>\n<p><br 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!important;\">\u4e13\u6ce8\u516b\u5366\u7684\u5c0f\u548c\u5c1a<\/span><span style=\"max-width: 100%;font-size: 14px;widows: 1;font-family: \u5fae\u8f6f\u96c5\u9ed1;font-style: italic;text-indent: 32px;color: rgb(102, 102, 102);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\uff0c<\/span><span style=\"max-width: 100%;font-size: 14px;widows: 1;font-family: \u5fae\u8f6f\u96c5\u9ed1;font-style: italic;text-indent: 32px;color: rgb(102, 102, 102);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u767b\u8f7d<\/span><span style=\"max-width: 100%;font-size: 14px;widows: 1;font-family: \u5fae\u8f6f\u96c5\u9ed1;font-style: italic;text-indent: 32px;color: rgb(102, 102, 102);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u8be5\u6587\u7ae0\u76ee\u7684\u4e3a\u66f4\u5e7f\u6cdb\u7684\u4f20\u9012\u884c\u4e1a\u4fe1\u606f\uff0c\u4e0d\u4ee3\u8868\u8d5e\u540c\u5176\u89c2\u70b9\u6216\u5bf9\u5176\u771f\u5b9e\u6027\u8d1f\u8d23\u3002\u6587\u7ae0\u7248\u6743\u5f52\u539f\u4f5c\u8005\u53ca\u539f\u51fa\u5904\u6240\u6709\uff0c\u6587\u7ae0\u5185\u5bb9\u4ec5\u4f9b\u53c2\u8003\u3002\u672c\u7f51\u62e5\u6709\u5bf9\u6b64\u58f0\u660e\u7684\u6700\u7ec8\u89e3\u91ca\u6743\uff0c\u82e5\u65e0\u610f\u4fb5\u72af\u7248\u6743\uff0c\u8bf7\u8054\u7cfb\u5c0f\u7f16\u5220\u9664\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section  label=\"Powered by 135editor.com\" style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section  label=\"Powered by 135editor.com\" style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section  label=\"Powered by 135editor.com\" style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section  label=\"Powered by 135editor.com\" style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"margin-right: auto;margin-left: auto;max-width: 100%;width: 333.594px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section  style=\"max-width: 100%;display: inline-block;width: 333.594px;vertical-align: top;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section  style=\"max-width: 100%;display: inline-block;vertical-align: top;width: 133.438px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 0.5em;margin-bottom: 0.5em;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;border-top: 1px dotted rgb(223, 223, 223);overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;display: inline-block;vertical-align: top;width: 50.0312px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 5px;margin-bottom: 10px;max-width: 100%;line-height: 0.8;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;width: 0px;display: inline-block;border-top: 0.8em solid rgb(187, 227, 197);overflow-wrap: break-word !important;border-left: 0.7em solid transparent !important;border-right: 0.7em solid transparent !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;display: inline-block;vertical-align: top;width: 133.438px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 0.5em;margin-bottom: 0.5em;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;border-top: 1px dotted rgb(223, 223, 223);overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-right: 10px;padding-left: 10px;max-width: 100%;box-sizing: border-box;font-size: 14px;letter-spacing: 0px;line-height: 2;color: rgb(160, 160, 160);overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;text-indent: 0em;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(136, 136, 136);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5b66\u5982\u9006\u6c34\u884c\u821f\uff0c\u4e0d\u8fdb\u5219\u9000\uff1b<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-indent: 0em;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(136, 136, 136);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5fc3\u4f3c\u5e73\u539f\u8d70\u9a6c\uff0c\u6613\u653e\u96be\u6536\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section  style=\"max-width: 100%;display: inline-block;vertical-align: top;width: 133.438px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 18px;margin-bottom: 8px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;border-top: 1px dotted rgb(223, 223, 223);overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;display: inline-block;vertical-align: top;width: 50.0312px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;line-height: 0.8;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section   style=\"max-width: 100%;box-sizing: border-box;width: 0px;display: inline-block;border-bottom: 0.8em solid rgb(121, 204, 213);overflow-wrap: break-word !important;border-left: 0.7em solid transparent !important;border-right: 0.7em solid transparent !important;\"><\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;display: inline-block;vertical-align: top;width: 133.438px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 18px;margin-bottom: 8px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;border-top: 1px dotted rgb(223, 223, 223);overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"__bg_gif\"      title=\"CRI+IQVIA\uff1a\u6297PD-1\/PD-L1\u5236\u5242\u76842250\u4e2a\u4e34\u5e8a\u73b0\u72b6\" width=\"auto\"  style=\"display: inline;box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible !important;width: 558px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/0-1544159595.gif\" alt=\"CRI+IQVIA\uff1a\u6297PD-1\/PD-L1\u5236\u5242\u76842250\u4e2a\u4e34\u5e8a\u73b0\u72b6\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<section  label=\"Powered by 135editor.com\" style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section style=\"margin-right: auto;margin-left: auto;padding: 0.5em 0em;max-width: 100%;width: 320px;overflow: hidden;border-radius: 5px;border-width: 1px;border-style: solid;border-color: rgb(200, 200, 200);text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-bottom: 0.5em;max-width: 100%;overflow: hidden;display: inline-block;vertical-align: bottom;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;vertical-align: top;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(136, 136, 136);font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/span><\/p>\n<\/section>\n<section style=\"padding-top: 0.3em;max-width: 100%;border-top: 1px dashed rgb(168, 164, 171);display: inline-block;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(102, 102, 102);font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(136, 136, 136);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u6bcf\u65e5\u66f4\u65b0 \u6b22\u8fce\u8ba2\u9605+<\/span><\/p>\n<section  style=\"max-width: 100%;font-size: 14px;color: rgb(35, 21, 10);display: inline-block;width: 111.297px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word 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