{"id":73598,"date":"2018-11-24T01:00:00","date_gmt":"2018-12-07T05:17:56","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/12\/07\/9bb6066093\/"},"modified":"2018-12-07T13:17:57","modified_gmt":"2018-12-07T05:17:57","slug":"9bb6066093","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/73598\/","title":{"rendered":"\u6700\u65b0\u76d8\u70b9\uff1a\u809d\u764c\u7684\u4e0a\u5e02\u9776\u5411\u836f\u7269\uff08\u4e00\uff09"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"text-align: center;\"><span style=\"color: rgb(51, 51, 51);font-family: -apple-system-font, system-ui, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 14px;letter-spacing: 0.544px;text-align: center;background-color: rgb(255, 255, 255);\">\u70b9\u51fb\u4e0a\u65b9\u7684&nbsp;&nbsp;\u25b2&nbsp;\u6dfb\u52a0\u5173\u6ce8<\/span><\/p>\n<p 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!important;overflow-wrap: break-word !important;\"  \/><\/p>\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-right: auto;margin-left: auto;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 20px;max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section style=\"margin-left: 40px;max-width: 100%;box-sizing: border-box;display: inline-block;color: inherit;overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"margin-top: 0.2em;padding-right: 0.5em;padding-bottom: 5px;padding-left: 1.2em;max-width: 100%;box-sizing: border-box;color: rgb(113, 49, 71);font-size: 18px;line-height: 1;border-bottom: 1px solid rgb(227, 190, 203);border-top-color: rgb(227, 190, 203);border-right-color: rgb(227, 190, 203);border-left-color: rgb(227, 190, 203);overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<section class=\"\"  style=\"margin: 5px 1.2em;max-width: 100%;line-height: 1;color: rgb(113, 49, 71);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;font-size: 15px;white-space: normal;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u809d\u764c\u9776\u5411\u6cbb\u7597\u673a\u5236<\/strong><\/section>\n<\/section>\n<section style=\"margin-top: -48px;padding: 9px;max-width: 100%;box-sizing: border-box;width: 40px;height: 40px;border-radius: 50%;color: rgb(113, 49, 71);background-color: rgb(227, 190, 203);overflow-wrap: break-word !important;\"><\/section>\n<section   style=\"margin-top: -18px;margin-left: 25px;padding: 6px;max-width: 100%;box-sizing: border-box;width: 25px;height: 25px;border-radius: 50%;color: rgb(114, 129, 33);background-color: rgb(221, 227, 190);overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section  class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<section  class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;letter-spacing: 1.5px;text-align: justify;text-indent: 28px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">&nbsp; &nbsp; \u809d\u764c\u9776\u5411\u6cbb\u7597\u7684\u57fa\u7840\u4e3b\u8981\u5305\u62ec\u4fe1\u53f7\u4f20\u5bfc\u9014\u5f84\u548c\u65b0\u751f\u8840\u7ba1\u4e24\u65b9\u9762\u3002<\/span><strong style=\"max-width: 100%;font-size: 15px;letter-spacing: 1.5px;text-align: justify;text-indent: 28px;white-space: normal;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u4e00\u65b9\u9762<\/strong><span style=\"max-width: 100%;font-size: 15px;letter-spacing: 1.5px;text-align: justify;text-indent: 28px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\uff0c\u591a\u6fc0\u9176\u6291\u5236\u5242\u53ef\u4ee5\u901a\u8fc7\u6291\u5236\u8840\u7ba1\u5185\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\uff08VEGFR\uff09\u3001\u8840\u5c0f\u677f\u884d\u751f\u751f\u957f\u56e0\u5b50\u53d7\u4f53\uff08PDGFR\uff09\u7b49\u963b\u65ad\u80bf\u7624\u8840\u7ba1\u751f\u957f\uff1b<\/span><strong style=\"max-width: 100%;font-size: 15px;letter-spacing: 1.5px;text-align: justify;text-indent: 28px;white-space: normal;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u53e6\u4e00\u65b9\u9762<\/strong><span style=\"max-width: 100%;font-size: 15px;letter-spacing: 1.5px;text-align: justify;text-indent: 28px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\uff0c\u53c8\u53ef\u901a\u8fc7\u963b\u65adRaf\/MEK\/ERK\u7b49\u4fe1\u53f7\u4f20\u5bfc\u901a\u8def\u6291\u5236\u80bf\u7624\u7ec6\u80de\u589e\u6b96\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"\"           style=\"box-sizing: border-box !important;overflow-wrap: break-word !important;width: 458px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/6-1544159877.png\" alt=\"\u6700\u65b0\u76d8\u70b9\uff1a\u809d\u764c\u7684\u4e0a\u5e02\u9776\u5411\u836f\u7269\uff08\u4e00\uff09\" title=\"\u6700\u65b0\u76d8\u70b9\uff1a\u809d\u764c\u7684\u4e0a\u5e02\u9776\u5411\u836f\u7269\uff08\u4e00\uff09\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<p style=\"margin-bottom: 8px;max-width: 100%;min-height: 1em;text-align: center;line-height: normal;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5fae\u8f6f\u96c5\u9ed1, sans-serif;letter-spacing: 0.5px;background: white;font-size: 14px;color: rgb(136, 136, 136);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u809d\u764c\u53cc\u91cd\u9776\u5411\u6297\u80bf\u7624\u4f5c\u7528<\/span><\/p>\n<\/section>\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"margin-right: auto;margin-left: auto;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 20px;max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section style=\"margin-left: 40px;max-width: 100%;box-sizing: border-box;display: inline-block;color: inherit;overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"margin-top: 0.2em;padding-right: 0.5em;padding-bottom: 5px;padding-left: 1.2em;max-width: 100%;box-sizing: border-box;color: rgb(113, 49, 71);font-size: 18px;line-height: 1;border-bottom: 1px solid rgb(227, 190, 203);border-top-color: rgb(227, 190, 203);border-right-color: rgb(227, 190, 203);border-left-color: rgb(227, 190, 203);overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<section class=\"\"  style=\"margin: 5px 1.2em;max-width: 100%;line-height: 1;color: rgb(113, 49, 71);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;font-size: 15px;white-space: normal;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u809d\u764c\u5168\u7403\u53ef\u7528\u836f\u7269\u6c47\u603b<\/strong><\/section>\n<\/section>\n<section style=\"margin-top: -48px;padding: 9px;max-width: 100%;box-sizing: border-box;width: 40px;height: 40px;border-radius: 50%;color: rgb(113, 49, 71);background-color: rgb(227, 190, 203);overflow-wrap: break-word !important;\"><\/section>\n<section   style=\"margin-top: -18px;margin-left: 25px;padding: 6px;max-width: 100%;box-sizing: border-box;width: 25px;height: 25px;border-radius: 50%;color: rgb(114, 129, 33);background-color: rgb(221, 227, 190);overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section  class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;display: flex;justify-content: center;align-items: center;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;display: inline-block;vertical-align: top;width: 50px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;text-align: right;font-size: 12.8px;line-height: 1;transform: translate3d(5px, 0px, 0px);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;display: inline-block;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;width: 0.7em;height: 0.7em;display: inline-block;vertical-align: middle;color: rgb(254, 254, 254);background-color: rgb(127, 212, 207);transform: rotate(45deg);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/section>\n<section style=\"margin-left: 0.2em;max-width: 100%;width: 0.4em;height: 0.4em;display: inline-block;vertical-align: middle;color: rgb(254, 254, 254);background-color: rgb(127, 212, 207);transform: rotate(45deg);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"padding-right: 15px;padding-left: 15px;max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: top;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;font-weight: 700;letter-spacing: 2px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u9776\u5411\u6cbb\u7597\u836f\u7269<\/span><\/section>\n<\/section>\n<\/section>\n<section style=\"max-width: 100%;display: inline-block;vertical-align: top;width: 50px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;text-align: left;font-size: 12.8px;line-height: 1;transform: translate3d(-5px, 0px, 0px);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;display: inline-block;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-right: 0.2em;max-width: 100%;width: 0.4em;height: 0.4em;display: inline-block;vertical-align: middle;color: rgb(254, 254, 254);background-color: rgb(127, 212, 207);transform: rotate(45deg);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/section>\n<section style=\"max-width: 100%;width: 0.7em;height: 0.7em;display: inline-block;vertical-align: middle;color: rgb(254, 254, 254);background-color: rgb(127, 212, 207);transform: rotate(45deg);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section  class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section style=\"padding-top: 10px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section  style=\"margin-right: auto;margin-left: auto;max-width: 100%;width: 677px;background: rgb(241, 240, 241);color: rgb(63, 62, 63);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section  style=\"margin-right: auto;margin-left: auto;max-width: 100%;width: 677px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"margin: -10px auto;max-width: 100%;width: 677px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"padding: 20px 10px;max-width: 100%;min-height: 1em;font-size: 15px;letter-spacing: 1.5px;line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 82, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u2756\u4ed1\u4f10\u66ff\u5c3c\uff08\u4e50\u536b\u739b<sup style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u00ae<\/sup>\uff09<\/strong><\/span>\uff1a<strong style=\"max-width: 100%;white-space: normal;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u9776\u70b9PDGFR-\u03b1\u3001VEGFR1\/2\/3\u3001FGFR1\/2\/3\/4\u3001KIT\u3001RET<\/strong>\u30022018\u5e749\u6708\u4e2d\u56fd\u83b7\u6279\u4e0a\u5e02\uff0c\u76ee\u524d\u8fd8\u6ca1\u6709\u7eb3\u5165\u533b\u4fdd\u3002\u4ed1\u4f10\u66ff\u5c3c\u5355\u836f\u5728\u4e2d\u56fd\u7528\u4e8e\u6cbb\u7597\u65e2\u5f80\u672a\u63a5\u53d7\u8fc7\u5168\u8eab\u7cfb\u7edf\u6cbb\u7597\u7684\u4e0d\u53ef\u5207\u9664\u7684\u809d\u764c\u60a3\u8005\uff0c\u662f\u5341\u5e74\u6765\u7b2c\u4e00\u4e2a\u5728\u4e2d\u56fd\u88ab\u6279\u51c6\u4f5c\u4e3a\u809d\u7ec6\u80de\u764c\u4e00\u7ebf\u7cfb\u7edf\u6cbb\u7597\u7684\u65b0\u6cbb\u7597\u65b9\u6848\uff0c<strong style=\"max-width: 100%;white-space: normal;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u4e2d\u4f4d\u603b\u751f\u5b58\u671f\uff1a13.6\u4e2a\u6708\uff1b\u4e2d\u4f4d\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff1a7.3\u4e2a\u6708\uff1b\u5ba2\u89c2\u7f13\u89e3\u7387\uff1a41%<\/strong>\u3002<\/p>\n<p style=\"padding: 20px 10px;max-width: 100%;min-height: 1em;font-size: 15px;letter-spacing: 1.5px;line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;caret-color: red;color: rgb(0, 82, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u2756\u745e\u6208\u975e\u5c3c\uff08\u62dc\u4e07\u6208<\/strong><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;color: rgb(2, 30, 170);font-size: 16px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><sup style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u00ae<\/sup><\/strong><\/strong><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\uff09<\/strong><\/span><span style=\"max-width: 100%;caret-color: red;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\uff1a<\/span><strong style=\"max-width: 100%;caret-color: red;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u9776\u70b9PDGFR-\u03b1\/\u03b2\u3001VEGFR1\/2\/3\u3001KIT\u3001FGFR1\/2\u3001RET\u3001B\/C-Raf<\/strong><span style=\"max-width: 100%;caret-color: red;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u30022017\u5e743\u6708\u4e2d\u56fd\u83b7\u6279\u4e0a\u5e02\uff0c<\/span><span style=\"max-width: 100%;caret-color: red;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u76ee\u524d<strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5df2\u7eb3\u5165\u56fd\u5bb6\u4e59\u7c7b\u533b\u4fdd\u76ee\u5f55<\/strong><\/span><span style=\"max-width: 100%;caret-color: red;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u3002\u745e\u6208\u975e\u5c3c\u7528\u4e8e\u65e2\u5f80\u4f7f\u7528\u8fc7\u7d22\u62c9\u975e\u5c3c\uff08\u591a\u5409\u7f8e\uff09\u6cbb\u7597\u7684\u809d\u7ec6\u80de\u764c(<\/span><span style=\"max-width: 100%;caret-color: red;box-sizing: border-box !important;overflow-wrap: break-word !important;\">HCC<\/span><span style=\"max-width: 100%;caret-color: red;box-sizing: border-box !important;overflow-wrap: break-word !important;\">)\uff0c\u6210\u4e3a\u809d\u764cHCC\u4e8c\u7ebf\u6cbb\u7597\u836f\u7269\uff0c\u8fd9\u4e5f\u662f\u4e2d\u56fd\u9996\u4e2a\u809d\u764c\u4e8c\u7ebf\u9776\u5411\u836f\u3002\u745e\u6208\u975e\u5c3c\u7528\u4e8e\u65e2\u5f80\u4f7f\u7528\u8fc7\u7d22\u62c9\u975e\u5c3c\u7684\u809d\u7ec6\u80de\u764c\uff0c<\/span><strong style=\"max-width: 100%;caret-color: red;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u4e2d\u4f4d\u603b\u751f\u5b58\u671f\uff1a10.6\u4e2a\u6708\uff1b\u4e2d\u4f4d\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff1a3.1-3.4\u4e2a\u6708\uff1b\u603b\u7f13\u89e3\u7387\uff1a7%-11%<\/strong><span style=\"max-width: 100%;caret-color: red;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u3002<\/span><\/p>\n<p style=\"padding: 20px 10px;max-width: 100%;min-height: 1em;font-size: 15px;letter-spacing: 1.5px;line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 82, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u2756\u7d22\u62c9\u975e\u5c3c\uff08\u591a\u5409\u7f8e<strong style=\"max-width: 100%;color: rgb(2, 30, 170);font-size: 16px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><sup style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u00ae<\/sup><\/strong>\uff09<\/strong><\/span>\uff1a<strong style=\"max-width: 100%;white-space: normal;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u9776\u70b9VEGFR1\/2\/3\u3001PDGFR-\u03b2\u3001B-raf\u3001KIT\u3001RET\u3001C-Raf\u3001FLT3<\/strong>\u30022006\u5e749\u6708\u4e2d\u56fd\u83b7\u6279\u4e0a\u5e02\uff0c\u76ee\u524d<strong style=\"max-width: 100%;white-space: normal;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5df2\u7eb3\u5165\u56fd\u5bb6\u4e59\u7c7b\u533b\u4fdd\u76ee\u5f55<\/strong>\u3002\u7d22\u62c9\u975e\u5c3c\u662f\u5168\u7403\u7b2c\u4e00\u4e2a\u6cbb\u7597\u809d\u7ec6\u80de\u764c\u7684\u9776\u5411\u836f\u7269\uff0c<strong style=\"max-width: 100%;white-space: normal;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u4e2d\u4f4d\u603b\u751f\u5b58\u671f\uff1a10.7\u4e2a\u6708\uff1b\u4e2d\u4f4d\u75be\u75c5\u8fdb\u5c55\u65f6\u95f4\uff1a5.5\u4e2a\u6708<\/strong>\u3002<\/p>\n<p style=\"padding: 20px 10px;max-width: 100%;min-height: 1em;font-size: 15px;letter-spacing: 1.5px;line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 82, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u2756\u5361\u535a\u66ff\u5c3c\uff08Cabometyx<sup style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u00ae<\/sup>\uff09<\/strong><\/span>\uff1a<strong style=\"max-width: 100%;white-space: normal;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u9776\u70b9VEGFR1\/2\/3\uff0cTYRO3\uff0cROS\uff0cUFO\uff0cTIE2\uff0cc-Met\/HGFR\uff0cKIT\uff0cNTRK2\uff0cRET<\/strong>\u30022012\u5e7411\u6708\u7f8e\u56fd\u9996\u6279\uff0c\u4e2d\u56fd\u8fd8\u672a\u83b7\u6279\u4e0a\u5e02\uff0c\u76ee\u524d\u56fd\u5185\u6709\u4eff\u5236\u836f\u5728\u7814\u3002\u5361\u535a\u66ff\u5c3c\u7528\u4e8e\u665a\u671f\u809d\u764c\u7684\u4e8c\u7ebf\u6cbb\u7597\uff0c\u7ecf\u8fc7\u7d22\u62c9\u975e\u5c3c\u6cbb\u7597\u540e\u8fdb\u5c55\u7684\u665a\u671f\u809d\u7ec6\u80de\u764c\u60a3\u8005\uff0c\u63a5\u53d7\u5361\u535a\u66ff\u5c3c\u8f83\u5b89\u6170\u5242\u663e\u8457\u6539\u5584\u603b\u751f\u5b58\u671f\uff0c\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\u548c\u5ba2\u89c2\u7f13\u89e3\u7387\u4e5f\u6709\u660e\u663e\u6539\u5584\uff0c<strong style=\"max-width: 100%;white-space: normal;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u4e2d\u4f4d\u603b\u751f\u5b58\u671f\uff1a11.3\u4e2a\u6708\uff1b\u4e2d\u4f4d\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff1a5.5\u4e2a\u6708\uff1b\u5ba2\u89c2\u7f13\u89e3\u7387\uff1a4%\uff1b\u75be\u75c5\u63a7\u5236\u7387\uff1a64%&nbsp;<\/strong>\u3002<\/p>\n<\/section>\n<section  style=\"margin-top: 10px;max-width: 100%;width: 677px;justify-content: flex-end;display: flex;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section    style=\"margin-right: 10px;max-width: 100%;width: 10px;height: 10px;background: rgb(187, 188, 187);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section  class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;display: flex;justify-content: center;align-items: center;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;display: inline-block;vertical-align: top;width: 50px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;text-align: right;font-size: 12.8px;line-height: 1;transform: translate3d(5px, 0px, 0px);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;display: inline-block;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;width: 0.7em;height: 0.7em;display: inline-block;vertical-align: middle;color: rgb(254, 254, 254);background-color: rgb(127, 212, 207);transform: rotate(45deg);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/section>\n<section style=\"margin-left: 0.2em;max-width: 100%;width: 0.4em;height: 0.4em;display: inline-block;vertical-align: middle;color: rgb(254, 254, 254);background-color: rgb(127, 212, 207);transform: rotate(45deg);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"padding-right: 15px;padding-left: 15px;max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: top;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 15px;font-weight: 700;letter-spacing: 2px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">PD-1<\/span><\/section>\n<\/section>\n<\/section>\n<section style=\"max-width: 100%;display: inline-block;vertical-align: top;width: 50px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;text-align: left;font-size: 12.8px;line-height: 1;transform: translate3d(-5px, 0px, 0px);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;display: inline-block;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-right: 0.2em;max-width: 100%;width: 0.4em;height: 0.4em;display: inline-block;vertical-align: middle;color: rgb(254, 254, 254);background-color: rgb(127, 212, 207);transform: rotate(45deg);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/section>\n<section style=\"max-width: 100%;width: 0.7em;height: 0.7em;display: inline-block;vertical-align: middle;color: rgb(254, 254, 254);background-color: rgb(127, 212, 207);transform: rotate(45deg);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section  class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section style=\"padding-top: 10px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section  style=\"margin-right: auto;margin-left: auto;max-width: 100%;width: 677px;background: rgb(241, 240, 241);color: rgb(63, 62, 63);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section  style=\"margin-right: auto;margin-left: auto;max-width: 100%;width: 677px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"margin: -10px auto;max-width: 100%;letter-spacing: 0.544px;text-align: justify;white-space: normal;width: 677px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"padding: 20px 10px;max-width: 100%;min-height: 1em;text-align: left;font-size: 15px;letter-spacing: 1.5px;line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 82, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u2756\u5e15\u535a\u5229\u73e0\u5355\u6297\uff08\u53ef\u745e\u8fbe<strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><sup style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u00ae<\/sup><\/strong><\/strong>\uff09<\/strong><\/span>\uff1a2014\u5e749\u6708\u7f8e\u56fd\u9996\u6279\uff0c\u5e15\u535a\u5229\u73e0\u5355\u6297\u5df2\u572880\u591a\u4e2a\u56fd\u5bb6\u83b7\u6279\u4f7f\u7528\uff0c\u8986\u76d6\u4e86\u5305\u62ec<strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u809d\u764c\u7b4910\u4e2a\u764c\u79cd\u768414\u4e2a\u9002\u5e94\u75c7<\/strong>\u30022018\u5e747\u6708\u4e2d\u56fd\u4e0a\u5e02\uff0c\u53ea\u83b7\u6279\u4e86\u7528\u4e8e\u4e00\u7ebf\u6cbb\u7597\u5931\u8d25\u7684\u4e0d\u53ef\u5207\u9664\u6216\u8f6c\u79fb\u6027\u9ed1\u8272\u7d20\u7624\uff0c\u76ee\u524d\u8fd8\u6ca1\u6709\u7eb3\u5165\u533b\u4fdd\uff0c\u4f46\u6709\u4e70\u836f\u8d60\u836f\u53ca\u4f4e\u4fdd\u4f18\u60e0\u653f\u7b56\u3002\u5e15\u535a\u5229\u73e0\u5355\u6297\uff08K\u836f\uff09\u7684Keynote-224\u7814\u7a76\u4e8c\u7ebf\u6cbb\u7597\u809d\u764c\u83b7\u5f97\u4e86\u9633\u6027\u7ed3\u679c\uff0c<strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5ba2\u89c2\u7f13\u89e3\u7387\uff1a17%<\/strong>\u3002<\/p>\n<p style=\"padding: 20px 10px;max-width: 100%;min-height: 1em;text-align: left;font-size: 15px;letter-spacing: 1.5px;line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 82, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u2756\u7eb3\u6b66\u5229\u5c24\u5355\u6297\uff08<strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u6b27\u72c4\u6c83<sup style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u00ae<\/sup><\/strong>\uff09<\/strong><\/span>\uff1a2014\u5e747\u6708\u65e5\u672c\u9996\u6279\uff0c\u7eb3\u6b66\u5229\u5c24\u5355\u6297\u5df2\u5728\u5168\u7403\u8d85\u8fc765\u4e2a\u56fd\u5bb6\u53ca\u5730\u533a<strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u83b7\u6279\u4e86\u5305\u62ec\u809d\u764c\u5728\u5185\u76849\u4e2a\u7624\u79cd\u768417\u9879\u9002\u5e94\u75c7<\/strong>\u30022018\u5e746\u6708\u4e2d\u56fd\u83b7\u6279\u4e0a\u5e02\uff0c\u7528\u4e8e\u6cbb\u7597\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff0c\u76ee\u524d\u8fd8\u6ca1\u6709\u7eb3\u5165\u533b\u4fdd\u3002\u7eb3\u6b66\u5229\u5c24\u5355\u6297\u5bf9\u809d\u764c\u60a3\u8005\u5177\u6709\u597d\u7684\u7597\u6548\u548c\u826f\u597d\u7684\u5b89\u5168\u6027\uff0c<strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u603b\u7f13\u89e3\u7387\uff1a23%<\/strong>\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p><br  \/><\/p>\n<p style=\"margin-bottom: 20px;max-width: 100%;min-height: 1em;letter-spacing: 0.544px;line-height: 2em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;widows: 1;font-family: \u5fae\u8f6f\u96c5\u9ed1;font-style: italic;text-indent: 32px;color: rgb(102, 102, 102);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u6587<\/span><span style=\"max-width: 100%;font-size: 14px;widows: 1;font-family: \u5fae\u8f6f\u96c5\u9ed1;font-style: italic;text-indent: 32px;color: rgb(102, 102, 102);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u7ae0\u4fe1\u606f<\/span><span style=\"max-width: 100%;font-size: 14px;widows: 1;font-family: \u5fae\u8f6f\u96c5\u9ed1;font-style: italic;text-indent: 32px;color: rgb(102, 102, 102);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u6e90\u4e8e\u516c\u4f17\u53f7&nbsp;\uff0c<\/span><span style=\"max-width: 100%;font-size: 14px;widows: 1;font-family: \u5fae\u8f6f\u96c5\u9ed1;font-style: italic;text-indent: 32px;color: rgb(102, 102, 102);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u767b\u8f7d\u8be5\u6587\u7ae0\u76ee\u7684\u4e3a\u66f4\u5e7f\u6cdb\u7684\u4f20\u9012\u884c\u4e1a\u4fe1\u606f\uff0c\u4e0d\u4ee3\u8868\u8d5e\u540c\u5176\u89c2\u70b9\u6216\u5bf9\u5176\u771f\u5b9e\u6027\u8d1f\u8d23\u3002\u6587\u7ae0\u7248\u6743\u5f52\u539f\u4f5c\u8005\u53ca\u539f\u51fa\u5904\u6240\u6709\uff0c\u6587\u7ae0\u5185\u5bb9\u4ec5\u4f9b\u53c2\u8003\u3002\u672c\u7f51\u62e5\u6709\u5bf9\u6b64\u58f0\u660e\u7684\u6700\u7ec8\u89e3\u91ca\u6743\uff0c\u82e5\u65e0\u610f\u4fb5\u72af\u7248\u6743\uff0c\u8bf7\u8054\u7cfb\u5c0f\u7f16\u5220\u9664\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box 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100%;display: inline-block;vertical-align: top;width: 50.0312px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;line-height: 0.8;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section   style=\"max-width: 100%;box-sizing: border-box;width: 0px;display: inline-block;border-bottom: 0.8em solid rgb(121, 204, 213);overflow-wrap: break-word !important;border-left: 0.7em solid transparent !important;border-right: 0.7em solid transparent !important;\"><\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;display: inline-block;vertical-align: top;width: 133.438px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 18px;margin-bottom: 8px;max-width: 100%;box-sizing: border-box 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!important;\"><\/span><\/p>\n<\/section>\n<section style=\"padding-top: 0.3em;max-width: 100%;border-top: 1px dashed rgb(168, 164, 171);display: inline-block;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(102, 102, 102);font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(136, 136, 136);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u6bcf\u65e5\u66f4\u65b0 \u6b22\u8fce\u8ba2\u9605+<\/span><\/p>\n<section  style=\"max-width: 100%;font-size: 14px;color: rgb(35, 21, 10);display: inline-block;width: 111.297px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  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