{"id":73616,"date":"2018-11-23T01:00:00","date_gmt":"2018-12-07T05:18:12","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/12\/07\/47ad0b27d4\/"},"modified":"2018-12-07T13:18:14","modified_gmt":"2018-12-07T05:18:14","slug":"47ad0b27d4","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/73616\/","title":{"rendered":"\u53f0\u6e7e\u6d69\u9f0e\u6536\u83b7FDA\u7b2c3\u9879\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a\uff1aOBI-888\u7528\u4e8e\u6cbb\u7597\u80f0\u817a\u764c"},"content":{"rendered":"
\n

\u70b9\u51fb\u4e0a\u65b9\u7684  \u25b2 \u6dfb\u52a0\u5173\u6ce8<\/span><\/p>\n


<\/p>\n

11\u670821\u65e5\uff0c\u53f0\u6e7e\u6d69\u9f0e\u751f\u6280\uff08OBI Pharma<\/span>\uff09\u5ba3\u5e03FDA\u6388\u4e88OBI-888\u6cbb\u7597\u80f0\u817a\u764c\u5b64\u513f\u836f\u8d44\u683c\u3002OBI-888\u662ffirst in class \u7684\u9776\u5411\u80bf\u7624\u7ec6\u80de\u8868\u9762\u591a\u7cd6\u4f53\u6297\u539fGlobo H\u7684\u88ab\u52a8\u514d\u75ab\u7597\u6cbb\u7597\u5355\u6297\u836f\u7269\uff0c\u5176\u4f5c\u7528\u673a\u5236\u662f\u6297\u4f53\u4f9d\u8d56\u6027\u7684\u7ec6\u80de\u6bd2\u4f5c\u7528\u3001\u6297\u4f53\u4f9d\u8d56\u6027\u7684\u5de8\u566c\u7ec6\u80de\u541e\u566c\u4f5c\u7528\uff0c\u4ee5\u53ca\u8865\u4f53\u4f9d\u8d56\u6027\u7684\u7ec6\u80de\u6bd2\u6027\u4f5c\u7528\u3002OBI-888<\/span><\/span><\/span><\/span><\/span>\u540c\u65f6\u4e5f\u6709\u6297\u514d\u75ab\u6291\u5236\u548c\u6297\u8840\u7ba1\u751f\u6210\u7684\u4f5c\u7528\u3002<\/span><\/p>\n


<\/p>\n

\"\u53f0\u6e7e\u6d69\u9f0e\u6536\u83b7FDA\u7b2c3\u9879\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a\uff1aOBI-888\u7528\u4e8e\u6cbb\u7597\u80f0\u817a\u764c\"<\/p>\n

\u6765\u6e90\uff1a\u53f0\u6e7e\u6d69\u9f0e\u5b98\u7f51<\/span><\/p>\n


<\/span><\/p>\n

1\u670817\u65e5\uff0cOBI-888<\/span>\u83b7\u5f97FDA\u7684I\u671f\u4e34\u5e8a\u8bb8\u53ef\uff0c\u76ee\u524d\u6b63\u5728\u7f8e\u56fd\u5fb7\u514b\u8428\u65af\u5927\u5b66\u5b89\u5fb7\u68ee\u764c\u75c7\u4e2d\u5fc3\u5f00\u5c55I\u671f\u8bd5\u9a8c\uff0c\u5165\u7ec4\u5c40\u90e8\u79fb\u8f6c\u7684\u5b9e\u4f53\u7624\u60a3\u8005\uff0c\u5305\u62ec\u80f0\u817a\u764c\u3001\u4e73\u817a\u764c\u3001\u80c3\u764c\u3001\u98df\u9053\u764c\u3001\u7ed3\u76f4\u80a0\u764c\u53ca\u80ba\u764c\u7b49\u3002<\/span><\/p>\n


<\/p>\n

\u80f0\u817a\u764c\u8d77\u6e90\u4e8e\u5916\u5206\u6ccc\u6216\u5185\u5206\u6ccc\u80f0\u817a\u7ec6\u80de\uff0c\u662f\u4e00\u79cd\u81f4\u547d\u6027\u75be\u75c5\u3002\u7531\u4e8e\u80f0\u817a<\/span>\u764c\u7684\u6cbb\u7597\u9009\u62e9\u6709\u9650\uff0c\u4ec5\u80fd\u65e9\u671f\u53d1\u73b0\u5e76\u624b\u672f\u5207\u9664\uff0c\u7eb5\u4f7f\u5982\u6b64\uff0c\u8fd9\u4e9b\u60a3\u8005\u76845\u5e74\u5b58\u6d3b\u7387\u53ef\u80fd\u4e5f\u53ea\u670934.3\uff05\u3002\u7531\u4e8e\u80f0\u810f\u764c\u65e9\u671f\u5e76\u65e0\u75c7\u72b6\uff0c\u591a\u6570\u60a3\u8005\u5230\u4e86\u75be\u75c5\u665a\u671f\u624d\u88ab\u8bca\u65ad\u51fa\u6765\u6216\u906d\u8bef\u8bca\uff0c\u8fd9\u65f6\u5bfb\u6c42\u624b\u672f\u6cbb\u7597\u901a\u5e38\u4e3a\u65f6\u5df2\u665a\uff0c5\u5e74\u5b58\u6d3b\u7387\u4ec58.5\uff05\u3002<\/span><\/span><\/p>\n


<\/span>\u53f0\u6e7e\u6d69\u9f0e\u603b\u7ecf\u7406\u9ec4\u79c0\u7f8e\u8868\u793a\uff1a\u201cOBI-888\u83b7\u5f97FDA\u6388\u4e88\u7684\u80f0\u817a\u764c\u5b64\u513f\u836f\u8d44\u683c\u662fGlobo H\u5355\u6297\u65b0\u836f\u5f00\u53d1\u7684\u91cc\u7a0b\u7891\u3002\u76ee\u524d\u80f0\u817a\u764c\u7684\u6cbb\u7597\u9009\u62e9\u975e\u5e38\u6709\u9650\uff0c\u53f0\u6e7e\u6d69\u9f0e\u4e13\u6ce8\u4e8e\u5f00\u53d1\u9488\u5bf9\u672a\u88ab\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\u7684\u7597\u6cd5\uff0c\u5c06\u5c3d\u6700\u5927\u52aa\u529b\uff0c\u5728\u534f\u52a9\u4eba\u4eec\u6297\u764c\u4e4b\u5916\uff0c\u4e5f\u517c\u987e\u751f\u6d3b\u54c1\u8d28\u3002\u201d<\/span><\/p>\n


<\/span><\/p>\n

\u8fd9\u4e5f\u662f\u53f0\u6e7e\u6d69\u9f0e\u4eceFDA\u83b7\u5f97\u7684\u7b2c3\u9879\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a\u3002\u4eca\u5e747\u6708\u548c9\u6708\uff0c<\/span>DNA\u70f7\u57fa\u5316\u5242\u7c7b\u836f\u7269OBI-34<\/span>24(TH-3424<\/span><\/span>)\u5148\u540e\u88abFDA\u6388\u4e88\u4e86\u6cbb\u7597\u809d\u7ec6\u80de\u764c\u548c\u6025\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u7684\u5b64\u513f\u836f\u8d44\u683c\u3002OBI-3424\u662f\u4e00\u5316\u7597\u524d\u9a71\u578b\u65b0\u836f\uff0c\u4f1a\u9009\u62e9\u6027\u5730\u5728AKR1C3\u9175\u7d20\u4f5c\u7528\u4e0b\u91ca\u51fa\u5f3a\u6548DNA\u70f7\u57fa\u5316\u5242\uff08\u7279\u522b\u9002\u7528\u4e8eAKR1C3\u9ad8\u8868\u8fbe\u7684\u80bf\u7624\uff09<\/span>\uff0c\u662f\u53f0\u6e7e\u6d69\u9f0e\u4e8e2017\u5e746\u6708\u4ece\u7f8e<\/span>\u56fdThreshold Pharmaceuticals\u516c\u53f8\u4e00\u6b21\u6027\u4ed8\u6b3e\u6536\u8d2d\u800c\u6765\u3002<\/span><\/p>\n


<\/span><\/p>\n

\u53f0\u6e7e\u6d69\u9f0e\u6210\u7acb\u4e8e2002\u5e74\uff0c\u4e13\u6ce8\u5f00\u53d1\u521b\u65b0\u6027\u7684\u764c\u75c7\u7597\u6cd5\u3002\u76ee\u524d\u4ea7\u54c1\u7ba1\u7ebf\u4e2d\u5f00\u53d1\u8fdb\u5ea6\u6700\u5feb\u7684\u662f\u7528\u4e8e\u6cbb\u7597\u4e73\u817a\u764c\u7684\u4e3b\u52a8\u514d\u75ab\u7597\u6cd5<\/span><\/span>Adagloxad simolenin\uff08OBI-822\uff09\uff0c\u76ee\u524d\u5904\u4e8eIII\u671f\u9636\u6bb5\u3002<\/span><\/p>\n


<\/p>\n

\u6587<\/span>\u7ae0\u4fe1\u606f\u6e90\u4e8e<\/span>\u516c\u4f17\u53f7\u533b\u836f\u9b54\u65b9\uff0c<\/span>\u767b\u8f7d\u8be5\u6587\u7ae0\u76ee\u7684\u4e3a\u66f4\u5e7f\u6cdb\u7684\u4f20\u9012\u884c\u4e1a\u4fe1\u606f\uff0c\u4e0d\u4ee3\u8868\u8d5e\u540c\u5176\u89c2\u70b9\u6216\u5bf9\u5176\u771f\u5b9e\u6027\u8d1f\u8d23\u3002\u6587\u7ae0\u7248\u6743\u5f52\u539f\u4f5c\u8005\u53ca\u539f\u51fa\u5904\u6240\u6709\uff0c\u6587\u7ae0\u5185\u5bb9\u4ec5\u4f9b\u53c2\u8003\u3002\u672c\u7f51\u62e5\u6709\u5bf9\u6b64\u58f0\u660e\u7684\u6700\u7ec8\u89e3\u91ca\u6743\uff0c\u82e5\u65e0\u610f\u4fb5\u72af\u7248\u6743\uff0c\u8bf7\u8054\u7cfb\u5c0f\u7f16\u5220\u9664\u3002<\/span><\/p>\n


<\/p>\n


<\/p>\n


<\/p>\n

\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n

\u5b66\u5982\u9006\u6c34\u884c\u821f\uff0c\u4e0d\u8fdb\u5219\u9000\uff1b<\/span><\/p>\n

\u5fc3\u4f3c\u5e73\u539f\u8d70\u9a6c\uff0c\u6613\u653e\u96be\u6536\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

\n
\n
\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n<\/section>\n
\n
\n
<\/section>\n<\/section>\n<\/section>\n
\n
\n
\n

<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


<\/p>\n

\"\u53f0\u6e7e\u6d69\u9f0e\u6536\u83b7FDA\u7b2c3\u9879\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a\uff1aOBI-888\u7528\u4e8e\u6cbb\u7597\u80f0\u817a\u764c\"<\/p>\n


<\/p>\n


<\/p>\n

\n
\n
\n
\n
\n

<\/span><\/p>\n<\/section>\n

\n

\u6bcf\u65e5\u66f4\u65b0 \u6b22\u8fce\u8ba2\u9605+<\/span><\/p>\n

\n


<\/p>\n

\n<\/section>\n


<\/p>\n

\u533b\u836f\u5927\u6570\u636e|\u884c\u4e1a\u52a8\u6001|\u653f\u7b56\u89e3\u8bfb<\/span><\/p>\n


<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section><\/div>\n","protected":false},"excerpt":{"rendered":"

\u70b9\u51fb\u4e0a\u65b9\u7684  \u25b2 \u6dfb\u52a0\u5173\u6ce8 11\u670821\u65e5\uff0c\u53f0\u6e7e\u6d69\u9f0e\u751f\u6280\uff08OBI Pharma\uff09\u5ba3 […]<\/p>\n","protected":false},"author":1,"featured_media":73617,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/73616"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=73616"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/73616\/revisions"}],"predecessor-version":[{"id":73620,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/73616\/revisions\/73620"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/73617"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=73616"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=73616"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=73616"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}