{"id":73812,"date":"2018-11-18T01:00:00","date_gmt":"2018-12-07T05:19:45","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/12\/07\/2fd64639c0\/"},"modified":"2018-12-07T13:19:46","modified_gmt":"2018-12-07T05:19:46","slug":"2fd64639c0","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/73812\/","title":{"rendered":"\u4e00\u5468\u836f\u95fb\u4e28\u8bfa\u534e\u5fc3\u529b\u8870\u7aed\u65b0\u836fEntresto\u4e34\u5e8a\u7ed3\u679c\u79ef\u6781 \u4ee5\u5cad\u836f\u4e1a\u53c8\u4e00\u6297\u764c\u836f\u83b7\u6279"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"text-align: center;\"><span style=\"max-width: 100%;color: rgb(51, 51, 51);font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;font-size: 14px;letter-spacing: 0.544px;text-align: center;widows: 1;background-color: rgb(255, 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middle;display: inline-block;width: 57.9219px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"\"     style=\"vertical-align: middle;box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible !important;width: 57.9219px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/3-1544159986.png\" alt=\"\u4e00\u5468\u836f\u95fb\u4e28\u8bfa\u534e\u5fc3\u529b\u8870\u7aed\u65b0\u836fEntresto\u4e34\u5e8a\u7ed3\u679c\u79ef\u6781 \u4ee5\u5cad\u836f\u4e1a\u53c8\u4e00\u6297\u764c\u836f\u83b7\u6279\" title=\"\u4e00\u5468\u836f\u95fb\u4e28\u8bfa\u534e\u5fc3\u529b\u8870\u7aed\u65b0\u836fEntresto\u4e34\u5e8a\u7ed3\u679c\u79ef\u6781 \u4ee5\u5cad\u836f\u4e1a\u53c8\u4e00\u6297\u764c\u836f\u83b7\u6279\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: 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!important;\">1\u3001\u8bfa\u534e\u5ba3\u5e03\u5176Entresto\u7247\u5242\u5728\u5177\u6709\u91cc\u7a0b\u7891\u610f\u4e49\u7684PIONEER-HF\u8bd5\u9a8c\u4e2d\uff0c\u4e0e\u5fc3\u8870\u5e38\u7528\u836f\u7269\u4f9d\u90a3\u666e\u5229\u76f8\u6bd4\uff0c\u53d6\u5f97\u4ee4\u4eba\u77a9\u76ee\u7684\u3001\u4f18\u8d8a\u7684\u4e34\u5e8a\u76ca\u5904\u3002Entresto\u5728\u4f4f\u9662\u521d\u59cb\u65bd\u7528\uff0c\u7528\u4e8e\u6cbb\u7597\u56e0\u6025\u6027\u5931\u4ee3\u507f\u6027\u5fc3\u529b\u8870\u7aed\u4e8b\u4ef6\u800c\u5165\u9662\u6cbb\u7597\u7684\u5c04\u8840\u5206\u6570\u964d\u4f4e\u7684\u5fc3\u529b\u8870\u7aed\u60a3\u8005\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">2\u3001\u9ed8\u6c99\u4e1c\u8fd1\u65e5\u5ba3\u5e03\uff0c\u8bc4\u4f30PD-1\u80bf\u7624\u514d\u75ab\u7597\u6cd5Keytruda\u6cbb\u7597\u665a\u671f\u6216\u8f6c\u79fb\u6027\u98df\u7ba1\u6216\u98df\u7ba1\u80c3\u4ea4\u754c\u90e8\u764c\u7684\u5173\u952e\u6027III\u671f\u4e34\u5e8a\u7814\u7a76KEYNOTE-181\u8fbe\u5230\u4e86\u7814\u7a76\u7684\u4e3b\u8981\u7ec8\u70b9\uff1b<span style=\"max-width: 100%;letter-spacing: 0px;caret-color: red;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u9ed8\u6c99\u4e1c\u8fd1\u65e5\u516c\u5e03\u4e86\u5b9e\u9a8c\u6027\u6297LAG-3\u7597\u6cd5\u548c\u5b9e\u9a8c\u6027\u6297TIGIT\u7597\u6cd5\u7684I\/II\u671f\u5242\u91cf\u53d1\u73b0\u7814\u7a76\u7684\u521d\u6b65\u5b89\u5168\u6027\u548c\u7597\u6548\u6570\u636e\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;letter-spacing: 0px;caret-color: red;box-sizing: border-box !important;overflow-wrap: break-word !important;\">3\u3001\u8d5b\u8bfa\u83f2\u4e0e\u518d\u751f\u5143\u8fd1\u65e5\u5ba3\u5e03\uff0c\u8bc4\u4f30PCSK9\u6291\u5236\u5242\u7c7b\u964d\u8102\u836fPraluent\u5fc3\u8840\u7ba1\u9884\u540e\u7684\u5927\u89c4\u6a21\u4e34\u5e8a\u7814\u7a76ODYSSEY OUTCOMES\u7684\u7ed3\u679c\u3002\u6570\u636e\u663e\u793a\uff0c\u5728\u77ed\u671f\u5185\u53d1\u751f\u4e86\u4e00\u6b21\u6025\u6027\u51a0\u72b6\u52a8\u8109\u7efc\u5408\u5f81\u4e8b\u4ef6\u7684\u60a3\u8005\u4e2d\uff0cPraluent\u6ce8\u5c04\u6db2\u663e\u8457\u964d\u4f4e\u4e86\u4e3b\u8981\u4e0d\u826f\u5fc3\u8840\u7ba1\u4e8b\u4ef6\u7684\u98ce\u9669\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">4\u3001\u536b\u6750\u4e2d\u56fd\u5b50\u516c\u53f8\u536b\u6750\uff08\u4e2d\u56fd\uff09\u836f\u4e1a\u6709\u9650\u516c\u53f8\u8fd1\u65e5\u5ba3\u5e03\u5728\u4e2d\u56fd\u5e02\u573a\u63a8\u51fa\u9776\u5411\u6297\u764c\u836fLenvima\u3002\u4eca\u5e743\u6708\uff0c\u536b\u6750\u4e0e\u9ed8\u6c99\u4e1c\u8fbe\u6210\u5168\u7403\u6218\u7565\u5408\u4f5c\uff0c\u5171\u540c\u5f00\u53d1\u548c\u5546\u4e1a\u5316Lenvima\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word 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!important;\">6\u3001\u827e\u4f2f\u7ef4\u8fd1\u65e5\u516c\u5e03\u4e86\u6cdb\u57fa\u56e0\u578b\u4e19\u809d\u836f\u7269Mavyret\u6cbb\u7597\u521d\u6cbb\u4e14\u4f34\u6709\u4ee3\u507f\u6027\u809d\u786c\u5316\u4e19\u809d\u60a3\u8005\u7684IIIb\u671f\u4e34\u5e8a\u7814\u7a76EXPEDITION-8\u7684\u65b0\u6570\u636e\u3002\u6570\u636e\u663e\u793a\uff0cMavyret 8\u5468\u65b9\u6848\u6cbb\u7597\u57fa\u56e0\u578b1\u30012\u30014\u30015\u30016\u4e19\u809d\u60a3\u8005\u7684\u75c5\u6bd2\u5b66\u6cbb\u6108\u7387\u8fbe100%\uff1b<span style=\"max-width: 100%;letter-spacing: 0px;caret-color: red;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u827e\u4f2f\u7ef4\u548cMission Therapeutics\u5171\u540c\u5ba3\u5e03\u53cc\u65b9\u8fbe\u6210\u7814\u53d1\u5408\u4f5c\u534f\u8bae\uff0c\u5c06\u5229\u7528Mission\u516c\u53f8\u7684\u7279\u5f02\u6027\u9776\u5411\u53bb\u6cdb\u7d20\u5316\u9176\u6cbb\u7597\u963f\u5179\u6d77\u9ed8\u75c5\u548c\u5e15\u91d1\u68ee\u75c5\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">7\u3001\u5409\u5229\u5fb7\u8fd1\u65e5\u516c\u5e03\u4e86\u809d\u75c5\u65b0\u836fGS-9674\u6cbb\u7597\u539f\u53d1\u6027\u786c\u5316\u6027\u80c6\u7ba1\u708e\u7684II\u671f\u4e34\u5e8a\u6570\u636e\u3002GS-9674\u662f\u4e00\u79cd\u9009\u62e9\u6027\u975e\u753e\u4f53\u6cd5\u5c3c\u916fX\u53d7\u4f53\u6fc0\u52a8\u5242\uff0c\u6570\u636e\u663e\u793a\uff0c\u8be5\u836f\u663e\u8457\u6539\u5584\u4e86\u60a3\u8005\u7684\u809d\u810f\u751f\u5316\u548c\u80c6\u6c41\u6de4\u79ef\u7684\u6807\u5fd7\u7269\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">8\u3001\u963f\u65af\u5229\u5eb7\u516c\u5e03\u4e86SGLT2\u6291\u5236\u5242\u7c7b\u964d\u7cd6\u836fdapagliflozin\u91cc\u7a0b\u7891\u5fc3\u8840\u7ba1\u9884\u540e\u7814\u7a76DECLARE-TIMI 58\u7684\u5b8c\u6574\u79ef\u6781\u6570\u636e\u3002\u7ed3\u679c\u663e\u793a\uff0c\u4e0e\u5b89\u6170\u5242\u76f8\u6bd4\uff0cdapagliflozin\u5c06\u5fc3\u8870\u4f4f\u9662\u6216\u5fc3\u8840\u7ba1\u6b7b\u4ea1\u590d\u5408\u98ce\u9669\u663e\u8457\u964d\u4f4e\u4e8617%\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">9\u3001\u963f\u65af\u5229\u5eb7\u8fd1\u65e5\u5bf9\u7814\u53d1\u7ba1\u7ebf\u8fdb\u884c\u4e86\u66f4\u65b0\u3002\u66f4\u65b0\u540e\u7684\u7ba1\u7ebf\u663e\u793a\u5176\u5df2\u7ec8\u6b62\u4e86vistusertib\u4f5c\u4e3a\u5355\u836f\u7597\u6cd5\u6cbb\u7597\u5b9e\u4f53\u80bf\u7624\u4ee5\u53ca\u4e0e\u8be5\u516c\u53f8\u6700\u8fd1\u6279\u51c6\u7684BTK\u6291\u5236\u5242Calquence\u8054\u5408\u7528\u836f\u6cbb\u7597\u8840\u6db2\u764c\u75c7\u7684\u6240\u6709\u7814\u7a76\u3002\u9664\u4e86vistusertib\u4e4b\u5916\uff0c\u8be5\u516c\u53f8\u4e5f\u5df2\u7ec8\u6b62\u4e86\u547c\u5438\u7ec4\u5408\u7597\u6cd5AZD7594\/abediterol\u6cbb\u7597\u54ee\u5598\u548c\u6162\u6027\u963b\u585e\u6027\u80ba\u75c5\u7684\u4e34\u5e8a\u9879\u76ee\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">10\u3001\u4fe1\u8fbe\u751f\u7269\u5236\u836f\u516c\u5e03\u4e86\u4fe1\u8fea\u5229\u5355\u6297\u4e0e\u5409\u897f\u4ed6\u6ee8\u548c\u987a\u94c2\u7684\u7ec4\u5408\u7597\u6cd5\uff0c\u7528\u4e8e\u4e00\u7ebf\u6cbb\u7597\u9cde\u72b6\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7684\u4e00\u98791b\u671f\u961f\u5217E\u7684\u7814\u7a76\u7ed3\u679c\u3002\u8be5\u7ec4\u5408\u7597\u6cd5\u663e\u793a\u51fa\u4e86\u4f18\u5f02\u7684\u6297\u80bf\u7624\u6d3b\u6027\u548c\u4ee4\u4eba\u6ee1\u610f\u7684\u5b89\u5168\u6027\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">11\u3001\u5317\u6d77\u5eb7\u6210\u8fd1\u65e5\u9996\u4e2a\u4ea7\u54c1\u5eb7\u666e\u8212\u2122\u6b63\u5f0f\u5728\u4e2d\u56fd\u4e0a\u5e02\u3002\u5eb7\u666e\u8212\u662f\u4e00\u79cd\u8d85\u9971\u548c\u9499\u78f7\u53e3\u8154\u542b\u6f31\u6db2\uff0c\u53ef\u6709\u6548\u9884\u9632\u548c\u6cbb\u7597\u653e\u7597\u6216\u9ad8\u5242\u91cf\u5316\u7597\u5f15\u8d77\u7684\u53e3\u8154\u9ecf\u819c\u708e\u3002\u4e34\u5e8a\u6570\u636e\u663e\u793a\uff0c\u653e\u7597\u8054\u5408\u6216\u4e0d\u8054\u5408\u5316\u7597\u76f8\u5173\u53e3\u8154\u9ecf\u819c\u708e\u53d1\u751f\u7387\u9ad8\uff0c\u4e25\u91cd\u8005\u53ef\u81f4\u4f4f\u9662\u5ef6\u957f\u548c\u653e\u7597\u4e2d\u65ad\uff0c\u5176\u4e2d\u53e3\u8154\u9ecf\u819c\u708e\u60a3\u8005\u7684\u653e\u7597\u4e2d\u65ad\u6bd4\u4f8b3.8\u500d\u4e8e\u975e\u53e3\u8154\u9ecf\u819c\u708e\u60a3\u8005\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">12\u3001Ionis\u5236\u836f\u516c\u53f8\u4e0e\u65d7\u4e0b\u516c\u53f8Akcea Therapeutics\u8fd1\u65e5\u516c\u5e03\u4e86\u53cd\u4e49\u836f\u7269AKCEA-APO(a)-LRx\u6cbb\u7597\u7f79\u60a3\u5fc3\u8840\u7ba1\u75be\u75c5\u4e14\u4f34\u6709\u6c34\u5e73\u5347\u9ad8\u7684\u8102\u86cb\u767d(a)[Lp(a)]\u60a3\u8005\u7684II\u671f\u4e34\u5e8a\u7814\u7a76\u7684\u79ef\u6781\u6570\u636e\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">13\u3001\u8f89\u745e\u65d7\u4e0b\u4eff\u5236\u836f\u516c\u53f8Hospira\u8fd1\u65e5\u5ba3\u5e03\uff0c\u5728\u7f8e\u56fd\u5e02\u573a\u63a8\u51faRetacrit\uff0c\u8be5\u836f\u662f\u5f3a\u751fProcrit\u548c\u5b89\u8fdbEpoGen\u7684\u751f\u7269\u4eff\u5236\u836f\uff0c\u9002\u7528\u4e8e\u8fd9\u4e24\u79cd\u54c1\u724c\u836f\u7684\u6240\u6709\u9002\u5e94\u75c7\uff0c\u5305\u62ec\u56e0\u6162\u6027\u80be\u810f\u75c5\u3001\u5316\u7597\u6216\u4f7f\u7528\u9f50\u591a\u592b\u5b9a\u6cbb\u7597HIV\u611f\u67d3\u800c\u5bfc\u81f4\u7684\u8d2b\u8840\u75c7\uff0c\u4ee5\u53ca\u7528\u4e8e\u5916\u79d1\u624b\u672f\u524d\u540e\u4ee5\u51cf\u5c11\u60a3\u8005\u56e0\u624b\u672f\u8fc7\u7a0b\u4e2d\u5931\u8840\u800c\u5bfc\u81f4\u7684\u8f93\u8840\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">14\u3001PsiOxus Therapeutics\u516c\u53f8\u4e0e\u5e15\u514b\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u7814\u7a76\u6240\u8054\u5408\u5ba3\u5e03\uff0c\u5c06\u5408\u4f5c\u5c55\u5f00\u4e00\u9879\u7814\u7a76\uff0c\u5229\u7528PsiOxus\u516c\u53f8\u57fa\u4e8e\u75c5\u6bd2\u7684\u57fa\u56e0\u7597\u6cd5\uff0c\u6cbb\u7597\u5bf9\u514d\u75ab\u7597\u6cd5\u4ea7\u751f\u6297\u6027\u7684\u5b9e\u4f53\u7624\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">15\u3001\u897f\u96c5\u56fe\u9057\u4f20\u5b66\u516c\u53f8\u8fd1\u65e5\u5ba3\u5e03\uff0c\u8bc4\u4f30\u6297\u4f53\u836f\u7269SEA-BCMA\u6cbb\u7597\u590d\u53d1\u6027\u6216\u96be\u6cbb\u6027\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u7684I\u671f\u4e34\u5e8a\u7814\u7a76\u5df2\u5b8c\u6210\u9996\u4f8b\u60a3\u8005\u7ed9\u836f\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">16\u3001UniQure\u516c\u53f8\u53d1\u5e03\u4e86\u6539\u826f\u7248\u8840\u53cb\u75c5B\u57fa\u56e0\u6cbb\u7597AMT-061\u76842b\u671f\u4e34\u5e8a\u8bd5\u9a8c\u79ef\u6781\u6570\u636e\uff0c\u60a3\u8005\u5728\u63a5\u53d7\u57fa\u56e0\u6cbb\u75976\u5468\u540e\u51dd\u8840\u56e0\u5b50IX\u53ef\u8fbe\u5230\u6b63\u5e38\u6c34\u5e73\u768431%\u3002\u8fd9\u4f7f\u5f97UniQure\u5728\u8ffd\u8d76\u7ade\u4e89\u5bf9\u624bSparkTherapeutics\u7684\u9053\u8def\u4e0a\u53d6\u5f97\u4e86\u91cd\u8981\u7684\u4e00\u6b21\u8fdb\u6b65\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">17\u3001Viking Therapeutics\u5ba3\u5e03\u4e86\u5176\u65b0\u578b\u809d\u810f\u9009\u62e9\u6027\u7532\u72b6\u817a\u53d7\u4f53\u03b2\u53d7\u4f53\u6fc0\u52a8\u5242VK2809\u76842\u671f\u7814\u7a76\u7ed3\u679c\uff0c\u8be5\u836f\u7269\u7528\u4e8e\u6cbb\u7597\u7f79\u60a3\u975e\u9152\u7cbe\u6027\u8102\u80aa\u6027\u809d\u75c5\u5e76\u4e14\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u80c6\u56fa\u9187\u5347\u9ad8\u7684\u60a3\u8005\u3002\u8be5\u7814\u7a76\u6210\u529f\u5b9e\u73b0\u4e86\u4e3b\u8981\u7ec8\u70b9\u548c\u6b21\u8981\u7ec8\u70b9\uff0c\u5e76\u8bc1\u660e\u4e86\u4ee4\u4eba\u9f13\u821e\u7684\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">18\u3001Dragonfly Therapeutics\u516c\u53f8\u5ba3\u5e03\u4e0e\u65b0\u57fa\u516c\u53f8\u7b7e\u8ba2\u4e86\u4e00\u9879\u6269\u5927\u6218\u7565\u6027\u5408\u4f5c\u534f\u8bae\u3002\u4e24\u5bb6\u516c\u53f8\u5c06\u5229\u7528Dragonfly\u516c\u53f8\u72ec\u6709\u7684TriNKET\u6280\u672f\u5e73\u53f0\uff0c\u5171\u540c\u53d1\u73b0\u3001\u5f00\u53d1\u548c\u63a8\u5e7f\u9488\u5bf9\u5b9e\u4f53\u7624\u548c\u8840\u764c\u7684\u521b\u65b0\u514d\u75ab\u7597\u6cd5\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">19\u3001Concert Pharma\u516c\u53f8\u516c\u5e03\u4e86\u5b9e\u9a8c\u6027\u6c18\u5316\u836f\u7269CTP-543\u6cbb\u7597\u4e2d\u5ea6\u81f3\u91cd\u5ea6\u6591\u79c3\u60a3\u8005IIa\u671f\u4e34\u5e8a\u7814\u7a76\u9996\u62792\u4e2a\u961f\u5217\u7684\u4e2d\u671f\u9876\u7ebf\u6570\u636e\u3002\u6570\u636e\u663e\u793a\uff0c\u5728\u6cbb\u7597\u7b2c24\u5468\uff0c\u4e0e\u5b89\u6170\u5242\u7ec4\u76f8\u6bd4\uff0c8mg CTP-543\u961f\u5217\u670947%\u7684\u60a3\u8005SALT\u603b\u8bc4\u5206\u76f8\u5bf9\u57fa\u7ebf\u964d\u4f4e\u226550%\uff0c\u8fbe\u5230\u4e86\u7814\u7a76\u7684\u4e3b\u8981\u7597\u6548\u7ec8\u70b9\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">20\u3001Quantum Genomics\u516c\u53f8\u516c\u5e03\u4e86\u5b9e\u9a8c\u6027\u964d\u538b\u836ffiribastat\u7684IIb\u671f\u4e34\u5e8a\u7814\u7a76NEW-HOPE\u7684\u79ef\u6781\u6570\u636e\u3002\u6570\u636e\u663e\u793a\uff0c\u8be5\u7814\u7a76\u8fbe\u5230\u4e86\u4e3b\u8981\u7ec8\u70b9\uff1a\u63a5\u53d7firibastat\u6cbb\u75978\u5468\u540e\uff0c\u6536\u7f29\u671fAOBP\u76f8\u5bf9\u57fa\u7ebf\u663e\u8457\u4e0b\u964d9.7mmHg\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">21\u3001Ziopharm Oncology\u516c\u53f8\u516c\u5e03\u79f0\uff0c\u5176\u4e0e\u518d\u751f\u5143\u8fbe\u6210\u4e86\u4e34\u5e8a\u5408\u4f5c\u534f\u8bae\uff0c\u5c06\u8fdb\u884c\u5728\u7814\u57fa\u56e0\u7597\u6cd5Ad-RTS-hIL-12+veledimex\u8054\u5408\u518d\u751f\u5143\u6297PD-1\u7597\u6cd5Libtayo\u00ae \u7528\u4e8e\u590d\u53d1\u6027\u80f6\u8d28\u6bcd\u7ec6\u80de\u7624\u7684\u4e34\u5e8a\u7814\u7a76\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">22\u3001Amarin\u516c\u53f8\u8fd1\u65e5\u516c\u5e03\u4e86Vascepa\u5fc3\u8840\u7ba1\u7ed3\u5c40\u7814\u7a76REDUCE-IT\u7684\u79ef\u6781\u9876\u7ebf\u6570\u636e\u3002\u521d\u6b65\u7ed3\u679c\u8bc1\u5b9e\uff0cVascepa\u4f7f\u4e3b\u8981\u7ec8\u70b9\u7684\u76f8\u5bf9\u98ce\u9669\u964d\u4f4e\u4e8625%\uff0c\u540c\u65f6\u4e5f\u8fbe\u5230\u4e86\u591a\u4e2a\u6b21\u8981\u7ec8\u70b9\uff0c\u5305\u62ec\u5c06\u5fc3\u8840\u7ba1\u6b7b\u4ea1\u51cf\u5c11\u4e8620%\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">23\u3001\u57fa\u56e0\u7597\u6cd5\u516c\u53f8Myonexus Therapeutics\u5ba3\u5e03\u542f\u52a8\u4e00\u9879\u8bc4\u4f30\u65b0\u578b\u57fa\u56e0\u7597\u6cd5MYO-101\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u7528\u4e8e\u6cbb\u7597\u03b2-\u808c\u805a\u7cd6\u75c5\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 20px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"padding-right: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: bottom;width: 203.297px;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-bottom: 10px;max-width: 100%;text-align: right;transform: translate3d(0px, 0px, 0px);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;width: 57.9219px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/section>\n<\/section>\n<section style=\"margin-bottom: 10px;max-width: 100%;text-align: right;transform: translate3d(0px, 0px, 0px);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;width: 57.9219px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"\"     style=\"background-color: rgb(238, 237, 235);border-width: 1px;border-style: solid;border-color: rgb(238, 237, 235);background-size: 22px;background-position: center center;background-repeat: no-repeat;vertical-align: middle;height: 42.7648px !important;box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible !important;width: 57.9219px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/8-1544159986.png\" alt=\"\u4e00\u5468\u836f\u95fb\u4e28\u8bfa\u534e\u5fc3\u529b\u8870\u7aed\u65b0\u836fEntresto\u4e34\u5e8a\u7ed3\u679c\u79ef\u6781 \u4ee5\u5cad\u836f\u4e1a\u53c8\u4e00\u6297\u764c\u836f\u83b7\u6279\" title=\"\u4e00\u5468\u836f\u95fb\u4e28\u8bfa\u534e\u5fc3\u529b\u8870\u7aed\u65b0\u836fEntresto\u4e34\u5e8a\u7ed3\u679c\u79ef\u6781 \u4ee5\u5cad\u836f\u4e1a\u53c8\u4e00\u6297\u764c\u836f\u83b7\u6279\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"max-width: 100%;display: inline-block;vertical-align: bottom;width: 270.391px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;text-align: center;font-size: 18px;color: rgb(142, 142, 150);line-height: 1.2;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(102, 37, 37);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u836f\u54c1\u5ba1\u6279<\/strong><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"padding-left: 10px;max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: bottom;width: 203.297px;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;transform: translate3d(0px, 0px, 0px);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;width: 57.9219px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"\"     style=\"vertical-align: middle;height: 33.6529px !important;box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible !important;width: 57.9219px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2018\/12\/3-1544159986-1.png\" alt=\"\u4e00\u5468\u836f\u95fb\u4e28\u8bfa\u534e\u5fc3\u529b\u8870\u7aed\u65b0\u836fEntresto\u4e34\u5e8a\u7ed3\u679c\u79ef\u6781 \u4ee5\u5cad\u836f\u4e1a\u53c8\u4e00\u6297\u764c\u836f\u83b7\u6279\" title=\"\u4e00\u5468\u836f\u95fb\u4e28\u8bfa\u534e\u5fc3\u529b\u8870\u7aed\u65b0\u836fEntresto\u4e34\u5e8a\u7ed3\u679c\u79ef\u6781 \u4ee5\u5cad\u836f\u4e1a\u53c8\u4e00\u6297\u764c\u836f\u83b7\u6279\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;display: inline-block;width: 677px;border-color: rgb(71, 193, 168);border-style: solid;border-width: 2px;overflow-wrap: break-word !important;\">\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section style=\"margin: 1em auto;max-width: 100%;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"padding: 3px;max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: solid;border-color: rgb(71, 198, 163);display: inline-block;overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"padding: 0.2em 1em;max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: dashed;border-color: rgb(71, 198, 163);overflow-wrap: break-word !important;\">FDA<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section style=\"padding: 10px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;font-size: 15px;line-height: 2;letter-spacing: 0px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">1\u3001\u4ee5\u5cad\u836f\u4e1a\u53d1\u5e03\u516c\u544a\u79f0\u6536\u5230\u7f8e\u56fdFDA\u7684\u901a\u77e5\uff0c\u5176\u5168\u8d44\u5b50\u516c\u53f8\u4ee5\u5cad\u4e07\u6d32\u56fd\u9645\u5236\u836f\u6709\u9650\u516c\u53f8\u7684\u5168\u8d44\u5b50\u516c\u53f8\u5317\u4eac\u4ee5\u5cad\u751f\u7269\u5de5\u7a0b\u6280\u672f\u6709\u9650\u516c\u53f8\u5411\u7f8e\u56fdFDA\u7533\u62a5\u7684\u89c4\u683c\u4e3a1 mg \u7684\u201c\u963f\u90a3\u66f2\u5511\u7247\u201d\u65b0\u836f\u7b80\u7565\u7533\u8bf7\u5df2\u83b7\u5f97\u6279\u51c6\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">2\u3001\u666e\u5229\u5236\u836f\u53d1\u5e03\u516c\u544a\u79f0\uff0c\u8fd1\u65e5\u6536\u5230\u7f8e\u56fdFDA\u7b7e\u53d1\u7684\u6ce8\u5c04\u7528\u66f4\u6614\u6d1b\u97e6\u94a0ANDA\u6279\u51c6\u901a\u77e5\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">3\u3001\u793c\u6765\u5ba3\u5e03\u5df2\u7ecf\u5411FDA\u63d0\u4ea4\u4e86\u9996\u521b\u504f\u5934\u75db\u836f\u7269Lasmiditan\u7684\u65b0\u836f\u7533\u8bf7\uff0c\u7528\u4e8e\u6cbb\u7597\u4f34\u6216\u4e0d\u4f34\u5148\u5146\u75c7\u72b6\u7684\u504f\u5934\u75db\u6210\u4eba\u60a3\u8005\u3002\u6b64\u6b21\u63d0\u4ea4\u7533\u8bf7\u7684\u4f9d\u636e\u4e3b\u8981\u662f\u8fd9\u6b3e5-HT1F\u6fc0\u52a8\u5242\u7684\u540e\u671f\u8bd5\u9a8c\u6570\u636e\u3002\u6570\u636e\u663e\u793a\uff0c\u60a3\u8005\u5728\u53e3\u670d\u8be5\u836f\u540e\uff0c\u53ef\u4ee5\u5728\u4e24\u5c0f\u65f6\u5185\u8fc5\u901f\u6e05\u9664\u5934\u75db\u75c7\u72b6\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">4\u3001\u9ed8\u6c99\u4e1c\u8fd1\u65e5\u5ba3\u5e03\uff0c\u5df2\u542f\u52a8\u5411\u7f8e\u56fdFDA\u6eda\u52a8\u63d0\u4ea4\u75ab\u82d7\u4ea7\u54c1V920\u7684\u751f\u7269\u5236\u54c1\u8bb8\u53ef\u7533\u8bf7\uff0c\u8be5\u75ab\u82d7\u7528\u4e8e\u624e\u4f0a\u5c14\u578b\u57c3\u535a\u62c9\u75c5\u6bd2\u7684\u9884\u9632\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">5\u3001\u57fa\u56e0\u6cf0\u514b\u516c\u53f8\u8868\u793a\uff0c\u7f8e\u56fdFDA\u5df2\u7ecf\u63a5\u53d7\u4e86\u5176Tecentriq\u00ae\u4e0e\u5316\u7597\u836f\u7269Abraxane\u8054\u7528\u4f5c\u4e3a\u65e0\u6cd5\u624b\u672f\u5207\u9664\u3001PD-L1\u9633\u6027\u7684\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u4e09\u9634\u6027\u4e73\u817a\u764c\u60a3\u8005\u4e00\u7ebf\u6cbb\u7597\u7684\u8865\u5145\u751f\u7269\u5236\u54c1\u8bb8\u53ef\u7533\u8bf7\uff0c\u540c\u65f6\u7ed9\u4e88\u4f18\u5148\u5ba1\u8bc4\u8ba4\u5b9a\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">6\u3001\u82f1\u56fd\u5236\u836f\u516c\u53f8Shire\u8fd1\u65e5\u5ba3\u5e03\uff0c\u7f8e\u56fdFDA\u5df2\u53d7\u7406Gattex\u7684\u8865\u5145\u65b0\u836f\u7533\u8bf7\u3002\u8be5sNDA\u7533\u8bf7\u6279\u51c6\u6269\u5927Gattex\u6ce8\u5c04\u6db2\u7684\u9002\u5e94\u75c7\uff0c\u7528\u4e8e\u4f9d\u8d56\u80a0\u5916\u652f\u6301\u7684\u77ed\u80a0\u7efc\u5408\u5f81\u513f\u79d1\u60a3\u8005\u7684\u6cbb\u7597\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">7\u3001NeuroRx\u516c\u53f8\u8fd1\u65e5\u5ba3\u5e03\uff0c\u7f8e\u56fdFDA\u5df2\u6388\u4e88\u5b9e\u9a8c\u6027\u836f\u7269NRX-101\u7a81\u7834\u6027\u836f\u7269\u8d44\u683c\uff0c\u7528\u4e8e\u6cbb\u7597\u7ecf\u6c2f\u80fa\u916e\u6216\u5176\u4ed6\u6709\u6548\u7597\u6cd5\u521d\u6b65\u7a33\u5b9a\u75c5\u60c5\u540e\u7684\u4f34\u6709\u6025\u6027\u81ea\u6740\u610f\u5ff5\u4e0e\u884c\u4e3a\u7684\u91cd\u5ea6\u53cc\u76f8\u6291\u90c1\u75c7\u60a3\u8005\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">8\u3001\u7f8e\u56fdSeattle Genetics\u516c\u53f8\u8868\u793a\u7f8e\u56fdFDA\u6388\u4e88\u516c\u53f8ADCETRIS\u4e0eCHP\u8054\u5408\u7528\u4e8e\u672a\u7ecf\u6cbb\u7597\u7684\u7cfb\u7edf\u6027\u95f4\u53d8\u6027\u5927\u7ec6\u80de\u6dcb\u5df4\u7624\u6216\u5176\u4ed6CD 30\u8868\u8fbe\u6027\u5916\u5468T\u7ec6\u80de\u6dcb\u5df4\u7624\u6cbb\u7597\u7684\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">9\u3001Theravance\u751f\u7269\u5236\u836f\u516c\u53f8\u4e0e\u8fc8\u5170\u8fd1\u65e5\u8054\u5408\u5ba3\u5e03\uff0c\u7f8e\u56fdFDA\u5df2\u6279\u51c6Yupelri\u5438\u5165\u6027\u6eb6\u6db2\uff0c\u8be5\u836f\u662f\u4e00\u79cd\u6bcf\u65e5\u4e00\u6b21\u7684\u96fe\u5316\u652f\u6c14\u7ba1\u6269\u5f20\u5242\uff0c\u53ef\u4e0e\u4efb\u610f\u7684\u6807\u51c6\u55b7\u5c04\u96fe\u5316\u5668\u517c\u5bb9\uff0c\u7528\u4e8e\u6162\u6027\u963b\u585e\u6027\u80ba\u75c5\u60a3\u8005\u7684\u7ef4\u6301\u6cbb\u7597\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">10\u3001SpringWorks Therapeutics\u516c\u53f8\u5ba3\u5e03FDA\u5df2\u6388\u4e88\u5b9e\u9a8c\u6027\u53e3\u670d\u5c0f\u5206\u5b50\u9009\u62e9\u6027\u03b3-\u5206\u6ccc\u9176\u6291\u5236\u5242nirogacestat\u6cbb\u7597\u8fdb\u884c\u6027\u3001\u4e0d\u53ef\u5207\u9664\u6027\u3001\u590d\u53d1\u6027\u6216\u96be\u6cbb\u6027\u786c\u7ea4\u7ef4\u7624\u6216\u6df1\u90e8\u7ea4\u7ef4\u7624\u75c5\u6210\u4eba\u60a3\u8005\u7684\u5feb\u901f\u901a\u9053\u5730\u4f4d\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">11\u3001\u8fd1\u65e5\u7f8e\u56fdFDA\u6388\u4e88GC4419\u836f\u7269\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\uff0c\u7528\u4e8e\u51cf\u5c11\u653e\u5c04\u6cbb\u7597\u5f15\u8d77\u7684\u4e25\u91cd\u53e3\u8154\u9ecf\u819c\u708e\u3002\u76ee\u524dGC4419\u5df2\u7ecf\u5b8c\u6210\u4e86I\u671f\u548cII\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">12\u3001MaxQ AI\u5ba3\u5e03\u5176AI\u4ea7\u54c1Accipio Ix\u5df2\u83b7\u5f97\u7f8e\u56fdFDA 510\uff08k\uff09\u8425\u9500\u8bb8\u53ef\u3002Accipio Ix\u662f\u4e00\u79cd\u4eba\u5de5\u667a\u80fd\u5de5\u4f5c\u6d41\u7a0b\u8f6f\u4ef6\uff0c\u53ef\u5e2e\u52a9\u4e34\u5e8a\u533b\u751f\u786e\u7acb\u53ef\u80fd\u51fa\u73b0\u6025\u6027\u9885\u5185\u51fa\u8840\u7684\u6210\u4eba\u60a3\u8005\u6cbb\u7597\u7684\u4f18\u5148\u7ea7\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section style=\"margin: 1em auto;max-width: 100%;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"padding: 3px;max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: solid;border-color: rgb(71, 198, 163);display: inline-block;overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"padding: 0.2em 1em;max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: dashed;border-color: rgb(71, 198, 163);overflow-wrap: break-word !important;\">NMPA<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section style=\"padding: 10px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;font-size: 15px;line-height: 2;letter-spacing: 0px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">1\u3001\u6052\u745e\u533b\u836f\u53d1\u5e03\u516c\u544a\u79f0\u8fd1\u65e5\u6536\u5230\u4e86\u56fd\u5bb6\u836f\u76d1\u5c40\u6838\u51c6\u7b7e\u53d1\u7684\u300a\u4e34\u5e8a\u8bd5\u9a8c\u901a\u77e5\u4e66\u300b\uff0c\u5e76\u5c06\u4e8e\u8fd1\u671f\u5f00\u5c55\u7f8e\u6d1b\u6614\u5eb7\u6df7\u60ac\u6ce8\u5c04\u6db2\u7684I\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002\u636e\u6089\uff0c\u7f8e\u6d1b\u6614\u5eb7\u6df7\u60ac\u6ce8\u5c04\u6db2\u662f\u4e00\u79cd\u9759\u8109\u6ce8\u5c04\u7528\u975e\u753e\u4f53\u7c7b\u6297\u708e\u836f\uff0c\u62df\u7528\u4e8e\u672f\u540e\u4e2d\u91cd\u5ea6\u75bc\u75db\u7684\u6cbb\u7597\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">2\u3001\u5e7f\u4e1c\u4f17\u751f\u836f\u4e1a\u80a1\u4efd\u6709\u9650\u516c\u53f8\u53d1\u5e03\u516c\u544a\u79f0\uff0c\u5176\u5168\u8d44\u5b50\u516c\u53f8\u5e7f\u4e1c\u534e\u5357\u836f\u4e1a\u96c6\u56e2\u6709\u9650\u516c\u53f8\u6536\u5230\u56fd\u5bb6\u836f\u76d1\u5c40\u6279\u51c6\u7b7e\u53d1\u7684\u300a\u836f\u54c1\u8865\u5145\u7533\u8bf7\u6279\u4ef6\u300b\uff0c\u534e\u5357\u836f\u4e1a\u6210\u4e3a\u56fd\u5185\u76d0\u9178\u4e8c\u7532\u53cc\u80cd\u7247\u6309\u7167\u4eff\u5236\u836f\u4e00\u81f4\u6027\u8bc4\u4ef7\u8865\u5145\u7533\u8bf7\u7533\u62a5\u7b2c\u4e8c\u5bb6\u901a\u8fc7\u7684\u4f01\u4e1a\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">3\u3001\u4fe1\u8fbe\u751f\u7269\u5ba3\u5e03\u56fd\u5bb6\u836f\u76d1\u5c40\u5df2\u53d7\u7406\u5176\u5728\u7814\u836f\u7269\u963f\u8fbe\u6728\u5355\u6297\u6ce8\u5c04\u6db2\u751f\u7269\u7c7b\u4f3c\u836f\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u3002\u8fd9\u662f\u7ee74\u6708\u4efd\u63d0\u4ea4\u4fe1\u8fea\u5229\u5355\u6297\u4e0a\u5e02\u7533\u8bf7\u5e76\u88ab\u7eb3\u5165\u4f18\u5148\u5ba1\u8bc4\u540e\uff0c\u4fe1\u8fbe\u751f\u7269\u7b2c\u4e8c\u4e2a\u83b7\u5f97NMPA\u53d7\u7406\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">4\u3001\u6cf0\u51cc\u533b\u836f\u53d1\u5e03\u516c\u544a\u79f0\uff0c\u5176\u9644\u5c5e\u516c\u53f8\u82cf\u5dde\u7b2c\u58f9\u5236\u836f\u7684\u5bcc\u9a6c\u9178\u55b9\u786b\u5e73\u7247\u5df2\u5b8c\u6210\u4e00\u81f4\u6027\u8bc4\u4ef7\u4e34\u5e8a\u5de5\u4f5c\uff0c\u6709\u5173\u7684\u6ce8\u518c\u8d44\u6599\u4e8e2018\u5e7410\u670831\u65e5\u9012\u4ea4\u81f3\u56fd\u5bb6\u836f\u76d1\u5c40\uff0c\u6709\u671b\u4e8e2019\u5e74\u7b2c\u4e00\u5b63\u5ea6\u672b\u901a\u8fc7\u5ba1\u8bc4\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">5\u3001\u6842\u6797\u4e09\u91d1\u53d1\u5e03\u516c\u544a\u79f0\uff0c\u516c\u53f8\u5df2\u7ecf\u6536\u5230\u56fd\u5bb6\u836f\u76d1\u5c40\u6838\u51c6\u7b7e\u53d1\u7684\u5168\u4eba\u6e90\u6297PD-L1\u6297\u4f53\u6ce8\u5c04\u6db2\u7684\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u6279\u4ef6\uff0c\u5c06\u5c3d\u5feb\u6309\u7167\u4e0a\u8ff0\u836f\u7269\u4e34\u5e8a\u6279\u4ef6\u8981\u6c42\u5f00\u5c55\u5168\u4eba\u6e90\u6297PD-L1\u6297\u4f53\u6ce8\u5c04\u6db2\u7684\u4e34\u5e8a\u8bd5\u9a8c\u7814\u7a76\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">6\u3001\u6839\u636eCDE\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u767b\u8bb0\u4e0e\u4fe1\u606f\u516c\u793a\u5e73\u53f0\u6700\u65b0\u6570\u636e\u663e\u793a\uff0c\u5eb7\u65b9\u751f\u7269\u65d7\u4e0bPD-1\u5355\u6297AK105\u57282018\u5e7411\u670813\u65e5\u516c\u5e03\u4e86\u8bd5\u9a8c\u65b9\u6848\uff0c\u6b63\u5f0f\u6807\u5fd7\u7740\u4e34\u5e8aIII\u671f\u8bd5\u9a8c\u7684\u5f00\u5c55\u3002\u8be5PD-1\u5355\u6297\u9488\u5bf9\u7684\u662f\u975e\u9cde\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff0cIII\u671f\u8bd5\u9a8c\u7684\u5f00\u5c55\u4e5f\u610f\u5473\u7740\u5eb7\u65b9\u751f\u7269\u8fdb\u53bb\u56fd\u4ea7\u961f\u4f0d\u7b2c\u4e8c\u68af\u961f\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">7\u3001\u6839\u636e\u4e2d\u56fd\u65b0\u53d1\u76d1\u6d4b\u6570\u636e\u5e93\u663e\u793a\uff0cCDE\u53d7\u7406\u4e86\u8c6a\u68ee\u300c\u6069\u683c\u5217\u51c0\u7247\u300d\u7684\u4e0a\u5e02\u7533\u8bf7\u3002\u6069\u683c\u5217\u51c0\u662f\u4e00\u6b3e\u65b0\u578b\u7684\u3001\u53e3\u670d\u3001\u9ad8\u9009\u62e9\u6027\u94a0-\u8461\u8404\u7cd6\u534f\u540c\u8f6c\u8fd0\u86cb\u767d2\u6291\u5236\u5242\uff0c\u5546\u54c1\u540dJardiance\uff0c\u7531\u52c3\u6797\u683c\u6bb7\u683c\u7ff0\/\u793c\u6765\u8054\u5408\u5f00\u53d1\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">8\u3001\u5409\u5229\u5fb7\u4e59\u809d\u65b0\u836f\u300c\u78f7\u4e19\u66ff\u8bfa\u798f\u97e6\u7247\u300d\u7684\u65b0\u836f\u7533\u8bf7\u83b7\u5f97\u56fd\u5bb6\u836f\u76d1\u5c40\u7684\u6ce8\u518c\u6279\u4ef6\uff0c\u83b7\u51c6\u7528\u4e8e\u6cbb\u7597\u6210\u4eba\u548c\u9752\u5c11\u5e74\u6162\u6027\u4e59\u578b\u809d\u708e\uff1b<span style=\"max-width: 100%;letter-spacing: 0px;caret-color: red;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5409\u5229\u5fb7\u6765\u8fea\u6d3e\u97e6\u7d22\u78f7\u5e03\u97e6\u7247\u5728\u4e2d\u56fd\u7684\u8fdb\u53e3\u4e0a\u5e02\u7533\u8bf7\u8fdb\u5165\u4e86\u201c\u5728\u5ba1\u6279\u201d\u9636\u6bb5\uff0c\u8fd9\u6b3e\u4e19\u809d\u795e\u836f\u5373\u5c06\u5728\u56fd\u5185\u83b7\u6279\u4e0a\u5e02\uff0c\u9020\u798f\u56fd\u5185\u7684\u809d\u708e\u60a3\u8005\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">9\u3001\u9ed8\u514b\u65d7\u4e0bPD-L1\/TGF-\u03b2\u53cc\u6297M7824\u83b7\u5f97CDE\u53d7\u7406\u3002M7824\u517c\u5177PD-1\u548cTGF-\u03b2\u53cc\u9776\u70b9\uff0c\u88ab\u79f0\u4e3a\u4e8c\u4ee3PD-1\u5355\u6297\u836f\u7269\u3002\u76ee\u524d\u5df2\u6709\u7684\u4e34\u5e8a\u7814\u7a76\u6570\u636e\u663e\u793a\u8be5\u836f\u7269\u8f83\u5176\u4ed6\u6297\u764c\u836f\u7269\u6709\u7740\u5de8\u5927\u7684\u4f18\u52bf\uff0c\u56e0\u6b64\u5e02\u573a\u524d\u666f\u5f88\u88ab\u4e1a\u754c\u770b\u597d\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section style=\"margin: 1em auto;max-width: 100%;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"padding: 3px;max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: solid;border-color: rgb(71, 198, 163);display: inline-block;overflow-wrap: break-word !important;\">\n<section class=\"\"  style=\"padding: 0.2em 1em;max-width: 100%;box-sizing: border-box;border-width: 1px;border-style: dashed;border-color: rgb(71, 198, 163);overflow-wrap: break-word !important;\">\u5176\u4ed6<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section style=\"padding: 10px;max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;font-size: 15px;line-height: 2;letter-spacing: 0px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 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