{"id":77905,"date":"2019-01-22T00:00:50","date_gmt":"2019-02-01T06:11:05","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/77905\/"},"modified":"2019-02-01T14:11:11","modified_gmt":"2019-02-01T06:11:11","slug":"1c02734f12","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/77905\/","title":{"rendered":"\u6700\u8fd1\u65b0\u836f\u83b7\u6279\uff1a\u6297\u51dd\u53c8\u6dfb\u5927\u54c1\u79cdEdoxaban\uff08 \u827e\u591a\u6c99\u73ed\uff09"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<section  label=\"Powered by 135editor.com\" style=\"max-width: 100%;font-size: 16px;font-family: \u5fae\u8f6f\u96c5\u9ed1;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(64, 118, 0);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzUyNTgyNjUzMw==&amp;mid=2247488530&amp;idx=1&amp;sn=1547ec9b4f24b656700a852735903c46&amp;scene=21#wechat_redirect\" target=\"_blank\"  style=\"color: rgb(87, 107, 149);-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u7834\u7eaa\u5f55\uff0c2018\u5e74\u6211\u56fdNMPA\u6279\u51c659\u6b3e\u65b0\u836f\u4e0a\u5e02\uff08\u9644\u8868\u683c\uff09<\/a><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;word-wrap: break-word !important;\">\n<section style=\"margin-top: 0.8em;margin-bottom: 0.5em;max-width: 100%;line-height: 32px;font-weight: bold;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;float: left;color: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;width: 0px;height: 0px;color: rgb(254, 254, 254);text-align: center;border-top: 35px solid rgb(128, 177, 53);border-left: 14px solid transparent;border-right: 14px solid transparent;word-wrap: break-word !important;\">\n<section style=\"margin-top: -30px;margin-left: -5px;max-width: 100%;color: inherit;line-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;color: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\"><em class=\"\" style=\"max-width: 100%;color: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\">1<\/em><\/strong><\/span><\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"margin-left: 36px;max-width: 100%;box-sizing: border-box;color: rgb(128, 177, 53);border-color: rgb(128, 177, 53);word-wrap: break-word !important;\">\u827e\u591a\u6c99\u73ed\u83b7\u6279\u4fe1\u606f\uff1a<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"     style=\"zoom: 0.8;box-sizing: border-box !important;word-wrap: break-word !important;width: 677px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/02\/10-1549001466.jpeg\" alt=\"\u6700\u8fd1\u65b0\u836f\u83b7\u6279\uff1a\u6297\u51dd\u53c8\u6dfb\u5927\u54c1\u79cdEdoxaban\uff08 \u827e\u591a\u6c99\u73ed\uff09\" title=\"\u6700\u8fd1\u65b0\u836f\u83b7\u6279\uff1a\u6297\u51dd\u53c8\u6dfb\u5927\u54c1\u79cdEdoxaban\uff08 \u827e\u591a\u6c99\u73ed\uff09\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">1.\u53e6\u5916\u4e00\u540c\u83b7\u6279\u768415mg\uff0c60mg\u89c4\u683c\u3002<br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">2.\u672c\u54c1\u539f\u7814\u65e5\u672c\u7b2c\u4e00\u4e09\u5171\u5236\u836f\uff0cEdoxaban\u662f\u4e00\u79cd\u53e3\u670d\u7684\u51dd\u8840\u56e0\u5b50Xa\uff08factor Xa\uff09\u6291\u5236\u5242\u30022011\u5e744\u6708\u7387\u5148\u5728\u65e5\u672c\u4e0a\u5e02\uff0c\u7528\u4e8e\u9759\u8109\u8840\u6813\u6813\u585e\u75c7(VTE)\u30022015\u5e741\u6708\u5728\u7f8e\u56fd\u83b7\u6279\u7528\u4e8e\u964d\u4f4e\u975e\u5fc3\u810f\u74e3\u819c\u75c5\u5f15\u8d77\u7684\u623f\u98a4\u60a3\u8005\u5352\u4e2d\u548c\u5371\u9669\u8840\u6813(\u7cfb\u7edf\u6027\u6813\u585e)\u98ce\u9669\uff08\u9646\u7eed\u83b7\u5f97\u5176\u4ed6\u9002\u5e94\u75c7\uff09\u3002<\/span><span style=\"max-width: 100%;font-size: 14px;color: rgb(171, 25, 66);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u827e\u591a\u6c99\u73ed\u6210\u4e3a\u7ee7\u8fbe\u6bd4\u52a0\u7fa4\u916f\u3001\u5229\u4f10\u6c99\u73ed\u548c\u963f\u54cc\u6c99\u73ed\u4e4b\u540e\u7b2c\u56db\u4e2a\u83b7\u5f97FDA\u6279\u51c6\u7684\u65b0\u578b\u53e3\u670d\u6297\u51dd\u836f\uff08NOAC\uff09<\/strong><\/span><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">(Betrixaban2018\u5e74\u83b7\u6279)\u3002\u6b27\u76df\u57282015\u5e746\u6708\u83b7\u6279\u4e0a\u5e02\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"     style=\"zoom: 0.8;box-sizing: border-box !important;word-wrap: break-word !important;width: 512px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/02\/9-1549001466.png\" alt=\"\u6700\u8fd1\u65b0\u836f\u83b7\u6279\uff1a\u6297\u51dd\u53c8\u6dfb\u5927\u54c1\u79cdEdoxaban\uff08 \u827e\u591a\u6c99\u73ed\uff09\" title=\"\u6700\u8fd1\u65b0\u836f\u83b7\u6279\uff1a\u6297\u51dd\u53c8\u6dfb\u5927\u54c1\u79cdEdoxaban\uff08 \u827e\u591a\u6c99\u73ed\uff09\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;line-height: 1.75em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">3.\u56fd\u5185<\/span><span style=\"max-width: 100%;font-size: 14px;color: rgb(171, 25, 66);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5316<\/strong><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5408\u7269\u4e13\u5229<\/strong><\/span><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">2022\u5e74\u5230\u671f\uff0c\u518d\u4e0d\u83b7\u6279\uff0c\u57284+7\u4e4b\u540e\u53ef\u80fd\u610f\u4e49\u4e0d\u5927\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">4.\u5728\u56fd\u5185\u767b\u8bb0\u6ce8\u518c\u4e34\u5e8a\u9002\u5e94\u75c7\u4e3a\u9759\u8109\u8840\u6813\u6813\u585e, \u623f\u98a4\uff1b\u53ef\u80fd\u4e3a\u83b7\u6279\u9002\u5e94\u75c7\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"     style=\"zoom: 0.8;box-sizing: border-box !important;word-wrap: break-word !important;width: 677px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/02\/9-1549001467.jpeg\" alt=\"\u6700\u8fd1\u65b0\u836f\u83b7\u6279\uff1a\u6297\u51dd\u53c8\u6dfb\u5927\u54c1\u79cdEdoxaban\uff08 \u827e\u591a\u6c99\u73ed\uff09\" title=\"\u6700\u8fd1\u65b0\u836f\u83b7\u6279\uff1a\u6297\u51dd\u53c8\u6dfb\u5927\u54c1\u79cdEdoxaban\uff08 \u827e\u591a\u6c99\u73ed\uff09\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u63a8\u6d4b\u53ef\u80fd\u505a\u5b8c\u4e00\u671f\uff0c<\/span><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;color: rgb(171, 25, 66);box-sizing: border-box !important;word-wrap: break-word !important;\">\u901a\u8fc7\u63d0\u4ea4\u7b26\u5408NMPA\u5ba1\u8bc4\u8981\u6c42\u7684\u5883\u5916\u6570\u636e\uff0c\u6709\u6761\u4ef6\u6279\u51c6\u4e0a\u5e02<\/span><\/strong><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">\uff1f<\/span><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">5.\u8fdb\u53e3\u7533\u8bf7\u57282017\u5e7412\u6708\u83b7\u5f97\u53d7\u7406\uff0c\u83b7NMPA\u6279\u51c6\u4e0a\u5e02\u8017\u65f6\u4e00\u5e74\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"     style=\"zoom: 0.8;box-sizing: border-box !important;word-wrap: break-word !important;width: 677px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/02\/1-1549001468.jpeg\" alt=\"\u6700\u8fd1\u65b0\u836f\u83b7\u6279\uff1a\u6297\u51dd\u53c8\u6dfb\u5927\u54c1\u79cdEdoxaban\uff08 \u827e\u591a\u6c99\u73ed\uff09\" title=\"\u6700\u8fd1\u65b0\u836f\u83b7\u6279\uff1a\u6297\u51dd\u53c8\u6dfb\u5927\u54c1\u79cdEdoxaban\uff08 \u827e\u591a\u6c99\u73ed\uff09\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">6.\u56fd\u4ea7\u827e\u591a\u6c99\u73ed\uff08\u4ee5\u524d\u7533\u62a5\u540d\u591a\u4e3a\uff1a\u4f9d\u5ea6\u6c99\u73ed\uff09\u4eff\u5236\u836f\u5747\u5728722\u4e4b\u524d\u63d0\u4ea43.1\u7c7b\u7533\u8bf7\uff0c\u76ee\u524d\u6682\u672a\u770b\u5230\u6700\u65b0\u7684\u7533\u62a5\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;word-wrap: break-word !important;\">\n<section style=\"margin-top: 0.8em;margin-bottom: 0.5em;max-width: 100%;line-height: 32px;font-weight: bold;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;float: left;color: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;width: 0px;height: 0px;color: rgb(254, 254, 254);text-align: center;border-top: 35px solid rgb(128, 177, 53);border-left: 14px solid transparent;border-right: 14px solid transparent;word-wrap: break-word !important;\">\n<section style=\"margin-top: -30px;margin-left: -5px;max-width: 100%;color: inherit;line-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;color: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\"><em class=\"\"  style=\"max-width: 100%;color: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\">2<\/em><\/strong><\/span><\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"margin-left: 36px;max-width: 100%;box-sizing: border-box;color: rgb(128, 177, 53);border-color: rgb(128, 177, 53);word-wrap: break-word !important;\">\u6297\u51dd\u5e02\u573a\uff1a<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">2018\u5e746\u6708\uff0c\u6743\u5a01\u671f\u520a\u300aNature Reviews Drug Discovery\u300b\u5728\u7ebf\u53d1\u8868\u4e86\u300aThe market of oral anticoagulants\u300b\u4e00\u6587\uff0c\u7b80\u8ff0\u4e86\u53e3\u670d\u6297\u51dd\u8840\u836f\u7269(OACs)\u5e02\u573a\u548c\u8fdb\u5c55\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u57282017\u5e74\uff0c\u5168\u7403\u6297\u51dd\u836f\u9500\u552e\u989d\u5927\u7ea6338\u4ebf\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u957f16%\u3002\u5176\u4e2d\u65b0\u578b\u53e3\u670d\u6297\u51dd\u836f\uff08NOACs\uff09\u5360\u636e172\u4ebf\u7f8e\u5143\uff0c\u5e02\u573a\u5360\u6709\u7387\u572851%\u3002\u76f8\u6bd42016\u5e74\uff0cNOACs\u9500\u552e\u989d\u589e\u5e45\u4e3a31%\uff0c2013-2017\u5e74\u4e2d\u7684\u590d\u5408\u5e74\u589e\u957f\u7387\u4e3a44%\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"     style=\"zoom: 0.8;box-sizing: border-box !important;word-wrap: break-word !important;width: 554px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/02\/6-1549001468.jpg\" alt=\"\u6700\u8fd1\u65b0\u836f\u83b7\u6279\uff1a\u6297\u51dd\u53c8\u6dfb\u5927\u54c1\u79cdEdoxaban\uff08 \u827e\u591a\u6c99\u73ed\uff09\" title=\"\u6700\u8fd1\u65b0\u836f\u83b7\u6279\uff1a\u6297\u51dd\u53c8\u6dfb\u5927\u54c1\u79cdEdoxaban\uff08 \u827e\u591a\u6c99\u73ed\uff09\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5229\u4f10\u6c99\u73ed2017\u5e74\u9500\u552e\u989d\u4e3a76\u4ebf\u7f8e\u5143\uff0c\u963f\u54cc\u6c99\u73ed2017\u5e74\u9500\u552e\u989d\u4e3a69\u4ebf\u7f8e\u5143\uff0c\u8fbe\u6bd4\u52a0\u7fa4\u916f\u548c<\/span><span style=\"max-width: 100%;font-size: 14px;color: rgb(171, 25, 66);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u827e\u591a\u6c99\u73ed<\/strong><\/span><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u7684\u9500\u552e\u989d\u5206\u522b\u4e3a20\u4ebf\u7f8e\u5143\u548c<\/span><span style=\"max-width: 100%;font-size: 14px;color: rgb(171, 25, 66);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">5.71\u4ebf\u7f8e\u5143<\/strong><\/span><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u3002\u5168\u7403\u65b0\u578b\u53e3\u670d\u6297\u51dd\u836fNOACs\u9500\u552e\u989d\u4e2d\uff0c<\/span><span style=\"max-width: 100%;font-size: 14px;color: rgb(171, 25, 66);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u7f8e\u56fd\u5360\u5168\u7403\u9500\u552e\u989d\u768455%\uff0c\u6b27\u6d32\u7ea628%\uff0c\u65e5\u672c\u5e02\u573a\u6bd4\u4f8b\u4e3a8%<\/strong><\/span><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">\uff0c\u5176\u5b83\u5730\u533a\u5171\u53608%\uff08\u4e2d\u56fd\u5e02\u573a\u5728\u5185\uff09\u3002\u636e\u6587\u7ae0\u9884\u8ba1\uff0cNOACs\u836f\u7269\u7684\u5e02\u573a\u57282020\u5e74\u8fbe\u5230\u5cf0\u503c\uff0c220\u4ebf\u7f8e\u5143\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<section class=\"\"     style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;word-wrap: break-word !important;\">\n<section style=\"padding-top: 10px;padding-bottom: 10px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section  style=\"max-width: 100%;width: 677px;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;display: inline-block;width: auto;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\"  style=\"padding-right: 5px;padding-left: 5px;max-width: 100%;box-sizing: border-box;letter-spacing: 1.5px;color: rgb(128, 177, 53);word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u8f6c\u53d1\u670b\u53cb\u5708\uff0c\u51ed\u622a\u56fe\u53d1\u9001\u836f\u878d\u5708\u5fae\u4fe1\u516c\u4f17\u53f7\u540e\u53f0\u53ef\u83b7\u5f97\u539f\u6587\u7ae0\u5168\u6587\uff0c\u540e\u53f0\u7b2c\u4e8c\u5929\u7edf\u4e00\u56de\u590d\uff01<\/span><\/section>\n<section  style=\"margin-top: 6px;max-width: 100%;width: 630px;height: 1px;color: rgb(255, 255, 255);background: rgb(128, 177, 53);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<section  style=\"margin-top: 3px;max-width: 100%;width: 630px;height: 1px;color: rgb(255, 255, 255);background: rgb(128, 177, 53);box-sizing: border-box !important;word-wrap: break-word !important;\"><\/section>\n<section style=\"margin-top: -17px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"padding-right: 5px;padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;font-size: 12px;color: rgb(128, 177, 53);background: rgb(254, 254, 254);word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u25b2\u25b2\u25b2<\/span><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br  \/><\/p>\n<section class=\"\"   style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;word-wrap: break-word !important;\">\n<section style=\"margin-top: 0.8em;margin-bottom: 0.5em;max-width: 100%;line-height: 32px;font-weight: bold;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;float: left;color: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;width: 0px;height: 0px;color: rgb(254, 254, 254);text-align: center;border-top: 35px solid rgb(128, 177, 53);border-left: 14px solid transparent;border-right: 14px solid transparent;word-wrap: break-word !important;\">\n<section style=\"margin-top: -30px;margin-left: -5px;max-width: 100%;color: inherit;line-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;color: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\"><em class=\"\"  style=\"max-width: 100%;color: inherit;box-sizing: border-box !important;word-wrap: break-word !important;\">3<\/em><\/strong><\/span><\/section>\n<\/section>\n<\/section>\n<section class=\"\"  style=\"margin-left: 36px;max-width: 100%;box-sizing: border-box;color: rgb(128, 177, 53);border-color: rgb(128, 177, 53);word-wrap: break-word !important;\">\u56fd\u4ea7\u51dd\u8840\u56e0\u5b50Xa\u6291\u5236\u5242\uff0c\u6c99\u73ed\u7c7b\u4eff\u5236\u836f\uff1a<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u963f\u54cc\u6c99\u73ed\uff0c\u7533\u62a5\u7ade\u4e89\u6fc0\u70c8\uff0c\u542f\u52a8BE\u7684\u66f4\u751a\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"     style=\"zoom: 0.8;box-sizing: border-box !important;word-wrap: break-word !important;width: 677px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/02\/0-1549001469.jpeg\" alt=\"\u6700\u8fd1\u65b0\u836f\u83b7\u6279\uff1a\u6297\u51dd\u53c8\u6dfb\u5927\u54c1\u79cdEdoxaban\uff08 \u827e\u591a\u6c99\u73ed\uff09\" title=\"\u6700\u8fd1\u65b0\u836f\u83b7\u6279\uff1a\u6297\u51dd\u53c8\u6dfb\u5927\u54c1\u79cdEdoxaban\uff08 \u827e\u591a\u6c99\u73ed\uff09\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5229\u4f10\u6c99\u73ed\u4eff\u5236\u836f2018\u5e74\u4ee5\u540e\u7684\u7533\u62a5\uff1a<\/span><\/strong><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"          style=\"zoom: 0.8;box-sizing: border-box !important;word-wrap: break-word !important;width: 556px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/02\/3-1549001470.jpeg\" alt=\"\u6700\u8fd1\u65b0\u836f\u83b7\u6279\uff1a\u6297\u51dd\u53c8\u6dfb\u5927\u54c1\u79cdEdoxaban\uff08 \u827e\u591a\u6c99\u73ed\uff09\" title=\"\u6700\u8fd1\u65b0\u836f\u83b7\u6279\uff1a\u6297\u51dd\u53c8\u6dfb\u5927\u54c1\u79cdEdoxaban\uff08 \u827e\u591a\u6c99\u73ed\uff09\"  \/><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u7b49\u5230\u76f8\u5173\u4e13\u5229\u8fc7\u671f\uff0c\u83b7\u6279\u4e0a\u5e02\u9500\u552e\uff0c\u5927\u5c0f\u4eff\u5236\u836f\u4f01\u4e1a\u8fd8\u662f\u4f1a\u62fc\u4ef7\u683c\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(171, 25, 66);box-sizing: border-box !important;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u66f4\u591a\u76f8\u5173\u836f\u4f01\u4ea7\u54c1\u4fe1\u606f\uff0c\u52a0\u5165\u836f\u878d\u5708\u3002<\/span><\/strong><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;color: rgb(136, 136, 136);box-sizing: border-box !important;word-wrap: break-word !important;\">\u53c2\u8003:<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;color: rgb(136, 136, 136);box-sizing: border-box !important;word-wrap: break-word !important;\">NMPA\/CDE\uff1b<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;color: rgb(136, 136, 136);box-sizing: border-box !important;word-wrap: break-word !important;\">\u836f\u878d\u6570\u636e\uff0cPharnex &nbsp;Datamonitor;<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;color: rgb(136, 136, 136);box-sizing: border-box !important;word-wrap: break-word !important;\">FDA\/EMA\uff1b<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;color: rgb(136, 136, 136);box-sizing: border-box !important;word-wrap: break-word !important;\">\u76f8\u5173\u516c\u53f8\u516c\u5f00\u62ab\u9732\u7b49\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<section  class=\"\" style=\"max-width: 100%;font-family: -apple-system-font, BlinkMacSystemFont, Arial, sans-serif;letter-spacing: 0.544px;line-height: 25.6px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;line-height: 25.6px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"margin: 6px auto;max-width: 100%;text-align: center;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;display: inline-block;border-top: 20px solid transparent;border-right: 15px solid rgb(40, 142, 213);border-bottom: 0px solid transparent;border-left-color: rgb(40, 142, 213);height: 15px;vertical-align: top;word-wrap: break-word !important;\"><\/section>\n<section style=\"padding: 5px 10px;max-width: 100%;box-sizing: border-box;display: inline-block;height: 35px;color: rgb(255, 255, 255);border-width: 1px;border-style: solid;border-color: rgb(40, 142, 213);background-color: rgb(254, 254, 254);word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;\">\u731c\u4f60\u559c\u6b22<\/span><\/section>\n<section style=\"max-width: 100%;box-sizing: border-box;display: inline-block;border-top: 20px solid transparent;border-right-color: rgb(40, 142, 213);border-bottom: 0px solid transparent;border-left: 15px solid rgb(40, 142, 213);height: 15px;vertical-align: top;word-wrap: break-word !important;\"><\/section>\n<section style=\"margin-top: -16px;max-width: 100%;box-sizing: border-box;height: 1px;border-top: 1px solid rgb(40, 142, 213);word-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<ul class=\"list-paddingleft-2\" style=\"\">\n<li>\n<section  class=\"\" style=\"max-width: 100%;letter-spacing: 0.544px;line-height: 25.6px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzUyNTgyNjUzMw==&amp;mid=2247488530&amp;idx=1&amp;sn=1547ec9b4f24b656700a852735903c46&amp;scene=21#wechat_redirect\" target=\"_blank\" textvalue=\"\u7834\u7eaa\u5f55\uff0c2018\u5e74\u6211\u56fdNMPA\u6279\u51c659\u6b3e\u65b0\u836f\u4e0a\u5e02\uff08\u9644\u8868\u683c\uff09\"  style=\"color: rgb(87, 107, 149);-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;font-family: \u5fae\u8f6f\u96c5\u9ed1;font-size: 14px;box-sizing: border-box !important;word-wrap: break-word !important;\">\u7834\u7eaa\u5f55\uff0c2018\u5e74\u6211\u56fdNMPA\u6279\u51c659\u6b3e\u65b0\u836f\u4e0a\u5e02\uff08\u9644\u8868\u683c\uff09<\/a><\/p>\n<\/section>\n<\/li>\n<li>\n<section  class=\"\" style=\"max-width: 100%;letter-spacing: 0.544px;line-height: 25.6px;box-sizing: border-box !important;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\"><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzUyNTgyNjUzMw==&amp;mid=2247488530&amp;idx=3&amp;sn=1fdee830fa6915fc261caa70ab5a7814&amp;scene=21#wechat_redirect\" target=\"_blank\" 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