{"id":78026,"date":"2019-01-07T00:00:50","date_gmt":"2019-02-01T06:12:44","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/78026\/"},"modified":"2019-02-01T14:12:46","modified_gmt":"2019-02-01T06:12:46","slug":"2f2894051d","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/78026\/","title":{"rendered":"\u3010\u901f\u5ea6PK\u3011\u9ed8\u514bPD-L1 \/TGF\u03b2\u83b7\u6279\u4e34\u5e8a\uff0c\u6052\u745e\u542f\u52a8\u524d\u5217\u817a\u764c"},"content":{"rendered":"
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\"\u3010\u901f\u5ea6PK\u3011\u9ed8\u514bPD-L1<\/em><\/p>\n

2019|\u7b2c\u4e00\u5c4a\u836f\u878d\u5708CBV\u9ad8\u5cf0\u8bba\u575b\u8bf7\u626b\u4e0b\u65b9\u4e8c\u7ef4\u7801\u62a5\u540d\uff0c\u540d\u989d\u6709\u9650<\/strong><\/h3>\n


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\"\u3010\u901f\u5ea6PK\u3011\u9ed8\u514bPD-L1<\/p>\n


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Merck KGaA;Baxter Oncology GmbH;\u9ed8\u514b\u96ea\u5170\u8bfa \u81ea\u4e3b\u5f00\u53d1\u7684\u53cc\u6297M7824 (MSB0011359C)\uff0c\u56fd\u5916\u6700\u5feb\u8fdb\u5c55\u4e8c\u671f\u4e34\u5e8a\u3002<\/strong><\/span><\/p>\n

\u672c\u54c1\u4e3a\u6cbb\u7597\u665a\u671f\u5b9e\u4f53\u7624\u7684 PD-L1 \/TGF\u03b2 \u6297\u4f53\u878d\u5408\u86cb\u767d\u836f\u7269\u3002M7824\u4e00\u7aef\u8bc6\u522b\u7ed3\u5408PD-L1\u7684\u6297\u4f53\uff0c\u53e6\u4e00\u7aef\u7528\u4e8etrap TGF-\u03b2\u7684\u53d7\u4f53\uff0c\u540c\u65f6\u963b\u65ad\u76f8\u4e92\u72ec\u7acb\u53c8\u5f7c\u6b64\u4e92\u8865\u7684PD-L1\u901a\u8def\u548cTGF-\u03b2\u901a\u8def\u80fd\u591f\u4fc3\u8fdb\u514d\u75ab\u7ec6\u80de\u5bf9\u80bf\u7624\u7ec6\u80de\u7684\u6740\u4f24\u3002<\/span><\/p>\n

\"\u3010\u901f\u5ea6PK\u3011\u9ed8\u514bPD-L1<\/p>\n

CLIN CANCER RES\u66fe\u57282018\u5e743\u6708\u53d1\u8868\u4e86\u4e00\u7bc7\u6587\u7ae0\uff0c\u62a5\u9053\u4e86M7824\u6cbb\u7597\u665a\u671f\u5b9e\u4f53\u80bf\u7624\u7684\u521d\u6b65\u4e34\u5e8a\u7ed3\u679c\u3002<\/span><\/p>\n

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 \u8bd5\u9a8c\u901a\u4fd7\u9898\u76ee\uff1a<\/td>\n\u8bc4\u4f30SHR-1701\u6cbb\u7597\u665a\u671f\u6076\u6027\u5b9e\u4f53\u80bf\u7624\u53d7\u8bd5\u8005\u7684I\u671f\u4e34\u5e8a\u7814\u7a76<\/td>\n<\/tr>\n
 \u8bd5\u9a8c\u4e13\u4e1a\u9898\u76ee\uff1a<\/td>\n\u8bc4\u4f30PD-L1\/TGF-\u03b2RII\u6297\u4f53SHR-1701\u6cbb\u7597\u665a\u671f\u6076\u6027\u5b9e\u4f53\u80bf\u7624\u53d7\u8bd5\u8005\u7684\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u7684I\u671f\u4e34\u5e8a\u7814\u7a76<\/td>\n<\/tr>\n
 \u8bd5\u9a8c\u65b9\u6848\u7f16\u53f7\uff1a<\/td>\nSHR-1701-I-102\uff1b1.0<\/td>\n<\/tr>\n
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 \u836f\u7269\u540d\u79f0\uff1a<\/td>\nSHR-1701\u6ce8\u5c04\u6db2<\/td>\n<\/tr>\n
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\u53c2\u8003\uff1a<\/span><\/strong><\/span><\/p>\n

NMPA\/CDE\uff1b<\/span><\/h1>\n

\u836f\u878d\u6570\u636e\uff0cPharnex  Datamonitor;<\/span><\/p>\n

\u76f8\u5173\u516c\u53f8\u516c\u5f00\u62ab\u9732\u7b49\u3002<\/span><\/p>\n


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\u5728\u6587\u7ae0\u540e\u7559\u8a00\uff0c\u5408\u9002\u7684\u53ef\u6dfb\u52a0Research\u533b\u836f\u4ebaDaniel\u5fae\u4fe1\u3002<\/p>\n


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2019|\u7b2c\u4e00\u5c4a\u836f\u878d\u5708CBV\u9ad8\u5cf0\u8bba\u575b\u8bf7\u626b\u4e0b\u65b9\u4e8c\u7ef4\u7801\u62a5\u540d\uff0c\u540d\u989d\u6709\u9650 \u4e00.\u9ed8\u514bPD-L1 \/TGF\u03b2 \u836f\u878d\u6570\u636e\u76d1\u6d4b […]<\/p>\n","protected":false},"author":1,"featured_media":78027,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/78026"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=78026"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/78026\/revisions"}],"predecessor-version":[{"id":78032,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/78026\/revisions\/78032"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/78027"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=78026"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=78026"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=78026"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}