{"id":78320,"date":"2019-01-08T00:00:50","date_gmt":"2019-02-01T06:15:58","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/78320\/"},"modified":"2019-02-01T14:16:00","modified_gmt":"2019-02-01T06:16:00","slug":"58bbfb24c4","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/78320\/","title":{"rendered":"\u76d8\u70b92018\u5168\u7403\u65b0\u4e0a\u5e02\u768439\u4e2a\u751f\u7269\u836f"},"content":{"rendered":"
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\u76d8\u70b92018\u5168\u7403\u65b0\u4e0a\u5e02\u768439\u4e2a\u751f\u7269\u836f<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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21\u4e16\u7eaa\u662f\u751f\u547d\u79d1\u5b66\u7684\u4e16\u7eaa\uff0c\u5f53\u524d\u7f8e\u56fd\u79d1\u5b66\u9662\u6709\u8d85\u8fc7\u534a\u6570\u7684\u9662\u58eb\u662f\u4ece\u4e8b\u751f\u547d\u79d1\u5b66\u9886\u57df\u7684\u7814\u7a76\uff1b\u7f8e\u56fd\u8054\u90a6\u653f\u5e9c\u7528\u4e8e\u8d44\u52a9\u79d1\u5b66\u7814\u7a76\u7684\u9884\u7b97\u4e2d\uff0c\u5176\u4e2d\u6709\u4e00\u534a\u4ee5\u4e0a\u7528\u4e8e\u751f\u547d\u79d1\u5b66\u7684\u7814\u7a76\u3002\u6240\u4ee5\u76f8\u5bf9\u5316\u5b66\u836f\u6765\u8bf4\uff0c\u751f\u7269\u836f\u5728\u4eba\u7c7b\u75be\u75c5\u7684\u6cbb\u7597\u9886\u57df\u53d1\u5c55\u8d8a\u6765\u8d8a\u5feb\u3002<\/p>\n

       <\/p>\n

\u751f\u7269\u6280\u672f\u836f\u7b80\u79f0\u751f\u7269\u836f\uff0c\u4e3b\u8981\u5206\u4e3a\u91cd\u7ec4\u86cb\u767d\u8d28\u836f\u7269\u3001\u91cd\u7ec4\u591a\u80bd\u836f\u7269\u3001\u91cd\u7ec4DNA\u836f\u4ee5\u53ca\u6cbb\u7597\u836f\u7b49\u3002\u636e\u6d4b\u7b972022\u5e74\u5168\u7403\u751f\u7269\u836f\u5e02\u573a\u5c06\u8fbe3260\u4ebf\u7f8e\u5143\u3002\u540c\u65f6Frost&Sullivan\u9884\u6d4b\u4e2d\u56fd\u751f\u7269\u836f\u5e02\u573a2021\u5e74\u4e5f\u5c06\u8fbe3269\u4ebf\u5143\u89c4\u6a21\u3002\u56de\u987e2018\u5e74\u5168\u7403\u4e0a\u5e02\u4e8693\u4e2a\u65b0\u836f\u3002\u5176\u4e2d\u5316\u5b66\u836f54\u4e2a\uff0c\u751f\u7269\u836f39\u4e2a\u3002<\/p>\n

       <\/p>\n

\u9996\u5148\u6211\u4eec\u7efc\u5408\u770b\u4e00\u4e0b\u8fd939\u4e2a\u836f\u7269\u7684\u9776\u70b9\u548c\u7814\u53d1\u4fe1\u606f\uff1a<\/p>\n


<\/p>\n

\"\u76d8\u70b92018\u5168\u7403\u65b0\u4e0a\u5e02\u768439\u4e2a\u751f\u7269\u836f\"<\/p>\n


<\/p>\n

 1. Caplacizumab<\/strong><\/span><\/p>\n

       <\/p>\n

Ablynx\u7814\u53d1\u7684Caplacizumab\u4e8e2018\u5e748\u670831\u65e5\u83b7EMA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3aCablivi\u00ae\u3002\u662f\u4e00\u79cd\u6297\u8840\u7ba1\u6027\u8840\u53cb\u75c5\u56e0\u5b50\u7684\u7eb3\u7c73\u6297\u4f53\uff0c\u88ab\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u83b7\u5f97\u6027\u8840\u6813\u6027\u8840\u5c0f\u677f\u51cf\u5c11\u6027\u7d2b\u765c\uff08TTP\uff09\u3002<\/p>\n

       <\/p>\n

2. Darvadstrocel<\/strong><\/span><\/p>\n

       <\/p>\n

Darvadstrocel 2018\u5e743\u670823\u65e5\u88abEMA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3aAlofisel\u00ae\uff0c\u662f\u4e00\u79cd\u8102\u80aa\u7ec6\u80de\u5f02\u4f53\u66ff\u4ee3\u7597\u6cd5\uff0c\u542b\u4ece\u8102\u80aa\u4e2d\u63d0\u53d6\u7684\u4eba\u540c\u79cd\u5f02\u4f53\u95f4\u8d28\uff0c\u8be5\u4ea7\u54c1\u88ab\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u809b\u7ba1\u76f4\u80a0\u7618\u3002<\/p>\n

       <\/p>\n

3. YS-ON-001<\/strong><\/span><\/p>\n

       <\/p>\n

YS-ON-001\u662f\u7531\u4f9d\u751f\u751f\u7269\u5f00\u53d1\u5e76\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3a\u4f9d\u7ef4\u5361\u00ae\uff0c\u4e8e2018\u5e74\u5728\u67ec\u57d4\u5be8\u83b7\u6279\u4e0a\u5e02\u9500\u552e\uff0c\u7528\u4e8e\u6cbb\u7597\u4e73\u817a\u764c\u3001\u7ed3\u76f4\u80a0\u764c\u3001\u809d\u764c\u3001\u80ba\u764c\u548c\u80c3\u764c\u7b49\u5b9e\u4f53\u7624<\/p>\n

       <\/p>\n

4. Etanercept biosimilar<\/strong><\/span><\/p>\n

       <\/p>\n

\u6301\u7530\u5236\u53d1\u7684\u4f9d\u90a3\u897f\u666e\uff08Etanercept\uff09\u751f\u7269\u7c7b\u4f3c\u836f\u4e8e2018\u5e741\u670819\u65e5\u83b7PMDA\u6279\u51c6\u4e0a\u5e02\uff0c\u4f9d\u90a3\u897f\u666e\u751f\u7269\u7c7b\u4f3c\u836f\u662f\u4e00\u79cd\u80bf\u7624\u574f\u6b7b\u56e0\u5b50\uff08TNF\uff09\u963b\u65ad\u5242\uff0c\u80fd\u7279\u5f02\u6027\u7ed3\u5408\u4e8eTNF\u5206\u5b50\uff0c\u6291\u5236TNF-\u03b1 \u548cTNF-\u03b2\u4e0e\u7ec6\u80de\u8868\u9762TNF\u53d7\u4f53\u7684\u7ed3\u5408\u3002\u8be5\u836f\u7528\u4e8e\u6cbb\u7597\u7c7b\u98ce\u6e7f\u6027\u5173\u8282\u708e\u548c\u5e7c\u5e74\u7279\u53d1\u6027\u5173\u8282\u708e\u3002<\/p>\n

       <\/p>\n

5. Adalimumab biosimilar<\/strong><\/span><\/p>\n

       <\/p>\n

Hulio\u00ae<\/p>\n

       <\/p>\n

FKB-327\u7531\u5bcc\u58eb\u534f\u548c\u9e92\u9e9f\u751f\u7269\u516c\u53f8\u7814\u53d1\uff0c\u4e8e2018\u5e7410\u6708\u83b7EMA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3aHulio\u00ae\u3002\u662f\u4e00\u79cd\u9776\u5411\u4e8e\u80bf\u7624\u574f\u6b7b\u56e0\u5b50\u03b1\u7684\u5168\u4eba\u6e90IgG1\u578b\u7684\u963f\u8fbe\u6728\u5355\u6297\u7684\u751f\u7269\u7c7b\u4f3c\u836f\uff0c\u88ab\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u7c7b\u98ce\u6e7f\u6027\u5173\u8282\u708e\uff0c\u5f3a\u76f4\u6027\u810a\u67f1\u708e\uff0c\u94f6\u5c51\u75c5\u5173\u8282\u708e\uff0c\u725b\u76ae\u7663\uff0c\u5316\u8113\u6027\u6c57\u817a\u708e\uff0c\u514b\u7f57\u6069\u75c5\uff0c\u6e83\u75a1\u6027\u7ed3\u80a0\u708e\uff0c\u8461\u8404\u819c\u708e\uff0c\u5e7c\u5e74\u578b\u7c7b\u98ce\u6e7f\u6027\u5173\u8282\u708e\u548c\u6591\u5757\u72b6\u94f6\u5c51\u75c5\u3002<\/p>\n

       <\/p>\n

6. Adalimumab biosimilar<\/strong><\/span><\/p>\n

       <\/p>\n

Hefiya\u00ae \u662f\u963f\u8fbe\u6728\u5355\u6297\uff08Adalimumab\uff09\u7684\u751f\u7269\u7c7b\u4f3c\u836f\uff0c\u4e8e2018\u5e747\u670826\u65e5\u83b7EMA\u6279\u51c6\u4e0a\u5e02\uff0c\u7531\u5c71\u5fb7\u58eb\u516c\u53f8\u7814\u53d1\u5e76\u8d1f\u8d23\u4e0a\u5e02\uff0c\u662f\u4e00\u79cd\u80bf\u7624\u574f\u6b7b\u56e0\u5b50\u03b1\uff08TNF\u03b1\uff09\u6291\u5236\u5242\uff0c\u88ab\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u810a\u67f1\u5173\u8282\u708e\u3001\u8461\u8404\u819c\u708e\u3001\u5316\u8113\u6027\u6c57\u817a\u708e\u3001\u94f6\u5c51\u75c5\u3001\u5e7c\u5e74\u7279\u53d1\u6027\u5173\u8282\u708e\u3001\u94f6\u5c51\u75c5\u5173\u8282\u708e\u3001\u4e18\u75b9\u9cde\u72b6\u76ae\u80a4\u75c5\u3001\u514b\u7f57\u6069\u6c0f\u75c5\u3001\u6e83\u75a1\u6027\u7ed3\u80a0\u708e\u548c\u513f\u7ae5\u6591\u5757\u72b6\u94f6\u5c51\u75c5\u3002<\/p>\n

       <\/p>\n

7. Romosozumab<\/strong><\/span><\/p>\n

       <\/p>\n

Romosozumab\u5df2\u4e8e2018\u5e741\u6708\u83b7EMA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3aEvenity\u00ae<\/p>\n

       <\/p>\n

\u662f\u4e00\u79cd\u9776\u5411\u4e8e\u786c\u5316\u86cb\u767d\u7684\u5355\u514b\u9686\u6297\u4f53\uff0c\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u9ad8\u9aa8\u6298\u98ce\u9669\u7edd\u7ecf\u5987\u5973\u548c\u9ad8\u9aa8\u6298\u98ce\u9669\u7537\u6027\u7684\u9aa8\u8d28\u758f\u677e\u75c7\u3002<\/p>\n

       <\/p>\n

8. Andexanet alfa<\/strong><\/span><\/p>\n

       <\/p>\n

Portola\u5236\u836f\u5f00\u53d1\u7684Andexanet alfa\u5df2\u4e8e2018\u5e745\u67083\u65e5\u83b7\u5f97FDA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3aAndexxa\u00ae\u3002\u662f\u4e00\u79cd\u91cd\u7ec4\u4fee\u9970\u7684\u51dd\u8840\u56e0\u5b50Xa\uff0c\u53ef\u7ed3\u5408\u51dd\u8840\u56e0\u5b50Xa\u6291\u5236\u5242\u5229\u4f10\u6c99\u73ed\u548c\u963f\u54cc\u6c99\u73ed\uff0c\u4ece\u800c\u53d1\u6325\u4fc3\u51dd\u8840\u4f5c\u7528\u3002\u8be5\u836f\u6279\u51c6\u7528\u4e8e\u7528\u5229\u4f10\u6c99\u73ed\u548c\u963f\u54cc\u6c99\u73ed\u6cbb\u7597\u7684\u60a3\u8005\u4e2d\u53d1\u751f\u5371\u53ca\u751f\u547d\u6216\u4e0d\u53ef\u63a7\u7684\u51fa\u8840\u7684\u9006\u8f6c\u6297\u51dd\u6cbb\u7597\u3002<\/p>\n

       <\/p>\n

9. Pegvaliase-pqpz<\/strong><\/span><\/p>\n

       <\/p>\n

Pegvaliase-pqpz\u5df2\u4e8e2018\u5e745\u670824\u65e5\u83b7FDA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3aPalynziq\u00ae\uff0c\u662f\u4e00\u79cd\u91cd\u7ec4\u7684\u82ef\u4e19\u6c28\u9178\u4ee3\u8c22\u9176\uff0c\u7531\u91cd\u7ec4\u82ef\u4e19\u6c28\u9178\u6c28\u57fa\u88c2\u89e3\u9176\u4e0eN-\u7f9f\u57fa\u7425\u73c0\u9170\u4e9a\u80fa\uff08NHS\uff09-\u7532\u6c27\u57fa\u805a\u4e59\u4e8c\u9187\uff08PEG\uff09\u5076\u8054\u800c\u6210\uff0c\u80fd\u5c06\u82ef\u4e19\u6c28\u9178\u8f6c\u5316\u4e3a\u6c28\u548c\u53cd\u5f0f\u8089\u6842\u9178\u3002\u8be5\u4ea7\u54c1\u7528\u4e8e\u964d\u4f4e\u82ef\u4e19\u916e\u5c3f\u75c7\u60a3\u8005\uff08\u8840\u6db2\u82ef\u4e19\u6c28\u9178\u6d53\u5ea6\u8d85\u8fc7600 \u03bcmol\/L\uff09\u7684\u8840\u6db2\u82ef\u4e19\u6c28\u9178\u6d53\u5ea6\u3002<\/p>\n

       <\/p>\n

10. Cemiplimab<\/strong><\/span><\/p>\n

       <\/p>\n

Cemiplimab\u4e8e2018\u5e749\u670828\u65e5\u83b7FDA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3aLibtayo\u00ae\uff0c\u662f\u4e00\u79cdPD-1\u7684\u5355\u514b\u9686\u6297\u4f53\uff0c\u88ab\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u8f6c\u79fb\u6027\u76ae\u80a4\u9cde\u72b6\u7ec6\u80de\u764c\uff08CSCC\uff09\u6216\u4e0d\u80fd\u63a5\u53d7\u6cbb\u6108\u6027\u624b\u672f\u6216\u653e\u7597\u7684\u5c40\u90e8\u665a\u671fCSCC\u60a3\u8005\u3002<\/p>\n

       <\/p>\n

11. Sintilimab\u4fe1\u8fea\u5229\u5355\u6297<\/strong><\/span><\/p>\n

       <\/p>\n

\u4fe1\u8fea\u5229\u5355\u6297\uff08IBI-308\uff09\u662f\u4fe1\u8fbe\u751f\u7269\u5f00\u53d1\u7684\u4e00\u79cdPD-1\uff0c\u7528\u4e8e\u81f3\u5c11\u7ecf\u8fc7\u4e8c\u7ebf\u7cfb\u7edf\u5316\u7597\u7684\u590d\u53d1\u6216\u96be\u6cbb\u6027\u7ecf\u5178\u578b\u970d\u5947\u91d1\u6dcb\u5df4\u7624\u7684\u6cbb\u7597\u4e8e2018\u5e7412\u670827\u65e5\u83b7NMPA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3a\u8fbe\u4f2f\u8212\u00ae\uff08Tyvyt\u00ae\uff09\uff0c\u6b64\u5916\uff0c\u6cbb\u7597\u665a\u671f\u7684\u6216\u8f6c\u79fb\u6027\u9cde\u72b6\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3001\u80c3\u53ca\u80c3\u98df\u7ba1\u4ea4\u754c\u5904\u817a\u764c\u7684\u7814\u7a76\uff0c\u73b0\u5904\u4e8e\u4e34\u5e8aIII\u671f\u3002<\/p>\n

       <\/p>\n

12. Toripalimab<\/strong><\/span><\/p>\n

       <\/p>\n

\u7279\u745e\u666e\u5229\u5355\u6297\uff08JS001) \u5546\u54c1\u540d\u4e3a\u62d3\u76ca\u00ae\uff0c2018\u5e7412\u670817\u65e5\u7279\u745e\u666e\u5229\u5355\u6297\u6ce8\u5c04\u6db2\u7684\u4e0a\u5e02\u7533\u8bf7\u83b7\u5f97NMPA\u6279\u51c6\u6210\u4e3a\u9996\u4e2a\u5728\u4e2d\u56fd\u4e0a\u5e02\u7684\u4e2d\u56fd\u81ea\u4e3b\u7814\u53d1\u7684PD-1\u5355\u6297\u3002\u662f\u4e0a\u6d77\u541b\u5b9e\u751f\u7269\u533b\u836f\u79d1\u6280\u80a1\u4efd\u6709\u9650\u516c\u548c\u82cf\u5dde\u4f17\u5408\u751f\u7269\u533b\u836f\u79d1\u6280\u6709\u9650\u516c\u53f8\uff08\u541b\u5b9e\u751f\u7269\u5b50\u516c\u53f8\uff09\u5f00\u53d1\u7684\u4e00\u79cd\u4eba\u6e90\u5316\u5355\u514b\u9686\u6297\u4f53\uff0c\u9776\u5411\u4e8e\u7a0b\u5e8f\u6027\u6b7b\u4ea1\u53d7\u4f531\uff08PD-1\uff09\uff0c\u7528\u4e8e\u6cbb\u7597\u65e2\u5f80\u63a5\u53d7\u5168\u8eab\u7cfb\u7edf\u6cbb\u7597\u5931\u8d25\u540e\u7684\u4e0d\u53ef\u5207\u9664\u6216\u8f6c\u79fb\u6027\u9ed1\u8272\u7d20\u7624\u60a3\u8005\uff0c\u62df\u7528\u4e8e\u6cbb\u7597\u4e73\u817a\u764c\u3001\u6dcb\u5df4\u7624\u3001\u6076\u6027\u9ed1\u8272\u7d20\u7624\u3001\u6ccc\u5c3f\u751f\u6b96\u7cfb\u7edf\u764c\u75c7\u548c\u5176\u5b83\u79cd\u7c7b\u5b9e\u4f53\u7624\uff0c<\/p>\n

       <\/p>\n

13. Velmanase alfa<\/strong><\/span><\/p>\n

       <\/p>\n

Zymenex\uff08Chiesi Farmaceutici\u7684\u5b50\u516c\u53f8\uff09\u7814\u53d1\u7684Velmanase alfa\u4e8e2018\u5e743\u670823\u65e5\u83b7EMA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3aLamzede\u00ae\uff0c\u662f\u4e00\u79cd\u91cd\u7ec4\u03b1-\u7518\u9732\u7cd6\u82f7\u9176\uff0c\u53ef\u8865\u5145\u6216\u66ff\u4ee3\u5929\u7136\u03b1-\u7518\u9732\u7cd6\u82f7\u9176\uff0c\u4ee5\u51cf\u5c11\u7518\u9732\u7cd6\u7684\u8d2e\u79ef\u3002\u8be5\u836f\u88ab\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u8f7b\u5ea6\u81f3\u4e2d\u5ea6\u03b1\u7518\u9732\u7cd6\u82f7\u8d2e\u79ef\u75c7\u3002<\/p>\n

       <\/p>\n

14. Lanadelumab<\/strong><\/span><\/p>\n

       <\/p>\n

Lanadelumab\u4e8e2018\u5e748\u670823\u65e5\u83b7FDA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3aTakhzyro\u00ae\uff0c\u662f\u4e00\u79cd\u9776\u5411\u4e8e\u8840\u6d46\u6fc0\u80bd\u91ca\u653e\u9176\uff08pKal\uff09\u7684\u4eba\u6e90\u6027\u5355\u514b\u9686IgG1\u6297\u4f53\uff0c\u7528\u4e8e\u9884\u963212\u5c81\u53ca\u4ee5\u4e0a\u9057\u4f20\u6027\u8840\u7ba1\u6027\u6c34\u80bf\uff08HAE\uff09\u60a3\u8005\u7684\u8840\u7ba1\u6027\u6c34\u80bf\u53d1\u4f5c\u3002<\/p>\n

       <\/p>\n

15. Meningococcal A\/C vaccine<\/strong><\/span><\/p>\n

       <\/p>\n

\u534e\u5170\u751f\u7269\u75ab\u82d7\u7814\u53d1\u7684A\u7fa4\u53caC\u7fa4\u8111\u819c\u708e\u7403\u83cc\u75ab\u82d7\uff08Meningococcal A\/C vaccine\uff09\u4e8e2018\u5e743\u670820\u65e5\u83b7NMPA\u6279\u51c6\u4e0a\u5e02\u3002A\u7fa4\u53caC\u7fa4\u8111\u819c\u708e\u7403\u83cc\u75ab\u82d7\u88ab\u6279\u51c6\u7528\u4e8e\u9884\u9632A\u7fa4\u53caC\u7fa4\u8111\u819c\u708e\u7403\u83cc\u5f15\u8d77\u7684\u6d41\u884c\u6027\u8111\u810a\u9ad3\u819c\u708e\u3002<\/p>\n

       <\/p>\n

16. House-dust mite allergy immunotherapy<\/strong><\/span><\/p>\n

       <\/p>\n

\u7531Lofarma\u7814\u53d1\u7684\u5c4b\u5c18\u87a8\u8fc7\u654f\u514d\u75ab\u7597\u6cd5\uff0c\u4e8e2018\u5e74\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3aLAIS Mites Sublingual tablets\u00ae\uff0c\u662f\u4e00\u79cd\u514d\u75ab\u7597\u6cd5\uff0c\u88ab\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u8fc7\u654f\u6027\u54ee\u5598\u3001\u9f3b\u708e\u548c\u9f3b\u7ed3\u819c\u708e<\/p>\n

       <\/p>\n

17. tagraxofusp-erzs<\/strong><\/span><\/p>\n

       <\/p>\n

Tagraxofusp-erzs\u4e8e2018\u5e7412\u6708\u83b7FDA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3aElzonris\u00ae\u3002\u6b64\u836f\u662f\u4e00\u79cd\u9776\u5411CD123\u7684\u7ec6\u80de\u6bd2\u7d20\uff0c\u662f\u7531\u767d\u4ecb\u7d20-3\u548c\u767d\u5589\u6bd2\u7d20\u90e8\u5206\u7247\u6bb5\u5f62\u6210\u7684\u91cd\u7ec4\u878d\u5408\u86cb\u767d\u3002\u8be5\u836f\u88ab\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u6025\u6027\u6d46\u7ec6\u80de\u6837\u6811\u7a81\u72b6\u7ec6\u80de\u7624\uff08BPDCN\uff09\u7684\u6210\u4eba\u53ca2\u5c81\u4ee5\u4e0a\u7684\u513f\u7ae5\u60a3\u8005\u3002<\/p>\n

       <\/p>\n

18. Tildrakizumab-asmn<\/strong><\/span><\/p>\n

       <\/p>\n

Tildrakizumab-asmn\u4e8e2018\u5e743\u670820\u65e5\u83b7FDA\u6279\u51c6\u4e0a\u5e02\uff0c\u540e\u4e8e2018\u5e749\u670817\u65e5\u83b7EMA\u6279\u51c6\u4e0a\u5e02\uff0cIlumya\u00ae\uff0c\u662f\u4e00\u79cd\u4eba\u6e90\u5316IgG1\u03ba\u578b\u5355\u514b\u9686\u6297\u4f53\uff0c\u9776\u5411\u4e8e\u767d\u7ec6\u80de\u4ecb\u7d2023\uff08IL-23\uff09\u7684p19\u4e9a\u57fa\uff0c\u80fd\u963b\u65adp19\u4e9a\u57fa\u4e0e\u767d\u7ec6\u80de\u4ecb\u7d2023\uff08IL-23\uff09\u53d7\u4f53\u7684\u76f8\u4e92\u4f5c\u7528\u3002\u8be5\u836f\u88ab\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u6210\u4eba\u4e2d\u81f3\u91cd\u5ea6\u6591\u5757\u72b6\u94f6\u5c51\u75c5\u3002<\/p>\n

       <\/p>\n

19. Emapalumab<\/strong><\/span><\/p>\n

       <\/p>\n

Emapalumab\u5355\u6297\u5df2\u7ecf\u4e8e2018\u5e7411\u670820\u65e5\u83b7\u5f97FDA\u7684\u4e0a\u5e02\u6279\u51c6\u3002\u8be5\u836f\u7531Novimmune SA\u7814\u53d1\u3001\u9500\u552e\uff0c\u5546\u54c1\u540d\u4e3aGamifant\u00ae\uff0c\u662f\u4e00\u79cd\u9776\u5411\u5e72\u6270\u7d20-\u03b3\uff08IFN-\u03b3\uff09\u7684\u5168\u4eba\u6e90\u5355\u6297\uff0c\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u539f\u53d1\u6027\u55dc\u8840\u7ec6\u80de\u6027\u6dcb\u5df4\u7ec4\u7ec7\u7ec6\u80de\u589e\u591a\u75c7\uff08HLH\uff09\u7684\u6210\u4eba\u6216\u5a74\u5e7c\u513f\u60a3\u8005\u3002<\/p>\n

       <\/p>\n

20. Recombinant cytokine gene derived protein<\/strong><\/span><\/p>\n

       <\/p>\n

\u6b64\u54c1\u7531\u6770\u534e\u751f\u7269\u5f00\u53d1\uff0c\u5df2\u4e8e2018\u5e744\u670812\u65e5\u83b7\u5f97NMPA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e50\u590d\u80fd\u00ae\uff0c\u662f\u4e00\u79cd\u91cd\u7ec4\u7ec6\u80de\u56e0\u5b50\u57fa\u56e0\u884d\u751f\u86cb\u767d\uff0c\u5176\u7ed3\u6784\u4e0e\u5e8f\u5217\u5929\u7136\u7684\u5e72\u6270\u7d20\u6709\u5f88\u5927\u4e0d\u540c\uff0c\u53ef\u6291\u5236\u75c5\u6bd2\u590d\u5236\uff0c\u589e\u5f3a\u6297\u75c5\u6bd2\u514d\u75ab\uff0c\u540c\u65f6\u4e5f\u53ef\u589e\u5f3a\u81ea\u8eab\u514d\u75ab\u529b\u5e76\u6291\u5236\u80bf\u7624\u7ec6\u80de\u589e\u6b96\u3001\u80bf\u7624\u8840\u7ba1\u751f\u957f\uff0c\u4ee5\u963b\u65ad\u80bf\u7624\u8840\u6db2\u4f9b\u5e94\uff0c\u7528\u4e8e\u6cbb\u7597\u6162\u6027\u4e59\u578b\u809d\u708e\u3002<\/p>\n

       <\/p>\n

21. Trastuzumab biosimilar<\/strong><\/span><\/p>\n

       <\/p>\n

Kanjinti\u00ae\u5df2\u4e8e2018\u5e745\u670816\u65e5\u83b7EMA\u6279\u51c6\u4e0a\u5e02\uff0c\u4e8e2018\u5e749\u670821\u65e5\u83b7PMDA\u6279\u51c6\u4e0a\u5e02\u3002\u8be5\u4ea7\u54c1\u662f\u66f2\u59a5\u73e0\u5355\u6297\uff08Trastuzumab\uff09\u7684\u751f\u7269\u7c7b\u4f3c\u836f\uff0c\u5373\u4e00\u79cd\u9776\u5411\u4e8eHER2\u7684\u4eba\u6e90\u5316IgG1\u5355\u514b\u9686\u6297\u4f53\uff0c\u7528\u4e8e\u6cbb\u7597HER2+\u65e9\u671f\u4e73\u817a\u764c\u548c\u80c3\u764c\u3002<\/p>\n

       <\/p>\n

22. Trastuzumab biosimilar<\/strong><\/span><\/p>\n

       <\/p>\n

Trazimera\u00ae\u662f\u66f2\u59a5\u73e0\u5355\u6297\u7684\u751f\u7269\u7c7b\u4f3c\u7269\uff0c\u7531Pfizer\u516c\u53f8\u7814\u53d1\uff0c\u4e8e2018\u5e747\u670826\u65e5\u83b7EMA\u6279\u51c6\u4e0a\u5e02\uff0c\u662f\u4e00\u79cd\u4eba\u6e90\u5316IgG1\u578b\u5355\u514b\u9686\u6297\u4f53\uff0c\u5176\u4e0e\u80bf\u7624\u7ec6\u80de\u4e0a\u7684HER2\u7ed3\u5408\u5e76\u4ecb\u5bfc\u6297\u4f53\u4f9d\u8d56\u7684\u7ec6\u80de\u6bd2\u4f5c\u7528\uff08ADCC\uff09\u3002\u8be5\u836f\u7528\u4e8e\u6cbb\u7597HER2\u8fc7\u8868\u8fbe\u7684\u4e73\u817a\u764c\u60a3\u3001HER2\u8fc7\u8868\u8fbe\u7684\u8f6c\u79fb\u6027\u80c3\u764c\u6216\u98df\u7ba1\u80c3\u4ea4\u754c\u817a\u764c\u3002<\/p>\n

       <\/p>\n

23. Agalsidase beta biosimilar<\/strong><\/span><\/p>\n

       <\/p>\n

JCR Pharmaceuticals\u5f00\u53d1\u7684\u963f\u52a0\u7cd6\u9176\u03b2\u751f\u7269\u4eff\u5236\u836f\u4e8e2018\u5e749\u670821\u83b7PMDA\u6279\u51c6\u4e0a\u5e02\u3002\u963f\u52a0\u7cd6\u9176\u03b2\u662f\u4e00\u79cd\u91cd\u7ec4\u534a\u4e73\u7cd6\u82f7\u9176\u03b1\uff0c\u88ab\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u6cd5\u5e03\u91cc\u75c5\u3002<\/p>\n

       <\/p>\n

24. Condoliase<\/strong><\/span><\/p>\n

       <\/p>\n

Condoliase\u7531\u751f\u5316\u5b66\u5de5\u4e1a\u682a\u5f0f\u4f1a\u793e\u7814\u53d1\uff0c\u4e8e2018\u5e743\u6708\u83b7PMDA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3aHernicore\u00ae\u3002\u662f\u4e00\u79cd\u7cd6\u80fa\u805a\u7cd6\u964d\u89e3\u9176\uff0c\u53ef\u4ee5\u8bf1\u5bfc\u690e\u95f4\u76d8\u7ec4\u7ec7\u7684\u8f6f\u9aa8\u7d20-6\u786b\u9178\u86cb\u767d\u805a\u7cd6\u6eb6\u89e3\u3002\u8be5\u4ea7\u54c1\u88ab\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u690e\u95f4\u76d8\u79fb\u4f4d\u3002<\/p>\n

       <\/p>\n

25. Burosumab-twza<\/strong><\/span><\/p>\n

       <\/p>\n

\u7531Kyowa Hakko Kirin\u539f\u7814\u7684Burosumab-twza\u5df2\u4e8e2018\u5e742\u670819\u65e5\u83b7EMA\u6279\u51c6\uff0c2018\u5e744\u670817\u65e5\u83b7FDA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3aCrysvita\u00ae\uff0c\u662f\u4e00\u79cd\u5168\u4eba\u6e90IgG1\u578b\u5355\u514b\u9686\u6297\u4f53\uff0c\u9776\u5411\u4e8e\u6210\u7ea4\u7ef4\u7ec6\u80de\u751f\u957f\u56e0\u5b5023\uff08FGF23\uff09\uff0c\u6279\u51c6\u7528\u4e8e\u6cbb\u7597X\u8fde\u9501\u4f4e\u78f7\u9178\u76d0\u8840\u75c7\uff08XLH\uff09\u3002\u8fd9\u662f\u9996\u4e2a\u83b7\u6279\u6cbb\u75971\u5c81\u53ca\u4ee5\u4e0a\u513f\u7ae5\u548c\u6210\u5e74\u4eba\u7684X\u8fde\u9501\u4f4e\u78f7\u8840\u75c7\uff08XLH\uff09\u7684\u5b64\u513f\u836f\u3002<\/p>\n

       <\/p>\n

26. Damoctocog alfa pegol<\/strong><\/span><\/p>\n

       <\/p>\n

Jivi\u00ae\uff08Damoctocog alfa pegol\uff09\u662fBayer\u7814\u53d1\u7684\u4e00\u79cd\u805a\u4e8c\u4e59\u9187\u5316\u7684\u91cd\u7ec4\u4eba\u51dd\u8840\u56e0\u5b50VIII\uff0c\u4e8e2018\u5e748\u670829\u65e5\u83b7FDA\u6279\u51c6\u4e0a\u5e02\u3002Jivi\u00ae\u662f\u4e00\u79cd\u91cd\u7ec4\u56e0\u5b50VIII\uff08rFVIII\uff09\u66ff\u4ee3\u7597\u6cd5\uff0c\u53ef\u66ff\u4ee3\u51dd\u8840\u8fc7\u7a0b\u4e2d\u7f3a\u5931\u7684\u51dd\u8840\u56e0\u5b50VIII\u3002Jivi\u00ae\u83b7\u6279\u9002\u7528\u4e8e\u5148\u524d\u6cbb\u7597\u7684\u6210\u4eba\u548c\u9752\u5c11\u5e74\uff0812\u5c81\u53ca\u4ee5\u4e0a\uff09\u7684\u8840\u53cb\u75c5A\u60a3\u8005\uff0c\u7528\u4e8e\u6309\u9700\u6cbb\u7597\u548c\u63a7\u5236\u51fa\u8840\u4e8b\u4ef6\uff1b\u56f4\u624b\u672f\u671f\u51fa\u8840\uff1b\u5e38\u89c4\u9884\u9632\u4ee5\u51cf\u5c11\u51fa\u8840\u53d1\u4f5c\u7684\u9891\u7387\u3002<\/p>\n

       <\/p>\n

27. Mecapegfilgrastim<\/strong><\/span><\/p>\n

       <\/p>\n

\u6c5f\u82cf\u6052\u745e\u5f00\u53d1\u7684\u786b\u57f9\u975e\u683c\u53f8\u4ead\u5df2\u4e8e2018\u5e745\u67088\u65e5\u83b7\u5f97NMPA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3a\u827e\u591a\u00ae\u3002\u8be5\u4ea7\u54c1\u662f\u4e00\u79cd\u805a\u4e59\u4e8c\u9187\u5316\u91cd\u7ec4\u7c92\u7ec6\u80de\u96c6\u843d\u523a\u6fc0\u56e0\u5b50\uff0c\u7528\u4e8e\u5316\u7597\u5f15\u8d77\u7684\u4e2d\u6027\u7c92\u7ec6\u80de\u51cf\u5c11\u75c7\u3002<\/p>\n

       <\/p>\n

28. Pegfilgrastim biosimilar (Cinfa Biotech)<\/strong><\/span><\/p>\n

       <\/p>\n

\u57f9\u975e\u683c\u53f8\u4ead\u751f\u7269\u4eff\u5236\u836f\uff08Cinfa Biotech\uff09\u4e8e2018\u5e7411\u670820\u65e5\u901a\u8fc7EMA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3aPelmeg\u00ae\uff0c\u662f\u4e00\u79cd\u76ae\u4e0b\u6ce8\u5c04\u7684\u6eb6\u6db2\uff0c\u6d3b\u6027\u6210\u5206\u4e3a\u805a\u4e59\u4e8c\u9187\u5316\u91cd\u7ec4\u7c92\u7ec6\u80de\u96c6\u843d\u523a\u6fc0\u56e0\u5b50\uff0c\u7528\u4e8e\u6cbb\u7597\u5316\u7597\u5f15\u8d77\u7684\u4e2d\u6027\u7c92\u7ec6\u80de\u51cf\u5c11\u75c7\uff0c\u5e76\u53ef\u9884\u9632\u53d1\u70ed\u6027\u4e2d\u6027\u7c92\u7ec6\u80de\u51cf\u5c11\u75c7\u3002<\/p>\n

       <\/p>\n

29. Pegfilgrastim biosimilar<\/strong><\/span><\/p>\n

       <\/p>\n

Zioxtenzo\u00ae\u662f\u8bfa\u534e\u7684\u5b50\u516c\u53f8\u5c71\u5fb7\u58eb\u7814\u53d1\u7684pegfilgrastim\u751f\u7269\u7c7b\u4f3c\u836f\u3002\u6b64\u836f\u4e8e2018\u5e7412\u6708\u5728\u82f1\u56fd\u83b7\u6279\u4e0a\u5e02\uff0c\u662f\u4e00\u79cd\u805a\u4e59\u4e8c\u9187\u5316\u7684\u91cd\u7ec4\u4eba\u7c92\u7ec6\u80de\u96c6\u843d\u523a\u6fc0\u56e0\u5b50\uff0c\u80fd\u8c03\u8282\u9aa8\u9ad3\u4e2d\u6027\u7c92\u7ec6\u80de\u7684\u4ea7\u751f\uff0c\u5e76\u5f71\u54cd\u4e2d\u6027\u7c92\u7ec6\u80de\u524d\u4f53\u7684\u589e\u6b96\u3001\u5206\u5316\u548c\u529f\u80fd\u3002\u8be5\u836f\u7528\u4e8e\u6cbb\u7597\u975e\u9ad3\u6027\u6076\u6027\u80bf\u7624\u60a3\u8005\u53d1\u70ed\u6027\u4e2d\u6027\u7c92\u7ec6\u80de\u51cf\u5c11\u75c7\u3002<\/p>\n

       <\/p>\n

30. Pegfilgrastim-cbqv<\/strong><\/span><\/p>\n

       <\/p>\n

Pegfilgrastim-cbqv\u7531Coherus Biosciences\u7814\u53d1\uff0c\u4e8e2018\u5e7411\u67082\u65e5\u83b7FDA\u6279\u51c6\u4e0a\u5e02\uff0c\u540e\u4e8e2018\u5e749\u670821\u65e5\u83b7EMA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3aUdenyca\u00ae\uff0c\u662f\u4e00\u79cd\u805a\u4e59\u4e8c\u9187\u5316\u91cd\u7ec4\u7c92\u7ec6\u80de\u96c6\u843d\u523a\u6fc0\u56e0\u5b50\uff0c\u7528\u4e8e\u6cbb\u7597\u5316\u7597\u5f15\u8d77\u7684\u4e2d\u6027\u7c92\u7ec6\u80de\u51cf\u5c11\u75c7\u3002<\/p>\n

       <\/p>\n

31. Pegfilgrastim-jmdb<\/strong><\/span><\/p>\n

       <\/p>\n

Pegfilgrastim-jmdb\u5df2\u4e8e2018\u5e746\u67084\u65e5\u83b7FDA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3aFulphila\u00ae\u3002<\/p>\n

       <\/p>\n

Pegfilgrastim-jmdb\u662fPegfilgrastim\u7684\u751f\u7269\u7c7b\u4f3c\u836f\uff0c\u5373\u4e00\u79cd\u91cd\u7ec4\u7532\u786b\u6c28\u9170\u4eba\u7c92\u7ec6\u80de\u96c6\u843d\u523a\u6fc0\u56e0\u5b50\uff08G-CSF\uff09\u548c\u5355\u7532\u6c27\u57fa\u805a\u4e59\u4e8c\u9187\u7684\u5171\u4ef7\u7f00\u5408\u7269\u3002\u8be5\u4ea7\u54c1\u7528\u4e8e\u6cbb\u7597\u9aa8\u9ad3\u6291\u5236\u6027\u6297\u764c\u836f\u5f15\u8d77\u7684\u53d1\u70ed\u6027\u4e2d\u6027\u7c92\u7ec6\u80de\u51cf\u5c11\u75c7\u3002<\/p>\n

       <\/p>\n

32. Fremanezumab<\/strong><\/span><\/p>\n

       <\/p>\n

Fremanezumab\u4e8e2018\u5e749\u670814\u65e5\u83b7FDA\u6279\u51c6\u4e0a\u5e02, \u5546\u54c1\u540d\u4e3aAjovy\u00ae\uff0c\u662f\u4e00\u79cd\u9776\u5411\u4e8e\u964d\u9499\u7d20\u57fa\u56e0\u76f8\u5173\u80bd\uff08CGRP\uff09\u7684\u4eba\u6e90\u5316IgG2\u03ba\u578b\u5355\u514b\u9686\u6297\u4f53\uff0c\u88ab\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u6210\u4eba\u504f\u5934\u75db\u3002<\/p>\n

       <\/p>\n

33. Galcanezumab<\/strong><\/span><\/p>\n

       <\/p>\n

Galcanezumab\u7531Lili\u516c\u53f8\u7814\u53d1\uff0c\u4e8e2018\u5e749\u670827\u65e5\u83b7FDA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3aEmgality\u00ae\uff0c\u662f\u4e00\u79cd\u4eba\u6e90\u5316\u5355\u514b\u9686\u6297\u4f53\uff0c\u9776\u5411\u4e8e\u964d\u9499\u7d20\u57fa\u56e0\u76f8\u5173\u80bd\uff08CGRP\uff09\uff0c\u88ab\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u6210\u4eba\u60a3\u8005\u504f\u5934\u75db\u3002<\/p>\n

       <\/p>\n

34. Ibalizumab-uiyk<\/strong><\/span><\/p>\n

       <\/p>\n

Ibalizumab-uiyk 2018\u5e743\u67086\u65e5\u9996\u6b21\u88abFDA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3aTrogarzo\u00ae\uff0c\u662f\u4e00\u79cd\u4eba\u6e90\u5316IgG4\u578b\u5355\u514b\u9686\u6297\u4f53\uff0c\u5176\u901a\u8fc7\u7ed3\u5408CD4\u7684\u7ed3\u6784\u57df2\uff0c\u5e72\u6270HIV-1\u4fb5\u5165\u5bbf\u4e3b\u7ec6\u80de\u7684\u8fc7\u7a0b\uff0c\u6765\u963b\u6b62HIV-1\u611f\u67d3CD4+T\u7ec6\u80de\u3002\u8be5\u836f\u6279\u51c6\u7684\u9002\u5e94\u75c7\u4e3a\u6210\u4ebaHIV-1\u75c5\u6bd2\u611f\u67d3\uff0c\u5305\u62ec\u66fe\u63a5\u53d7\u591a\u79cd\u6297HIV-1\u65b9\u6848\uff0c\u5bf9\u5176\u5b83\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2 \u836f\u7269\u6709\u6297\u836f\u6027\u548c\u76ee\u524d\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u7597\u6cd5\u5931\u8d25\u7684\u60a3\u8005\u3002<\/p>\n

       <\/p>\n

35. Moxetumomab pasudotox<\/strong><\/span><\/p>\n

       <\/p>\n

Moxetumomab pasudotox\u7531AZ\u516c\u53f8\u7814\u53d1\uff0c\u4e8e2018\u5e749\u670813\u65e5\u83b7FDA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3aLumoxiti\u00ae\uff0c\u662f\u4e00\u79cd\u91cd\u7ec4\u7684\u9776\u5411\u4e8eCD22\u7684\u6297\u6bd2\u7d20\uff0c\u88ab\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u6bdb\u7ec6\u80de\u767d\u8840\u75c5\u7684\u3002<\/p>\n

       <\/p>\n

36. Erenumab-aooe<\/strong><\/span><\/p>\n

       <\/p>\n

Erenumab-aooe\u5df2\u4e8e2018\u5e745\u670817\u65e5\u83b7FDA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3aAimovig\u00ae\uff0c\u662f\u4e00\u79cd\u5168\u4eba\u6e90IgG2\u578b\u5355\u514b\u9686\u6297\u4f53\uff0c\u9776\u5411\u4e8e\u964d\u9499\u7d20\u57fa\u56e0\u76f8\u5173\u80bd\uff08CGRP\uff09\u53d7\u4f53\u3002\u8be5\u836f\u6279\u51c6\u7528\u4e8e\u9884\u9632\u548c\u6cbb\u7597\u6210\u4eba\u504f\u5934\u75db\u3002<\/p>\n

       <\/p>\n

37. Ravulizumab<\/strong><\/span><\/p>\n

       <\/p>\n

\u7531Alexion Pharma\u7814\u53d1\u7684Ravulizumab\u4e8e2018\u5e7412\u670821\u65e5\u83b7FDA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3a Ultomiris\u00ae\uff0c\u662f\u4e00\u79cd\u9776\u5411\u4e8e\u8865\u4f53\u86cb\u767dC5\u7684\u4eba\u6e90\u5316\u5355\u514b\u9686\u6297\u4f53\uff0c\u6cbb\u7597\u9635\u53d1\u6027\u7761\u7720\u6027\u8840\u7ea2\u86cb\u767d\u5c3f\u7684\u5b64\u513f\u836f\u3002<\/p>\n

       <\/p>\n

38. Calaspargase pegol<\/strong><\/span><\/p>\n

       <\/p>\n

Calaspargase pegol\u4e8e2018\u5e7412\u6708\u83b7FDA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3aAsparlas\u00ae\u3002\u8be5\u836f\u662f\u4e00\u79cd\u5929\u51ac\u9170\u80fa\u7279\u5f02\u6027\u9176\uff0c\u53ef\u4ee5\u50ac\u5316L-\u5929\u51ac\u9170\u80fa\u4e3a\u5929\u51ac\u6c28\u9178\u548c\u6c28\uff0c\u6279\u51c6\u7528\u4e8e\u9488\u5bf9\u5c0f\u513f\u548c\u6210\u4eba\u6dcb\u5df4\u7cfb\u767d\u8840\u75c5\u7684\u591a\u836f\u7269\u5316\u7597\u7684\u8f85\u52a9\u836f\u7269\u3002 Asparlas\u00ae\u7684\u836f\u7406\u4f5c\u7528\u662f\u57fa\u4e8e\u6e05\u9664\u8840\u6d46\u4e2d\u7684L-\u5929\u51ac\u9170\u80fa\uff0c\u8fdb\u800c\u6740\u4f24\u767d\u8840\u75c5\u7ec6\u80de\u3002<\/p>\n

       <\/p>\n

39. Elapegademase-lvlr<\/strong><\/span><\/p>\n

       <\/p>\n

Elapegademase-lvlr\u7531Leadiant Biosci\u7814\u53d1\uff0c\u4e8e2018\u5e7410\u67085\u65e5\u83b7FDA\u6279\u51c6\u4e0a\u5e02\uff0c\u5546\u54c1\u540d\u4e3aRevcovi\u00ae\uff0c\u662f\u4e00\u79cd\u91cd\u7ec4\u817a\u82f7\u8131\u6c28\u9176\uff0c\u7528\u4e8e\u6cbb\u7597\u513f\u7ae5\u548c\u6210\u4eba\u514d\u75ab\u7f3a\u9677\u75c5\u60a3\u8005\u7684ADA\u7f3a\u4e4f\u75c7\uff08ADA-SCID\uff09\u3002<\/p>\n

       <\/p>\n

\u751f\u7269\u836f\u7684\u53d1\u5c55\u5728\u6574\u4e2a\u533b\u836f\u884c\u4e1a\u5448\u73b0\u5feb\u901f\u4e0a\u5347\u8d8b\u52bf\uff0c\u8d8a\u6765\u8d8a\u591a\u7684\u516c\u53f8\u79ef\u6781\u6295\u5165\u5230\u751f\u7269\u836f\u7684\u7814\u7a76\u4e2d\u3002\u4f46\u540c\u65f6\u4e2d\u56fd\u7684\u751f\u7269\u7269\u521b\u65b0\u76f8\u6bd4\u4e8e\u6b27\u7f8e\u56fd\u5bb6\u8fd8\u8f83\u4e3a\u843d\u540e\uff0c\u56fd\u5185\u751f\u7269\u836f\u5e02\u573a\u7edd\u5927\u90e8\u5206\u4efd\u989d\u8fd8\u88ab\u5916\u8d44\u4f01\u4e1a\u4ea7\u54c1\u5360\u636e\u548c\u4e3b\u5bfc\u3002\u636eIMS Health\u9884\u8ba1\uff0c\u52302020\u5e74\uff0c\u6211\u56fd\u751f\u7269\u533b\u836f\u5e02\u573a\u5c06\u6210\u4e3a\u4ec5\u6b21\u4e8e\u7f8e\u56fd\u7684\u5168\u7403\u7b2c\u4e8c\u5927\u751f\u7269\u533b\u836f\u5e02\u573a\u3002\u90a3\u4e48\u5728\u8fd9\u4e2a\u8fc7\u7a0b\u4e2d\u98ce\u53e3\u5728\u54ea\uff1f\u6211\u4eec\u5982\u4f55\u624d\u80fd\u98de\u5f97\u66f4\u9ad8\uff1f\u4e0b\u56de\u5206\u89e3~<\/p>\n

       <\/p>\n


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\u4f5c\u8005\u7b80\u4ecb<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u7384\u836f<\/strong>\uff0c\u533b\u836f\u884c\u4e1a\u72ec\u7acb\u89c2\u5bdf\u8005\u3002\u4e2d\u56fd\u836f\u79d1\u5927\u5b66\u7855\u58eb\uff0c\u836f\u7406\u5b66\u4e13\u4e1a\u3002\u5148\u540e\u4efb\u804c\u4e8e\u56fd\u5185\u4e0a\u5e02\u836f\u4f01\u5e02\u573a\u90e8\u3001500\u5f3a\u5916\u4f01\u8425\u9500\u90e8\u3002\u73b0\u4ece\u4e8b\u533b\u836f\u79c1\u52df\u6295\u8d44\u884c\u4e1a\u3002<\/p>\n


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\u5fae\u4fe1\u53f7\uff1apharmacology_cpu       <\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section><\/div>\n","protected":false},"excerpt":{"rendered":"

\u8f6c\u8f7d\u81ea\uff1aCPhI\u5236\u836f\u5728\u7ebf \u76d8\u70b92018\u5168\u7403\u65b0\u4e0a\u5e02\u768439\u4e2a\u751f\u7269\u836f 21\u4e16\u7eaa\u662f\u751f\u547d\u79d1\u5b66\u7684\u4e16\u7eaa\uff0c\u5f53\u524d\u7f8e\u56fd\u79d1\u5b66\u9662\u6709\u8d85\u8fc7 […]<\/p>\n","protected":false},"author":1,"featured_media":78321,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/78320"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=78320"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/78320\/revisions"}],"predecessor-version":[{"id":78324,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/78320\/revisions\/78324"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/78321"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=78320"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=78320"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=78320"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}