{"id":78362,"date":"2018-12-20T00:00:50","date_gmt":"2019-02-01T06:16:27","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/78362\/"},"modified":"2019-02-01T14:16:30","modified_gmt":"2019-02-01T06:16:30","slug":"eddca1790a","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/78362\/","title":{"rendered":"\u4e0d\u8d70\u5bfb\u5e38\u8def\u7684\u751f\u7269\u79d1\u6280\u5de8\u5934\uff1a\u65b0\u57fa\u516c\u53f8\u63ed\u79d8"},"content":{"rendered":"
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2018\u5e741\u670825\u65e5\uff0c\u65b0\u57fa\u516c\u5e032017\u5e74\u4e1a\u7ee9\uff0c\u5168\u5e74\u5b9e\u73b0\u603b\u8425\u6536130.03\u4ebf\u7f8e\u5143\uff0c\u540c\u6bd42016\u5e74\u589e\u957f15.8%\uff1b\u9884\u8ba1\u51762018\u5e74\u603b\u6536\u5165\u53ef\u8fbe144-148\u4ebf\u7f8e\u5143\u30022017\u5e74\u65b0\u57fa\u5728\u7814\u53d1\u4e0a\u6295\u516559.15\u4ebf\u7f8e\u5143\uff0c\u5360\u603b\u6536\u516545.5%\u3002<\/span><\/p>\n

\u65b0\u57fa\u516c\u53f8\u603b\u90e8\u8bbe\u5728\u7f8e\u56fd\u65b0\u6cfd\u897f\u5dde\u7684Summit\uff0c\u5168\u7403\u8fd0\u8425\u603b\u90e8\u53ca\u6b27\u6d32\u603b\u90e8\u8bbe\u5728\u745e\u58eb\u7684Boudry\uff0c\u4e9a\u592a\u5730\u533a\u603b\u90e8\u8bbe\u5728\u65b0\u52a0\u5761\uff08Newton\uff09\u5168\u7403\u5458\u5de5\u7ea67000\u4f59\u4eba\uff0c\u4e0b\u5c5e\u5b50\u516c\u53f8\u548c\u5206\u652f\u673a\u6784\u5df2\u6709\u4e8c\u5341\u591a\u5bb6\uff0c\u5305\u62ec\u4eca\u5e74\u5e74\u521d\u9ad8\u4ef7\u65b0\u6536\u8d2d\u7684Impact Biomedicines\u53ca\u6731\u8bfa\u516c\u53f8\uff08Juno Therapeutics\uff09\u90fd\u5df2\u7eb3\u5165\u65b0\u57fa\u7684\u7248\u56fe\u3002\u65b0\u57fa\u516c\u53f8\u6c38\u8fdc\u628a\u60a3\u8005\u653e\u5728\u7b2c\u4e00\u4f4d\uff0c\u516c\u53f8\u7684\u5b97\u65e8\u662f\u81f4\u529b\u4e8e\u5728\u5168\u7403\u8303\u56f4\u5185\u6539\u5584\u60a3\u8005\u7684\u751f\u6d3b\uff08Improving the lives of patients worldwide\uff09\u3002\u5168\u7403\u8d85\u8fc750\u4e2a\u56fd\u5bb6\u768452.5\u4e07\u60a3\u8005\u5728\u4f7f\u7528\u65b0\u57fa\u7684\u4ea7\u54c1\uff1b\u516c\u53f8\u73b0\u4efb\u8463\u4e8b\u4f1a\u4e3b\u5e2d\u517c\u9996\u5e2d\u6267\u884c\u5b98\u4e3aMark J. Alles\u3002\u516c\u53f8\u80a1\u4ef773.42\u7f8e\u5143\uff082018\u5e7412\u67083\u65e5\u6570\u636e\uff09\uff0c\u76ee\u524d\u603b\u5e02\u503c\u5df2\u8d85\u8fc7500\u4ebf\u7f8e\u5143\u3002<\/span><\/p>\n

\u516c\u53f8\u4ea7\u54c1<\/span><\/p>\n

\u65b0\u57fa\u516c\u53f8\u8fc7\u53bb\u51e0\u5e74\u7684\u4e1a\u7ee9\u4e3b\u8981\u6765\u81ea\u4e8e\u516c\u53f8\u76844\u6b3e\u836f\u7269\uff1a\u6765\u90a3\u5ea6\u80fa\uff08Lenalidomide, Revlimid\uff09\u3001\u6cca\u9a6c\u5ea6\u80fa\uff08Pomalidomide, Pomalyst\uff09\u3001\u963f\u666e\u65af\u7279\uff08Apremilast, Otezla\uff09\u548c\u767d\u86cb\u767d\u7ed3\u5408\u578b\u6ce8\u5c04\u7528\u7d2b\u6749\u9187\uff08Paclitaxel, Abraxane\uff09\uff0c\u8fd94\u6b3e\u836f\u7269\u5728\u672a\u6765\u5c06\u4f9d\u65e7\u4e3a\u516c\u53f8\u5e26\u6765\u826f\u597d\u6536\u5165\uff0c\u5c24\u5176\u662f\u6765\u90a3\u5ea6\u80fa\u6709\u6210\u4e3a\u4e16\u754c\u6700\u7545\u9500\u836f\u7269\u7684\u6f5c\u529b\uff1b\u516c\u53f8\u5176\u4ed6\u4ea7\u54c1\u8fd8\u6709\u963f\u624e\u80de\u82f7\uff08Azacitidine, Vidaza\uff09\u7f57\u7c73\u5730\u8f9b\uff08Istodax, Romidepsin\uff09\u6c99\u5229\u5ea6\u80fa\uff08Thalidomide, Thalomid\uff09\u3001\u5730\u585e\u7c73\u677e\uff08Dexamethasone, Lenadex\uff09\u4ee5\u53ca2017\u5e748\u6708\u83b7\u6279\u7684\u7a81\u7834\u6027\u767d\u8840\u75c5\u65b0\u836fIdhifa\uff08Enasidenib\uff09\u3002\u8fd1\u4e94\u5e74\u6765\u516c\u53f8\u4ea7\u54c1\u7684\u9500\u552e\u989d\u5747\u4ee5\u4e24\u4f4d\u767e\u5206\u6570\u5feb\u901f\u589e\u957f\uff1b2017\u5e74\u5168\u7403\u4ea7\u54c1\u9500\u552e\u989d\u8fbe\u5230129.73\u4ebf\u7f8e\u5143\uff08\u56fe1\uff09\uff0c\u5176\u4e2d\u5f53\u5bb6\u54c1\u79cd\u6765\u90a3\u5ea6\u80fa\u7684\u9500\u552e\u989d\u4e3a81.87\u4ebf\u7f8e\u5143\uff0c\u5bf9\u603b\u9500\u552e\u989d\u7684\u8d21\u732e\u8d85\u8fc760%\uff1b\u8be5\u836f\u662f\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u7684\u4e00\u7ebf\u7528\u836f\uff0c\u6b64\u524d\u65b0\u57fa\u4e0eNatcoPharma\u8fbe\u6210\u4e86\u4e00\u9879\u534f\u8bae\uff0c\u5c06\u5141\u8bb8\u6765\u90a3\u5ea6\u80fa\u7684\u4eff\u5236\u836f\u54c1\u57282022\u5e74\u4e8e\u6709\u9650\u7684\u8303\u56f4\u5185\u8fdb\u5165\u7f8e\u56fd\u5e02\u573a\u3002\u6b64\u5916\uff0c\u65b0\u57fa\u5934\u53f7\u94f6\u5c51\u75c5\u6cbb\u7597\u836f\u7269\u963f\u666e\u65af\u7279\u53bb\u5e74\u589e\u901f\u9887\u4e3a\u4eae\u773c\uff0c\u9500\u552e\u989d\u4e3a12.79\u4ebf\u7f8e\u5143\uff0c\u589e\u5e45\u9ad8\u8fbe26%\uff0c\u6b64\u524d\u963f\u666e\u65af\u7279\u9500\u552e\u4f4e\u4e8e\u9884\u671f\uff0c\u65b0\u57fa\u8fd8\u56e0\u6b64\u4e0b\u8c03\u4e86\u8be5\u836f2020\u5e74\u6574\u4f53\u9500\u552e\u9884\u671f\u3002<\/span><\/p>\n

\"\u4e0d\u8d70\u5bfb\u5e38\u8def\u7684\u751f\u7269\u79d1\u6280\u5de8\u5934\uff1a\u65b0\u57fa\u516c\u53f8\u63ed\u79d8\"<\/p>\n

\u56fe1\uff1a\u8fd1\u4e94\u5e74\u65b0\u57fa\u516c\u53f8\u4ea7\u54c1\u9500\u552e\u60c5\u51b5\uff08\u767e\u4e07\u7f8e\u5143\uff09<\/span><\/p>\n

\u6839\u636e\u65b0\u57fa\u53d1\u5e03\u76842018Q3\u62a5\u544a\uff08\u88681\uff09\uff0c\u6765\u90a3\u5ea6\u80fa\u548c\u65b0\u578b\u94f6\u5c51\u75c5\u836f\u7269\u963f\u666e\u65af\u7279\u9500\u552e\u548c\u76c8\u5229\u5747\u8d85\u8fc7\u9884\u671f\uff0c\u7b2c\u4e09\u5b63\u5ea6\u4ea7\u54c1\u603b\u9500\u552e\u989d\u4e3a38.9\u4ebf\u7f8e\u5143\uff0c\u5176\u4e2d\u6765\u90a3\u5ea6\u80fa\u5360\u5230\u4e8624.5\u4ebf\u7f8e\u5143\uff0c\u6765\u90a3\u5ea6\u80fa\u5728\u4eca\u5e74\u7684\u5168\u7403\u9500\u552e\u989d\u5c31\u9884\u8ba1\u5c06\u8fbe\u523097\u4ebf\u7f8e\u5143\u3002\u6839\u636e\u516c\u53f8Q3\u8d22\u62a5\u663e\u793a\uff0c\u6765\u90a3\u5ea6\u80fa\u6bd4\u53bb\u5e74\u540c\u671f\u589e\u957f18%\uff0c\u53e6\u4e00\u6b3e\u8840\u6db2\u764c\u75c7\u836f\u7269\u6cca\u9a6c\u5ea6\u80fa\u589e\u957f23%\u81f35.13\u4ebf\u7f8e\u5143\uff0c\u963f\u666e\u65af\u7279\u589e\u957f40%\u81f34.32\u4ebf\u7f8e\u5143\u3001Abraxane\u589e\u957f15%\u81f32.88\u4ebf\u7f8e\u5143\u3002\u963f\u666e\u65af\u7279\u9884\u8ba1\u57282018\u5e74\u5168\u5e74\u9500\u552e\u5c06\u8fbe\u523016\u4ebf\u7f8e\u5143\u3002<\/span><\/p>\n

\u88681\uff1a\u65b0\u57fa\u516c\u53f82018\u5e74Q3\u4ea7\u54c1\u9500\u552e\u60c5\u51b5\uff08\u767e\u4e07\u7f8e\u5143\uff09<\/span><\/span><\/p>\n

\"\u4e0d\u8d70\u5bfb\u5e38\u8def\u7684\u751f\u7269\u79d1\u6280\u5de8\u5934\uff1a\u65b0\u57fa\u516c\u53f8\u63ed\u79d8\"<\/p>\n


<\/p>\n

\u5907\u6ce8\uff1a\u6570\u636e\u6765\u81ea\u65b0\u57fa\u516c\u53f82018\u5e74Q3\u5b63\u62a5\uff0c\u62ec\u53f7\u5185\u4e3a\u7f8e\u56fd\u5e02\u573a\u6570\u636e<\/span><\/p>\n

Idhifa\uff08Enasidenib\uff09\u7531\u65b0\u57fa\u4e0eAgios Pharmaceuticals\u516c\u53f8\u5408\u4f5c\u5f00\u53d1\u7684\u9996\u4e2a\u9488\u5bf9\u80bf\u7624\u4ee3\u8c22\u7684\u6297\u764c\u836f\uff0cIdhifa\u4e8e2017\u5e748\u6708\u88abFDA\u6279\u51c6\u4e0a\u5e02\uff0c\u7528\u4e8e\u6cbb\u7597\u643a\u5e26IDH2\u57fa\u56e0\u7a81\u53d8\u7684\u590d\u53d1\/\u96be\u6cbb\u6027\u6025\u6027\u9aa8\u9ad3\u6027\u767d\u8840\u75c5\uff08AML\uff09\u60a3\u8005\u3002\u5728AML\u60a3\u8005\u4e2d\uff0c\u5927\u7ea6\u67098%-19%\u7684\u60a3\u8005\u5e26\u6709IDH2\u7a81\u53d8\u3002\u8fd9\u79cd\u7a81\u53d8\u4f1a\u6291\u5236\u6b63\u5e38\u7684\u8840\u7ec6\u80de\u53d1\u80b2\uff0c\u5bfc\u81f4\u8fc7\u591a\u4e0d\u6210\u719f\u7684\u8840\u7ec6\u80de\u4ea7\u751f\u3002Idhifa\u662f\u9996\u6b3e\u9488\u5bf9IDH2\u7a81\u53d8\u7684\u53e3\u670d\u6291\u5236\u5242\uff0c\u5b83\u53ef\u4ee5\u901a\u8fc7\u6291\u5236\u7a81\u53d8\u7684IDH2\u86cb\u767d\u6765\u63a7\u5236\u75be\u75c5\u53d1\u5c55\u3002\u4f5c\u4e3a\u65b0\u57fa\u516c\u53f8\u4e0a\u5e02\u4ea7\u54c1\u7684\u65b0\u6210\u5458\uff0c\u4eca\u5e74\u524d\u4e09\u5b63\u5ea6\u7684\u5168\u7403\u9500\u552e\u989d\u8fbe\u5230\u4e865000\u4e07\u7f8e\u5143\uff0c\u8868\u73b0\u4eae\u773c\u3002Idhifa \u83b7\u5f97\u7d20\u6709\u201c\u533b\u836f\u754c\u7684\u8bfa\u8d1d\u5c14\u5956\u201d\u7f8e\u8a89\u76842018\u5e74\u7f8e\u56fd\u76d6\u4f26\u5956\uff08Prix Galien Award\uff09\u6700\u4f73\u836f\u54c1\u5956\uff08Best Pharmaceutical Product\uff09\u7684\u6b8a\u8363\u3002<\/span><\/p>\n

\u7814\u53d1\u7ba1\u7ebf<\/span><\/p>\n

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\"\u4e0d\u8d70\u5bfb\u5e38\u8def\u7684\u751f\u7269\u79d1\u6280\u5de8\u5934\uff1a\u65b0\u57fa\u516c\u53f8\u63ed\u79d8\"<\/p>\n

\u56fe2\uff1a2012-2016\u5e74\u65b0\u57fa\u516c\u53f8\u7814\u53d1\u6295\u5165\u60c5\u51b5<\/span><\/p>\n

\u636eInforma\u6570\u636e\u5e93\u68c0\u7d22\u7ed3\u679c\uff08\u68c0\u7d22\u65e5\u671f\uff1a2018\u5e7411\u670828\u65e5\uff09\uff0c\u65b0\u57fa\u516c\u53f8\u5171\u6709\u5904\u4e8e\u5404\u4e2a\u9636\u6bb5\u7684\u836f\u7269\u8d85\u8fc7200\u4e2a\uff08\u56fe3\uff09\uff0c\u4e3b\u8981\u96c6\u4e2d\u5728\u80bf\u7624\u548c\u708e\u75c7\u4e0e\u514d\u75ab\u75be\u75c5\u9886\u57df\uff0c\u5e76\u5f00\u59cb\u6d89\u8db3\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u9886\u57df\u3002<\/span><\/p>\n

\"\u4e0d\u8d70\u5bfb\u5e38\u8def\u7684\u751f\u7269\u79d1\u6280\u5de8\u5934\uff1a\u65b0\u57fa\u516c\u53f8\u63ed\u79d8\"<\/p>\n

\u56fe3\uff1a\u6309\u7ec6\u5206\u6cbb\u7597\u9886\u57df\u65b0\u57fa\u516c\u53f8\u5404\u9636\u6bb5\u836f\u7269\u7684\u5206\u5e03\u60c5\u51b5<\/span><\/p>\n


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\u3010\u53c2\u8003\u8d44\u6599\u3011<\/span><\/p>\n

1. \u65b0\u57fa\u516c\u53f8\u5b98\u7f51. <\/span>https:\/\/www.celgene.com\/<\/span><\/p>\n

2. \u65b0\u57fa\u516c\u53f82017\u5e74\u5e74\u5ea6\u62a5\u544a.<\/span><\/p>\n

3. \u65b0\u57fa\u516c\u53f8\u7814\u53d1\u7ba1\u7ebf\uff1ahttps:\/\/www.celgene.com\/research-development\/pipeline-pdf\/.<\/span><\/p>\n

4. Informa\u6570\u636e\u5e93, \u68c0\u7d22\u65e5\u671f: 2018\u5e7411\u670828\u65e5.<\/span><\/p>\n


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\u7248\u6743\u58f0\u660e<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

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