{"id":82197,"date":"2019-03-06T00:00:50","date_gmt":"2019-04-11T06:58:27","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/82197\/"},"modified":"2019-04-11T14:58:29","modified_gmt":"2019-04-11T06:58:29","slug":"ad7e3d134b","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/82197\/","title":{"rendered":"\u72ec\u5bb6\uff01\u6052\u7ffc\u751f\u7269\u5f15\u8fdb\u53f0\u6e7e\u666f\u51ef\u751f\u6280\u4e24\u6b3eNASH\u65b0\u836f\uff01"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<section  style=\"max-width: 100%;box-sizing: border-box;font-size: 16px;font-variant-numeric: normal;font-variant-east-asian: normal;letter-spacing: 0.544px;line-height: 25.6px;white-space: normal;widows: 1;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<p style=\"white-space: normal;text-align: center;\">\n<p style=\"white-space: normal;text-align: center;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI4OTIzMzcwMw==&amp;mid=2659317518&amp;idx=1&amp;sn=e9cd47974c4f8720c1ef0dc541da1a92&amp;chksm=f7471946c030905064bbd7afa42ee857086c9951df2b569b90175f1987dcb14ed151e9e90258&amp;scene=21#wechat_redirect\" target=\"_blank\"  >\u3010\u516c\u76ca\u8bba\u575b\u30114+7\u53ea\u77e5\u5371\u673a\u5c06\u81f3\uff0c\u5374\u4e0d\u77e5\u672a\u6765\u5df2\u6765 | \u7acb\u5373\u6ce8\u518c\u201c\u8000\u8363\u534e\u5a01\u201d\u533b\u836f\u9ad8\u5cf0\u8bba\u575b<\/a><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><strong>\u53f0\u6e7e\u4e0a\u5e02\u516c\u53f8\u666f\u51ef\u751f\u6280\u8fd1\u65e5\u5ba3\u5e03\uff0c\u65d7\u4e0b\u6cbb\u7597\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u708e(NASH)\u65b0\u836fJKB-122\u3001JKB-133\uff0c\u72ec\u5bb6\u6388\u6743\u6052\u7ffc\u533b\u836f(\u4e0a\u6d77)\u516c\u53f8\u5f00\u53d1\u4e9a\u6d32\u5e02\u573a\uff0c\u7b7e\u7ea6\u91d1200\u4e07\u7f8e\u91d1\u548c\u672a\u6765\u6700\u9ad8\u53ef\u8fbe2400\u4e07\u7f8e\u91d1\u7684\u91cc\u7a0b\u7891\u91d1\u4ee5\u53ca\u4e0a\u5e02\u540e\u7684\u9500\u552e\u5206\u6da6\u3002<\/strong><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;font-size: 16px;font-variant-numeric: normal;font-variant-east-asian: normal;letter-spacing: 0.544px;line-height: 25.6px;white-space: normal;widows: 1;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"\"       style=\"box-sizing: border-box !important;overflow-wrap: break-word !important;width: 677px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/4-1554965907.jpg\" alt=\"\u72ec\u5bb6\uff01\u6052\u7ffc\u751f\u7269\u5f15\u8fdb\u53f0\u6e7e\u666f\u51ef\u751f\u6280\u4e24\u6b3eNASH\u65b0\u836f\uff01\" title=\"\u72ec\u5bb6\uff01\u6052\u7ffc\u751f\u7269\u5f15\u8fdb\u53f0\u6e7e\u666f\u51ef\u751f\u6280\u4e24\u6b3eNASH\u65b0\u836f\uff01\"  \/><\/p>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;font-size: 16px;font-variant-numeric: normal;font-variant-east-asian: normal;letter-spacing: 0.544px;line-height: 25.6px;white-space: normal;widows: 1;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u4f9d\u534f\u8bae\uff0c\u666f\u51ef\u5c06\u534f\u52a9\u7edf\u7b79\u6309\u7167\u56fd\u9645\u591a\u4e2d\u5fc3\u65b9\u5f0f\u5f00\u5c55JKB-122\u3001JKB-133\u7b2cII\u671f\u548c\u7b2cIII\u671f\u7684\u4e34\u5e8a\u7814\u7a76\uff0c\u6052\u7ffc\u5219\u8d1f\u8d23\u5b9e\u65bd\u548c\u7ba1\u7406\u4e9a\u6d32\u533a\u7684\u4e34\u5e8a\u7814\u7a76\u5de5\u4f5c\uff0c\u8d1f\u62c5\u8be52\u4e2a\u9879\u76ee\u5728\u4e9a\u6d32\u533a\u7684\u4e34\u5e8a\u7814\u7a76\u8d39\u7528\u4e0e\u836f\u54c1\u6ce8\u518c\u76f8\u5173\u8d39\u7528\uff0c\u5e76\u4e8e\u83b7\u5f97\u6279\u51c6\u4e0a\u5e02\u540e\uff0c\u8d1f\u8d23\u8be5\u9879\u76ee\u5728\u4e9a\u6d32\u533a\u7684\u5546\u4e1a\u5316\u63a8\u5e7f\u3002<\/p>\n<p style=\"text-align: center;\"><img class=\"\"      style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/10-1554965908.jpg\" alt=\"\u72ec\u5bb6\uff01\u6052\u7ffc\u751f\u7269\u5f15\u8fdb\u53f0\u6e7e\u666f\u51ef\u751f\u6280\u4e24\u6b3eNASH\u65b0\u836f\uff01\" title=\"\u72ec\u5bb6\uff01\u6052\u7ffc\u751f\u7269\u5f15\u8fdb\u53f0\u6e7e\u666f\u51ef\u751f\u6280\u4e24\u6b3eNASH\u65b0\u836f\uff01\"><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u666f\u51ef\u751f\u6280\u8868\u793a\uff0c\u4e0e\u6052\u7ffc\u7684\u5408\u4f5c\u6848\uff0c\u4e3b\u8981\u662f\u534f\u52a9\u8be5\u516c\u53f8\u5f00\u53d1\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u708e(NASH)\u533b\u7597\u5e02\u573a\u53ca\u5176\u4ed6\u9002\u5e94\u75c7\u6cd5\u89c4\u6838\u51c6\u53ca\u5546\u54c1\u5316\u6d3b\u52a8\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;font-size: 16px;font-variant-numeric: normal;font-variant-east-asian: normal;letter-spacing: 0.544px;line-height: 25.6px;white-space: normal;widows: 1;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;vertical-align: middle;display: inline-block;line-height: 0;overflow-wrap: break-word !important;\"><img class=\"\"     style=\"box-sizing: border-box;vertical-align: middle;overflow-wrap: break-word !important;width: 474px !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/2-1554965908.jpeg\" alt=\"\u72ec\u5bb6\uff01\u6052\u7ffc\u751f\u7269\u5f15\u8fdb\u53f0\u6e7e\u666f\u51ef\u751f\u6280\u4e24\u6b3eNASH\u65b0\u836f\uff01\" title=\"\u72ec\u5bb6\uff01\u6052\u7ffc\u751f\u7269\u5f15\u8fdb\u53f0\u6e7e\u666f\u51ef\u751f\u6280\u4e24\u6b3eNASH\u65b0\u836f\uff01\"  \/><\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;font-size: 16px;font-variant-numeric: normal;font-variant-east-asian: normal;letter-spacing: 0.544px;line-height: 25.6px;white-space: normal;widows: 1;background-color: rgb(255, 255, 255);overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u975e\u9152\u7cbe\u6027\u8102\u80aa\u6027\u809d\u708e(NASH\uff0cnonalcoholic steatohepatitis)\u662f\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u7684\u4e00\u79cd\u6781\u7aef\u53d1\u5c55\u5f62\u5f0f\uff0c\u5b9a\u4e49\u4e3a\u4f34\u968f\u6709\u708e\u75c7\u53ca\u809d\u7ec6\u80de\u635f\u4f24\u7684\u8102\u80aa\u53d8\u6027\u73b0\u8c61\u7684\u51fa\u73b0\u3002NASH\u53ef\u5bfc\u81f4\u665a\u671f\u809d\u810f\u7ea4\u7ef4\u5316\u3001\u809d\u786c\u5316\u3001\u809d\u8870\u7aed\u53ca\u809d\u810f\u80bf\u7624\u7684\u4ea7\u751f\u3002\u5728\u8fc7\u53bb\u768420\u5e74\u91cc\uff0cNAFLD\u53d1\u75c5\u6570\u5df2\u7ffb\u500d\uff0c\u73b0\u5df2\u6210\u4e3a\u897f\u65b9\u56fd\u5bb6\u4e2d\u6700\u4e3a\u5e38\u89c1\u7684\u809d\u810f\u75be\u75c5\u3002\u5bfc\u81f4NASH\u7684\u4e3b\u8981\u5371\u9669\u56e0\u7d20\u5305\u62ec\u80a5\u80d6\u30012\u578b\u7cd6\u5c3f\u75c5(T2DM)\u53ca\u8840\u8102\u5f02\u5e38\u4e0e\u4ee3\u8c22\u7efc\u5408\u5f81\u3002<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><strong>&nbsp;<\/strong><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><strong><span style=\"color: rgb(0, 82, 255);\">\u666f\u51ef\u751f\u7269\u79d1\u6280\u80a1\u4efd\u6709\u9650\u516c\u53f8\u6210\u7acb\u4e8e2011\u5e74\uff0c\u7531\u5177\u836f\u7269\u5f00\u53d1\u591a\u5e74\u7ecf\u9a8c\u7684\u65c5\u7f8e\u535a\u58eb\u5434\u68ee\u6d32\u521b\u7acb\uff0c2013\u5e74\u5e95\u5ef6\u63fd\u77f3\u82f1\u73e0\u535a\u58eb\u4e3a\u9996\u7684\u5de5\u7814\u9662\u56e2\u961f\u52a0\u5165\u3002\u805a\u7126\u4e8e\u5c0f\u5206\u5b50\u65b0\u836f\u5f00\u53d1\uff0c\u5728\u7814\u65b0\u836f\u7684\u9002\u5e94\u75c7\u5305\u62ec\u81ea\u4f53\u514d\u75ab\u75be\u75c5\u3001\u4ee3\u8c22\u4ee5\u53ca\u611f\u67d3\u9020\u6210\u7684\u6162\u6027\u809d\u708e\u4ee5\u53ca\u4e0d\u542b\u7c7b\u56fa\u9187\u7684\u8fc7\u654f\/\u6c14\u5598\u65b0\u836f\u3002<\/span><\/strong><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\"><span style=\"color: rgb(0, 82, 255);\"><strong>\u6052\u7ffc\u751f\u7269\u533b\u836f\u4e13\u6ce8\u4e8e\u5f00\u53d1\u521b\u65b0\u81ea\u4e3b\u514d\u75ab\u3001\u6d88\u5316\u9053\u548c\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u6cbb\u7597\u7684\u836f\u7269\uff0c\u8be5\u516c\u53f8\u662f\u676d\u5dde\u6cf0\u683c\u533b\u836f\u53c2\u80a1\u516c\u53f8\u3002<\/strong><\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"\"      style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/1-1554965908.png\" alt=\"\u72ec\u5bb6\uff01\u6052\u7ffc\u751f\u7269\u5f15\u8fdb\u53f0\u6e7e\u666f\u51ef\u751f\u6280\u4e24\u6b3eNASH\u65b0\u836f\uff01\" title=\"\u72ec\u5bb6\uff01\u6052\u7ffc\u751f\u7269\u5f15\u8fdb\u53f0\u6e7e\u666f\u51ef\u751f\u6280\u4e24\u6b3eNASH\u65b0\u836f\uff01\"><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;\">\u6b64\u524d\u6709\u5206\u6790\u5e08\u9884\u6d4b\uff0c\u968f\u7740\u8102\u80aa\u809d\u4eba\u7fa4\u65e5\u76ca\u6269\u5927\uff0cNASH \u6cbb\u7597\u5e02\u573a\u5c06\u8fbe\u5230 200 \u4ebf\u81f3 350 \u4ebf\u7f8e\u5143\uff0c\u56e0\u6b64\u6210\u4e3a\u4f17\u591a\u836f\u4f01\u96c6\u4e2d\u5f00\u53d1\u7684\u9886\u57df\u3002\u809d\u810f\u836f\u5de8\u5934\u5409\u5217\u5fb7\uff08Gilead Sciences\uff09&nbsp;<span style=\"max-width: 100%;box-sizing: border-box;letter-spacing: 0px;overflow-wrap: break-word !important;\">2 \u6708 11 \u65e5\u5bf9\u5916\u5ba3\u5e03\uff0c\u516c\u53f8\u65d7\u4e0bNASH\u836f\u7269 selonsertib \u7684\u4e00\u9879\u5173\u952e 3 \u671f\u8bd5\u9a8c STELLAR-4 \u672a\u80fd\u8fbe\u5230\u5176\u4e3b\u8981\u76ee\u6807\u3002\u8be5\u6d88\u606f\u5bfc\u81f4\u5409\u5229\u5fb7\u5f53\u65e5\u80a1\u4ef7\u80a1\u4ef7\u4e0b\u8dcc 4.6%\u3002<\/span>\u7f8e\u56fd\u751f\u7269\u5236\u836f\u516c\u53f8Intercept\u5ba3\u5e03\uff0c\u5176\u5f00\u53d1\u7684<span style=\"max-width: 100%;box-sizing: border-box;letter-spacing: 0px;overflow-wrap: break-word !important;\">NASH\u5728\u7814\u65b0\u836f\u5965\u8d1d\u80c6\u9178\uff08Ocaliva\uff09\u5728\u4e00\u98793\u671f\u8bd5\u9a8c\u4e2d\u8fbe\u5230\u4e3b\u8981\u7ec8\u70b9\uff0c\u663e\u8457\u6539\u5584\u809d\u810f\u7ea4\u7ef4\u5316\uff0c\u6709\u671b\u6210\u4e3a\u5168\u7403\u7b2c\u4e00\u6b3e\u6cbb\u7597NASH\u7684\u65b0\u836f\u3002<\/span><span style=\"max-width: 100%;box-sizing: border-box;letter-spacing: 0px;overflow-wrap: break-word !important;\">2018\u5e741\u670812\u65e5\uff0c\u56fd\u5185\u9996\u4e2a NASH \u65b0\u836f\u2014\u2014<\/span><span style=\"max-width: 100%;box-sizing: border-box;letter-spacing: 0px;overflow-wrap: break-word !important;\">\u4f17\u751f\u836f\u4e1a\u4e0e\u8054\u5408\u5f00\u53d1\u7684<\/span><span style=\"max-width: 100%;box-sizing: border-box;letter-spacing: 0px;overflow-wrap: break-word !important;\"><span class=\"Apple-converted-space\">&nbsp;<\/span>ZSP1601\u83b7\u6279\u4e34\u5e8a\uff0c\u82e5\u666f\u51ef\u4e0e\u6052\u7ffc\u7684\u4e34\u5e8a\u8bd5\u9a8c\u8fdb\u5c55\u987a\u5229\uff0cJKB-122\u5c06\u6210\u4e3a\u56fd\u5185\u9996\u5bb6\u4e0a\u5e02\u7684NASH\u65b0\u836f\u3002<\/span><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;overflow-wrap: break-word !important;text-align: center;\"><span style=\"max-width: 100%;box-sizing: border-box;letter-spacing: 0px;overflow-wrap: break-word !important;\"><img   class=\"\"   src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/7-1554965908.jpg\" alt=\"\u72ec\u5bb6\uff01\u6052\u7ffc\u751f\u7269\u5f15\u8fdb\u53f0\u6e7e\u666f\u51ef\u751f\u6280\u4e24\u6b3eNASH\u65b0\u836f\uff01\" title=\"\u72ec\u5bb6\uff01\u6052\u7ffc\u751f\u7269\u5f15\u8fdb\u53f0\u6e7e\u666f\u51ef\u751f\u6280\u4e24\u6b3eNASH\u65b0\u836f\uff01\"  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[&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":82198,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/82197"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=82197"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/82197\/revisions"}],"predecessor-version":[{"id":82205,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/82197\/revisions\/82205"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/82198"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=82197"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=82197"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=82197"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}