{"id":82301,"date":"2019-03-28T00:00:50","date_gmt":"2019-04-11T06:59:40","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/82301\/"},"modified":"2019-04-11T14:59:43","modified_gmt":"2019-04-11T06:59:43","slug":"f8c0bb1a7d","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/82301\/","title":{"rendered":"\u8fd1\u4e00\u5e74\u7cd6\u5c3f\u75c5\u9886\u57df\u57fa\u7840\u4e13\u5229\u6982\u51b5"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"text-indent: 2em;\"><span style=\"font-size: 15px;\">\u636eClarivate Analytics Integrity\u6570\u636e\u5e93\uff08\u68c0\u7d22\u65f6\u95f42019\u5e743\u670815\u65e5\uff09\uff0c\u8fd1\u4e00\u5e74\u5168\u7403\u9996\u6b21\u516c\u5f00\u7684\u57fa\u7840\u4e13\u5229\u5171\u8ba127155\u4ef6\uff0c\u672c\u9636\u6bb5\u4e13\u5229\u6d89\u53ca\u7684\u6cbb\u7597\u9886\u57df\u6709\u80bf\u7624\u3001\u708e\u75c7\u53ca\u611f\u67d3\u6027\u75be\u75c5\u3001\u795e\u7ecf\u7cbe\u795e\u75be\u75c5\u3001\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3001\u5fc3\u8840\u7ba1\u75be\u75c5\u3001\u4ee3\u8c22\u6027\u75be\u75c5\u7b49\u3002\u6309\u5177\u4f53\u75be\u75c5\u6765\u5206\uff0c\u708e\u75c7\u3001\u7ec6\u83cc\u6027\u75be\u75c5\u3001\u963f\u5c14\u5179\u6d77\u9ed8\u75c7\u3001\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3001\u7cd6\u5c3f\u75c5\u4f4d\u5217\u524d\u4e94\uff0c\u4e13\u5229\u4ef6\u6570\u8d85\u8fc7400\u4ef6\u7684\u9002\u5e94\u75c7\u5982\u56fe1\u6240\u793a\uff08\u6709\u4e9b\u4e13\u5229\u6d89\u53ca\u4e0d\u6b62\u4e00\u79cd\u9002\u5e94\u75c7\uff1b\u53e6\uff0c\u80bf\u7624\u9886\u57df\u7684\u4e13\u5229\u7533\u8bf7\u591a\u672a\u8a00\u660e\u7528\u4e8e\u4f55\u79cd\u80bf\u7624\uff0c\u5f52\u7eb3\u65f6\u672a\u5217\u5165\u5177\u4f53\u75be\u75c5\u4e2d\uff09\u3002<\/span><\/p>\n<\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 14px;\">\u56fe1\uff1a\u8fd1\u4e00\u5e74\u5168\u7403\u9996\u6b21\u516c\u5f00\u7684\u57fa\u7840\u4e13\u5229\u6d89\u53ca\u7684\u5177\u4f53\u75be\u75c5\u5206\u5e03\u60c5\u51b5\uff08\u4ec5\u5c55\u793a\u2265400\u4ef6\u7684\u75be\u75c5\uff09<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 14px;\"><br  \/><\/span><\/p>\n<p style=\"text-indent: 2em;\"><span style=\"font-size: 15px;\">\u672c\u9636\u6bb5\u4e13\u5229\u4e2d\uff0c\u4ee5\u7cd6\u5c3f\u75c5\u4e13\u5229\u4e3a\u4f8b\uff0c\u6d89\u53ca\u8be5\u75be\u75c5\u9886\u57df\u7684\u4e13\u5229\u5171\u8ba1826\u4ef6\uff0c\u4ece\u4e13\u5229\u7c7b\u578b\u4e0a\u770b\uff0c\u836f\u7269\u7269\u8d28\uff08Drug Substances\uff09\u6570\u91cf\u6700\u591a\uff0c\u6709338\u4ef6\uff0c\u53e6\u6709\u7528\u9014\u3001\u5929\u7136\u4ea7\u7269\u3001\u6cbb\u7597\u86cb\u767d\u3001\u5242\u578b\u53ca\u7ec4\u6210\u7b49\u591a\u4e2a\u4e13\u5229\u7c7b\u578b\uff08\u56fe2\uff09\u3002<\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"rich_pages\"          style=\"width: 100%;height: auto;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/7-1554965980.jpg\" alt=\"\u8fd1\u4e00\u5e74\u7cd6\u5c3f\u75c5\u9886\u57df\u57fa\u7840\u4e13\u5229\u6982\u51b5\" title=\"\u8fd1\u4e00\u5e74\u7cd6\u5c3f\u75c5\u9886\u57df\u57fa\u7840\u4e13\u5229\u6982\u51b5\"  \/><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 14px;\">\u56fe2\uff1a\u8fd1\u4e00\u5e74\u5168\u7403\u9996\u6b21\u516c\u5f00\u7684\u7cd6\u5c3f\u75c5\u57fa\u7840\u4e13\u5229\u7c7b\u578b\u5206\u5e03\u60c5\u51b5\uff08\u4e13\u5229\u6570\u226530\uff09<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 14px;\"><br  \/><\/span><\/p>\n<p style=\"text-indent: 2em;\"><span style=\"font-size: 15px;\">\u4ece\u4e13\u5229\u6d89\u53ca\u836f\u7269\u4f5c\u7528\u673a\u5236\u770b\uff0c\u7cd6\u5c3f\u75c5\u76f8\u5173\u836f\u7269\u7269\u8d28\u4e13\u5229\u591a\u6d89\u53ca\u4fe1\u53f7\u901a\u8def\u7684\u8c03\u8282\uff0c\u6d89\u53ca\u4e13\u5229\u6570\u91cf\u6700\u591a\u7684\u4f5c\u7528\u673a\u5236\u4e3aGLP-1\u53d7\u4f53\u6fc0\u52a8\u5242\uff0819\u4ef6\uff09\u3001\u03b1-\u8461\u8404\u7cd6\u82f7\u9176\u6291\u5236\u5242\uff0817\u4ef6\uff09\u548c\u8868\u89c2\u9057\u4f20\u4fee\u9970\u8c03\u8282\u5242\uff0813\u4ef6\uff09\u3002\u5e38\u7528\u80bf\u7624\u6cbb\u7597\u836f\u7269\u5982EGFR\u6291\u5236\u5242\u5305\u62ecEGFR\uff08Leu858Arg\/Thr790Met\u53cc\u7a81\u53d8\uff09\u6291\u5236\u5242\uff085\u4ef6\uff09\u548cEGFR\uff08HER1\uff1berbB1\uff09\u6291\u5236\u5242\uff085\u4ef6\uff09\u6216\u53ef\u7528\u4e8e\u7cd6\u5c3f\u75c5\u7684\u6cbb\u7597\uff08\u56fe3\uff09\u3002<\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"rich_pages\"          style=\"width: 100%;height: auto;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/4-1554965981.jpg\" alt=\"\u8fd1\u4e00\u5e74\u7cd6\u5c3f\u75c5\u9886\u57df\u57fa\u7840\u4e13\u5229\u6982\u51b5\" title=\"\u8fd1\u4e00\u5e74\u7cd6\u5c3f\u75c5\u9886\u57df\u57fa\u7840\u4e13\u5229\u6982\u51b5\"  \/><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 14px;\">\u56fe3\uff1a\u8fd1\u4e00\u5e74\u516c\u5f00\u7684\u6d89\u53ca\u7cd6\u5c3f\u75c5\u9886\u57df\u7684\u57fa\u7840\u4e13\u5229\uff08\u836f\u7269\u7269\u8d28\u4e13\u5229\uff09\u4f5c\u7528\u673a\u5236\u5206\u5e03<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 14px;\"><br  \/><\/span><\/p>\n<p style=\"text-indent: 2em;\"><span style=\"font-size: 15px;\">\u4ece\u4e13\u5229\u6743\u4eba\u6765\u770b\uff0c\u8fd1\u4e00\u5e74\u6d89\u53ca\u7cd6\u5c3f\u75c5\u9886\u57df\u7684\u836f\u7269\u7269\u8d28\u4e13\u5229\u6570\u91cf\u6700\u591a\u7684\u673a\u6784\u662f\u4e2d\u56fd\u836f\u79d1\u5927\u5b66\uff0811\u4ef6\uff09\uff0cZealand\u5236\u836f\u516c\u53f8\u3001\u6768\u68ee\u3001\u5b89\u8fdb\u7684\u4e13\u5229\u6570\u91cf\u7d27\u968f\u5176\u540e\uff0c\u5747\u67096\u4ef6\u57fa\u7840\u4e13\u5229\u516c\u5e03\uff0c\u5176\u5b83\u5236\u836f\u673a\u6784\u5982Sunshine Lake Pharma\uff085\u4ef6\uff09\u3001Zhengzhou Tetranov Biopharm\uff085\u4ef6\uff09\u3001\u8d35\u5dde\u533b\u79d1\u5927\u5b66\uff085\u4ef6\uff09\u548cHanmi\uff085\u4ef6\uff09\u4e5f\u6709\u4e13\u5229\u88ab\u516c\u5e03\uff08\u56fe4\uff09\u3002\u4e0b\u9762\u6211\u4eec\u5bf9\u4e2d\u56fd\u836f\u79d1\u5927\u5b66\u3001Zealand\u5236\u836f\u516c\u53f8\u3001\u6768\u68ee\u548c\u5b89\u8fdb\u516c\u5e03\u7684\u4e13\u5229\u8fdb\u884c\u7b80\u8ff0\u3002<\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"rich_pages\"          style=\"width: 100%;height: auto;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/8-1554965981.jpg\" alt=\"\u8fd1\u4e00\u5e74\u7cd6\u5c3f\u75c5\u9886\u57df\u57fa\u7840\u4e13\u5229\u6982\u51b5\" title=\"\u8fd1\u4e00\u5e74\u7cd6\u5c3f\u75c5\u9886\u57df\u57fa\u7840\u4e13\u5229\u6982\u51b5\"  \/><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 14px;\">\u56fe4\uff1a\u8fd1\u4e00\u5e74\u516c\u5f00\u7684\u6d89\u53ca\u7cd6\u5c3f\u75c5\u9886\u57df\u7684\u57fa\u7840\u4e13\u5229\uff08\u836f\u7269\u7269\u8d28\u4e13\u5229\uff09\u7684\u4e13\u5229\u6743\u4eba\u5206\u5e03\uff08\u4e13\u5229\u6570\u22655\u4ef6\uff09<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 14px;\"><br  \/><\/span><\/p>\n<p style=\"text-indent: 2em;\"><span style=\"font-size: 15px;\">\u4e2d\u56fd\u836f\u79d1\u5927\u5b66\u8fd1\u4e00\u5e74\u6d89\u53ca\u7cd6\u5c3f\u75c5\u9886\u57df\u7684\u57fa\u7840\u4e13\u5229\u5171\u8ba111\u4ef6\uff0c\u5176\u4e2dCN 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title=\"\u8fd1\u4e00\u5e74\u7cd6\u5c3f\u75c5\u9886\u57df\u57fa\u7840\u4e13\u5229\u6982\u51b5\"  \/><\/p>\n<p style=\"text-indent: 2em;\"><span style=\"font-size: 15px;\"><\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"rich_pages\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/1-1554965982.jpeg\" alt=\"\u8fd1\u4e00\u5e74\u7cd6\u5c3f\u75c5\u9886\u57df\u57fa\u7840\u4e13\u5229\u6982\u51b5\" title=\"\u8fd1\u4e00\u5e74\u7cd6\u5c3f\u75c5\u9886\u57df\u57fa\u7840\u4e13\u5229\u6982\u51b5\"  \/><\/p>\n<p style=\"text-indent: 2em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"text-indent: 2em;\"><span style=\"font-size: 15px;\">Zealand\u5236\u836f\u516c\u53f8\u8fd1\u4e00\u5e74\u6d89\u53ca\u7cd6\u5c3f\u75c5\u9886\u57df\u57fa\u7840\u4e13\u5229\u5171\u67096\u4ef6\uff0c\u5176\u4e2d\uff0cWO2018104561\u3001WO 2018104558\u3001WO 2018103868\u516c\u5f00\u4e86\u4e00\u7c7b\u80bd\u7c7b\u5316\u5408\u7269\uff0c\u4f5c\u4e3a\u9170\u57fa\u5316GLP-1\/GLP-2\u53cc\u6fc0\u52a8\u5242\uff0c\u53ef\u964d\u4f4e\u8840\u7cd6\u6c34\u5e73\uff0c\u5e76\u53ef\u80fd\u7528\u4e8e\u6cbb\u7597\u4e0e\u80a0\u9053\u635f\u4f24\/\u529f\u80fd\u969c\u788d\u6216\u4ee3\u8c22\u529f\u80fd\u969c\u788d\u76f8\u5173\u7684\u75be\u75c5\uff0c\u5305\u62ec\u5438\u6536\u4e0d\u826f\u3001\u7cd6\u5c3f\u75c5\u3001\u80a5\u80d6\u3001\u574f\u6b7b\u6027\u5c0f\u80a0\u7ed3\u80a0\u708e\u3001\u9ad8\u8840\u538b\u3001\u708e\u75c7\u4ee5\u53ca\u4ee3\u8c22\u7efc\u5408\u5f81\u548c\u5316\u7597\u653e\u7597\u5f15\u8d77\u7684\u7c98\u819c\u708e\u7b49\u75be\u75c5\uff08\u88682\uff09\u3002<\/span><\/p>\n<p style=\"text-align: center;\"><img class=\"rich_pages\"          style=\"width: 100%;height: auto;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/0-1554965982.jpeg\" alt=\"\u8fd1\u4e00\u5e74\u7cd6\u5c3f\u75c5\u9886\u57df\u57fa\u7840\u4e13\u5229\u6982\u51b5\" title=\"\u8fd1\u4e00\u5e74\u7cd6\u5c3f\u75c5\u9886\u57df\u57fa\u7840\u4e13\u5229\u6982\u51b5\"  \/><\/p>\n<p style=\"text-indent: 2em;\"><span style=\"font-size: 15px;\"><\/span><\/p>\n<p style=\"text-indent: 2em;\"><span style=\"font-size: 15px;\"><br  \/><\/span><\/p>\n<p style=\"text-indent: 2em;\"><span style=\"font-size: 15px;\">\u6768\u68ee\u8fd1\u4e00\u5e74\u6d89\u53ca\u7cd6\u5c3f\u75c5\u9886\u57df\u57fa\u7840\u4e13\u5229\u5171\u8ba16\u4ef6\uff0c\u5176\u4e2d\uff0cWO 2018109088\u516c\u5f00\u4e86\u4e00\u79cd\u6c2e\u6742\u73af\u5e9a\u70f7\u5316\u5408\u7269\u3001WO 2018050684\u516c\u5f00\u4e86\u4e00\u79cd\u7194\u89e3\u53cc\u73af\u5316\u5408\u7269\u3001WO 2018050686\u516c\u5f00\u4e86\u4e00\u79cd\u87ba\u73af\u53cc\u73af\u5316\u5408\u7269\uff0c\u5747\u53ef\u4f5c\u4e3a\u591a\u53d1\u6027\u5185\u5206\u6ccc\u817a\u76241\u578b\u57fa\u56e0\u7f16\u7801\u86cb\u767d\uff08Menin\uff09\/\u6df7\u5408\u8c31\u7cfb\u767d\u8840\u75c5\u57fa\u56e01\uff08Mixed lineage leukemia gene 1\uff09\u86cb\u767d-\u86cb\u767d\u76f8\u4e92\u4f5c\u7528\u6291\u5236\u5242\uff0c\u7528\u4e8e\u764c\u75c7\uff0c\u9aa8\u9ad3\u53d1\u80b2\u4e0d\u826f\u7efc\u5408\u5f81\u4ee5\u53ca\u7cd6\u5c3f\u75c5\u7684\u6cbb\u7597\uff08\u88683\uff09\u3002<\/span><\/p>\n<p style=\"text-indent: 2em;\"><span style=\"font-size: 15px;\">Menin\u662f\u4e00\u79cd\u80bf\u7624\u6291\u5236\u86cb\u767d\uff0c\u5b83\u7531MEN1\u57fa\u56e0\uff08Multiple Endocrine Neoplasia type 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style=\"text-align: center;\"><img class=\"rich_pages\"          style=\"width: 100%;height: auto;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/7-1554965983.jpeg\" alt=\"\u8fd1\u4e00\u5e74\u7cd6\u5c3f\u75c5\u9886\u57df\u57fa\u7840\u4e13\u5229\u6982\u51b5\" title=\"\u8fd1\u4e00\u5e74\u7cd6\u5c3f\u75c5\u9886\u57df\u57fa\u7840\u4e13\u5229\u6982\u51b5\"  \/><\/p>\n<p style=\"text-indent: 2em;\"><span style=\"font-size: 15px;\"><\/span><\/p>\n<p><span style=\"font-size: 12px;color: rgb(136, 136, 136);\"><br  \/><\/span><\/p>\n<p><span style=\"font-size: 12px;color: rgb(136, 136, 136);\">\u3010\u53c2\u8003\u8d44\u6599\u3011<\/span><\/p>\n<p><span style=\"font-size: 12px;color: rgb(136, 136, 136);\">1.&nbsp;&nbsp;&nbsp;Clarivate Analytics Integrity\u6570\u636e\u5e93\uff0c\u68c0\u7d22\u65e5\uff1a2019\u5e7403\u670820\u65e5\u3002<\/span><\/p>\n<p><span style=\"font-size: 12px;color: rgb(136, 136, 136);\">2.&nbsp;&nbsp;&nbsp;\u4e07\u8c61\u4e91\u6570\u636e\u5e93\uff0c\u68c0\u7d22\u65e5\uff1a2019\u5e7403\u670820\u65e5\u3002<\/span><\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u636eClarivate Analytics Integrity\u6570\u636e\u5e93\uff08\u68c0\u7d22\u65f6\u95f42019\u5e743\u670815\u65e5\uff09\uff0c\u8fd1\u4e00\u5e74\u5168\u7403 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":82302,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/82301"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=82301"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/82301\/revisions"}],"predecessor-version":[{"id":82311,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/82301\/revisions\/82311"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/82302"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=82301"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=82301"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=82301"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}