{"id":82452,"date":"2019-04-14T00:00:50","date_gmt":"2019-04-17T02:53:35","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/82452\/"},"modified":"2019-04-17T10:53:39","modified_gmt":"2019-04-17T02:53:39","slug":"8125fb2c17","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/82452\/","title":{"rendered":"\u786c\u8d27\uff01\u6df1\u5ea6\u89e3\u8bfb\u5206\u6790\u65b9\u6cd5\u5b66\u9a8c\u8bc1\u5404\u9879\u5173\u952e\u6307\u6807\u8981\u6c42"},"content":{"rendered":"
\n

\u4e00\u3001\u65b9\u6cd5\u5b66\u9a8c\u8bc1\u7684\u76ee\u7684\u53ca\u610f\u4e49<\/span><\/strong><\/span><\/p>\n

1. \u76ee\u7684\uff1a\u5206\u6790\u65b9\u6cd5\u7684\u9a8c\u8bc1\u662f\u4e3a\u4e86\u8bc1\u660e\u8be5\u5206\u6790\u65b9\u6cd5\u4e0e\u5176\u9884\u671f\u76ee\u7684\u76f8\u9002\u5e94\u3002<\/span><\/p>\n

2. \u9700\u9a8c\u8bc1\u7684\u5206\u6790\u65b9\u6cd5\u7c7b\u578b<\/span><\/p>\n

\u2460 \u9274\u522b\u8bd5\u9a8c<\/span>
\u2461 <\/span>\u6742\u8d28\u7684\u5b9a\u91cf\u8bd5\u9a8c<\/span>
\u2462 <\/span>\u6742\u8d28\u63a7\u5236\u7684\u9650\u5ea6\u8bd5\u9a8c<\/span>
\u2463 <\/span>\u539f\u6599\u836f\u6216\u5236\u5242\u4e2d\u6d3b\u6027\u6210\u5206\u4ee5\u53ca\u5236\u5242\u4e2d\u9009\u5b9a\u7ec4\u5206\u7684\u5b9a\u91cf\u8bd5\u9a8c\u3002<\/span><\/span><\/p>\n

\n

\u8bd5\u9a8c\u7c7b\u578b\u5982\u4e0b\uff1a<\/span><\/p>\n

\u2460 \u9274\u522b\u8bd5\u9a8c\u65e8\u5728\u786e\u8bc1\u6837\u54c1\u4e2d\u7684\u4e00\u79cd\u88ab\u6d4b\u7269\u7684\u7279\u6027\u3002\u901a\u5e38\u5c06\u6837\u54c1\u7684\u6027\u8d28\uff08\u5982\u5149\u8c31\u3001\u8272\u8c31\u884c\u4e3a\u3001\u5316\u5b66\u53cd\u5e94\u6027\u7b49\uff09 \u4e0e\u53c2\u6bd4\u5bf9\u7167\u54c1\u7684\u6027\u8d28\u8fdb\u884c\u6bd4\u5bf9\u3002<\/span>
\u2461 <\/span>\u6742\u8d28\u68c0\u67e5\u662f\u6307\u6837\u54c1\u4e2d\u6742\u8d28\u7684\u5b9a\u91cf\u68c0\u6d4b\u6216\u9650\u5ea6\u68c0\u6d4b\uff0c\u4e24\u79cd\u68c0\u6d4b\u5747\u662f\u4e3a\u4e86\u51c6\u786e\u53cd\u6620\u6837\u54c1\u7684\u7eaf\u5ea6\u3002\u5b9a\u91cf\u8bd5\u9a8c\u6240\u9700\u9a8c\u8bc1\u9879\u76ee\u4e0e\u9650\u5ea6\u8bd5\u9a8c\u76f8\u6bd4\u662f\u4e0d\u540c\u7684\u3002<\/span>
\u2462 <\/span>\u542b\u91cf\u6d4b\u5b9a\u662f\u6307\u6d4b\u5b9a\u6837\u54c1\u4e2d\u88ab\u5206\u6790\u7269\u7684\u542b\u91cf\u3002\u672c\u6587\u4ef6\u4e2d\u542b\u91cf\u6d4b\u5b9a\u662f\u6307\u539f\u6599\u836f\u4e2d\u4e3b\u8981\u6210\u5206\u7684\u5b9a\u91cf\u6d4b\u5b9a\u3002\u7c7b\u4f3c\u7684\u9a8c\u8bc1\u9879\u76ee\u4e5f\u9002\u7528\u4e8e\u5236\u5242\u4e2d\u7684\u6d3b\u6027\u7ec4\u5206\u6216\u5176\u4ed6\u6307\u5b9a\u6210\u5206\u7684\u5b9a\u91cf\u6d4b\u5b9a\uff0c\u4ee5\u53ca\u4e0e\u5176\u4ed6\u5206\u6790\u65b9\u6cd5\uff08\u5982\u6eb6\u51fa\u5ea6\uff09\u76f8\u5173\u7684\u5b9a\u91cf\u5206\u6790\u3002<\/span><\/span><\/p>\n

3. \u5e94\u6e05\u695a\u4e86\u89e3\u5206\u6790\u65b9\u6cd5\u7684\u76ee\u7684\uff0c\u56e0\u4e3a\u8fd9\u5c06\u51b3\u5b9a\u9700\u8981\u8bc4\u4ef7\u54ea\u4e9b\u9a8c\u8bc1\u9879\u76ee\u3002\u5e94\u8fdb\u884c\u8bc4\u4ef7\u7684\u5178\u578b\u7684\u9a8c\u8bc1\u9879\u76ee\u5982\u4e0b\uff1a\u4e13\u5c5e\u6027\u3001\u68c0\u6d4b\u9650\u3001\u5b9a\u91cf\u9650\u3001\u7ebf\u6027\u4e0e\u8303\u56f4\u3001\u7cbe\u5bc6\u5ea6\uff08\u8fdb\u6837\u7cbe\u5bc6\u5ea6\u3001\u91cd\u590d\u6027\u3001\u4e2d\u95f4\u7cbe\u5bc6\u5ea6\uff09\u3001\u51c6\u786e\u6027\u3002<\/span><\/p>\n


<\/p>\n

\u4e8c\u3001\u54ea\u4e9b\u60c5\u51b5\u9700\u91cd\u65b0\u9a8c\u8bc1<\/span><\/strong><\/span>
\u2460 \u539f\u6599\u836f\u5408\u6210\u65b9\u6cd5\u7684\u6539\u53d8<\/span>
\u2461 <\/span>\u6210\u54c1\u7ec4\u5206\u53d1\u751f\u6539\u53d8<\/span>
\u2462 <\/span>\u5206\u6790\u65b9\u6cd5\u7684\u6539\u53d8<\/span>
<\/span><\/p>\n

\u9700\u8981\u91cd\u65b0\u9a8c\u8bc1\u7684\u7a0b\u5ea6\uff0c\u5e94\u6839\u636e\u6539\u53d8\u7684\u60c5\u51b5\u800c\u5b9a\u3002\u67d0\u4e9b\u5176\u4ed6\u7684\u6539\u53d8\u53ef\u80fd\u4e5f\u8981\u6c42\u9a8c\u8bc1\u3002<\/span><\/span><\/p>\n

\"\u786c\u8d27\uff01\u6df1\u5ea6\u89e3\u8bfb\u5206\u6790\u65b9\u6cd5\u5b66\u9a8c\u8bc1\u5404\u9879\u5173\u952e\u6307\u6807\u8981\u6c42\"<\/p>\n

\n

\u6ce8\u610f\uff1a-\u8868\u793a\u8be5\u9879\u76ee\u901a\u5e38\u4e0d\u9700\u8bc4\u4ef7
          +\u8868\u793a\u8be5\u9879\u76ee\u901a\u5e38\u9700\u8bc4\u4ef7
(1) \u5047\u5982\u5df2\u8bc4\u4ef7\u91cd\u73b0\u6027\uff08\u89c1\u672f\u8bed\u8868\uff09\uff0c\u53ef\u4e0d\u9700\u518d\u8bc4\u4ef7\u4e2d\u95f4\u7cbe\u5bc6\u5ea6\uff1b
(2) \u7f3a\u4e4f\u4e13\u5c5e\u6027\u7684\u5206\u6790\u65b9\u6cd5\uff0c\u5e94\u7531\u5176\u4ed6\u5206\u6790\u65b9\u6cd5\u6765\u505a\u8865\u5145\uff1b
(3) \u6709\u4e9b\u60c5\u51b5\u4e0b\u9700\u8981\u3002<\/span><\/p>\n

\n

\u4e09\u3001\u5206\u6790\u65b9\u6cd5\u5b66\u9a8c\u8bc1\u5404\u9879\u76ee\u7684\u5b9a\u4e49\u53ca\u5176\u8981\u6c42<\/span><\/strong><\/span><\/p>\n

1. <\/span><\/span>\u4e13\u5c5e\u6027<\/span>\uff08<\/span>Specificity<\/span>\uff09<\/span><\/span><\/strong><\/span>\u4e13\u5c5e\u6027\u662f\u6307\u53ef\u80fd\u5b58\u5728\u67d0\u4e9b\u7ec4\u5206(\u5982\u6742\u8d28\u3001\u964d\u89e3\u7269\u3001\u57fa\u8d28\u7b49)\u65f6\uff0c\u5bf9\u88ab\u5206\u6790\u7269\u51c6\u786e\u53ef\u9760\u6d4b\u5b9a\u7684\u80fd\u529b\u3002<\/span><\/p>\n

\u4e13\u5c5e\u6027\u6709\u4ee5\u4e0b\u542b\u4e49\uff1a<\/span>
\u2460 \u9274\u522b\uff1a\u786e\u8bc1\u88ab\u5206\u6790\u7269\u7b26\u5408\u5176\u7279\u6027\u3002<\/span>
\u2461 \u7eaf\u5ea6\u68c0\u67e5\uff1a\u786e\u4fdd\u91c7\u7528\u7684\u5206\u6790\u65b9\u6cd5\u53ef\u68c0\u51fa\u88ab\u5206\u6790\u7269\u4e2d\u6742\u8d28\u7684\u51c6\u786e\u542b\u91cf\uff0c\u5982\u6709\u5173\u7269\u8d28\u3001\u91cd\u91d1\u5c5e\u3001\u6eb6\u5242\u6b8b\u7559\u91cf\u7b49\u3002<\/span>
\u2462 \u542b\u91cf\u6d4b\u5b9a\uff08\u542b\u91cf\u6216\u6548\u4ef7\uff09\uff1a\u63d0\u4f9b\u6837\u54c1\u4e2d\u88ab\u5206\u6790\u7269\u7684\u542b\u91cf\u6216\u6548\u4ef7\u7684\u51c6\u786e\u7ed3\u679c\u3002<\/span><\/span><\/p>\n

\u4e13\u5c5e\u6027\u6ce8\u610f\u4e8b\u9879\uff1a<\/span><\/p>\n

\"\u786c\u8d27\uff01\u6df1\u5ea6\u89e3\u8bfb\u5206\u6790\u65b9\u6cd5\u5b66\u9a8c\u8bc1\u5404\u9879\u5173\u952e\u6307\u6807\u8981\u6c42\"<\/p>\n

\"\u786c\u8d27\uff01\u6df1\u5ea6\u89e3\u8bfb\u5206\u6790\u65b9\u6cd5\u5b66\u9a8c\u8bc1\u5404\u9879\u5173\u952e\u6307\u6807\u8981\u6c42\"<\/p>\n


<\/p>\n

(1) \u5b9a\u4f4d\u5206\u79bb\u8bd5\u9a8c<\/span><\/strong><\/span><\/p>\n

\u2460 \u4e3b\u5cf0\u5cf0\u7eaf\u5ea6\u7684\u786e\u5b9a<\/span><\/p>\n

\u5728\u4e13\u5c5e\u6027\u9a8c\u8bc1\u7684\u76f8\u5173\u5b9e\u9a8c\u4e2d\uff0c\u4e3b\u6210\u5206\u5cf0\u90fd\u5e94\u8be5\u8003\u5bdf\u5cf0\u7eaf\u5ea6\uff0c\u786e\u8ba4\u4e3b\u6210\u5206\u5cf0\u4e3a\u5355\u4e00\u6210\u5206\u7684\u5cf0\u3002\u5177\u4f53\u505a\u6cd5\u662f\u7528DAD\u68c0\u6d4b\u5668\u8fdb\u884c\u5cf0\u7eaf\u5ea6\u626b\u63cf\u6216\u8005\u7528LC-MS\u786e\u8ba4\u6ca1\u6709\u5176\u4ed6\u6210\u5206\u3002<\/span><\/p>\n

\u2461 \u7a00\u91ca\u5242<\/span><\/p>\n

\u5e94\u8003\u5bdf\u7a00\u91ca\u5242\u5bf9\u88ab\u6d4b\u7269\u7684\u5e72\u6270\uff0c\u7a7a\u767d\u7a00\u91ca\u5242\u51fa\u7684\u5cf0\u5e94\u4e0d\u5e72\u6270\u88ab\u6d4b\u7269\u3002\u5177\u4f53\u505a\u6cd5\u662f\u6309\u7167\u8d28\u91cf\u6807\u51c6\u89c4\u5b9a\u7684\u8fdb\u6837\u91cf\u8fdb\u6837\u7a7a\u767d\u7a00\u91ca\u5242\uff0c\u8bb0\u5f55\u8272\u8c31\u56fe\u3002<\/span><\/p>\n

\u2462 \u8f85\u6599<\/span><\/p>\n

\u53d6\u8d28\u91cf\u6807\u51c6\u89c4\u5b9a\u91cf\u7684\u4f9b\u8bd5\u54c1\u4e2d\u7b49\u91cf\u7684\u7a7a\u767d\u8f85\u6599\uff0c\u6309\u7167\u89c4\u5b9a\u5206\u6790\u5904\u7406\uff0c\u8bb0\u5f55\u8272\u8c31\u56fe\uff0c\u7a7a\u767d\u8f85\u6599\u5cf0\u5e94\u4e0d\u5e72\u6270\u88ab\u6d4b\u7269\u3002<\/span><\/p>\n

\u2463 \u6709\u5173\u7269\u8d28<\/span><\/p>\n

\u6709\u5173\u7269\u8d28\u5206\u4e3a\u4e24\u5927\u5757\uff1a\u5de5\u827a\u6742\u8d28\u548c\u964d\u89e3\u6742\u8d28\u3002\u5982\u679c\u5728\u4e8c\u8005\u5747\u53ef\u83b7\u5f97\u7684\u60c5\u51b5\u4e0b\uff0c\u5c06\u6742\u8d28\u5206\u522b\u5b9a\u4f4d\uff0c\u5e76\u914d\u5236\u4e00\u4efd\u6df7\u5408\u6eb6\u6db2\uff0c\u6839\u636e\u68c0\u6d4b\u5185\u5bb9\u7684\u4e0d\u540c\u5206\u522b\u7814\u7a76\u3002\u542b\u91cf\u6d4b\u5b9a\u5404\u6742\u8d28\u5cf0\u5e94\u4e0d\u5e72\u6270\u4e3b\u6210\u5206\u7684\u68c0\u6d4b\uff0c\u5373\u5404\u6742\u8d28\u5cf0\u5e94\u548c\u4e3b\u6210\u5206\u5cf0\u8fbe\u6210\u57fa\u7ebf\u5206\u79bb\uff0c\u5404\u6742\u8d28\u5cf0\u4e4b\u95f4\u6ca1\u6709\u8981\u6c42\uff0c\u91cd\u53e0\u4e5f\u65e0\u59a8\uff0c\u56e0\u4e3a\u542b\u91cf\u6d4b\u5b9a\u53ea\u9700\u786e\u8ba4\u4e3b\u6210\u5206\u5cf0\u4e0d\u53d7\u5e72\u6270\u5373\u53ef\u3002\u6709\u5173\u7269\u8d28\u4e2d\u5404\u6742\u8d28\u5cf0\u548c\u4e3b\u6210\u5206\u5cf0\u4e4b\u95f4\u7684\u5206\u79bb\u5ea6\u5747\u5e94\u7b26\u5408\u8981\u6c42\uff0c\u4e00\u822c\u4e0d\u5c0f\u4e8e1.5\u3002\u7279\u6b8a\u60c5\u51b5\u53ef\u5c06\u67d0\u4e9b\u6742\u8d28\u5408\u5e76\u63a7\u5236\uff0c\u5982\u4e92\u4e3a\u5bf9\u6620\u5f02\u6784\u4f53\u7684\u975e\u5bf9\u6620\u5f02\u6784\u4f53\uff0c\u5b83\u4eec\u5728\u53cd\u76f8\u8272\u8c31\u6cd5\u4e2d\u4e00\u822c\u90fd\u662f\u91cd\u53e0\u7684\u5cf0\u3002<\/span><\/p>\n

\u5982\u964d\u89e3\u6742\u8d28\u4e0d\u53ef\u83b7\u5f97\uff0c\u5e94\u8fdb\u884c\u9178\u78b1\u6c27\u5316\u7834\u574f\u6761\u4ef6\u4e0b\u8003\u5bdf\u53ef\u80fd\u7684\u964d\u89e3\u6742\u8d28\u7684\u5e72\u6270\uff0c\u8be5\u5b9e\u9a8c\u4e00\u822c\u90fd\u505a\uff0c\u4f46\u4e0d\u662f\u5fc5\u987b\u505a\uff0c\u5982\u679c\u5df2\u7ecf\u5bf9\u964d\u89e3\u6742\u8d28\u6709\u4e86\u5145\u5206\u7684\u7814\u7a76\uff0c\u5c31\u65e0\u9700\u505a\u7834\u574f\u5b9e\u9a8c\u3002\u4f8b\u5982\u5df2\u7ecf\u6709\u4e86\u6709\u6548\u671f\u5185\u957f\u671f\u7a33\u5b9a\u6027\u7684\u7814\u7a76\u7ed3\u679c\uff0c\u786e\u8ba4\u4e86\u7a33\u5b9a\u6027\u671f\u95f4\u7684\u5b9e\u9645\u964d\u89e3\u6742\u8d28\u3002\u56e0\u4e3a\u6709\u4e9b\u60c5\u51b5\u4e0b\uff0c\u7834\u574f\u5b9e\u9a8c\u7684\u7ed3\u679c\u4e0d\u662f\u771f\u5b9e\u53ef\u80fd\u7684\u964d\u89e3\u6742\u8d28\uff0c\u8fd9\u79cd\u60c5\u51b5\u4ee5\u53cc\u6c27\u6c34\u8fdb\u884c\u6c27\u5316\u7834\u574f\u6700\u4e3a\u5e38\u89c1\uff0c\u7834\u574f\u4ea7\u7269\u6742\u4e71\u65e0\u7ae0\uff0c\u751a\u81f3\u6709\u53ef\u80fd\u56e0\u4e3a\u8be5\u5b9e\u9a8c\u63a8\u7ffb\u5206\u6790\u65b9\u6cd5\u3002<\/span><\/p>\n

\n

(2) \u5f3a\u5236\u964d\u89e3\u8bd5\u9a8c<\/span><\/strong><\/span><\/p>\n

\u53d6\u672c\u54c1\u5206\u522b\u5728\u4ee5\u4e0b\u6761\u4ef6\u8fdb\u884c\u7834\u574f\u964d\u89e3\u8bd5\u9a8c\uff1a<\/span><\/p>\n

\"\u786c\u8d27\uff01\u6df1\u5ea6\u89e3\u8bfb\u5206\u6790\u65b9\u6cd5\u5b66\u9a8c\u8bc1\u5404\u9879\u5173\u952e\u6307\u6807\u8981\u6c42\"<\/p>\n

\u6ce8\u610f\uff1a\u9178\u3001\u78b1\u548c\u53cc\u6c27\u6c34\u6eb6\u6db2\u6d53\u5ea6\u548c\u653e\u7f6e\u65f6\u95f4\u5747\u53ef\u4ee5\u6839\u636e\u7834\u574f\u60c5\u51b5\u8fdb\u884c\u8c03\u6574\uff0c\u5982\u67d0\u4e2a\u6761\u4ef6\u6709\u964d\u89e3\u503e\u5411\uff0c\u5e94\u8c03\u8282\u6761\u4ef6\u4f7f\u7834\u574f\u81f35%-20%\u4e4b\u95f4\u3002\u5982\u4e09\u8005\u5747\u672a\u53d1\u73b0\u964d\u89e3\u503e\u5411\uff0c\u518d\u653e\u7f6e\u4e00\u6bb5\u65f6\u95f4\u598210\u5929\uff0c\u4f9d\u7136\u5982\u6b64\uff0c\u65e2\u53ef\u8bf4\u660e\u672c\u5316\u5408\u7269\u975e\u5e38\u7a33\u5b9a\uff0c\u7a33\u5b9a\u6027\u671f\u95f4\u5e94\u4e0d\u4f1a\u4ea7\u751f\u964d\u89e3\u6742\u8d28\u3002<\/span>
<\/p>\n

\n

\u2460 \u5cf0\u7eaf\u5ea6<\/span><\/p>\n

\u5404\u6761\u4ef6\u4e0b\u7684\u5cf0\u7eaf\u5ea6\u5e94\u7b26\u5408\u8981\u6c42\u3002<\/span><\/p>\n

\n

\u2461 \u5206\u79bb\u5ea6<\/span>
<\/p>\n

\u542b\u91cf\u6d4b\u5b9a\u65b9\u6cd5\u5404\u7834\u574f\u4ea7\u7269\u5e94\u4e0e\u4e3b\u6210\u5206\u8fbe\u6210\u57fa\u7ebf\u5206\u79bb\uff0c\u6709\u5173\u7269\u8d28\u65b9\u6cd5\u5404\u7834\u574f\u4ea7\u7269\u4e0e\u4e3b\u6210\u5206\u4e4b\u95f4\u7684\u5206\u79bb\u5ea6\u5747\u5e94\u4e0d\u5c0f\u4e8e1.5\uff0c\u5404\u6742\u8d28\u4e4b\u95f4\u7684\u5206\u79bb\u5ea6\u5747\u5e94\u4e0d\u5c0f\u4e8e1.0\u3002<\/span><\/p>\n

\n

\u2462 \u8d28\u91cf\u5b88\u6052<\/span>
<\/p>\n

\u6709\u5173\u7269\u8d28\u68c0\u6d4b\u65b9\u6cd5\u9700\u8981\u505a\u8d28\u91cf\u5b88\u6052\u7684\u9a8c\u7b97\uff0c\u5e94\u8bc4\u4f30\u4e3b\u6210\u5206\u51cf\u5c11\u7684\u91cf\u4e0e\u6742\u8d28\u589e\u52a0\u7684\u91cf\u7684\u4e00\u81f4\u6027\u3002\u7406\u8bba\u4e0a\u5982\u4e3b\u6210\u5206\u51cf\u5c1110%\uff0c\u6742\u8d28\u5e94\u589e\u52a010%\uff0c\u624d\u80fd\u8bf4\u660e\u6709\u5173\u7269\u8d28\u65b9\u6cd5\u80fd\u51c6\u786e\u68c0\u51fa\u6240\u6709\u7684\u964d\u89e3\u6742\u8d28\u3002\u5982\u4e8c\u8005\u4e0d\u4e00\u81f4\uff0c\u5219\u8bc1\u660e\u65b9\u6cd5\u6709\u7f3a\u9677\uff0c\u6216\u4e3a\u964d\u89e3\u6742\u8d28\u672a\u68c0\u51fa\uff0c\u6216\u4e3a\u964d\u89e3\u6742\u8d28\u7814\u7a76\u4e0d\u5145\u5206\uff0c\u56e0\u4e3a\u6ca1\u6709\u83b7\u5f97\u4e3b\u8981\u964d\u89e3\u6742\u8d28\u7684\u5bf9\u7167\u54c1\uff0c\u4e0d\u6e05\u695a\u4e3b\u8981\u964d\u89e3\u6742\u8d28\u7684\u6821\u6b63\u56e0\u5b50\u3002<\/span><\/p>\n

\n

\u2463 \u8d28\u91cf\u5b88\u6052\u8ba1\u7b97\u65b9\u6cd5<\/span>
<\/p>\n

\u5982\u4e3b\u6210\u5206\u5cf0\u5728\u7ebf\u6027\u8303\u56f4\u5185\uff0c\u53ef\u5c06\u4f9b\u8bd5\u54c1\u6eb6\u6db2\u7684\u4e3b\u5cf0\u5cf0\u9762\u79ef\u548c\u6821\u6b63\u540e\u7684\u603b\u6742\u8d28\u5cf0\u9762\u79ef\u4e4b\u548cA\u9664\u4ee5\u4e0e\u7834\u574f\u540e\u7684\u6eb6\u6db2\u4e3b\u5cf0\u5cf0\u9762\u79ef\u548c\u6821\u6b63\u540e\u7684\u603b\u6742\u8d28\u5cf0\u9762\u79ef\u4e4b\u548cA\u7834\uff0c\u5176\u9650\u5ea6\u5e94\u572898%-102%\u4e4b\u95f4\u3002\u5373A\u4f9b\/A\u7834\u7684\u503c\u5e94\u572898%-102%\u4e4b\u95f4\u3002\u5236\u5b9a\u6b64\u9650\u5ea6\u7684\u4f9d\u636e\u662f\u836f\u5178\u6db2\u76f8\u7cfb\u7edf\u9002\u7528\u6027\u5b9e\u9a8c\u8fde\u7eed\u8fdb\u68375\u9488\uff0c\u5141\u8bb8RSD\u4e0d\u5927\u4e8e2%\uff0c\u4e5f\u5373\u6570\u636e2%\u4ee5\u5185\u7684\u8bef\u5dee\u53ef\u4ee5\u5f52\u5c5e\u4e3a\u4eea\u5668\u5f15\u5165\u3002<\/span><\/p>\n

 <\/span>\u5982\u4e3b\u6210\u5206\u4e0d\u5728\u7ebf\u6027\u8303\u56f4\u5185\uff0c\u5219\u53ef\u6d4b\u5b9a\u4f9b\u8bd5\u54c1\u6eb6\u6db2\u548c\u7834\u574f\u540e\u7684\u6eb6\u6db2\u7684\u4e3b\u6210\u5206\u542b\u91cf\u548c\u6709\u5173\u7269\u8d28\uff0c\u542b\u91cf\u51cf\u5c11\u503c\u9664\u4ee5\u6709\u5173\u7269\u8d28\u589e\u52a0\u503c\uff0c\u9650\u5ea6\u5e94\u5728<\/span>90%-110%<\/span>\u4e4b\u95f4\u3002\u5236\u5b9a\u8fd9\u4e2a\u4f9d\u636e\u6e90\u81ea\u6821\u6b63\u56e0\u5b50<\/span>0.9-1.1<\/span>\u4e4b\u95f4\u90fd\u53ef\u4e0d\u52a0\u6821\u6b63\u56e0\u5b50\u8ba1\u7b97\u6709\u5173\u7269\u8d28\uff0c\u8868\u660e\u6742\u8d28\u7ed3\u679c\u5141\u8bb8<\/span>10%<\/span>\u7684\u8bef\u5dee\u3002<\/span><\/p>\n

 <\/span>\u4ee5\u4e0a\u4e24\u4e2a\u9650\u5ea6\u975e\u5b98\u65b9\u89c4\u5b9a\uff0c\u4e3a\u5408\u7406\u9650\u5ea6\uff0c\u4ec5\u4f9b\u53c2\u8003\uff0c\u5b9e\u9645\u5de5\u4f5c\u4e2d\u53ef\u6839\u636e\u60c5\u51b5\u8fdb\u884c\u8c03\u6574\uff0c\u672c\u6587\u4e2d\u6d89\u53ca\u7684\u5927\u90e8\u5206\u6570\u5b57\u90fd\u662f\u5982\u6b64\u3002<\/span><\/p>\n

\n

\u2464 \u5982\u4f55\u786e\u5b9a\u54ea\u4e2a\u964d\u89e3\u4ea7\u7269\u9700\u8981\u8fdb\u884c\u9274\u5b9a\uff1f<\/span><\/p>\n

\u5efa\u8bae\u5728\u6bcf\u4e2a\u5f3a\u5236\u6761\u4ef6\u4e0b\u964d\u89e3\u7684\u4e3b\u8981\u964d\u89e3\u4ea7\u7269\u8fdb\u884c\u9274\u5b9a\uff0c\u4e00\u4e2a\u201c\u7ecf\u9a8c\u89c4\u5219\u201d\u662f\u5bf9\u8d85\u8fc7\u603b\u964d\u89e3\u4ea7\u726910%\u7684\u7269\u8d28\u8fdb\u884c\u9274\u5b9a\uff0c\u56e0\u6b64\uff0c\u5982\u679c\u836f\u7269\u964d\u89e310%\uff0c\u5355\u4e2a\u964d\u89e3\u4ea7\u7269\u76f8\u5bf9\u4e3b\u836f\u964d\u89e33%\uff0c\u5360\u603b\u964d\u89e3\u4ea7\u7269\u768430%\uff0c\u8fd9\u4e2a\u964d\u89e3\u4ea7\u7269\u9700\u9274\u5b9a\uff0c\u6216\u8005\uff0c\u5982\u679c\u836f\u7269\u964d\u89e310%\uff0c\u5355\u4e2a\u964d\u89e3\u4ea7\u7269\u76f8\u5bf9\u4e3b\u836f\u964d\u89e30.8%\uff0c\u4ec5\u5360\u603b\u964d\u89e3\u4ea7\u7269\u76848%\uff0c\u8fd9\u4e2a\u964d\u89e3\u4ea7\u7269\u4e0d\u9700\u9274\u5b9a\uff0c\u89c1PhRMA\u7684\u201c\u73b0\u6709\u6307\u5bfc\u548c\u6700\u4f73\u5b9e\u8df5\u201d\u7b49\u6587\u732e\uff0c\u6700\u8fd1PhRMA\u767d\u76ae\u4e66\u6587\u4ef6\u63d0\u51fa\u4e86\u7c7b\u4f3c\u65b9\u6cd5\u4f5c\u4e3a\u786e\u5b9a\u5f3a\u5236\u964d\u89e3\u8bd5\u9a8c\u4e2d\u4ea7\u751f\u7684\u964d\u89e3\u4ea7\u7269\u8fdb\u884c\u7ed3\u6784\u9274\u5b9a\u7684\u7b97\u6cd5\uff0c\u8be5\u767d\u76ae\u4e66\u7ed3\u5408ICHQ3A \u548cQ3B\u4e2d\u7684\u9274\u5b9a\u9650\u7ed9\u51fa\u4e86\u5f3a\u5236\u964d\u89e3\u8bd5\u9a8c\u4e2d\u964d\u89e3\u4ea7\u7269\u7684\u9274\u5b9a\u9650\u3002\u89c1\u4e0b\u8868\uff1a<\/span><\/p>\n


<\/p>\n

\u2465 \u8865\u5145\u8bf4\u660e<\/span><\/p>\n

\u964d\u89e3\u5b9e\u9a8c\u53ef\u4ee5\u6709\u5173\u7269\u8d28\u548c\u542b\u91cf\u6d4b\u5b9a\u540c\u65f6\u505a\uff0c\u4e8c\u8005\u53ef\u4ee5\u5171\u7528\u540c\u4e00\u4efd\u7834\u574f\u6837\u54c1\uff0c\u51cf\u5c11\u5de5\u4f5c\u91cf\uff0c\u4e00\u822c\u6765\u8bf4\u6709\u5173\u7269\u8d28\u7684\u4f9b\u8bd5\u54c1\u6d53\u5ea6\u5927\u4e8e\u542b\u91cf\u6d4b\u5b9a\uff0c\u53ef\u4ee5\u5c06\u6709\u5173\u7269\u8d28\u7834\u574f\u540e\u7684\u6eb6\u6db2\u7a00\u91ca\u81f3\u542b\u91cf\u6d4b\u5b9a\u89c4\u5b9a\u6d53\u5ea6\u3002\u5177\u4f53\u5982\u4f55\u64cd\u4f5c\u8bf7\u8bfb\u8005\u8bf8\u541b\u81ea\u5df1\u8bbe\u8ba1\u3002<\/span><\/p>\n

\n

2. \u68c0\u6d4b\u9650\uff08Detectionlimit\uff09<\/span><\/strong><\/span><\/p>\n

\u67d0\u4e00\u5206\u6790\u65b9\u6cd5\u7684\u68c0\u6d4b\u9650\u5ea6\u662f\u6307\u6837\u54c1\u4e2d\u7684\u88ab\u5206\u6790\u7269\u80fd\u591f\u88ab\u68c0\u6d4b\u5230\u7684\u6700\u4f4e\u91cf\uff0c\u4f46\u4e0d\u4e00\u5b9a\u8981\u51c6\u786e\u5b9a\u91cf\u3002<\/span><\/p>\n

\u68c0\u6d4b\u9650\u6ce8\u610f\u4e8b\u9879\uff1a<\/span><\/p>\n

\"\u786c\u8d27\uff01\u6df1\u5ea6\u89e3\u8bfb\u5206\u6790\u65b9\u6cd5\u5b66\u9a8c\u8bc1\u5404\u9879\u5173\u952e\u6307\u6807\u8981\u6c42\"<\/p>\n

\u68c0\u6d4b\u9650\u6eb6\u6db2\u53ef\u4ee5\u7531\u6bcd\u6db2\u7a00\u91ca\u76f4\u63a5\u8003\u5bdf\u4fe1\u566a\u6bd4\uff0c\u57282-4\u8303\u56f4\u5185\u5373\u53ef\u3002\u4e5f\u53ef\u7531\u516c\u5f0fLOD=3.3\u00d7STEYX\/\u659c\u7387\u8ba1\u7b97\u5f97\u51fa\u68c0\u6d4b\u9879\u6d53\u5ea6\u3002<\/span>
<\/p>\n

\n

3. \u5b9a\u91cf\u9650\uff08Quantitationlimit\uff09<\/span><\/strong><\/span><\/p>\n

\u5b9a\u91cf\u9650\u5ea6\u662f\u6307\u5728\u5408\u9002\u7684\u51c6\u786e\u6027\u548c\u7cbe\u5bc6\u5ea6\u4e0b\uff0c\u80fd\u591f\u5b9a\u91cf\u6d4b\u5b9a\u6837\u54c1\u4e2d\u88ab\u5206\u6790\u7269\u7684\u6700\u4f4e\u91cf\u3002\u5b83\u662f\u6837\u54c1\u4e2d\u542b\u91cf\u4f4e\u7684\u5316\u5408\u7269\u5b9a\u91cf\u6d4b\u5b9a\u7684\u53c2\u6570\uff0c\u7279\u522b\u9002\u7528\u4e8e\u6742\u8d28\u548c\/\u6216\u964d\u89e3\u4ea7\u7269\u7684\u6d4b\u5b9a\u3002<\/span><\/p>\n

\u5b9a\u91cf\u9650\u6ce8\u610f\u4e8b\u9879\uff1a<\/span><\/p>\n

\"\u786c\u8d27\uff01\u6df1\u5ea6\u89e3\u8bfb\u5206\u6790\u65b9\u6cd5\u5b66\u9a8c\u8bc1\u5404\u9879\u5173\u952e\u6307\u6807\u8981\u6c42\"<\/p>\n

\u5176\u6d4b\u5b9a\u7ed3\u679c\u5e94\u5177\u6709\u4e00\u5b9a\u7684\u51c6\u786e\u5ea6\u548c\u7cbe\u5bc6\u5ea6\u3002\u4ece\u8fd9\u4e00\u6982\u5ff5\u51fa\u53d1\uff0c\u5e94\u786e\u5b9a\u4fe1\u566a\u6bd4\u4e3a10\u7684\u4f9b\u8bd5\u54c1\u7684\u6d53\u5ea6\u662f\u7406\u6240\u5f53\u7136\u7684\u3002\u7136\u800c\u54cd\u5e94\u60c5\u51b5\u968f\u7740\u4eea\u5668\u4e0e\u6d41\u52a8\u76f8\u7684\u4e0d\u540c\u800c\u4e0d\u540c\uff0c\u5728\u65b9\u6cd5\u9a8c\u8bc1\u65f6\u6240\u9009\u4eea\u5668\u4e0e\u6d41\u52a8\u76f8\u5f97\u51fa\u7684\u4fe1\u566a\u6bd4\u4e3a10\u7684\u4f9b\u8bd5\u54c1\u7684\u6d53\u5ea6\u4e0d\u5177\u6709\u666e\u904d\u610f\u4e49\u4e0a\u7684\u4ee3\u8868\u6027\uff0c\u8fd9\u53ea\u662f\u4e00\u4e2a\u5076\u7136\u503c\u3002\u6211\u4eec\u5728\u5b9e\u9645\u5de5\u4f5c\u4e2d\u5176\u5b9e\u65e0\u9700\u786e\u5b9a\u4fe1\u566a\u6bd4\u4e3a10\u7684\u4f9b\u8bd5\u54c1\u7684\u6d53\u5ea6\uff0c\u53ea\u9700\u8bc1\u660e\u65b9\u6cd5\u9700\u5b9a\u91cf\u7684\u9650\u5ea6\u7684\u5408\u7406\u6027\u3002\u4ee5\u4e0b\u4e3e\u4f8b\u8bf4\u660e\uff1a\u82e5\u65b9\u6cd5\u62a5\u544a\u9650\u89c4\u5b9a\u4e3a0.05%\uff0c\u90a3\u4e48\u80af\u5b9a\u9700\u8981\u8bc1\u660e\u6b64\u9650\u5ea6\u80fd\u51c6\u786e\u5b9a\u91cf\uff0c\u5982\u4e0d\u80fd\u51c6\u786e\u5b9a\u91cf\uff0c\u5219\u6b64\u9879\u89c4\u5b9a\u4e0d\u5408\u7406\u3002\u6211\u4eec\u53ef\u4ee5\u7a00\u91ca\u5236\u62100.01%\u7684\u76f8\u5e94\u6eb6\u6db2\uff0c\u6ce8\u5165\u4eea\u5668\u68c0\u6d4b\uff0c\u5176\u4fe1\u566a\u6bd4\u5982\u5927\u4e8e10\uff0c\u5219\u8bc1\u660e\u65b9\u6cd5\u6709\u5408\u7406\u7684\u5b9a\u91cf\u9650\u3002\u65e0\u9700\u8d39\u65f6\u8d39\u529b\u627e\u51fa\u6bcf\u4e2a\u6742\u8d28\u7684\u4fe1\u566a\u6bd410\u7684\u6d53\u5ea6\uff0c\u7279\u522b\u662f\u5df2\u77e5\u6742\u8d28\u6570\u91cf\u8f83\u591a\u7684\u60c5\u51b5\u4e0b\uff0c\u5de5\u4f5c\u91cf\u5c06\u6781\u4e3a\u5de8\u5927\u3002\u76f4\u63a5\u7a00\u91ca\u81f3\u7279\u5b9a\u6d53\u5ea6\u8003\u5bdf\u4fe1\u566a\u6bd4\uff0c\u5219\u975e\u5e38\u7b80\u5355\uff0c\u53ea\u9700\u5c06\u7ebf\u6027\u9a8c\u8bc1\u9879\u4e0b\u7684\u6df7\u5408\u6742\u8d28\u6eb6\u6db2\u7a00\u91ca\u81f3\u76ee\u6807\u6d53\u5ea6\u5373\u53ef\u3002<\/span>
<\/p>\n

 <\/span><\/p>\n

\u8fd8\u6709\u4e00\u79cd\u7b80\u5355\u7684\u8ba1\u7b97LOQ\u7684\u65b9\u6cd5\u5c31\u662f\u6839\u636e\u7ebf\u6027\u9a8c\u8bc1\u7684\u7ed3\u679c\u8ba1\u7b97\uff0c\u516c\u5f0f\u4e3aLOQ=10\u00d7STEYX\/\u659c\u7387\uff0cSTEYX\u4e3a\u7ebf\u6027\u6570\u636e\u7684\u5269\u4f59\u6807\u51c6\u504f\u5dee\uff0c\u53ef\u4ee5\u7528EXCEL\u76f4\u63a5\u7b97\u51fa\u8fd9\u4e2a\u503c\u3002<\/span><\/p>\n

 <\/span><\/strong><\/p>\n

4. \u7cbe\u5bc6\u5ea6\uff08Precision\uff09<\/span><\/strong><\/span>
\u5206\u6790\u65b9\u6cd5\u7684\u7cbe\u5bc6\u5ea6\u6307\u7684\u662f\u89c4\u5b9a\u6761\u4ef6\u4e0b\u5bf9\u5747\u8d28\u6837\u54c1\u591a\u6b21\u53d6\u6837\u8fdb\u884c\u4e00\u7cfb\u5217\u68c0\u6d4b\u7ed3\u679c\u7684\u63a5\u8fd1\u7a0b\u5ea6\uff08\u79bb\u6563\u7a0b\u5ea6\uff09\u3002\u7cbe\u5bc6\u5ea6\u53ef\u4ee5\u4ece\u4e09\u4e2a\u5c42\u6b21\u8003\u8651\uff1a\u8fdb\u6837\u7cbe\u5bc6\u5ea6\u3001\u91cd\u590d\u6027\u3001\u4e2d\u95f4\u7cbe\u5bc6\u5ea6\u3002\u5206\u6790\u65b9\u6cd5\u7684\u7cbe\u5bc6\u5ea6\u901a\u5e38\u4ee5\u591a\u6b21\u6d4b\u91cf\u7ed3\u679c\u7684\u53d8\u5f02\u6027\u3001\u6807\u51c6\u504f\u5dee\u6216\u53d8\u5f02\u7cfb\u6570\u6765\u8868\u8fbe\u3002<\/span><\/p>\n

\n

4.1 \u8fdb\u6837\u7cbe\u5bc6\u5ea6<\/span><\/strong><\/span><\/p>\n

\u4e3b\u8981\u7528\u6765\u8003\u5bdf\u4eea\u5668\u8fdb\u6837\u5206\u6790\u7684\u7cbe\u5bc6\u7a0b\u5ea6\u3002<\/span><\/p>\n

\u8fdb\u6837\u7cbe\u5bc6\u5ea6\u6ce8\u610f\u4e8b\u9879\uff1a<\/span><\/p>\n

\"\u786c\u8d27\uff01\u6df1\u5ea6\u89e3\u8bfb\u5206\u6790\u65b9\u6cd5\u5b66\u9a8c\u8bc1\u5404\u9879\u5173\u952e\u6307\u6807\u8981\u6c42\"<\/p>\n


<\/p>\n


<\/p>\n

4.2 \u91cd\u590d\u6027\uff08Repeatability\uff09<\/span><\/strong><\/span><\/p>\n

\u91cd\u590d\u6027\u662f\u6307\u5728\u540c\u6837\u7684\u64cd\u4f5c\u6761\u4ef6\u4e0b\uff0c\u5728\u8f83\u77ed\u65f6\u95f4\u95f4\u9694\u7684\u7cbe\u5bc6\u5ea6\uff1a\u4e5f\u79f0\u4e3a\u6279\u5185\u7cbe\u5bc6\u5ea6\uff08Intra-assayprecision\uff09\u3002<\/span><\/p>\n

\u91cd\u590d\u6027\u6ce8\u610f\u4e8b\u9879\uff1a<\/span><\/p>\n

\"\u786c\u8d27\uff01\u6df1\u5ea6\u89e3\u8bfb\u5206\u6790\u65b9\u6cd5\u5b66\u9a8c\u8bc1\u5404\u9879\u5173\u952e\u6307\u6807\u8981\u6c42\"<\/p>\n


<\/p>\n


<\/p>\n

4.3 \u4e2d\u95f4\u7cbe\u5bc6\u5ea6\uff08Intermediate precision\uff09<\/span><\/strong><\/span><\/p>\n

\u4e2d\u95f4\u7cbe\u5bc6\u5ea6\u662f\u6307\u8bd5\u9a8c\u5ba4\u5185\u90e8\u6761\u4ef6\u6539\u53d8\uff0c\u5982\uff1a \u4e0d\u540c\u65e5\u3001\u4e0d\u540c\u5206\u6790\u8005\u3001\u4e0d\u540c\u4eea\u5668\u7b49\u60c5\u51b5\u4e0b\u7684\u7cbe\u5bc6\u5ea6\u3002<\/span><\/p>\n

\u4e2d\u95f4\u7cbe\u5bc6\u5ea6\u6ce8\u610f\u4e8b\u9879\uff1a<\/span><\/p>\n

\"\u786c\u8d27\uff01\u6df1\u5ea6\u89e3\u8bfb\u5206\u6790\u65b9\u6cd5\u5b66\u9a8c\u8bc1\u5404\u9879\u5173\u952e\u6307\u6807\u8981\u6c42\"<\/p>\n


<\/p>\n


<\/p>\n

5. \u7ebf\u6027\u4e0e\u8303\u56f4\uff08Linearity and Range\uff09<\/span><\/strong><\/span>
\u5206\u6790\u65b9\u6cd5\u7684\u7ebf\u6027\u662f\u6307\u5728\u7ed9\u5b9a\u7684\u8303\u56f4\u5185\u68c0\u6d4b\u7ed3\u679c\u4e0e\u6837\u54c1\u4e2d\u88ab\u5206\u6790\u7269\u7684\u6d53\u5ea6\uff08\u91cf\uff09\u6210\u6bd4\u4f8b\u5173\u7cfb\u7684\u80fd\u529b\u3002\u5206\u6790\u65b9\u6cd5\u7684\u8303\u56f4\u662f\u6307\u6837\u54c1\u4e2d\u88ab\u5206\u6790\u7269\u7684\u8f83\u9ad8\u6d53\u5ea6\uff08\u91cf\uff09\u548c\u8f83\u4f4e\u6d53\u5ea6\uff08\u91cf\uff09\u4e4b\u95f4\u7684\u4e00\u4e2a\u533a\u95f4\uff0c\u5e76\u5df2\u8bc1\u5b9e\u5728\u6b64\u533a\u95f4\u5185\uff0c\u8be5\u65b9\u6cd5\u5177\u6709\u5408\u9002\u7684\u51c6\u786e\u6027\u3001\u7cbe\u5bc6\u5ea6\u548c\u7ebf\u6027\u3002<\/span><\/p>\n

\u7ebf\u6027\u4e0e\u8303\u56f4\u6ce8\u610f\u4e8b\u9879\uff1a<\/span><\/p>\n

\"\u786c\u8d27\uff01\u6df1\u5ea6\u89e3\u8bfb\u5206\u6790\u65b9\u6cd5\u5b66\u9a8c\u8bc1\u5404\u9879\u5173\u952e\u6307\u6807\u8981\u6c42\"<\/p>\n

\u9700\u8981\u6ce8\u610f\u7684\u662f\u5728\u6709\u5173\u7269\u8d28\u7ebf\u6027\u9a8c\u8bc1\u4e2d\uff0c\u9664\u9762\u79ef\u5f52\u4e00\u6cd5\u4e4b\u5916\uff0c\u8303\u56f4\u4e0d\u5b9c\u592a\u5bbd\uff0c\u5426\u5219\u76f8\u5173\u7cfb\u6570\u8f83\u5dee\uff0c\u622a\u8ddd\u8f83\u5927\u3002\u5982\u679c\u6ce2\u957f\u8f83\u5c0f\uff0c\u63a5\u8fd1\u6d41\u52a8\u76f8\u622a\u6b62\u6ce2\u957f\uff0c\u5219\u6d41\u52a8\u76f8\u672c\u5e95\u5438\u6536\u8f83\u5927\uff0c\u5219\u66f4\u8981\u7f29\u5c0f\u7ebf\u6027\u9a8c\u8bc1\u7684\u8303\u56f4\u3002\u6bcf\u4e2a\u70b9\u5cf0\u9762\u79ef\u4e3a\u4f9b\u8bd5\u54c1\u5b9e\u9645\u7684\u54cd\u5e94\u503c\u51cf\u53bb\u6d41\u52a8\u76f8\u672c\u5e95\u503c\u3002\u65e5\u5e38\u5de5\u4f5c\u4e2d\u5e94\u8be5\u80fd\u53d1\u73b0\u5728\u9ad8\u6d41\u52a8\u76f8\u672c\u5e95\u5438\u6536\u7684\u4f4e\u6d53\u5ea6\u4e0b\u54cd\u5e94\u8fdc\u5c0f\u4e8e\u9ad8\u6d53\u5ea6\u54cd\u5e94\u9664\u4ee5\u76f8\u5e94\u7a00\u91ca\u500d\u6570\u7684\u503c\uff0c\u5c31\u662f\u7531\u4e8e\u6d41\u52a8\u76f8\u672c\u5e95\u7684\u5f71\u54cd\u3002\u4e00\u822c\u6709\u5173\u7269\u8d28\u7ebf\u6027\u8303\u56f4\u53ef\u4ee5\u662f\u9650\u5ea6\u768420%\u300150%\u300180%\u3001100%\u3001120%\u3001150%\u3002\u8fd8\u9700\u6ce8\u610f\u7684\u662f\u7ebf\u6027\u8303\u56f4\u5e94\u5305\u62ec\u51c6\u786e\u5ea6\u7684\u4e09\u4e2a\u503c\u3002<\/span>
<\/p>\n

\n

6. \u51c6\u786e\u5ea6\uff08Accuracy\uff09<\/span><\/strong><\/span><\/p>\n

\u5206\u6790\u65b9\u6cd5\u7684\u51c6\u786e\u6027\u6307\u7684\u662f\u771f\u5b9e\u503c\u6216\u8ba4\u53ef\u7684\u53c2\u8003\u503c\u4e0e\u6d4b\u91cf\u503c\u4e4b\u95f4\u76f8\u8fd1\u7a0b\u5ea6\u3002\u51c6\u786e\u6027\u6709\u65f6\u4e5f\u79f0\u771f\u5b9e\u5ea6\u3002<\/span><\/p>\n

\u51c6\u786e\u5ea6\u6ce8\u610f\u4e8b\u9879\uff1a<\/span><\/p>\n

\"\u786c\u8d27\uff01\u6df1\u5ea6\u89e3\u8bfb\u5206\u6790\u65b9\u6cd5\u5b66\u9a8c\u8bc1\u5404\u9879\u5173\u952e\u6307\u6807\u8981\u6c42\"<\/p>\n

\u6709\u5173\u7269\u8d28\u51c6\u786e\u5ea6\u7684\u6570\u636e\u5e94\u8be5\u6309\u7167\u8d28\u91cf\u6807\u51c6\u89c4\u5b9a\u5904\u7406\uff0c\u4f8b\u5982\u8d28\u91cf\u6807\u51c6\u89c4\u5b9a\u4e3a\u52a0\u6821\u6b63\u56e0\u5b50\u7684\u81ea\u8eab\u5bf9\u7167\u6cd5\uff0c\u5219\u5e94\u8be5\u6309\u7167\u8d28\u91cf\u6807\u51c6\u7684\u89c4\u5b9a\u8ba1\u7b97\u5404\u6837\u54c1\u6eb6\u6db2\u7684\u6742\u8d28\u542b\u91cf\uff0c\u5e76\u8ba1\u7b97\u56de\u6536\u7387\u3002\u5076\u89c1\u7528\u5916\u6807\u6cd5\u8ba1\u7b97\u6709\u5173\u7269\u8d28\u7684\u56de\u6536\u7387\uff0c\u800c\u8d28\u91cf\u6807\u51c6\u89c4\u5b9a\u7684\u662f\u81ea\u8eab\u5bf9\u7167\u6cd5\u3002\u8fd9\u80cc\u79bb\u4e86\u65b9\u6cd5\u9a8c\u8bc1\u7684\u672c\u610f\uff0c\u65b9\u6cd5\u9a8c\u8bc1\u5e94\u8be5\u9a8c\u8bc1\u65b9\u6cd5\u81ea\u8eab\u7684\u51c6\u786e\u5ea6\u3002\u5982\u679c\u7528\u5916\u6807\u6cd5\u56de\u6536\u7387\u5408\u683c\uff0c\u4f46\u7ebf\u6027\u9a8c\u8bc1\u51fa\u73b0\u95ee\u9898\uff0c\u6821\u6b63\u56e0\u5b50\u8ba1\u7b97\u4e0d\u51c6\u786e\uff0c\u5bfc\u81f4\u5b9e\u9645\u5de5\u4f5c\u4e2d\u68c0\u6d4b\u7ed3\u679c\u504f\u79bb\u771f\u5b9e\u503c\uff0c\u800c\u65b9\u6cd5\u9a8c\u8bc1\u5374\u5224\u65ad\u7b26\u5408\u8981\u6c42\uff0c\u8fd9\u660e\u663e\u662f\u4e0d\u5408\u7406\u7684\u3002<\/span>
<\/p>\n

 <\/span><\/p>\n

7. \u8010\u7528\u6027\uff08Robustness\uff09<\/span><\/strong><\/span>
\u5206\u6790\u65b9\u6cd5\u7684\u8010\u7528\u6027\u662f\u6307\u5728\u8bd5\u9a8c\u53c2\u6570\u88ab\u6545\u610f\u5730\u53d1\u751f\u7ec6\u5c0f\u6539\u53d8\u65f6\uff0c\u68c0\u6d4b\u4e0d\u53d7\u5f71\u54cd\u7684\u80fd\u529b\uff0c\u7528\u4e8e\u8bf4\u660e\u6b63\u5e38\u4f7f\u7528\u65f6\u7684\u53ef\u9760\u6027\u3002<\/span><\/p>\n

(1) USP\u4e2d\u5173\u4e8e\u8010\u7528\u6027\u8bd5\u9a8c\u8003\u5bdf\u7684\u6761\u4ef6\u53ca\u8303\u56f4<\/span><\/strong><\/p>\n

\u2460 \u7b49\u5ea6\u6761\u4ef6<\/span><\/p>\n

\"\u786c\u8d27\uff01\u6df1\u5ea6\u89e3\u8bfb\u5206\u6790\u65b9\u6cd5\u5b66\u9a8c\u8bc1\u5404\u9879\u5173\u952e\u6307\u6807\u8981\u6c42\"<\/p>\n

 <\/span>
<\/p>\n

\u2461 \u68af\u5ea6\u6761\u4ef6<\/span><\/p>\n

\"\u786c\u8d27\uff01\u6df1\u5ea6\u89e3\u8bfb\u5206\u6790\u65b9\u6cd5\u5b66\u9a8c\u8bc1\u5404\u9879\u5173\u952e\u6307\u6807\u8981\u6c42\"<\/p>\n

 <\/span>
<\/p>\n

(2) EP\u4e2d\u5173\u4e8e\u8010\u7528\u6027\u8bd5\u9a8c\u8003\u5bdf\u7684\u6761\u4ef6\u53ca\u8303\u56f4<\/span><\/strong><\/span><\/p>\n

\u2460 \u7b49\u5ea6\u6761\u4ef6<\/span><\/p>\n

\"\u786c\u8d27\uff01\u6df1\u5ea6\u89e3\u8bfb\u5206\u6790\u65b9\u6cd5\u5b66\u9a8c\u8bc1\u5404\u9879\u5173\u952e\u6307\u6807\u8981\u6c42\"<\/p>\n

 <\/span>
<\/p>\n

\u2461 \u68af\u5ea6\u6761\u4ef6<\/span><\/span><\/p>\n

\"\u786c\u8d27\uff01\u6df1\u5ea6\u89e3\u8bfb\u5206\u6790\u65b9\u6cd5\u5b66\u9a8c\u8bc1\u5404\u9879\u5173\u952e\u6307\u6807\u8981\u6c42\"<\/p>\n

 <\/span><\/strong>
<\/p>\n

\u90e8\u5206\u53c2\u8003\u8d44\u6599\u6765\u6e90\uff1aICH\u6307\u5bfc\u539f\u5219\u3001EP\u3001USP\u3001\u5360\u5c0f\u5175\u3002<\/span><\/strong><\/span><\/p>\n

\"\u786c\u8d27\uff01\u6df1\u5ea6\u89e3\u8bfb\u5206\u6790\u65b9\u6cd5\u5b66\u9a8c\u8bc1\u5404\u9879\u5173\u952e\u6307\u6807\u8981\u6c42\"<\/p>\n<\/p>\n

<\/span><\/span><\/strong><\/strong><\/span><\/strong><\/section>\n
\u4ee5\u4e0a\u56fe\u6587\u8f6c\u8f7d\u81ea\u836f\u54c1\u7814\u53d1\u9a7f\u7ad9\uff0c\u5982\u6d89\u53ca\u7248\u6743\u95ee\u9898\uff0c<\/span>\u8bf7\u4e0e\u5c0f\u7f16\u8054\u7cfb\u6211\u4eec\u4f1a\u59a5\u5584\u5904\u7406<\/span><\/span><\/strong><\/strong><\/span><\/strong>
<\/section>\n

\u4e2d\u7f8e\u836f\u5178\u5206\u6790\u65b9\u6cd5\u9a8c\u8bc1\u3001\u8f6c\u79fb\u4e0e\u786e\u8ba4\u7814\u8ba8\u4f1a<\/span><\/strong><\/p>\n<\/p>\n

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2020\u5e74\u7248\u4e2d\u56fd\u836f\u5178\u5173\u4e8e\u65b9\u6cd5\u5b66\u7684\u5f81\u6c42\u610f\u89c1\u7a3f\u7684\u89e3\u8bfb\u4e0e\u8ba8\u8bba<\/strong>
<\/p>\n

\n
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\u4e00\u3001\u65b9\u6cd5\u5b66\u9a8c\u8bc1\u7684\u4fee\u8ba2\u5185\u5bb9\u89e3\u8bfb\u53ca\u95ee\u9898<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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1. \u9898\u76ee\u7684\u4fee\u8ba2\uff08\u6269\u5927\u4e86\u8303\u56f4\u3001\u8f6c\u53d8\u4e86\u89c2\u5ff5\uff09<\/span><\/span><\/strong><\/p>\n

2.\u6821\u6b63\u56e0\u5b50\u90e8\u5206\u7684\u5220\u9664\uff08\u5220\u9664\u4e86\u4ec0\u4e48\uff0c\u4e3a\u4ec0\u4e48\u5220\u9664\uff09<\/span><\/span><\/strong><\/p>\n

3.\u51c6\u786e\u5ea6\u90e8\u5206\u7684\u4fee\u8ba2\uff08\u51c6\u786e\u5ea6\u53ef\u63a5\u53d7\u7684\u6807\u51c6\uff09<\/span>  <\/span><\/strong><\/p>\n

4.\u540d\u8bcd\u672f\u8bed\u7684\u4fee\u8ba2<\/span><\/span><\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u4e8c\u3001\u65b9\u6cd5\u5b66\u786e\u8ba4\u6307\u5bfc\u539f\u5219\u7684\u89e3\u8bfb<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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1. \u76ee\u7684<\/span>           <\/span><\/strong><\/p>\n

2.\u6db5\u76d6\u8303\u56f4<\/span>    <\/span><\/strong><\/p>\n

3.\u4eba\u5458\u8d44\u8d28<\/span>          <\/span><\/strong><\/p>\n

4.\u786e\u8ba4\u7684\u7ed3\u8bba\uff08\u540e\u7eed\u5e94\u6ce8\u610f\u7684\u95ee\u9898\uff09<\/span><\/span><\/strong><\/p>\n

5.\u786e\u8ba4\u539f\u5219\u3001\u8003\u5bdf\u6307\u6807\u3001\u786e\u8ba4\u8c41\u514d<\/span><\/span><\/strong><\/p>\n

6.\u5bf9\u7f8e\u56fd\u836f\u5178\u7684\u501f\u9274\uff08\u836f\u5178\u591a\u79cd\u65b9\u6cd5\u7684\u53ef\u80fd\u6027\uff09<\/span><\/span><\/strong> <\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u4e09\u3001\u65b9\u6cd5\u5b66\u8f6c\u79fb\u6307\u5bfc\u539f\u5219\u7684\u89e3\u8bfb<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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1.\u76ee\u7684<\/span>            <\/span><\/strong><\/p>\n

2.\u6db5\u76d6\u8303\u56f4<\/span>     <\/span><\/strong><\/p>\n

3.\u8f6c\u79fb\u7c7b\u578b\uff08\u5982\u4f55\u9009\u62e9\uff09<\/span><\/span><\/strong><\/p>\n

4.\u8f6c\u79fb\u7684\u5173\u952e\u70b9<\/span>    <\/span><\/strong><\/p>\n

5.\u8f6c\u79fb\u65b9\u6848\uff08\u5e94\u5305\u62ec\u7684\u5185\u5bb9\uff09<\/span><\/span><\/strong><\/p>\n

6.\u8f6c\u79fb\u65b9\u6cd5<\/span>        <\/span><\/strong><\/p>\n

7.\u8f6c\u79fb\u62a5\u544a<\/span><\/span><\/strong><\/p>\n

\u4e3b\u8bb2\u4eba\uff1a<\/span><\/strong>\u5468<\/span><\/strong>\u7acb\u6625<\/span>  <\/span><\/strong>\u5317\u4eac\u5e02\u836f\u68c0\u6240<\/span><\/strong> <\/span><\/strong>\u6240\u957f\u52a9\u7406<\/span><\/strong><\/p>\n

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\u8054<\/span> \u7cfb<\/span> \u4eba\uff1a\u6f58\u6613<\/span>      panyi2010@126.com   <\/span><\/span><\/strong><\/p>\n

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<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

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