{"id":85264,"date":"2019-04-16T00:00:50","date_gmt":"2019-04-17T03:19:28","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/85264\/"},"modified":"2019-04-17T11:19:28","modified_gmt":"2019-04-17T03:19:28","slug":"746982f348","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/85264\/","title":{"rendered":"\u901f\u9012 | \u795d\u8d3a\uff01\u9648\u5217\u5e73\u535a\u58eb\u521b\u7acb\u7684NextCure\u62df\u7eb3\u65af\u8fbe\u514b\u4e0a\u5e02"},"content":{"rendered":"
\n

\u521b\u9274\u6c47 \/ \u62a5\u9053<\/span><\/h1>\n

\u636e\u7eb3\u65af\u8fbe\u514b\u516c\u5f00\u4fe1\u606f\uff0cNextCure\u5df2\u4e8e\u8fd1\u65e5\u5411\u7f8e\u56fd\u8bc1\u5238\u4ea4\u6613\u59d4\u5458\u4f1a\u9012\u4ea4\u4e86\u7eb3\u65af\u8fbe\u514b\u4e0a\u5e02\u7533\u8bf7\uff0c\u62dfIPO\u52df\u8d448600\u4e07\u7f8e\u5143\uff0c<\/strong>\u4ea4\u6613\u4ee3\u7801\u4e3aNXTC\u3002<\/span><\/p>\n


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\"\u901f\u9012
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NextCure\u662f\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u53d1\u73b0\u5e76\u5f00\u53d1\u4e0b\u4e00\u4ee3\u514d\u75ab\u836f\u7269\u6cbb\u7597\u764c\u75c7\u548c\u5176\u4ed6\u75be\u75c5\u7684\u751f\u7269\u533b\u836f\u516c\u53f8\uff0c\u9648\u5217\u5e73\u535a\u58eb\u662f\u8be5\u516c\u53f8\u7684\u521b\u59cb\u4eba<\/strong>\u3002\u8be5\u516c\u53f8\u4e8e2016\u5e741\u6708\u548c2018\u5e7411\u6708\uff0c\u5206\u522b\u5b8c\u6210A\u8f6e6700\u4e07\u7f8e\u5143\u53ca<\/span>B\u8f6e9300\u4e07\u7f8e\u5143<\/span><\/a>\u7684\u878d\u8d44\u3002<\/span>
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NextCure\u6b63\u5728\u5f00\u53d1\u4e0b\u4e00\u4ee3\u80bf\u7624\u514d\u75ab\u7597\u6cd5\uff0c\u4ee5\u89e3\u51b3\u5bf9\u6807\u51c6\u6cbb\u7597\u6216\u73b0\u6709\u514d\u75ab\u7597\u6cd5\u65e0\u53cd\u5e94\u60a3\u8005\u7684\u533b\u7597\u9700\u6c42\u3002\u5176\u4e13\u6709\u7684FIND-IO\u2122\u6280\u672f\u81f4\u529b\u4e8e\u9274\u5b9a\u5728\u80bf\u7624\u5fae\u73af\u5883\u548c\u5176\u4ed6\u75be\u75c5\u90e8\u4f4d\u4e2d\uff0c\u65b0\u7684\u9a71\u52a8\u529f\u80fd\u6027\u514d\u75ab\u5e94\u7b54\u7684\u7ec6\u80de\u8868\u9762\u5206\u5b50\u76f8\u4e92\u4f5c\u7528\u3002NextCure\u6240\u5f00\u53d1\u7684\u65b9\u6cd5\uff0c\u7528\u4e8e\u529f\u80fd\u6027\u8bc4\u4f30\u6765\u81ea\u5065\u5eb7\u4f9b\u4f53\u548c\u60a3\u6709\u5404\u79cd\u75be\u75c5\u7684\u60a3\u8005\u7684\u539f\u4ee3\u514d\u75ab\u7ec6\u80de\u4e2d\u7684\u514d\u75ab\u901a\u8def\uff0c\u5e76\u5efa\u7acb\u6765\u81ea\u514d\u75ab\u548c\u975e\u514d\u75ab\u7ec6\u80de\u8c31\u7cfb\u7684\u7ec6\u80de\u7cfb\uff0c\u5305\u62ecT\u7ec6\u80de\u4e9a\u7fa4\u3001\u5355\u6838\u7ec6\u80de\u3001\u5de8\u566c\u7ec6\u80de\u4e9a\u7fa4\u548c\u764c\u7ec6\u80de\u7cfb\u3002<\/span><\/p>\n


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\"\u901f\u9012<\/p>\n

\u25b2<\/strong><\/span><\/strong>NextCure\u7684\u7814\u53d1\u7ba1\u7ebf\uff08\u56fe\u7247\u6765\u6e90\uff1aNextCure\u5b98\u7f51\uff09<\/span><\/strong><\/span><\/p>\n


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\u76ee\u524d\uff0cNextCure\u5df2\u7ecf\u786e\u5b9a\u4e86\u9aa8\u9ad3\u7ec6\u80de\u548cT\u7ec6\u80de\u7684\u51e0\u79cd\u9633\u6027\u548c\u9634\u6027\u514d\u75ab\u8c03\u8282\u5242\u3002\u4ece\u8fd9\u4e9b\u53d1\u73b0\u4e2d\uff0c\u8be5\u516c\u53f8\u6b63\u5728\u5f00\u53d1\u53ef\u4ee5\u5e72\u9884\u8c03\u8282\u80bf\u7624\u5fae\u73af\u5883\u5185\u514d\u75ab\u7ec6\u80de\u76f8\u4e92\u4f5c\u7528\uff0c\u4ee5\u6062\u590d\u6297\u80bf\u7624\u6d3b\u6027\u7684\u6cbb\u7597\u65b9\u6cd5\u3002\u6b64\u5916\uff0cNextCure\u6b63\u5728\u5229\u7528\u5e76\u5c06\u5176\u76ee\u524d\u7684FIND-IO\u2122\u6280\u672f\u5e94\u7528\u4e8e\u529f\u80fd\u7b5b\u9009\u65b9\u6cd5\uff0c\u4ee5\u8bc6\u522b\u6765\u81ea\u591a\u4e2a\u6cbb\u7597\u9886\u57df\u7684\u65b0\u9776\u70b9\uff0c\u5305\u62ec\u81ea\u8eab\u514d\u75ab\u548c\u795e\u7ecf\u75c5\u5b66\uff0c\u4f7f\u4e0b\u4e00\u4ee3\u514d\u75ab\u7597\u6cd5\u80fd\u591f\u8fdb\u5165\u80bf\u7624\u5b66\u4ee5\u5916\u7684\u9886\u57df\u3002<\/span><\/p>\n


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\u6b64\u5916\uff0cNextCure\u7684Siglec-15\uff08S15\uff09\u6297\u4f53NC318\u4ea7\u54c1\u5df2\u8fdb\u51651\/2\u671f\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/strong>\u8be5\u5f00\u653e\u5f0f\u6807\u7b7e\u76841\u671f\u5242\u91cf\u9012\u589e\u8bd5\u9a8c\u5c06\u8bc4\u4f30NC318\u5728\u665a\u671f\u6216\u8f6c\u79fb\u6027\u5b9e\u4f53\u7624\u60a3\u8005\u4e2d\u7684\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\uff0c\u5e76\u786e\u5b9a\u5176\u836f\u7406\u6d3b\u6027\u548c\/\u6216\u6700\u5927\u8010\u53d7\u5242\u91cf\u3002\u63a8\u8350\u76842\u671f\u8bd5\u9a8c\u5242\u91cf\u786e\u5b9a\u540e\uff0cNC318\u7684\u7597\u6548\u5c06\u5728\u9009\u5b9a\u7684\u80bf\u7624\u7c7b\u578b\u4e2d\u8fdb\u884c\u8bc4\u4f30\u3002\u76ee\u524d\uff0c\u8be5\u8bd5\u9a8c\u6b63\u5728\u7f8e\u56fd\u76845\u4e2a\u4e34\u5e8a\u8bd5\u9a8c\u57fa\u5730\u8fdb\u884c\u3002<\/span><\/p>\n


<\/p>\n

S15\u662f\u4e00\u79cd\u65b0\u578b\u7684\u514d\u75ab\u8c03\u8282\u9776\u70b9\uff0c\u8868\u8fbe\u4e8e\u80bf\u7624\u5fae\u73af\u5883\u4e2d\u7684\u4e00\u7ec4\u53d7\u9650\u5236\u7684\u9ad3\u6837\u7ec6\u80de\u548c\u67d0\u4e9b\u80bf\u7624\u7c7b\u578b\uff0c\u5305\u62ec\u80ba\u764c\u3001\u5375\u5de2\u764c\u548c\u5934\u9888\u764c\u3002S15\u7684\u514d\u75ab\u8c03\u8282\u529f\u80fd\u6700\u521d\u5728\u9648\u5217\u5e73\u535a\u58eb\u7684\u5b9e\u9a8c\u5ba4\u4e2d\u53d1\u73b0\u3002\u9648\u5217\u5e73\u535a\u58eb\u662fNextCure\u7684\u521b\u59cb\u4eba\uff0c\u8036\u9c81\u5927\u5b66\uff08Yale University\uff09\u533b\u5b66\u9662\u514d\u75ab\u751f\u7269\u5b66\u53ca\u76ae\u80a4\u75c5\u5b66\u548c\u533b\u5b66\u6559\u6388\u3002\u9648\u535a\u58eb\u5728\u514d\u75ab\u80bf\u7624\u5b66\u9886\u57df\u505a\u51fa\u4e86\u91cd\u8981\u8d21\u732e\uff0c\u4ed6\u548c\u4ed6\u7684\u56e2\u961f\u5728\u8bb8\u591a\u514d\u75ab\u76f8\u5173\u9776\u70b9\u7684\u53d1\u73b0\u65b9\u9762\u4f5c\u51fa\u7a81\u51fa\u8d21\u732e\uff0c\u5305\u62ecPD-1\/PD-L1\u901a\u8def\u3002<\/span><\/p>\n


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\u6211\u4eec\u795d\u613fNextCure\u987a\u5229\u4e0a\u5e02\uff0c\u5728\u540e\u7eed\u8d44\u672c\u7684\u4e0d\u65ad\u52a9\u529b\u4e0b\uff0cNC318\u7684\u8bd5\u9a8c\u987a\u5229\uff0c\u65e9\u65e5\u60e0\u53ca\u66f4\u591a\u7684\u764c\u75c7\u60a3\u8005\uff01<\/span><\/p>\n


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\u53c2\u8003\u8d44\u6599\uff1a<\/span><\/p>\n

[1] Cancer biotech NextCure files for an $86 million IPO Retrieved on April 15 2019 from https:\/\/www.nasdaq.com\/article\/cancer-biotech-nextcure-files-for-an-86-million-ipo-cm1128773<\/span><\/p>\n

[2] \u70b9\u8d5e\uff01\u9648\u5217\u5e73\u535a\u58eb\u56e2\u961f\u5e26\u6765\u7684\u4e0b\u4e00\u4ee3\u514d\u75ab\u7597\u6cd5\u6b63\u5f0f\u8fdb\u5165\u4e34\u5e8a\uff01 Retrieved on April 15 2019 from \u533b\u836f\u89c2\u6f9c<\/span><\/p>\n


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\u672c\u6587\u6765\u81ea\u5fae\u4fe1\u56e2\u961f\uff0c\u6b22\u8fce\u8f6c\u53d1\u5230\u670b\u53cb\u5708\uff0c\u8c22\u7edd\u8f6c\u8f7d\u5230\u5176\u4ed6\u5e73\u53f0\uff1b\u5982\u6709\u5f00\u8bbe\u767d\u540d\u5355\u9700\u6c42\uff0c\u8bf7\u5728\u6587\u7ae0\u5e95\u90e8\u7559\u8a00\uff1b\u5982\u6709\u5176\u4ed6\u5408\u4f5c\u9700\u6c42\uff0c\u8bf7\u8054\u7cfbwuxi_media@wuxiapptec.com<\/span><\/p>\n


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\u70ed\u95e8\u9605\u8bfb\uff1a<\/span><\/strong>
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\u8d85\u7ea7\u7ec6\u83cc\u7684\u514b\u661f\uff0c\u7ec6\u80de\u5185\u6eb6\u7d20\u5148\u9a71\u83b73000\u4e07\u6b27\u5143\u878d\u8d44<\/span><\/strong><\/a><\/p>\n

\u643a\u624b\u9ed8\u6c99\u4e1c\uff0c\u53c8\u4e00NASH\u809d\u75c5\u9886\u822a\u8005\u62dfIPO\u52df\u8d441\u4ebf\u7f8e\u5143<\/span><\/strong><\/a><\/p>\n

\u7ed3\u5408\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u7684\u7ec6\u83cc\u7597\u6cd5\u4eae\u76f8\uff0c\u65b0\u9510A\u8f6e\u878d\u8d445000\u4e07\u7f8e\u5143<\/span><\/strong><\/a><\/p>\n

2018\u5e74\u4e2d\u56fd\u521b\u65b0\u836f\u4f01\u4e1a\u8c01\u6700\u201c\u5438\u91d1\u201d\uff1f<\/span><\/strong><\/a>
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\u4e70\u4e70\u4e70\uff01<\/span><\/strong>2018\u5e74\u751f\u7269\u533b\u836f\u884c\u4e1a\u8d8510\u4ebf\u7f8e\u91d1\u7684\u5927\u5e76\u8d2d\u6709\u51e0\u591a\uff1f<\/span><\/strong><\/a>
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\u521a\u521a\uff01<\/span><\/strong>\u8bfa\u534e\u5ba3\u5e0321\u4ebf\u7f8e\u5143\u6536\u8d2dEndocyte\uff0c\u52a0\u901f\u5f00\u53d1\u764c\u75c7\u653e\u5c04\u6027\u7597\u6cd5<\/span><\/strong><\/a>
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\u524d\u7f57\u6c0f\u7814\u53d1\u603b\u88c1\u4efbCEO\uff0c\u8868\u89c2\u8f6c\u5f55\u7ec4\u5b66\u65b0\u9510\u6210\u7acb\uff0cA\u8f6e5400\u4e07\u7f8e\u5143<\/span><\/strong><\/a><\/p>\n

3.2\u4ebf\u7f8e\u5143\u521b\u4e1a\u57fa\u91d1\u6210\u7acb\uff0c\u4ee8\u5927\u5496\u9886\u8854\uff0c\u4e13\u6ce8\u751f\u547d\u79d1\u5b66\u9886\u57df<\/span><\/strong><\/a><\/p>\n

\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

\u521b\u9274\u6c47 \/ \u62a5\u9053 \u636e\u7eb3\u65af\u8fbe\u514b\u516c\u5f00\u4fe1\u606f\uff0cNextCure\u5df2\u4e8e\u8fd1\u65e5\u5411\u7f8e\u56fd\u8bc1\u5238\u4ea4\u6613\u59d4\u5458\u4f1a\u9012\u4ea4\u4e86\u7eb3\u65af\u8fbe\u514b\u4e0a\u5e02\u7533\u8bf7\uff0c\u62dfI […]<\/p>\n","protected":false},"author":1,"featured_media":85265,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/85264"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=85264"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/85264\/revisions"}],"predecessor-version":[{"id":85268,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/85264\/revisions\/85268"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/85265"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=85264"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=85264"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=85264"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}