{"id":86753,"date":"2019-04-21T00:00:50","date_gmt":"2019-04-23T03:44:05","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/86753\/"},"modified":"2019-04-23T11:44:07","modified_gmt":"2019-04-23T03:44:07","slug":"b9a529cfaf","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/86753\/","title":{"rendered":"\u80bf\u7624\u5feb\u62a5 | \u767d\u86cb\u767d\u7d2b\u6749\u9187\u52a9\u529b\u80c6\u7ba1\u764c\u6cbb\u7597"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.68px;white-space: normal;background-color: rgb(255, 255, 255);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><img class=\"__bg_gif\"      style=\"letter-spacing: 0.544px;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;color: rgb(62, 62, 62);font-size: 16px;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;visibility: visible !important;width: 677px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/5-1555991046.gif\" alt=\"\u80bf\u7624\u5feb\u62a5 | \u767d\u86cb\u767d\u7d2b\u6749\u9187\u52a9\u529b\u80c6\u7ba1\u764c\u6cbb\u7597\" title=\"\u80bf\u7624\u5feb\u62a5 | \u767d\u86cb\u767d\u7d2b\u6749\u9187\u52a9\u529b\u80c6\u7ba1\u764c\u6cbb\u7597\"  \/><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;white-space: normal;background-color: rgb(255, 255, 255);letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u80bf\u7624\u65f6\u95f4\u8fd1\u671f\u5feb\u62a5\uff0c\u5e26\u7ed9\u4f60\u6700\u65b0\u7684\u8d44\u8baf\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;white-space: normal;background-color: rgb(255, 255, 255);letter-spacing: 0.544px;line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<section style=\"max-width: 100%;white-space: normal;background-color: rgb(255, 255, 255);letter-spacing: 0.544px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-bottom: -1px;padding-right: 5px;padding-left: 5px;max-width: 100%;box-sizing: border-box;border-bottom: 2px solid rgb(95, 156, 239);display: inline-block;vertical-align: top;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(61, 170, 214);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u514d\u75ab\u6cbb\u7597\u96be\u653b\u5fae\u536b\u661f\u7a33\u5b9a\u7ed3\u76f4\u80a0\u764c<\/span><\/strong><\/p>\n<\/section>\n<section style=\"max-width: 100%;box-sizing: border-box;border-bottom: 1px solid rgb(160, 160, 160);width: 676.991px;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.68px;white-space: normal;background-color: rgb(255, 255, 255);line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.68px;white-space: normal;background-color: rgb(255, 255, 255);line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5fae\u536b\u661f\u7a33\u5b9a\u7684\u8f6c\u79fb\u6027\u7ed3\u76f4\u80a0\u764c\u901a\u5e38\u5bf9\u514d\u75ab\u6cbb\u7597\u65e0\u53cd\u5e94\u30024 \u6708 16 \u65e5\uff0cLancet Oncol \u516c\u5e03 IMblaze370 \u7814\u7a76\uff0c\u63a2\u7d22\u6b64\u7c7b\u60a3\u8005\u4e2d\u963f\u7279\u73e0\u5355\u6297+MEK \u6291\u5236\u5242 cobimetinib \u6216\u963f\u7279\u73e0\u5355\u6297\u5355\u836f\u5bf9\u6bd4\u745e\u6208\u975e\u5c3c\u4e09\u7ebf\u6cbb\u7597\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\u3002<br  \/><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/span><\/p>\n<p style=\"line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"line-height: 1.75em;\">IMblaze370 \u672a\u8fbe\u5230\u4e3b\u8981\u7814\u7a76\u7ec8\u70b9\uff0c\u8054\u5408\u7ec4\u548c\u963f\u7279\u73e0\u5355\u6297\u5355\u836f\u7ec4\u5e76\u672a\u4f18\u4e8e\u745e\u6208\u975e\u5c3c\u3002\u5c06\u514d\u75ab\u6cbb\u7597\u7684\u83b7\u76ca\u6269\u5927\u5230\u4f4e\u514d\u75ab\u708e\u75c7\u72b6\u6001\u80bf\u7624\u60a3\u8005\u4e2d\u4f9d\u65e7\u662f\u4e00\u4e2a\u5de8\u5927\u7684\u6311\u6218\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.68px;white-space: normal;background-color: rgb(255, 255, 255);line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<section class=\"\" style=\"margin-right: auto;margin-left: auto;padding: 1em;max-width: 100%;box-sizing: border-box;font-size: 1em;font-variant-numeric: normal;font-variant-east-asian: normal;white-space: normal;letter-spacing: 0.544px;widows: 1;height: 10em;line-height: 1.5em;overflow: auto;background: rgb(240, 240, 240);overflow-wrap: break-word !important;\">\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">IMblaze370 \u662f\u4e00\u9879\u591a\u4e2d\u5fc3 3 \u671f\u968f\u673a\u5bf9\u7167\u7814\u7a76\u3002<\/span><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">363 \u540d\u7ecf\u8fc7\u81f3\u5c11\u4e24\u7ebf\u6cbb\u7597\u7684\u8f6c\u79fb\u6027\u7ed3\u76f4\u80a0\u764c\u60a3\u8005\u968f\u673a\u63a5\u53d7\u963f\u7279\u73e0\u5355\u6297 840 mg Q2W \u8054\u5408 cobimetinib 60 mg Qd d1-21 Q28d\uff08n=183\uff09\uff0c\u963f\u7279\u73e0\u5355\u6297\u5355\u836f 1200 mg Q3W\uff08n=90\uff09\uff0c\u6216\u745e\u6208\u975e\u5c3c 160 mg Qd d1-21 Q28d\uff08n=90\uff09\u6cbb\u7597\u3002<\/span><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">\u6839\u636e RAS \u72b6\u6001\uff08\u91ce\u751f\u6216\u7a81\u53d8\uff09\u548c\u7b2c\u4e00\u6b21\u8f6c\u79fb\u7684\u8bca\u65ad\u65f6\u95f4\uff08\uff1c18\u4e2a\u6708\u6216\u226518\u4e2a\u6708\uff09\u5206\u5c42\u3002<\/span><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">MSI-high \u7684\u60a3\u8005\u5165\u7ec4\u4e0d\u8d85\u8fc7 5%\u3002<\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">\u4e2d\u4f4d\u968f\u8bbf 7.3 \u4e2a\u6708\uff0c\u4e09\u7ec4\u7684\u4e2d\u4f4d OS \u5206\u522b\u662f 8.87 \u6708 vs 7.10 \u6708 vs 8.51 \u6708\uff0c\u8054\u5408\u7ec4\u5bf9\u6bd4\u745e\u6208\u975e\u5c3c\u7684 HR 1.00\uff0c\u963f\u7279\u73e0\u5355\u6297\u5bf9\u6bd4\u745e\u6208\u975e\u5c3c\u7684 HR 1.19\u3002<\/span><\/p>\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 14px;color: rgb(178, 178, 178);\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">3-4 \u7ea7\u4e0d\u826f\u4e8b\u4ef6\u53d1\u751f\u7387 61% vs 31% vs 58%\u3002<\/span><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">\u8054\u5408\u7ec4\u6700\u5e38\u89c1\u7684 3-4 \u7ea7\u4e0d\u826f\u4e8b\u4ef6\u662f\u8179\u6cfb\uff0811%\uff09\uff0c\u8d2b\u8840\uff086%\uff09\uff0c\u808c\u9178\u78f7\u9178\u6fc0\u9176\u5347\u9ad8\uff087%\uff09\u548c\u4e4f\u529b\uff084%\uff09\u3002<\/span><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\u53d1\u751f\u7387\u662f 40% vs 17% vs 23%\u3002<\/span><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">\u8054\u5408\u7ec4\uff08\u8113\u6bd2\u8840\u75c7\uff09\u548c\u745e\u6208\u975e\u5c3c\u7ec4\uff08\u80a0\u7a7f\u5b54\uff09\u5404 1 \u4f8b\u6cbb\u7597\u76f8\u5173\u6b7b\u4ea1\u3002<\/span><span style=\"max-width: 100%;letter-spacing: 0.544px;color: rgb(178, 178, 178);font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/span><\/p>\n<p><span style=\"max-width: 100%;letter-spacing: 0.544px;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;color: rgb(178, 178, 178);font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/span><\/p>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;font-variant-numeric: normal;font-variant-east-asian: normal;white-space: normal;background-color: rgb(255, 255, 255);letter-spacing: 0.544px;widows: 1;text-align: center;line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;color: rgb(136, 136, 136);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\uff08\u6ed1\u52a8\u67e5\u770b\u7814\u7a76\u8be6\u60c5\uff09<\/span><\/p>\n<p><br  \/><\/p>\n<section style=\"max-width: 100%;white-space: normal;background-color: rgb(255, 255, 255);letter-spacing: 0.544px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-bottom: -1px;padding-right: 5px;padding-left: 5px;max-width: 100%;box-sizing: border-box;border-bottom: 2px solid rgb(95, 156, 239);display: inline-block;vertical-align: top;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(61, 170, 214);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u66f2\u59a5\u73e0\u5355\u6297\u76ae\u4e0b\u7ed9\u836f\u4e0d\u8f93\u9759\u8109<\/strong><\/span><\/p>\n<\/section>\n<section style=\"max-width: 100%;box-sizing: border-box;border-bottom: 1px solid rgb(160, 160, 160);width: 676.991px;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\">JAMA Oncol \u65e5\u524d\u516c\u5e03 HannaH \u7814\u7a76 6 \u5e74\u968f\u8bbf\u7ed3\u679c\uff0c\u8bc4\u4f30\u66f2\u59a5\u73e0\u5355\u6297\u76ae\u4e0b\u6ce8\u5c04\u7528\u4e8e\u6cbb\u7597 HER2 \u9633\u6027\u65e9\u671f\u4e73\u817a\u764c\u60a3\u8005\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\u3002<\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\">\u76ae\u4e0b\u548c\u9759\u8109\u7ed9\u836f\u7ec4 6 \u5e74\u7684 EFS \u7387\u548c OS \u7387\u76f8\u540c\uff0c\u5305\u62ec\u5fc3\u810f\u4e8b\u4ef6\u5728\u5185\u7684\u4e0d\u826f\u53cd\u5e94\u53d1\u751f\u7387\u8fd1\u4f3c\u3002\u7814\u7a76\u8bc1\u5b9e\u66f2\u59a5\u73e0\u5355\u6297\u76ae\u4e0b\u7ed9\u836f\u662f HER2 \u9633\u6027\u65e9\u671f\u4e73\u817a\u764c\u60a3\u8005\u6cbb\u7597\u7684\u53e6\u4e00\u79cd\u9009\u62e9\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.68px;white-space: normal;background-color: rgb(255, 255, 255);line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<section class=\"\" style=\"margin-right: auto;margin-left: auto;padding: 1em;max-width: 100%;box-sizing: border-box;font-size: 1em;font-variant-numeric: normal;font-variant-east-asian: normal;white-space: normal;letter-spacing: 0.544px;widows: 1;height: 10em;line-height: 1.5em;overflow: auto;background: rgb(240, 240, 240);overflow-wrap: break-word !important;\">\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">HannaH \u662f\u4e00\u9879\u524d\u77bb\u6027\u591a\u4e2d\u5fc3\u65b0\u8f85\u52a9-\u8f85\u52a9\u7684\u968f\u673a 3 \u671f\u975e\u52a3\u6548\u7814\u7a76\u3002<\/span><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">\u5165\u7ec4 596 \u540d HER2 \u9633\u6027\u65e9\u671f\u4e73\u817a\u764c\u60a3\u8005\uff0c\u63a5\u53d7 8 \u5468\u671f\u5316\u7597\uff084 \u5468\u671f\u591a\u897f\u4ed6\u8d5b+4 \u5468\u671fCEF\uff09\uff0c\u540c\u65f6\u4e88\u4ee5\u56fa\u5b9a\u5242\u91cf\u66f2\u59a5\u73e0\u5355\u6297 600 mg\u76ae\u4e0b\u6ce8\u5c04\uff08n=294\uff09\uff0c\u6216\u9759\u8109\u66f2\u59a5\u73e0\u5355\u6297 8 mg\/kg\u8d1f\u8377+6 mg\/kg \u7ef4\u6301\uff08n=297\uff09Q3W \u6cbb\u7597\uff0c\u60a3\u8005\u672f\u540e\u518d\u63a5\u53d7 10 \u5468\u671f\u66f2\u59a5\u73e0\u5355\u6297\u6cbb\u7597\uff0c\u66f2\u59a5\u73e0\u5355\u6297\u7597\u7a0b\u5171 1 \u5e74\u3002<\/span><\/p>\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 14px;color: rgb(178, 178, 178);\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">\u4e24\u7ec4\u7684 6 \u5e74 EFS \u7387\u90fd\u662f 65%\uff0cHR 0.98\uff1b<\/span><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">6 \u5e74 OS \u7387\u90fd\u662f 84%\uff0cHR 0.94\u3002<\/span><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">\u8fbe\u5230 pCR \u7684\u7684\u60a3\u8005\u5177\u6709\u66f4\u9ad8\u7684 6 \u5e74 EFS \u548c OS \u7387\u3002<\/span><\/p>\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 14px;color: rgb(178, 178, 178);\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">\u4e24\u7ec4\u7684\u4e0d\u826f\u4e8b\u4ef6\u53d1\u751f\u7387\uff0897.6% vs 94.6%\uff09\uff0c3 \u7ea7\u4ee5\u4e0a\u4e0d\u826f\u4e8b\u4ef6\u53d1\u751f\u7387\uff0853.2% vs 53.7%\uff09\uff0c\u5fc3\u810f\u4e8b\u4ef6\u53d1\u751f\u7387\uff0814.8% vs 14.1%\uff09\u548c\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\u53d1\u751f\u7387\uff0821.9% vs 15.1%\uff09\u90fd\u7c7b\u4f3c\u3002<\/span><span style=\"max-width: 100%;letter-spacing: 0.544px;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;color: rgb(178, 178, 178);font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/span><\/p>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;font-variant-numeric: normal;font-variant-east-asian: normal;white-space: normal;background-color: rgb(255, 255, 255);letter-spacing: 0.544px;widows: 1;text-align: center;line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;color: rgb(136, 136, 136);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\uff08\u6ed1\u52a8\u67e5\u770b\u7814\u7a76\u8be6\u60c5\uff09<\/span><\/p>\n<p style=\"line-height: 1.75em;\"><span style=\"max-width: 100%;font-size: 14px;color: rgb(136, 136, 136);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/span><\/p>\n<p><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<section style=\"max-width: 100%;white-space: normal;background-color: rgb(255, 255, 255);letter-spacing: 0.544px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-bottom: -1px;padding-right: 5px;padding-left: 5px;max-width: 100%;box-sizing: border-box;border-bottom: 2px solid rgb(95, 156, 239);display: inline-block;vertical-align: top;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(61, 170, 214);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u8179\u8154\u7ed9\u836f\u4e0d\u6539\u5584\u5375\u5de2\u764c\u60a3\u8005\u7ed3\u5c40<\/strong><\/span><\/p>\n<\/section>\n<section style=\"max-width: 100%;box-sizing: border-box;border-bottom: 1px solid rgb(160, 160, 160);width: 676.991px;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p><br  \/><\/p>\n<p style=\"margin-bottom: 8px;max-width: 100%;min-height: 1em;letter-spacing: 0.68px;white-space: normal;background-color: rgb(255, 255, 255);line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\">JCO \u4e8e 4 \u6708 19 \u65e5\u516c\u5e03\u4e00\u9879 NRG \u80bf\u7624\/\u5987\u79d1\u80bf\u7624\u7ec4\u7814\u7a76\uff0c\u5bf9\u6bd4\u9759\u8109\u6216\u8179\u8154\u7ed9\u4e88\u5316\u7597\u836f+\u8d1d\u4f10\u73e0\u5355\u6297\u6cbb\u7597\u8fdb\u5c55\u671f\u5375\u5de2\u764c\u7684\u7597\u6548\u548c\u5b89\u5168\u6027\u3002<\/span><span style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/span><\/p>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\">\u7814\u7a76\u5206\u4e3a\u9759\u8109\u5361\u94c2\u7ec4\uff0c\u8179\u8154\u5361\u94c2\u7ec4\u548c\u8179\u8154\u987a\u94c2\u7ec4\u3002\u548c\u9759\u8109\u5361\u94c2\u7ec4\u76f8\u6bd4\uff0c\u8179\u8154\u7ed9\u836f\u6ca1\u6709\u663e\u8457\u63d0\u9ad8 PFS\u3002\u8179\u8154\u987a\u94c2\u7ec4\u7684\u8010\u53d7\u6027\u66f4\u5dee\u3002<\/p>\n<p><br  \/><\/p>\n<section class=\"\" style=\"margin-right: auto;margin-left: auto;padding: 1em;max-width: 100%;box-sizing: border-box;font-size: 1em;font-variant-numeric: normal;font-variant-east-asian: normal;white-space: normal;letter-spacing: 0.544px;widows: 1;height: 10em;line-height: 1.5em;overflow: auto;background: rgb(240, 240, 240);overflow-wrap: break-word !important;\">\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">\u4e3a\u660e\u786e\u4e24\u79cd\u4e0d\u540c\u7684\u5316\u7597\u65b9\u6848\u8179\u8154\u7ed9\u836f\u5bf9\u521d\u6cbb\u8fdb\u5c55\u671f\u5375\u5de2\u764c\u60a3\u8005 PFS \u7684\u5f71\u54cd\uff0c\u60a3\u8005\u968f\u673a\u63a5\u53d7 6 \u5468\u671f\u7d2b\u6749\u9187 80mg\/m2 QW+\u5361\u94c2AUC 6 \u9759\u8109\uff08IV\uff09\uff08\u5361\u94c2IV\u7ec4\uff09\uff0c\u7d2b\u6749\u9187 80mg\/m2 QW IV+\u5361\u94c2 AUC6 \u8179\u8154\uff08IP\uff09Q3W\uff08\u5361\u94c2IP\u7ec4\uff09\uff0c\u6216\u7d2b\u6749\u9187 135mg\/m2 IV d1\uff0c\u987a\u94c2 75mg\/m2 IP d2+\u7d2b\u6749\u9187 60mg\/m2 d8 IP Q3W\uff08\u987a\u94c2IP\u7ec4\uff09\u6cbb\u7597\u3002<\/span><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">\u6240\u6709\u60a3\u8005\u63a5\u53d7\u8d1d\u4f10\u73e0\u5355\u6297 15mg\/kg Q3W \u6cbb\u7597\u3002<\/span><\/p>\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 14px;color: rgb(178, 178, 178);\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">\u5171\u5165\u7ec4 1560 \u540d\u60a3\u8005\uff0c\u968f\u8bbf 84.8 \u4e2a\u6708\uff0c\u4e09\u7ec4\u7684 PFS \u5206\u522b\u662f 24.9 \u6708vs 27.4 \u6708 vs 26.2 \u6708\u3002<\/span><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">\u884c\u4e9a\u7ec4\u5206\u6790\uff0c\u6b8b\u4f59\u75c5\u7076\u22641cm\u7684 II\/III \u671f\u60a3\u8005\u4e2d\uff0c\u4e2d\u4f4d PFS \u5206\u522b\u662f26.9 \u6708vs 28.7 \u6708 vs 27.8 \u6708\uff1b<\/span><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">\u6ca1\u6709\u6b8b\u4f59\u75c5\u7076\u7684 II\/III \u671f\u60a3\u8005\u4e2d\u4f4d PFS \u5206\u522b\u662f35.9 \u6708vs 38.8 \u6708 vs 35.5 \u6708\u3002<\/span><\/p>\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 14px;color: rgb(178, 178, 178);\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">\u4e09\u7ec4\u7684\u4e2d\u4f4d OS \u5206\u522b\u662f 75.5 \u6708vs 78.9 \u6708 vs 72.9 \u6708\u3002<\/span><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">\u6ca1\u6709\u6b8b\u4f59\u75c5\u7076\u7684 II\/III \u671f\u60a3\u8005 OS \u5206\u522b\u662f 98.8 \u6708vs 104.8 \u6708 vs \u672a\u8fbe\u5230\u3002<\/span><\/p>\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 14px;color: rgb(178, 178, 178);\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">\u4e09\u7ec4\u7684\u795e\u7ecf\u6bd2\u6027\u7c7b\u4f3c\uff0c\u4f46\u987a\u94c2 IP \u7ec4\u7684\u529f\u80fd\u8bc4\u4f30\u66f4\u5dee\u3002<\/span><span style=\"max-width: 100%;letter-spacing: 0.544px;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;color: rgb(178, 178, 178);font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/span><\/p>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;font-variant-numeric: normal;font-variant-east-asian: normal;white-space: normal;background-color: rgb(255, 255, 255);letter-spacing: 0.544px;widows: 1;text-align: center;line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;color: rgb(136, 136, 136);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\uff08\u6ed1\u52a8\u67e5\u770b\u7814\u7a76\u8be6\u60c5\uff09<\/span><\/p>\n<p><br  \/><\/p>\n<section style=\"max-width: 100%;white-space: normal;background-color: rgb(255, 255, 255);letter-spacing: 0.544px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-bottom: -1px;padding-right: 5px;padding-left: 5px;max-width: 100%;box-sizing: border-box;border-bottom: 2px solid rgb(95, 156, 239);display: inline-block;vertical-align: top;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(61, 170, 214);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u767d\u86cb\u767d\u7d2b\u6749\u9187\u52a9\u529b\u80c6\u7ba1\u764c\u6cbb\u7597<\/span><\/strong><\/p>\n<\/section>\n<section style=\"max-width: 100%;box-sizing: border-box;border-bottom: 1px solid rgb(160, 160, 160);width: 676.991px;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\">\u5409\u897f\u4ed6\u6ee8+\u987a\u94c2\u662f\u8fdb\u5c55\u671f\u80c6\u7ba1\u764c\u7684\u6807\u51c6\u6cbb\u7597\uff0c\u4e2d\u4f4d PFS \u548c OS \u5206\u522b\u662f 8.0 \u4e2a\u6708\u548c 11.7 \u4e2a\u6708\u30024 \u6708 18 \u65e5\uff0cJAMA Oncol \u53d1\u8868\u4e00\u9879 2 \u671f\u7814\u7a76\uff0c\u8bc4\u4f30\u65b9\u6848\u4e2d\u52a0\u5165\u767d\u86cb\u767d\u7d2b\u6749\u9187\uff08nab-PTX\uff09\u662f\u5426\u53ef\u6539\u5584 PFS\u3002<\/p>\n<p style=\"line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"line-height: 1.75em;\">\u4e09\u8054\u65b9\u6848\u7684\u4e2d\u4f4d PFS 11.8 \u4e2a\u6708\uff0c\u4e2d\u4f4d OS 19.2 \u4e2a\u6708\uff0c\u4f18\u4e8e\u5386\u53f2\u5bf9\u7167\u3002\u7814\u7a76\u7ec4\u5c06\u5728 3 \u671f\u968f\u673a\u7814\u7a76\u4e2d\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u4e09\u8054\u65b9\u6848\u7684\u7597\u6548\u3002<\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.68px;white-space: normal;background-color: rgb(255, 255, 255);line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<section class=\"\" style=\"margin-right: auto;margin-left: auto;padding: 1em;max-width: 100%;box-sizing: border-box;font-size: 1em;font-variant-numeric: normal;font-variant-east-asian: normal;white-space: normal;letter-spacing: 0.544px;widows: 1;height: 10em;line-height: 1.5em;overflow: auto;background: rgb(240, 240, 240);overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;margin-bottom: 25px;line-height: 1.5em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(178, 178, 178);font-size: 14px;letter-spacing: 0.544px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u8fd9\u662f\u4e00\u9879\u5f00\u653e\u6807\u7b7e\u7684\u5355\u81c2 2 \u671f\u7814\u7a76\u3002\u5165\u7ec4 62 \u540d\u8fdb\u5c55\u671f\u80c6\u7ba1\u764c\u60a3\u8005\uff0c\u63a5\u53d7\u5409\u897f\u4ed6\u6ee8 1000mg\/<\/span><span style=\"color: rgb(178, 178, 178);letter-spacing: 0.5px;text-align: left;font-size: 1em;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\">m<\/span><span style=\"font-size: 12px;\"><sup style=\"color: rgb(178, 178, 178);letter-spacing: 0.5px;text-align: left;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\">2<\/sup><\/span><span style=\"color: rgb(178, 178, 178);font-size: 14px;letter-spacing: 0.544px;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;\">\uff0c\u987a\u94c2 25 mg\/<\/span><span style=\"text-align: left;font-size: 1em;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;color: rgb(178, 178, 178);letter-spacing: 0.5px;background-image: initial;background-position: initial;background-size: initial;background-repeat: initial;background-attachment: initial;background-origin: initial;background-clip: initial;\">m<\/span><span style=\"text-align: left;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;color: rgb(178, 178, 178);letter-spacing: 0.5px;background-image: initial;background-position: initial;background-size: initial;background-repeat: initial;background-attachment: initial;background-origin: initial;background-clip: initial;font-size: 12px;\"><sup>2<\/sup><\/span><span style=\"letter-spacing: 0.544px;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;color: rgb(178, 178, 178);font-size: 14px;\">\uff0cnab-PTX125 mg\/<span style=\"text-align: left;widows: 1;color: rgb(178, 178, 178);letter-spacing: 0.5px;background: rgb(240, 240, 240);\">m<\/span><span style=\"text-align: left;widows: 1;color: rgb(178, 178, 178);letter-spacing: 0.5px;background: rgb(240, 240, 240);font-size: 12px;\"><sup>2<\/sup><\/span> d1,8 Q21d \u6cbb\u7597\uff0c\u56e0\u524d 32 \u540d\u60a3\u8005\u8840\u6db2\u5b66\u6bd2\u6027\u8f83\u5927\uff0c\u540e 28 \u540d\u60a3\u8005\u5242\u91cf\u5206\u522b\u8c03\u6574\u4e3a 800\uff0c25\uff0c100mg\/<span style=\"text-align: left;widows: 1;color: rgb(178, 178, 178);letter-spacing: 0.5px;background: rgb(240, 240, 240);\">m<\/span><span style=\"text-align: left;widows: 1;color: rgb(178, 178, 178);letter-spacing: 0.5px;background: rgb(240, 240, 240);font-size: 12px;\"><sup>2<\/sup><\/span>\u3002<\/span><span style=\"letter-spacing: 0.544px;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;color: rgb(178, 178, 178);font-size: 14px;\">\u9996\u8981\u7814\u7a76\u7ec8\u70b9\u662f\u7814\u7a76\u8005\u8bc4\u4f30\u7684 PFS\u3002<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;margin-bottom: 25px;line-height: 1.5em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"letter-spacing: 0.544px;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;max-width: 100%;color: rgb(178, 178, 178);font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">60 \u540d\u60a3\u8005\u63a5\u53d7\u6cbb\u7597\u3002<\/span><span style=\"letter-spacing: 0.544px;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;max-width: 100%;color: rgb(178, 178, 178);font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u4e2d\u4f4d\u968f\u8bbf 12.2 \u4e2a\u6708\uff0c\u4e2d\u4f4d PFS 11.8 \u4e2a\u6708\uff0cPR \u7387 45%\uff0cDCR84%\u3002<\/span><span style=\"letter-spacing: 0.544px;font-family: -apple-system-font, BlinkMacSystemFont, &quot;Helvetica Neue&quot;, &quot;PingFang SC&quot;, &quot;Hiragino Sans GB&quot;, &quot;Microsoft YaHei UI&quot;, &quot;Microsoft YaHei&quot;, Arial, sans-serif;max-width: 100%;color: rgb(178, 178, 178);font-size: 14px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u4e2d\u4f4d OS 19.2 \u4e2a\u6708\u3002<\/span><\/p>\n<p style=\"margin-bottom: 5px;line-height: 1.5em;\"><span style=\"max-width: 100%;color: rgb(178, 178, 178);font-size: 14px;letter-spacing: 0.544px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u5b89\u5168\u6027\u8bc4\u4f30\u7684\u60a3\u8005\u4e2d\u4f4d\u63a5\u53d7 6 \u5468\u671f\u6cbb\u7597\uff0c3 \u7ea7\u4ee5\u4e0a\u4e0d\u826f\u4e8b\u4ef6\u53d1\u751f\u7387 58%\u3002<\/span><span style=\"max-width: 100%;color: rgb(178, 178, 178);font-size: 14px;letter-spacing: 0.544px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u6700\u5e38\u89c1 3 \u7ea7\u4ee5\u4e0a\u4e0d\u826f\u4e8b\u4ef6\u662f\u4e2d\u6027\u7c92\u7ec6\u80de\u51cf\u5c11\uff0833%\uff09\u3002<\/span><span style=\"max-width: 100%;color: rgb(178, 178, 178);font-size: 14px;letter-spacing: 0.544px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u4e8b\u540e\u5206\u6790\u8868\u660e\u7597\u6548\u548c\u8d77\u59cb\u5242\u91cf\u4e0d\u663e\u8457\u76f8\u5173\uff0c\u964d\u4f4e\u5242\u91cf\u540e\u8010\u53d7\u6027\u6539\u5584\u3002<\/span><\/p>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;font-variant-numeric: normal;font-variant-east-asian: normal;white-space: normal;background-color: rgb(255, 255, 255);letter-spacing: 0.544px;widows: 1;text-align: center;line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;color: rgb(136, 136, 136);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\uff08\u6ed1\u52a8\u67e5\u770b\u7814\u7a76\u8be6\u60c5\uff09<\/span><\/p>\n<p><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<section style=\"max-width: 100%;white-space: normal;background-color: rgb(255, 255, 255);letter-spacing: 0.544px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-bottom: -1px;padding-right: 5px;padding-left: 5px;max-width: 100%;box-sizing: border-box;border-bottom: 2px solid rgb(95, 156, 239);display: inline-block;vertical-align: top;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(61, 170, 214);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u514d\u75ab\u76ae\u80a4\u6bd2\u6027\u9884\u793a\u7ed3\u5c40&nbsp;<\/strong><\/span><\/p>\n<\/section>\n<section style=\"max-width: 100%;box-sizing: border-box;border-bottom: 1px solid rgb(160, 160, 160);width: 676.991px;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p><br  \/><\/p>\n<p style=\"line-height: 1.75em;\">\u514d\u75ab\u68c0\u67e5\u70b9\u963b\u6ede\u53ef\u4ee5\u4ea7\u751f\u6297\u80bf\u7624\u53cd\u5e94\u548c\u81ea\u8eab\u514d\u75ab\u6837\u6bd2\u6027\u6548\u5e94\uff0c\u8fd8\u4e0d\u6e05\u695a\u8fd9\u79cd\u8131\u9776\u6bd2\u6027\u662f\u5426\u53ef\u4ee5\u53cd\u6620\u6297\u80bf\u7624\u514d\u75ab\u529b\u3002\u6765\u81ea\u7f8e\u56fd\u8303\u5fb7\u5821\u5927\u5b66\u533b\u5b66\u4e2d\u5fc3\u7684\u4e00\u9879\u7814\u7a76\u63a2\u7d22\u4e86\u63a5\u53d7\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u6cbb\u7597\u7684\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u4e2d\uff0c\u76ae\u80a4\u6bd2\u6027\u662f\u5426\u548c\u60a3\u8005\u7ed3\u5c40\u76f8\u5173\u3002<\/p>\n<p style=\"line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"line-height: 1.75em;\">\u5206\u6790\u8868\u660e\u53d1\u751f\u76ae\u80a4\u6bd2\u6027\u7684\u60a3\u8005\u5177\u6709\u66f4\u597d\u7684 ORR\uff0cPFS \u548c OS\uff0c\u800c\u662f\u5426\u4f7f\u7528\u6fc0\u7d20\u5bf9\u60a3\u8005\u7ed3\u5c40\u5f71\u54cd\u4e0d\u5927\u3002\u7814\u7a76\u53d1\u8868\u5728 4 \u6708 18 \u65e5\u7684 JAMA Oncol \u4e0a\u3002<\/p>\n<p><br  \/><\/p>\n<section class=\"\" style=\"margin-right: auto;margin-left: auto;padding: 1em;max-width: 100%;box-sizing: border-box;font-size: 1em;font-variant-numeric: normal;font-variant-east-asian: normal;white-space: normal;letter-spacing: 0.544px;widows: 1;height: 10em;line-height: 1.5em;overflow: auto;background: rgb(240, 240, 240);overflow-wrap: break-word !important;\">\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">\u56de\u987e\u6027\u5206\u6790 318 \u540d\u63a5\u53d7\u514d\u75ab\u6cbb\u7597\u7684\u9ed1\u8272\u7d20\u60a3\u8005\u7684\u76ae\u80a4\u6bd2\u6027\uff0c\u6fc0\u7d20\u4f7f\u7528\u548c\u7ed3\u5c40\u7684\u5173\u7cfb\u3002<\/span><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">120 \u540d\uff0838%\uff09\u53d1\u751f\u76ae\u80a4\u6bd2\u6027\u7684\u60a3\u8005\u63a5\u53d7\u4f0a\u5339\u5355\u6297-\u7eb3\u6b66\u5355\u6297\u8054\u5408\u6cbb\u7597\u7684\u66f4\u591a\u3002<\/span><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">\u5177\u6709\u76ae\u80a4\u6bd2\u6027\u7684\u60a3\u8005 ORR \u66f4\u9ad8\uff0860.0%vs 28.6%\uff0cP\uff1c0.001\uff09\uff0cPFS\u66f4\u957f\uff08797 \u5929vs 112 \u5929\uff0cP\uff1c0.001\uff09\uff0cOS \u66f4\u957f\uff081691 \u5929vs 526 \u5929\uff0cP\uff1c0.001\uff09\u3002<\/span><\/p>\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 14px;color: rgb(178, 178, 178);\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">\u6bd4\u8f83\u6fc0\u7d20\u5e94\u7528\u5bf9\u7ed3\u5c40\u7684\u5f71\u54cd\uff0c\u5206\u6790\u5c40\u90e8\u4f7f\u7528\u6fc0\u7d20\uff0c\u5168\u8eab\u4f7f\u7528\u6fc0\u7d20\u548c\u672a\u4f7f\u7528\u6fc0\u7d20\u7684\u60a3\u8005\uff0c\u53d1\u73b0 ORR\uff0861.7% vs 57.1% vs 59.3%\uff0cP=0.94\uff09\uff0cPFS\uff08797\u5929 vs 305 \u5929 vs 488 \u5929\uff0cP=0.67\uff09\u548c OS\uff08\u672a\u8fbe\u5230 vs 641 \u5929 vs 1691 \u5929\uff0cP=0.30\uff09\u7c7b\u4f3c\u3002<\/span><\/p>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;font-variant-numeric: normal;font-variant-east-asian: normal;white-space: normal;background-color: rgb(255, 255, 255);letter-spacing: 0.544px;widows: 1;text-align: center;line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;color: rgb(136, 136, 136);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\uff08\u6ed1\u52a8\u67e5\u770b\u7814\u7a76\u8be6\u60c5\uff09<\/span><\/p>\n<p><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<section style=\"max-width: 100%;white-space: normal;background-color: rgb(255, 255, 255);letter-spacing: 0.544px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;text-align: center;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-bottom: -1px;padding-right: 5px;padding-left: 5px;max-width: 100%;box-sizing: border-box;border-bottom: 2px solid rgb(95, 156, 239);display: inline-block;vertical-align: top;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(61, 170, 214);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"color: rgb(61, 170, 214);letter-spacing: 0.544px;text-align: center;white-space: normal;background-color: rgb(255, 255, 255);max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-family: \u5b8b\u4f53;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/span><\/strong><\/strong><\/strong>\u672a\u6765\u5df2\u6765\uff0c\u4eba\u5de5\u667a\u80fd\u52fe\u753b\u9776\u533a<\/span><\/strong><\/strong><\/strong><\/span><\/p>\n<\/section>\n<section style=\"max-width: 100%;box-sizing: border-box;border-bottom: 1px solid rgb(160, 160, 160);width: 676.991px;overflow-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"line-height: 1.75em;\">\u653e\u7597\u533b\u5e08\u5de5\u4f5c\u91cf\u5de8\u5927\uff0c\u5df2\u7ecf\u4e0d\u80fd\u6ee1\u8db3\u65e5\u76ca\u589e\u957f\u7684\u80bf\u7624\u6cbb\u7597\u9700\u6c42\u3002\u4e3a\u660e\u786e\u7fa4\u4f53\u521b\u65b0\u662f\u5426\u53ef\u4ee5\u63a8\u52a8\u4eba\u5de5\u667a\u80fd\uff08AI\uff09\u6a21\u62df\u653e\u7597\u4e13\u5bb6\u884c\u80bf\u7624\u5206\u5272\u9776\u533a\u52fe\u753b\uff0c\u9ebb\u7701\u7684\u4f17\u591a\u533b\u9662\u5408\u4f5c\u8fdb\u884c\u4e86\u4e3a\u671f 10 \u5468\u7684\u5728\u7ebf\u5956\u52b1\u6311\u6218\u3002<\/p>\n<p style=\"line-height: 1.75em;\"><br  \/><\/p>\n<p style=\"line-height: 1.75em;\">\u8054\u5408\u7fa4\u4f53\u521b\u65b0\u548cAI\u53ef\u4ee5\u5feb\u901f\u81ea\u52a8\u751f\u6210\u7b97\u6cd5\u51c6\u786e\u6a21\u62df\u653e\u7597\u4e13\u5bb6\u7684\u6280\u80fd\uff0cAI\u7b97\u6cd5\u53ef\u80fd\u662f\u628a\u80bf\u7624\u4e13\u5bb6\u7684\u6280\u80fd\u4f20\u9012\u7ed9\u80bf\u7624\u6cbb\u7597\u8d44\u6e90\u4e0d\u8db3\u5730\u533a\u7684\u6709\u529b\u624b\u6bb5\u3002<span style=\"font-size:21px;line-height:130%;font-family:\u5b8b\u4f53;\"><\/span><\/p>\n<p><br  \/><\/p>\n<section class=\"\" style=\"margin-right: auto;margin-left: auto;padding: 1em;max-width: 100%;box-sizing: border-box;font-size: 1em;font-variant-numeric: normal;font-variant-east-asian: normal;white-space: normal;letter-spacing: 0.544px;widows: 1;height: 10em;line-height: 1.5em;overflow: auto;background: rgb(240, 240, 240);overflow-wrap: break-word !important;\">\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">\u8fd9\u662f\u4e00\u9879\u4e00\u9879\u4e3a\u671f 10 \u5468\u7684\u5728\u7ebf\u5956\u52b1\u6311\u6218\uff0c\u7b97\u6cd5\u6a21\u62df\u653e\u7597\u79d1\u4e13\u5bb6\u7684\u80bf\u7624\u5206\u5272\u3002<\/span><\/p>\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 14px;color: rgb(178, 178, 178);\"><br  \/><\/span><\/p>\n<p style=\"line-height: 1.5em;\"><span style=\"font-size: 14px;color: rgb(178, 178, 178);\">\u6765\u81ea 62 \u4e2a\u56fd\u5bb6\u7684 564 \u540d\u7ade\u4e89\u8005\u53c2\u4e0e\uff0c34 \u540d\u63d0\u4ea4\u4e86\u7b97\u6cd5\uff0c\u6700\u597d\u7684 5 \u79cd AI \u7b97\u6cd5\u53ef\u4ee5\u590d\u5236\u653e\u7597\u4e13\u5bb6\u7684\u51c6\u786e\u6027\u3002<\/span><\/p>\n<p style=\"line-height: 1.5em;\"><span style=\"letter-spacing: 0.544px;color: rgb(178, 178, 178);font-size: 14px;max-width: 100%;font-family: \u5b8b\u4f53;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><\/span><\/p>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;font-variant-numeric: normal;font-variant-east-asian: normal;white-space: normal;background-color: rgb(255, 255, 255);letter-spacing: 0.544px;widows: 1;text-align: center;line-height: 1.75em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;font-size: 14px;color: rgb(136, 136, 136);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\uff08\u6ed1\u52a8\u67e5\u770b\u7814\u7a76\u8be6\u60c5\uff09<\/span><\/p>\n<section class=\"\" style=\"max-width: 100%;box-sizing: border-box;white-space: normal;background-color: rgb(255, 255, 255);letter-spacing: 0.544px;border-width: 0px;border-style: none;border-color: initial;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"max-width: 100%;transform: translate3d(0px, 0px, 0px);box-sizing: border-box !important;overflow-wrap: break-word !important;\">\n<section class=\"\" style=\"padding-right: 10px;padding-left: 10px;max-width: 100%;box-sizing: border-box;letter-spacing: 0.7px;line-height: 1.9;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(62, 62, 62);font-size: 16px;letter-spacing: 0.544px;font-family: \u5fae\u8f6f\u96c5\u9ed1;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(62, 62, 62);font-size: 16px;letter-spacing: 0.544px;font-family: \u5fae\u8f6f\u96c5\u9ed1;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u6b22\u8fce\u5927\u5bb6\u7559\u8a00\u5206\u4eab\u6700\u65b0\u8d44\u8baf\u548c\u60f3\u6cd5~<\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(62, 62, 62);font-size: 16px;letter-spacing: 0.544px;font-family: \u5fae\u8f6f\u96c5\u9ed1;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(62, 62, 62);font-size: 16px;letter-spacing: 0.544px;font-family: \u5fae\u8f6f\u96c5\u9ed1;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;letter-spacing: 0.7px;color: rgb(136, 136, 136);font-size: 15px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u7f16\u8f91\uff1a<\/span><span style=\"max-width: 100%;letter-spacing: 0.7px;color: rgb(136, 136, 136);font-size: 15px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">decie | \u8d23\u4efb\u7f16\u8f91\uff1a\u738b\u5f18<\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(160, 160, 160);font-size: 14px;letter-spacing: 0.7px;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;letter-spacing: 0.7px;color: rgb(136, 136, 136);font-size: 15px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u6295\u7a3f\uff1adecie@qq.com<\/span><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;font-size: 16px;letter-spacing: 0.544px;font-family: \u5fae\u8f6f\u96c5\u9ed1;color: rgb(62, 62, 62);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(136, 136, 136);font-size: 15px;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u9898\u56fe\uff1a<span style=\"max-width: 100%;letter-spacing: 0.544px;text-align: left;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u7ad9\u9177\u6d77\u6d1bplus<\/span><\/span><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(62, 62, 62);font-size: 16px;letter-spacing: 0.544px;font-family: \u5fae\u8f6f\u96c5\u9ed1;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(62, 62, 62);font-size: 16px;letter-spacing: 0.544px;font-family: \u5fae\u8f6f\u96c5\u9ed1;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><br  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;color: rgb(62, 62, 62);font-size: 16px;letter-spacing: 0.544px;font-family: \u5fae\u8f6f\u96c5\u9ed1;box-sizing: border-box !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(61, 170, 214);box-sizing: border-box !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;\">\u63a8\u8350\u9605\u8bfb\uff1a<\/strong><\/span><\/p>\n<p style=\"line-height: normal;\"><a 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[&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":86754,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/86753"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=86753"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/86753\/revisions"}],"predecessor-version":[{"id":86758,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/86753\/revisions\/86758"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/86754"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=86753"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=86753"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=86753"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}