{"id":87495,"date":"2019-04-20T00:00:50","date_gmt":"2019-04-23T03:51:47","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/87495\/"},"modified":"2019-04-23T11:51:50","modified_gmt":"2019-04-23T03:51:50","slug":"d7940a67db","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/87495\/","title":{"rendered":"\u5e7f\u751f\u5802\u836f\u4e1a\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u75c5\u5168\u7403\u521b\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u83b7\u6279"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<section class=\"_135editor\"     style=\"white-space: normal;border-width: 0px;border-style: none;border-color: initial;\">\n<section>\n<section style=\"border-top: 1px solid rgb(252, 180, 43);border-left: 1px solid rgb(252, 180, 43);width: 100px;height: 14px;border-bottom-color: rgb(252, 180, 43);border-right-color: rgb(252, 180, 43);\"><br  \/><\/section>\n<section style=\"padding: 0em 0.8em;color: rgb(63, 63, 63);font-size: 14px;letter-spacing: 1.5px;\">\n<p style=\"line-height: 1.5em;\"><span style=\"background-color: rgb(255, 255, 255);font-size: 15px;text-indent: 0em;letter-spacing: normal;\">4\u670819\u65e5\uff0c\u798f\u5efa\u5e7f\u751f\u5802\u836f\u4e1a\u80a1\u4efd\u6709\u9650\u516c\u53f8\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u75c5\u5168\u7403\u521b\u65b0\u836fGST-HG151\u4e34\u5e8a\u8bd5\u9a8c\u83b7\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u6279\u51c6\u3002<\/span><\/p>\n<\/section>\n<section style=\"text-align: right;\">\n<section style=\"border-bottom: 1px solid rgb(252, 180, 43);border-right: 1px solid rgb(252, 180, 43);width: 100px;height: 14px;display: inline-block;border-top-color: rgb(252, 180, 43);border-left-color: rgb(252, 180, 43);\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-bottom: 5px;white-space: normal;text-align: center;line-height: 1.5em;\"><img class=\"rich_pages\"       src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/3-1555991508.jpeg\" alt=\"\u5e7f\u751f\u5802\u836f\u4e1a\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u75c5\u5168\u7403\u521b\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u83b7\u6279\" title=\"\u5e7f\u751f\u5802\u836f\u4e1a\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u75c5\u5168\u7403\u521b\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u83b7\u6279\"  \/><br  \/><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 10px;white-space: normal;text-align: left;line-height: 1.5em;\"><span style=\"text-align: justify;background-color: rgb(255, 255, 255);font-size: 15px;text-indent: 0em;\">\u76ee\u524d\uff0c\u5168\u7403\u8303\u56f4\u5185\u5c1a\u6ca1\u6709\u6279\u51c6\u4efb\u4f55\u836f\u7269\u7528\u4e8e\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u75c5\uff08NAFLD\uff09\u548c\u975e\u9152\u7cbe\u6027\u8102\u80aa\u6027\u809d\u708e\uff08NASH\uff09\u7684\u6cbb\u7597\uff0c\u5e7f\u751f\u5802GST-HG151\u9879\u76ee\u7684\u6210\u529f\u5f00\u53d1\uff0c\u5c06\u6709\u671b\u586b\u8865\u5168\u7403\u6297\u809d\u7ea4\u7ef4\u5316\u9886\u57df\u7684\u7a7a\u767d\uff0c\u6210\u4e3a\u5168\u7403\u6700\u65b0\u6cbb\u7597\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u75c5\u53ca\u5b9e\u73b0\u809d\u7ea4\u7ef4\u5316\u53ef\u9006\u8f6c\u7684<\/span><strong style=\"text-align: justify;\"><span style=\"text-indent: 0em;background-color: rgb(255, 255, 255);max-width: 100%;font-size: 15px;color: rgb(249, 142, 38);box-sizing: border-box !important;word-wrap: break-word !important;\">\u5168\u7403\u91cd\u78c5\u4e00\u7ebf\u521b\u65b0\u836f<\/span><\/strong><span style=\"text-align: justify;background-color: rgb(255, 255, 255);font-size: 15px;text-indent: 0em;\">\u3002<\/span><\/p>\n<p style=\"white-space: normal;text-align: center;\"><img class=\"rich_pages\"       src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/5-1555991508.jpeg\" alt=\"\u5e7f\u751f\u5802\u836f\u4e1a\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u75c5\u5168\u7403\u521b\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u83b7\u6279\" title=\"\u5e7f\u751f\u5802\u836f\u4e1a\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u75c5\u5168\u7403\u521b\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u83b7\u6279\"  \/><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 10px;white-space: normal;text-align: left;line-height: 1.5em;\"><span style=\"background-color: rgb(255, 255, 255);font-size: 15px;text-indent: 0em;text-align: justify;\">\u76ee\u524d\uff0cN<\/span><span style=\"background-color: rgb(255, 255, 255);font-size: 15px;text-indent: 0em;text-align: justify;\">ASH\u521b\u65b0\u836f\u662f\u5168\u7403\u809d\u75c5\u9886\u57df\u7684\u7814\u53d1\u70ed\u70b9\uff0cNAFLD\u662f\u6b27\u7f8e\u7b49\u897f\u65b9\u53d1\u8fbe\u56fd\u5bb6\u809d\u529f\u80fd\u9176\u5b66\u5f02\u5e38\u548c\u6162\u6027\u809d\u75c5\u6700\u5e38\u89c1\u7684\u539f\u56e0\uff0c\u666e\u901a\u6210\u4ebaNAFLD\u60a3\u75c5\u7387\u4e3a 20%\uff5e33% \uff0c\u5176\u4e2d NASH\u548c\u809d\u786c\u5316\u5206\u522b\u5360 10%\uff5e20%\u548c 2% \uff5e3%\u3002<\/span><br  \/><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 10px;white-space: normal;line-height: 1.5em;\"><span style=\"background-color: rgb(255, 255, 255);font-size: 15px;text-indent: 0em;\">\u80a5\u80d6\u75c7\u60a3\u8005 SFL\u60a3\u75c5\u7387\u4e3a 60%\uff5e90%\u3001NASH\u4e3a 20% \uff5e25%\u3001\u809d\u786c\u5316\u4e3a 2%\uff5e8% , 2\u578b\u7cd6\u5c3f\u75c5\u548c\u9ad8\u8102\u8840\u75c7\u60a3\u8005 NAFLD \u60a3\u75c5\u7387\u5206\u522b\u4e3a 28% \uff5e55%\u548c 27% \uff5e92%\u3002<\/span><span style=\"background-color: rgb(255, 255, 255);font-size: 15px;text-indent: 0em;\">\u5176\u4e2d\uff0cNASH\u60a3\u8005 (10\uff5e15)\u5e74\u5185\u809d\u786c\u5316\u53d1\u751f\u7387\u9ad8\u8fbe 15% \uff5e25%\u3002<\/span><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 10px;text-indent: 0em;white-space: normal;line-height: 1.5em;\"><span style=\"background-color: rgb(255, 255, 255);font-size: 15px;text-indent: 0em;\">\u53ef\u4ee5\u8bf4\u4e0a\u8ff0\u75c5\u75c7\u5df2\u7ecf\u6210\u4e3a\u5168\u7403\u9762\u4e34\u7684\u91cd\u5927\u5065\u5eb7\u95ee\u9898\uff0c\u6b63\u56e0\u4e0a\u8ff0\u75c5\u75c7\u7684\u666e\u904d\u6027\uff0c\u5fb7\u610f\u5fd7\u94f6\u884c\u57282014\u5e74\u53d1\u5e03\u4e86\u4e00\u4efd\u62a5\u544a\uff0c\u6307\u51fa\u5168\u7403NASH\u6cbb\u7597\u836f\u7269\u5e02\u573a\u7684\u89c4\u6a21\u52302024\u5e74\u9884\u8ba1\u5c06\u8d85\u8fc7300\u4ebf\u7f8e\u5143\u3002EvaluatePharma\u5219\u9884\u6d4b\u5168\u7403NASH\u836f\u7269\u7684\u5e02\u573a\u89c4\u6a21\u57282025\u5e74\u53ef\u4ee5\u8fbe\u5230<\/span><strong><span style=\"text-indent: 0em;letter-spacing: 0.544px;background-color: rgb(255, 255, 255);max-width: 100%;font-size: 15px;color: rgb(249, 142, 38);box-sizing: border-box !important;word-wrap: break-word !important;\">400\u4ebf<\/span><\/strong><span style=\"background-color: rgb(255, 255, 255);font-size: 15px;text-indent: 0em;\">\u7f8e\u5143\u3002<\/span><\/p>\n<p style=\"white-space: normal;text-align: center;\"><img class=\"rich_pages\"       src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/10-1555991508.jpeg\" alt=\"\u5e7f\u751f\u5802\u836f\u4e1a\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u75c5\u5168\u7403\u521b\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u83b7\u6279\" title=\"\u5e7f\u751f\u5802\u836f\u4e1a\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u75c5\u5168\u7403\u521b\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u83b7\u6279\"  \/><\/p>\n<section class=\"_135editor\"     style=\"white-space: normal;border-width: 0px;border-style: none;border-color: initial;\">\n<section style=\"margin-top: 20px;margin-bottom: 20px;text-align: center;box-sizing: border-box;\">\n<section  style=\"padding: 10px 15px 15px;display: inline-block;width: 544.875px;vertical-align: top;border-color: rgb(252, 180, 43);border-width: 1px;border-radius: 0px;border-style: solid;box-sizing: border-box;\">\n<section style=\"margin-top: -25px;margin-bottom: 20px;text-align: right;box-sizing: border-box;transform: translate3d(16px, 0px, 0px);\">\n<section  style=\"padding-left: 10px;display: inline-block;width: 205.15px;vertical-align: top;background-color: rgb(255, 255, 255);box-sizing: border-box;\">\n<section style=\"text-align: left;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;\">\n<section style=\"width: 10px;height: 10px;background: rgb(252, 180, 43);color: rgb(255, 255, 255);\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\">\n<p style=\"text-align: justify;font-size: 14px;color: rgb(63, 63, 63);letter-spacing: 1.5px;line-height: 1.5em;\"><span style=\"text-indent: 0em;background-color: rgb(255, 255, 255);font-size: 15px;letter-spacing: normal;\">GST-HG151\u9879\u76ee\u662f\u5e7f\u751f\u5802\u548c\u6218\u7565\u5408\u4f5c\u4f19\u4f34\u4e0a\u6d77\u65b0\u836f\u5f00\u53d1\u6709\u9650\u516c\u53f8\u5386\u65f6\u4e09\u5e74\u4e13\u4e1a\u5408\u4f5c\u7814\u53d1\u7684\u91cc\u7a0b\u7891\u6210\u679c\u3002<\/span><span style=\"text-indent: 0em;background-color: rgb(255, 255, 255);max-width: 100%;font-size: 15px;color: rgb(249, 142, 38);letter-spacing: normal;box-sizing: border-box !important;word-wrap: break-word !important;\">\u5e7f\u751f\u5802\u62e5\u6709GST-HG151\u5168\u7403\u77e5\u8bc6\u4ea7\u6743\uff0c\u5e76\u5df2\u5c31\u8be5\u9879\u76ee\u7533\u8bf7\u4e86\u4e24\u4e2aPCT\u56fd\u9645\u4e13\u5229\u3002<\/span><\/p>\n<\/section>\n<section style=\"margin-top: 20px;margin-bottom: -25px;text-align: left;box-sizing: border-box;transform: translate3d(-16px, 0px, 0px);\">\n<section  style=\"padding-right: 10px;display: inline-block;width: 205.15px;vertical-align: top;background-color: rgb(255, 255, 255);box-sizing: border-box;\">\n<section style=\"text-align: right;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;box-sizing: border-box;\">\n<section style=\"width: 10px;height: 10px;background: rgb(252, 180, 43);color: rgb(255, 255, 255);\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"margin-top: 10px;margin-bottom: 10px;text-indent: 0em;white-space: normal;line-height: 25.5px;\"><span style=\"background-color: rgb(255, 255, 255);font-size: 15px;text-indent: 0em;\">\u8be5\u836f\u901a\u8fc7\u4e0e\u5bf9\u5e94\u9776\u70b9\u7684\u7279\u5f02\u6027\u7ed3\u5408\uff0c\u963b\u6b62\u9776\u70b9\u4e0b\u6e38\u7684JNK\uff08c-Jun\u6c28\u57fa\u672b\u7aef\u6fc0\u9176\uff0c\u5728\u7ec6\u80de\u5468\u671f\u3001\u751f\u6b96\u3001\u51cb\u4ea1\u548c\u7ec6\u80de\u5e94\u6fc0\u7b49\u591a\u79cd\u751f\u7406\u548c\u75c5\u7406\u8fc7\u7a0b\u4e2d\u8d77\u91cd\u8981\u4f5c\u7528\uff09\u4e0ep38 MAPK\uff08\u4e1d\u88c2\u539f\u6d3b\u5316\u86cb\u767d\u6fc0\u9176\uff0c\u5176\u5728\u5f15\u8d77\u7ec6\u80de\u589e\u6b96\u3001\u5206\u5316\u3001\u8f6c\u5316\u53ca\u51cb\u4ea1\u7b49\u751f\u7269\u5b66\u53cd\u5e94\u7684\u8fc7\u7a0b\u4e2d\u5177\u6709\u81f3\u5173\u91cd\u8981\u7684\u4f5c\u7528\uff09\u901a\u8def\u6d3b\u5316\uff0c\u4ece\u800c\u51cf\u5c11\u7ec6\u80de\u51cb\u4ea1\u4e0e\u7ea4\u7ef4\u5316\u7684\u53d1\u751f\u3002<\/span><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 10px;text-indent: 0em;white-space: normal;line-height: 1.5em;\"><span style=\"background-color: rgb(255, 255, 255);font-size: 15px;text-indent: 0em;\">\u4e34\u5e8a\u524d\u7814\u7a76\u663e\u793a\uff0c\u4e34\u5e8a\u524d\u591a\u4e2a\u7528\u4e8e\u8bc4\u4ef7NASH\u6216\u809d\u7ea4\u7ef4\u5316\u52a8\u7269\u6a21\u578b\u4e2d\uff0c151\u5747\u5c55\u793a\u4e86\u6539\u5584\u809d\u529f\u80fd\u7684\u4f5c\u7528\u548c\u7edf\u8ba1\u5b66\u610f\u4e49\u4e0a\u663e\u8457\u7684\u6297\u7ea4\u7ef4\u5316\u6548\u679c\uff0c\u5177\u6709\u9776\u6807\u9009\u62e9\u6027\u597d\u3001\u6210\u836f\u6027\u5f3a\u3001\u836f\u6548\u663e\u8457\u548c\u5b89\u5168\u6027\u9ad8\u7b49\u7279\u70b9\u3002<\/span><br  \/><\/p>\n<section class=\"_135editor\"   style=\"white-space: normal;border-width: 0px;border-style: none;border-color: initial;\">\n<p style=\"text-align: center;\"><img class=\"rich_pages\"       style=\"font-size: 15px;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/5-1555991509.jpeg\" alt=\"\u5e7f\u751f\u5802\u836f\u4e1a\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u75c5\u5168\u7403\u521b\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u83b7\u6279\" title=\"\u5e7f\u751f\u5802\u836f\u4e1a\u975e\u9152\u7cbe\u6027\u8102\u80aa\u809d\u75c5\u5168\u7403\u521b\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u83b7\u6279\"  \/><\/p>\n<p style=\"margin-top: 10px;margin-bottom: 10px;line-height: 1.5em;\"><span style=\"text-indent: 0em;background-color: rgb(255, 255, 255);font-size: 15px;\">\u5e7f\u751f\u5802\u4f5c\u4e3a\u56fd\u5185\u4e13\u6ce8\u4e8e\u809d\u75c5\u6cbb\u7597\u836f\u7269\u9886\u57df\u533b\u836f\u4e0a\u5e02\u516c\u53f8\uff0c2015\u5e74\u4ee5\u6765\u5168\u9762\u542f\u52a8\u809d\u75c5\u9886\u57df\u6700\u70ed\u70b9\u3001\u96be\u70b9\u7684\u5168\u7403\u521b\u65b0\u53d1\uff0c\u79ef\u6781\u4ece\u4eff\u5236\u836f\u5411\u521b\u65b0\u836f\u8f6c\u578b\uff0c\u52aa\u529b\u62a2\u5360\u5168\u7403\u809d\u75c5\u65b0\u9886\u57df\u7684\u65b0\u9ad8\u5cf0\u3002\u76ee\u524d\u5df2\u7acb\u9879\u7814\u53d1<\/span><strong style=\"text-indent: 0em;\"><span style=\"text-indent: 0em;background-color: rgb(255, 255, 255);max-width: 100%;font-size: 15px;color: rgb(249, 142, 38);box-sizing: border-box !important;word-wrap: break-word !important;\">5<\/span><\/strong><span style=\"text-indent: 0em;background-color: rgb(255, 255, 255);font-size: 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