{"id":8827,"date":"2018-06-10T01:00:00","date_gmt":"2018-07-27T09:34:38","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/07\/27\/%e4%b9%99%e7%83%af%e5%9f%ba%e7%8e%af%e4%b8%99%e7%83%b7%e5%8f%82%e4%b8%8e%e7%9a%84%e9%92%af%e5%82%ac%e5%8c%963-%e5%8f%96%e4%bb%a3%e5%90%b2%e5%93%9a%e5%8f%8a%e8%89%b2%e6%b0%a8%e9%85%b8%e8%a1%8d%e7%94%9f\/"},"modified":"2018-07-27T17:34:42","modified_gmt":"2018-07-27T09:34:42","slug":"%e4%b9%99%e7%83%af%e5%9f%ba%e7%8e%af%e4%b8%99%e7%83%b7%e5%8f%82%e4%b8%8e%e7%9a%84%e9%92%af%e5%82%ac%e5%8c%963-%e5%8f%96%e4%bb%a3%e5%90%b2%e5%93%9a%e5%8f%8a%e8%89%b2%e6%b0%a8%e9%85%b8%e8%a1%8d%e7%94%9f","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/8827\/","title":{"rendered":"\u4e59\u70ef\u57fa\u73af\u4e19\u70f7\u53c2\u4e0e\u7684\u94af\u50ac\u53163-\u53d6\u4ee3\u5432\u54da\u53ca\u8272\u6c28\u9178\u884d\u751f\u7269\u7684\u4e0d\u5bf9\u79f0\u70ef\u4e19\u57fa\u70f7\u57fa\u5316\u53cd\u5e94"},"content":{"rendered":"
\n

\u200d\u200d<\/span>\u200d\"\u4e59\u70ef\u57fa\u73af\u4e19\u70f7\u53c2\u4e0e\u7684\u94af\u50ac\u53163-\u53d6\u4ee3\u5432\u54da\u53ca\u8272\u6c28\u9178\u884d\u751f\u7269\u7684\u4e0d\u5bf9\u79f0\u70ef\u4e19\u57fa\u70f7\u57fa\u5316\u53cd\u5e94\"<\/a><\/span><\/a><\/p>\n


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\"\u4e59\u70ef\u57fa\u73af\u4e19\u70f7\u53c2\u4e0e\u7684\u94af\u50ac\u53163-\u53d6\u4ee3\u5432\u54da\u53ca\u8272\u6c28\u9178\u884d\u751f\u7269\u7684\u4e0d\u5bf9\u79f0\u70ef\u4e19\u57fa\u70f7\u57fa\u5316\u53cd\u5e94\"<\/p>\n

\u56fe1. \u542b\u6709\u5432\u54da\u5549\u7ed3\u6784\u7684\u751f\u7269\u6d3b\u6027\u5206\u5b50\u3002\u56fe\u7247\u6765\u6e90\uff1aJ. Am. Chem. Soc.<\/em><\/span><\/p>\n


<\/p>\n

\"\u4e59\u70ef\u57fa\u73af\u4e19\u70f7\u53c2\u4e0e\u7684\u94af\u50ac\u53163-\u53d6\u4ee3\u5432\u54da\u53ca\u8272\u6c28\u9178\u884d\u751f\u7269\u7684\u4e0d\u5bf9\u79f0\u70ef\u4e19\u57fa\u70f7\u57fa\u5316\u53cd\u5e94\"<\/p>\n

\u56fe2. 3-\u53d6\u4ee3\u5432\u54da\u7684\u4e0d\u5bf9\u79f0\u70ef\u4e19\u57fa\u70f7\u57fa\u5316\u3002\u56fe\u7247\u6765\u6e90\uff1aJ. Am. Chem. Soc.<\/em><\/span><\/p>\n


<\/p>\n

\u6700\u8fd1\uff0c\u65af\u5766\u798f\u5927\u5b66<\/strong>\u7684Barry Trost<\/strong>\u6559\u6388\u56e2\u961f\u62a5\u9053\u4e86\u4e59\u70ef\u57fa\u73af\u4e19\u70f7\uff08VCPs\uff09\u4f5c\u4e3a1,3-\u5076\u6781\u4eb2\u7535\u5b50\u524d\u4f53<\/strong>\uff0c\u5728\u94af\u50ac\u5316\u5242\u7684\u6761\u4ef6\u4e0b\u4e0e3-\u70f7\u57fa\u53d6\u4ee3\u7684\u5432\u54da\u53ca\u8272\u6c28\u9178\u884d\u751f\u7269\u53d1\u751f\u4e0d\u5bf9\u79f0\u70ef\u4e19\u57fa\u5316<\/strong>\uff08AAA\uff09\u53cd\u5e94\uff0c\u76f8\u5173\u5de5\u4f5c\u53d1\u8868\u5728<\/span>J. Am. Chem. Soc. <\/strong><\/em><\/span>\u4e0a\u3002<\/span><\/p>\n

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<\/p>\n

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<\/p>\n

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\u56fe5. \u53cd\u5e94\u6761\u4ef6\u7684\u7b5b\u9009\u3002\u56fe\u7247\u6765\u6e90\uff1aJ. Am. Chem. Soc.<\/em><\/span><\/p>\n


<\/p>\n

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<\/p>\n

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<\/p>\n

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\u56fe8. 3-\u53d6\u4ee3\u5432\u54da\u5e95\u7269\u53c2\u4e0eC3-\u70ef\u4e19\u57fa\u5316\/\u73af\u5316\u53cd\u5e94\u7684\u666e\u9002\u6027\u8003\u5bdf\u3002\u56fe\u7247\u6765\u6e90\uff1aJ. Am. Chem. Soc.<\/em><\/span><\/p>\n


<\/p>\n

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<\/p>\n

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\u56fe10. \u5305\u542bDKPs\u548cDKMs\u7ed3\u6784\u7684\u751f\u7269\u6d3b\u6027\u5206\u5b50\u3002\u56fe\u7247\u6765\u6e90\uff1a J. Am. Chem. Soc.<\/em><\/span><\/p>\n


<\/p>\n

\"\u4e59\u70ef\u57fa\u73af\u4e19\u70f7\u53c2\u4e0e\u7684\u94af\u50ac\u53163-\u53d6\u4ee3\u5432\u54da\u53ca\u8272\u6c28\u9178\u884d\u751f\u7269\u7684\u4e0d\u5bf9\u79f0\u70ef\u4e19\u57fa\u70f7\u57fa\u5316\u53cd\u5e94\"<\/p>\n

\u56fe11. \u8272\u6c28\u9178\u884d\u751f\u7269\u53c2\u4e0e\u7684Pd-AAA\u53cd\u5e94\u3002\u56fe\u7247\u6765\u6e90\uff1a J. Am. Chem. Soc.<\/em><\/span><\/p>\n


<\/p>\n

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\u56fe12. \u5305\u542bDKPs\u7ed3\u6784\u7684\u5206\u5b50\u53c2\u4e0e\u7684Pd-AAA\u53cd\u5e94\u3002\u56fe\u7247\u6765\u6e90\uff1aJ. Am. Chem. Soc.<\/em><\/span><\/p>\n


<\/p>\n

\u8be5\u53cd\u5e94\u4f53\u7cfb\u7684\u5b9e\u7528\u6027\u5728Mollenine A\u7684\u5168\u5408\u6210\u4e2d\u4f53\u73b0\u5f97\u6dcb\u6f13\u5c3d\u81f4\uff0cPd-AAA\u53cd\u5e94\u4f5c\u4e3a\u5173\u952e\u6b65\u9aa4\u7ed3\u5408\u4e00\u6b65\u70ef\u70c3\u590d\u5206\u89e3\u53cd\u5e94\uff0c\u5c31\u53ef\u4ee5\u9ad8\u6548\u5b8c\u6210Mollenine A\u7684\u5168\u5408\u6210\u3002<\/span><\/p>\n

\"\u4e59\u70ef\u57fa\u73af\u4e19\u70f7\u53c2\u4e0e\u7684\u94af\u50ac\u53163-\u53d6\u4ee3\u5432\u54da\u53ca\u8272\u6c28\u9178\u884d\u751f\u7269\u7684\u4e0d\u5bf9\u79f0\u70ef\u4e19\u57fa\u70f7\u57fa\u5316\u53cd\u5e94\"<\/p>\n

\u56fe13. Mollenine A\u7684\u5168\u5408\u6210\u3002\u56fe\u7247\u6765\u6e90\uff1a J. Am. Chem. Soc.<\/em><\/span><\/p>\n


<\/p>\n

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\u56fe14. \u884d\u751f\u5316\u5b9e\u9a8c\u3002\u56fe\u7247\u6765\u6e90\uff1a J. Am. Chem. Soc.<\/em><\/span><\/p>\n


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\u56fe15. \u53ef\u80fd\u7684\u53cd\u5e94\u673a\u7406\u3002\u56fe\u7247\u6765\u6e90\uff1a J. Am. Chem. Soc.<\/em><\/span><\/p>\n


<\/p>\n

\u603b\u7ed3<\/span><\/strong><\/span><\/p>\n


<\/span><\/strong><\/span><\/p>\n

Barry Trost\u6559\u6388\u62a5\u9053\u4e86\u9996\u4f8bVCPs\u4f5c\u4e3a1,3-\u4eb2\u7535\u5076\u6781\u5b50\u53c2\u4e0e\u7684\u94af\u50ac\u53163-\u53d6\u4ee3\u5432\u54da\u53ca\u8272\u6c28\u9178\u884d\u751f\u7269\u7684\u4e0d\u5bf9\u79f0\u70ef\u4e19\u57fa\u70f7\u57fa\u5316\uff0c\u8be5\u53cd\u5e94\u5177\u6709\u4f18\u79c0\u7684\u4ea7\u7387\u53ca\u7acb\u4f53\u9009\u62e9\u6027\uff0c\u5bf9\u591a\u79cd\u4e0d\u540c\u76843-\u53d6\u4ee3\u5432\u54da\u53ca\u8272\u6c28\u9178\u884d\u751f\u7269\u5747\u5177\u6709\u5f88\u597d\u7684\u9002\u7528\u6027\u3002\u6b64\u5916\uff0c\u8be5\u53cd\u5e94\u4e5f\u53ef\u7528\u4e8e\u514b\u91cf\u7ea7\u6269\u5927\u89c4\u6a21\u7684\u5408\u6210\u8fc7\u7a0b\u4ee5\u53ca\u590d\u6742\u5929\u7136\u4ea7\u7269\u591a\u73af\u9aa8\u67b6\u7684\u6784\u5efa\u3002<\/span><\/p>\n


<\/p>\n

\u539f\u6587\uff08\u626b\u63cf\u6216\u957f\u6309\u4e8c\u7ef4\u7801\uff0c\u8bc6\u522b\u540e\u76f4\u8fbe\u539f\u6587\u9875\u9762\uff09\uff1a<\/span><\/p>\n

\"\u4e59\u70ef\u57fa\u73af\u4e19\u70f7\u53c2\u4e0e\u7684\u94af\u50ac\u53163-\u53d6\u4ee3\u5432\u54da\u53ca\u8272\u6c28\u9178\u884d\u751f\u7269\u7684\u4e0d\u5bf9\u79f0\u70ef\u4e19\u57fa\u70f7\u57fa\u5316\u53cd\u5e94\"<\/p>\n

Palladium-Catalyzed Asymmetric Allylic Alkylation of 3-Substituted-1H<\/em>-Indoles and Tryptophan Derivatives with Vinylcyclopropanes<\/span><\/p>\n

Barry M. Trost*, Wen-Ju Bai, Christoph Hohn, Yu Bai, James J. Cregg<\/span><\/p>\n

J. Am. Chem. Soc.<\/span><\/em>, 2018<\/strong>, 140<\/em>, 6710, DOI: 10.1021\/jacs.8b03656<\/span><\/p>\n


<\/span><\/p>\n

\u5bfc\u5e08\u4ecb\u7ecd<\/span><\/p>\n

Barry Trost<\/span><\/p>\n

http:\/\/www.x-mol.com\/university\/faculty\/433<\/span><\/p>\n


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\u672c\u6587\u7248\u6743\u5c5e\u4e8eX-MOL<\/strong><\/span>\uff08x-mol.com\uff09\uff0c\u672a\u7ecf\u8bb8\u53ef\u8c22\u7edd\u8f6c\u8f7d\uff01\u6b22\u8fce\u8bfb\u8005\u670b\u53cb\u4eec\u5206\u4eab\u5230\u670b\u53cb\u5708or\u5fae\u535a\uff01<\/span><\/p>\n


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\u70b9\u51fb\u201c\u9605\u8bfb\u539f\u6587<\/span>\u201d\uff0c\u67e5\u770b \u5316\u5b66 \u2022 \u6750\u6599 <\/strong>\u9886\u57df\u6240\u6709\u6536\u5f55\u671f\u520a<\/span><\/span><\/p>\n

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\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a X\u4e00MOL\u8d44\u8baf <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

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