{"id":88786,"date":"2019-04-21T00:00:50","date_gmt":"2019-04-23T04:03:43","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/88786\/"},"modified":"2019-04-23T12:03:45","modified_gmt":"2019-04-23T04:03:45","slug":"5405d1ae2e","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/88786\/","title":{"rendered":"\u3010\u5b9e\u4f53\u7624-\u60a3\u8005\u62db\u52df\u3011\u65b0\u578bPARP\u6291\u5236\u5242\u514d\u8d39\u62db\u52df\u665a\u671f\u5b9e\u4f53\u80bf\u7624\u60a3\u8005"},"content":{"rendered":"
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\u516c\u4f17\u53f7\uff1ashiyan589<\/span><\/p>\n


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\u6297\u764c\u6307\u5357\u70b9\u51fb\u4e0b\u65b9<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u5165\u7ec4\u62a5\u540d\u65b9\u5f0f\u89c1\u6587\u672b<\/span><\/strong><\/p>\n

\u2193<\/span><\/strong>\u2193<\/span><\/strong>\u2193<\/span><\/strong>\u2193<\/span><\/strong><\/span><\/strong><\/p>\n<\/section>\n<\/section>\n


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\u8981\u70b9\u63d0\u793a<\/strong><\/section>\n<\/section>\n


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1.\u57fa\u672c\u7b26\u5408\u4ee5\u4e0b\u6761\u4ef6\u7684\u60a3\u8005\u53ef\u8003\u8651\u62e8\u6253\u4e0b\u65b9\u8054\u7cfb\u7535\u8bdd\u54a8\u8be2\u62a5\u540d\u3002<\/span><\/span><\/p>\n

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2.\u65e0\u5bf9\u7167\u7ec4\u3002<\/span><\/p>\n

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\u8bd5\u9a8c\u836f\u7269\u7b80\u4ecb<\/strong><\/p>\n<\/section>\n


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\u9002\u5e94\u75c7\uff1a<\/strong><\/span><\/p>\n

\u665a\u671f\u5b9e\u4f53\u80bf\u7624<\/span><\/p>\n

\u4f5c\u7528\u673a\u5236\uff1a<\/strong><\/span><\/p>\n

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\u7814\u53d1\u8005\uff1a<\/strong><\/span><\/p>\n

\u6c5f\u897f\u9752\u5cf0\u836f\u4e1a\u6709\u9650\u516c\u53f8<\/span><\/p>\n

\u4e0a\u6d77\u8fea\u8bfa\u533b\u836f\u79d1\u6280\u6709\u9650\u516c\u53f8<\/span><\/p>\n

\u6c5f\u897f\u9752\u5cf0\u836f\u4e1a\u6709\u9650\u516c\u53f8<\/span><\/p>\n

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\u5b9e\u9a8c\u76ee\u7684<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n


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\u7b2c\u4e00\u9636\u6bb5\u7814\u7a76\uff08\u5242\u91cf\u9012\u589e\u8bd5\u9a8c\uff09\u4e3b\u8981\u76ee\u7684\uff1a<\/span><\/p>\n

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\u8bd5\u9a8c\u8bbe\u8ba1<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n


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\u67099\u4e2a\u8bd5\u9a8c\u7ec4<\/span><\/p>\n

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\u8bd5\u9a8c\u7ec41~3<\/strong>\uff1a<\/span><\/p>\n

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\u8bd5\u9a8c\u7ec44~6<\/strong>\uff1a<\/span><\/p>\n

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\u62db\u52df\u5bf9\u8c61<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n


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\u8ba1\u5212\u62db\u52df38-66\u4eba\u3002<\/strong><\/span><\/p>\n

\u5e74\u9f8418\u5c81\u81f370\u5c81\uff0c\u4e0d\u9650\u7537\u5973\u3002<\/strong><\/span><\/p>\n

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\u5165\u9009\u6807\u51c6<\/strong><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


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1  \u81ea\u613f\u53d7\u8bd5\uff0c\u5e76\u7b7e\u7f72\u77e5\u60c5\u540c\u610f\u4e66\uff1b  <\/span>
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2  \u5e74\u9f8418-70\u5c81\uff1b  <\/span><\/p>\n

3  \u7ecf\u75c5\u7406\u5b66\u786e\u8bca\u7684\u6076\u6027\u80bf\u7624\u60a3\u8005\uff1b  <\/span><\/p>\n

4\u6807\u51c6\u6cbb\u7597\u96be\u6cbb\u6216\u65e0\u6709\u6548\u6cbb\u7597\u65b9\u6cd5\u7684\u665a\u671f\u5b9e\u4f53\u7624\u60a3\u8005\uff08\u5242\u91cf\u9012\u589e\u9636\u6bb5\uff09\/\u751f\u7269\u6807\u5fd7\u7269BRCA1\u3001BRCA2\u57fa\u56e0\u7a81<\/span>\u53d8\u6216ATM\u8868\u8fbe\u9634\u6027\u7684\u80bf\u7624\u60a3\u8005\uff08\u5242\u91cf\u6269\u5c55\u9636\u6bb5\uff09\uff1b <\/span><\/p>\n

5  ECOG\u22642\uff1b  <\/span><\/p>\n

6  \u80bf\u7624\u75c5\u7076\u53ef\u4ee5\u88ab\u6d4b\u91cf\u6216\u8bc4\u4f30\uff08\u6839\u636eRECIST1.1\u6807\u51c6\uff09\uff1b  <\/span><\/p>\n

7  \u9884\u8ba1\u751f\u5b58\u671f\u22653\u4e2a\u6708\uff1b  <\/span><\/p>\n

8  \u8db3\u591f\u7684\u9aa8\u9ad3\u3001\u809d\u3001\u80be\u529f\u80fd\uff1a\uff08\u4ee5\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u5fc3\u6b63\u5e38\u503c\u4e3a\u51c6\uff09 a\uff09\u7edd\u5bf9\u4e2d\u6027\u7c92\u7ec6\u80de\u8ba1\u6570\uff08ANC\uff09\u22651.5\u00d710^9\/L b\uff09\u8840\u5c0f\u677f\uff08PLT\uff09\u2265100\u00d710^9\/L c\uff09\u8840\u7ea2\u86cb\u767d\uff08Hb\uff09\u22659.0g\/dL d\uff09\u8840\u6e05\u603b\u80c6\u7ea2\u7d20\uff08TBIL\uff09\u22641.5\u500d\u6b63\u5e38\u503c\u4e0a\u9650\uff08ULN\uff09 e\uff09ALT\uff0cAST\u6216ALP\u22642.5\u500dULN f\uff09\u8840\u6e05\u808c\u9150\uff08Cr\uff09\u2264\u6b63\u5e38\u503c\u4e0a\u9650\uff08ULN\uff09\u3002 <\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u6392\u9664\u6807\u51c6<\/strong><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n


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1  \u5df2\u77e5\u5bf9\u7814\u7a76\u836f\u7269\u6216\u540c\u7c7b\u836f\u7269\u8fc7\u654f\u6216\u8fc7\u654f\u4f53\u8d28\u7684\u53d7\u8bd5\u8005\uff1b  <\/span>
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2  \u4e4b\u524d\u5e94\u7528\u8fc7\u5176\u4ed6PARP\u6291\u5236\u5242\u8005\uff1b  <\/span><\/p>\n

3  \u8fdb\u5165\u7814\u7a76\u524d4\u5468\u5185\uff08\u6839\u636e\u4f7f\u7528\u836f\u7269\u7684\u7279\u6027\u53ef\u80fd\u4f1a\u66f4\u957f\uff0c\u4f8b\u5982\uff0c\u4f7f\u7528\u4e9a\u785d\u8132\u3001\u4e1d\u88c2\u9709\u7d20\u97006\u5468\u4ee5\u4e0a\u65b9\u53ef\u5165\u7ec4\uff09\u63a5\u53d7\u8fc7\u6297\u80bf\u7624\u6cbb\u7597\uff0c\u5305\u62ec\u5316\u7597\u3001\u653e\u7597\u3001\u5185\u5206\u6ccc\u6cbb\u7597\u3001\u514d\u75ab\u6cbb\u7597\u3001\u4e2d\u8349\u836f\u6cbb\u7597\u6216\u4f7f\u7528\u8fc7\u5176\u5b83\u7814\u7a76\u836f\u7269\uff1b  <\/span><\/p>\n

4  \u65e2\u5f804\u5468\u5185\u8fdb\u884c\u8fc7\u5927\u578b\u624b\u672f\u4e14\u672a\u5b8c\u5168\u6062\u590d\uff1b  <\/span><\/p>\n

5  \u56e0\u65e2\u5f80\u624b\u672f\u53f2\u6216\u4e25\u91cd\u7684\u80c3\u80a0\u9053\u75be\u75c5\u5982\u541e\u54bd\u56f0\u96be\u3001\u6d3b\u52a8\u6027\u80c3\u6e83\u75a1\u3001\u6e83\u75a1\u6027\u7ed3\u80a0\u708e\u3001\u514b\u9686\u6c0f\u75c5\u3001\u80a0\u6897\u963b\u7b49\uff0c\u7814\u7a76\u8005\u8ba4\u4e3a\u53ef\u80fd\u5f71\u54cd\u7814\u7a76\u836f\u7269\u7684\u5438\u6536\u3001\u5206\u5e03\u3001\u4ee3\u8c22\u7b49\uff1b  <\/span><\/p>\n

6  \u65e2\u5f80\u6216\u76ee\u524d\u60a3\u6709\u95f4\u8d28\u6027\u80ba\u708e\u3001\u5f25\u6f2b\u6027\u80ba\u7ea4\u7ef4\u5316\u3001\u653e\u5c04\u6027\u80ba\u708e\u7b49\uff1b  <\/span><\/p>\n

7  \u60a3\u6709\u4e25\u91cd\u7684\u672a\u63a7\u5236\u75be\u75c5\uff0c\u5982\u5fc3\u8840\u7ba1\u75be\u75c5\u3001\u809d\u810f\u3001\u80be\u810f\u75be\u75c5\u548c\u7cbe\u795e\u5f02\u5e38\u7b49\uff1b  <\/span><\/p>\n

8  \u6709QT\u95f4\u671f\u5ef6\u957f\u7efc\u5408\u5f81\u5bb6\u65cf\u53f2\u6216Fridericia\u6cd5\u6821\u6b63QT\u95f4\u671f\uff08QTcF\uff09\u7537\u6027\u2267450 ms\u3001\u5973\u6027\u2267470 ms\uff1b  <\/span><\/p>\n

9  \u6709\u7531\u524d\u671f\u6cbb\u7597\u5f15\u8d77\u800c\u6301\u7eed\u5b58\u5728\u7684CTCAE\u22672\u7ea7\u7684\u6bd2\u6027\u53cd\u5e94\uff08\u8131\u53d1\u9664\u5916\uff09\uff1b  <\/span><\/p>\n

10  \u6709\u75c7\u72b6\u7684\u8111\u8f6c\u79fb\uff1b  <\/span><\/p>\n

11  \u5df2\u6000\u5b55\u6216\u54fa\u4e73\u671f\u7684\u5973\u6027\u6216\u51c6\u5907\u751f\u80b2\u7684\u5973\u6027\/\u7537\u6027\u3002\u53d7\u8bd5\u8005\u5e94\u4e3a\u624b\u672f\u7edd\u80b2\u6216\u7edd\u7ecf\uff08\u5973\u6027\uff09\uff0c\u6216\u540c\u610f\u5728\u7814\u7a76\u6cbb\u7597\u671f\u95f4\u548c\u7814\u7a76\u7ed3\u675f\u540e6\u4e2a\u6708\u5185\u91c7\u7528\u533b\u5b66\u8ba4\u53ef\u7684\u907f\u5b55\u63aa\u65bd\u8fdb\u884c\u907f\u5b55\uff1b<\/span><\/p>\n

12  HBsAg\u9633\u6027\u6216HCV-Ab\u9633\u6027\u6216HIV-Ab\u9633\u6027\uff1b<\/span><\/p>\n

13  \u6709\u6d3b\u52a8\u6027\u611f\u67d3\uff08\u7531\u7814\u7a76\u8005\u5224\u65ad\uff09\uff1b<\/span><\/p>\n

14  \u9152\u7cbe\u6216\u836f\u7269\u6ee5\u7528\u6216\u4f9d\u8d56\u53f2\uff1b  <\/span><\/p>\n

15  \u7ecf\u7814\u7a76\u8005\u5224\u65ad\u6709\u5176\u5b83\u4e0d\u9002\u4e8e\u53c2\u4e0e\u7814\u7a76\u7684\u60c5\u51b5\u3002<\/span><\/p>\n


<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n

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\u4e34\u5e8a\u8bd5\u9a8c\u62a5\u540d\u65b9\u5f0f<\/span><\/section>\n

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\u626b\u63cf\u4e0b\u65b9\u4e8c\u7ef4\u7801\uff0c\u56de\u590d\u201c\u5165\u7ec4\u201d\u5373\u53ef<\/strong><\/span><\/span><\/p>\n

\u2193<\/strong>\u2193<\/strong>\u2193<\/strong>\u2193<\/strong><\/strong><\/span><\/span><\/p>\n

\"\u3010\u5b9e\u4f53\u7624-\u60a3\u8005\u62db\u52df\u3011\u65b0\u578bPARP\u6291\u5236\u5242\u514d\u8d39\u62db\u52df\u665a\u671f\u5b9e\u4f53\u80bf\u7624\u60a3\u8005\"<\/p>\n


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\"\u3010\u5b9e\u4f53\u7624-\u60a3\u8005\u62db\u52df\u3011\u65b0\u578bPARP\u6291\u5236\u5242\u514d\u8d39\u62db\u52df\u665a\u671f\u5b9e\u4f53\u80bf\u7624\u60a3\u8005\"\u70b9\u51fb\u201c<\/span>\u9605\u8bfb\u539f\u6587<\/span>\u201d\u67e5\u770b\u8be6\u60c5<\/span><\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

\u70b9\u51fb\u9a6c\u4e0a\u5165\u7ec4\u4e34\u5e8a\u8bd5\u9a8c \u516c\u4f17\u53f7\uff1ashiyan589 \u6297\u764c\u6307\u5357\u70b9\u51fb\u4e0b\u65b9 \u2193\u2193\u2193 \u5165\u7ec4\u62a5\u540d\u65b9\u5f0f\u89c1\u6587\u672b \u2193\u2193\u2193\u2193 SC […]<\/p>\n","protected":false},"author":1,"featured_media":88787,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/88786"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=88786"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/88786\/revisions"}],"predecessor-version":[{"id":88796,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/88786\/revisions\/88796"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/88787"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=88786"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=88786"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=88786"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}