{"id":88830,"date":"2019-04-21T00:00:50","date_gmt":"2019-04-23T04:03:58","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/88830\/"},"modified":"2019-04-23T12:03:59","modified_gmt":"2019-04-23T04:03:59","slug":"9cac214de5","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/88830\/","title":{"rendered":"\u3010PDL-1\/CTAL-4\u53cc\u6297\u62db\u52df\u60a3\u8005\u3011\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u53d7\u8bd5\u8005\u4e2d\u7684\u6709\u6548\u6027\u3001\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027 II \u671f\u4e34\u5e8a\u7814\u7a76"},"content":{"rendered":"
\n

\u70b9\u51fb\"\u3010PDL-1\/CTAL-4\u53cc\u6297\u62db\u52df\u60a3\u8005\u3011\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u53d7\u8bd5\u8005\u4e2d\u7684\u6709\u6548\u6027\u3001\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027<\/span><\/strong><\/strong><\/strong><\/span><\/strong><\/strong><\/strong><\/strong><\/span>\"\u3010PDL-1\/CTAL-4\u53cc\u6297\u62db\u52df\u60a3\u8005\u3011\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u53d7\u8bd5\u8005\u4e2d\u7684\u6709\u6548\u6027\u3001\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027<\/span><\/strong><\/strong><\/strong><\/strong><\/span><\/strong>\u9a6c\u4e0a\u5165\u7ec4\u4e34\u5e8a\u8bd5\u9a8c<\/span><\/strong><\/span><\/p>\n

\u516c\u4f17\u53f7\uff1ashiyan589<\/span><\/p>\n

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\u6297\u764c\u6307\u5357\u70b9\u51fb\u4e0b\u65b9<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n

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\u2193\u2193\u2193<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n

<\/a><\/p>\n
<\/a><\/p>\n
\"\u3010PDL-1\/CTAL-4\u53cc\u6297\u62db\u52df\u60a3\u8005\u3011\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u53d7\u8bd5\u8005\u4e2d\u7684\u6709\u6548\u6027\u3001\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027<\/a><\/section>\n<\/section>\n<\/section>\n
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\"\u3010PDL-1\/CTAL-4\u53cc\u6297\u62db\u52df\u60a3\u8005\u3011\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u53d7\u8bd5\u8005\u4e2d\u7684\u6709\u6548\u6027\u3001\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027<\/a><\/section>\n<\/section>\n<\/section>\n
<\/a><\/p>\n
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\"\u3010PDL-1\/CTAL-4\u53cc\u6297\u62db\u52df\u60a3\u8005\u3011\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u53d7\u8bd5\u8005\u4e2d\u7684\u6709\u6548\u6027\u3001\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027<\/a><\/p>\n<\/section>\n

\n
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\"\u3010PDL-1\/CTAL-4\u53cc\u6297\u62db\u52df\u60a3\u8005\u3011\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u53d7\u8bd5\u8005\u4e2d\u7684\u6709\u6548\u6027\u3001\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027<\/a><\/p>\n<\/section>\n

\u5165\u7ec4\u62a5\u540d\u65b9\u5f0f\u89c1\u6587\u672b<\/span><\/strong><\/p>\n

\u2193<\/span><\/strong>\u2193<\/span><\/strong>\u2193<\/span><\/strong>\u2193<\/span><\/strong><\/span><\/strong><\/p>\n<\/section>\n<\/section>\n

1.       <\/span><\/span>\u8bd5\u9a8c\u836f\u7269\u7b80\u4ecb<\/span><\/span><\/p>\n

KN046<\/span>\u662f\u5eb7\u5b81\u6770\u745e\u7814\u53d1\u7684<\/span>\u91cd\u7ec4\u4eba\u6e90\u5316<\/span>PDL1\/CTLA-4<\/span>\u53cc\u7279\u5f02\u6027\u5355\u57df\u6297\u4f53<\/span>Fc<\/span>\u878d\u5408\u86cb\u767d\u6ce8\u5c04\u6db2<\/span>\u3002<\/span><\/span><\/p>\n

\u672c\u8bd5\u9a8c\u7684\u9002\u5e94\u75c7\u662f<\/span>\u975e\u5c0f\u7ec6\u80de\u80ba\u764c<\/span>\uff0c\u5bf9\u4e8e\u975e\u9cde\u72b6\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff0c\u65e0<\/span>EGFR<\/span>\u654f\u611f\u6027\u7a81\u53d8\u6216<\/span>ALK<\/span>\u91cd\u6392\uff1b\u5bf9\u4e8e\u9cde\u72b6\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff0c\u65e0\u5df2\u77e5<\/span>EGFR<\/span>\u654f\u611f\u6027\u7a81\u53d8\uff1b\u6709<\/span>3<\/span>\u4e2a\u961f\u5217\uff1a<\/span>1<\/span>\uff09<\/span>1<\/span>\u7ebf\u542b\u94c2\u5316\u7597\u6cbb\u7597\u5931\u8d25\uff0c\u6216\u4e0d\u8010\u53d7<\/span>1<\/span>\u7ebf\u542b\u94c2\u5316\u7597\uff0c<\/span>2<\/span>\uff09\u672a\u63a5\u53d7\u8fc7\u514d\u75ab\u68c0\u67e5\u70b9\u963b\u65ad\u5242\u6216<\/span>T<\/span>\u7ec6\u80de\u5171\u523a\u6fc0\u836f\u7269\u6cbb\u7597\u7b49\uff0c\u5305\u62ec\u4f46\u4e0d\u9650\u4e8e<\/span>PD-1<\/span>\u3001<\/span>PD-L1<\/span>\u3001<\/span>CTLA4<\/span>\u3001<\/span>LAG3<\/span>\u7b49\u514d\u75ab\u68c0\u67e5\u70b9\u963b\u65ad\u5242\u3001\u6cbb\u7597\u6027\u75ab\u82d7\u7b49\uff0c<\/span>3<\/span>\uff09<\/span>PD1\/PD-L1<\/span>\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u6cbb\u7597\u5931\u8d25\u3002<\/span><\/span><\/p>\n

 <\/span><\/p>\n

2.       <\/span><\/span>\u8bd5\u9a8c\u76ee\u7684<\/span><\/span><\/p>\n

\u8bc4\u4ef7<\/span>KN046<\/span>\u5728\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u4e2d\u7684\u6297\u80bf\u7624\u6d3b\u6027<\/span>(ORR<\/span>\u548c<\/span>DOR)<\/span><\/span><\/p>\n

 <\/span><\/p>\n

3.       <\/span><\/span>\u8bd5\u9a8c\u8bbe\u8ba1<\/span><\/span><\/p>\n

\u8bd5\u9a8c\u5206\u7c7b\uff1a<\/span>  <\/span>\u5b89\u5168\u6027\u548c\u6709\u6548\u6027<\/span><\/span><\/p>\n

\u8bd5\u9a8c\u5206\u671f\uff1a<\/span>  II<\/span>\u671f<\/span><\/span><\/p>\n

\u8bbe\u8ba1\u7c7b\u578b\uff1a<\/span>  <\/span>\u5355\u81c2\u8bd5\u9a8c<\/span><\/span><\/p>\n

\u968f\u673a\u5316\uff1a<\/span>     <\/span>\u975e\u968f\u673a\u5316<\/span><\/span><\/p>\n

\u76f2\u6cd5\uff1a<\/span>        <\/span>\u5f00\u653e<\/span><\/span><\/p>\n

\u8bd5\u9a8c\u8303\u56f4\uff1a<\/span>  <\/span>\u56fd\u5185\u8bd5\u9a8c<\/span>        <\/span><\/span><\/p>\n

\u8bd5\u9a8c\u4eba\u6570\uff1a<\/span>  149<\/span>\u4eba<\/span><\/span><\/p>\n

 <\/span><\/p>\n

4.       <\/span><\/span>\u5165\u9009\u6807\u51c6<\/span><\/span><\/p>\n

1  I01. <\/span>\u53d7\u8bd5\u8005\u80fd\u591f\u7406\u89e3\u77e5\u60c5\u540c\u610f\u4e66\uff0c\u81ea\u613f\u53c2\u4e0e\u5e76\u7b7e\u7f72\u77e5\u60c5\u540c\u610f\u4e66\uff1b<\/span><\/span><\/p>\n

2  I02. <\/span>\u53d7\u8bd5\u8005\u7b7e\u7f72\u77e5\u60c5\u540c\u610f\u4e66\u5f53\u5929\u2265<\/span>18<\/span>\u5468\u5c81\u4e14\u2264<\/span>75<\/span>\u5468\u5c81\uff0c\u7537\u5973\u4e0d\u9650\uff1b<\/span><\/span><\/p>\n

3  I03. <\/span>\u7ec4\u7ec7\u5b66\u6216\u7ec6\u80de\u5b66\u8bc1\u5b9e\u4e3a\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff1b<\/span> IV<\/span>\u671f<\/span>M1a<\/span>\u6216<\/span>M1b<\/span>\uff08<\/span>AJCC<\/span>\u7b2c<\/span>8<\/span>\u7248\uff09\uff1b\u5bf9\u4e8e\u975e\u9cde\u72b6\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff0c\u65e0<\/span>EGFR<\/span>\u654f\u611f\u6027\u7a81\u53d8\u6216<\/span>ALK<\/span>\u91cd\u6392\uff1b\u5bf9\u4e8e\u9cde\u72b6\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff0c\u65e0\u5df2\u77e5<\/span>EGFR<\/span>\u654f\u611f\u6027\u7a81\u53d8<\/span><\/span><\/p>\n

4  I03-a<\/span>\uff1a\u961f\u5217<\/span>A<\/span>\u3001<\/span>B 1<\/span>\u7ebf\u542b\u94c2\u5316\u7597\u6cbb\u7597\u5931\u8d25\uff0c\u6216\u4e0d\u8010\u53d7<\/span>1<\/span>\u7ebf\u542b\u94c2\u5316\u7597\u3002\u63a5\u53d7\u8fc7\u542b\u94c2\u8f85\u52a9\u5316\u7597\u4e14\u5728\u5316\u7597\u7ed3\u675f\u540e<\/span>6<\/span>\u4e2a\u6708\u5185\u8fdb\u5c55\u7684\u53d7\u8bd5\u8005\u89c6\u4e3a<\/span>1<\/span>\u7ebf\u542b\u94c2\u5316\u7597\u6cbb\u7597\u5931\u8d25\uff1b\u4e0d\u8010\u53d7<\/span>1<\/span>\u7ebf\u542b\u94c2\u5316\u7597\u5b9a\u4e49\u4e3a\u80be\u529f\u80fd\u4e0d\u5168\uff08\u808c\u9150\u6e05\u9664\u7387<\/span><60 mL\/min<\/span>\uff09\u548c<\/span>\/<\/span>\u6216\u5fc3\u529f\u80fd\u4e0d\u5168\uff08\u7ebd\u7ea6\u5fc3\u810f\u75c5\u534f\u4f1a<\/span>[NYHA]<\/span>\u5206\u7c7b<\/span> < II<\/span>\u7ea7\uff09\u548c<\/span>\/<\/span>\u6216\u4e0d\u613f\u63a5\u53d7\u5316\u7597\u7684\u53d7\u8bd5\u8005\uff1b<\/span><\/span><\/p>\n

5  I03-a<\/span>\uff1a\u961f\u5217<\/span>A<\/span>\u3001<\/span>B <\/span>\u672a\u63a5\u53d7\u8fc7\u514d\u75ab\u68c0\u67e5\u70b9\u963b\u65ad\u5242\u6216<\/span>T<\/span>\u7ec6\u80de\u5171\u523a\u6fc0\u836f\u7269\u6cbb\u7597\u7b49\uff0c\u5305\u62ec\u4f46\u4e0d\u9650\u4e8e<\/span>PD-1<\/span>\u3001<\/span>PD-L1<\/span>\u3001<\/span>CTLA4<\/span>\u3001<\/span>LAG3<\/span>\u7b49\u514d\u75ab\u68c0\u67e5\u70b9\u963b\u65ad\u5242\u3001\u6cbb\u7597\u6027\u75ab\u82d7\u7b49\uff1b<\/span><\/span><\/p>\n

6  I03-b<\/span>\uff1a\u961f\u5217<\/span>C 1<\/span>\u7ebf\u542b\u94c2\u5316\u7597\u6cbb\u7597\u5931\u8d25\uff0c\u6216\u4e0d\u8010\u53d7<\/span>1<\/span>\u7ebf\u542b\u94c2\u5316\u7597\u3002\u63a5\u53d7\u8fc7\u542b\u94c2\u8f85\u52a9\u5316\u7597\u4e14\u5728\u5316\u7597\u7ed3\u675f\u540e<\/span>6<\/span>\u4e2a\u6708\u5185\u8fdb\u5c55\u7684\u53d7\u8bd5\u8005\u89c6\u4e3a<\/span>1<\/span>\u7ebf\u542b\u94c2\u5316\u7597\u6cbb\u7597\u5931\u8d25\uff1b\u4e0d\u8010\u53d7<\/span>1<\/span>\u7ebf\u542b\u94c2\u5316\u7597\u5b9a\u4e49\u4e3a\u80be\u529f\u80fd\u4e0d\u5168\uff08\u808c\u9150\u6e05\u9664\u7387<\/span><60 mL\/min<\/span>\uff09\u548c<\/span>\/<\/span>\u6216\u5fc3\u529f\u80fd\u4e0d\u5168\uff08\u7ebd\u7ea6\u5fc3\u810f\u75c5\u534f\u4f1a<\/span>[NYHA]<\/span>\u5206\u7c7b<\/span> < II<\/span>\u7ea7\uff09\u548c<\/span>\/<\/span>\u6216\u4e0d\u613f\u63a5\u53d7\u5316\u7597\u7684\u53d7\u8bd5\u8005\uff1b<\/span><\/span><\/p>\n

7  I03-b<\/span>\uff1a\u961f\u5217<\/span>C PD1\/PD-L1<\/span>\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u6cbb\u7597\u5931\u8d25\uff0c\u4f46\u9700\u6392\u9664<\/span>PD1\/PD-L1<\/span>\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u5f00\u59cb\u6cbb\u7597\u540e<\/span>6<\/span>\u5468\u5185\u53d1\u751f\u75be\u75c5\u8fdb\u5c55\u7684\u53d7\u8bd5\u8005\uff1b<\/span><\/span><\/p>\n

8  I03-b<\/span>\uff1a\u961f\u5217<\/span>C <\/span>\u65e2\u5f80<\/span>PD1\/PD-L1<\/span>\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u6cbb\u7597\u8fc7\u7a0b\u4e2d\u6216\u505c\u836f\u540e\u672a\u51fa\u73b0\u4e0e<\/span>PD1\/PD-L1<\/span>\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u76f8\u5173\u7684\u2265<\/span>3<\/span>\u7ea7\u514d\u75ab\u76f8\u5173\u7684\u4e0d\u826f\u53cd\u5e94\uff08\u9664\u5916\u66ff\u4ee3\u6cbb\u7597\u80fd\u63a7\u5236\u7684<\/span>3<\/span>\u7ea7\u514d\u75ab\u76f8\u5173\u5185\u5206\u6ccc\u4e0d\u826f\u4e8b\u4ef6\u548c<\/span>3<\/span>\u7ea7\u514d\u75ab\u76f8\u5173\u76ae\u80a4\u6bd2\u6027\uff09\u3001\u2265<\/span>2<\/span>\u7ea7\u514d\u75ab\u76f8\u5173\u80ba\u708e\u3001\u2265<\/span>2<\/span>\u7ea7\u514d\u75ab\u76f8\u5173\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u6bd2\u6027\u3001\u2265<\/span>1<\/span>\u7ea7\u514d\u75ab\u76f8\u5173\u5fc3\u808c\u708e\uff1b<\/span><\/span><\/p>\n

9  I03-b<\/span>\uff1a\u961f\u5217<\/span>C <\/span>\u672a\u63a5\u53d7\u8fc7\u5176\u4ed6\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u6216<\/span>T<\/span>\u7ec6\u80de\u5171\u523a\u6fc0\u836f\u7269\u6cbb\u7597\u7b49\uff0c\u5305\u62ec\u4f46\u4e0d\u9650\u4e8e<\/span>CTLA4<\/span>\u3001<\/span>LAG-3<\/span>\u7b49\u514d\u75ab\u68c0\u67e5\u70b9\u963b\u65ad\u5242\u3001\u6cbb\u7597\u6027\u75ab\u82d7\u7b49\uff1b<\/span><\/span><\/p>\n

10  I04. <\/span>\u6839\u636e<\/span>RECIST 1.1<\/span>\u6807\u51c6\uff0c\u57fa\u7ebf\u6709\u53ef\u6d4b\u91cf\u75c5\u7076\uff1b\u5982\u679c\u53d7\u8bd5\u8005\u57fa\u7ebf\u4ec5\u5b58\u5728<\/span>1<\/span>\u4e2a\u53ef\u6d4b\u91cf\u75c5\u7076\uff0c\u5219\u8be5\u75c5\u7076\u533a\u57df\u65e2\u5f80\u5fc5\u987b\u6ca1\u6709\u63a5\u53d7\u8fc7\u653e\u7597\uff0c\u6216\u8005\u6709\u8bc1\u636e\u8868\u660e\u8be5\u75c5\u7076\u5728\u653e\u7597\u6cbb\u7597\u7ed3\u675f\u540e\u660e\u663e\u8fdb\u5c55\uff1b<\/span><\/span><\/p>\n

11  I05. <\/span>\u8fd1\u671f\u83b7\u5f97\u7684\uff08\u6765\u81ea<\/span>1<\/span>\u5e74\u5185\u975e\u653e\u5c04\u533a\u57df\u7684\u6d3b\u68c0\u6807\u672c\uff09\u3001\u9002\u5408\u751f\u7269\u6807\u5fd7\u7269\u6d4b\u5b9a\u7684\u542b\u80bf\u7624\u7ec4\u7ec7\u7684\u798f\u5c14\u9a6c\u6797\u56fa\u5b9a\u3001\u77f3\u8721\u5305\u57cb\u7ec4\u7ec7\u5757\uff0c\u6216<\/span>15-20<\/span>\u5f20\u5207\u7247\uff08<\/span>1<\/span>\u5468\u5185\u5236\u5907\uff0c\u9f13\u52b1\u63d0\u4f9b\u5c3d\u53ef\u80fd\u591a\u7684\u5207\u7247\uff0c\u81f3\u5c11<\/span>8<\/span>\u5f20\uff1b\u5982\u5c11\u4e8e<\/span>8<\/span>\u5f20\u7247\u5b50\u65f6\uff0c\u7ecf\u7533\u529e\u65b9\u548c\u7814\u7a76\u8005\u5546\u91cf\u540c\u610f\u540e\u4e5f\u53ef\u5165\u7ec4\uff09\uff08\u7ae0\u8282<\/span>7.2.7<\/span>\uff09\uff1b\u961f\u5217<\/span>C<\/span>\u9700\u63d0\u4f9b\u9996\u6b21\u7ed9\u836f\u524d<\/span>42<\/span>\u5929\u5185\u91c7\u96c6\u7684\u65b0\u9c9c\u7a7f\u523a\u6d3b\u68c0\u6837\u672c\u7528\u4e8e\u6d4b\u5b9a\uff1b<\/span><\/span><\/p>\n

12  I06. ECOG<\/span>\u8bc4\u5206<\/span> 0<\/span>\u6216<\/span>1<\/span>\u5206\uff1b<\/span><\/span><\/p>\n

13  I07. <\/span>\u9996\u6b21\u7ed9\u836f\u524d<\/span>7<\/span>\u5929\u5185\u809d\u529f\u80fd\u6ee1\u8db3\u4ee5\u4e0b\u6807\u51c6\uff1a\uff1f\u603b\u80c6\u7ea2\u7d20\u2264<\/span>1 x ULN<\/span>\uff08<\/span>Gilbert<\/span>\u2019<\/span>s<\/span>\u7efc\u5408\u5f81\u3001\u809d\u764c\u6216\u809d\u8f6c\u79fb\u53d7\u8bd5\u8005\u603b\u80c6\u7ea2\u7d20\u2264<\/span>1.5 x ULN<\/span>\uff09\uff1b\uff1f\u8f6c\u6c28\u9176\uff08<\/span>ALT\/AST<\/span>\uff09\u2264<\/span>1.5 x ULN<\/span>\uff08\u809d\u764c\u6216\u809d\u8f6c\u79fb\u53d7\u8bd5\u8005\u2264<\/span>2.5 x ULN<\/span>\uff09\uff1b\u5bf9\u4e8e\u809d\u8f6c\u79fb\u53d7\u8bd5\u8005\uff0c\u987b\u6392\u9664\u8f6c\u6c28\u9176\u2265<\/span>3 x ULN<\/span>\u4e14\u603b\u80c6\u7ea2\u7d20\u2265<\/span>1.5 x ULN<\/span>\u7684\u60c5\u51b5\uff1b<\/span><\/span><\/p>\n

14  I09. <\/span>\u9996\u6b21\u7ed9\u836f\u524d<\/span>7<\/span>\u5929\u5185\u9aa8\u9ad3\u529f\u80fd\u6ee1\u8db3\u4ee5\u4e0b\u6807\u51c6\uff1a\u8840\u7ea2\u7d20\u2265<\/span>9.0 g\/dL<\/span>\uff1b\u4e2d\u6027\u7c92\u7ec6\u80de\u7edd\u5bf9\u8ba1\u6570\u2265<\/span>1.5 x 109\/L<\/span>\uff1b\u8840\u5c0f\u677f\u8ba1\u6570\u2265<\/span>100 x 109\/L<\/span>\uff1b<\/span><\/span><\/p>\n

15  I10. <\/span>\u5177\u6709\u751f\u80b2\u80fd\u529b\u7684\u5973\u6027\u53d7\u8bd5\u8005\u6216\u4f34\u4fa3\u6709\u751f\u80b2\u80fd\u529b\u7684\u7537\u6027\u53d7\u8bd5\u8005\u540c\u610f\u4ece\u9996\u6b21\u7ed9\u836f\u524d<\/span>7<\/span>\u5929\u5f00\u59cb\u91c7\u7528\u9ad8\u6548\u907f\u5b55\u63aa\u65bd\uff08\u5e74\u5931\u8d25\u7387\u4f4e\u4e8e<\/span>1%<\/span>\uff09\u76f4\u81f3\u7ed9\u836f\u540e<\/span>24<\/span>\u5468\uff08\u89c1\u9644\u5f55<\/span>4<\/span>\uff09\u3002\u5177\u6709\u751f\u80b2\u80fd\u529b\u7684\u5973\u6027\u53d7\u8bd5\u8005\u5728\u9996\u6b21\u7ed9\u836f\u524d<\/span>7<\/span>\u5929\u5185\u8840\u6e05\u598a\u5a20\u8bd5\u9a8c\u5fc5\u987b\u4e3a\u9634\u6027\uff1b<\/span><\/span><\/p>\n

16  I11. <\/span>\u53d7\u8bd5\u8005\u6709\u80fd\u529b\u5e76\u613f\u610f\u9075\u5b88\u7814\u7a76\u65b9\u6848\u89c4\u5b9a\u7684\u8bbf\u89c6\u3001\u6cbb\u7597\u8ba1\u5212\u3001\u5b9e\u9a8c\u5ba4\u68c0\u67e5\u548c\u5176\u4ed6\u7814\u7a76\u76f8\u5173\u6d41\u7a0b\u3002<\/span><\/span><\/p>\n

 <\/span><\/p>\n

5.       <\/span><\/span>\u6392\u9664\u6807\u51c6<\/span><\/span><\/p>\n

1  E01. <\/span>\u672a\u7ecf\u6cbb\u7597\u7684\u6d3b\u52a8\u6027\u8111\u8f6c\u79fb\u53d7\u8bd5\u8005\uff1b\u5982\u679c\u53d7\u8bd5\u8005\u7684\u8111\u8f6c\u79fb\u7076\u7ecf\u8fc7\u6cbb\u7597\uff0c\u4e14\u8f6c\u79fb\u7076\u75c5\u60c5\u7a33\u5b9a\uff08\u9996\u6b21\u7ed9\u836f\u524d\u81f3\u5c11<\/span>2<\/span>\u6b21\u95f4\u9694<\/span>4<\/span>\u5468\u7684\u8111\u90e8\u5f71\u50cf\u5b66\u68c0\u67e5\u663e\u793a\u75c5\u7076\u7a33\u5b9a\uff0c\u4e14\u6ca1\u6709\u65b0\u53d1\u795e\u7ecf\u7cfb\u7edf\u75c7\u72b6\uff0c\u6216\u795e\u7ecf\u7cfb\u7edf\u75c7\u72b6\u5df2\u6062\u590d\u81f3\u57fa\u7ebf\u6c34\u5e73\uff09\u3001\u6ca1\u6709\u65b0\u53d1\u6216\u539f\u5148\u8111\u8f6c\u79fb\u7076\u589e\u5927\u7684\u8bc1\u636e\uff0c\u5219\u5141\u8bb8\u5165\u7ec4\uff1b\u624b\u672f\u548c<\/span>\/<\/span>\u6216\u653e\u7597\u672a\u5145\u5206\u6cbb\u7597\u7684\u810a\u9ad3\u53d7\u538b\uff0c\u6216\u65e2\u5f80\u8bca\u65ad\u548c\u6cbb\u7597\u7684\u810a\u9ad3\u53d7\u538b\u5728\u9996\u6b21\u7ed9\u836f\u524d\u81f3\u5c11<\/span>1<\/span>\u5468\u524d\u65e0\u8bc1\u636e\u8868\u660e\u75be\u75c5\u4e34\u5e8a\u7a33\u5b9a\uff1b\u8f6f\u8111\u819c\u8f6c\u79fb\u3002<\/span><\/span><\/p>\n

2  E02. <\/span>\u672c\u8bd5\u9a8c\u7ed9\u836f\u524d<\/span>28<\/span>\u5929\u5185\u53c2\u52a0\u8fc7\u4efb\u4f55\u5176\u4ed6\u4e34\u5e8a\u8bd5\u9a8c\uff1b<\/span><\/span><\/p>\n

3  E03. <\/span>\u672c\u8bd5\u9a8c\u7ed9\u836f\u524d<\/span>28<\/span>\u5929\u5185\u63a5\u53d7\u8fc7\u5176\u4ed6\u6297\u80bf\u7624\u6cbb\u7597\uff0c\u5305\u62ec\u6709\u6297\u80bf\u7624\u9002\u5e94\u75c7\u7684\u4e2d\u836f\uff1b<\/span><\/span><\/p>\n

4  E04. <\/span>\u672c\u8bd5\u9a8c\u7ed9\u836f\u524d<\/span>28<\/span>\u5185\u63a5\u53d7\u8fc7\u91cd\u5927\u624b\u672f\u6cbb\u7597\uff08\u5982\u7ecf\u8179\u3001\u7ecf\u80f8\u7b49\u91cd\u5927\u624b\u672f\uff1b\u4e0d\u5305\u62ec\u8bca\u65ad\u6027\u7a7f\u523a\u6216\u5916\u5468\u8840\u7ba1\u901a\u8def\u7f6e\u6362\u672f\uff09\uff1b<\/span><\/span><\/p>\n

5  E05. <\/span>\u672c\u8bd5\u9a8c\u7ed9\u836f\u524d<\/span>3<\/span>\u4e2a\u6708\u5185\u63a5\u53d7\u8fc7\u6839\u6cbb\u6027\u653e\u7597\uff1b\u5141\u8bb8\u7ed9\u836f\u524d<\/span>2<\/span>\u5468\u63a5\u53d7\u59d1\u606f\u6027\u653e\u7597\u3001\u653e\u7597\u5242\u91cf\u7b26\u5408\u5f53\u5730\u59d1\u606f\u6027\u6cbb\u7597\u7684\u8bca\u7597\u6807\u51c6\u4e14\u653e\u7597\u8986\u76d6\u8303\u56f4\u5c0f\u4e8e<\/span>30%<\/span>\u9aa8\u9ad3\u533a\u57df\uff1b<\/span><\/span><\/p>\n

6  E06. <\/span>\u672c\u7814\u7a76\u7ed9\u836f\u524d<\/span>14<\/span>\u5929\u5185\u9700\u8981\u63a5\u53d7\u7cfb\u7edf\u6027\u76ae\u8d28\u6fc0\u7d20\uff08<\/span>>10 mg\/<\/span>\u5929\u5f3a\u7684\u677e\uff0c\u6216\u7b49\u5f53\u91cf\u7684\u5176\u4ed6\u76ae\u8d28\u6fc0\u7d20\uff09\u6216\u514d\u75ab\u6291\u5236\u5242\u6cbb\u7597\uff1b\u9664\u5916\u5438\u5165\u6216\u5c40\u90e8\u5e94\u7528\u6fc0\u7d20\uff0c\u6216\u56e0\u80be\u4e0a\u817a\u529f\u80fd\u4e0d\u5168\u800c\u63a5\u53d7\u751f\u7406\u66ff\u4ee3\u5242\u91cf\u7684\u6fc0\u7d20\u6cbb\u7597\uff1b<\/span><\/span><\/p>\n

7  E07. <\/span>\u672c\u7814\u7a76\u7ed9\u836f\u524d<\/span>28<\/span>\u5929\u5185\u63a5\u53d7\u8fc7\u6d3b\u75ab\u82d7\uff08\u5305\u62ec\u51cf\u6bd2\u6d3b\u75ab\u82d7\uff09\u63a5\u79cd\uff1b<\/span><\/span><\/p>\n

8  E08. <\/span>\u65e2\u5f80\u6216\u76ee\u524d\u60a3\u6709\u95f4\u8d28\u6027\u80ba\u708e<\/span>\/<\/span>\u80ba\u75c5\uff1b<\/span><\/span><\/p>\n

9  E09. <\/span>\u65e2\u5f80\u6216\u76ee\u524d\u60a3\u6709\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\uff0c\u5305\u62ec\u4f46\u4e0d\u9650\u4e8e<\/span>Crohn<\/span>\u2019<\/span>s<\/span>\u75c5\u3001\u6e83\u75a1\u6027\u7ed3\u80a0\u708e\u3001\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\u3001\u7ed3\u8282\u75c5\u3001<\/span>Wegener<\/span>\u7efc\u5408\u5f81\uff08\u591a\u8840\u7ba1\u708e\u7684\u8089\u82bd\u80bf\u75c5\u3001<\/span>Graves’<\/span>\u75c5\u3001\u7c7b\u98ce\u6e7f\u5173\u8282\u708e\u3001\u4e0b\u5782\u4f53\u708e\u3001\u773c\u8272\u7d20\u5c42\u708e\uff09\u3001\u81ea\u8eab\u514d\u75ab\u6027\u809d\u708e\u3001\u7cfb\u7edf\u6027\u786c\u5316\u75c5\uff08\u786c\u76ae\u75c5\u7b49\uff09\u3001\u6865\u672c\u6c0f\u7532\u72b6\u817a\u708e\uff08\u4f8b\u5916\u60c5\u51b5\u89c1\u4e0b\u6587\uff09\u3001\u81ea\u8eab\u514d\u75ab\u6027\u8840\u7ba1\u708e\u3001\u81ea\u8eab\u514d\u75ab\u6027\u795e\u7ecf\u75c5\u53d8\uff08<\/span>Guillain-Barre<\/span>\u7efc\u5408\u5f81\uff09\u7b49\u3002\u4f46\u4e0b\u5217\u60c5\u51b5\u9664\u5916\uff1a<\/span>I<\/span>\u578b\u7cd6\u5c3f\u75c5\u3001\u6fc0\u7d20\u66ff\u4ee3\u6cbb\u7597\u7a33\u5b9a\u7684\u7532\u72b6\u817a\u529f\u80fd\u51cf\u9000\u75c7\uff08\u5305\u62ec\u81ea\u8eab\u514d\u75ab\u6027\u7532\u72b6\u817a\u75c5\u5bfc\u81f4\u7684\u7532\u72b6\u817a\u529f\u80fd\u51cf\u9000\u75c7\uff09\u3001\u4e0d\u9700\u8981\u5168\u8eab\u6cbb\u7597\u7684\u94f6\u5c51\u75c5\u6216\u767d\u765c\u98ce\uff1b<\/span><\/span><\/p>\n

10  E10. <\/span>\u9996\u6b21\u7ed9\u836f\u524d<\/span>5<\/span>\u5e74\u5185\u5408\u5e76\u5176\u4ed6\u6076\u6027\u80bf\u7624\uff0c\u9664\u5916\u5df2\u6cbb\u6108\u7684\u76ae\u80a4\u9cde\u764c\u3001\u57fa\u5e95\u7ec6\u80de\u764c\u3001\u6d45\u8868\u6027\u8180\u80f1\u764c\u3001\u539f\u4f4d\u524d\u5217\u817a<\/span>\/<\/span>\u5bab\u9888<\/span>\/<\/span>\u4e73\u817a\u764c\uff1b<\/span><\/span><\/p>\n

11  E11.<\/span>\u60a3\u6709\u672a\u7ecf\u63a7\u5236\u7684\u5408\u5e76\u75c7\uff0c\u5305\u62ec\u4f46\u4e0d\u9650\u4e8e\u4ee5\u4e0b\u60c5\u51b5\u6d3b\u52a8\u6027<\/span>HBV<\/span>\u6216<\/span>HCV<\/span>\u611f\u67d3\uff1b\u5df2\u77e5<\/span>HIV<\/span>\u611f\u67d3\u6216<\/span>AIDS<\/span>\u75c5\u53f2\uff1b\u6d3b\u52a8\u6027\u7ed3\u6838\u75c5\uff1b\u6d3b\u52a8\u6027\u611f\u67d3\u6216\u672c\u7814\u7a76\u7ed9\u836f\u524d<\/span>28<\/span>\u5929\u5185\u7cfb\u7edf\u6027\u4f7f\u7528\u6297\u611f\u67d3\u836f\u7269\uff1b\u672a\u80fd\u63a7\u5236\u7684\u9ad8\u8840\u538b\uff08\u4f11\u606f\u72b6\u6001\u4e0b\u7684\u8840\u538b\u2265<\/span>150\/95 mmHg<\/span>\uff09\u3001\u75c7\u72b6\u6027\u5fc3\u529f\u80fd\u4e0d\u5168\uff08<\/span>NYHA II-IV<\/span>\uff09\u3001<\/span>6<\/span>\u4e2a\u6708\u5185\u7f79\u60a3\u4e0d\u7a33\u5b9a\u578b\u5fc3\u7ede\u75db\u6216\u5fc3\u808c\u6897\u585e\u3001\u6216\u5b58\u5728<\/span>QTc<\/span>\u5ef6\u957f\u6216\u5fc3\u7387\u5931\u5e38\u98ce\u9669\uff08\u57fa\u7ebf<\/span>QTc>470msec <\/span>\u3001\u4f4e\u94be\u8840\u75c7\u3001\u957f<\/span>QT<\/span>\u7efc\u5408\u5f81\u3001\u4f11\u606f\u72b6\u6001\u4e0b\u7684\u5fc3\u7387<\/span>>100 bpm<\/span>\u7684\u623f\u98a4\u6216\u4e25\u91cd\u7684\u5fc3\u74e3\u819c\u75c5\uff09\uff1b\u6d3b\u52a8\u6027\u80c3\u6e83\u75a1\u3001\u80c3\u708e\u6216\u80c3\u51fa\u8840\uff1b<\/span><\/span><\/p>\n

12  E12. <\/span>\u65e2\u5f80\u6297\u80bf\u7624\u6cbb\u7597\u7684\u6bd2\u6027\u672a\u6062\u590d\u81f3<\/span>CTCAE<\/span>\u2264<\/span>1<\/span>\u7ea7\uff08<\/span>NCI-CTCAE v5.0<\/span>\uff09\uff0c\u9664\u5916\u79c3\u53d1\uff08\u5141\u8bb8\u4efb\u4f55\u7ea7\u522b\uff09\u548c\u5916\u5468\u795e\u7ecf\u75c5\u53d8\uff08\u9700\u6062\u590d\u81f3\u2264<\/span>2<\/span>\u7ea7\uff09\uff1b<\/span><\/span><\/p>\n

13  E13. <\/span>\u65e2\u5f80\u5f02\u57fa\u56e0\u9aa8\u9ad3\u6216\u5668\u5b98\u79fb\u690d\u75c5\u53f2\uff1b<\/span><\/span><\/p>\n

14  E14. <\/span>\u65e2\u5f80\u5bf9\u6297\u4f53\u7c7b\u836f\u7269\u8fc7\u654f\u53cd\u5e94\u3001\u9ad8\u654f\u53cd\u5e94\u3001\u4e0d\u8010\u53d7\u75c5\u53f2\uff1b\u65e2\u5f80\u5bf9\u836f\u7269\u660e\u663e\u8fc7\u654f\uff08\u4f8b\u5982\u4e25\u91cd\u8fc7\u654f\u53cd\u5e94\u3001\u514d\u75ab\u4ecb\u5bfc\u7684\u809d\u6bd2\u6027\u3001\u514d\u75ab\u4ecb\u5bfc\u7684\u8840\u5c0f\u677f\u51cf\u5c11\u75c7\u6216\u8d2b\u8840\uff09\uff1b<\/span><\/span><\/p>\n

15  E15. <\/span>\u6000\u5b55\u548c<\/span>\/<\/span>\u6216\u54fa\u4e73\u671f\u5973\u6027\uff1b\u6d3b\u52a8\u6027\u80c3\u6e83\u75a1\u3001\u80c3\u708e\u6216\u80c3\u51fa\u8840\uff1b<\/span><\/span><\/p>\n

16  E16. <\/span>\u5176\u4ed6\u7814\u7a76\u8005\u8ba4\u4e3a\u4f1a\u5f71\u54cd\u672c\u7814\u7a76\u836f\u7269\u6cbb\u7597\u5b89\u5168\u6027\u6216\u4f9d\u4ece\u6027\u7684\u60c5\u51b5\uff0c\u5305\u62ec\u4f46\u4e0d\u9650\u4e8e\u7cbe\u795e\u7c7b\u75be\u75c5\u3001\u672a\u63a7\u5236\u7684\u5927\u91cf\u6d46\u819c\u8154\u79ef\u6db2\u6216\u9700\u8981\u53cd\u590d\u5f15\u6d41\u7684\u4e2d\u5230\u5927\u91cf\u6d46\u819c\u8154\u79ef\u6db2\u5982\u80f8\u6c34\uff0c\u5fc3\u5305\u79ef\u6db2\uff0c\u8179\u6c34\u7b49\u3002<\/span><\/span><\/p>\n

 <\/span><\/p>\n

6.       <\/span><\/span>\u7814\u7a76\u8005\u4fe1\u606f<\/span><\/span><\/p>\n\n\n\n\n\n
\n

\u59d3\u540d<\/span><\/p>\n<\/td>\n

\n

\u5468\u5f69\u5b58\uff0c\u533b\u5b66\u535a\u58eb<\/span><\/p>\n<\/td>\n

\n

\u804c\u79f0<\/span><\/p>\n<\/td>\n

\n

\u4e3b\u4efb\u533b\u5e08<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u90ae\u653f\u5730\u5740<\/span><\/p>\n<\/td>\n

\n

\u4e2d\u56fd\u4e0a\u6d77\u6768\u6d66\u533a\u653f\u6c11\u8def507\u53f7<\/span><\/p>\n<\/td>\n

\n

\u90ae\u7f16<\/span><\/p>\n<\/td>\n

\n

200433<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

\u5355\u4f4d\u540d\u79f0<\/span><\/p>\n<\/td>\n

\n

\u4e0a\u6d77\u5e02\u80ba\u79d1\u533b\u9662<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
\n

\u5e8f\u53f7<\/span><\/p>\n<\/td>\n

\n

\u673a\u6784\u540d\u79f0<\/span><\/p>\n<\/td>\n

\n

\u4e3b\u8981\u7814\u7a76\u8005<\/span><\/p>\n<\/td>\n

\n

\u56fd\u5bb6<\/span><\/p>\n<\/td>\n

\n

\u7701\uff08\u5dde\uff09<\/span><\/p>\n<\/td>\n

\n

\u57ce\u5e02<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

1<\/span><\/p>\n<\/td>\n

\n

\u6d59\u6c5f\u5927\u5b66\u9644\u5c5e\u7b2c\u4e00\u533b\u9662<\/span><\/p>\n<\/td>\n

\n

\u5468\u5efa\u82f1<\/span><\/p>\n<\/td>\n

\n

\u4e2d\u56fd<\/span><\/p>\n<\/td>\n

\n

\u6d59\u6c5f<\/span><\/p>\n<\/td>\n

\n

\u676d\u5dde<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

2<\/span><\/p>\n<\/td>\n

\n

\u6d59\u6c5f\u7701\u80bf\u7624\u533b\u9662<\/span><\/p>\n<\/td>\n

\n

\u8303\u4e91<\/span><\/p>\n<\/td>\n

\n

\u4e2d\u56fd<\/span><\/p>\n<\/td>\n

\n

\u6d59\u6c5f<\/span><\/p>\n<\/td>\n

\n

\u676d\u5dde<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

3<\/span><\/p>\n<\/td>\n

\n

\u6cb3\u5357\u7701\u80bf\u7624\u533b\u9662<\/span><\/p>\n<\/td>\n

\n

\u9a6c\u5fd7\u52c7<\/span><\/p>\n<\/td>\n

\n

\u4e2d\u56fd<\/span><\/p>\n<\/td>\n

\n

\u6cb3\u5357<\/span><\/p>\n<\/td>\n

\n

\u90d1\u5dde<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

4<\/span><\/p>\n<\/td>\n

\n

\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662<\/span><\/p>\n<\/td>\n

\n

\u65b9\u5065<\/span><\/p>\n<\/td>\n

\n

\u4e2d\u56fd<\/span><\/p>\n<\/td>\n

\n

\u5317\u4eac<\/span><\/p>\n<\/td>\n

\n

\u5317\u4eac<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

5<\/span><\/p>\n<\/td>\n

\n

\u90d1\u5dde\u5927\u5b66\u9644\u5c5e\u7b2c\u4e00\u533b\u9662<\/span><\/p>\n<\/td>\n

\n

\u674e\u9192\u4e9a<\/span><\/p>\n<\/td>\n

\n

\u4e2d\u56fd<\/span><\/p>\n<\/td>\n

\n

\u6cb3\u5357<\/span><\/p>\n<\/td>\n

\n

\u90d1\u5dde<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

6<\/span><\/p>\n<\/td>\n

\n

\u798f\u5efa\u7701\u80bf\u7624\u533b\u9662<\/span><\/p>\n<\/td>\n

\n

\u9ec4\u8bda<\/span><\/p>\n<\/td>\n

\n

\u4e2d\u56fd<\/span><\/p>\n<\/td>\n

\n

\u798f\u5efa<\/span><\/p>\n<\/td>\n

\n

\u798f\u5dde<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

7<\/span><\/p>\n<\/td>\n

\n

\u798f\u5efa\u7701\u80ba\u79d1\u533b\u9662<\/span><\/p>\n<\/td>\n

\n

\u9648\u7fa4<\/span><\/p>\n<\/td>\n

\n

\u4e2d\u56fd<\/span><\/p>\n<\/td>\n

\n

\u798f\u5efa<\/span><\/p>\n<\/td>\n

\n

\u798f\u5dde<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

8<\/span><\/p>\n<\/td>\n

\n

\u5f90\u5dde\u5e02\u4e2d\u5fc3\u533b\u9662<\/span><\/p>\n<\/td>\n

\n

\u5b59\u4e09\u5143<\/span><\/p>\n<\/td>\n

\n

\u4e2d\u56fd<\/span><\/p>\n<\/td>\n

\n

\u6c5f\u82cf<\/span><\/p>\n<\/td>\n

\n

\u5f90\u5dde<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

9<\/span><\/p>\n<\/td>\n

\n

\u5e7f\u897f\u533b\u79d1\u5927\u5b66\u80bf\u7624\u533b\u9662<\/span><\/p>\n<\/td>\n

\n

\u4e8e\u8d77\u6d9b<\/span><\/p>\n<\/td>\n

\n

\u4e2d\u56fd<\/span><\/p>\n<\/td>\n

\n

\u5e7f\u897f<\/span><\/p>\n<\/td>\n

\n

\u5357\u5b81<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/span><\/p>\n


<\/p>\n

\n
\n
\n
\u4e34\u5e8a\u8bd5\u9a8c\u62a5\u540d\u65b9\u5f0f<\/span><\/section>\n

<\/section>\n<\/section>\n<\/section>\n<\/section>\n


<\/p>\n

<\/section>\n

\u626b\u63cf\u4e0b\u65b9\u4e8c\u7ef4\u7801\uff0c\u56de\u590d\u201c\u5165\u7ec4\u201d\u5373\u53ef<\/strong><\/span><\/span><\/p>\n

\u2193<\/strong>\u2193<\/strong>\u2193<\/strong>\u2193<\/strong><\/strong><\/span><\/span><\/p>\n

\"\u3010PDL-1\/CTAL-4\u53cc\u6297\u62db\u52df\u60a3\u8005\u3011\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u53d7\u8bd5\u8005\u4e2d\u7684\u6709\u6548\u6027\u3001\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027<\/p>\n


<\/p>\n

\"\u3010PDL-1\/CTAL-4\u53cc\u6297\u62db\u52df\u60a3\u8005\u3011\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u53d7\u8bd5\u8005\u4e2d\u7684\u6709\u6548\u6027\u3001\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u70b9\u51fb\u201c<\/span>\u9605\u8bfb\u539f\u6587<\/span>\u201d\u67e5\u770b\u8be6\u60c5<\/span><\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

\u70b9\u51fb\u9a6c\u4e0a\u5165\u7ec4\u4e34\u5e8a\u8bd5\u9a8c \u516c\u4f17\u53f7\uff1ashiyan589 \u6297\u764c\u6307\u5357\u70b9\u51fb\u4e0b\u65b9 \u2193\u2193\u2193 \u5165\u7ec4\u62a5\u540d\u65b9\u5f0f\u89c1\u6587\u672b \u2193\u2193\u2193\u2193 1. […]<\/p>\n","protected":false},"author":1,"featured_media":88831,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/88830"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=88830"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/88830\/revisions"}],"predecessor-version":[{"id":88840,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/88830\/revisions\/88840"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/88831"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=88830"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=88830"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=88830"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}