{"id":89596,"date":"2019-04-18T00:00:50","date_gmt":"2019-04-23T04:10:54","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/89596\/"},"modified":"2019-04-23T12:10:57","modified_gmt":"2019-04-23T04:10:57","slug":"c979f307e2","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/89596\/","title":{"rendered":"\u8c6a\u68ee\u7b2c\u4e09\u4ee3 EGFR-TKI\u300c\u5965\u7f8e\u66ff\u5c3c\u300d\u62a5\u4e0a\u5e02\uff01"},"content":{"rendered":"
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4 \u6708 18 \u65e5\uff0cInsight \u6570\u636e\u5e93\uff08https:\/\/db.dxy.cn\uff09\u663e\u793a\uff0c\u6c5f\u82cf\u8c6a\u68ee 1 \u7c7b\u65b0\u836f\u300c\u5965\u7f8e\u66ff\u5c3c\u300d\u7684\u4e0a\u5e02\u7533\u8bf7\u83b7 CDE \u627f\u529e\uff0c\u53d7\u7406\u53f7 CXHS1900011\uff0c\u8be5\u836f\u4f5c\u4e3a\u7b2c\u4e09\u4ee3 EGFR-TKI\uff0c\u7528\u4e8e\u6cbb\u7597\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\u3002<\/span><\/p>\n


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\"\u8c6a\u68ee\u7b2c\u4e09\u4ee3<\/p>\n


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\"\u8c6a\u68ee\u7b2c\u4e09\u4ee3<\/p>\n

 EGFR-TKI \u9776\u70b9\u662f\u4ec0\u4e48<\/strong><\/p>\n


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EGFR-TKI \u662f\u8868\u76ae\u957f\u56e0\u5b50\u53d7\u4f53\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242\uff0c\u662f\u6cbb\u7597 NSCLC \u6700\u5e38\u7528\u7684\u9776\u5411\u836f\u7269\uff0c\u76ee\u524d\u5df2\u7ecf\u7814\u53d1\u81f3\u7b2c\u4e09\u4ee3\u3002<\/span>
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\"\u8c6a\u68ee\u7b2c\u4e09\u4ee3<\/p>\n


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\u51e0\u4e4e\u6240\u6709 EGFR-TKI \u6cbb\u7597\u6709\u6548\u7684\u60a3\u8005\u6700\u7ec8\u5747\u4ea7\u751f\u83b7\u5f97\u6027\u8010\u836f\u3002<\/span>\u6700\u5e38\u89c1\u7684\u8010\u836f\u673a\u5236\u662f EGFR 20 \u5916\u663e\u5b50\u7b2c 790 \u4f4d\u70b9\u4e0a\u7684\u82cf\u6c28\u9178\u4e3a\u86cb\u6c28\u9178\u6240\u53d6\u4ee3 (T790M)\uff0c\u4ece\u800c\u6539\u53d8\u4e86\u4e09\u78f7\u9178\u817a\u82f7\u7684\u4eb2\u548c\u6027\uff0c\u5bfc\u81f4 EGFR-TKI \u4e0d\u80fd\u6709\u6548\u963b\u65ad\u4fe1\u53f7\u901a\u8def\u800c\u4ea7\u751f\u8010\u836f\u3002<\/span><\/p>\n


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\u7b2c\u4e09\u4ee3 EGFR-TKI \u4e3a\u4e0d\u53ef\u9006\u7684\u9009\u62e9\u6027 TKI\uff0c\u81f4\u529b\u4e8e\u514b\u670d T790M \u4ecb\u5bfc\u7684\u836f\u7269\u62b5\u6297\uff0c\u4ee5\u5176\u4f18\u5f02\u7684\u4e34\u5e8a\u7597\u6548\u5df2\u662f EGFR \u7a81\u53d8 NSCLC \u4e00\u7ebf\u6cbb\u7597\u7684\u65b0\u6807\u51c6\u3002<\/span><\/p>\n


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2018 \u5e74 10 \u6708 10 \u65e5\uff0c\u5965\u897f\u66ff\u5c3c\u88ab\u7eb3\u5165\u4e86\u300a\u56fd\u5bb6\u57fa\u672c\u533b\u7597\u4fdd\u9669\u3001\u5de5\u4f24\u4fdd\u9669\u548c\u751f\u80b2\u4fdd\u9669\u836f\u54c1\u76ee\u5f55\u300b\u4e59\u7c7b\u8303\u56f4\u3002<\/span><\/p>\n


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\"\u8c6a\u68ee\u7b2c\u4e09\u4ee3<\/p>\n

<\/span>\u56fd\u4ea7\u7b2c\u4e09\u4ee3 EGFR-TKI \u7684\u7814\u53d1\u68af\u961f<\/span><\/strong><\/p>\n


<\/p>\n

\u76ee\u524d\uff0c\u56fd\u4ea7\u7b2c\u4e09\u4ee3 EGFR-TKI \u7684\u7814\u53d1\u68af\u961f\u4e2d\uff0c\u6d59\u6c5f\u827e\u68ee\u836f\u4e1a\u9886\u5148<\/strong>\uff0c\u5176\u7533\u62a5\u7684 1 \u7c7b\u65b0\u836f\u4e8e 2018 \u5e74 6 \u6708 14 \u65e5\u62a5\u4e0a\u5e02\uff0c\u5e76\u4e8e 2018 \u5e74 8 \u6708 17 \u65e5\u7eb3\u5165\u4f18\u5148\u5ba1\u8bc4\uff0c\u76ee\u524d CDE \u5df2\u7ecf\u53d1\u9001\u901a\u77e5\uff1b\u6c5f\u82cf\u8c6a\u68ee\u4e3a\u56fd\u4ea7\u7b2c\u4e8c\u5bb6\u62a5\u4ea7\u7684\u4f01\u4e1a\uff0c\u6709\u671b\u7eb3\u5165\u4f18\u5148\u5ba1\u6279\u3002<\/span><\/p>\n


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\u7f8e\u56fd\u4e13\u5229\u5c40\u663e\u793a\uff0c\u963f\u65af\u5229\u5eb7\u5965\u897f\u66ff\u5c3c\u7684\u5316\u5408\u7269\u4e13\u5229\u8981\u5230 2032 \u5e74 7 \u6708 25 \u65e5\u5230\u671f\uff0c\u6b63\u5904\u4e8e\u4e13\u5229\u9f0e\u76db\u65f6\u671f\uff1b\u8c6a\u68ee\u836f\u4e1a\u7684\u5965\u7f8e\u66ff\u5c3c\u53ca\u6d59\u6c5f\u827e\u68ee\u827e\u7ef4\u66ff\u5c3c<\/span>\u5747\u62e5\u6709\u5168\u7403\u5316\u5408\u7269\u4e13\u5229\uff0c\u53ef\u4ee5\u5728\u5965\u897f\u66ff\u5c3c<\/span>\u4e13\u5229\u5230\u671f\u524d\u62a2\u5360\u5e02\u573a\u3002<\/span><\/p>\n

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\"\u8c6a\u68ee\u7b2c\u4e09\u4ee3
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\"\u8c6a\u68ee\u7b2c\u4e09\u4ee3<\/p>\n


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\"\u8c6a\u68ee\u7b2c\u4e09\u4ee3<\/p>\n


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\"\u8c6a\u68ee\u7b2c\u4e09\u4ee3<\/span><\/span><\/a><\/p>\n

\"\u8c6a\u68ee\u7b2c\u4e09\u4ee3<\/span><\/span><\/a><\/p>\n

\u70b9\u4e2a\u597d\u770b\uff0c\u8bc1\u660e\u6765\u8fc7<\/span>\"\u8c6a\u68ee\u7b2c\u4e09\u4ee3<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

4 \u6708 18 \u65e5\uff0cInsight \u6570\u636e\u5e93\uff08https:\/\/db.dxy.cn\uff09\u663e\u793a\uff0c\u6c5f\u82cf\u8c6a\u68ee 1 \u7c7b\u65b0\u836f\u300c\u5965\u7f8e […]<\/p>\n","protected":false},"author":1,"featured_media":89597,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/89596"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=89596"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/89596\/revisions"}],"predecessor-version":[{"id":89608,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/89596\/revisions\/89608"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/89597"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=89596"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=89596"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=89596"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}