{"id":89944,"date":"2019-04-17T00:00:50","date_gmt":"2019-04-23T04:14:28","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/89944\/"},"modified":"2019-04-23T12:14:29","modified_gmt":"2019-04-23T04:14:29","slug":"e9f34edd10","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/89944\/","title":{"rendered":"\u57fa\u56e0\u68c0\u6d4b\u89e3\u8bfb\u79d8\u7c4d\u5341\u4e00:\u5982\u4f55\u770b\u5f85\u201c\u4e34\u5e8a\u610f\u4e49\u672a\u660e\u201d\uff1f"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"text-align: center;\"><img class=\"rich_pages\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/8-1555992868.jpeg\" alt=\"\u57fa\u56e0\u68c0\u6d4b\u89e3\u8bfb\u79d8\u7c4d\u5341\u4e00:\u5982\u4f55\u770b\u5f85\u201c\u4e34\u5e8a\u610f\u4e49\u672a\u660e\u201d\uff1f\" title=\"\u57fa\u56e0\u68c0\u6d4b\u89e3\u8bfb\u79d8\u7c4d\u5341\u4e00:\u5982\u4f55\u770b\u5f85\u201c\u4e34\u5e8a\u610f\u4e49\u672a\u660e\u201d\uff1f\"  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style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\u5efa\u7acb\u957f\u671f\u968f\u8bbf<\/strong>\u3002\u4f8b\u5982\uff0c\u5728MYH7\u57fa\u56e0\u89e3\u8bfb\u6307\u5357\u4e2d\uff0c\u5982\u6709\u5927\u4e8e\u7b49\u4e8e6\u4e2a\u5148\u8bc1\u8005\u5e26\u6709\u76f8\u540c\u7684\u8868\u578b\uff0c\u5219\u7b97\u4f5c\u4e00\u4e2a\u81f4\u75c5\u8bc1\u636e<span style=\"max-width: 100%;box-sizing: border-box;letter-spacing: 0px;word-wrap: break-word 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100%;box-sizing: border-box;letter-spacing: 0px;word-wrap: break-word !important;\">\u3002\u76ee\u524d\u5f88\u591aVUS\u90fd\u6ca1\u6709\u529e\u6cd5\u83b7\u5f97\u529f\u80fd\u8bc1\u636e\u652f\u6301\uff0c\u8fd9\u662f\u56e0\u4e3a\u86cb\u767d\u529f\u80fd\u7814\u7a76\u8fd8\u6709\u5f88\u591a\u7a7a\u767d\u3002\u800c\u4e14\uff0c\u5df2\u6709\u7684\u5927\u591a\u6570\u52a8\u7269\u6a21\u578b\u5747\u4e3a\u201c\u6572\u9664\uff08knockout\uff09\u201d\u3002\u4f46\u4e34\u5e8a\u68c0\u51fa\u7684\u5927\u591a\u6570\u53d8\u5f02\u90fd\u4e0d\u662fLOF\u53d8\u5f02\uff0c\u800c\u662f\u9519\u4e49\u53d8\u5f02\u3002\u5982\u5e0c\u671b\u786e\u5b9a\u8fd9\u4e9b\u57fa\u56e0\u7684\u53d8\u5f02\uff0c\u9700\u8981\u4f7f\u7528\u201c\u6572\u5165\uff08knockin\uff09\u201d\u3002\u8fd9\u9700\u8981\u529f\u80fd\u5b66\u9886\u57df\u7684\u5b9e\u9a8c\u5ba4\u4e0e\u4e34\u5e8a\u5bc6\u5207\u5408\u4f5c\uff0c\u4ee5\u53ca\u5f00\u53d1\u7b80\u5355\u7ecf\u6d4e\u7684\u65b9\u6cd5\u3002<\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;display: inline-block;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: middle;word-wrap: break-word !important;\">\n<section style=\"margin-bottom: -5px;max-width: 100%;box-sizing: border-box;width: 0px;transform: rotate(0deg);border-right: 0.56em solid rgb(110, 125, 118);border-top: 0.31em solid transparent;border-bottom: 0.31em solid transparent;word-wrap: break-word !important;\"><\/section>\n<section style=\"max-width: 100%;box-sizing: border-box;width: 0px;border-right: 0.56em solid rgb(236, 170, 104);border-top: 0.31em solid transparent;border-bottom: 0.31em solid transparent;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<section style=\"padding-right: 5px;padding-left: 5px;max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: middle;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\">\u6d4b\u8bd5\u524d\u54a8\u8be2<\/p>\n<\/section>\n<section style=\"max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: middle;word-wrap: break-word !important;\">\n<section style=\"margin-bottom: -5px;max-width: 100%;box-sizing: border-box;width: 0px;transform: rotate(0deg);border-left: 0.56em solid rgb(110, 125, 118);border-top: 0.31em solid transparent;border-bottom: 0.31em solid transparent;word-wrap: break-word !important;\"><\/section>\n<section style=\"max-width: 100%;box-sizing: border-box;width: 0px;border-left: 0.56em solid rgb(236, 170, 104);border-top: 0.31em solid transparent;border-bottom: 0.31em solid transparent;word-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\">\u8fd9\u6b21\u5e74\u4f1a\u4e13\u5bb6\u63d0\u51fa\u201c\u6d4b\u8bd5\u524d\u54a8\u8be2\u201d\u7684\u91cd\u8981\u6027\u3002\u5176\u4e2d\u5f88\u91cd\u8981\u7684\u4e00\u70b9\uff0c\u662f\u5728\u68c0\u6d4b\u524d\u544a\u77e5\u60a3\u8005\uff1a\u533b\u5b66\u5c1a\u4e14\u5904\u5728\u53d1\u5c55\u9636\u6bb5\uff0c\u76ee\u524d\u57fa\u56e0\u68c0\u6d4b\u4ecd\u7136\u6709\u5f88\u591a\u4e0d\u786e\u5b9a\u6027\u56e0\u7d20\u5728\u91cc\u9762\uff0c\u4e5f\u5c31\u662f\u4f1a\u51fa\u73b0VUS\u53d8\u5f02\u3002\u5f53\u7136\uff0c\u5982\u4e0a\u6240\u8ff0\uff0c\u4e5f\u6709\u7684\u573a\u666f\u9009\u62e9\u4e0d\u544a\u8bc9\u60a3\u8005VUS\u7684\u60c5\u51b5\u3002\u7a76\u7adf\u5982\u4f55\u5904\u7406\uff0c\u5e0c\u671b\u80fd\u968f\u7740\u9057\u4f20\u54a8\u8be2\u8fdb\u4e00\u6b65\u53d1\u5c55\uff0c\u53ef\u4ee5\u542c\u5230\u66f4\u591a\u4e13\u5bb6\u8ba8\u8bba\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;vertical-align: middle;display: inline-block;line-height: 0;width: 473.889px;word-wrap: break-word !important;\"><img class=\"\"   width=\"100%\"   style=\"box-sizing: border-box;vertical-align: middle;width: 473.889px;word-wrap: break-word !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/5-1555992869.jpeg\" alt=\"\u57fa\u56e0\u68c0\u6d4b\u89e3\u8bfb\u79d8\u7c4d\u5341\u4e00:\u5982\u4f55\u770b\u5f85\u201c\u4e34\u5e8a\u610f\u4e49\u672a\u660e\u201d\uff1f\" title=\"\u57fa\u56e0\u68c0\u6d4b\u89e3\u8bfb\u79d8\u7c4d\u5341\u4e00:\u5982\u4f55\u770b\u5f85\u201c\u4e34\u5e8a\u610f\u4e49\u672a\u660e\u201d\uff1f\"  \/><\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;font-size: 14px;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\u53c2\u8003\u6587\u732e<\/strong><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\">[1]&nbsp;https:\/\/bbs.genelinks.com\/thread-1246-1-1.html<\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\">[2]&nbsp;<span style=\"max-width: 100%;box-sizing: border-box;letter-spacing: 0px;word-wrap: break-word !important;\">Kelly&nbsp;M&nbsp;A,&nbsp;Caleshu&nbsp;C,&nbsp;Morales&nbsp;A,&nbsp;et&nbsp;al.&nbsp;Adaptation&nbsp;and&nbsp;validation&nbsp;of&nbsp;the&nbsp;ACMG\/AMP&nbsp;variant&nbsp;classification&nbsp;framework&nbsp;for&nbsp;MYH7&nbsp;-associated&nbsp;inherited&nbsp;cardiomyopathies:&nbsp;recommendations&nbsp;by&nbsp;ClinGen\u2019s&nbsp;Inherited&nbsp;Cardiomyopathy&nbsp;Expert&nbsp;Panel[J].&nbsp;Genetics&nbsp;in&nbsp;Medicine,&nbsp;2018,&nbsp;20(3):&nbsp;351-359.<\/span><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"margin-bottom: 10px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);display: inline-block;vertical-align: bottom;width: 487.431px;word-wrap: break-word !important;\">\n<section  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;width: 2.25em;height: 2.25em;border-left: 5px solid rgb(239, 134, 100);border-top: 5px solid rgb(239, 134, 100);word-wrap: break-word !important;\"><\/section>\n<section style=\"margin-top: -2.25em;margin-left: 5px;padding-top: 5px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;background-color: rgb(247, 247, 247);word-wrap: break-word !important;\">\n<section  style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"padding: 10px;max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;text-align: center;font-size: 12px;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\">\u5feb\u5173\u6ce8\u4e0d\u80b2\u8bc6\u9057\u516c\u4f17\u53f7\uff0c\u4e00\u8d77\u6da8\u59ff\u52bf\uff01<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;white-space: normal;line-height: 27.2px;background-color: rgb(255, 255, 255);box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 82, 255);text-decoration: underline;-webkit-tap-highlight-color: rgba(0, 0, 0, 0);box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIwMTQ3MDc4Mw==&amp;mid=2247496617&amp;idx=2&amp;sn=a79117e5e33ff48fe9a398a45df56dfa&amp;chksm=96efd5f9a1985cefcdd67d66c14617a4895b77a5ae7c58c2d26f0b885c25c079c3049e7e988c&amp;scene=21#wechat_redirect\" target=\"_blank\"  style=\"color: rgb(0, 82, 255);-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\u52a0\u5165\u57fa\u56e0\u4ff1\u4e50\u90e8&nbsp; &nbsp; \u6210\u5c31\u884c\u4e1a\u7cbe\u82f1<\/a><\/strong><\/span><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;white-space: normal;line-height: 27.2px;text-align: center;background-color: rgb(255, 255, 255);box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIwMTQ3MDc4Mw==&amp;mid=2247496633&amp;idx=3&amp;sn=8bf712ae6832e2d24e30dd2deff39b28&amp;chksm=96efd5e9a1985cffb76fa308e0cd93fe8872ad4344286f0a1679108528b2c5499ed808d44cee&amp;scene=21#wechat_redirect\" target=\"_blank\"  style=\"text-decoration: underline;-webkit-tap-highlight-color: rgba(0, 0, 0, 0);max-width: 100%;line-height: 0;top: auto;left: auto;right: auto;bottom: auto;font-size: 16px;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><span style=\"max-width: 100%;line-height: 0;top: auto;left: auto;right: auto;bottom: auto;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><span class=\"js_jump_icon h5_image_link\"  style=\"max-width: 100%;line-height: 0;top: auto;left: auto;right: auto;bottom: auto;box-sizing: border-box !important;word-wrap: break-word !important;\"><img class=\"\"      width=\"677px\"  style=\"box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;visibility: visible !important;width: 676px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/9-1555992869.jpeg\" alt=\"\u57fa\u56e0\u68c0\u6d4b\u89e3\u8bfb\u79d8\u7c4d\u5341\u4e00:\u5982\u4f55\u770b\u5f85\u201c\u4e34\u5e8a\u610f\u4e49\u672a\u660e\u201d\uff1f\" title=\"\u57fa\u56e0\u68c0\u6d4b\u89e3\u8bfb\u79d8\u7c4d\u5341\u4e00:\u5982\u4f55\u770b\u5f85\u201c\u4e34\u5e8a\u610f\u4e49\u672a\u660e\u201d\uff1f\"  \/><\/span><\/span><\/a><\/p>\n<p style=\"max-width: 100%;min-height: 1em;letter-spacing: 0.544px;white-space: normal;line-height: 27.2px;text-align: left;background-color: rgb(255, 255, 255);box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><img class=\"\"      width=\"533px\"  style=\"box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;visibility: visible !important;width: 533px !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/4-1555992869-1.jpeg\" alt=\"\u57fa\u56e0\u68c0\u6d4b\u89e3\u8bfb\u79d8\u7c4d\u5341\u4e00:\u5982\u4f55\u770b\u5f85\u201c\u4e34\u5e8a\u610f\u4e49\u672a\u660e\u201d\uff1f\" title=\"\u57fa\u56e0\u68c0\u6d4b\u89e3\u8bfb\u79d8\u7c4d\u5341\u4e00:\u5982\u4f55\u770b\u5f85\u201c\u4e34\u5e8a\u610f\u4e49\u672a\u660e\u201d\uff1f\"  \/><\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u5f53\u4e00\u4e2a\u53d8\u5f02\u6ca1\u6709\u529e\u6cd5\u5f52\u4e3a\u201c\u81f4\u75c5\u7684\u201d\u3001\u201c\u53ef\u80fd\u81f4\u75c5\u7684\u201d\uff0c\u6216\u8005\u201c\u826f\u6027\u7684\u201d\u3001\u201c\u53ef\u80fd\u826f\u6027\u7684\u201d\u65f6\uff0c\u4f1a\u88ab\u5224\u5b9a\u4e3a\u201c\u4e34\u5e8a\u610f\u4e49\u4e0d\u660e\u786e [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":89945,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/89944"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=89944"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/89944\/revisions"}],"predecessor-version":[{"id":89951,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/89944\/revisions\/89951"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/89945"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=89944"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=89944"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=89944"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}