{"id":89990,"date":"2019-04-17T00:00:50","date_gmt":"2019-04-23T04:14:54","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/89990\/"},"modified":"2019-04-23T12:14:57","modified_gmt":"2019-04-23T04:14:57","slug":"748859337c","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/89990\/","title":{"rendered":"\u3010\u5b66\u672f\u7814\u7a76\u3011NGS\u52a9\u529b\u65b0\u6297\u539f\u4e2a\u4f53\u5316\u514d\u75ab\u6cbb\u7597\u65b0\u6280\u672f\u7814\u7a76"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<p style=\"text-align: center;\"><img class=\"rich_pages\"       style=\"\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/6-1555992894.jpeg\" alt=\"\u3010\u5b66\u672f\u7814\u7a76\u3011NGS\u52a9\u529b\u65b0\u6297\u539f\u4e2a\u4f53\u5316\u514d\u75ab\u6cbb\u7597\u65b0\u6280\u672f\u7814\u7a76\" title=\"\u3010\u5b66\u672f\u7814\u7a76\u3011NGS\u52a9\u529b\u65b0\u6297\u539f\u4e2a\u4f53\u5316\u514d\u75ab\u6cbb\u7597\u65b0\u6280\u672f\u7814\u7a76\"  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style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\">\u8fd1\u65e5\uff0c\u5357\u4eac\u5927\u5b66\u533b\u5b66\u9662\u9644\u5c5e\u9f13\u697c\u533b\u9662\u80bf\u7624\u4e2d\u5fc3<strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\u5218\u5b9d\u745e<\/strong>\u6559\u6388\u56e2\u961f\u7684<strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\u9648\u4eff\u519b<\/strong>\u535a\u58eb\u4f5c\u4e3a<strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\u7b2c\u4e00\u4f5c\u8005<\/strong>\u5728\u56fd\u9645\u77e5\u540d\u671f\u520a<strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">Journal of Clinical Investigation\uff08JCI, IF=13.251\uff09<\/strong>\u4e0a\u53d1\u8868\u4e86\u4e00\u9879<strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word 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style=\"max-width: 100%;box-sizing: border-box;font-size: 16px;word-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: top;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;width: 43px;word-wrap: break-word !important;\">\n<section style=\"margin-bottom: 3px;max-width: 100%;box-sizing: border-box;width: 5px;height: 5px;background-color: rgb(60, 133, 217);word-wrap: break-word !important;\"><\/section>\n<section style=\"margin-bottom: -6px;margin-left: 3px;max-width: 100%;box-sizing: border-box;width: 40px;height: 1px;background-color: rgb(114, 114, 114);word-wrap: break-word !important;\"><\/section>\n<section style=\"margin-left: 8px;max-width: 100%;box-sizing: border-box;width: 1px;height: 25px;background-color: 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!important;\"><\/section>\n<section style=\"margin-top: 3px;margin-left: auto;max-width: 100%;box-sizing: border-box;width: 5px;height: 5px;background-color: rgb(60, 133, 217);word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word 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break-word !important;\">\n<section style=\"margin-top: 0.5em;margin-bottom: 0.5em;padding-right: 0.5em;padding-left: 0.5em;max-width: 100%;box-sizing: border-box;text-align: center;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;width: 661.024px;box-shadow: rgb(102, 102, 102) 3.2px 3.2px 8px;display: inline-block;line-height: 0;border-color: white;word-wrap: break-word !important;height: auto !important;\"><img class=\"\"        style=\"box-sizing: border-box;vertical-align: middle;width: 661.024px;word-wrap: break-word !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/9-1555992895.jpeg\" alt=\"\u3010\u5b66\u672f\u7814\u7a76\u3011NGS\u52a9\u529b\u65b0\u6297\u539f\u4e2a\u4f53\u5316\u514d\u75ab\u6cbb\u7597\u65b0\u6280\u672f\u7814\u7a76\" title=\"\u3010\u5b66\u672f\u7814\u7a76\u3011NGS\u52a9\u529b\u65b0\u6297\u539f\u4e2a\u4f53\u5316\u514d\u75ab\u6cbb\u7597\u65b0\u6280\u672f\u7814\u7a76\"  \/><\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-align: center;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box;color: rgb(0, 122, 170);font-size: 14px;word-wrap: break-word !important;\">\u56fe1 \u65b0\u6297\u539f\u514d\u75ab\u6cbb\u7597\u7684\u84dd\u56fe\uff08Science\uff09<\/span><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;line-height: 1.5;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box;font-size: 14px;word-wrap: break-word !important;\">\u4ee5\u65b0\u6297\u539f\u4e3a\u57fa\u7840\u7684\u4e2a\u4f53\u5316\u514d\u75ab\u6cbb\u7597\u6a21\u5f0f\u9762\u4e34\u7684\u6700\u5927\u969c\u788d\u5728\u4e8e\u65b0\u6297\u539f\u7684\u7b5b\u67e5\u548c\u5236\u5907\u3002\u76ee\u524d\uff0c\u5305\u62ecCNS\u5728\u5185\u7684\u76f8\u5173\u7814\u7a76\u4e2d\uff0c\u65b0\u6297\u539f\u7684\u7b5b\u9009\u548c\u5236\u5907\u4e3b\u8981\u6709\u4e24\u79cd\u7b56\u7565\uff1a\u2460\u751f\u4fe1\u5206\u6790\u9884\u6d4b\u6570\u5341\u81f3\u6570\u767e\u6761\u6297\u539f\u80bd\uff0c\u5408\u6210\u540e\u901a\u8fc7APC\u8d1f\u8f7d\u7a81\u53d8\u80bd\uff0c\u523a\u6fc0T\u7ec6\u80de\u7b5b\u9009\uff1b\u2461\u6784\u5efa\u591a\u79cd\u7a81\u53d8\u80bd\u5bf9\u5e94\u7684\u4e32\u8054\u5fae\u57fa\u56e0\u8f7d\u4f53\uff0c\u4f53\u5916\u8f6c\u5f55\u4ea7\u751f\u591a\u8868\u4f4dRNA\uff0c\u8f6c\u67d3DC\u540e\u523a\u6fc0T\u7ec6\u80de\u7b5b\u9009\u3002\u4e0a\u8ff0\u4e24\u79cd\u65b9\u5f0f\u7684\u4e3b\u8981\u7f3a\u9677\u662f\u9633\u6027\u7387\u4f4e\u3001\u8017\u65f6\u957f\uff08&gt;103\u5929\uff09\u3001\u82b1\u8d39\u5de8\u5927\uff0c\u96be\u4ee5\u4e34\u5e8a\u8f6c\u5316\u3002<\/span><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box;font-size: 14px;word-wrap: break-word !important;\">&nbsp;<\/span><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box;font-size: 14px;word-wrap: break-word !important;\">\u672c\u7814\u7a76\u4e2d\uff0c\u9648\u4eff\u519b\u535a\u58eb\u5728\u5bfc\u5e08\u5218\u5b9d\u745e\u6559\u6388\u7684\u6307\u5bfc\u4e0b\uff0c\u5efa\u7acb\u4e86\u4e24\u79cd\u65b0\u7684\u66f4\u9ad8\u6548\u7684\u65b0\u6297\u539f\u7b5b\u9009\u65b9\u5f0f\uff1a\u2460\u9ad8\u901a\u91cf\u6d4b\u5e8f\u540e\uff0c\u8fd0\u7528\u6539\u826f\u7684\u6297\u539f\u9884\u6d4b\u7b97\u6cd5\u548c\u66f4\u7075\u654f\u7684\u4f53\u5916\u7b5b\u9009\u65b9\u5f0f\uff0c\u51cf\u5c11\u5019\u9009\u6297\u539f\u80bd\u6570\u91cf\uff0c\u8fdb\u800c\u63d0\u9ad8\u6297\u539f\u9274\u5b9a\u7684\u6210\u529f\u7387\uff1b\u2461\u5efa\u7acb\u5e38\u89c1\u5b9e\u4f53\u80bf\u7624\u76f8\u5173\u7684\u65b0\u6297\u539f\u80bd\u5e93\uff0c\u60a3\u8005\u68c0\u6d4b\u5230\u70ed\u70b9\u7a81\u53d8\u540e\uff0c\u4f7f\u7528\u80bd\u5e93\u6765\u6e90\u7684\u6297\u539f\u8fdb\u884c\u4f53\u5916\u7b5b\u9009\uff0c\u4ece\u800c\u663e\u8457\u7f29\u77ed\u65b0\u6297\u539f\u9274\u5b9a\u7684\u65f6\u957f\uff0810\u5929\uff09\u3002<\/span><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);word-wrap: break-word !important;\">\n<section style=\"margin-top: 0.5em;margin-bottom: 0.5em;padding-right: 0.5em;padding-left: 0.5em;max-width: 100%;box-sizing: border-box;text-align: center;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;width: 661.024px;box-shadow: rgb(102, 102, 102) 0.2em 0.2em 0.5em;display: inline-block;line-height: 0;border-color: white;word-wrap: break-word !important;height: auto !important;\"><img class=\"\"        style=\"box-sizing: border-box;vertical-align: middle;width: 661.024px;word-wrap: break-word !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/4-1555992896.jpeg\" alt=\"\u3010\u5b66\u672f\u7814\u7a76\u3011NGS\u52a9\u529b\u65b0\u6297\u539f\u4e2a\u4f53\u5316\u514d\u75ab\u6cbb\u7597\u65b0\u6280\u672f\u7814\u7a76\" title=\"\u3010\u5b66\u672f\u7814\u7a76\u3011NGS\u52a9\u529b\u65b0\u6297\u539f\u4e2a\u4f53\u5316\u514d\u75ab\u6cbb\u7597\u65b0\u6280\u672f\u7814\u7a76\"  \/><\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;line-height: 1.5;font-size: 15px;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box;font-size: 14px;text-indent: 2em;letter-spacing: 0px;color: rgb(0, 122, 170);word-wrap: break-word !important;\">\u5357\u4eac\u9f13\u697c\u533b\u9662\u80bf\u7624\u4e2d\u5fc3\u901a\u8fc7\u524d\u671f\u7684\u7814\u53d1\u79ef\u7d2f\u5efa\u7acb\u4e86\u65e9\u671f\u80bd\u5e93\uff0c\u65e9\u671f\u80bd\u5e93\u768444\u6761\u65b0\u6297\u539f\u8868\u4f4d\u80bd\u8986\u76d6\u4e869\u79cd\u5e38\u89c1\u5b9e\u4f53\u7624\u4e2d5.11%-83.81%\u7684\u60a3\u8005\u3002\u76ee\u524d\uff0c\u8be5\u4e2d\u5fc3\u7684\u65b0\u6297\u539f\u80bd\u5e93\u5df2\u5347\u7ea7\uff0c\u65b0\u6297\u539f\u8868\u4f4d\u80bd\u5df2\u589e\u81f3100\u6761\u4ee5\u4e0a\u3002<\/span><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);word-wrap: break-word !important;\">\n<section style=\"margin-top: 0.5em;margin-bottom: 0.5em;padding-right: 0.5em;padding-left: 0.5em;max-width: 100%;box-sizing: border-box;text-align: center;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;width: 661.024px;box-shadow: rgb(102, 102, 102) 0.2em 0.2em 0.5em;display: inline-block;line-height: 0;border-color: white;word-wrap: break-word !important;height: auto !important;\"><img class=\"\"        style=\"box-sizing: border-box;vertical-align: middle;width: 661.024px;word-wrap: break-word !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/10-1555992896.jpeg\" alt=\"\u3010\u5b66\u672f\u7814\u7a76\u3011NGS\u52a9\u529b\u65b0\u6297\u539f\u4e2a\u4f53\u5316\u514d\u75ab\u6cbb\u7597\u65b0\u6280\u672f\u7814\u7a76\" title=\"\u3010\u5b66\u672f\u7814\u7a76\u3011NGS\u52a9\u529b\u65b0\u6297\u539f\u4e2a\u4f53\u5316\u514d\u75ab\u6cbb\u7597\u65b0\u6280\u672f\u7814\u7a76\"  \/><\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;line-height: 1.5;font-size: 14px;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 122, 170);box-sizing: border-box !important;word-wrap: break-word !important;\">\u4e00\u4f8b\u591a\u53d1\u8f6c\u79fb\u6027\u80ba\u7ed3\u8282\u60a3\u8005\uff0c\u4e09\u7ebf\u6cbb\u7597\u5931\u8d25\u540e\u63a5\u53d7\u8be5\u80bf\u7624\u4e2d\u5fc3\u4e2a\u4f53\u5316\u65b0\u6297\u539f\u4e3a\u57fa\u7840\u7684DC\u75ab\u82d7\u8054\u5408NRT\u56de\u8f93\u7684\u6cbb\u7597\u65b9\u6848\uff0c\u8fc4\u4eca\u4e3a\u6b62\u5df2\u5b9e\u73b0\u8fd13\u5e74\u5b8c\u5168\u7f13\u89e3\uff08CR\uff09\u3002<\/span><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);word-wrap: break-word !important;\">\n<section style=\"margin-top: 0.5em;margin-bottom: 0.5em;padding-right: 0.5em;padding-left: 0.5em;max-width: 100%;box-sizing: border-box;text-align: center;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;width: 661.024px;box-shadow: rgb(102, 102, 102) 0.2em 0.2em 0.5em;display: inline-block;line-height: 0;border-color: white;word-wrap: break-word !important;height: auto !important;\"><img class=\"\"        style=\"box-sizing: border-box;vertical-align: middle;width: 661.024px;word-wrap: break-word !important;visibility: visible !important;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/8-1555992897.jpeg\" alt=\"\u3010\u5b66\u672f\u7814\u7a76\u3011NGS\u52a9\u529b\u65b0\u6297\u539f\u4e2a\u4f53\u5316\u514d\u75ab\u6cbb\u7597\u65b0\u6280\u672f\u7814\u7a76\" title=\"\u3010\u5b66\u672f\u7814\u7a76\u3011NGS\u52a9\u529b\u65b0\u6297\u539f\u4e2a\u4f53\u5316\u514d\u75ab\u6cbb\u7597\u65b0\u6280\u672f\u7814\u7a76\"  \/><\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;line-height: 1.5;font-size: 14px;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><span style=\"max-width: 100%;color: rgb(0, 122, 170);box-sizing: border-box !important;word-wrap: break-word !important;\">\u4e00\u4f8b\u5e7f\u6cdb\u8f6c\u79fb\u6027\u80f0\u817a\u764c\u60a3\u8005\uff0c\u5c40\u90e8\u75c5\u7076\u63a5\u53d7\u8be5\u80bf\u7624\u4e2d\u5fc3\u4f4e\u5242\u91cf\u653e\u7597\u8054\u5408\u9776\u5411KRAS G12D\u7684\u4e2a\u4f53\u5316\u514d\u75ab\u6cbb\u7597\u65b9\u6848\uff0c2.5\u4e2a\u6708\u540e\u5b9e\u73b0\u514d\u75ab\u76f8\u5173\u7684\u90e8\u5206\u7f13\u89e3\uff08irPR\uff09\u3002<\/span><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;line-height: 1.5;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box;font-size: 14px;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u4ee5\u65b0\u6297\u539f\u4e3a\u57fa\u7840\u7684\u4e2a\u4f53\u5316\u514d\u75ab\u6cbb\u7597\u6a21\u5f0f<\/span>\u7684\u5efa\u7acb\u548c\u5e94\u7528\uff0c\u6709\u671b\u52a0\u901f\u65b0\u6297\u539f\u4e3a\u57fa\u7840\u7684\u8f6c\u5316\u514d\u75ab\u6cbb\u7597\u7814\u7a76\u3002\u5357\u4eac\u9f13\u697c\u533b\u9662\u80bf\u7624\u4e2d\u5fc3\u4ee5\u6b64\u4e3a\u57fa\u7840\uff0c\u6b63\u5728\u5f00\u5c55\u7684\u65b0\u6297\u539f\u7eb3\u7c73\u75ab\u82d7\u3001\u9776\u5411\u65b0\u6297\u539f\u7684\u7279\u5f02\u6027\u7ec6\u80de\u514d\u75ab\u6cbb\u7597\u7b49\u7814\u7a76\uff0c\u6709\u671b\u5b9e\u73b0\u6211\u56fd\u5728\u8be5\u9886\u57df\u7684\u539f\u521b\u6027\u6280\u672f\u8fdb\u6b65\uff0c\u6700\u7ec8\u9020\u798f\u5e7f\u5927\u80bf\u7624\u60a3\u8005\u3002<\/span><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;line-height: 1.5;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box;font-size: 14px;word-wrap: break-word !important;\">\u5bf9\u665a\u671f\u60a3\u8005\u81ea\u8eab\u80bf\u7624\u7279\u6709\u7a81\u53d8\u8fdb\u884c\u68c0\u6d4b\uff0c\u6709\u65f6\u65e0\u6cd5\u83b7\u53d6\u80bf\u7624\u7ec4\u7ec7\u6837\u672c\uff0c\u8840\u6db2\u4e2d\u6765\u81ea\u80bf\u7624\u5404\u90e8\u4f4d\u7684ctDNA\u6837\u672c\u540c\u6837\u6709\u68c0\u6d4b\u4ef7\u503c\uff0cctDNA\u6837\u672c\u80fd\u591f\u53cd\u6620\u60a3\u8005\u7684\u603b\u4f53\u5b9e\u65f6\u7a81\u53d8\u4fe1\u606f\u3002\u7136\u800c\uff0c\u7531\u4e8ectDNA\u5360cfDNA\u76840.1%-10%\uff0c\u56e0\u6b64\u9700\u8981\u6df1\u5ea6\u6d4b\u5e8f\u8fdb\u884c\u80bf\u7624\u7279\u6709\u7a81\u53d8\u68c0\u6d4b\u3002\u76ee\u524d\u7528\u4e8e\u65b0\u751f\u6297\u539f\u9274\u5b9a\u7684\u6d4b\u5e8f\u6280\u672f\u4e3b\u8981\u4e3a\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\uff08WGS\uff09\uff0c\u5168\u5916\u663e\u5b50\u6d4b\u5e8f\uff08WES\uff09\u548c\u5168\u8f6c\u5f55\u7ec4\u6d4b\u5e8f\uff08RNA-seq\uff09\uff0c\u4f46\u8fd9\u4e9b\u6d4b\u5e8f\u6280\u672f\u7531\u4e8e\u6d4b\u5e8f\u6df1\u5ea6\u7684\u5c40\u9650\u6027\u5f88\u96be\u5e94\u7528\u4e8e\u6db2\u6001\u6d3b\u68c0\u6837\u672c\u68c0\u6d4b\u3002&gt;300\u4e2a\u57fa\u56e0\u7684\u9776\u5411\u6d4b\u5e8f\u5927panel\u53ef\u4ee5\u7528\u4e8e\u8bc4\u4f30\u80bf\u7624\u7a81\u53d8\u8d1f\u8377\u548c\u6297PD-1\u6cbb\u7597\u7597\u6548\uff0c\u53c8\u53ef\u4ee5\u6316\u6398\u8db3\u591f\u7684\u7a81\u53d8\u7528\u4e8e\u4e2a\u4f53\u5316\u65b0\u6297\u539f\u9274\u5b9a\uff0c\u540c\u65f6\u8fd8\u4e5f\u53ef\u8fdb\u884cctDNA\u6837\u672c\u7684\u6df1\u5ea6\u6d4b\u5e8f\uff0c\u8003\u8651\u5230\u4ee5\u4e0a\u539f\u56e0\uff0c<strong style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\">\u8be5\u9879\u76ee\u91c7\u7528\u4e86\u4e16\u548c\u4e00\u53f7\uff08400+\u764c\u75c7\u76f8\u5173\u57fa\u56e0\uff09<\/strong>\u5bf9\u80bf\u7624\u6837\u672c\u3001\u5faa\u73af\u80bf\u7624DNA (ctDNA)\u548c\u5339\u914d\u7684\u6b63\u5e38\u6837\u672c\u8fdb\u884c\u4e34\u5e8a\u9776\u5411\u57fa\u56e0\u7ec4\u5206\u6790\uff0c\u4ee5\u8bc6\u522b\u8db3\u591f\u7528\u4e8e\u4e2a\u4f53\u5316\u65b0\u6297\u539f\u9274\u5b9a\u7684\u80bf\u7624\u7279\u6709\u7a81\u53d8\u3002<\/span><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box;font-size: 14px;word-wrap: break-word !important;\">\u4e16\u548c\u7531\u8877\u5e0c\u671b\u4e0e\u5404\u4f4d\u4e34\u5e8a\u4e13\u5bb6\u6df1\u5165\u5408\u4f5c\uff0c\u4e3a\u4e34\u5e8a\u533b\u751f\u548c\u60a3\u8005\u63d0\u4f9b\u66f4\u5168\u9762\u7684\u7a81\u53d8\u4fe1\u606f\uff0c\u5e2e\u52a9\u9009\u62e9\u6700\u5408\u9002\u7684\u6cbb\u7597\u65b9\u6848\uff0c\u4e3a\u764c\u75c7\u60a3\u8005\u63d0\u4f9b\u66f4\u7cbe\u51c6\u7684\u4e2a\u6027\u5316\u6cbb\u7597\u3002<\/span><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;text-indent: 2em;word-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);word-wrap: break-word !important;\">\n<section style=\"margin-top: 10px;margin-bottom: 10px;max-width: 100%;box-sizing: border-box;text-align: center;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;display: inline-block;vertical-align: top;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;width: 43px;word-wrap: break-word !important;\">\n<section style=\"margin-bottom: 3px;max-width: 100%;box-sizing: border-box;width: 5px;height: 5px;background-color: rgb(60, 133, 217);word-wrap: break-word !important;\"><\/section>\n<section style=\"margin-bottom: -6px;margin-left: 3px;max-width: 100%;box-sizing: border-box;width: 40px;height: 1px;background-color: rgb(114, 114, 114);word-wrap: break-word !important;\"><\/section>\n<section style=\"margin-left: 8px;max-width: 100%;box-sizing: border-box;width: 1px;height: 25px;background-color: rgb(114, 114, 114);word-wrap: break-word !important;\"><\/section>\n<\/section>\n<section style=\"margin-top: -18px;margin-bottom: -18px;padding-right: 15px;padding-left: 15px;max-width: 100%;box-sizing: border-box;font-size: 14px;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><strong style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\u53c2\u8003\u8d44\u6599<\/strong><\/p>\n<\/section>\n<section style=\"margin-left: auto;max-width: 100%;box-sizing: border-box;width: 43px;word-wrap: break-word !important;\">\n<section style=\"margin-bottom: -6px;margin-left: 34px;max-width: 100%;box-sizing: border-box;width: 1px;height: 25px;background-color: rgb(114, 114, 114);word-wrap: break-word !important;\"><\/section>\n<section style=\"max-width: 100%;box-sizing: border-box;width: 40px;height: 1px;background-color: rgb(114, 114, 114);word-wrap: break-word !important;\"><\/section>\n<section style=\"margin-top: 3px;margin-left: auto;max-width: 100%;box-sizing: border-box;width: 5px;height: 5px;background-color: rgb(60, 133, 217);word-wrap: break-word !important;\"><\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;box-sizing: border-box;font-size: 16px;letter-spacing: 0.544px;white-space: normal;background-color: rgb(255, 255, 255);word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;word-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box;font-size: 14px;word-wrap: break-word !important;\">\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><span style=\"max-width: 100%;box-sizing: border-box;font-size: 12px;letter-spacing: 0px;word-wrap: break-word !important;\">[1]&nbsp;Chen&nbsp;F,&nbsp;Zou&nbsp;Z,&nbsp;Du&nbsp;J,&nbsp;Su&nbsp;S,&nbsp;Shao&nbsp;J,&nbsp;Meng&nbsp;F,&nbsp;Yang&nbsp;J,&nbsp;Xu&nbsp;Q,&nbsp;Ding&nbsp;N,&nbsp;Yang&nbsp;Y,&nbsp;Liu&nbsp;Q,&nbsp;Wang&nbsp;Q,&nbsp;Sun&nbsp;Z,&nbsp;Zhou&nbsp;S,&nbsp;Du&nbsp;S,&nbsp;Wei&nbsp;J,&nbsp;Liu&nbsp;B.&nbsp;&nbsp;J&nbsp;Clin&nbsp;Invest.&nbsp;2019&nbsp;Mar&nbsp;5;130.&nbsp;pii:&nbsp;99538.<\/span><\/p>\n<p style=\"max-width: 100%;box-sizing: border-box;min-height: 1em;word-wrap: break-word !important;\"><br  \/><\/p>\n<section  style=\"max-width: 100%;font-size: 16px;font-variant-numeric: normal;font-variant-east-asian: normal;letter-spacing: 0.544px;line-height: 25.6px;text-align: center;widows: 1;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section style=\"margin-bottom: 15px;max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section style=\"padding-right: 10px;padding-left: 10px;max-width: 100%;display: inline-block;vertical-align: top;border-bottom-left-radius: 0.5em;border-bottom-right-radius: 0.5em;color: rgb(255, 255, 255);background-color: rgb(13, 30, 97);box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\u5357\u4eac\u5927\u5b66\u533b\u5b66\u9662\u9644\u5c5e\u9f13\u697c\u533b\u9662\u80bf\u7624\u4e2d\u5fc3<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;font-size: 16px;font-variant-numeric: normal;font-variant-east-asian: normal;letter-spacing: 0.544px;line-height: 25.6px;text-align: center;widows: 1;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;text-align: justify;font-size: 13px;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<ul class=\"list-paddingleft-2\" style=\"\">\n<li>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\">\u56fd\u5bb6\u80bf\u7624\u4e34\u5e8a\u91cd\u70b9\u4e13\u79d1<\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;\">\u6c5f\u82cf\u7701\u6d88\u5316\u80bf\u7624\u4e34\u5e8a\u533b\u5b66\u4e2d\u5fc3<\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\u6c5f\u82cf\u7701\u80bf\u7624\u4e34\u5e8a\u91cd\u70b9\u5b66\u79d1<\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\u6c5f\u82cf\u7701\u80bf\u7624\u4e34\u5e8a\u91cd\u70b9\u4e13\u79d1<\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\u5357\u4eac\u5e02\u80bf\u7624\u4e34\u5e8a\u533b\u5b66\u4e2d\u5fc3<\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\u5357\u4eac\u5e02\u80bf\u7624\u8f6c\u5316\u533b\u5b66\u4e2d\u5fc3<\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\u5357\u4eac\u5927\u5b66\u80bf\u7624\u4e34\u5e8a\u7814\u7a76\u6240<\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\u80bf\u7624\u5b66\u535a\u58eb\u540e\u5de5\u4f5c\u7ad9<\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\u5357\u4eac\u5927\u5b66\u80bf\u7624\u5b66\u535a\u58eb\u70b9<\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\u5357\u4eac\u533b\u79d1\u5927\u5b66\u80bf\u7624\u5b66\u535a\u58eb\u70b9<\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\u5357\u4eac\u4e2d\u533b\u836f\u5927\u5b66\u80bf\u7624\u5b66\u535a\u58eb\u70b9<\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\u4e2d\u56fd\u836f\u79d1\u5927\u5b66\u80bf\u7624\u5b66\u535a\u58eb\u70b9<\/p>\n<\/li>\n<\/ul>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;font-size: 16px;font-variant-numeric: normal;font-variant-east-asian: normal;letter-spacing: 0.544px;line-height: 25.6px;text-align: center;widows: 1;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;text-align: left;font-size: 13px;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<ul class=\"list-paddingleft-2\" style=\"\">\n<li>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\u56fd\u5bb6\u9996\u6279\u80bf\u7624\u8bca\u65ad\u4e0e\u6cbb\u7597\u9879\u76ee\u9ad8\u901a\u91cf\u57fa\u56e0\u6d4b\u5e8f\u6280\u672f\u4e34\u5e8a\u5e94\u7528\u8bd5\u70b9\u5355\u4f4d<\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\u56fd\u5bb6\u5927\u578b\u533b\u7528\u8bbe\u5907\u793a\u8303\u57fa\u5730<\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\u56fd\u5bb6\u836f\u54c1\u4e34\u5e8a\u8bd5\u9a8c\u57fa\u5730<\/p>\n<\/li>\n<li>\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\u56fd\u5bb6\u9996\u6279\u653e\u5c04\u6cbb\u7597\u89c4\u8303\u5316\u57f9\u8bad\u57fa\u5730<\/p>\n<\/li>\n<\/ul>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;font-size: 16px;font-variant-numeric: normal;font-variant-east-asian: normal;letter-spacing: 0.544px;line-height: 25.6px;text-align: center;widows: 1;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<section style=\"max-width: 100%;text-align: left;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\">\n<p style=\"max-width: 100%;min-height: 1em;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"><br style=\"max-width: 100%;box-sizing: border-box !important;word-wrap: break-word !important;overflow-wrap: break-word !important;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section  style=\"max-width: 100%;font-size: 16px;font-variant-numeric: 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[&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":89991,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/89990"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=89990"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/89990\/revisions"}],"predecessor-version":[{"id":90000,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/89990\/revisions\/90000"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/89991"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=89990"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=89990"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=89990"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}