{"id":9002,"date":"2018-06-13T01:00:00","date_gmt":"2018-07-27T09:35:35","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/2018\/07\/27\/%e9%87%8d%e7%a3%85%ef%bc%81%e9%a6%96%e6%ac%be%e6%99%9a%e6%9c%9f%e5%ae%ab%e9%a2%88%e7%99%8c%e5%85%8d%e7%96%ab%e7%96%97%e6%b3%95%e4%bb%8a%e6%97%a5%e8%8e%b7%e6%89%b9\/"},"modified":"2018-07-27T17:35:36","modified_gmt":"2018-07-27T09:35:36","slug":"%e9%87%8d%e7%a3%85%ef%bc%81%e9%a6%96%e6%ac%be%e6%99%9a%e6%9c%9f%e5%ae%ab%e9%a2%88%e7%99%8c%e5%85%8d%e7%96%ab%e7%96%97%e6%b3%95%e4%bb%8a%e6%97%a5%e8%8e%b7%e6%89%b9","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/9002\/","title":{"rendered":"\u91cd\u78c5\uff01\u9996\u6b3e\u665a\u671f\u5bab\u9888\u764c\u514d\u75ab\u7597\u6cd5\u4eca\u65e5\u83b7\u6279"},"content":{"rendered":"
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\u258e\u836f\u660e<\/span><\/strong>\u5eb7\u5fb7\/\u62a5\u9053<\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/strong><\/p>\n


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\"\u91cd\u78c5\uff01\u9996\u6b3e\u665a\u671f\u5bab\u9888\u764c\u514d\u75ab\u7597\u6cd5\u4eca\u65e5\u83b7\u6279\"<\/p>\n

\u5bab\u9888\u764c\u662f\u4e00\u7c7b\u5e38\u89c1\u7684\u764c\u75c7\u3002\u636e\u7f8e\u56fd\u764c\u75c7\u534f\u4f1a\uff08American Cancer Society\uff09\u4f30\u8ba1\uff0c\u4eca\u5e74\u5168\u7f8e\u7ea6\u670913240\u540d\u65b0\u53d1\u75c5\u4f8b\uff0c\u5e76\u6709\u7ea64170\u540d\u60a3\u8005\u5c06\u6b7b\u4e8e\u8fd9\u79cd\u75be\u75c5\u3002\u4ece\u751f\u5b58\u671f\u4e0a\u770b\uff0c\u65e9\u671f\u5bab\u9888\u764c\u76845\u5e74\u751f\u5b58\u7387\u5e76\u4e0d\u4f4e\uff0cIA\u671f\u60a3\u8005\u53ef\u751f\u5b58\u7387\u9ad8\u8fbe93%\uff0cIB\u671f\u60a3\u8005\u4e5f\u670980%\u3002\u7136\u800c\u968f\u7740\u75c5\u60c5\u8fdb\u5165\u665a\u671f\uff0c\u60a3\u8005\u7684\u751f\u5b58\u7387\u4e5f\u6025\u8f6c\u76f4\u4e0b\u3002\u4e00\u65e6\u75c5\u60c5\u53d1\u5c55\u5230\u4e86IV\uff0c\u60a3\u8005\u7684\u751f\u5b58\u7387\u5c31\u9510\u51cf\u81f315%-16%\u3002<\/strong>\u5bf9\u4e8e\u665a\u671f\u5bab\u9888\u764c\u60a3\u8005\u6765\u8bf4\uff0c\u4e00\u6b3e\u65b0\u836f\u662f\u5979\u4eec\u751f\u547d\u7684\u91cd\u8981\u5e0c\u671b\u3002<\/span><\/p>\n

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Keytruda\u4f5c\u4e3a\u4e00\u6b3e\u91cd\u78c5\u514d\u75ab\u7597\u6cd5\uff0c\u5df2\u7ecf\u5728\u9ed1\u8272\u7d20\u7624\u3001\u80ba\u764c\u3001\u4ee5\u53ca\u5934\u9888\u764c\u7b49\u591a\u7c7b\u764c\u75c7\u4e2d\u8bc1\u660e\u4e86\u81ea\u5df1\u7684\u6cbb\u7597\u6f5c\u529b\u3002\u800c\u5728\u4e00\u9879\u540d\u4e3aKEYNOTE-158\u7684\u4e34\u5e8a\u8bd5\u9a8c\u91cc\uff0c\u5176\u5728\u5bab\u9888\u764c\u4e2d\u7684\u6cbb\u7597\u6548\u679c\u4e5f\u5f97\u5230\u4e86\u786e\u8ba4\u3002<\/span><\/p>\n


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\"\u91cd\u78c5\uff01\u9996\u6b3e\u665a\u671f\u5bab\u9888\u764c\u514d\u75ab\u7597\u6cd5\u4eca\u65e5\u83b7\u6279\"<\/p>\n

\u8be5\u8bd5\u9a8c\u62db\u52df\u4e8698\u540d\u590d\u53d1\u6027\u6216\u8f6c\u79fb\u6027\u5bab\u9888\u764c\u60a3\u8005\uff0c\u5e76\u63a5\u53d7\u6bcf\u4e09\u5468\u4e00\u6b21\u7684Keytruda\uff08200mg\uff09\u6cbb\u7597\u3002\u572877\u540d\uff0879%\uff09\u8868\u8fbePD-L1\uff08\u7efc\u5408\u9633\u6027\u8bc4\u5206\u4e0d\u5c0f\u4e8e1\uff09\u7684\u60a3\u8005\u4e2d\uff0cKeytruda\u53d6\u5f97\u4e8614.3%\u7684\u603b\u4f53\u7f13\u89e3\u7387\uff0895% CI\uff1a7.4% \u2013 24.1%\uff09\uff0c\u5b8c\u5168\u7f13\u89e3\u7387\u4e3a2.6%\u3002<\/strong>\u5728\u6cbb\u7597\u751f\u6548\u7684\u60a3\u8005\u4e2d\uff0c\u4e2d\u4f4d\u7f13\u89e3\u65f6\u95f4\u5c1a\u672a\u8fbe\u5230\uff0c\u4e14\u670991%\u7684\u60a3\u8005\u7f13\u89e3\u65f6\u95f4\u8d85\u8fc7\u534a\u5e74\u3002\u5728\u80bf\u7624PD-L1\u8868\u8fbe\u91cf\u4f4e\u4e8e1\u7684\u60a3\u8005\u4e2d\uff0cKeytruda\u6ca1\u6709\u5c55\u73b0\u51fa\u6548\u679c\u3002\u57fa\u4e8e\u8fd9\u4e9b\u6570\u636e\uff0c\u7f8e\u56fdFDA\u6279\u51c6\u5176\u4e0a\u5e02\uff0c\u6cbb\u7597\u5728\u5316\u7597\u540e\u75be\u75c5\u4f9d\u65e7\u51fa\u73b0\u8fdb\u5c55\uff0c\u4e14\u8868\u8fbePD-L1\u7684\u665a\u671f\u5bab\u9888\u764c\u60a3\u8005\u3002<\/span><\/p>\n

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\u201cKeytruda\u662f\u9996\u6b3e\u83b7\u6279\u6cbb\u7597\u665a\u671f\u5bab\u9888\u764c\u7684\u6297PD- 1\u7597\u6cd5\uff0c\u4e3a\u7279\u5b9a\u60a3\u8005\u5e26\u6765\u4e86\u91cd\u8981\u7684\u4e8c\u7ebf\u6cbb\u7597\u9009\u62e9<\/strong>\uff0c\u201d\u9ed8\u6c99\u4e1c\u7814\u7a76\u5b9e\u9a8c\u5ba4\u7684\u9996\u5e2d\u533b\u5b66\u5b98\u3001\u5168\u7403\u4e34\u5e8a\u5f00\u53d1\u8d1f\u8d23\u4eba\u53ca\u9ad8\u7ea7\u526f\u603b\u88c1Roy Baynes\u535a\u58eb\u8bf4\u9053\uff1a\u201c\u672c\u6b21\u6279\u51c6\u4e5f\u662fKeytruda\u5728\u5987\u79d1\u764c\u75c7\u4e0a\u83b7\u5f97\u7684\u9996\u4e2a\u9002\u5e94\u75c7\uff0c\u53cd\u6620\u4e86\u6211\u4eec\u4e3a\u5e7f\u6cdb\u7c7b\u578b\u7684\u764c\u75c7\u5e26\u6765\u521b\u65b0\u6cbb\u7597\u65b9\u6848\u7684\u627f\u8bfa\u3002\u8fd9\u5305\u62ec\u4e86\u90a3\u4e9b\u5f71\u54cd\u4e86\u5987\u5973\u7684\u764c\u75c7\u3002\u201d<\/span><\/p>\n

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\u6211\u4eec\u795d\u8d3aKeytruda\u518d\u6b21\u53d6\u5f97\u7a81\u7834\uff0c\u5e76\u671f\u5f85\u5b83\u80fd\u6539\u5584\u665a\u671f\u5bab\u9888\u764c\u60a3\u8005\u7684\u9884\u540e\uff0c\u7ed9\u5979\u4eec\u5e26\u6765\u751f\u7684\u5e0c\u671b\uff01<\/span><\/p>\n

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\u53c2\u8003\u8d44\u6599\uff1a<\/span><\/p>\n

[1] FDA Approves Merck\u2019s KEYTRUDA\u00ae (pembrolizumab) for Previously Treated Patients with Recurrent or Metastatic Cervical Cancer Whose Tumors Express PD-L1 (CPS Greater Than or Equal to 1)<\/span><\/p>\n

[2] Key Statistics for Cervical Cancer \u2013 ACS<\/span><\/p>\n

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\u59cb\u53d1\u4e8e\u5fae\u4fe1\u516c\u4f17\u53f7\uff1a \u836f\u660e\u5eb7\u5fb7 <\/p>\n<\/blockquote>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

\u258e\u836f\u660e\u5eb7\u5fb7\/\u62a5\u9053 \u4eca\u65e5\uff0c\u4e1a\u5185\u4f20\u6765\u559c\u8baf\u3002\u836f\u660e\u5eb7\u5fb7\u96c6\u56e2\u5408\u4f5c\u4f19\u4f34\u9ed8\u6c99\u4e1c\uff08MSD\uff09\u5ba3\u5e03\uff0c\u7f8e\u56fdFDA\u6279\u51c6\u5176\u91cd\u78c5\u514d\u75ab\u7597\u6cd5K […]<\/p>\n","protected":false},"author":1,"featured_media":9003,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/9002"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=9002"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/9002\/revisions"}],"predecessor-version":[{"id":9007,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/9002\/revisions\/9007"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/9003"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=9002"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=9002"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=9002"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}