{"id":90817,"date":"2019-04-18T00:00:50","date_gmt":"2019-04-23T04:22:55","guid":{"rendered":"http:\/\/www.05921.net\/index.php\/90817\/"},"modified":"2019-04-23T12:23:00","modified_gmt":"2019-04-23T04:23:00","slug":"9055e35cc3","status":"publish","type":"post","link":"https:\/\/www.05921.net\/index.php\/90817\/","title":{"rendered":"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f"},"content":{"rendered":"<div class=\"bpp-post-content\">\n<section class=\"xmteditor\" style=\"display:none;\"  ><\/section>\n<section style=\"font-size: 15px;line-height: 2.2;letter-spacing: 0.5px;padding: 0px 20px;color: rgb(99, 99, 110);box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\" >\n<section style=\"margin: 0px 0% 10px;box-sizing: border-box;\">\n<section style=\"display: inline-block;vertical-align: middle;width: 12%;box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\" >\n<section style=\"text-align: center;margin: 0px 0%;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;width: 60%;box-sizing: border-box;\"><img class=\"raw-image\"    style=\"vertical-align: middle;max-width: 100%;width: 100%;box-sizing: border-box;\" width=\"100%\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/3-1555993376.gif\" alt=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\" title=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\"  \/><\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"display: inline-block;vertical-align: middle;width: 88%;padding: 0px 0px 0px 10px;box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\" >\n<section style=\"margin: 0px 0%;box-sizing: border-box;\">\n<section style=\"font-size: 12px;color: rgb(116, 116, 128);box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\">\u70b9\u51fb\u84dd\u5b57\u5173\u6ce8\u6211\u4eec\uff0c\u966a\u60a8\u8d70\u597d\u6297\u764c\u4e4b\u8def\uff01<\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"text-align: center;margin: 0px 0% 10px;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;border-width: 0px;border-radius: 5px;border-style: none;border-color: rgb(99, 99, 110);overflow: hidden;box-sizing: border-box;\"><img class=\"raw-image\"          style=\"vertical-align: middle;max-width: 100%;box-sizing: border-box;width: 614px;height: 230px;\" src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/5-1555993376.jpeg\" alt=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\" title=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\"  \/><\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"font-size: 12px;color: rgb(132, 132, 141);box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\">\u6587\u4e28\u533b\u5b66\u90e8<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;box-sizing: border-box;\">\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">2019\u5e744\u670810\u65e5-13\u65e5\uff0c2019\u5e74\u6b27\u6d32\u80ba\u764c\u5927\u4f1a<span style=\"color: rgb(170, 170, 185);box-sizing: border-box;\">\uff08ELCC 2019\uff09<\/span>\u5728\u745e\u58eb\u65e5\u5185\u74e6\u9686\u91cd\u53ec\u5f00\u3002\u4f5c\u4e3a\u80f8\u90e8\u80bf\u7624\u4e13\u5bb6\u6700\u91cd\u8981\u7684\u591a\u5b66\u79d1\u80bf\u7624\u4f1a\u8bae\u4e4b\u4e00\uff0c\u4f17\u591a\u6700\u65b0\u4e34\u5e8a\u7814\u7a76\u7ed3\u679c\u5728\u672c\u6b21\u4f1a\u8bae\u4e2d\u516c\u5e03\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u5c0f\u7f16\u7ed9\u5927\u5bb6\u6c47\u603b\u51e0\u4e2a\u91cd\u78c5\u7814\u7a76\u7ed3\u679c\uff0c\u5e26\u5927\u5bb6\u4e86\u89e3\u80ba\u764c\u6cbb\u7597\u6700\u65b0\u8fdb\u5c55\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;box-sizing: border-box;\"><img class=\"raw-image\"    style=\"vertical-align: middle;max-width: 100%;box-sizing: border-box;\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/6-1555993376.jpeg\" alt=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\" title=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\"  \/><\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: center;font-size: 16px;box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u54ea\u51e0\u7c7b\u60a3\u8005\u4ecedurvalumab\u4e00\u7ebf\u6cbb\u7597\u4e2d\u83b7\u76ca\u66f4\u591a\uff1f<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;box-sizing: border-box;\">\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u5982\u4f55\u5ef6\u957f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u60a3\u8005\u603b\u751f\u5b58\u671f\u4e00\u76f4\u662f\u80ba\u764c\u9886\u57df\u4e13\u5bb6\u7814\u7a76\u7684\u91cd\u70b9\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u867d\u7136MYSTIC\u7684III\u671f\u4e34\u5e8a\u8bd5\u9a8c\u5f97\u51fa\u4e86\u9634\u6027\u7ed3\u679c\uff0c\u4f46\u8fdb\u4e00\u6b65\u7684\u4e9a\u7ec4\u5206\u6790\u7ed3\u679c\u8868\u660e\uff0c\u67d0\u4e9b\u6761\u4ef6\u4e0b\uff0c\u4e0e\u5316\u7597\u76f8\u6bd4\uff0c durvalumab\u4e00\u7ebf\u6cbb\u7597\u6539\u5584\u4e86\u603b\u751f\u5b58\u671f\uff08OS\uff09\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">durvalumab<\/strong>\uff08\u5546\u54c1\u540d\uff1aImfinzi\u00ae\uff09\u4e3a\u82f1\u56fd\u963f\u65af\u5229\u5eb7\u7814\u53d1\u7684PD-L1\u5355\u6297\uff0c\u81ea2017\u5e74\u52a0\u901f\u6279\u51c6\u7528\u4e8e\u5c3f\u8def\u4e0a\u76ae\u764c\uff0c2018\u5e742\u6708\u83b7\u6279\u7528\u4e8eIII\u671fNSCLC\uff0c\u76ee\u524d\u5df2\u5728\u5168\u740340\u4e2a\u56fd\u5bb6\u6216\u5730\u533a\u83b7\u6279\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;box-sizing: border-box;\">\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u6b64\u524dMYSTIC\u7684III\u671f\u4e34\u5e8a\u8bd5\u9a8c\u8868\u660e\uff0c\u5728\u8f6c\u79fb\u6027NSCLC\uff08PD-L1\u9633\u6027\u7387\uff1e25%\uff09\u60a3\u8005\u7684\u4e00\u7ebfdurvalumab\uff08\u8054\u5408\u6216\u4e0d\u8054\u5408tremelimumab\uff09\u4e0e\u5316\u7597\u76f8\u6bd4\uff0cOS\u672a\u663e\u793a\u51fa\u7edf\u8ba1\u5b66\u5dee\u5f02\uff0c\u901a\u4fd7\u7684\u8bf4\u5c31\u662f\u83b7\u76ca\u4e0d\u660e\u663e\uff0c\u9634\u6027\u7ed3\u679c\u3002\u6b64\u6b21\u516c\u5e03\u7684\u7ed3\u679c\u5728\u5bf9\u540e\u7eed\u4e0d\u540c\u6cbb\u7597\u65b9\u5f0f\u7684\u5f71\u54cd\u8fdb\u884c<span style=\"color: rgb(123, 12, 0);\"><strong>\u6821\u6b63\u540e\uff0c\u5728 PD-L1\u8868\u8fbe\uff1e25%\u7684\u60a3\u8005\u4e2d\uff0cdurvalumab\u76f8\u6bd4\u5316\u7597\u7684OS\u589e\u52a0\u4e864.7\u4e2a\u6708\uff0c\u53c8\u63d0\u9ad8\u4e861\u4e2a\u6708\u3002<\/strong><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;box-sizing: border-box;\"><img class=\"raw-image\"    style=\"vertical-align: middle;max-width: 100%;box-sizing: border-box;\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/10-1555993376.jpg\" alt=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\" title=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\"  \/><\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;box-sizing: border-box;\">\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u53e6\u5916\uff0c\u7814\u7a76\u8005\u5bf9MYSTIC\u4e34\u5e8a\u8bd5\u9a8c\u8fdb\u884c\u4e86\u4e9a\u7ec4\u5206\u6790\uff0c\u7ed3\u679c\u8868\u660e<span style=\"color: rgb(123, 12, 0);\"><strong>\uff1a<\/strong><\/span><span style=\"color: rgb(123, 12, 0);\"><strong>\u5e74\u9f8465\u5c81\u3001\u975e\u9cde\u72b6\u7ec4\u7ec7\u5b66\u7c7b\u578b\u3001PD-L1\u8868\u8fbe\uff1e25%\u3001\u4f53\u80fd\u72b6\u6001\u8bc4\u5206\u5341\u5206\u826f\u597d<\/strong><\/span>\u7b49\u60c5\u51b5\u7684\u8f6c\u79fb\u6027NSCLC\u60a3\u8005\uff0cdurvalumab\u76f8\u6bd4\u5316\u7597\u7684OS\u90fd\u6709\u83b7\u76ca\u3002\u4e0d\u8fc7\uff0cCTLA-4\u6297\u4f53tremelimumab\u7684\u4f5c\u7528\u6bd4\u8f83\u5c34\u5c2c\uff0c\u53ef\u6709\u53ef\u65e0\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u540c\u65f6\uff0c\u4ece\u6cbb\u7597\u76f8\u5173\u4e0d\u826f\u53cd\u5e94\u53d1\u751f\u7387\u6765\u770b\uff0c\u63a5\u53d7\u5316\u7597\u7684\u60a3\u80053\u7ea7\u4ee5\u4e0a\u4e0d\u826f\u53cd\u5e94\u7684\u6bd4\u4f8b\u6700\u9ad8\uff1bdurvalumab\u53d1\u751f3\u7ea7\u4ee5\u4e0a\u4e0d\u826f\u53cd\u5e94\u7684\u6bd4\u4f8b\u4e3a14.9\uff05\uff0cdurvalumab\u52a0tremelimumab\u4e3a22.9\uff05\uff0c\u5316\u7597\u4e3a33.8\uff05\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u4ee5\u4e0a\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c\u76f8\u6bd4\u4e8e\u94c2\u7c7b\u5316\u7597\uff0cdurvalumab\u7684\u4e00\u7ebf\u6cbb\u7597\u53d6\u5f97\u4e86\u4e34\u5e8a\u4e0a\u7684\u751f\u5b58\u4f18\u52bf\uff0c\u5e76\u4e14\u4e0d\u826f\u53cd\u5e94\u53d1\u751f\u7387\u4f4e\u4e8e\u94c2\u7c7b\u5316\u7597\uff0c\u5728\u672a\u6765\uff0c\u4e5f\u8bb8\u53ef\u80fd\u6210\u4e3a\u8f6c\u79fb\u6027NSCLC\u60a3\u8005\u7684\u4e00\u79cd\u6cbb\u7597\u65b9\u6848\u9009\u62e9\uff01<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;box-sizing: border-box;\"><img class=\"raw-image\"    style=\"vertical-align: middle;max-width: 100%;box-sizing: border-box;\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/5-1555993377.jpeg\" alt=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\" title=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\"  \/><\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: center;font-size: 16px;box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">PD-1\u8010\u836f\u65b0\u601d\u8def\uff0c\u5c3c\u8fbe\u5c3c\u5e03\u8054\u5408\u591a\u897f\u4ed6\u8d5b<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;box-sizing: border-box;\">\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">PD-1\/PD-L1\u7c7b\u514d\u75ab\u836f\u7269\u8010\u836f\u540e\u600e\u4e48\u529e\uff1f\u8fd9\u662f\u60a3\u8005\u548c\u5bb6\u5c5e\u975e\u5e38\u5173\u5fc3\u7684\u95ee\u9898\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u672c\u6b21\u4f1a\u8bae\u4e0a\u4e00\u79cd\u8054\u5408\u6cbb\u7597\u65b9\u6848\u5438\u5f15\u4e86\u5927\u5bb6\u7684\u5173\u6ce8\uff0c\u5c0f\u89c4\u6a21\u4e34\u5e8a\u6570\u636e\u663e\u793a\uff1a<span style=\"color: rgb(123, 12, 0);\"><strong>\u9488\u5bf9PD-1\u6297\u4f53\u8010\u836f\u7684NSCLC\u60a3\u8005\uff0c\u5c3c\u8fbe\u5c3c\u5e03\u8054\u5408\u591a\u897f\u4ed6\u8d5b\u4f5c\u4e3a\u4e09\u7ebf\u6cbb\u7597\u65b9\u6848\uff0c\u6709\u6548\u738758%\uff0c\u63a7\u5236\u738783%\u3002<\/strong><\/span><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u5c3c\u8fbe\u5c3c\u5e03<\/strong>\uff08Nintedanib\uff0cBIBF 1120\uff09\u662f\u7531\u5fb7\u56fd\u52c3\u6797\u683c\u6bb7\u683c\u7ff0\u516c\u53f8\u7814\u53d1\u7684\u8840\u7ba1\u751f\u6210\u6291\u5236\u5242\uff0c\u4f5c\u7528\u9776\u70b9\u5305\u62ecVEGFR\uff081-3\uff09\u3001FGFR\uff081-3\uff09\u3001PDGFR\uff08\u03b1\u548c\u03b2\uff09\u30022014\u5e74\uff0c\u5c3c\u8fbe\u5c3c\u5e03\u88ab\u7f8e\u56fd\u548c\u6b27\u76df\u6279\u51c6\u7528\u4e8e\u7279\u53d1\u6027\u80ba\u7ea4\u7ef4\u5316\uff08IPF\uff09\u7684\u6cbb\u7597\uff0c\u6b27\u76df\u540c\u65f6\u6279\u51c6\u5c3c\u8fbe\u5c3c\u5e03+\u591a\u897f\u4ed6\u8d5b\u7528\u4e8e\u80ba\u817a\u764c\u60a3\u8005\u7684\u4e8c\u7ebf\u6cbb\u7597\uff1b2017\u5e74\uff0c\u5c3c\u8fbe\u5c3c\u5e03\u5728\u4e2d\u56fd\u83b7\u6279\u4e0a\u5e02\uff0c\u7528\u4e8e\u7279\u53d1\u6027\u80ba\u7ea4\u7ef4\u5316\uff08IPF\uff09\u7684\u6cbb\u7597\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u6b64\u6b21\u7814\u7a76\u7eb3\u516522\u540d45-76\u5c81\u80ba\u817a\u764c\u60a3\u8005\uff084\u540d\u60a3\u8005\u6709\u8111\u8f6c\u79fb\uff09\uff0c\u5176\u4e2d\u4e00\u7ebf\u6cbb\u7597\u4e3a\u5316\u7597\u65b9\u6848\uff0c\u4e8c\u7ebf\u6cbb\u7597\u4e3aPD-1\u6297\u4f53\uff08O\u836f\u6216K\u836f\uff09\uff0c\u540e\u7eed\u6cbb\u7597\u4e3a\u5c3c\u8fbe\u5c3c\u5e03\u8054\u5408\u591a\u897f\u4ed6\u8d5b\uff0c\u7ed3\u679c\u663e\u793a\uff1a7\u540d\uff0858.3\uff05\uff09\u60a3\u8005\u53d1\u751f\u90e8\u5206\u53cd\u5e94\uff0c3\u540d\uff0825%\uff09\u60a3\u8005\u75c5\u60c5\u8868\u73b0\u7a33\u5b9a\uff0c\u75be\u75c5\u63a7\u5236\u7387\uff08DCR\uff09\u8fbe\u5230\u60ca\u4eba\u768483.3\uff05\u3002\u4e2d\u4f4d\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\u4e3a5.5\u4e2a\u6708\u3002\u4e0d\u826f\u53cd\u5e94\u65b9\u9762\uff1a3\u7ea7\u4ee5\u4e0a\u4e0d\u826f\u53cd\u5e94\u7684\u53d1\u751f\u7387\u4e3a50\uff05\uff0c\u5305\u62ec\u767d\u7ec6\u80de\u51cf\u5c11\u3001\u53e3\u8154\u708e\u75c7\u3001\u6076\u5fc3\u7b49\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;box-sizing: border-box;\"><img class=\"raw-image\"    style=\"vertical-align: middle;max-width: 100%;box-sizing: border-box;\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/7-1555993377.jpg\" alt=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\" title=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\"  \/><\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;box-sizing: border-box;\">\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u4ece\u4e0a\u8ff0\u6570\u636e\u4e2d\u6211\u4eec\u53ef\u4ee5\u770b\u5230\uff0c\u5c3c\u8fbe\u5c3c\u5e03\u4e0e\u591a\u897f\u4ed6\u8d5b\u8054\u5408\u6cbb\u7597\uff0c\u5728PD-1\u514d\u75ab\u6cbb\u7597\u8010\u836f\u540e\uff0c\u7597\u6548\u8f83\u597d\uff0c\u8868\u73b0\u51fa\u8db3\u591f\u7684\u5b89\u5168\u6027\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u5c0f\u7f16\u63d0\u9192\u5927\u5bb6\uff0c\u8be5\u4e34\u5e8a\u8bd5\u9a8c\u5c1a\u5904\u4e8e\u65e9\u671f\u9636\u6bb5\uff0c\u5165\u7ec4\u4eba\u6570\u6bd4\u8f83\u5c11\uff0c\u6570\u636e\u4ec5\u4f9b\u53c2\u8003\uff0c\u6211\u4eec\u4f1a\u8ddf\u8e2a\u66f4\u65b0\u6570\u636e\uff0c\u4e0d\u6392\u9664\u968f\u7740\u5165\u7ec4\u4eba\u6570\u589e\u52a0\uff0c\u6709\u6548\u7387\u964d\u4f4e\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;box-sizing: border-box;\"><img class=\"raw-image\"    style=\"vertical-align: middle;max-width: 100%;box-sizing: border-box;\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/5-1555993377-1.jpeg\" alt=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\" title=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\"  \/><\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: center;font-size: 16px;box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u5e74\u9f84\u8d8a\u5927\uff0c\u514d\u75ab\u6cbb\u7597\u7684\u6548\u679c\u53ef\u80fd\u8d8a\u597d<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;box-sizing: border-box;\">\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u6570\u636e\u663e\u793a\uff0c\u7ea670%\u7684\u65b0\u8bca\u65ad\u7684NSCLC\u60a3\u8005\u4e3a\u8001\u5e74\uff0c\u5176\u4e2d\u8d85\u8fc7\u4e00\u534a\u5df2\u7ecf\u5230\u8fbe\u5c40\u90e8\u665a\u671f\u6216\u8005\u53d1\u751f\u8fdc\u7aef\u8f6c\u79fb\uff0c\u8fd9\u7c7b\u60a3\u8005\u5bf9\u4e8e\u5316\u7597\u8010\u53d7\u6027\u5dee\uff0c\u6709\u6ca1\u6709\u5176\u4ed6\u65b9\u6cd5\u53ef\u4ee5\u5bf9\u6b64\u7c7b\u60a3\u8005\u80bf\u7624\u8fdb\u884c\u63a7\u5236\uff1f\u672c\u6b21\u4f1a\u8bae\u4e0a\uff0c\u4e00\u9879\u6bd4\u8f83\u8001\u5e74PD-L1\u9633\u6027\u665a\u671fNSCLC\u60a3\u8005K\u836f\u4e0e\u5316\u7597\u7597\u6548\u53ca\u5b89\u5168\u6027\u7684\u7814\u7a76\u7ed9\u4e86\u6211\u4eec\u7b54\u6848\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">Pembrolizumab<\/strong>\uff08K\u836f\uff09\u662f\u9ed8\u6c99\u4e1c\u516c\u53f8\u7684\u514d\u75ab\u836f\u7269\uff0c\u9002\u7528\u4e8e\u665a\u671f\u6076\u6027\u9ed1\u8272\u7d20\u7624\u3001\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7b49\u75be\u75c5\uff0c\u76ee\u524d\u5df2\u5728\u4e2d\u56fd\u83b7\u6279\u4e0a\u5e02\uff0c\u9002\u5e94\u75c7\u5305\u62ec\u665a\u671f\u6076\u6027\u9ed1\u8272\u7d20\u7624\u548c\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u7814\u7a76\u8005\u5bf9\u5e74\u9f84\u226518\u5c81\u60a3\u8005\u8fdb\u884cPD-L1\u9633\u6027\u8868\u8fbe\u7387\uff08PD-L1 TPS\uff09\u8bc4\u5206\uff0c\uff1e1%\u7684\u6709KEYNOTE 010, 042\u7ec4\uff0c\uff1e50%\u7684\u6709KEYNOTE 024\u7ec4\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u5bf9\u4e0a\u8ff0\u4e09\u9879\u7814\u7a76\u4e2d\uff0c\u5e74\u9f84\u226575\u5c81\u7684PD-L1\u9633\u6027\u665a\u671fNSCLC\u60a3\u8005\u8fdb\u884c\u6c47\u603b\u5206\u6790\uff0cPD-L1\u9633\u6027\u22651%\u548c\u226550%\u5206\u7ec4\u4e2d\uff0cK\u836f\u5bf9\u6bd4\u5316\u7597\u5747\u6539\u5584\u4e86\u603b\u751f\u5b58\u7387\uff08OS\uff09\uff0c\u4e14\u5927\u4e8e75\u5c81\u7684\u60a3\u8005\u7597\u6548\u66f4\u660e\u663e\uff01\u5b89\u5168\u6027\u5728\u226575\u5c81\u548c&lt;75\u5c81\u7684\u60a3\u8005\u4e2d\u76f8\u4f3c\uff0c3-5\u7ea7\u6cbb\u7597\u76f8\u5173\u7684\u4e0d\u826f\u53cd\u5e94\u4e0e\u5316\u7597\u4f4e\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;box-sizing: border-box;\"><img class=\"raw-image\"    style=\"vertical-align: middle;max-width: 100%;box-sizing: border-box;\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/0-1555993378.jpg\" alt=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\" title=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\"  \/><\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;box-sizing: border-box;\">\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u7531\u6b64\u53ef\u77e5\uff0c<strong><span style=\"color: rgb(123, 12, 0);\">\u5e74\u9f84\u8d8a\u5927\uff0c\u514d\u75ab\u6cbb\u7597\u7684\u6548\u679c\u53ef\u80fd\u8d8a\u597d\uff0c\u8001\u5e74\u60a3\u8005\u6216\u8bb8\u53ef\u4ee5\u4f18\u5148\u4f7f\u7528PD-1\u7c7b\u836f\u7269\u6cbb\u7597\u3002<\/span><\/strong><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;box-sizing: border-box;\"><img class=\"raw-image\"    style=\"vertical-align: middle;max-width: 100%;box-sizing: border-box;\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/0-1555993378.jpeg\" alt=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\" title=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\"  \/><\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: center;font-size: 16px;box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u5e03\u52a0\u66ff\u5c3c\u4e00\u7ebf\u518d\u73b0\u5353\u8d8a\u7597\u6548\u4f18\u52bf<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;box-sizing: border-box;\">\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">ALK\u57fa\u56e0\u878d\u5408\u7a81\u53d8\u662f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5e38\u89c1\u7684\u4e00\u79cd\u9a71\u52a8\u57fa\u56e0\uff0c\u5927\u7ea63%~5%\u7684NSCLC\u60a3\u8005\u4e2d\u643a\u5e26\u6709ALK\u57fa\u56e0\u91cd\u6392\u3002\u672c\u6b21\u4f1a\u8bae\u4e0a\u62a5\u9053\u7684ALTA-1L III\u671f\u7814\u7a76\uff0c\u518d\u6b21\u5c55\u73b0\u4e86\u5e03\u52a0\u66ff\u5c3c\uff08Brigatinib\uff0cAP26113\uff09\u4e00\u7ebf\u6cbb\u7597ALK\u7a81\u53d8\u60a3\u8005\u7684\u5353\u8d8a\u7597\u6548\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">ALTA-1L\u8bd5\u9a8c\u7eb3\u5165275\u4f8b\u521d\u6cbb\u60a3\u8005\uff0c\u63091:1\u968f\u673a\u63a5\u53d7\u5e03\u52a0\u66ff\u5c3c\u6216\u514b\u5511\u66ff\u5c3c\u6cbb\u7597\u3002\u9996\u6b21\u4e2d\u671f\u5206\u6790\u65f6\uff0c\u5e03\u52a0\u66ff\u5c3c\u7ec4\u4e2d\u4f4d\u968f\u8bbf\u65f6\u95f411.0\u6708\uff0c\u514b\u5511\u66ff\u5c3c\u7ec4\u4e2d\u4f4d\u968f\u8bbf\u65f6\u95f49.3\u4e2a\u6708\u3002\u5e03\u52a0\u66ff\u5c3c\u7684PFS\u9ad8\u4e8e\u514b\u5511\u66ff\u5c3c\uff0c\u9884\u8ba112\u4e2a\u6708PFS \u4e3a67%\uff0c\u514b\u5511\u66ff\u5c3c\u7684\u9884\u8ba112\u4e2a\u6708PFS \u4e3a43%\u3002<\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u72ec\u7acb\u8bc4\u4f30\u59d4\u5458\u4f1a\uff08IRC\uff09\u786e\u8ba4\u7684\u5e03\u52a0\u66ff\u5c3c ORR\u4e3a71%, \u514b\u5511\u66ff\u5c3cORR\u4e3a60%\u3002\u786e\u8ba4\u7684\u9885\u5185\u53ef\u6d4b\u91cf\u75c5\u7076ORR\u5206\u522b\u4e3a78% vs 29%\u3002\u6ca1\u6709\u53d1\u73b0\u65b0\u7684\u5b89\u5168\u6027\u95ee\u9898\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;box-sizing: border-box;\"><img class=\"raw-image\"    style=\"vertical-align: middle;max-width: 100%;box-sizing: border-box;\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/6-1555993378.jpg\" alt=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\" title=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\"  \/><\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;box-sizing: border-box;\">\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u4e8b\u5b9e\u8bc1\u660e\uff0c\u5728\u521d\u6cbbALK\u9633\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\u4e2d\uff0c\u5e03\u52a0\u66ff\u5c3c\u8f83\u514b\u5511\u66ff\u5c3c\u663e\u8457\u5ef6\u957fPFS\u3002\u5e03\u52a0\u66ff\u5c3c\u6216\u5c06\u6210\u4e3aALK\u9633\u6027NSCLC\u4e00\u7ebf\u6cbb\u7597\u4f18\u5148\u9009\u62e9\u836f\u7269\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;box-sizing: border-box;\"><img class=\"raw-image\"    style=\"vertical-align: middle;max-width: 100%;box-sizing: border-box;\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/8-1555993378.jpeg\" alt=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\" title=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\"  \/><\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: center;font-size: 16px;box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u514b\u5511\u66ff\u5c3c\u6cbb\u7597\u7684\u534a\u6570ROS1\u9633\u6027\u60a3\u8005\u6d3b\u8fc74\u5e74<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;box-sizing: border-box;\">\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">ROS1\u9633\u6027\u662f\u4e00\u79cd\u72ec\u7279\u7684\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5206\u5b50\u4e9a\u578b\uff0c\u7ea6\u5360NSCLC\u76841%\u3002PROFILE 1001\u7814\u7a76\u663e\u793a\uff0c\u514b\u5511\u66ff\u5c3c\u6cbb\u7597\u665a\u671fROS1\u9633\u6027NSCLC\u7f13\u89e3\u7387\u9ad8\u8fbe72%\uff0c\u4e2d\u4f4d\u7f13\u89e3\u65f6\u95f4\u4e3a 17.6 \u6708\uff0c\u4e2d\u4f4d\u65e0\u8fdb\u5c55\u65f6\u95f4\u4e3a 19.2 \u6708\u3002\u56e0\u6b64\uff0c\u4e2d\u56fd\u5df2\u4e8e2018\u5e74\u6279\u51c6\u514b\u5511\u66ff\u5c3c\u7528\u4e8e\u6cbb\u7597ROS1\u9633\u6027\u665a\u671fNSCLC\u60a3\u8005\u3002\u672c\u6b21\u4f1a\u8bae\u4e0a\uff0c\u7814\u7a76\u8005\u516c\u5e03\u4e86PROFILE 1001\u7814\u7a76\u8ddf\u8e2a\u6570\u636e\uff0c\u518d\u6b21\u7ed9ROS1\u9633\u6027NSCLC\u60a3\u8005\u5403\u4e86\u201c\u5b9a\u5fc3\u4e38\u201d\u3002<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"text-align: center;margin-top: 10px;margin-bottom: 10px;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;box-sizing: border-box;\"><img class=\"raw-image\"    style=\"vertical-align: middle;max-width: 100%;box-sizing: border-box;\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/6-1555993379.jpg\" alt=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\" title=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\"  \/><\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"text-align: justify;box-sizing: border-box;\">\n<p style=\"white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;\">\u6b64\u6b21\u7eb3\u516553\u4f8bROS1\u91cd\u6392\u60a3\u8005\uff0c\u91c7\u7528\u514b\u5511\u66ff\u5c3c\u4e2d\u4f4d\u6cbb\u7597\u6301\u7eed\u65f6\u95f4\u4e3a22\u4e2a\u6708\u3002\u5728\u622a\u6b62\u6570\u636e\u65f6\uff082018\u5e746\u670830\u65e5\uff09\uff0c14\u4f8b\u60a3\u8005\uff0822.6\uff05\uff09\u4ecd\u5728\u63a5\u53d7\u6cbb\u7597\u3002\u572863\u4e2a\u6708\u7684\u4e2d\u4f4d\u968f\u8bbf\u671f\u5185\u5171\u53d1\u751f26\u4f8b\u6b7b\u4ea1\uff0849.1\uff05\uff09\u3002\u4e2d\u4f4d\u603b\u751f\u5b58\u671f\uff08OS\uff09\u4e3a51\u4e2a\u6708\uff0c1\u5e74\u30012\u5e74\u548c4\u5e74\u7684\u5b58\u6d3b\u7387\u5206\u522b\u4e3a78.8\uff05\uff0c67.0\uff05\u548c50.7\uff05\u3002<span style=\"color: rgb(123, 12, 0);\"><strong>\u6d3b\u8fc74\u5e74\u7684\u60a3\u8005\u6bd4\u4f8b\u9ad8\u8fbe50.7\uff05\uff0c\u591a\u4e48\u9f13\u821e\u4eba\u5fc3\u7684\u6570\u636e\u3002<\/strong><\/span><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\"><br style=\"box-sizing: border-box;\"  \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"box-sizing: border-box;\">\n<section style=\"font-size: 12px;color: rgb(170, 170, 185);box-sizing: border-box;\">\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\">\u2014\u2014\u2014\u2014\u2014\u2014<\/p>\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\">\u53c2\u8003\u6587\u732e\uff1a<\/p>\n<p style=\"margin: 0px;padding: 0px;box-sizing: border-box;\">2019 ELCC congress. Abstracts<\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"text-align: center;margin: 10px 0%;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;width: 60%;box-sizing: border-box;\"><img class=\"raw-image\"    style=\"vertical-align: middle;max-width: 100%;width: 100%;box-sizing: border-box;\" width=\"100%\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/6-1555993379.png\" alt=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\" title=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\"  \/><\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" >\n<section style=\"margin: 0px 0% 10px;box-sizing: border-box;\">\n<section style=\"font-size: 14px;letter-spacing: 5px;color: rgb(70, 87, 114);box-sizing: border-box;\">\n<p style=\"text-align: center;margin: 0px;padding: 0px;box-sizing: border-box;\"><strong style=\"box-sizing: border-box;\">\u670d\u52a1\u9879\u76ee<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<section style=\"box-sizing: border-box;\" ><a title=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzI4MzIxOTU2Mw==&amp;mid=2247494806&amp;idx=3&amp;sn=a331aab30dd1af68520136a2e833696a&amp;chksm=eb8caf92dcfb26845bf992fe9538d7869337a9a2afa7d903d663817fec5e01ae891aa2bffcfd&amp;token=1267987756&amp;lang=zh_CN&amp;scene=21#wechat_redirect\" formlinkparm=\"&quot;https:\/\/mp.weixin.qq.com\/s?__biz=MzI4MzIxOTU2Mw==&amp;mid=2247494806&amp;idx=3&amp;sn=a331aab30dd1af68520136a2e833696a&amp;chksm=eb8caf92dcfb26845bf992fe9538d7869337a9a2afa7d903d663817fec5e01ae891aa2bffcfd&amp;token=1267987756&amp;lang=zh_CN&amp;scene=21#wechat_redirect&quot;\" href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzI4MzIxOTU2Mw==&amp;mid=2247494806&amp;idx=3&amp;sn=a331aab30dd1af68520136a2e833696a&amp;chksm=eb8caf92dcfb26845bf992fe9538d7869337a9a2afa7d903d663817fec5e01ae891aa2bffcfd&amp;token=1267987756&amp;lang=zh_CN&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"box-sizing: border-box;\" ><\/p>\n<section style=\"text-align: center;margin: 10px 0% 20px;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;border-width: 2px;border-radius: 5px;border-style: groove;border-color: rgb(250, 250, 250);box-shadow: rgb(250, 250, 250) 0px 0px 0px;width: 90%;overflow: hidden;box-sizing: border-box;\"><span class=\"js_jump_icon h5_image_link\"  style=\"top: auto;left: auto;margin: 0px;right: auto;bottom: auto;\"><img class=\"raw-image\"    style=\"vertical-align: middle;max-width: 100%;width: 100%;box-sizing: border-box;margin: 0px;\" width=\"100%\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/6-1555993379.jpeg\" alt=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\" title=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\"  \/><\/span><\/section>\n<\/section>\n<p><\/a><\/section>\n<section style=\"box-sizing: border-box;\" ><a title=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzI4MzIxOTU2Mw==&amp;mid=2247493608&amp;idx=2&amp;sn=fd4276ef940f1eb1edc3a97ca7e98a44&amp;scene=21#wechat_redirect\" formlinkparm=\"&quot;https:\/\/mp.weixin.qq.com\/s?__biz=MzI4MzIxOTU2Mw==&amp;mid=2247493608&amp;idx=2&amp;sn=fd4276ef940f1eb1edc3a97ca7e98a44&amp;scene=21#wechat_redirect&quot;\" href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzI4MzIxOTU2Mw==&amp;mid=2247493608&amp;idx=2&amp;sn=fd4276ef940f1eb1edc3a97ca7e98a44&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"box-sizing: border-box;\" ><\/p>\n<section style=\"text-align: center;margin: 10px 0% 20px;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;border-width: 2px;border-radius: 5px;border-style: groove;border-color: rgb(250, 250, 250);box-shadow: rgb(0, 0, 0) 0px 0px 0px;width: 90%;overflow: hidden;box-sizing: border-box;\"><span class=\"js_jump_icon h5_image_link\"  style=\"top: auto;left: auto;margin: 0px;right: auto;bottom: auto;\"><img class=\"raw-image\"    style=\"vertical-align: middle;max-width: 100%;width: 100%;box-sizing: border-box;margin: 0px;\" width=\"100%\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/2-1555993379.jpeg\" alt=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\" title=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\"  \/><\/span><\/section>\n<\/section>\n<p><\/a><\/section>\n<section style=\"box-sizing: border-box;\" ><a title=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzI4MzIxOTU2Mw==&amp;mid=2247491621&amp;idx=2&amp;sn=f81112744650511081c757f7845c5802&amp;scene=21#wechat_redirect\" formlinkparm=\"&quot;https:\/\/mp.weixin.qq.com\/s?__biz=MzI4MzIxOTU2Mw==&amp;mid=2247491621&amp;idx=2&amp;sn=f81112744650511081c757f7845c5802&amp;scene=21#wechat_redirect&quot;\" href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzI4MzIxOTU2Mw==&amp;mid=2247491621&amp;idx=2&amp;sn=f81112744650511081c757f7845c5802&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"box-sizing: border-box;\" ><\/p>\n<section style=\"text-align: center;margin: 10px 0% 20px;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;border-width: 2px;border-radius: 5px;border-style: groove;border-color: rgb(250, 250, 250);box-shadow: rgb(0, 0, 0) 0px 0px 0px;width: 90%;overflow: hidden;box-sizing: border-box;\"><span class=\"js_jump_icon h5_image_link\"  style=\"top: auto;left: auto;margin: 0px;right: auto;bottom: auto;\"><img class=\"raw-image\"    style=\"vertical-align: middle;max-width: 100%;width: 100%;box-sizing: border-box;margin: 0px;\" width=\"100%\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/3-1555993379.jpeg\" alt=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\" title=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\"  \/><\/span><\/section>\n<\/section>\n<p><\/a><\/section>\n<section style=\"box-sizing: border-box;\" ><a title=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzI4MzIxOTU2Mw==&amp;mid=2247492477&amp;idx=2&amp;sn=d12ce7450e7a9c8f24bf7c1bf43a13f9&amp;scene=21#wechat_redirect\" formlinkparm=\"&quot;https:\/\/mp.weixin.qq.com\/s?__biz=MzI4MzIxOTU2Mw==&amp;mid=2247492477&amp;idx=2&amp;sn=d12ce7450e7a9c8f24bf7c1bf43a13f9&amp;scene=21#wechat_redirect&quot;\" href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzI4MzIxOTU2Mw==&amp;mid=2247492477&amp;idx=2&amp;sn=d12ce7450e7a9c8f24bf7c1bf43a13f9&amp;scene=21#wechat_redirect\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"box-sizing: border-box;\" ><\/p>\n<section style=\"text-align: center;margin: 10px 0% 20px;box-sizing: border-box;\">\n<section style=\"max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;border-width: 2px;border-radius: 5px;border-style: groove;border-color: rgb(250, 250, 250);box-shadow: rgb(0, 0, 0) 0px 0px 0px;width: 90%;overflow: hidden;box-sizing: border-box;\"><span class=\"js_jump_icon h5_image_link\"  style=\"top: auto;left: auto;margin: 0px;right: auto;bottom: auto;\"><img class=\"raw-image\"    style=\"vertical-align: middle;max-width: 100%;width: 100%;box-sizing: border-box;margin: 0px;\" width=\"100%\"  src=\"http:\/\/www.05921.net\/wp-content\/uploads\/2019\/04\/4-1555993380.jpeg\" alt=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\" title=\"\u6b27\u6d32\u80ba\u764c\u4f1a\u8bae\uff0c\u54ea\u4e9b\u7814\u7a76\u6700\u91cd\u8981\uff1f\"  \/><\/span><\/section>\n<\/section>\n<p><\/a><\/section>\n<\/section><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u70b9\u51fb\u84dd\u5b57\u5173\u6ce8\u6211\u4eec\uff0c\u966a\u60a8\u8d70\u597d\u6297\u764c\u4e4b\u8def\uff01 \u6587\u4e28\u533b\u5b66\u90e8 2019\u5e744\u670810\u65e5-13\u65e5\uff0c2019\u5e74\u6b27\u6d32\u80ba\u764c\u5927\u4f1a\uff08ELC [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":90818,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[2],"tags":[],"_links":{"self":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/90817"}],"collection":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/comments?post=90817"}],"version-history":[{"count":1,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/90817\/revisions"}],"predecessor-version":[{"id":90836,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/posts\/90817\/revisions\/90836"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media\/90818"}],"wp:attachment":[{"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/media?parent=90817"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/categories?post=90817"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.05921.net\/index.php\/wp-json\/wp\/v2\/tags?post=90817"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}